Receptor
PDB id Resolution Class Description Source Keywords
3FW3 1.72 Å EC: 4.2.1.1 CRYSTAL STRUCTURE OF SOLUBLE DOMAIN OF CA4 IN COMPLEX WITH D HOMO SAPIENS STRUCTURE-BASED DRUG DESIGN. SMALL MOLECULE COMPLEX. CO-CRYSMEMBRANE DISEASE MUTATION GLYCOPROTEIN GPI-ANCHOR LIPOPLYASE MEMBRANE METAL-BINDING POLYMORPHISM RETINITIS PIGSENSORY TRANSDUCTION VISION ZINC
Ref.: THIOETHER BENZENESULFONAMIDE INHIBITORS OF CARBONIC ANHYDRASES II AND IV: STRUCTURE-BASED DRUG DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION. BIOORG.MED.CHEM. V. 18 3307 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ETS A:302;
B:303;
Valid;
Valid;
none;
none;
ic50 = 43 nM
324.44 C10 H16 N2 O4 S3 CCN[C...
GLC A:304;
Valid;
none;
submit data
180.156 C6 H12 O6 C([C@...
SO4 A:305;
B:306;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
ZN A:300;
B:301;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3FW3 1.72 Å EC: 4.2.1.1 CRYSTAL STRUCTURE OF SOLUBLE DOMAIN OF CA4 IN COMPLEX WITH D HOMO SAPIENS STRUCTURE-BASED DRUG DESIGN. SMALL MOLECULE COMPLEX. CO-CRYSMEMBRANE DISEASE MUTATION GLYCOPROTEIN GPI-ANCHOR LIPOPLYASE MEMBRANE METAL-BINDING POLYMORPHISM RETINITIS PIGSENSORY TRANSDUCTION VISION ZINC
Ref.: THIOETHER BENZENESULFONAMIDE INHIBITORS OF CARBONIC ANHYDRASES II AND IV: STRUCTURE-BASED DRUG DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION. BIOORG.MED.CHEM. V. 18 3307 2010
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 3F7U ic50 = 246 nM AG4 C16 H19 N3 O4 S2 COCCCNC(=O....
2 3FW3 ic50 = 43 nM ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
3 3F7B ic50 = 64 nM AG5 C20 H19 N3 O3 S2 c1ccc(cc1)....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 3F7U ic50 = 246 nM AG4 C16 H19 N3 O4 S2 COCCCNC(=O....
2 3FW3 ic50 = 43 nM ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
3 3F7B ic50 = 64 nM AG5 C20 H19 N3 O3 S2 c1ccc(cc1)....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3F7U ic50 = 246 nM AG4 C16 H19 N3 O4 S2 COCCCNC(=O....
2 3FW3 ic50 = 43 nM ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ETS; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 ETS 1 1
2 MTS 0.696429 0.861538
3 PTS 0.533333 0.873016
4 AL4 0.434211 0.818182
5 BZ1 0.417722 0.797468
Ligand no: 2; Ligand: GLC; Similar ligands found: 141
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL 1 1
2 BMA 1 1
3 GXL 1 1
4 GLA 1 1
5 ALL 1 1
6 GLC 1 1
7 BGC 1 1
8 GIV 1 1
9 MAN 1 1
10 WOO 1 1
11 32O 0.653846 0.866667
12 RIB 0.653846 0.866667
13 FUB 0.653846 0.866667
14 Z6J 0.653846 0.866667
15 AHR 0.653846 0.866667
16 BMA BMA MAN 0.545455 0.823529
17 GLA BGC 0.511628 0.848485
18 LAK 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 GLA GLC 0.511628 0.848485
23 GAL GAL 0.511628 0.848485
24 MLB 0.511628 0.848485
25 BMA GLA 0.511628 0.848485
26 BMA BMA BMA BMA BMA BMA MAN 0.5 0.823529
27 YDR 0.5 0.8
28 MAN BMA BMA BMA BMA BMA 0.5 0.823529
29 GLC GLC GLC GLC BGC 0.488889 0.848485
30 GLC GLC GLC 0.488889 0.848485
31 MAN MAN MAN 0.488889 0.848485
32 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
33 BGP 0.461538 0.675
34 G6P 0.461538 0.675
35 M6P 0.461538 0.675
36 A6P 0.461538 0.675
37 M6D 0.461538 0.675
38 BG6 0.461538 0.675
39 SHG 0.457143 0.875
40 GAF 0.457143 0.875
41 G2F 0.457143 0.875
42 X6X 0.457143 0.777778
43 2FG 0.457143 0.875
44 G3F 0.457143 0.875
45 PA1 0.457143 0.777778
46 1GN 0.457143 0.777778
47 GCS 0.457143 0.777778
48 2H5 0.457143 0.875
49 LB2 0.454545 0.848485
50 BGC BMA 0.454545 0.848485
51 BGC GAL 0.454545 0.848485
52 MAL 0.454545 0.848485
53 GLC GAL 0.454545 0.848485
54 M3M 0.454545 0.848485
55 GLA GAL 0.454545 0.848485
56 MAB 0.454545 0.848485
57 GLC BGC 0.454545 0.848485
58 BMA BMA 0.454545 0.848485
59 LBT 0.454545 0.848485
60 MAL MAL 0.454545 0.823529
61 CBK 0.454545 0.848485
62 GLA GLA 0.454545 0.848485
63 MAN GLC 0.454545 0.848485
64 CBI 0.454545 0.848485
65 N9S 0.454545 0.848485
66 GAL GLC 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 B2G 0.454545 0.848485
69 BGC GLC 0.454545 0.848485
70 LAT 0.454545 0.848485
71 GAL BGC 0.454545 0.848485
72 3MG 0.444444 0.875
73 TCB 0.444444 0.8
74 GLC SGC 0.444444 0.8
75 YIO 0.441176 0.870968
76 2GS 0.432432 0.875
77 BGC BGC 0.431818 0.848485
78 2M4 0.431818 0.848485
79 MAN MAN 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 CT3 0.416667 0.848485
84 GLC BGC GLC 0.416667 0.848485
85 MLR 0.416667 0.848485
86 GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
87 GLC GLC GLC GLC GLC 0.416667 0.848485
88 GAL FUC 0.416667 0.848485
89 BMA BMA BMA 0.416667 0.848485
90 CTR 0.416667 0.848485
91 BGC GLC GLC 0.416667 0.848485
92 BGC GLC GLC GLC GLC 0.416667 0.848485
93 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
94 GLC GAL GAL 0.416667 0.848485
95 B4G 0.416667 0.848485
96 CEX 0.416667 0.848485
97 MAN BMA BMA BMA BMA 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
100 CTT 0.416667 0.848485
101 GLC GLC BGC 0.416667 0.848485
102 DXI 0.416667 0.848485
103 GLC GLC BGC GLC GLC GLC GLC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
107 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
108 MTT 0.416667 0.848485
109 BMA MAN BMA 0.416667 0.848485
110 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
111 CE5 0.416667 0.848485
112 GAL GAL GAL 0.416667 0.848485
113 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
114 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
115 GLA GAL GLC 0.416667 0.848485
116 CE6 0.416667 0.848485
117 GLC BGC BGC BGC BGC 0.416667 0.848485
118 GLC BGC BGC 0.416667 0.848485
119 MAN BMA BMA 0.416667 0.848485
120 MT7 0.416667 0.848485
121 GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
122 CE8 0.416667 0.848485
123 CEY 0.416667 0.848485
124 BGC BGC BGC 0.408163 0.848485
125 BGC BGC BGC BGC BGC 0.408163 0.848485
126 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
127 SGC SGC BGC 0.408163 0.8
128 GLC BGC BGC BGC 0.408163 0.848485
129 BGC BGC BGC ASO BGC BGC ASO 0.408163 0.848485
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 TRE 0.405405 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 BM3 0.404762 0.7
135 NDG 0.404762 0.7
136 NAG 0.404762 0.7
137 HSQ 0.404762 0.7
138 A2G 0.404762 0.7
139 NGA 0.404762 0.7
140 FUB AHR AHR 0.4 0.764706
141 AHR AHR AHR 0.4 0.764706
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3FW3; Ligand: GLC; Similar sites found: 137
This union binding pocket(no: 1) in the query (biounit: 3fw3.bio1) has 6 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2ALG DAO 0.04099 0.41385 None
2 2ALG HP6 0.04099 0.41385 None
3 1XX6 ADP 0.03934 0.42445 1.04712
4 5COU ATP 0.02061 0.42064 1.12782
5 2IMF GSH 0.01092 0.47415 1.47783
6 2IMF TOM 0.01092 0.47415 1.47783
7 2B9H ADP 0.01465 0.41245 1.50376
8 4CS4 AXZ 0.005597 0.525 1.8797
9 5TT5 NAD 0.007894 0.47007 1.8797
10 5E72 SAM 0.005658 0.44769 1.8797
11 4M0R 644 0.04847 0.42163 1.8797
12 3PE2 E1B 0.04029 0.4195 1.8797
13 4C0X AQN 0.0299 0.42602 1.97044
14 4C0X FMN 0.02552 0.42602 1.97044
15 1IM8 SAI 0.00973 0.45174 2.04918
16 1PR9 NAP 0.04086 0.42469 2.04918
17 3D3W NAP 0.038 0.42256 2.04918
18 3QP4 HL0 0.02842 0.40084 2.1978
19 1U7Z PMT 0.03767 0.41126 2.21239
20 1FS5 16G 0.005535 0.50646 2.25564
21 2PTZ PAH 0.003243 0.48776 2.25564
22 1XMV ADP 0.04462 0.45429 2.25564
23 1ZGA HMK 0.009246 0.44837 2.25564
24 4CTA ATP 0.01384 0.43081 2.25564
25 2OWZ F6P 0.032 0.42458 2.25564
26 2Q8M AMP 0.04862 0.41872 2.25564
27 3DER ALA LYS 0.04393 0.40765 2.25564
28 4HVA 4HV 0.02356 0.41541 2.26415
29 2FPU HSO 0.01333 0.40699 2.27273
30 2P8O BVA 0.02384 0.4379 2.29008
31 1O0D 163 0.01448 0.46721 2.3166
32 1C4U IH1 0.03567 0.44265 2.3166
33 1KHT AMP 0.02304 0.40775 2.60417
34 4CC6 L5Y 0.007421 0.43097 2.63158
35 3DDN HPV 0.04433 0.41642 2.63158
36 1B8U NAD 0.03994 0.40493 2.63158
37 3P9C SAH 0.03012 0.47134 3.00752
38 1ITZ TPP 0.002058 0.45594 3.00752
39 2W62 BGC BGC BGC BGC BGC 0.02411 0.43002 3.00752
40 1KYZ SAH 0.04071 0.42659 3.00752
41 1I2B USQ 0.03301 0.414 3.00752
42 1I2B UPG 0.03301 0.414 3.00752
43 1I2B NAD 0.03301 0.414 3.00752
44 4I54 1C1 0.03265 0.41089 3.00752
45 3MD0 GDP 0.03877 0.40862 3.00752
46 3QP6 HL6 0.03105 0.42604 3.01887
47 1DAK DPU 0.02273 0.44735 3.125
48 1DAK ADP 0.02273 0.44735 3.125
49 1RYA GDP 0.01165 0.42853 3.125
50 1E4X VAL VAL SER HIS PHE ASN ASP 0.01017 0.4551 3.22581
51 5F1H 5U6 0.006479 0.40704 3.25203
52 1PIP SIN GLN VAL VAL ALA ALA NIT 0.01524 0.40081 3.30189
53 1DY4 SNP 0.00214 0.48313 3.38346
54 5XHA FRU FRU 0.008062 0.45993 3.38346
55 3B1F NAD 0.03797 0.44725 3.38346
56 1P72 ADP 0.04897 0.43684 3.38346
57 1P72 THM 0.03745 0.41779 3.38346
58 3CXO 1N5 0.04703 0.41308 3.38346
59 4WBD CIT 0.02003 0.40585 3.38346
60 3C88 ARG ARG GLY CYS NH2 0.00993 0.40449 3.38346
61 1I7L ATP 0.0431 0.40277 3.38346
62 2Z9C FMN 0.02945 0.41224 3.5
63 2Z9C DTC 0.03755 0.41224 3.5
64 1S68 AMP 0.03198 0.407 3.61446
65 1WKL ADP 0.03148 0.40321 3.64964
66 3D91 REM 0.02396 0.47435 3.7594
67 4EPM AMP 0.02726 0.45269 3.7594
68 4QCK ASD 0.02282 0.44899 3.7594
69 1RYI FAD 0.01172 0.44084 3.7594
70 5MDH NAD 0.0204 0.42906 3.7594
71 4C25 13P 0.03591 0.43795 3.77358
72 5AFN OJD 0.03865 0.41368 3.86473
73 3CBG SAH 0.01134 0.42709 3.87931
74 5W2I I3P 0.03408 0.42104 3.89105
75 5W2I ADP 0.03408 0.42104 3.89105
76 5DTF 5CT 0.003006 0.4191 3.91304
77 3B20 NAD 0.02173 0.44683 4.13534
78 2D2I NAP 0.01763 0.44164 4.13534
79 3DAG FEG 0.03984 0.4348 4.13534
80 4E93 GUI 0.01664 0.41745 4.13534
81 4HPP GLU 0.04972 0.4131 4.13534
82 1TZD ADP 0.01849 0.40499 4.13534
83 4DX5 MIY 0.0413 0.40534 4.14201
84 2AE2 NAP 0.03803 0.4439 4.23077
85 2AE2 PTO 0.03803 0.4439 4.23077
86 1ZJ6 G3D 0.00723 0.43108 4.27807
87 1B74 DGN 0.004562 0.41639 4.33071
88 4U9W COA 0.02987 0.42965 4.34783
89 1HV9 UD1 0.02794 0.46004 4.51128
90 4TTS 6DD 0.0121 0.45144 4.51128
91 1UDB NAD 0.034 0.45046 4.51128
92 1UDB UFG 0.034 0.45046 4.51128
93 3H22 B53 0.0297 0.43845 4.51128
94 3LST SAH 0.03893 0.43841 4.51128
95 1CSI OAA 0.01236 0.41454 4.51128
96 1CSI CMX 0.01236 0.41454 4.51128
97 5LJ0 6XX 0.02894 0.41185 4.61538
98 4M7F BM3 0.006332 0.48547 4.86726
99 2WK1 SAH 0.006567 0.45501 4.88722
100 1WUR 8DG 0.04512 0.40738 5
101 2HNK SAH 0.00816 0.46186 5.02092
102 5G4R LF1 0.009233 0.40429 5.08475
103 3EQO LGC 0.007478 0.42512 5.26316
104 3PN1 IVH 0.01514 0.41323 5.26316
105 1X92 M7P 0.02665 0.40947 5.52764
106 2R7K AMZ 0.04057 0.42302 5.6391
107 5FI4 5XV 0.02436 0.41112 5.6391
108 1B8O IMH 0.02335 0.40412 5.6391
109 2BVE PH5 0.007723 0.40839 5.88235
110 4YNU FAD 0.02397 0.43218 6.01504
111 4YNU LGC 0.02659 0.43218 6.01504
112 1FP1 SAH 0.001639 0.44953 6.76692
113 3KLL MAL 0.01912 0.41632 6.76692
114 2DWU DGL 0.01955 0.40682 6.76692
115 1XP8 AGS 0.01341 0.47337 7.14286
116 3VPD ANP 0.02693 0.45731 7.14286
117 4AGQ P96 0.03001 0.40353 7.30594
118 1KDK DHT 0.01402 0.4786 7.34463
119 2CWH NDP 0.01096 0.44515 7.89474
120 2CWH PYC 0.01294 0.44515 7.89474
121 1TU3 GNP 0.03798 0.4292 8.18713
122 3ZLB ANP 0.00648 0.43454 8.27068
123 2AQJ FAD 0.02713 0.46238 9.02256
124 2AQJ TRP 0.0266 0.46238 9.02256
125 5UOX 8GY 0.03653 0.41435 9.02256
126 4CKL SM8 0.01558 0.45571 9.3985
127 2WIC GNP 0.04655 0.40319 9.73783
128 5EY0 GTP 0.01795 0.40179 11.3139
129 3EW2 BTN 0.01831 0.43917 11.8519
130 1JNR FAD 0.02939 0.4512 12
131 3I28 34N 0.01419 0.44798 12.0301
132 4X9M FAD 0.0215 0.40287 12.406
133 1NU4 MLA 0.006112 0.45693 14.433
134 1DKU ABM 0.01355 0.46395 15.0376
135 1NVV GNP 0.04613 0.44449 15.4135
136 1VE3 SAM 0.01186 0.41671 17.1806
137 2DTJ THR 0.01359 0.41368 17.4157
Pocket No.: 2; Query (leader) PDB : 3FW3; Ligand: ETS; Similar sites found: 60
This union binding pocket(no: 2) in the query (biounit: 3fw3.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1W6P NDG GAL 0.007869 0.41707 None
2 3OYW TDG 0.003585 0.41177 None
3 3SAO NKN 0.007543 0.41164 None
4 4IAW LIZ 0.00994 0.4057 1.06383
5 4EIP K2C 0.01769 0.43028 1.8797
6 4EIP FAD 0.01769 0.43028 1.8797
7 3AVR OGA 0.01665 0.40091 1.8797
8 4P7X YCP 0.01432 0.40244 2.25564
9 4P7X AKG 0.01432 0.40244 2.25564
10 2GJ5 VD3 0.01942 0.41915 2.46914
11 5IXH OTP 0.0466 0.40375 2.48447
12 2WPF WPF 0.04411 0.43084 2.63158
13 4AZT LY2 0.009295 0.4027 2.63158
14 4ZOM 4Q3 0.03056 0.40002 2.66667
15 2GQR ADP 0.003669 0.42874 2.95359
16 2GQS ADP 0.004838 0.42301 2.95359
17 3W8X FTK 0.00495 0.41798 3.00752
18 4JNA FAD 0.02725 0.41699 3.00752
19 1OLM VTQ 0.01947 0.40863 3.00752
20 2AGC DAO 0.0002629 0.4813 3.08642
21 2A1L PCW 0.03497 0.41124 3.38346
22 1AUA BOG 0.01447 0.4023 3.38346
23 5EPQ OLA 0.008727 0.41078 3.65854
24 5DRB 5FJ 0.01744 0.42811 3.7594
25 4I9B 1KA 0.003858 0.40689 3.7594
26 1YKD CMP 0.01168 0.40671 3.7594
27 4ZU4 4TG 0.01195 0.40424 4.05405
28 4USF 6UI 0.01303 0.41302 4.13534
29 5J75 6GQ 0.004318 0.42536 4.16667
30 4WN5 MVC 0.00589 0.4284 4.34783
31 4MLO PAM 0.009175 0.4076 4.51128
32 5T7I LAT NAG GAL 0.003536 0.40239 4.51613
33 4Y24 TD2 0.0091 0.40313 4.54545
34 3S7O LBV 0.01702 0.41662 4.88722
35 2CDO GAL AAL GAL AAL GAL AAL 0.02368 0.4001 5
36 5IQT AKG 0.02305 0.40218 5.26316
37 3G6K POP 0.03499 0.40058 5.6391
38 3G6K FAD 0.03499 0.40058 5.6391
39 3PFG TLO 0.01285 0.4324 6.01504
40 4MNS 2AX 0.02134 0.42593 6.91824
41 3VQ2 LP4 LP5 MYR DAO 0.007092 0.44686 6.94444
42 2E56 MYR 0.01556 0.41739 6.94444
43 4OPC FDA 0.04349 0.432 7.14286
44 4OPC PGT 0.04836 0.432 7.14286
45 2CM4 RCL 0.001252 0.45947 7.33333
46 4XBA 5GP 0.009949 0.40593 7.5
47 4XBA GMP 0.01187 0.40006 7.5
48 3ZJX BOG 0.01782 0.4016 7.89474
49 5FPX GLY SER SER HIS HIS HIS HIS HIS 0.0007698 0.4124 8.84956
50 2ZMF CMP 0.01447 0.4041 8.99471
51 4CCN OGA 0.007007 0.41863 9.02256
52 4CCO OGA 0.01209 0.40617 9.02256
53 3PUR 2HG 0.01306 0.40742 9.77444
54 5U98 1KX 0.01847 0.4232 10.1504
55 2OVD DAO 0.008019 0.41673 10.4396
56 2YG2 FLC 0.01476 0.41328 11.6279
57 2YG2 S1P 0.0139 0.41006 11.6279
58 4XT2 43L 0.006581 0.42603 17.3554
59 5EOB 5QQ 0.0161 0.43556 19.9248
60 4TWL ASC 0.00000000837 0.64969 44.7154
Pocket No.: 3; Query (leader) PDB : 3FW3; Ligand: ETS; Similar sites found: 25
This union binding pocket(no: 3) in the query (biounit: 3fw3.bio2) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1C1L GAL BGC 0.02387 0.40328 None
2 2X32 OTP 0.03056 0.40019 1.67598
3 3PE2 E1B 0.01137 0.41983 1.8797
4 5ML3 DL3 0.006576 0.42412 2.01342
5 3EKK GS2 0.01203 0.41089 2.25564
6 1ZB6 GST 0.01034 0.4068 2.25564
7 3PDT ADP 0.009016 0.40598 2.63158
8 3KV5 OGA 0.01947 0.40176 2.63158
9 3KA2 2NC 0.0352 0.4003 2.95567
10 3E2M E2M 0.03603 0.40263 3.24324
11 5C5T AKG 0.02057 0.40064 3.94737
12 2WA4 069 0.002995 0.43245 4.13534
13 3AJH BL3 0.004274 0.41686 4.43548
14 3SHR CMP 0.001993 0.4457 4.51128
15 1GUI BGC BGC BGC BGC BGC BGC 0.01708 0.40902 4.51613
16 3MTX PGT 0.01135 0.40749 4.63576
17 1EPB REA 0.00829 0.40392 4.87805
18 5F3I 5UJ 0.02565 0.40916 5.26316
19 4D06 NAR 0.007615 0.4022 6.76692
20 4OFG PCG 0.003278 0.43061 7.63889
21 4KU7 PCG 0.004813 0.42275 7.84314
22 3LVW GSH 0.02019 0.40046 7.89474
23 3PNA CMP 0.004943 0.43142 9.09091
24 2Z5Y HRM 0.01603 0.40605 10.1504
25 3G08 FEE 0.03042 0.40555 17.1717
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