Receptor
PDB id Resolution Class Description Source Keywords
6JZ2 1.29 Å EC: 3.-.-.- B-GLUCURONIDASE FROM RUMINOCOCCUS GNAVUS IN COMPLEX WITH URO ISOFAGOMINE AT 1.3 ANGSTROMS RESOLUTION RUMINOCOCCUS GNAVUS B-GLUCURONIDASE HYDROLASE
Ref.: SUBSTITUENT POSITION OF IMINOCYCLITOLS DETERMINES T POTENCY AND SELECTIVITY FOR GUT MICROBIAL XENOBIOTIC-REACTIVATING ENZYMES. J.MED.CHEM. V. 63 4617 2020
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MRD A:702;
B:704;
B:702;
 Invalid;
Invalid;
Invalid;
 none;
none;
none;
 submit data
118.174 C6 H14 O2 C[C@H...
MPD B:703;
B:705;
 Invalid;
Invalid;
 none;
none;
 submit data
118.174 C6 H14 O2 C[C@@...
SJ5 B:701;
A:701;
 Valid;
Valid;
 none;
none;
 submit data
161.156 C6 H11 N O4 C1[C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6JZ2 1.29 Å EC: 3.-.-.- B-GLUCURONIDASE FROM RUMINOCOCCUS GNAVUS IN COMPLEX WITH URO ISOFAGOMINE AT 1.3 ANGSTROMS RESOLUTION RUMINOCOCCUS GNAVUS B-GLUCURONIDASE HYDROLASE
Ref.: SUBSTITUENT POSITION OF IMINOCYCLITOLS DETERMINES T POTENCY AND SELECTIVITY FOR GUT MICROBIAL XENOBIOTIC-REACTIVATING ENZYMES. J.MED.CHEM. V. 63 4617 2020
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 312 families.
1 6JZ5 - BDP C6 H10 O7 [C@@H]1([C....
2 6JZ7 - CKU C9 H17 N O4 CCCN1C[C@@....
3 6JZ3 - CN0 C6 H11 N O5 C1[C@@H]([....
4 6JZ4 - EVA C6 H9 N O6 [C@@H]1([C....
5 6JZ6 - CKX C9 H17 N O4 CCC[C@H]1[....
6 6JZ8 - GCB C6 H8 O7 [C@@H]1([C....
7 6JZ2 - SJ5 C6 H11 N O4 C1[C@@H]([....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 261 families.
1 6JZ5 - BDP C6 H10 O7 [C@@H]1([C....
2 6JZ7 - CKU C9 H17 N O4 CCCN1C[C@@....
3 6JZ3 - CN0 C6 H11 N O5 C1[C@@H]([....
4 6JZ4 - EVA C6 H9 N O6 [C@@H]1([C....
5 6JZ6 - CKX C9 H17 N O4 CCC[C@H]1[....
6 6JZ8 - GCB C6 H8 O7 [C@@H]1([C....
7 6JZ2 - SJ5 C6 H11 N O4 C1[C@@H]([....
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 3K4D Ki = 7750 nM EVA C6 H9 N O6 [C@@H]1([C....
2 5CZK Ki = 1.9 uM 57Z C21 H23 N3 O3 S Cc1cc(c2c(....
3 3LPF Ki = 208 nM Z77 C22 H25 N3 O3 S Cc1cc2c(cc....
4 6JZ5 - BDP C6 H10 O7 [C@@H]1([C....
5 6JZ7 - CKU C9 H17 N O4 CCCN1C[C@@....
6 6JZ3 - CN0 C6 H11 N O5 C1[C@@H]([....
7 6JZ4 - EVA C6 H9 N O6 [C@@H]1([C....
8 6JZ6 - CKX C9 H17 N O4 CCC[C@H]1[....
9 6JZ8 - GCB C6 H8 O7 [C@@H]1([C....
10 6JZ2 - SJ5 C6 H11 N O4 C1[C@@H]([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SJ5; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 SJ5 1 1
2 3RK 0.433333 0.820513
Similar Ligands (3D)
Ligand no: 1; Ligand: SJ5; Similar ligands found: 1119
No: Ligand Similarity coefficient
1 DBH 0.9870
2 3M0 0.9794
3 IJZ 0.9788
4 3HA 0.9771
5 3F0 0.9750
6 FE DB1 0.9714
7 IFM 0.9709
8 BE2 0.9703
9 3FH 0.9694
10 K5W 0.9691
11 OXZ 0.9685
12 CN0 0.9677
13 SAL 0.9669
14 DFB 0.9652
15 HXX 0.9652
16 BDP 0.9651
17 AZF 0.9651
18 FOT 0.9634
19 6F0 0.9629
20 VNJ 0.9600
21 GRE 0.9589
22 GCB 0.9588
23 GCU 0.9586
24 ASO 0.9584
25 GAB 0.9584
26 3OC 0.9572
27 ES6 0.9569
28 HHA 0.9558
29 3U4 0.9557
30 DOR 0.9551
31 3NT 0.9544
32 FBT 0.9542
33 ORO 0.9540
34 NOJ 0.9539
35 IP0 0.9533
36 F81 0.9506
37 3IT 0.9505
38 GLC 0.9496
39 G2F 0.9492
40 OVV 0.9490
41 G5V 0.9481
42 Q6T 0.9479
43 JKE 0.9477
44 23A 0.9473
45 3HB 0.9473
46 5RG 0.9472
47 F05 0.9471
48 D1X 0.9469
49 BEZ 0.9466
50 DMJ 0.9462
51 RHU 0.9460
52 JBK 0.9457
53 SRT 0.9456
54 53C 0.9454
55 9DG 0.9453
56 DIU 0.9448
57 GUN 0.9448
58 IFL 0.9442
59 6M1 0.9440
60 YCP 0.9437
61 RAM 0.9435
62 LCN 0.9431
63 HJP 0.9429
64 BZX 0.9426
65 FB1 0.9425
66 BGC 0.9424
67 NOY 0.9422
68 3DM 0.9420
69 0R0 0.9420
70 FBV 0.9418
71 NCA 0.9417
72 HY3 0.9410
73 25W 0.9408
74 4AA 0.9405
75 P3K 0.9405
76 3XX 0.9405
77 DIE 0.9403
78 51R 0.9401
79 4NC 0.9400
80 C2U 0.9399
81 MNM 0.9389
82 XAN 0.9386
83 BEN 0.9377
84 4SV 0.9376
85 URC 0.9376
86 AKH 0.9374
87 KFH 0.9371
88 293 0.9368
89 EVA 0.9367
90 DHK 0.9364
91 6PC 0.9364
92 BAM 0.9361
93 LGC 0.9360
94 I3A 0.9359
95 TH7 0.9353
96 HPA 0.9352
97 KJY 0.9349
98 PZA 0.9347
99 JZ3 0.9346
100 OXC 0.9345
101 PYG 0.9344
102 GTQ 0.9341
103 LYL 0.9337
104 NIO 0.9337
105 MAN 0.9335
106 3SK 0.9333
107 UNU 0.9329
108 SVD 0.9328
109 5M0 0.9327
110 DOB 0.9327
111 AHR 0.9322
112 SS1 0.9321
113 9MG 0.9321
114 1LN 0.9318
115 34D 0.9318
116 Q88 0.9317
117 XXR 0.9317
118 NK 0.9316
119 BTE 0.9315
120 J9T 0.9313
121 HZP 0.9313
122 DHB 0.9307
123 6M4 0.9306
124 LT2 0.9306
125 286 0.9305
126 4JT 0.9303
127 1LQ 0.9302
128 XX2 0.9302
129 5CU 0.9301
130 VK3 0.9299
131 BSX 0.9297
132 KOJ 0.9297
133 1WD 0.9296
134 DHQ 0.9296
135 1AB 0.9295
136 NMJ 0.9294
137 GAL 0.9292
138 WCE 0.9291
139 XYP 0.9288
140 3BZ 0.9286
141 TAG 0.9285
142 2CL 0.9283
143 FA0 0.9282
144 JZ4 0.9281
145 R8A 0.9281
146 1P3 0.9281
147 R9S 0.9281
148 PRY 0.9280
149 QSC 0.9280
150 T9G 0.9279
151 Q24 0.9279
152 JZ1 0.9278
153 AFR 0.9277
154 VNL 0.9276
155 KPL 0.9276
156 5RN 0.9272
157 FP1 0.9270
158 9TZ 0.9270
159 M58 0.9269
160 2CK 0.9269
161 BMA 0.9268
162 G6D 0.9267
163 GYE 0.9266
164 54G 0.9265
165 0P6 0.9265
166 PBC 0.9263
167 7WV 0.9262
168 8GC 0.9261
169 AGK 0.9258
170 WBU 0.9257
171 8S0 0.9256
172 ISE 0.9255
173 KBB 0.9254
174 SHG 0.9249
175 HH5 0.9249
176 XCZ 0.9248
177 JBE 0.9246
178 KYD 0.9243
179 NBZ 0.9243
180 LXC 0.9242
181 7VS 0.9242
182 ADE 0.9240
183 HMH 0.9240
184 CTS 0.9240
185 INO 0.9240
186 6CS 0.9239
187 ISZ 0.9238
188 GCS 0.9237
189 BHO 0.9237
190 NPO 0.9236
191 IFP 0.9236
192 FYU 0.9235
193 ASC 0.9234
194 JFJ 0.9233
195 B62 0.9232
196 ITN 0.9232
197 261 0.9231
198 ZXD 0.9231
199 SOE 0.9229
200 PA1 0.9229
201 PRF 0.9229
202 24W 0.9227
203 FBW 0.9224
204 URF 0.9224
205 7N0 0.9223
206 RIB 0.9223
207 TLA 0.9223
208 3AB 0.9219
209 15L 0.9214
210 R2B 0.9213
211 HBA 0.9213
212 I1N 0.9213
213 YSO 0.9211
214 7B4 0.9211
215 D3M 0.9210
216 G3F 0.9210
217 RM1 0.9210
218 BNS 0.9209
219 B53 0.9206
220 ADA 0.9205
221 ICO 0.9205
222 MYJ 0.9205
223 5MK 0.9204
224 CRN 0.9203
225 PAB 0.9201
226 GTR 0.9199
227 TEP 0.9198
228 PHB 0.9196
229 2AL 0.9195
230 93K 0.9194
231 DQU 0.9194
232 5WX 0.9193
233 RPQ 0.9191
234 3PF 0.9190
235 INS 0.9189
236 AW5 0.9188
237 X05 0.9187
238 BDF 0.9185
239 GIF 0.9185
240 BZ3 0.9179
241 FA1 0.9177
242 4NG 0.9177
243 C2A 0.9176
244 42C 0.9174
245 HLZ 0.9174
246 GLA 0.9172
247 2ZV 0.9172
248 UEG 0.9171
249 P9P 0.9170
250 L99 0.9170
251 SHA 0.9167
252 1U6 0.9167
253 FCR 0.9167
254 HQD 0.9167
255 3MB 0.9167
256 HBX 0.9166
257 EV0 0.9165
258 5NU 0.9164
259 MZB 0.9164
260 B57 0.9163
261 XM0 0.9162
262 UNC 0.9162
263 RSO 0.9162
264 PFB 0.9162
265 TTL 0.9162
266 CTL 0.9162
267 XYS 0.9161
268 AZA 0.9161
269 J9W 0.9161
270 5WY 0.9160
271 ISD 0.9159
272 GLF 0.9159
273 GIO 0.9159
274 TTY 0.9158
275 NIZ 0.9157
276 82I 0.9156
277 4M0 0.9156
278 9TW 0.9156
279 60P 0.9155
280 1PT 0.9155
281 948 0.9152
282 GCV 0.9151
283 O2A 0.9150
284 2H5 0.9150
285 OHP 0.9150
286 GOG 0.9149
287 KBG 0.9149
288 8EZ 0.9148
289 E7Z 0.9148
290 64K 0.9147
291 PFL 0.9147
292 FBM 0.9146
293 SX1 0.9145
294 2HO 0.9142
295 5RO 0.9142
296 260 0.9141
297 5AC 0.9140
298 GAF 0.9139
299 2XX 0.9139
300 MJ2 0.9138
301 FUL 0.9138
302 5HN 0.9137
303 3WA 0.9137
304 1P8 0.9137
305 SVN 0.9135
306 KIB 0.9134
307 CXF 0.9134
308 OVM 0.9133
309 UYA 0.9133
310 SKM 0.9132
311 SS2 0.9132
312 NTM 0.9132
313 141 0.9131
314 OAA 0.9131
315 SYG 0.9130
316 GBD 0.9130
317 7ZE 0.9130
318 1F1 0.9127
319 PZI 0.9126
320 IGA 0.9125
321 BHA 0.9124
322 OW4 0.9124
323 4CS 0.9123
324 FA3 0.9122
325 L3Q 0.9122
326 X6X 0.9121
327 CFI 0.9121
328 32X 0.9121
329 ARB 0.9120
330 ARA 0.9120
331 7HP 0.9120
332 V55 0.9120
333 HNQ 0.9119
334 PXL 0.9119
335 X0V 0.9119
336 AC0 0.9118
337 GIV 0.9118
338 GXL 0.9117
339 FAN 0.9117
340 2FG 0.9116
341 ASN 0.9116
342 3V4 0.9115
343 069 0.9114
344 N5J 0.9113
345 4ME 0.9111
346 G3P 0.9109
347 2LP 0.9109
348 M1H 0.9109
349 IDM 0.9107
350 2EC 0.9106
351 GJZ 0.9106
352 INE 0.9106
353 3ID 0.9105
354 KIA 0.9104
355 IPB 0.9104
356 329 0.9104
357 A13 0.9103
358 SWA 0.9103
359 GAG 0.9103
360 7HQ 0.9101
361 F9P 0.9100
362 7NI 0.9099
363 AZG 0.9099
364 40E 0.9099
365 GDE 0.9099
366 290 0.9098
367 9PY 0.9098
368 3MG 0.9097
369 2K4 0.9096
370 0MK 0.9096
371 ES2 0.9096
372 5DI 0.9095
373 45L 0.9094
374 ZZ3 0.9093
375 ADZ 0.9093
376 44W 0.9092
377 NDM 0.9091
378 6AP 0.9090
379 MXN 0.9090
380 DQN 0.9090
381 SYN 0.9089
382 5SG 0.9088
383 5IQ 0.9088
384 FBU 0.9088
385 EYK 0.9088
386 4XV 0.9087
387 6ME 0.9087
388 PMB 0.9085
389 HY1 0.9084
390 8H8 0.9084
391 FRU 0.9083
392 Z82 0.9083
393 HA7 0.9082
394 95Z 0.9082
395 9KH 0.9082
396 ALL 0.9081
397 3Z7 0.9081
398 PAF 0.9081
399 3CE 0.9080
400 4VP 0.9079
401 4HC 0.9079
402 EKZ 0.9078
403 SNE 0.9078
404 1LM 0.9077
405 HMU 0.9077
406 AMC 0.9076
407 2CM 0.9076
408 ABN 0.9076
409 1Y6 0.9076
410 1GN 0.9075
411 F60 0.9075
412 1NP 0.9075
413 LMR 0.9074
414 JBH 0.9072
415 JPZ 0.9072
416 1XM 0.9072
417 TM4 0.9071
418 HQY 0.9071
419 94B 0.9070
420 BOA 0.9068
421 4YS 0.9068
422 1SQ 0.9067
423 HYA 0.9066
424 JTH 0.9066
425 0W8 0.9066
426 ZWZ 0.9065
427 ES1 0.9065
428 5Q0 0.9065
429 6AI 0.9065
430 BNT 0.9065
431 O72 0.9064
432 8WO 0.9063
433 ZB1 0.9062
434 URA 0.9061
435 24B 0.9060
436 5MB 0.9058
437 IT2 0.9057
438 5H1 0.9056
439 2AS 0.9055
440 7MH 0.9055
441 PXM 0.9054
442 PEL 0.9054
443 ASP 0.9054
444 RIP 0.9054
445 KT7 0.9053
446 VGL 0.9051
447 QSB 0.9051
448 44V 0.9051
449 3PG 0.9050
450 A7W 0.9050
451 6GU 0.9050
452 AZ8 0.9050
453 RBL 0.9049
454 RNS 0.9049
455 SEJ 0.9049
456 DBX 0.9048
457 H42 0.9048
458 271 0.9046
459 MBD 0.9046
460 6MH 0.9045
461 6M9 0.9044
462 IHB 0.9044
463 2A7 0.9043
464 XXP 0.9043
465 CHB 0.9043
466 PEA 0.9042
467 RM4 0.9042
468 PE0 0.9041
469 GLT 0.9040
470 NEQ 0.9040
471 TAR 0.9040
472 MZW 0.9040
473 5XC 0.9040
474 14J 0.9039
475 OVP 0.9038
476 AC6 0.9036
477 XLS 0.9035
478 QY9 0.9035
479 4XR 0.9035
480 N8P 0.9035
481 NDH 0.9035
482 449 0.9035
483 DUB 0.9034
484 NPY 0.9034
485 QUZ 0.9034
486 M1Q 0.9033
487 FUC 0.9033
488 YIO 0.9032
489 F1A 0.9032
490 AS3 0.9030
491 EDR 0.9030
492 MNN 0.9030
493 HBD 0.9027
494 GZL 0.9026
495 23W 0.9026
496 PBE 0.9025
497 4MA 0.9025
498 BRT 0.9024
499 2ZQ 0.9024
500 CRS 0.9024
501 AKG 0.9022
502 MT5 0.9021
503 COU 0.9020
504 X09 0.9020
505 DX4 0.9019
506 7MU 0.9019
507 PAC 0.9018
508 ES0 0.9018
509 2ZM 0.9018
510 LSA 0.9018
511 HLR 0.9017
512 5QX 0.9016
513 MMA 0.9014
514 0RW 0.9013
515 QSH 0.9013
516 5NI 0.9012
517 FB2 0.9012
518 3MH 0.9011
519 G4D 0.9011
520 PDC 0.9011
521 ILE 0.9011
522 RAT 0.9010
523 DAS 0.9010
524 TFB 0.9010
525 R8V 0.9009
526 F31 0.9008
527 LDP 0.9007
528 JAE 0.9007
529 FPI 0.9007
530 K17 0.9007
531 GOO 0.9006
532 MEW 0.9006
533 MUC 0.9005
534 M0Q 0.9005
535 1P7 0.9004
536 2CQ 0.9004
537 JBQ 0.9003
538 270 0.9003
539 ZZT 0.9003
540 I1E 0.9002
541 OMD 0.9002
542 HGQ 0.9000
543 5QY 0.8999
544 FCB 0.8999
545 AX7 0.8997
546 2LY 0.8996
547 DGJ 0.8996
548 4P5 0.8996
549 9EW 0.8995
550 1WG 0.8995
551 KP6 0.8994
552 R8S 0.8994
553 B24 0.8994
554 0HO 0.8994
555 92K 0.8993
556 M6N 0.8993
557 QIC 0.8993
558 5GU 0.8992
559 FEH 0.8991
560 FCA 0.8991
561 T6C 0.8989
562 NSP 0.8988
563 EQT 0.8988
564 SYA 0.8987
565 OXQ 0.8987
566 QWN 0.8987
567 OCH 0.8987
568 FFP 0.8986
569 ES9 0.8986
570 MBG 0.8986
571 OA3 0.8985
572 F0J 0.8985
573 4FH 0.8984
574 4PW 0.8984
575 3Z8 0.8984
576 2FY 0.8982
577 B55 0.8981
578 10L 0.8978
579 8WT 0.8978
580 XYL 0.8977
581 RB5 0.8977
582 CWM 0.8977
583 GV9 0.8977
584 03V 0.8977
585 FUF 0.8976
586 H76 0.8976
587 7A8 0.8974
588 DIN 0.8974
589 MS9 0.8974
590 FDB 0.8974
591 UFV 0.8974
592 MWP 0.8973
593 BCU 0.8972
594 5OB 0.8972
595 MFB 0.8972
596 F5B 0.8971
597 PQ0 0.8970
598 9HX 0.8969
599 173 0.8969
600 DBJ 0.8968
601 S76 0.8967
602 QBK 0.8967
603 AJ2 0.8967
604 3NY 0.8967
605 AQO 0.8966
606 PRZ 0.8966
607 1XN 0.8965
608 97T 0.8964
609 LZM 0.8964
610 PHT 0.8963
611 94N 0.8962
612 PHU 0.8962
613 GMN 0.8961
614 NVU 0.8961
615 2MY 0.8960
616 FGZ 0.8960
617 M5K 0.8960
618 LRH 0.8959
619 MCT 0.8959
620 2MI 0.8959
621 717 0.8959
622 RSF 0.8959
623 KJH 0.8958
624 M4T 0.8958
625 26D 0.8958
626 TFU 0.8957
627 N3W 0.8956
628 MRW 0.8955
629 LEU 0.8954
630 7WG 0.8953
631 PYJ 0.8953
632 CFP 0.8952
633 0CU 0.8952
634 XBZ 0.8951
635 4ZE 0.8951
636 6UA 0.8951
637 4YO 0.8951
638 FH2 0.8950
639 MWM 0.8950
640 7W1 0.8950
641 MR1 0.8950
642 12Q 0.8948
643 NBE 0.8947
644 O7U 0.8946
645 J9Q 0.8945
646 7WA 0.8944
647 IPZ 0.8944
648 6NT 0.8943
649 KJU 0.8943
650 149 0.8942
651 APY 0.8942
652 4XH 0.8941
653 1DJ 0.8941
654 M1E 0.8941
655 289 0.8940
656 HDH 0.8940
657 KKN 0.8940
658 TZE 0.8940
659 2PG 0.8940
660 KTA 0.8939
661 CEE 0.8939
662 4HM 0.8939
663 6KX 0.8939
664 3BU 0.8939
665 ISN 0.8938
666 L7T 0.8938
667 2AC 0.8936
668 ROR 0.8935
669 BE7 0.8935
670 DEN 0.8935
671 GLL 0.8935
672 150 0.8934
673 TSU 0.8933
674 FDK 0.8931
675 6OT 0.8931
676 FQI 0.8931
677 GCW 0.8931
678 ABI 0.8931
679 Z6J 0.8929
680 34A 0.8929
681 DHS 0.8929
682 XUL 0.8928
683 680 0.8928
684 ES5 0.8927
685 9RW 0.8927
686 HH8 0.8927
687 HQT 0.8927
688 23J 0.8924
689 LNR 0.8924
690 2AQ 0.8924
691 TPA 0.8924
692 EUG 0.8924
693 SW7 0.8924
694 XX3 0.8923
695 2C9 0.8922
696 OK7 0.8920
697 3SL 0.8919
698 DA4 0.8919
699 M0W 0.8919
700 N7P 0.8918
701 4Z4 0.8915
702 0HN 0.8915
703 KDF 0.8915
704 ADK 0.8914
705 PQK 0.8914
706 RMN 0.8913
707 IOM 0.8913
708 3HP 0.8912
709 D48 0.8912
710 G3E 0.8910
711 JB5 0.8909
712 JZ9 0.8909
713 3ZQ 0.8909
714 DQA 0.8907
715 4A3 0.8907
716 0R1 0.8907
717 QOS 0.8906
718 A1U 0.8906
719 PRS 0.8905
720 MO8 0.8904
721 JUG 0.8903
722 HX3 0.8903
723 OEM 0.8902
724 EXO 0.8902
725 6JN 0.8901
726 MLT 0.8901
727 TEO 0.8901
728 FHB 0.8901
729 VOH 0.8901
730 AZ9 0.8901
731 3FA 0.8900
732 8XQ 0.8900
733 TM7 0.8898
734 IF7 0.8897
735 4ZC 0.8897
736 8GK 0.8897
737 8NY 0.8896
738 B2J 0.8895
739 PRO 0.8895
740 EDG 0.8894
741 CLW 0.8894
742 42A 0.8894
743 4XS 0.8894
744 AOS 0.8891
745 ABE 0.8890
746 WOO 0.8890
747 ABV 0.8889
748 LZ1 0.8889
749 NNO 0.8889
750 4TU 0.8889
751 FLM 0.8888
752 8IG 0.8888
753 P92 0.8887
754 3MC 0.8887
755 M2H 0.8886
756 DFU 0.8886
757 0CT 0.8885
758 36R 0.8884
759 JLZ 0.8884
760 5WV 0.8884
761 NXA 0.8883
762 3MA 0.8883
763 MSN 0.8882
764 4SX 0.8882
765 N2Z 0.8879
766 LKA 0.8879
767 GT0 0.8879
768 DS0 0.8878
769 BZF 0.8878
770 52C 0.8877
771 CIZ 0.8877
772 3DO 0.8875
773 4HO 0.8874
774 0LH 0.8874
775 FBA 0.8874
776 N2I 0.8874
777 XIY 0.8873
778 2YU 0.8871
779 M2K 0.8871
780 4FS 0.8871
781 T2C 0.8870
782 SF9 0.8869
783 1DW 0.8867
784 TIU 0.8867
785 A29 0.8866
786 ODO 0.8865
787 GLU 0.8865
788 14O 0.8864
789 TDR 0.8864
790 SAN 0.8864
791 1XX 0.8863
792 4CL 0.8863
793 LPK 0.8863
794 42J 0.8862
795 4JJ 0.8862
796 QXW 0.8861
797 MVL 0.8861
798 7ME 0.8858
799 JIF 0.8858
800 51F 0.8858
801 HIO 0.8857
802 URS 0.8857
803 PYQ 0.8857
804 39A 0.8856
805 2MP 0.8854
806 HQJ 0.8854
807 ES7 0.8853
808 G1O 0.8852
809 HQ9 0.8851
810 NQ 0.8851
811 ICF 0.8851
812 PEP 0.8851
813 SR1 0.8850
814 KLW 0.8850
815 Z5P 0.8849
816 NCT 0.8849
817 3HM 0.8848
818 IV2 0.8848
819 P72 0.8848
820 NTZ 0.8846
821 PYF 0.8845
822 HT4 0.8844
823 AL0 0.8844
824 PBZ 0.8844
825 MZG 0.8843
826 284 0.8841
827 0V5 0.8841
828 ZBT 0.8840
829 3AL 0.8839
830 67N 0.8839
831 PM6 0.8836
832 2MN 0.8835
833 FPY 0.8834
834 ARW 0.8833
835 RUU 0.8833
836 2D0 0.8832
837 EHM 0.8832
838 0TR 0.8831
839 PD2 0.8831
840 XSP 0.8830
841 1MR 0.8828
842 A2F 0.8828
843 SMV 0.8828
844 NTN 0.8828
845 7W4 0.8827
846 9R5 0.8826
847 DMD 0.8826
848 GRO 0.8825
849 XQ0 0.8825
850 7VJ 0.8824
851 NID 0.8823
852 RXA 0.8820
853 KUF 0.8820
854 BP9 0.8820
855 KGK 0.8819
856 ICP 0.8817
857 XYD 0.8817
858 3A9 0.8817
859 A09 0.8815
860 JBN 0.8815
861 SAF 0.8812
862 SEP 0.8810
863 9CL 0.8809
864 IDH 0.8808
865 JAW 0.8808
866 SXS 0.8807
867 5VM 0.8806
868 JXW 0.8805
869 THE 0.8804
870 1MC 0.8804
871 P84 0.8802
872 8OZ 0.8802
873 7D2 0.8801
874 FBB 0.8801
875 GIM 0.8800
876 SOR 0.8799
877 3CU 0.8799
878 PCA 0.8799
879 JZ5 0.8798
880 7CZ 0.8798
881 5MI 0.8798
882 YRL 0.8796
883 QPR 0.8796
884 TH0 0.8796
885 6NI 0.8796
886 4J8 0.8795
887 92P 0.8793
888 BR9 0.8793
889 2DR 0.8793
890 C2Y 0.8792
891 B0D 0.8789
892 4FA 0.8789
893 TSS 0.8789
894 TBP 0.8789
895 VGD 0.8788
896 8G0 0.8787
897 HFB 0.8787
898 GYP 0.8787
899 R1X 0.8787
900 4JL 0.8786
901 SYV 0.8785
902 EA1 0.8784
903 FUB 0.8782
904 QX2 0.8781
905 57O 0.8780
906 JXN 0.8778
907 XHP 0.8778
908 27Y 0.8777
909 SMN 0.8777
910 PYC 0.8777
911 5JC 0.8776
912 12M 0.8775
913 AAS 0.8775
914 JKZ 0.8775
915 CIT 0.8773
916 ICB 0.8773
917 II6 0.8772
918 HZQ 0.8769
919 3GQ 0.8767
920 HTP 0.8765
921 K7M 0.8764
922 FBS 0.8760
923 K2T 0.8760
924 AEF 0.8760
925 IPM 0.8759
926 MWJ 0.8759
927 HYP 0.8758
928 5UC 0.8757
929 J5I 0.8757
930 VXX 0.8756
931 12B 0.8753
932 AH8 0.8753
933 4JP 0.8750
934 ENL 0.8749
935 JFD 0.8749
936 AUD 0.8747
937 TMT 0.8747
938 209 0.8747
939 GOX 0.8747
940 QWW 0.8746
941 6RQ 0.8746
942 SE2 0.8745
943 2TQ 0.8745
944 FLC 0.8745
945 PEZ 0.8743
946 BZI 0.8743
947 B60 0.8743
948 PKU 0.8743
949 IND 0.8741
950 5B1 0.8740
951 I4B 0.8736
952 8EW 0.8736
953 275 0.8736
954 F4Z 0.8736
955 826 0.8734
956 C2B 0.8733
957 280 0.8732
958 GLN 0.8731
959 9X7 0.8730
960 EJZ 0.8730
961 BTY 0.8730
962 8CM 0.8729
963 APZ 0.8727
964 RCO 0.8725
965 JYD 0.8724
966 5HY 0.8724
967 M1A 0.8724
968 MAK 0.8723
969 282 0.8719
970 YHO 0.8718
971 DZX 0.8718
972 MFU 0.8718
973 0N7 0.8715
974 RP7 0.8714
975 DIG 0.8714
976 11S 0.8713
977 2BG 0.8713
978 DMV 0.8713
979 DRL 0.8713
980 RBJ 0.8712
981 4P0 0.8712
982 MHK 0.8711
983 DYA 0.8711
984 AMG 0.8711
985 GTZ 0.8711
986 XXG 0.8710
987 EPR 0.8710
988 0JD 0.8709
989 MVN 0.8709
990 E5X 0.8708
991 BCF 0.8706
992 PBA 0.8706
993 CWS 0.8705
994 TMZ 0.8705
995 JB8 0.8705
996 37T 0.8705
997 OHG 0.8703
998 32O 0.8701
999 SDD 0.8701
1000 SF6 0.8699
1001 BBF 0.8699
1002 BCP 0.8698
1003 TBS 0.8698
1004 GLO 0.8696
1005 2MH 0.8696
1006 JDN 0.8695
1007 OTW 0.8694
1008 GVH 0.8690
1009 PSJ 0.8688
1010 BR8 0.8686
1011 1SA 0.8686
1012 2KA 0.8686
1013 TT4 0.8684
1014 0TU 0.8682
1015 ECE 0.8681
1016 YQA 0.8680
1017 LG3 0.8680
1018 6FZ 0.8679
1019 DNF 0.8679
1020 174 0.8678
1021 DEE 0.8678
1022 JND 0.8675
1023 1DV 0.8675
1024 FBJ 0.8674
1025 SLC 0.8674
1026 1DQ 0.8674
1027 3R6 0.8672
1028 JXZ 0.8671
1029 MQN 0.8671
1030 4M4 0.8670
1031 AMS 0.8669
1032 YH7 0.8668
1033 SPA 0.8667
1034 1XA 0.8666
1035 1X7 0.8666
1036 MPI 0.8666
1037 4JO 0.8665
1038 MAQ 0.8665
1039 EMZ 0.8664
1040 QM1 0.8662
1041 R9Y 0.8662
1042 AEZ 0.8662
1043 15N 0.8661
1044 IAC 0.8660
1045 4JU 0.8660
1046 BEA 0.8659
1047 YTB 0.8659
1048 4ZA 0.8659
1049 IBF 0.8658
1050 H4N 0.8656
1051 XBT 0.8656
1052 5WU 0.8654
1053 3CH 0.8654
1054 K3Q 0.8654
1055 0F9 0.8653
1056 JZ2 0.8653
1057 REL 0.8653
1058 NCD 0.8652
1059 OTD 0.8651
1060 2M5 0.8651
1061 3C4 0.8649
1062 ICC 0.8646
1063 2HU 0.8642
1064 QMP 0.8642
1065 6LW 0.8642
1066 1WC 0.8642
1067 9KT 0.8638
1068 BVF 0.8638
1069 GVG 0.8637
1070 F3B 0.8636
1071 H3M 0.8634
1072 DC5 0.8634
1073 35C 0.8632
1074 HHH 0.8630
1075 E35 0.8627
1076 5MH 0.8626
1077 FA6 0.8625
1078 Y8I 0.8623
1079 LI6 0.8623
1080 IUR 0.8621
1081 NAG 0.8620
1082 2GS 0.8620
1083 LAO 0.8620
1084 L5V 0.8618
1085 4WL 0.8612
1086 FHN 0.8610
1087 DUC 0.8610
1088 ESP 0.8608
1089 BEW 0.8607
1090 DHY 0.8606
1091 GZQ 0.8603
1092 THR 0.8601
1093 SPV 0.8600
1094 NFQ 0.8597
1095 HPY 0.8590
1096 7WR 0.8589
1097 AX3 0.8587
1098 2CZ 0.8585
1099 AMH 0.8584
1100 IMR 0.8584
1101 0GZ 0.8584
1102 2CH 0.8582
1103 TZL 0.8581
1104 GTL 0.8578
1105 G2H 0.8578
1106 GJP 0.8578
1107 HSE 0.8568
1108 URP 0.8566
1109 EGR 0.8566
1110 6X8 0.8560
1111 JA8 0.8555
1112 AJV 0.8551
1113 4HP 0.8535
1114 J1Z 0.8529
1115 CGB 0.8519
1116 LFR 0.8518
1117 FK8 0.8518
1118 URQ 0.8509
1119 43M 0.8508
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: 21
This union binding pocket(no: 1) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6NCZ FYJ 41.0866
2 6NCZ FYJ 41.0866
3 6NCZ FYJ 41.0866
4 6NCZ FYJ 41.0866
5 6NCZ FYJ 41.0866
6 6NCZ FYJ 41.0866
7 6NCZ FYJ 41.0866
8 6NCZ FYJ 41.0866
9 6NCZ FYJ 41.0866
10 6NCZ FYJ 41.0866
11 6NCZ FYJ 41.0866
12 6NCZ FYJ 41.0866
13 6D50 GCB 42.4448
14 6D50 GCB 42.4448
15 6D6W GCU 44.3869
16 6D6W GCU 44.3869
17 6D6W GCU 44.3869
18 6D6W GCU 44.3869
19 6D6W GCU 44.3869
20 6D6W GCU 44.3869
21 6D6W GCU 44.3869
Pocket No.: 2; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: 21
This union binding pocket(no: 3) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6NCZ FYJ 41.0866
2 6NCZ FYJ 41.0866
3 6NCZ FYJ 41.0866
4 6NCZ FYJ 41.0866
5 6NCZ FYJ 41.0866
6 6NCZ FYJ 41.0866
7 6NCZ FYJ 41.0866
8 6NCZ FYJ 41.0866
9 6NCZ FYJ 41.0866
10 6NCZ FYJ 41.0866
11 6NCZ FYJ 41.0866
12 6NCZ FYJ 41.0866
13 6D50 GCB 42.4448
14 6D50 GCB 42.4448
15 6D6W GCU 44.3869
16 6D6W GCU 44.3869
17 6D6W GCU 44.3869
18 6D6W GCU 44.3869
19 6D6W GCU 44.3869
20 6D6W GCU 44.3869
21 6D6W GCU 44.3869
Pocket No.: 4; Query (leader) PDB : 6JZ2; Ligand: SJ5; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 6jz2.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback