Receptor
PDB id Resolution Class Description Source Keywords
5JAN 2.12 Å EC: 3.1.1.47 EXPLOITATION OF A NOVEL BINDING POCKET IN HUMAN LIPOPROTEIN- PHOSPHOLIPASE A2 (LP-PLA2) DISCOVERED THROUGH X-F RAGMENT SCREENING HOMO SAPIENS PHOSPHOLIPASE LIPID METABOLISM HYDROLASE
Ref.: EXPLOITATION OF A NOVEL BINDING POCKET IN HUMAN LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 (LP-PLA2) D THROUGH X-RAY FRAGMENT SCREENING. J.MED.CHEM. V. 59 5356 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:501;
A:502;
 Invalid;
Invalid;
 none;
none;
 submit data
35.453 Cl [Cl-]
6HP A:504;
 Valid;
 none;
 submit data
212.246 C10 H16 N2 O3 CC(C)...
CA A:503;
 Part of Protein;
 none;
 submit data
40.078 Ca [Ca+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LP1 1.91 Å EC: 3.1.1.47 CRYSTAL STRUCTURE OF HUMAN LIPOPROTEIN-ASSOCIATED PHOSPHOLIP COMPLEX WITH A [1.1.1]BICYCLOPENTANE-CONTAINING INHIBITOR AR ESOLUTION. HOMO SAPIENS PLASMA PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE SECRETED ALPHA/BETA-HYDROLASE-FOLD LDL-BOUND; LIPOPROTEIN ASSOCIATEPHOSPHOLIPASE A2 LP-PLA2 GROUP VIIA PLA2 GLYCOPROTEIN HLIPID DEGRADATION POLYMORPHISM SECRETED HYDROLASE-HYDROLINHIBITOR COMPLEX
Ref.: INVESTIGATION OF A BICYCLO[1.1.1]PENTANE AS A PHENY REPLACEMENT WITHIN AN LPPLA2 INHIBITOR. ACS MED CHEM LETT V. 8 43 2017
Members (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5YE8 ic50 ~ 1 mM 8U3 C7 H7 F2 N O2 S CS(=O)(=O)....
2 5JAH - 6HQ C6 H10 N2 O2 CC1(C(=O)N....
3 5JAP ic50 = 0.23 uM 6HZ C19 H19 N O Cc1ccccc1c....
4 5LZ4 Kd = 2 uM 7BW C15 H17 F N2 O2 CC1(CC(=O)....
5 5JAL Kd = 980 uM 6HO C11 H10 F N O c1cc(cc(c1....
6 5YE9 ic50 = 355 nM 8U6 C25 H19 N3 O4 S CC(=O)Nc1c....
7 5JAN - 6HP C10 H16 N2 O3 CC(C)COC1=....
8 5JAS ic50 = 1.7 uM 6HW C17 H16 N2 S Cc1ccccc1c....
9 5LZ9 ic50 = 0.12 uM 7BR C19 H23 F N2 O4 S CC1(CCS(=O....
10 5LZ2 ic50 ~ 1 mM 7BX C10 H10 N2 O2 S c1cc(cc(c1....
11 5YE7 ic50 = 3431 nM 8U0 C24 H20 N2 O4 S CC(=O)Nc1c....
12 5JAT ic50 = 0.23 uM 6HR C20 H22 N2 O S Cc1ccccc1c....
13 5LZ8 ic50 = 0.98 uM 7BP C17 H21 F N2 O2 CC(C)(C)[C....
14 5JAU ic50 = 0.0014 uM 6HU C23 H30 N4 O3 Cc1ccccc1c....
15 5LZ7 Kd = 0.53 uM 7BK C20 H19 F N2 O2 C[C@@]1(CC....
16 5YEA ic50 = 5 nM 8U9 C21 H12 Cl F3 N2 O5 S c1cc(ccc1C....
17 5LYY ic50 = 14 uM 7BJ C16 H19 F N2 O3 c1cc(ccc1O....
18 5LP1 ic50 = 0.398 nM 71H C35 H38 F4 N4 O2 S CCN(CC)CCN....
19 5JAR ic50 = 2 uM 6HV C18 H15 N O S Cc1ccccc1c....
20 5LZ5 Kd = 0.45 uM 7K4 C20 H19 F N2 O2 C[C@]1(CC(....
21 5I8P Kd = 0.000000064 M VQ7 C23 H19 Cl F5 N3 O5 S CN1C(=CC(=....
22 5JAD Kd = 3.4 mM FB2 C6 H7 N O2 S c1ccc(cc1)....
23 5JAO - 6HX C13 H12 Cl N Cc1ccc(cc1....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5YE8 ic50 ~ 1 mM 8U3 C7 H7 F2 N O2 S CS(=O)(=O)....
2 5JAH - 6HQ C6 H10 N2 O2 CC1(C(=O)N....
3 5JAP ic50 = 0.23 uM 6HZ C19 H19 N O Cc1ccccc1c....
4 5LZ4 Kd = 2 uM 7BW C15 H17 F N2 O2 CC1(CC(=O)....
5 5JAL Kd = 980 uM 6HO C11 H10 F N O c1cc(cc(c1....
6 5YE9 ic50 = 355 nM 8U6 C25 H19 N3 O4 S CC(=O)Nc1c....
7 5JAN - 6HP C10 H16 N2 O3 CC(C)COC1=....
8 5JAS ic50 = 1.7 uM 6HW C17 H16 N2 S Cc1ccccc1c....
9 5LZ9 ic50 = 0.12 uM 7BR C19 H23 F N2 O4 S CC1(CCS(=O....
10 5LZ2 ic50 ~ 1 mM 7BX C10 H10 N2 O2 S c1cc(cc(c1....
11 5YE7 ic50 = 3431 nM 8U0 C24 H20 N2 O4 S CC(=O)Nc1c....
12 5JAT ic50 = 0.23 uM 6HR C20 H22 N2 O S Cc1ccccc1c....
13 5LZ8 ic50 = 0.98 uM 7BP C17 H21 F N2 O2 CC(C)(C)[C....
14 5JAU ic50 = 0.0014 uM 6HU C23 H30 N4 O3 Cc1ccccc1c....
15 5LZ7 Kd = 0.53 uM 7BK C20 H19 F N2 O2 C[C@@]1(CC....
16 5YEA ic50 = 5 nM 8U9 C21 H12 Cl F3 N2 O5 S c1cc(ccc1C....
17 5LYY ic50 = 14 uM 7BJ C16 H19 F N2 O3 c1cc(ccc1O....
18 5LP1 ic50 = 0.398 nM 71H C35 H38 F4 N4 O2 S CCN(CC)CCN....
19 5JAR ic50 = 2 uM 6HV C18 H15 N O S Cc1ccccc1c....
20 5LZ5 Kd = 0.45 uM 7K4 C20 H19 F N2 O2 C[C@]1(CC(....
21 5I8P Kd = 0.000000064 M VQ7 C23 H19 Cl F5 N3 O5 S CN1C(=CC(=....
22 5JAD Kd = 3.4 mM FB2 C6 H7 N O2 S c1ccc(cc1)....
23 5JAO - 6HX C13 H12 Cl N Cc1ccc(cc1....
50% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 5YE8 ic50 ~ 1 mM 8U3 C7 H7 F2 N O2 S CS(=O)(=O)....
2 5JAH - 6HQ C6 H10 N2 O2 CC1(C(=O)N....
3 5JAP ic50 = 0.23 uM 6HZ C19 H19 N O Cc1ccccc1c....
4 5LZ4 Kd = 2 uM 7BW C15 H17 F N2 O2 CC1(CC(=O)....
5 5JAL Kd = 980 uM 6HO C11 H10 F N O c1cc(cc(c1....
6 5YE9 ic50 = 355 nM 8U6 C25 H19 N3 O4 S CC(=O)Nc1c....
7 5JAN - 6HP C10 H16 N2 O3 CC(C)COC1=....
8 5JAS ic50 = 1.7 uM 6HW C17 H16 N2 S Cc1ccccc1c....
9 5LZ9 ic50 = 0.12 uM 7BR C19 H23 F N2 O4 S CC1(CCS(=O....
10 5LZ2 ic50 ~ 1 mM 7BX C10 H10 N2 O2 S c1cc(cc(c1....
11 5YE7 ic50 = 3431 nM 8U0 C24 H20 N2 O4 S CC(=O)Nc1c....
12 5JAT ic50 = 0.23 uM 6HR C20 H22 N2 O S Cc1ccccc1c....
13 5LZ8 ic50 = 0.98 uM 7BP C17 H21 F N2 O2 CC(C)(C)[C....
14 5JAU ic50 = 0.0014 uM 6HU C23 H30 N4 O3 Cc1ccccc1c....
15 5LZ7 Kd = 0.53 uM 7BK C20 H19 F N2 O2 C[C@@]1(CC....
16 5YEA ic50 = 5 nM 8U9 C21 H12 Cl F3 N2 O5 S c1cc(ccc1C....
17 5LYY ic50 = 14 uM 7BJ C16 H19 F N2 O3 c1cc(ccc1O....
18 5LP1 ic50 = 0.398 nM 71H C35 H38 F4 N4 O2 S CCN(CC)CCN....
19 5JAR ic50 = 2 uM 6HV C18 H15 N O S Cc1ccccc1c....
20 5LZ5 Kd = 0.45 uM 7K4 C20 H19 F N2 O2 C[C@]1(CC(....
21 5I8P Kd = 0.000000064 M VQ7 C23 H19 Cl F5 N3 O5 S CN1C(=CC(=....
22 5JAD Kd = 3.4 mM FB2 C6 H7 N O2 S c1ccc(cc1)....
23 5JAO - 6HX C13 H12 Cl N Cc1ccc(cc1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 6HP; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 6HP 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 6HP; Similar ligands found: 601
No: Ligand Similarity coefficient
1 F5C 0.9637
2 G6P 0.9605
3 4R1 0.9505
4 L21 0.9435
5 BG6 0.9423
6 PLR 0.9411
7 GLP 0.9407
8 M6P 0.9385
9 PLP 0.9380
10 NBV 0.9359
11 SBK 0.9353
12 FER 0.9353
13 IPD 0.9341
14 F52 0.9337
15 NPL 0.9336
16 AMR 0.9333
17 G1P 0.9330
18 PMP 0.9327
19 HPT 0.9323
20 LIP 0.9322
21 5OF 0.9318
22 DHC 0.9311
23 9F8 0.9296
24 ZIP 0.9284
25 1QV 0.9281
26 ARP 0.9278
27 9BF 0.9277
28 PXP 0.9264
29 IOP 0.9255
30 NQH 0.9250
31 QIF 0.9248
32 EYM 0.9242
33 K3Q 0.9237
34 SG2 0.9237
35 EYA 0.9235
36 57O 0.9232
37 NBG 0.9231
38 I2E 0.9220
39 STT 0.9214
40 UQ1 0.9207
41 GXG 0.9205
42 3LJ 0.9203
43 TRP 0.9188
44 O2Y 0.9188
45 BDI 0.9185
46 V1T 0.9183
47 IAC 0.9181
48 X04 0.9178
49 CR1 0.9163
50 BGP 0.9154
51 PZP 0.9148
52 PLP PMP 0.9148
53 XFE 0.9146
54 OX2 0.9145
55 NPA 0.9145
56 C9E 0.9142
57 5V7 0.9137
58 3IL 0.9137
59 NLA 0.9127
60 2LT 0.9127
61 FWD 0.9127
62 AC2 0.9126
63 PVQ 0.9125
64 BY5 0.9117
65 EGR 0.9116
66 H35 0.9112
67 TSR 0.9111
68 68A 0.9106
69 FF2 0.9102
70 PVK 0.9100
71 5WN 0.9098
72 KG1 0.9096
73 NIY 0.9089
74 EXL 0.9089
75 B23 0.9089
76 IOS 0.9086
77 3RI 0.9086
78 ALN 0.9086
79 RGG 0.9086
80 NFM 0.9086
81 1QP 0.9083
82 CPW 0.9081
83 GI1 0.9080
84 4GP 0.9080
85 TSS 0.9078
86 C9M 0.9075
87 GJK 0.9074
88 M6D 0.9073
89 2HC 0.9073
90 SXX 0.9073
91 8W9 0.9069
92 NAG 0.9069
93 CGW 0.9066
94 EYY 0.9058
95 IBM 0.9057
96 OUB 0.9055
97 96Z 0.9055
98 YTX 0.9054
99 QMS 0.9054
100 5WT 0.9053
101 ZEA 0.9053
102 8U3 0.9051
103 GO8 0.9051
104 9E3 0.9051
105 DHY 0.9047
106 I4D 0.9042
107 6Q3 0.9042
108 7MX 0.9042
109 JY2 0.9040
110 5E5 0.9039
111 MP5 0.9038
112 5OO 0.9038
113 4OG 0.9037
114 CIY 0.9034
115 S0G 0.9031
116 X0T 0.9031
117 3VX 0.9028
118 4FE 0.9027
119 MPP 0.9025
120 3D8 0.9024
121 5WU 0.9024
122 TB8 0.9021
123 6J9 0.9019
124 BK9 0.9017
125 LTN 0.9017
126 N7I 0.9015
127 MMS 0.9014
128 2KU 0.9013
129 CFA 0.9011
130 6DP 0.9011
131 CWD 0.9008
132 JXK 0.9007
133 8MP 0.9006
134 BB4 0.9006
135 M3Q 0.9005
136 15A 0.9001
137 MXD 0.9000
138 N2M 0.9000
139 JF1 0.8999
140 AX3 0.8998
141 52F 0.8995
142 92P 0.8994
143 RVE 0.8993
144 GI4 0.8992
145 2K8 0.8992
146 A4V 0.8991
147 B41 0.8989
148 3Y7 0.8988
149 DTR 0.8984
150 TU0 0.8982
151 9GP 0.8982
152 TMG 0.8981
153 SRO 0.8981
154 GB4 0.8979
155 A6P 0.8979
156 BWD 0.8975
157 55D 0.8974
158 CX4 0.8974
159 SYE 0.8973
160 M78 0.8972
161 67Y 0.8971
162 ZME 0.8970
163 JND 0.8970
164 MFZ 0.8970
165 7I2 0.8966
166 YOF 0.8965
167 ZEZ 0.8965
168 ITW 0.8963
169 D6G 0.8963
170 ZON 0.8962
171 QBM 0.8961
172 ABF 0.8961
173 DAH 0.8959
174 P7Y 0.8959
175 28S 0.8959
176 0FK 0.8955
177 KTW 0.8955
178 BPY 0.8954
179 R9Y 0.8953
180 5WS 0.8953
181 APS 0.8953
182 DTE 0.8952
183 YIH 0.8951
184 4KL 0.8949
185 ZRK 0.8948
186 H4B 0.8947
187 MQG 0.8946
188 CTE 0.8946
189 JYT 0.8943
190 EV2 0.8942
191 MIG 0.8942
192 8GK 0.8942
193 MD6 0.8941
194 ALE 0.8940
195 B4O 0.8939
196 THM 0.8939
197 EYJ 0.8938
198 LSQ 0.8938
199 HBO 0.8936
200 EY7 0.8934
201 5JT 0.8934
202 6GP 0.8933
203 T6Z 0.8933
204 4Z9 0.8932
205 RUG 0.8929
206 P0P 0.8926
207 8XL 0.8920
208 HJB 0.8919
209 5O5 0.8919
210 AY4 0.8918
211 327 0.8917
212 GZV 0.8917
213 EYV 0.8917
214 LDP 0.8916
215 DXK 0.8915
216 B61 0.8914
217 NTF 0.8914
218 3B4 0.8913
219 X48 0.8912
220 CG8 0.8912
221 6ZW 0.8911
222 977 0.8911
223 CMU 0.8910
224 NWD 0.8907
225 HC4 0.8906
226 EXR 0.8906
227 CHQ 0.8905
228 14W 0.8904
229 KMY 0.8900
230 OSB 0.8899
231 1Q4 0.8899
232 8Y7 0.8899
233 SJK 0.8899
234 ZRL 0.8898
235 C0W 0.8898
236 ONZ 0.8897
237 8NX 0.8896
238 2JK 0.8894
239 1SS 0.8893
240 89J 0.8890
241 F06 0.8890
242 C4E 0.8889
243 CCV 0.8889
244 LVD 0.8887
245 N91 0.8887
246 N1E 0.8887
247 IWD 0.8885
248 L07 0.8885
249 B5A 0.8885
250 NOK 0.8884
251 KP2 0.8884
252 BNX 0.8883
253 P80 0.8883
254 MBP 0.8883
255 2UD 0.8882
256 HBI 0.8882
257 S3C 0.8881
258 4BX 0.8879
259 GO2 0.8879
260 4AB 0.8873
261 GT1 0.8873
262 JP2 0.8873
263 KF5 0.8872
264 4MX 0.8869
265 0J5 0.8869
266 W8G 0.8868
267 JR2 0.8866
268 AJD 0.8866
269 YE7 0.8865
270 TOH 0.8865
271 GA2 0.8864
272 JTH 0.8860
273 BIO 0.8860
274 H2B 0.8858
275 363 0.8858
276 ESI 0.8858
277 AAN 0.8858
278 FNA 0.8857
279 LJ4 0.8857
280 SNY 0.8856
281 BGC 0.8854
282 K37 0.8854
283 2CZ 0.8854
284 H7Y 0.8853
285 KYN 0.8851
286 54X 0.8850
287 EXD 0.8850
288 LJ3 0.8850
289 MNP 0.8850
290 M4E 0.8849
291 22L 0.8848
292 2GQ 0.8846
293 LP8 0.8845
294 KLV 0.8844
295 GLC 0.8842
296 M5H 0.8841
297 7L4 0.8840
298 EMZ 0.8840
299 PE2 0.8838
300 61M 0.8837
301 QUB 0.8837
302 5WM 0.8837
303 ZYV 0.8836
304 5TY 0.8835
305 TRF 0.8834
306 ZYQ 0.8834
307 GDL 0.8833
308 LL1 0.8833
309 MUX 0.8833
310 M3E 0.8833
311 UFO 0.8833
312 MUK 0.8831
313 F40 0.8831
314 WA2 0.8831
315 CXH 0.8828
316 ZSP 0.8828
317 3R6 0.8826
318 A1Y 0.8825
319 657 0.8825
320 HWD 0.8824
321 0FR 0.8824
322 EV0 0.8822
323 VXX 0.8821
324 505 0.8820
325 F34 0.8820
326 XQI 0.8820
327 HSX 0.8819
328 535 0.8817
329 HA6 0.8816
330 TNX 0.8814
331 K68 0.8812
332 2O6 0.8811
333 S0W 0.8811
334 5B2 0.8810
335 3C4 0.8808
336 7AP 0.8807
337 KED 0.8807
338 FYR 0.8804
339 NDG 0.8803
340 6VD 0.8800
341 QZ8 0.8800
342 0W1 0.8800
343 790 0.8800
344 1BW 0.8799
345 E7S 0.8793
346 IL5 0.8791
347 NCV 0.8790
348 6J5 0.8789
349 GC2 0.8789
350 B2E 0.8789
351 KWB 0.8789
352 D8Q 0.8788
353 0XR 0.8788
354 CLU 0.8787
355 774 0.8787
356 42J 0.8787
357 6PB 0.8786
358 M02 0.8786
359 AVX 0.8785
360 BZE 0.8784
361 AEH 0.8784
362 EV3 0.8783
363 3IB 0.8782
364 96R 0.8782
365 5P3 0.8782
366 XCG 0.8778
367 C09 0.8777
368 4WF 0.8775
369 MIL 0.8775
370 TXW 0.8775
371 9ZE 0.8774
372 3AK 0.8773
373 AZY 0.8773
374 4ME 0.8773
375 B0K 0.8771
376 IPT 0.8769
377 H4E 0.8769
378 3JM 0.8769
379 VM1 0.8769
380 GXD 0.8768
381 BQ2 0.8767
382 M6Z 0.8767
383 9JT 0.8767
384 AZC 0.8765
385 4XF 0.8763
386 P4L 0.8762
387 EOL 0.8761
388 L3L 0.8760
389 TLG 0.8759
390 PBA 0.8758
391 KYA 0.8757
392 W81 0.8757
393 PH2 0.8757
394 M1Z 0.8756
395 8ZE 0.8755
396 HHR 0.8755
397 7PJ 0.8754
398 FT6 0.8754
399 MPU 0.8753
400 ZHA 0.8750
401 GNM 0.8749
402 Q5M 0.8749
403 92O 0.8748
404 GCS 0.8748
405 TL6 0.8746
406 2FX 0.8746
407 C2Y 0.8744
408 FUZ 0.8742
409 DI6 0.8742
410 HA5 0.8742
411 833 0.8740
412 NAL 0.8739
413 BHS 0.8739
414 IYR 0.8738
415 0OK 0.8737
416 0SY 0.8736
417 6L6 0.8736
418 1X8 0.8735
419 N2I 0.8735
420 22T 0.8734
421 BP7 0.8733
422 Z25 0.8733
423 3SU 0.8729
424 HHS 0.8729
425 5F5 0.8727
426 8WT 0.8727
427 0JD 0.8725
428 NYJ 0.8725
429 ZYW 0.8724
430 F6P 0.8724
431 6FZ 0.8720
432 263 0.8720
433 A7H 0.8719
434 HPP 0.8717
435 5NN 0.8717
436 F90 0.8717
437 AKD 0.8717
438 4B0 0.8717
439 ONR 0.8714
440 LNR 0.8713
441 EXG 0.8711
442 TLM 0.8711
443 428 0.8711
444 M4B 0.8711
445 P81 0.8710
446 ZYC 0.8709
447 DNF 0.8709
448 RKV 0.8708
449 S7G 0.8708
450 ZEC 0.8707
451 EUH 0.8707
452 STZ 0.8707
453 YX1 0.8707
454 3WJ 0.8705
455 A5P 0.8704
456 12R 0.8702
457 RP5 0.8701
458 CKU 0.8700
459 QME 0.8700
460 ASE 0.8700
461 LGC 0.8699
462 4Z1 0.8699
463 78U 0.8698
464 TYR 0.8698
465 BGN 0.8697
466 D87 0.8695
467 0F9 0.8694
468 QUS 0.8694
469 Y3L 0.8693
470 7GP 0.8691
471 K82 0.8691
472 IBC 0.8690
473 8HC 0.8689
474 AS3 0.8688
475 9H2 0.8686
476 TCA 0.8685
477 3L1 0.8684
478 9UL 0.8683
479 BIE 0.8683
480 7ZL 0.8681
481 5E4 0.8681
482 J6W 0.8680
483 9FE 0.8680
484 SKF 0.8678
485 3N1 0.8677
486 BC3 0.8675
487 M01 0.8673
488 CC5 0.8672
489 A2G 0.8671
490 GC3 0.8670
491 JYE 0.8670
492 G30 0.8667
493 15N 0.8666
494 4KR 0.8666
495 S8D 0.8665
496 NGA 0.8663
497 8G6 0.8663
498 GJP 0.8663
499 ZIQ 0.8663
500 DJN 0.8661
501 OW7 0.8661
502 LTM 0.8660
503 0J4 0.8660
504 ENO 0.8658
505 LYL 0.8655
506 6ZX 0.8653
507 512 0.8653
508 LZB 0.8651
509 7ME 0.8648
510 3GX 0.8648
511 NEO 0.8648
512 MUR 0.8647
513 MW5 0.8646
514 AVA 0.8644
515 3DT 0.8644
516 EVF 0.8642
517 36M 0.8640
518 HWH 0.8639
519 57D 0.8638
520 8NB 0.8635
521 SSM 0.8634
522 GCB 0.8634
523 N3W 0.8633
524 78P 0.8632
525 X0W 0.8631
526 DEE 0.8629
527 AHC 0.8627
528 TA6 0.8627
529 ETV 0.8625
530 6DQ 0.8622
531 CUH 0.8622
532 9KZ 0.8621
533 SQ7 0.8621
534 B21 0.8618
535 RD4 0.8615
536 0DN 0.8614
537 S0D 0.8614
538 HJH 0.8613
539 GNR 0.8612
540 4Z3 0.8611
541 1SV 0.8611
542 GAL 0.8611
543 BGU 0.8609
544 MQB 0.8607
545 P9I 0.8603
546 8RK 0.8603
547 3IP 0.8600
548 9R5 0.8598
549 1V3 0.8597
550 L46 0.8596
551 NHT 0.8596
552 PW1 0.8595
553 4AV 0.8595
554 LRW 0.8595
555 ALX 0.8594
556 X0U 0.8592
557 PTS 0.8592
558 LQG 0.8591
559 CBE 0.8590
560 QIV 0.8589
561 DEW 0.8589
562 Y0V 0.8585
563 DBS 0.8584
564 1A7 0.8583
565 JO5 0.8583
566 HCI 0.8583
567 LOG 0.8582
568 JHY 0.8581
569 4I8 0.8578
570 BRH 0.8577
571 PFF 0.8575
572 2LX 0.8574
573 IQ5 0.8573
574 TZP 0.8569
575 B2J 0.8568
576 CDY 0.8565
577 H7S 0.8565
578 P2L 0.8562
579 531 0.8562
580 CUT 0.8555
581 XIZ 0.8554
582 GL6 0.8554
583 H5B 0.8551
584 42R 0.8549
585 54E 0.8546
586 GZ2 0.8545
587 R2P 0.8542
588 IMK 0.8541
589 DG2 0.8540
590 MOK 0.8539
591 YIP 0.8535
592 5F1 0.8532
593 3D1 0.8532
594 28A 0.8531
595 GHM 0.8531
596 AM1 0.8528
597 5F8 0.8528
598 ESP 0.8524
599 SHG 0.8523
600 5O6 0.8522
601 PYU 0.8522
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LP1; Ligand: 71H; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5lp1.bio1) has 30 residues
No: Leader PDB Ligand Sequence Similarity
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