Receptor
PDB id Resolution Class Description Source Keywords
2Q95 1.7 Å EC: 3.4.11.18 E. COLI METHIONINE AMINOPEPTIDASE MN-FORM WITH INHIBITOR A05 ESCHERICHIA COLI AMINOPEPTIDASE HYDROLASE DINUCLEAR MN(II)-FORM ENZYME- INHIBITOR COMPLEX METALLOENZYME
Ref.: STRUCTURAL ANALYSIS OF INHIBITION OF E. COLI METHIONINE AMINOPEPTIDASE: IMPLICATION OF LOOP FLEXIBILITY IN SELECTIVE INHIBITION OF BACTERIAL ENZYMES. BMC STRUCT.BIOL. V. 7 84 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
A05 A:400;
 Valid;
 none;
 ic50 = 1.6 uM
267.622 C11 H6 Cl N O5 c1cc(...
MN A:301;
A:302;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
54.938 Mn [Mn+2...
NA A:500;
 Part of Protein;
 none;
 submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YVM 1.6 Å EC: 3.4.11.18 E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH THIABENDAZOLE ESCHERICHIA COLI HYDROLASE(ALPHA-AMINOACYLPEPTIDE) METAL COMPLEX THIABENDAZOLE METHIONINE AMINOPEPTIDASE INHIBITOR
Ref.: METAL IONS AS COFACTORS FOR THE BINDING OF INHIBITORS TO METHIONINE AMINOPEPTIDASE: A CRITICAL VIEW OF THE RELEVANCE OF IN VITRO METALLOENZYME ASSAYS. ANGEW.CHEM.INT.ED.ENGL. V. 44 3620 2005
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
70% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
50% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2NQ6 ic50 = 1.5 uM HM4 C14 H16 N4 O3 S CC(C)(C)OC....
2 4U69 Ki = 54.8 uM Q07 C6 H16 N O3 P CCC[C@H](C....
3 2G6P ic50 = 0.6 uM HM2 C18 H17 Cl N4 Cc1c(c(nc(....
4 4U73 Ki = 6.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
5 4IKT ic50 = 0.67 uM TFV C18 H16 Cl F3 N6 Cc1c(c(nc(....
6 4U6Z Ki = 3.9 uM Q07 C6 H16 N O3 P CCC[C@H](C....
7 4U70 Ki = 9.5 uM Q04 C8 H18 N O3 P C1CCC(CC1)....
8 4FLI ic50 = 3.59 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
9 4U6C Ki = 9.9 uM Q06 C8 H18 N O3 P C1CCC(C1)C....
10 4IKR ic50 = 0.59 uM PVP C16 H20 Cl N5 O Cc1c(c(nc(....
11 4FLK ic50 = 5.58 uM Y10 C21 H31 N O5 CC(C)(C)/C....
12 4IKU ic50 = 1.79 uM SHX C19 H18 Cl N5 O Cc1c(c(nc(....
13 2NQ7 ic50 = 2.9 uM HM5 C14 H16 N4 O2 S CC(C)(C)C(....
14 4FLL ic50 = 5.14 uM YZ6 C25 H35 N O6 CC(C)(C)/C....
15 4U71 Ki = 6 uM Q03 C7 H16 N O3 P C1CCC(CC1)....
16 4HXX - 1AY C28 H29 Cl2 N5 Cc1c(c(nc(....
17 4IKS ic50 = 7.23 uM TFD C18 H16 Cl F3 N6 Cc1c(c(nc(....
18 4U6E Ki = 111.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
19 4U1B Ki = 4.9 uM Q08 C8 H20 N O3 P CCCC(CCC)[....
20 4FLJ ic50 = 7.45 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
21 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
22 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
23 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
24 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
25 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
26 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
27 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
28 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
29 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
30 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
31 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
32 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
33 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
34 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
35 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
36 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
37 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
38 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
39 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
40 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
41 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
42 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
43 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
44 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
45 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
46 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
47 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
48 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
49 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
50 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
51 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
52 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
53 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
54 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
55 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
56 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
57 4IU6 - FZ1 C24 H23 N5 O COc1ccc(cc....
58 1QXZ ic50 = 19 uM M3C C8 H14 N2 O2 S2 CSCC[C@@H]....
59 1QXY ic50 = 16 uM M2C C10 H16 N2 O2 S CSCC[C@@H]....
60 1QXW ic50 = 7 uM M1C C10 H22 N2 O2 CCCC[C@@H]....
61 3IU9 ic50 = 0.24 uM T07 C9 H8 Cl2 N4 S c1cc(c(cc1....
62 3IU7 ic50 = 16 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
63 3PKE - Y10 C21 H31 N O5 CC(C)(C)/C....
64 3PKB ic50 = 0.62 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
65 3PKA ic50 = 0.54 uM Y02 C23 H37 N O6 Cc1cc(c(c(....
66 3PKC ic50 = 0.96 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
67 3IU8 ic50 = 0.58 uM T03 C9 H8 F N3 S c1cc(ccc1C....
68 3PKD ic50 = 0.76 uM Y10 C21 H31 N O5 CC(C)(C)/C....
69 1YJ3 - MET C5 H11 N O2 S CSCC[C@@H]....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: A05; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 A05 1 1
2 B23 0.466667 0.893617
Similar Ligands (3D)
Ligand no: 1; Ligand: A05; Similar ligands found: 409
No: Ligand Similarity coefficient
1 TVZ 0.9561
2 109 0.9502
3 U4J 0.9463
4 BMC 0.9433
5 MBT 0.9385
6 JL7 0.9370
7 Q92 0.9368
8 1DR 0.9347
9 Q2S 0.9332
10 Q8G 0.9326
11 BMZ 0.9326
12 CR4 0.9320
13 TVC 0.9319
14 1SF 0.9314
15 S1C 0.9259
16 J1K 0.9258
17 NZ4 0.9254
18 NIF 0.9238
19 AO 0.9233
20 GF7 0.9226
21 OJ7 0.9215
22 WG8 0.9208
23 BBP 0.9206
24 6QT 0.9197
25 120 0.9190
26 5OR 0.9189
27 97K 0.9185
28 272 0.9180
29 801 0.9176
30 ESJ 0.9171
31 124 0.9167
32 72G 0.9166
33 4UM 0.9165
34 VBC 0.9159
35 Q0K 0.9154
36 1XS 0.9149
37 1V3 0.9144
38 122 0.9136
39 HRD 0.9126
40 BX4 0.9126
41 RGK 0.9124
42 LIG 0.9119
43 S1D 0.9112
44 Z3R 0.9111
45 IDZ 0.9110
46 121 0.9107
47 ZTW 0.9104
48 OLU 0.9103
49 0K7 0.9101
50 AD6 0.9098
51 HMZ 0.9096
52 JSX 0.9093
53 802 0.9090
54 A9B 0.9089
55 1V0 0.9088
56 1UR 0.9088
57 KWV 0.9083
58 0DJ 0.9081
59 EES 0.9067
60 6JM 0.9064
61 4ZF 0.9063
62 8V8 0.9063
63 AJG 0.9060
64 47X 0.9059
65 H4B 0.9055
66 27F 0.9052
67 JFS 0.9051
68 SJR 0.9050
69 BXS 0.9049
70 LC1 0.9049
71 5VU 0.9046
72 08C 0.9045
73 WDW 0.9042
74 WA1 0.9040
75 NKI 0.9039
76 EEY 0.9034
77 KU1 0.9032
78 XAV 0.9020
79 1V4 0.9020
80 1UT 0.9020
81 3Q0 0.9020
82 RPN 0.9020
83 GEN 0.9014
84 SNJ 0.9009
85 4CN 0.9008
86 MR4 0.9005
87 AQN 0.9005
88 856 0.9005
89 0UL 0.9004
90 DX7 0.9002
91 68C 0.9002
92 GJG 0.9002
93 1HP 0.9000
94 UN9 0.8990
95 6H2 0.8989
96 TID 0.8987
97 517 0.8984
98 LUM 0.8982
99 5M2 0.8981
100 1UZ 0.8980
101 CUE 0.8980
102 FHV 0.8979
103 AJ1 0.8978
104 72H 0.8977
105 A8D 0.8975
106 1FL 0.8973
107 20D 0.8971
108 MKN 0.8969
109 O53 0.8966
110 LU2 0.8963
111 DFL 0.8963
112 LR8 0.8961
113 F36 0.8960
114 K8W 0.8960
115 7G2 0.8959
116 G2V 0.8959
117 AV7 0.8958
118 C0V 0.8956
119 338 0.8956
120 397 0.8956
121 L43 0.8955
122 PRL 0.8955
123 245 0.8953
124 EQU 0.8952
125 205 0.8952
126 4NR 0.8951
127 2WU 0.8951
128 6JO 0.8949
129 2PK 0.8948
130 123 0.8948
131 29F 0.8946
132 40N 0.8945
133 IXM 0.8942
134 2P3 0.8941
135 1V1 0.8938
136 A63 0.8938
137 3F4 0.8936
138 3SU 0.8935
139 F40 0.8935
140 1V8 0.8934
141 BRY 0.8933
142 T21 0.8932
143 2UV 0.8929
144 DDC 0.8927
145 4HG 0.8927
146 4AU 0.8926
147 PIQ 0.8926
148 SZ5 0.8922
149 J84 0.8921
150 20N 0.8919
151 K7H 0.8919
152 WLH 0.8919
153 27M 0.8918
154 DFV 0.8915
155 WF4 0.8911
156 D26 0.8909
157 7ZO 0.8908
158 F08 0.8908
159 FHI 0.8908
160 RF2 0.8904
161 SU9 0.8904
162 6FX 0.8904
163 23M 0.8904
164 25F 0.8904
165 FBC 0.8903
166 2QV 0.8903
167 907 0.8902
168 7FZ 0.8899
169 NVS 0.8896
170 0MB 0.8893
171 39Z 0.8893
172 H2B 0.8892
173 MR5 0.8891
174 833 0.8890
175 HH6 0.8889
176 5TU 0.8888
177 S0D 0.8884
178 D25 0.8883
179 A73 0.8880
180 LZ4 0.8879
181 OUG 0.8878
182 A64 0.8877
183 47V 0.8875
184 L03 0.8874
185 MT6 0.8868
186 3WL 0.8865
187 EST 0.8863
188 BSU 0.8862
189 AP6 0.8861
190 AX1 0.8861
191 K3T 0.8860
192 06R 0.8858
193 A45 0.8854
194 NPX 0.8852
195 90G 0.8850
196 GN5 0.8850
197 D64 0.8849
198 CDJ 0.8847
199 797 0.8846
200 7DE 0.8844
201 1Q1 0.8844
202 4EU 0.8841
203 0DF 0.8839
204 334 0.8839
205 FNT 0.8836
206 5S9 0.8834
207 II4 0.8831
208 E92 0.8829
209 EI1 0.8829
210 B1J 0.8828
211 2QU 0.8827
212 YE6 0.8827
213 H2W 0.8826
214 D1Y 0.8826
215 1FE 0.8825
216 JMM 0.8825
217 6DH 0.8825
218 K4T 0.8825
219 XEV 0.8825
220 L1T 0.8825
221 52F 0.8822
222 PQM 0.8822
223 RSV 0.8821
224 W8L 0.8820
225 DX2 0.8819
226 JCQ 0.8819
227 28A 0.8818
228 5H6 0.8817
229 GA6 0.8815
230 E9L 0.8815
231 0NJ 0.8814
232 OT4 0.8814
233 CX4 0.8812
234 EZL 0.8812
235 6BK 0.8811
236 39R 0.8811
237 PIC 0.8811
238 FCD 0.8810
239 CU8 0.8806
240 N5B 0.8805
241 5O6 0.8805
242 NPS 0.8802
243 JVD 0.8802
244 ARJ 0.8802
245 A9E 0.8799
246 CX5 0.8799
247 7EH 0.8798
248 6DQ 0.8797
249 U55 0.8796
250 91F 0.8792
251 31F 0.8790
252 7FU 0.8790
253 TCR 0.8790
254 RYJ 0.8789
255 5ZM 0.8788
256 1R5 0.8787
257 GB4 0.8787
258 28B 0.8785
259 S8P 0.8785
260 S98 0.8785
261 5TT 0.8785
262 15Q 0.8782
263 HWB 0.8780
264 0OK 0.8779
265 62D 0.8775
266 LI7 0.8774
267 P7V 0.8771
268 4AB 0.8770
269 QUE 0.8770
270 IPJ 0.8770
271 ECS 0.8769
272 8M5 0.8769
273 7EL 0.8766
274 NEO 0.8765
275 6SD 0.8763
276 5TO 0.8763
277 NRA 0.8762
278 FCW 0.8761
279 A5H 0.8760
280 DBE 0.8760
281 ZEA 0.8759
282 Q7U 0.8758
283 9ME 0.8755
284 E98 0.8753
285 P4L 0.8753
286 CWE 0.8749
287 W2E 0.8749
288 BBY 0.8747
289 A6W 0.8747
290 HBI 0.8746
291 BVS 0.8746
292 STR 0.8745
293 1EL 0.8745
294 CX6 0.8744
295 RKY 0.8743
296 22T 0.8741
297 QS4 0.8740
298 SJK 0.8739
299 3K1 0.8739
300 B21 0.8737
301 0SX 0.8737
302 2ZI 0.8735
303 U14 0.8734
304 1AJ 0.8733
305 YZ9 0.8733
306 IQW 0.8732
307 XYP XYP 0.8732
308 MQS 0.8731
309 L4K 0.8731
310 DUR 0.8729
311 KHP 0.8729
312 AGI 0.8728
313 NAR 0.8726
314 MR6 0.8726
315 9JT 0.8725
316 108 0.8723
317 5WW 0.8722
318 AVX 0.8719
319 3NM 0.8719
320 FYR 0.8716
321 VT3 0.8714
322 S0J 0.8712
323 ET0 0.8711
324 MQR 0.8711
325 M3W 0.8709
326 HPX 0.8709
327 1EB 0.8708
328 3MI 0.8706
329 EY2 0.8706
330 BIO 0.8705
331 NEU 0.8701
332 5KN 0.8697
333 789 0.8696
334 7KE 0.8696
335 DX8 0.8695
336 H75 0.8691
337 ESM 0.8690
338 AZN 0.8690
339 AUG 0.8686
340 MI2 0.8685
341 IY5 0.8683
342 103 0.8683
343 FSE 0.8682
344 01I 0.8682
345 JBB 0.8679
346 KP2 0.8679
347 2JX 0.8678
348 GUS 0.8676
349 DH2 0.8675
350 A26 0.8672
351 4FF 0.8671
352 5C1 0.8668
353 7G0 0.8667
354 C4E 0.8666
355 6C5 0.8664
356 4G2 0.8661
357 L2K 0.8660
358 VGV 0.8657
359 YE7 0.8656
360 KLE 0.8654
361 2JP 0.8650
362 X2L 0.8648
363 LJ5 0.8647
364 XYS XYS 0.8646
365 5R9 0.8644
366 C4F 0.8643
367 F18 0.8641
368 DN8 0.8640
369 M29 0.8637
370 PMM 0.8634
371 CC6 0.8633
372 KMP 0.8631
373 FC2 0.8630
374 NK5 0.8630
375 E3U 0.8627
376 9MK 0.8626
377 RYY 0.8625
378 QNM 0.8624
379 U13 0.8623
380 72D 0.8623
381 TEF 0.8622
382 4AJ 0.8618
383 57D 0.8618
384 FX5 0.8618
385 LZ7 0.8617
386 6F3 0.8605
387 3VQ 0.8605
388 EAT 0.8602
389 U12 0.8600
390 OSY 0.8599
391 VFJ 0.8598
392 IXG 0.8596
393 2GQ 0.8592
394 N9M 0.8592
395 8CC 0.8591
396 URI 0.8588
397 Q4G 0.8587
398 RDV 0.8586
399 KWD 0.8578
400 BC5 0.8577
401 9KZ 0.8571
402 68B 0.8566
403 0XR 0.8564
404 AUE 0.8557
405 7FC 0.8553
406 5BX 0.8551
407 4P9 0.8540
408 3WO 0.8525
409 3WN 0.8525
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YVM; Ligand: TMG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1yvm.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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