Receptor
PDB id Resolution Class Description Source Keywords
2GG3 1.45 Å EC: 3.4.11.18 NOVEL BACTERIAL METHIONINE AMINOPEPTIDASE INHIBITORS ESCHERICHIA COLI K12 METHIONINE AMINO PEPTIDASE PITA-BREAD FOLD MAP INHIBITOR ANTIBACTERIAL HYDROLASE
Ref.: SERENDIPITOUS DISCOVERY OF NOVEL BACTERIAL METHIONINE AMINOPEPTIDASE INHIBITORS. PROTEINS V. 66 538 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CO A:301;
A:302;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
58.933 Co [Co+2...
NA A:503;
 Part of Protein;
 none;
 submit data
22.99 Na [Na+]
U13 A:501;
 Valid;
 none;
 ic50 = 0.58 uM
218.19 C9 H7 F N6 [H]/N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YVM 1.6 Å EC: 3.4.11.18 E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH THIABENDAZOLE ESCHERICHIA COLI HYDROLASE(ALPHA-AMINOACYLPEPTIDE) METAL COMPLEX THIABENDAZOLE METHIONINE AMINOPEPTIDASE INHIBITOR
Ref.: METAL IONS AS COFACTORS FOR THE BINDING OF INHIBITORS TO METHIONINE AMINOPEPTIDASE: A CRITICAL VIEW OF THE RELEVANCE OF IN VITRO METALLOENZYME ASSAYS. ANGEW.CHEM.INT.ED.ENGL. V. 44 3620 2005
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
70% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
50% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2NQ6 ic50 = 1.5 uM HM4 C14 H16 N4 O3 S CC(C)(C)OC....
2 4U69 Ki = 54.8 uM Q07 C6 H16 N O3 P CCC[C@H](C....
3 2G6P ic50 = 0.6 uM HM2 C18 H17 Cl N4 Cc1c(c(nc(....
4 4U73 Ki = 6.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
5 4IKT ic50 = 0.67 uM TFV C18 H16 Cl F3 N6 Cc1c(c(nc(....
6 4U6Z Ki = 3.9 uM Q07 C6 H16 N O3 P CCC[C@H](C....
7 4U70 Ki = 9.5 uM Q04 C8 H18 N O3 P C1CCC(CC1)....
8 4FLI ic50 = 3.59 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
9 4U6C Ki = 9.9 uM Q06 C8 H18 N O3 P C1CCC(C1)C....
10 4IKR ic50 = 0.59 uM PVP C16 H20 Cl N5 O Cc1c(c(nc(....
11 4FLK ic50 = 5.58 uM Y10 C21 H31 N O5 CC(C)(C)/C....
12 4IKU ic50 = 1.79 uM SHX C19 H18 Cl N5 O Cc1c(c(nc(....
13 2NQ7 ic50 = 2.9 uM HM5 C14 H16 N4 O2 S CC(C)(C)C(....
14 4FLL ic50 = 5.14 uM YZ6 C25 H35 N O6 CC(C)(C)/C....
15 4U71 Ki = 6 uM Q03 C7 H16 N O3 P C1CCC(CC1)....
16 4HXX - 1AY C28 H29 Cl2 N5 Cc1c(c(nc(....
17 4IKS ic50 = 7.23 uM TFD C18 H16 Cl F3 N6 Cc1c(c(nc(....
18 4U6E Ki = 111.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
19 4U1B Ki = 4.9 uM Q08 C8 H20 N O3 P CCCC(CCC)[....
20 4FLJ ic50 = 7.45 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
21 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
22 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
23 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
24 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
25 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
26 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
27 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
28 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
29 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
30 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
31 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
32 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
33 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
34 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
35 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
36 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
37 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
38 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
39 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
40 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
41 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
42 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
43 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
44 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
45 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
46 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
47 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
48 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
49 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
50 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
51 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
52 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
53 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
54 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
55 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
56 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
57 4IU6 - FZ1 C24 H23 N5 O COc1ccc(cc....
58 1QXZ ic50 = 19 uM M3C C8 H14 N2 O2 S2 CSCC[C@@H]....
59 1QXY ic50 = 16 uM M2C C10 H16 N2 O2 S CSCC[C@@H]....
60 1QXW ic50 = 7 uM M1C C10 H22 N2 O2 CCCC[C@@H]....
61 3IU9 ic50 = 0.24 uM T07 C9 H8 Cl2 N4 S c1cc(c(cc1....
62 3IU7 ic50 = 16 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
63 3PKE - Y10 C21 H31 N O5 CC(C)(C)/C....
64 3PKB ic50 = 0.62 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
65 3PKA ic50 = 0.54 uM Y02 C23 H37 N O6 Cc1cc(c(c(....
66 3PKC ic50 = 0.96 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
67 3IU8 ic50 = 0.58 uM T03 C9 H8 F N3 S c1cc(ccc1C....
68 3PKD ic50 = 0.76 uM Y10 C21 H31 N O5 CC(C)(C)/C....
69 1YJ3 - MET C5 H11 N O2 S CSCC[C@@H]....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: U13; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 U13 1 1
2 U12 0.465517 0.928571
3 U14 0.440678 0.782609
4 U19 0.40678 0.886364
Similar Ligands (3D)
Ligand no: 1; Ligand: U13; Similar ligands found: 532
No: Ligand Similarity coefficient
1 F18 1.0000
2 A51 0.9684
3 ERZ 0.9582
4 MR4 0.9560
5 ZRK 0.9556
6 S0D 0.9505
7 AOY 0.9504
8 RGK 0.9489
9 NKI 0.9466
10 ZRL 0.9465
11 9JT 0.9427
12 0SY 0.9423
13 IDZ 0.9397
14 0NJ 0.9379
15 MR5 0.9374
16 MR6 0.9374
17 38E 0.9366
18 L2K 0.9358
19 1V1 0.9351
20 WLH 0.9350
21 A9B 0.9343
22 A63 0.9341
23 A73 0.9340
24 20D 0.9338
25 DFL 0.9333
26 1HP 0.9332
27 47V 0.9328
28 TPM 0.9327
29 08C 0.9326
30 6H2 0.9320
31 G2V 0.9299
32 JF8 0.9297
33 6T5 0.9289
34 CDJ 0.9280
35 5B2 0.9280
36 3D8 0.9273
37 E3X 0.9273
38 FHV 0.9269
39 4FF 0.9269
40 PIQ 0.9268
41 MJW 0.9267
42 W8L 0.9266
43 H2W 0.9264
44 WA1 0.9263
45 EMU 0.9258
46 397 0.9258
47 1XS 0.9258
48 LZ5 0.9256
49 A5H 0.9256
50 68B 0.9252
51 YE6 0.9251
52 0XR 0.9246
53 245 0.9244
54 KLS 0.9244
55 3IP 0.9241
56 25F 0.9241
57 3F4 0.9239
58 OLU 0.9239
59 0ON 0.9237
60 SZ5 0.9235
61 0K7 0.9234
62 F40 0.9227
63 S1D 0.9224
64 VBC 0.9223
65 JSX 0.9221
66 UAY 0.9220
67 X48 0.9217
68 E9L 0.9216
69 5TU 0.9215
70 C4E 0.9215
71 4HB 0.9215
72 5E5 0.9211
73 5WW 0.9211
74 1A5 0.9206
75 ZTW 0.9204
76 7FZ 0.9203
77 NE2 0.9203
78 1UZ 0.9199
79 BP7 0.9196
80 M3W 0.9192
81 ZEA 0.9191
82 0UL 0.9190
83 27F 0.9188
84 DXK 0.9187
85 4GU 0.9185
86 28A 0.9182
87 11X 0.9176
88 2QU 0.9176
89 FZM 0.9172
90 PCQ 0.9169
91 STL 0.9165
92 5VU 0.9163
93 BMZ 0.9162
94 WCU 0.9162
95 VT3 0.9161
96 BVS 0.9161
97 CR4 0.9160
98 3VQ 0.9157
99 JFS 0.9154
100 XCG 0.9153
101 NU3 0.9149
102 4Z1 0.9145
103 801 0.9142
104 6BK 0.9141
105 4AU 0.9141
106 97K 0.9141
107 2D2 0.9140
108 U4J 0.9138
109 QC1 0.9138
110 TRP 0.9131
111 MHB 0.9130
112 91F 0.9129
113 0DF 0.9128
114 ITE 0.9127
115 120 0.9127
116 4ZF 0.9126
117 LOT 0.9122
118 NW1 0.9118
119 2QV 0.9111
120 XDL XYP 0.9111
121 TMG 0.9109
122 6J5 0.9103
123 XIF XYP 0.9101
124 124 0.9099
125 ODK 0.9098
126 FCD 0.9098
127 1V8 0.9097
128 XIL 0.9097
129 HRM 0.9093
130 D64 0.9092
131 9CE 0.9090
132 XYP XYP 0.9089
133 2PK 0.9085
134 SJR 0.9085
135 EQA 0.9080
136 5S9 0.9079
137 2PV 0.9078
138 AVX 0.9076
139 GB5 0.9076
140 A5Q 0.9071
141 78Y 0.9069
142 6P3 0.9066
143 XYP XDN 0.9066
144 FBC 0.9059
145 QME 0.9057
146 18E 0.9057
147 XDN XYP 0.9057
148 833 0.9054
149 2JX 0.9053
150 1FL 0.9050
151 697 0.9049
152 G14 0.9048
153 XYP XIF 0.9045
154 S98 0.9044
155 FY8 0.9043
156 6MW 0.9043
157 LJ5 0.9039
158 OJD 0.9039
159 MRE 0.9038
160 2WU 0.9037
161 CMG 0.9033
162 PRL 0.9031
163 2UV 0.9030
164 XYS XYS 0.9030
165 IIH 0.9028
166 LR2 0.9028
167 TCC 0.9026
168 ZZA 0.9024
169 H75 0.9023
170 6C8 0.9017
171 CBE 0.9011
172 272 0.9010
173 XI7 0.9009
174 LJ2 0.9008
175 7G2 0.9006
176 WG8 0.9003
177 H35 0.9003
178 0OP 0.8999
179 BVB 0.8998
180 AGI 0.8998
181 5NN 0.8997
182 LJ1 0.8995
183 P4T 0.8994
184 3N0 0.8993
185 JAH 0.8991
186 4RG 0.8990
187 F36 0.8989
188 5OR 0.8986
189 3SU 0.8986
190 6FG 0.8985
191 5ZM 0.8984
192 EES 0.8983
193 A6W 0.8982
194 5F8 0.8981
195 AUY 0.8975
196 041 0.8975
197 5TO 0.8974
198 NIY 0.8974
199 1V0 0.8973
200 A64 0.8971
201 MUK 0.8968
202 26C 0.8967
203 GVI 0.8966
204 0OK 0.8966
205 DAH 0.8966
206 7L4 0.8964
207 FF2 0.8963
208 JCZ 0.8960
209 3GX 0.8958
210 EAT 0.8958
211 SX2 0.8958
212 2P3 0.8958
213 LJ3 0.8957
214 5TT 0.8957
215 GVY 0.8955
216 LUM 0.8953
217 FC2 0.8952
218 7EH 0.8951
219 5WK 0.8951
220 363 0.8949
221 SQM 0.8948
222 122 0.8947
223 1UT 0.8946
224 VC3 0.8945
225 4CN 0.8945
226 1UR 0.8945
227 JF5 0.8945
228 FYR 0.8940
229 S60 0.8939
230 LR8 0.8938
231 P2L 0.8938
232 6SD 0.8936
233 XYP XYS 0.8935
234 4FP 0.8935
235 PQM 0.8935
236 KWB 0.8934
237 AP6 0.8934
238 TVZ 0.8934
239 5H6 0.8933
240 YE7 0.8930
241 B21 0.8929
242 3WJ 0.8929
243 RKV 0.8926
244 SGW 0.8926
245 FER 0.8925
246 0X2 0.8923
247 B1J 0.8922
248 QIV 0.8920
249 Q2S 0.8919
250 IPJ 0.8918
251 SWX 0.8918
252 6FB 0.8916
253 GJG 0.8913
254 FQX 0.8913
255 Q0K 0.8913
256 8G6 0.8912
257 H4B 0.8910
258 121 0.8909
259 BSU 0.8909
260 2J1 0.8907
261 IW2 0.8903
262 IW1 0.8903
263 JMG 0.8903
264 K0G 0.8902
265 338 0.8901
266 GAT 0.8900
267 HH6 0.8896
268 JRO 0.8896
269 EQW 0.8895
270 DHC 0.8889
271 7G0 0.8889
272 7ZO 0.8888
273 ZSP 0.8887
274 ZIP 0.8886
275 83D 0.8885
276 5FL 0.8884
277 AVA 0.8881
278 2FX 0.8879
279 ZHA 0.8876
280 4K2 0.8874
281 8UY 0.8873
282 MXD 0.8873
283 1SF 0.8872
284 3WK 0.8871
285 VUP 0.8871
286 RSV 0.8870
287 1G9 0.8870
288 HC4 0.8870
289 S0A 0.8869
290 BJ4 0.8869
291 GOE 0.8864
292 8M5 0.8863
293 1V4 0.8862
294 3VS 0.8857
295 HRD 0.8857
296 BMC 0.8856
297 BX4 0.8856
298 IEE 0.8855
299 NAL 0.8852
300 6C4 0.8852
301 DNQ 0.8852
302 TCR 0.8850
303 IW6 0.8849
304 1V3 0.8849
305 IDD 0.8848
306 6DQ 0.8844
307 613 0.8844
308 1Q1 0.8844
309 1DR 0.8843
310 4F8 0.8843
311 FCW 0.8841
312 KLE 0.8841
313 WV7 0.8841
314 1ZC 0.8840
315 WA2 0.8835
316 X2M 0.8834
317 6C5 0.8833
318 GB4 0.8832
319 KWV 0.8832
320 EDG AHR 0.8831
321 2M7 0.8831
322 NAR 0.8831
323 4G2 0.8830
324 UN4 0.8830
325 LI7 0.8826
326 BGU 0.8826
327 SNV 0.8825
328 NE1 0.8824
329 4BX 0.8824
330 XYS XYP 0.8823
331 1Q4 0.8823
332 PUE 0.8823
333 FMQ 0.8823
334 P81 0.8821
335 P4L 0.8820
336 D9Z 0.8819
337 KHP 0.8818
338 28B 0.8817
339 O53 0.8814
340 O9T 0.8814
341 O9Z 0.8812
342 JGB 0.8812
343 2LT 0.8810
344 68C 0.8809
345 HL6 0.8809
346 LU2 0.8807
347 BIK 0.8806
348 4FC 0.8806
349 MBP 0.8804
350 TID 0.8804
351 5R8 0.8802
352 EDZ 0.8801
353 4L2 0.8800
354 37E 0.8796
355 BBY 0.8796
356 Q4G 0.8795
357 Z70 0.8795
358 IQQ 0.8792
359 1KN 0.8791
360 8CC 0.8788
361 DFV 0.8788
362 L5D 0.8787
363 72D 0.8785
364 907 0.8783
365 0LO 0.8782
366 2L1 0.8782
367 6QF 0.8781
368 1FE 0.8781
369 4FE 0.8776
370 B4L 0.8775
371 Q92 0.8774
372 DDC 0.8773
373 5P3 0.8770
374 GJB 0.8770
375 GJK 0.8770
376 LO1 0.8768
377 ANC 0.8767
378 BZE 0.8767
379 LVP 0.8766
380 M4N 0.8764
381 8D6 0.8764
382 5ER 0.8763
383 ENO 0.8762
384 Y3L 0.8761
385 CJZ 0.8761
386 334 0.8760
387 GEN 0.8759
388 6TJ 0.8759
389 72G 0.8756
390 GO2 0.8756
391 IOP 0.8755
392 ARJ 0.8755
393 SB7 0.8753
394 II4 0.8753
395 CNI 0.8752
396 D1Y 0.8752
397 244 0.8751
398 L03 0.8749
399 JNW 0.8748
400 5CQ 0.8746
401 IMK 0.8742
402 3Q0 0.8738
403 DBS 0.8737
404 UL1 0.8734
405 TH1 0.8734
406 2GQ 0.8733
407 LMZ 0.8731
408 IW3 0.8728
409 TYR 0.8724
410 CX6 0.8723
411 NOC 0.8721
412 CZ0 0.8720
413 802 0.8718
414 D25 0.8716
415 AJG 0.8716
416 IW5 0.8715
417 5AD 0.8714
418 BIO 0.8714
419 8HH 0.8713
420 0FR 0.8710
421 5CK 0.8708
422 RE2 0.8707
423 NX1 0.8707
424 135 0.8706
425 FHI 0.8704
426 1EB 0.8702
427 NXY 0.8701
428 7O4 0.8701
429 L3L 0.8699
430 5WT 0.8697
431 AWE 0.8697
432 PQS 0.8695
433 94X 0.8694
434 EQU 0.8693
435 AUV 0.8691
436 TVC 0.8691
437 X0U 0.8691
438 JFZ 0.8690
439 3D3 0.8689
440 5TY 0.8689
441 P93 0.8688
442 ESE 0.8688
443 NBZ GLA 0.8686
444 4P9 0.8684
445 1Q2 0.8684
446 NXB 0.8683
447 S7D 0.8683
448 K80 0.8682
449 6WU 0.8681
450 5TZ 0.8677
451 3VX 0.8674
452 57D 0.8672
453 27M 0.8670
454 ARG 0.8667
455 N9M 0.8664
456 2QC 0.8663
457 ESJ 0.8663
458 GO8 0.8662
459 92G 0.8662
460 6C9 0.8660
461 3WL 0.8660
462 D26 0.8659
463 9BF 0.8657
464 8V8 0.8655
465 AHR AHR 0.8654
466 JA5 0.8652
467 29F 0.8652
468 3D1 0.8652
469 PIT 0.8650
470 KYN 0.8647
471 DMB 0.8645
472 GZ2 0.8645
473 KLV 0.8645
474 2ZI 0.8641
475 S8P 0.8638
476 72E 0.8637
477 F02 0.8637
478 C9M 0.8636
479 EST 0.8636
480 IY5 0.8635
481 M3E 0.8635
482 A26 0.8633
483 2PW 0.8633
484 4YE 0.8632
485 K7H 0.8629
486 3WN 0.8627
487 3WO 0.8627
488 6JP 0.8625
489 A05 0.8623
490 C53 0.8622
491 BU7 0.8621
492 6QT 0.8618
493 CWE 0.8616
494 2Q0 0.8616
495 XAV 0.8616
496 N91 0.8611
497 BRY 0.8611
498 4CF 0.8610
499 DBE 0.8609
500 TIA 0.8607
501 CHQ 0.8602
502 J45 0.8602
503 N9J 0.8601
504 SSY 0.8600
505 PZX 0.8599
506 1AJ 0.8599
507 0NX 0.8596
508 5CJ 0.8594
509 T21 0.8593
510 FLF 0.8591
511 JWS 0.8588
512 LFN 0.8583
513 5P7 0.8582
514 DX2 0.8581
515 NRA 0.8581
516 5DE 0.8579
517 T5J 0.8574
518 HXY 0.8573
519 THM 0.8570
520 4AF 0.8562
521 8BD 0.8556
522 HBI 0.8555
523 56N 0.8555
524 STV 0.8549
525 ZYQ 0.8543
526 06R 0.8539
527 DE7 0.8539
528 Z94 0.8535
529 39Z 0.8534
530 JBZ 0.8533
531 NDD 0.8519
532 J8D 0.8514
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YVM; Ligand: TMG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1yvm.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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