Receptor
PDB id Resolution Class Description Source Keywords
2Q92 1.9 Å EC: 3.4.11.18 E. COLI METHIONINE AMINOPEPTIDASE MN-FORM WITH INHIBITOR B23 ESCHERICHIA COLI AMINOPEPTIDASE HYDROLASE DINUCLEAR MN(II)-FORM ENZYME- INHIBITOR COMPLEX METALLOENZYME
Ref.: STRUCTURAL ANALYSIS OF INHIBITION OF E. COLI METHIONINE AMINOPEPTIDASE: IMPLICATION OF LOOP FLEXIBILITY IN SELECTIVE INHIBITION OF BACTERIAL ENZYMES. BMC STRUCT.BIOL. V. 7 84 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
B23 A:400;
 Valid;
 none;
 ic50 = 1.1 uM
233.177 C11 H7 N O5 c1ccc...
MN A:300;
A:301;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
54.938 Mn [Mn+2...
NA A:500;
 Part of Protein;
 none;
 submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YVM 1.6 Å EC: 3.4.11.18 E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH THIABENDAZOLE ESCHERICHIA COLI HYDROLASE(ALPHA-AMINOACYLPEPTIDE) METAL COMPLEX THIABENDAZOLE METHIONINE AMINOPEPTIDASE INHIBITOR
Ref.: METAL IONS AS COFACTORS FOR THE BINDING OF INHIBITORS TO METHIONINE AMINOPEPTIDASE: A CRITICAL VIEW OF THE RELEVANCE OF IN VITRO METALLOENZYME ASSAYS. ANGEW.CHEM.INT.ED.ENGL. V. 44 3620 2005
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
70% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
50% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2NQ6 ic50 = 1.5 uM HM4 C14 H16 N4 O3 S CC(C)(C)OC....
2 4U69 Ki = 54.8 uM Q07 C6 H16 N O3 P CCC[C@H](C....
3 2G6P ic50 = 0.6 uM HM2 C18 H17 Cl N4 Cc1c(c(nc(....
4 4U73 Ki = 6.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
5 4IKT ic50 = 0.67 uM TFV C18 H16 Cl F3 N6 Cc1c(c(nc(....
6 4U6Z Ki = 3.9 uM Q07 C6 H16 N O3 P CCC[C@H](C....
7 4U70 Ki = 9.5 uM Q04 C8 H18 N O3 P C1CCC(CC1)....
8 4FLI ic50 = 3.59 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
9 4U6C Ki = 9.9 uM Q06 C8 H18 N O3 P C1CCC(C1)C....
10 4IKR ic50 = 0.59 uM PVP C16 H20 Cl N5 O Cc1c(c(nc(....
11 4FLK ic50 = 5.58 uM Y10 C21 H31 N O5 CC(C)(C)/C....
12 4IKU ic50 = 1.79 uM SHX C19 H18 Cl N5 O Cc1c(c(nc(....
13 2NQ7 ic50 = 2.9 uM HM5 C14 H16 N4 O2 S CC(C)(C)C(....
14 4FLL ic50 = 5.14 uM YZ6 C25 H35 N O6 CC(C)(C)/C....
15 4U71 Ki = 6 uM Q03 C7 H16 N O3 P C1CCC(CC1)....
16 4HXX - 1AY C28 H29 Cl2 N5 Cc1c(c(nc(....
17 4IKS ic50 = 7.23 uM TFD C18 H16 Cl F3 N6 Cc1c(c(nc(....
18 4U6E Ki = 111.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
19 4U1B Ki = 4.9 uM Q08 C8 H20 N O3 P CCCC(CCC)[....
20 4FLJ ic50 = 7.45 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
21 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
22 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
23 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
24 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
25 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
26 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
27 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
28 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
29 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
30 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
31 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
32 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
33 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
34 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
35 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
36 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
37 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
38 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
39 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
40 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
41 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
42 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
43 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
44 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
45 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
46 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
47 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
48 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
49 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
50 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
51 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
52 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
53 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
54 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
55 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
56 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
57 4IU6 - FZ1 C24 H23 N5 O COc1ccc(cc....
58 1QXZ ic50 = 19 uM M3C C8 H14 N2 O2 S2 CSCC[C@@H]....
59 1QXY ic50 = 16 uM M2C C10 H16 N2 O2 S CSCC[C@@H]....
60 1QXW ic50 = 7 uM M1C C10 H22 N2 O2 CCCC[C@@H]....
61 3IU9 ic50 = 0.24 uM T07 C9 H8 Cl2 N4 S c1cc(c(cc1....
62 3IU7 ic50 = 16 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
63 3PKE - Y10 C21 H31 N O5 CC(C)(C)/C....
64 3PKB ic50 = 0.62 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
65 3PKA ic50 = 0.54 uM Y02 C23 H37 N O6 Cc1cc(c(c(....
66 3PKC ic50 = 0.96 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
67 3IU8 ic50 = 0.58 uM T03 C9 H8 F N3 S c1cc(ccc1C....
68 3PKD ic50 = 0.76 uM Y10 C21 H31 N O5 CC(C)(C)/C....
69 1YJ3 - MET C5 H11 N O2 S CSCC[C@@H]....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: B23; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 B23 1 1
2 A05 0.466667 0.893617
Similar Ligands (3D)
Ligand no: 1; Ligand: B23; Similar ligands found: 347
No: Ligand Similarity coefficient
1 B21 0.9631
2 FC3 0.9453
3 IKY 0.9448
4 EAJ 0.9430
5 FC2 0.9406
6 FCD 0.9390
7 3B4 0.9321
8 TJM 0.9316
9 YE6 0.9314
10 AJD 0.9294
11 PQT 0.9285
12 Q2R 0.9189
13 ELH 0.9164
14 AUV 0.9161
15 A04 0.9147
16 BIE 0.9144
17 AKD 0.9124
18 HA6 0.9098
19 Q5M 0.9089
20 6HP 0.9089
21 5E4 0.9083
22 Q9T 0.9081
23 5V7 0.9079
24 F5C 0.9068
25 U19 0.9060
26 5WT 0.9049
27 774 0.9046
28 3IL 0.9038
29 OX2 0.9034
30 9GP 0.9028
31 4GU 0.9024
32 5P3 0.9020
33 WVV 0.9017
34 3Y7 0.9016
35 DXK 0.9013
36 TOM 0.9013
37 WL3 0.9007
38 ZIP 0.9004
39 4GP 0.9003
40 12R 0.9001
41 M02 0.8999
42 9F8 0.8998
43 5C1 0.8991
44 CX4 0.8990
45 2JK 0.8989
46 6J3 0.8986
47 7L4 0.8986
48 YE7 0.8986
49 LLG 0.8980
50 KLV 0.8973
51 26C 0.8970
52 CHQ 0.8970
53 1ER 0.8967
54 QUB 0.8965
55 RUG 0.8963
56 WOE 0.8963
57 6GP 0.8962
58 EYA 0.8960
59 3WJ 0.8959
60 67Y 0.8959
61 G6P 0.8954
62 IOP 0.8952
63 1SF 0.8951
64 5WS 0.8949
65 W29 0.8947
66 L21 0.8946
67 3D8 0.8941
68 OSB 0.8938
69 C09 0.8933
70 BGU 0.8932
71 8UY 0.8930
72 ONZ 0.8929
73 NTF 0.8929
74 TOH 0.8921
75 MXD 0.8920
76 H4B 0.8920
77 78P 0.8912
78 CR1 0.8911
79 F40 0.8910
80 EYM 0.8907
81 D80 0.8904
82 8G6 0.8904
83 4A1 0.8898
84 G14 0.8897
85 PVQ 0.8896
86 PVK 0.8895
87 H35 0.8891
88 CMG 0.8890
89 IBC 0.8890
90 B4O 0.8889
91 6J9 0.8889
92 MBP 0.8888
93 57D 0.8887
94 AZC 0.8886
95 BQ5 0.8883
96 4F8 0.8880
97 CGW 0.8879
98 AH9 0.8878
99 6QT 0.8877
100 2GQ 0.8871
101 V1T 0.8871
102 MUR 0.8868
103 AMR 0.8865
104 ALR 0.8862
105 OCZ 0.8861
106 BBY 0.8860
107 AVX 0.8859
108 FER 0.8859
109 I59 0.8859
110 JFS 0.8848
111 HHV 0.8845
112 GI4 0.8845
113 P4L 0.8845
114 ZEA 0.8844
115 JP2 0.8843
116 KW7 0.8842
117 FUZ 0.8839
118 FNA 0.8837
119 BDI 0.8832
120 2WU 0.8831
121 TI7 0.8824
122 CG8 0.8824
123 1QV 0.8823
124 OUB 0.8821
125 BG6 0.8818
126 CTN 0.8816
127 P83 0.8816
128 55D 0.8813
129 CPW 0.8813
130 0SY 0.8813
131 KYN 0.8812
132 JF8 0.8811
133 XFE 0.8809
134 8HH 0.8808
135 TRP 0.8808
136 27M 0.8808
137 YEX 0.8808
138 BPS 0.8807
139 PYU 0.8807
140 DBQ 0.8806
141 9BF 0.8804
142 C9E 0.8803
143 2KU 0.8803
144 P9I 0.8803
145 PIR 0.8802
146 22L 0.8800
147 4R1 0.8800
148 IQQ 0.8800
149 LJ3 0.8800
150 A4G 0.8798
151 7M5 0.8796
152 ODK 0.8796
153 5WN 0.8791
154 D87 0.8790
155 2LX 0.8789
156 4FF 0.8789
157 O2Y 0.8789
158 4G2 0.8787
159 S98 0.8786
160 LTN 0.8780
161 CJZ 0.8780
162 NE2 0.8780
163 BZE 0.8780
164 7I2 0.8780
165 PMP 0.8778
166 MPP 0.8778
167 HRM 0.8777
168 A4V 0.8777
169 L13 0.8777
170 AC2 0.8775
171 Z15 0.8772
172 LOT 0.8772
173 GPK 0.8771
174 1V1 0.8770
175 1FL 0.8770
176 5NN 0.8770
177 20D 0.8767
178 H7S 0.8765
179 Z57 0.8764
180 XG1 0.8762
181 9UL 0.8762
182 H70 0.8760
183 1A7 0.8760
184 A73 0.8758
185 MR6 0.8758
186 R4E 0.8755
187 EAT 0.8751
188 URI 0.8750
189 IMK 0.8749
190 5AD 0.8749
191 DKZ 0.8747
192 78U 0.8747
193 2GD 0.8746
194 A7K 0.8744
195 89J 0.8743
196 5E5 0.8742
197 PLP 0.8742
198 3GX 0.8739
199 L5D 0.8735
200 XQI 0.8733
201 DKX 0.8732
202 GI2 0.8732
203 CJB 0.8731
204 DNQ 0.8729
205 30G 0.8729
206 JTF 0.8728
207 SXX 0.8727
208 G1P 0.8725
209 HBO 0.8724
210 X11 0.8724
211 53X 0.8723
212 5OF 0.8723
213 5FL 0.8722
214 CMU 0.8721
215 NE1 0.8718
216 BHS 0.8718
217 96Z 0.8718
218 BGP 0.8716
219 N2M 0.8715
220 PXP 0.8715
221 CWE 0.8715
222 ZRL 0.8713
223 ADN 0.8713
224 5F8 0.8710
225 78Y 0.8710
226 THM 0.8709
227 B61 0.8708
228 CC5 0.8708
229 6TJ 0.8707
230 47V 0.8705
231 6ZW 0.8705
232 QIF 0.8703
233 2QU 0.8703
234 9JT 0.8702
235 KP2 0.8700
236 A1Y 0.8700
237 EZN 0.8696
238 BPY 0.8694
239 25F 0.8694
240 DFL 0.8694
241 UN4 0.8693
242 FHI 0.8690
243 GNV 0.8688
244 LR2 0.8685
245 M6P 0.8685
246 56N 0.8682
247 4NR 0.8680
248 64E 0.8680
249 AVA 0.8677
250 JR2 0.8676
251 IDZ 0.8673
252 NQH 0.8672
253 4EU 0.8672
254 L1T 0.8672
255 K80 0.8671
256 7VF 0.8670
257 Q0K 0.8670
258 H2B 0.8670
259 DK4 0.8670
260 1V3 0.8669
261 GI3 0.8669
262 M3W 0.8666
263 GLP 0.8666
264 GPU 0.8664
265 S60 0.8660
266 TIZ 0.8659
267 49N 0.8658
268 X0W 0.8657
269 6JO 0.8656
270 DDC 0.8655
271 ZSP 0.8655
272 B2T 0.8653
273 PCQ 0.8653
274 HBI 0.8651
275 CKI 0.8650
276 BIO 0.8648
277 N7I 0.8647
278 7M2 0.8645
279 K48 0.8643
280 NHT 0.8641
281 AH6 0.8641
282 17C 0.8640
283 7MX 0.8640
284 ZYW 0.8640
285 PBQ 0.8640
286 3JC 0.8640
287 1XS 0.8638
288 8W9 0.8637
289 6JM 0.8633
290 2LT 0.8633
291 49O 0.8629
292 N91 0.8628
293 SYE 0.8627
294 ZYQ 0.8625
295 9X5 0.8624
296 LFQ 0.8623
297 PLR 0.8622
298 CX6 0.8622
299 X29 0.8622
300 3VX 0.8620
301 ITE 0.8620
302 NAR 0.8619
303 ZRK 0.8617
304 8WZ 0.8615
305 IA2 0.8614
306 GPQ 0.8613
307 S8D 0.8612
308 LP8 0.8611
309 IQW 0.8610
310 CDY 0.8608
311 WCU 0.8607
312 XIF XYP 0.8602
313 GAT 0.8601
314 DK1 0.8600
315 28B 0.8592
316 1V4 0.8586
317 AB3 0.8585
318 6DQ 0.8583
319 0DF 0.8580
320 6XI 0.8578
321 DUR 0.8575
322 XI7 0.8574
323 F2W 0.8573
324 XYP XIF 0.8572
325 MOK 0.8571
326 5AE 0.8570
327 KMP 0.8570
328 R9Y 0.8569
329 NPL 0.8566
330 8D6 0.8564
331 5TY 0.8563
332 AGI 0.8562
333 LJ4 0.8560
334 5F5 0.8560
335 TB8 0.8554
336 DCZ 0.8554
337 CDJ 0.8553
338 BP7 0.8551
339 4I5 0.8545
340 FSU 0.8545
341 2QV 0.8539
342 BPU 0.8532
343 X48 0.8530
344 PIQ 0.8526
345 977 0.8520
346 3WL 0.8520
347 FF2 0.8512
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YVM; Ligand: TMG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1yvm.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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