Receptor
PDB id Resolution Class Description Source Keywords
2GG7 1.12 Å EC: 3.4.11.18 NOVEL BACTERIAL METHIONINE AMINOPEPTIDASE INHIBITORS ESCHERICHIA COLI K12 METHIONINE AMINO PEPTIDASE PITA-BREAD FOLD MAP INHIBITOR ANTIBACTERIAL HYDROLASE
Ref.: SERENDIPITOUS DISCOVERY OF NOVEL BACTERIAL METHIONINE AMINOPEPTIDASE INHIBITORS. PROTEINS V. 66 538 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CO A:301;
A:302;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
58.933 Co [Co+2...
NA A:703;
 Part of Protein;
 none;
 submit data
22.99 Na [Na+]
U14 A:701;
 Valid;
 none;
 ic50 = 1.75 uM
244.21 C10 H8 N6 O2 [H]/N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YVM 1.6 Å EC: 3.4.11.18 E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH THIABENDAZOLE ESCHERICHIA COLI HYDROLASE(ALPHA-AMINOACYLPEPTIDE) METAL COMPLEX THIABENDAZOLE METHIONINE AMINOPEPTIDASE INHIBITOR
Ref.: METAL IONS AS COFACTORS FOR THE BINDING OF INHIBITORS TO METHIONINE AMINOPEPTIDASE: A CRITICAL VIEW OF THE RELEVANCE OF IN VITRO METALLOENZYME ASSAYS. ANGEW.CHEM.INT.ED.ENGL. V. 44 3620 2005
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
70% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
50% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2NQ6 ic50 = 1.5 uM HM4 C14 H16 N4 O3 S CC(C)(C)OC....
2 4U69 Ki = 54.8 uM Q07 C6 H16 N O3 P CCC[C@H](C....
3 2G6P ic50 = 0.6 uM HM2 C18 H17 Cl N4 Cc1c(c(nc(....
4 4U73 Ki = 6.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
5 4IKT ic50 = 0.67 uM TFV C18 H16 Cl F3 N6 Cc1c(c(nc(....
6 4U6Z Ki = 3.9 uM Q07 C6 H16 N O3 P CCC[C@H](C....
7 4U70 Ki = 9.5 uM Q04 C8 H18 N O3 P C1CCC(CC1)....
8 4FLI ic50 = 3.59 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
9 4U6C Ki = 9.9 uM Q06 C8 H18 N O3 P C1CCC(C1)C....
10 4IKR ic50 = 0.59 uM PVP C16 H20 Cl N5 O Cc1c(c(nc(....
11 4FLK ic50 = 5.58 uM Y10 C21 H31 N O5 CC(C)(C)/C....
12 4IKU ic50 = 1.79 uM SHX C19 H18 Cl N5 O Cc1c(c(nc(....
13 2NQ7 ic50 = 2.9 uM HM5 C14 H16 N4 O2 S CC(C)(C)C(....
14 4FLL ic50 = 5.14 uM YZ6 C25 H35 N O6 CC(C)(C)/C....
15 4U71 Ki = 6 uM Q03 C7 H16 N O3 P C1CCC(CC1)....
16 4HXX - 1AY C28 H29 Cl2 N5 Cc1c(c(nc(....
17 4IKS ic50 = 7.23 uM TFD C18 H16 Cl F3 N6 Cc1c(c(nc(....
18 4U6E Ki = 111.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
19 4U1B Ki = 4.9 uM Q08 C8 H20 N O3 P CCCC(CCC)[....
20 4FLJ ic50 = 7.45 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
21 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
22 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
23 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
24 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
25 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
26 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
27 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
28 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
29 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
30 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
31 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
32 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
33 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
34 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
35 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
36 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
37 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
38 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
39 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
40 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
41 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
42 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
43 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
44 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
45 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
46 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
47 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
48 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
49 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
50 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
51 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
52 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
53 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
54 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
55 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
56 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
57 4IU6 - FZ1 C24 H23 N5 O COc1ccc(cc....
58 1QXZ ic50 = 19 uM M3C C8 H14 N2 O2 S2 CSCC[C@@H]....
59 1QXY ic50 = 16 uM M2C C10 H16 N2 O2 S CSCC[C@@H]....
60 1QXW ic50 = 7 uM M1C C10 H22 N2 O2 CCCC[C@@H]....
61 3IU9 ic50 = 0.24 uM T07 C9 H8 Cl2 N4 S c1cc(c(cc1....
62 3IU7 ic50 = 16 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
63 3PKE - Y10 C21 H31 N O5 CC(C)(C)/C....
64 3PKB ic50 = 0.62 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
65 3PKA ic50 = 0.54 uM Y02 C23 H37 N O6 Cc1cc(c(c(....
66 3PKC ic50 = 0.96 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
67 3IU8 ic50 = 0.58 uM T03 C9 H8 F N3 S c1cc(ccc1C....
68 3PKD ic50 = 0.76 uM Y10 C21 H31 N O5 CC(C)(C)/C....
69 1YJ3 - MET C5 H11 N O2 S CSCC[C@@H]....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: U14; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 U14 1 1
2 U12 0.540984 0.765957
3 U13 0.440678 0.782609
Similar Ligands (3D)
Ligand no: 1; Ligand: U14; Similar ligands found: 402
No: Ligand Similarity coefficient
1 6FX 0.9459
2 T21 0.9447
3 28A 0.9445
4 IDZ 0.9441
5 801 0.9436
6 7G2 0.9415
7 Q2S 0.9413
8 A45 0.9410
9 4RG 0.9407
10 1V8 0.9362
11 1XS 0.9361
12 Q92 0.9319
13 TVC 0.9297
14 Q4G 0.9286
15 47V 0.9268
16 MT6 0.9245
17 WG8 0.9239
18 122 0.9232
19 BMC 0.9209
20 C0V 0.9200
21 121 0.9183
22 CR4 0.9179
23 BMZ 0.9176
24 GW9 0.9172
25 38E 0.9161
26 120 0.9160
27 JSX 0.9159
28 0DJ 0.9156
29 L5D 0.9156
30 6F3 0.9154
31 97K 0.9146
32 20D 0.9141
33 NZ4 0.9137
34 XYP XIM 0.9132
35 B4L 0.9129
36 9RM 0.9119
37 0NJ 0.9118
38 205 0.9114
39 LU2 0.9114
40 6BK 0.9112
41 RGK 0.9110
42 4AU 0.9108
43 Z3R 0.9105
44 NKI 0.9103
45 IQQ 0.9103
46 NFL 0.9103
47 581 0.9102
48 5ER 0.9098
49 1V1 0.9097
50 4GU 0.9085
51 C4E 0.9084
52 A73 0.9080
53 S1D 0.9080
54 5F8 0.9076
55 DFL 0.9074
56 AV4 0.9072
57 LR2 0.9070
58 U4J 0.9070
59 EEY 0.9068
60 28B 0.9062
61 6XC 0.9062
62 A63 0.9061
63 1FL 0.9060
64 0UL 0.9060
65 8KW 0.9050
66 NU3 0.9048
67 272 0.9041
68 XEV 0.9041
69 X2M 0.9040
70 124 0.9039
71 3Q0 0.9038
72 9CE 0.9032
73 2QU 0.9028
74 BBP 0.9025
75 LFK 0.9023
76 245 0.9021
77 5C1 0.9017
78 4FF 0.9013
79 9JT 0.9011
80 LZ7 0.9009
81 ESJ 0.9007
82 08C 0.9004
83 E2N 0.9004
84 QKU 0.9002
85 AV7 0.9002
86 BVS 0.9001
87 WLH 0.9001
88 MR4 0.8999
89 A9B 0.8998
90 7FZ 0.8993
91 1V3 0.8992
92 5E5 0.8992
93 VBC 0.8991
94 PIQ 0.8989
95 XIL 0.8986
96 2QV 0.8985
97 3D8 0.8985
98 GLA BEZ 0.8983
99 338 0.8983
100 TVZ 0.8983
101 GAA 0.8982
102 IK1 0.8977
103 ZRK 0.8975
104 JCQ 0.8971
105 RK4 0.8970
106 18E 0.8969
107 4G2 0.8968
108 FSE 0.8966
109 4ZF 0.8964
110 6JM 0.8961
111 3F4 0.8958
112 1HP 0.8958
113 EMU 0.8957
114 IIH 0.8956
115 SZ5 0.8955
116 XYP XYP 0.8955
117 5VU 0.8955
118 M3W 0.8954
119 P4T 0.8954
120 8M5 0.8952
121 MR6 0.8951
122 JWS 0.8949
123 2D2 0.8946
124 QUE 0.8946
125 6C8 0.8945
126 LI7 0.8945
127 F40 0.8944
128 AVA 0.8941
129 NOC 0.8939
130 39R 0.8938
131 E9L 0.8938
132 ZRL 0.8937
133 BZC 0.8934
134 1V4 0.8933
135 BXS 0.8933
136 25F 0.8931
137 68C 0.8931
138 IMK 0.8927
139 F18 0.8927
140 7L4 0.8926
141 0SY 0.8925
142 L3L 0.8925
143 LOX XYP 0.8923
144 1UZ 0.8921
145 SSY 0.8920
146 M83 0.8919
147 AGI 0.8918
148 5TO 0.8918
149 27F 0.8917
150 0DF 0.8915
151 4YE 0.8912
152 6DQ 0.8912
153 1Q4 0.8911
154 NIY 0.8911
155 5WK 0.8909
156 YIP 0.8909
157 6H2 0.8908
158 108 0.8908
159 4K2 0.8907
160 MTA 0.8906
161 H35 0.8903
162 FHV 0.8902
163 CZ0 0.8901
164 MHB 0.8901
165 GQZ 0.8900
166 7EH 0.8899
167 DXK 0.8897
168 0X2 0.8893
169 FX5 0.8892
170 ARJ 0.8891
171 DS8 0.8889
172 G30 0.8889
173 UKV 0.8886
174 FLF 0.8885
175 QS4 0.8885
176 II4 0.8883
177 WCU 0.8882
178 V2Z 0.8882
179 B06 0.8881
180 5FL 0.8881
181 JF5 0.8880
182 DFV 0.8879
183 NIF 0.8878
184 397 0.8874
185 57D 0.8873
186 KTM 0.8871
187 IPJ 0.8871
188 OLU 0.8871
189 STL 0.8868
190 6QT 0.8868
191 3JC 0.8867
192 CJZ 0.8866
193 VM7 0.8865
194 EFX 0.8865
195 H2W 0.8864
196 U98 0.8862
197 CDJ 0.8861
198 1DR 0.8859
199 1V0 0.8857
200 HH6 0.8856
201 ISX 0.8855
202 W8L 0.8855
203 5NN 0.8854
204 ZEA 0.8850
205 ZEZ 0.8849
206 KWB 0.8848
207 S0D 0.8848
208 IW1 0.8845
209 MR5 0.8845
210 T34 0.8845
211 XDL XYP 0.8844
212 5B2 0.8844
213 UN4 0.8843
214 OUA 0.8842
215 27M 0.8841
216 UV4 0.8839
217 CMG 0.8836
218 5P3 0.8836
219 5WW 0.8835
220 D25 0.8834
221 T5J 0.8834
222 UN3 0.8831
223 P4L 0.8830
224 1UT 0.8829
225 OUG 0.8826
226 6TJ 0.8825
227 H32 0.8825
228 XYP XDN 0.8820
229 RF2 0.8820
230 NFZ 0.8818
231 3GX 0.8816
232 3SU 0.8816
233 MYC 0.8815
234 EDG AHR 0.8813
235 LUM 0.8813
236 VT3 0.8811
237 NAR 0.8804
238 JRO 0.8799
239 6FG 0.8797
240 802 0.8795
241 15Q 0.8794
242 IEE 0.8791
243 SU9 0.8789
244 53X 0.8787
245 XDN XYP 0.8786
246 AUV 0.8784
247 1UR 0.8783
248 S0A 0.8783
249 EP4 0.8783
250 78Y 0.8779
251 0LO 0.8779
252 0K7 0.8778
253 A51 0.8777
254 5P7 0.8773
255 TH1 0.8772
256 3WL 0.8771
257 6JO 0.8770
258 4YF 0.8769
259 A6W 0.8766
260 AHR AHR 0.8765
261 0MB 0.8764
262 F36 0.8763
263 Q7U 0.8762
264 833 0.8761
265 797 0.8760
266 NAB 0.8760
267 0XR 0.8759
268 DX2 0.8759
269 3MI 0.8755
270 FY8 0.8755
271 ERZ 0.8752
272 3WK 0.8750
273 SNJ 0.8748
274 4L2 0.8747
275 BBY 0.8743
276 BSU 0.8743
277 CBE 0.8741
278 5S9 0.8740
279 6JP 0.8740
280 BRY 0.8738
281 XYS XYS 0.8738
282 5TZ 0.8735
283 XYS XYP 0.8735
284 4CN 0.8734
285 A05 0.8734
286 40N 0.8733
287 1SF 0.8732
288 A64 0.8731
289 JMG 0.8731
290 8CC 0.8729
291 KWV 0.8727
292 LIG 0.8726
293 EAT 0.8725
294 G2V 0.8724
295 4HG 0.8724
296 BZM 0.8724
297 YE6 0.8723
298 6C5 0.8719
299 DH2 0.8719
300 HHB 0.8716
301 D8B 0.8715
302 6WU 0.8714
303 STV 0.8706
304 3VQ 0.8706
305 AJG 0.8706
306 AOY 0.8705
307 68B 0.8704
308 JBB 0.8703
309 PZX 0.8703
310 2JX 0.8701
311 WDW 0.8699
312 0ON 0.8699
313 IW2 0.8699
314 H0V 0.8698
315 1AJ 0.8695
316 T61 0.8694
317 AO 0.8693
318 X6W 0.8691
319 CWE 0.8690
320 2UV 0.8686
321 CC6 0.8684
322 K4T 0.8682
323 PCQ 0.8682
324 DDC 0.8681
325 6MW 0.8681
326 JF8 0.8680
327 907 0.8680
328 LJ5 0.8678
329 91F 0.8676
330 QUG 0.8675
331 90G 0.8674
332 041 0.8673
333 CFK 0.8673
334 ZAR 0.8673
335 6C4 0.8672
336 SGW 0.8672
337 36K 0.8666
338 1EL 0.8665
339 BGC BGC 0.8664
340 5R9 0.8663
341 SJR 0.8662
342 AVX 0.8662
343 TCR 0.8661
344 LC1 0.8660
345 2PW 0.8660
346 FER 0.8658
347 JVD 0.8654
348 HWB 0.8652
349 NRA 0.8650
350 5KN 0.8650
351 6C9 0.8646
352 7KE 0.8643
353 XI7 0.8642
354 N9M 0.8641
355 RKV 0.8639
356 ZZA 0.8637
357 FZB 0.8637
358 RCV 0.8635
359 TPM 0.8633
360 JL7 0.8632
361 4B8 0.8632
362 3WO 0.8630
363 3WN 0.8630
364 1Q2 0.8629
365 51Y 0.8626
366 YE7 0.8622
367 39Z 0.8620
368 HRD 0.8619
369 MHD GAL 0.8619
370 GOW 0.8618
371 4Z1 0.8617
372 PRL 0.8616
373 VXP 0.8615
374 DN8 0.8614
375 J8D 0.8612
376 4UM 0.8612
377 2J1 0.8609
378 NW1 0.8608
379 3CX 0.8601
380 RAY 0.8600
381 6T5 0.8596
382 LJ2 0.8594
383 WA2 0.8594
384 103 0.8593
385 P93 0.8591
386 HRM 0.8585
387 O53 0.8584
388 LJ1 0.8581
389 FQX 0.8570
390 78P 0.8563
391 TIZ 0.8560
392 3Q1 0.8559
393 L1T 0.8557
394 IOP 0.8543
395 LRW 0.8542
396 UAY 0.8531
397 JTF 0.8529
398 4P9 0.8526
399 GUS 0.8525
400 DE7 0.8524
401 3TI 0.8523
402 QR2 0.8507
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YVM; Ligand: TMG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1yvm.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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