Receptor
PDB id Resolution Class Description Source Keywords
2X2F 2 Å EC: 3.6.5.5 DYNAMIN 1 GTPASE DIMER, SHORT AXIS FORM HOMO SAPIENS NITRATION HYDROLASE MEMBRANE FISSION NUCLEOTIDE-BINDING ENDOCYTOSIS MOTOR PROTEIN
Ref.: G DOMAIN DIMERIZATION CONTROLS DYNAMIN'S ASSEMBLY-STIMULATED GTPASE ACTIVITY. NATURE V. 465 435 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP ALF D:1746;
A:1747;
Valid;
Valid;
none;
none;
submit data
543.152 n/a [P+](...
MG A:1749;
D:1748;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
NA A:1750;
D:1749;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2X2E 2 Å EC: 3.6.5.5 DYNAMIN GTPASE DIMER, LONG AXIS FORM HOMO SAPIENS NITRATION HYDROLASE MEMBRANE FISSION NUCLEOTIDE-BINDING ENDOCYTOSIS MOTOR PROTEIN
Ref.: G DOMAIN DIMERIZATION CONTROLS DYNAMIN'S ASSEMBLY-STIMULATED GTPASE ACTIVITY. NATURE V. 465 435 2010
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2X2F - GDP ALF n/a n/a
2 5D3Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3ZYC - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
4 2X2E - GDP ALF n/a n/a
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2X2F - GDP ALF n/a n/a
2 5D3Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3ZYC - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
4 2X2E - GDP ALF n/a n/a
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 3T34 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2X2F - GDP ALF n/a n/a
3 5D3Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 3ZYC - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
5 2X2E - GDP ALF n/a n/a
6 4P4T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4H1V - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4H1U - FLC C6 H5 O7 C(C(=O)[O-....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP ALF; Similar ligands found: 110
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP ALF 1 1
2 ALF 5GP 0.857143 1
3 GTP MG 0.806818 0.91358
4 GDP MG 0.802326 0.91358
5 GDP AF3 0.8 1
6 GDP BEF 0.793103 0.938272
7 BEF GDP 0.786517 0.950617
8 GDP 7MG 0.71 0.879518
9 5GP 0.701149 0.9
10 G 0.701149 0.9
11 GDP 0.7 0.888889
12 GP3 0.688889 0.86747
13 GNH 0.673913 0.878049
14 GCP G 0.666667 0.901235
15 G G 0.666667 0.901235
16 GP2 0.663043 0.857143
17 GTP 0.659574 0.888889
18 G1R 0.652632 0.878049
19 GCP 0.652632 0.86747
20 G2P 0.645833 0.857143
21 GSP 0.645833 0.847059
22 GNP 0.645833 0.86747
23 GMV 0.642105 0.890244
24 GAV 0.632653 0.857143
25 G2R 0.613861 0.857143
26 GMP 0.593023 0.802469
27 GPG 0.592233 0.857143
28 G1R G1R 0.591667 0.869048
29 6CK 0.588785 0.903614
30 PGD O 0.586777 0.784946
31 Y9Z 0.584906 0.808989
32 GDC 0.584906 0.857143
33 GDD 0.584906 0.857143
34 GKE 0.584906 0.857143
35 GTG 0.579439 0.858824
36 GFB 0.579439 0.857143
37 GDR 0.579439 0.857143
38 I2C FE2 CMO CMO 0.576271 0.804348
39 YGP 0.575472 0.827586
40 G3A 0.574074 0.86747
41 G5P 0.568807 0.86747
42 ADP ALF 0.565657 0.9125
43 ALF ADP 0.565657 0.9125
44 JB2 0.563636 0.857143
45 GKD 0.563636 0.857143
46 U A G G 0.559322 0.901235
47 GDX 0.558559 0.86747
48 GPD 0.558559 0.827586
49 G A A A 0.550847 0.890244
50 G3D 0.54902 0.876543
51 FEG 0.543103 0.808989
52 G4P 0.538462 0.876543
53 ZGP 0.538462 0.8
54 3GP 0.536842 0.864198
55 JB3 0.534483 0.847059
56 NGD 0.529915 0.879518
57 0O2 0.518519 0.876543
58 U2G 0.516949 0.837209
59 2MD 0.516667 0.8
60 CAG 0.516393 0.811111
61 G G U 0.508772 0.878049
62 CG2 0.508333 0.837209
63 G C 0.504132 0.869048
64 MGD 0.504065 0.8
65 MD1 0.5 0.8
66 DBG 0.492188 0.847059
67 2GP 0.489796 0.853659
68 PGD 0.488189 0.827586
69 U G A 0.481752 0.858824
70 TPG 0.48062 0.757895
71 FE9 0.480315 0.755102
72 GPX 0.477064 0.841463
73 DGI 0.471154 0.823529
74 G G G C 0.46875 0.858824
75 G G G RPC 0.467742 0.845238
76 A G C C 0.465116 0.879518
77 GH3 0.458716 0.865854
78 G4M 0.456522 0.791209
79 DG 0.455446 0.833333
80 DGP 0.455446 0.833333
81 BGO 0.455285 0.825581
82 DGT 0.453704 0.823529
83 APC G U 0.453125 0.855422
84 DG DG 0.451327 0.837209
85 G C C C 0.451128 0.869048
86 P2G 0.45098 0.807229
87 P1G 0.442308 0.797619
88 ADP PO3 0.438095 0.8375
89 IDP 0.438095 0.864198
90 ATP MG 0.433962 0.829268
91 GGM 0.433071 0.806818
92 A G U 0.432624 0.858824
93 IMP 0.431373 0.875
94 AF3 ADP 3PG 0.430894 0.902439
95 G1G 0.427481 0.848837
96 ADP MG 0.423077 0.829268
97 ADP BEF 0.419048 0.853659
98 BEF ADP 0.419048 0.853659
99 ADP VO4 0.418182 0.829268
100 VO4 ADP 0.418182 0.829268
101 G U34 0.417323 0.858824
102 5GP 5GP 0.416667 0.851852
103 ALF GDP 0.414414 0.936709
104 G7M 0.413462 0.890244
105 GPC 0.412214 0.872093
106 SGP 0.409524 0.758621
107 C2E 0.407407 0.841463
108 PCG 0.407407 0.851852
109 35G 0.407407 0.851852
110 OMC OMU OMG OMG U 0.406897 0.83908
Similar Binding Sites (Proteins are less than 50% similar to leader)
Feedback