Receptor
PDB id Resolution Class Description Source Keywords
4WUA 2 Å EC: 2.7.1.37 CRYSTAL STRUCTURE OF HUMAN SRPK1 COMPLEXED TO AN INHIBITOR S HOMO SAPIENS PROTEIN KINASE KINASE-INHIBITOR COMPLEX PRE-MRNA SPLICINGBINDING TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: IDENTIFICATION OF A DUAL INHIBITOR OF SRPK1 AND CK2 ATTENUATES PATHOLOGICAL ANGIOGENESIS OF MACULAR DEG IN MICE MOL.PHARMACOL. V. 88 316 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
3UL A:701;
Valid;
none;
submit data
349.35 C18 H18 F3 N3 O c1cc(...
CIT A:702;
Invalid;
none;
submit data
192.124 C6 H8 O7 C(C(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5MY8 1.7 Å EC: 2.7.1.37 CRYSTAL STRUCTURE OF SRPK1 IN COMPLEX WITH SPHINX31 HOMO SAPIENS TRANSFERASE SPLICING KINASE INHIBITOR STRUCTURAL GENOMICSSTRUCTURAL GENOMICS CONSORTIUM SGC
Ref.: DEVELOPMENT OF POTENT, SELECTIVE SRPK1 INHIBITORS A POTENTIAL TOPICAL THERAPEUTICS FOR NEOVASCULAR EYE ACS CHEM. BIOL. V. 12 825 2017
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 5MXX ic50 = 31 nM W4A C18 H20 F3 N3 O2 Cc1ccc(o1)....
2 1WBP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5MY8 ic50 = 6 nM RXZ C27 H24 F3 N5 O2 c1ccnc(c1)....
4 4WUA - 3UL C18 H18 F3 N3 O c1cc(c(cc1....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 15 families.
1 5MXX ic50 = 31 nM W4A C18 H20 F3 N3 O2 Cc1ccc(o1)....
2 1WBP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5MY8 ic50 = 6 nM RXZ C27 H24 F3 N5 O2 c1ccnc(c1)....
4 4WUA - 3UL C18 H18 F3 N3 O c1cc(c(cc1....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 12 families.
1 5MXX ic50 = 31 nM W4A C18 H20 F3 N3 O2 Cc1ccc(o1)....
2 1WBP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5MY8 ic50 = 6 nM RXZ C27 H24 F3 N5 O2 c1ccnc(c1)....
4 4WUA - 3UL C18 H18 F3 N3 O c1cc(c(cc1....
5 1Q99 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
6 2JD5 - ARG GLU ARG SER PRO THR ARG n/a n/a
7 1Q8Y - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
8 1Q97 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 3UL; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 3UL 1 1
2 RXZ 0.453608 0.824561
3 W4A 0.439024 0.754098
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5MY8; Ligand: RXZ; Similar sites found: 378
This union binding pocket(no: 1) in the query (biounit: 5my8.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2RIF AMP 0.01552 0.40323 None
2 3SJK LYS PRO VAL LEU ARG THR ALA 0.02116 0.41686 1.05263
3 3ZJX BOG 0.001072 0.48271 1.38408
4 2Z49 AMG 0.01127 0.4328 1.56658
5 5GZ9 ANP 0.000003681 0.51377 1.63934
6 3WVR AMP 0.0006029 0.46985 1.82768
7 2VQD AP2 0.0005807 0.45224 1.82768
8 2IO8 ADP 0.0006431 0.43873 1.82768
9 3KA2 2NC 0.01309 0.40712 1.97044
10 4GYI ADP 0.000008027 0.56554 2.08877
11 3K5I ADP 0.001339 0.43654 2.08877
12 3VSV XYS 0.01402 0.42112 2.08877
13 1U1J MET 0.01624 0.41603 2.08877
14 1PK8 ATP 0.0009329 0.4287 2.1327
15 4LH7 1X8 0.0002831 0.51661 2.16718
16 4CC6 L5Y 0.01021 0.42415 2.20126
17 5C1P ADP 0.00075 0.4705 2.28758
18 2YW2 ATP 0.0004061 0.45896 2.34987
19 4UWH JXM 0.009178 0.41404 2.34987
20 5BRP PNG 0.03215 0.40496 2.34987
21 3DNT ATP 0.004607 0.40383 2.34987
22 4FE2 AIR 0.003222 0.44461 2.35294
23 4FE2 ADP 0.003866 0.43611 2.35294
24 5O0X FAD 0.01989 0.40539 2.4055
25 5V1B 8UY 0.005839 0.44147 2.5
26 4R78 AMP 0.0003341 0.49948 2.589
27 4RDL FUC GAL NDG FUC 0.01041 0.43127 2.5974
28 5VZ0 ADP 0.0001807 0.4223 2.61097
29 1F52 ADP 0.01417 0.40879 2.61097
30 1OBD ATP 0.00006488 0.43109 2.61438
31 1I06 TZL 0.009012 0.43164 2.77778
32 3VPC ADP 0.0002015 0.46766 2.83688
33 3VPB ADP 0.0001875 0.45659 2.83688
34 5GZK BGC 0.03304 0.40554 2.87206
35 4OCJ NDG 0.001635 0.43438 2.90237
36 4XDA RIB 0.02354 0.40172 2.91262
37 5IQD RIO 0.00002751 0.50898 2.95082
38 5IQD GNP 0.00002536 0.50898 2.95082
39 4B1L FRU 0.01491 0.42204 3.0303
40 2PYW ADP 0.00001177 0.48439 3.13316
41 4R8L ASP 0.01265 0.4194 3.13316
42 5TT6 ATP 0.002848 0.41888 3.13316
43 3X01 AMP 0.00003047 0.564 3.30789
44 3T4L ZEA 0.008849 0.40755 3.33333
45 1Q8A HCS 0.02367 0.40971 3.39426
46 2Q7D ANP 0.002897 0.40405 3.46821
47 3LQV ADE 0.007833 0.44849 3.47826
48 1TQP ATP 0.000003458 0.53126 3.5461
49 4LRJ ANP 0.0000009491 0.50193 3.5503
50 2IF8 ADP 0.0004179 0.50107 3.58127
51 5FCF GLY GLY GLY 0.009279 0.41924 3.65535
52 5N49 8LW 0.01201 0.42511 3.7037
53 1MJT ITU 0.0149 0.42014 3.7464
54 5T96 79J 0.007534 0.43572 3.80117
55 4XYM A12 0.002076 0.43207 3.87931
56 1I7L ATP 0.0002894 0.45287 3.8835
57 5MW8 ATP 0.000005966 0.50659 3.91645
58 4OCV ANP 0.0001709 0.47995 3.95778
59 3ORQ ADP 0.002146 0.42768 3.97878
60 3I0O ADP 0.0001483 0.51069 4.12979
61 2BKK ADP 0.004716 0.43194 4.14201
62 5LXT ACP 0.002518 0.41778 4.1958
63 4OUC 5ID 0.000003424 0.57569 4.20168
64 1YNS HPO 0.03712 0.40209 4.21456
65 5W2I I3P 0.001553 0.42311 4.28016
66 5W2I ADP 0.001553 0.42311 4.28016
67 4CYI ATP 0.000006039 0.49352 4.43864
68 4NS0 PIO 0.03984 0.40885 4.51128
69 2YRX AMP 0.0007169 0.49085 4.69974
70 2CFM AMP 0.0004899 0.48506 4.69974
71 2ZHL NAG GAL GAL NAG 0.02104 0.40044 4.72973
72 4CLI 5P8 0.00000004016 0.63711 4.89297
73 3TDV GDP 0.000006049 0.55035 4.90196
74 4OAV ACP 0.000001179 0.58974 4.96084
75 3AB4 THR 0.02456 0.40081 4.96084
76 4QM9 CYS 0.02044 0.41376 5.20231
77 4ZS4 ATP 0.000005651 0.54532 5.21173
78 4AZT LY2 0.000335 0.49322 5.22193
79 2OVW CBI 0.03581 0.40018 5.22193
80 3AKK ADP 0.0005917 0.45614 5.23077
81 4P5Z Q7M 0.000005083 0.44977 5.26316
82 3KRL KRL 0.00001574 0.5146 5.37313
83 3P2H MTA 0.01784 0.41673 5.47264
84 1HFE CYS 0.02026 0.41881 5.48303
85 5L6G XYP 0.01869 0.41439 5.48303
86 3E7S AT2 0.03064 0.40622 5.48303
87 3VHE 42Q 0.000001907 0.50331 5.57103
88 4ASE AV9 0.00001597 0.48329 5.66572
89 3HAV ATP 0.0002331 0.5171 5.68562
90 5N1X 8HH 0.001612 0.44276 5.78512
91 3PDT ADP 0.00001697 0.54293 5.81818
92 4E93 GUI 0.000002815 0.48505 5.83554
93 5AVF TAU 0.01406 0.41706 5.83658
94 5NKB 8ZT 0.000002703 0.44415 5.88235
95 4H4D 10E 0.013 0.41062 5.88235
96 5C4L 4XR 0.0004535 0.4495 5.919
97 5C4L SIS 0.002851 0.41672 5.919
98 3Q60 ATP 0.0000008032 0.59742 5.92992
99 3GNI ATP 0.000006185 0.53755 6.00522
100 5DMZ ADP 0.000004221 0.5574 6.0274
101 1VJY 460 0.000009385 0.46821 6.27063
102 4OH4 ANP 0.0000004171 0.60272 6.30631
103 5LPZ ADP 0.0000004275 0.60224 6.3253
104 4AG8 AXI 0.000008451 0.45308 6.32911
105 4A91 GLU 0.01387 0.41365 6.37584
106 4U98 ACP 0.0004305 0.47166 6.52742
107 4PU5 ANP 0.002946 0.41494 6.52742
108 4N70 2HX 0.000001318 0.57785 6.70732
109 3RI1 3RH 0.000001249 0.546 6.70927
110 1OPB RET 0.01501 0.40044 6.71642
111 3KMT SAH 0.01402 0.40532 6.72269
112 3UIM ANP 0.000002556 0.56722 6.74847
113 5I35 ANP 0.000006065 0.55696 6.78851
114 3UDZ ADP 0.00001162 0.47686 6.78851
115 5CKW ANP 0.00003922 0.42809 6.78851
116 5HES 032 0.00003015 0.47317 6.84039
117 4Q5H ANP 0.000005757 0.55132 6.89655
118 1EHI ADP 0.001262 0.44162 6.89655
119 3RE4 TO1 0.00001669 0.55757 6.97674
120 3CY2 MB9 0.000001712 0.54945 7.00637
121 5LPB ADP 0.0000003709 0.63924 7.09459
122 3TII ANP 0.001461 0.4616 7.10526
123 4CQE CQE 0.00006306 0.48904 7.19424
124 2OO8 RAJ 0.001173 0.43523 7.25552
125 3NZ1 3NY 0.02823 0.41079 7.27969
126 4DFU QUE 0.004019 0.44992 7.31071
127 3GQI ACP 0.000000175 0.61973 7.36196
128 2VPQ ANP 0.0002615 0.44296 7.5718
129 4BHL ARG 0.004421 0.4404 7.58427
130 1OIJ AKG 0.01889 0.41651 7.6412
131 5UR1 YY9 0.00004999 0.50345 7.71704
132 3TKI S25 0.0000004553 0.6032 7.73994
133 3SRV S19 0.0000000597 0.54126 7.94224
134 4IX4 ADP 0.0002026 0.4377 8
135 4WW7 AMP 0.00001126 0.49002 8.04598
136 4F4P 0SB 0.0000016 0.58513 8.05861
137 2QX0 PH2 0.004646 0.44205 8.1761
138 4J25 OGA 0.03894 0.40036 8.29694
139 5VC5 96M 0.000001899 0.54089 8.3045
140 2PUL ACP 0.000003181 0.56988 8.35509
141 1OGX EQU 0.01264 0.40745 8.39695
142 4EUU BX7 0.00001046 0.49937 8.46395
143 4O1P ANP 0.0000001178 0.53667 8.61619
144 1CBK ROI 0.00352 0.45576 8.75
145 5MRH Q9Z 0.002948 0.45156 8.87729
146 4K33 ACP 0.000000129 0.54794 8.92308
147 1XJD STU 0.000002013 0.56511 8.98551
148 1W2D ADP 0.0005781 0.4815 9.0566
149 3AQV TAK 0.0002673 0.41951 9.05797
150 5C03 AGS 0.00002111 0.52588 9.06433
151 3KMW ATP 0.00009127 0.5027 9.30233
152 5JKG 6LF 0.00008815 0.48771 9.32476
153 4YZC STU 0.000000754 0.57293 9.39948
154 5M06 ADP 0.000001291 0.59565 9.42029
155 4CS9 AMP 0.003618 0.43998 9.52381
156 5TO8 7FM 0.000005995 0.44188 9.57447
157 3VOT ADP 0.0006709 0.47831 9.66057
158 4WOV 3SM 0.00001966 0.54678 9.77918
159 1TZD ADP 0.002754 0.45335 9.81818
160 2X1L MET 0.01829 0.41258 9.92366
161 3H9R TAK 0.000002948 0.60354 10.303
162 1T36 ADP 0.00385 0.40713 10.4712
163 5MJA 7O3 0.0000006 0.49692 10.4918
164 2GQS ADP 0.001144 0.4521 10.5485
165 2GQS C2R 0.003668 0.43286 10.5485
166 2Y6O 1N1 0.000001325 0.56015 10.6529
167 1OPK P16 0.0001702 0.43015 10.705
168 3ETH ATP 0.001883 0.40599 10.705
169 1M0W ANP 0.0004669 0.40501 10.705
170 3QRC SCR 0.02379 0.4052 10.828
171 1ZP9 ATP 0.000002888 0.57917 10.8527
172 1ZTH ADP 0.000002815 0.45638 10.8527
173 5JFS 6K0 0.00001443 0.52368 11.039
174 2X2M X2M 0.000002233 0.51619 11.1465
175 4ZGP ADP 0.009971 0.40868 11.2628
176 4FL3 ANP 0.0000003297 0.58575 11.3386
177 3PVW QRX 0.000001397 0.53355 11.4883
178 5UKL SIX 0.00001723 0.50216 11.4883
179 4I94 ANP 0.000003425 0.47983 11.6667
180 3FHR P4O 0.00005926 0.50026 11.9048
181 2XVD AS6 0.000001736 0.5131 11.9205
182 4RW3 DKA 0.01534 0.43406 11.9205
183 2A19 ANP 0.0000002837 0.64499 11.9718
184 4XV1 904 0.000005838 0.53067 11.9863
185 4A4X JUP 0.0000009282 0.53971 12.5448
186 2QLU ADE 0.000008274 0.588 12.7389
187 3M2W L8I 0.000000676 0.4873 13.0435
188 4L9I 8PR 0.000001187 0.5896 13.0952
189 5USZ SKE 0.000007263 0.49822 13.4948
190 4XMF HSM 0.0006122 0.47878 14.1304
191 5KO1 6UY 0.00000008327 0.64278 14.1343
192 3MMH SME 0.02215 0.40305 14.9701
193 4XLI 1N1 0.000001322 0.58746 15.2985
194 4IDT T28 0.00002138 0.53175 15.7303
195 5T8O 76Z 0.000002552 0.55418 15.7593
196 4WNK 453 0.000002092 0.50422 16.188
197 5CEO 50D 0.0000006266 0.51287 16.3333
198 3VRY B43 0.00001015 0.50727 16.4491
199 2R5T ANP 0.00000285 0.54605 16.8901
200 2HY0 306 0.000002038 0.59426 17.2324
201 3E8N ATP 0.000001987 0.43508 17.3021
202 3E8N VRA 0.000001987 0.43508 17.3021
203 3ALN ANP 0.000001176 0.56873 17.4312
204 3TXO 07U 0.00000003746 0.53422 17.5637
205 5DBX ANP 0.0000001388 0.50841 17.6829
206 4XH0 ADP 0.000000269 0.67395 17.7546
207 1Y57 MPZ 0.0000007632 0.56403 17.7546
208 2H8H H8H 0.000004981 0.55416 17.7546
209 4Y85 499 0.001096 0.45295 17.7711
210 4U0I 0LI 0.0003508 0.41799 18.0952
211 3V8S 0HD 0.0000001807 0.62727 18.2768
212 4G31 0WH 0.00006598 0.43049 18.3946
213 1WAP TRP 0.01159 0.40566 18.6667
214 3MVH WFE 0.0000001307 0.59254 19.0058
215 1JPA ANP 0.00000254 0.58358 19.2308
216 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.0000006918 0.40388 19.2982
217 2JDR L20 0.0000006918 0.40388 19.2982
218 4OTH DRN 0.0000002793 0.5888 19.3548
219 5IH9 6BF 0.000005168 0.53628 19.403
220 4ZSD 7I6 0.007416 0.41463 19.5122
221 1U5R ATP 0.0000001566 0.6219 19.5402
222 3LXK MI1 0.000007622 0.49761 19.5719
223 2YAB AMP 0.000001055 0.57749 19.6676
224 4G17 0VN 0.000007458 0.46301 19.697
225 3PLS ANP 0.0000000767 0.64442 19.7987
226 4BTK DTQ 0.00001122 0.46947 19.8813
227 5U6C 7YS 0.000003028 0.54493 20
228 4BFM ANP 0.0000002666 0.5966 20.0599
229 2PZI AXX 0.00000441 0.57809 20.1044
230 5UIU 8CG 0.000001907 0.545 20.1238
231 2CSN CKI 0.001177 0.45722 20.5387
232 2BOS GLA GAL 0.01725 0.4089 20.5882
233 5K2M ADP 0.0009089 0.4258 20.7547
234 4BKJ STI 0.0005294 0.43855 20.9524
235 4YMJ 4EJ 0.00000008034 0.70193 21.0526
236 3HMO STU 0.0000001802 0.62733 21.0526
237 4U44 3D9 0.00001682 0.46708 21.3855
238 3PP0 03Q 0.00003752 0.4773 21.5976
239 4E1Z 0MX 0.00000654 0.52525 21.6495
240 4NFN 2KC 0.00001167 0.54386 21.6828
241 4M69 ANP 0.0000174 0.51812 21.7252
242 3NW7 LGV 0.00001298 0.53236 21.8241
243 4L3L 5FI 0.00000007734 0.60184 22.0395
244 5N87 N66 0.000003423 0.4664 22.0447
245 5W4W 9WG 0.000001433 0.50063 22.0544
246 4KBA 1QM 0.000008792 0.49457 22.0544
247 4Y0X ADP 0.000001006 0.49138 22.1333
248 5HVJ ANP 0.0000004732 0.66117 22.2222
249 4YZN 4K5 0.000000625 0.56763 22.2997
250 5AX9 4KT 0.00002785 0.52045 22.4026
251 1K3A ACP 0.00000005651 0.66936 22.408
252 4C2V YJA 0.000004623 0.49243 22.4561
253 5HCY 60D 0.00000005338 0.47834 22.6586
254 5HX8 66P 0.000007085 0.5056 22.8477
255 4C2W ANP 0.00000003481 0.52243 22.9391
256 4Y8D 49J 0.000000215 0.6157 22.9412
257 4EWH T77 0.000001732 0.52129 23.2727
258 2HK5 1BM 0.000003252 0.5018 23.3333
259 4USF 6UI 0.0001299 0.45848 23.3553
260 3G5D 1N1 0.000001651 0.5811 23.4266
261 5EYK 5U5 0.000002195 0.51763 23.5507
262 3SXS PP2 0.0000006694 0.57931 23.8806
263 1U59 STU 0.000000314 0.60828 24.0418
264 3EKK GS2 0.000001198 0.47318 24.1042
265 3BU5 ATP 0.00000002917 0.55871 24.183
266 2OFV 242 0.00003163 0.43533 24.1877
267 3LXN MI1 0.0000006576 0.57964 24.2138
268 5VCV 1N1 0.0000001571 0.586 24.282
269 3C1X CKK 0.00008576 0.48338 24.282
270 4D2S DYK 0.000005099 0.57505 24.2958
271 2ZV2 609 0.00000004198 0.68599 24.8322
272 4GJ3 0XP 0.000008522 0.47507 25.1656
273 4WB7 ATP 0.000008903 0.44875 25.3264
274 5A6N U7E 0.0000002098 0.53727 25.4417
275 5TA6 79D 0.000005577 0.50219 26.5363
276 4JR7 GNP 0.0000002441 0.61321 26.738
277 5FBN 5WF 0.00001573 0.51451 26.9373
278 5H2U 1N1 0.000007093 0.54723 26.9663
279 1BYG STU 0.0000004743 0.61615 26.9784
280 5DA3 58V 0.0000001869 0.65395 27.1698
281 4CSV STI 0.00009631 0.47671 27.2727
282 2QCS ANP 0.0000004653 0.56325 27.7143
283 3FHI ANP 0.0000005112 0.56161 27.7143
284 3IDB ANP 0.00000282 0.54044 27.7143
285 1RE8 BD2 0.000009475 0.53825 27.7143
286 4WB6 ATP 0.0000009337 0.55109 28
287 4KS7 X4Z 0.000000585 0.56883 28.7671
288 2GU8 796 0.000002012 0.40393 28.7834
289 5EOB 5QQ 0.00001358 0.53975 28.8401
290 4Y93 746 0.00002044 0.4951 29.2428
291 2JLD AG1 0.0000007851 0.49826 29.5039
292 4DC2 ADE 0.00000007178 0.45416 29.5039
293 4NM5 ADP 0.0000001043 0.59995 29.9735
294 3KN5 ANP 0.000002439 0.47353 30.1538
295 1PHK ATP 0.00000006306 0.55739 30.2013
296 5LVP ATP 0.00000001539 0.54423 30.2251
297 5LI1 ANP 0.0000001747 0.55733 30.226
298 5DH3 5BS 0.00001083 0.52703 30.4762
299 2Z7R STU 0.0000006269 0.57392 30.5296
300 4NW6 2NS 0.000004286 0.47812 30.9598
301 4BHN BH9 0.00002351 0.51247 31.4371
302 5LI9 ACP 0.0000000742 0.62838 32
303 5H4I 7HQ 0.02591 0.40316 32.0755
304 3F7Z 34O 0.000002787 0.4912 32.2857
305 2WQN ADP 0.00000007464 0.66353 32.9032
306 4X7Q 3YR 0.000001282 0.58074 33.0128
307 4QXB OGA 0.02777 0.40194 33.3333
308 4QMN DB8 0.0000001434 0.50822 33.871
309 3KRR DQX 0.000003263 0.57557 33.8983
310 4AT3 LTI 0.00006204 0.45055 34.4482
311 3DLS ADP 0.000008044 0.46191 34.6269
312 3ORK AGS 0.00000112 0.54556 34.7267
313 3SLS ANP 0.0000005877 0.57511 34.8684
314 3GGF GVD 0.000003539 0.57501 34.8837
315 3IGO ANP 0.0000009997 0.56533 35.5091
316 2RIO ADP 0.0000002339 0.52407 35.7702
317 2B9I ADP 0.0000003909 0.60399 36.5439
318 3HZT J60 0.000000561 0.63036 36.5535
319 4JDI ANP 0.0000001221 0.61126 36.7052
320 5DRB 5FJ 0.000004867 0.42098 37.1134
321 2BPM 529 0.0000005448 0.43629 37.5405
322 4CFU 2WC 0.000001126 0.59845 37.9538
323 4I6H 1C8 0.0000246 0.52289 37.987
324 5JZJ AN2 0.0000001171 0.63596 38.0471
325 4BCM T7Z 0.000002124 0.62033 38.206
326 4BCQ TJF 0.00001452 0.44053 38.206
327 5L8L ADP 0.0000002198 0.65047 38.2456
328 5G1X ADP 0.000001867 0.58054 38.2456
329 4BCN T9N 0.000007691 0.56644 38.3333
330 2V7O DRN 0.00000003436 0.50659 38.3929
331 4QTB 38Z 0.0000004561 0.56819 38.4211
332 3C0G 3AM 0.0000002331 0.63968 38.4615
333 5LXM ADP 0.000001944 0.57974 38.5159
334 5LMK 6ZK 0.00005203 0.43595 38.7205
335 5UOX 8GY 0.00002567 0.50559 38.7454
336 3SXF BK5 0.000003084 0.46912 38.9034
337 4CRL C1I 0.000003981 0.47157 38.9163
338 2XMY CDK 0.00008512 0.51307 38.9262
339 4F9C 0SX 0.0000001452 0.52546 39.0582
340 4H3P ANP 0.00000008448 0.63399 39.2265
341 2WEL K88 0.0000001244 0.46959 39.7554
342 4H3Q ANP 0.000001442 0.52899 39.779
343 1CM8 ANP 0.00009024 0.43327 39.782
344 5EKO N17 0.00004815 0.4687 39.8922
345 2PVF ACP 0.0000000134 0.67933 40
346 5EW9 5VC 0.00001089 0.57592 40.2214
347 3ZRM ZRM 0.00000004013 0.55496 40.625
348 3E5A VX6 0.000003805 0.52432 40.6716
349 2XK9 XK9 0.004093 0.44402 40.6832
350 3TTI KBI 0.00000213 0.51887 40.7311
351 4WNP 3RJ 0.000001795 0.59691 41.115
352 5AWM ANP 0.000004886 0.58392 41.2533
353 3E7O 35F 0.00001993 0.45486 41.3889
354 2PVN P63 0.0000002592 0.54372 41.4773
355 1OUK 084 0.000008535 0.58091 41.8033
356 4LOO SB4 0.0001723 0.42708 42.1053
357 2VZ6 FEF 0.000001468 0.60113 42.1725
358 3GC8 B45 0.00006243 0.48923 42.4324
359 5BYZ 4WE 0.00004354 0.45218 42.5287
360 5EFQ ADP 0.0000001677 0.5331 42.6513
361 4NST ADP 0.0000006561 0.59385 42.735
362 2X4Z X4Z 0.000001239 0.48686 42.9054
363 3PTG 932 0.000006778 0.44303 42.9752
364 2VN9 GVD 0.000000009334 0.52576 43.1894
365 4UX9 ANP 0.0000004582 0.58643 43.4066
366 3OFM 4B0 0.00000003813 0.52685 43.4286
367 4FG8 ATP 0.0000001042 0.55966 44.7619
368 2YAK OSV 0.00000001056 0.58358 46.6667
369 5LXC 7AA 0.000000002501 0.57405 46.7363
370 2WEI VGG 0.0000004721 0.61624 47.0383
371 5DEY 59T 0.00000694 0.40237 47.138
372 4IJP 1EH 0.0000002515 0.54417 47.2067
373 3DAK ANP 0.00000005208 0.66135 47.2414
374 3PE2 E1B 0.0000009247 0.58175 47.4777
375 2WU6 DKI 0.00000000189 0.67234 48.0315
376 3GC0 AMP 0.00001374 0.55428 48.3283
377 4YLL 4E3 0.000000005695 0.62016 48.4765
378 5HQ0 LZ9 0.0000005371 0.58345 49.0066
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