-->
Receptor
PDB id Resolution Class Description Source Keywords
1OFS 1.8 Å NON-ENZYME: BINDING PEA LECTIN-SUCROSE COMPLEX PISUM SATIVUM LECTIN PLANT LECTIN CARBOHYDRATE BINDING PROTEIN CALCIUM GLYCOPROTEIN
Ref.: PEA LECTIN-SUCROSE COMPLEX TO BE PUBLISHED
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:1183;
C:1183;
Part of Protein;
Part of Protein;
none;
none;
submit data
40.078 Ca [Ca+2...
MN A:1182;
C:1182;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
SUC A:1184;
C:1184;
Valid;
Valid;
none;
none;
submit data
342.296 C12 H22 O11 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1OFS 1.8 Å NON-ENZYME: BINDING PEA LECTIN-SUCROSE COMPLEX PISUM SATIVUM LECTIN PLANT LECTIN CARBOHYDRATE BINDING PROTEIN CALCIUM GLYCOPROTEIN
Ref.: PEA LECTIN-SUCROSE COMPLEX TO BE PUBLISHED
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1BQP - MAN C6 H12 O6 C([C@@H]1[....
2 1OFS - SUC C12 H22 O11 C([C@@H]1[....
3 1HKD - GYP C7 H14 O6 CO[C@@H]1[....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1LES - GLC FRU n/a n/a
2 1BQP - MAN C6 H12 O6 C([C@@H]1[....
3 1OFS - SUC C12 H22 O11 C([C@@H]1[....
4 1HKD - GYP C7 H14 O6 CO[C@@H]1[....
5 1LOA - GYP C7 H14 O6 CO[C@@H]1[....
6 1LOC - MDP DAL ZGL n/a n/a
7 1LOB - MMA C7 H14 O6 CO[C@@H]1[....
8 1LOG - MAN BMA NAG n/a n/a
9 1LOD - MUR C9 H17 N O7 C[C@H](C(=....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1LES - GLC FRU n/a n/a
2 1BQP - MAN C6 H12 O6 C([C@@H]1[....
3 1OFS - SUC C12 H22 O11 C([C@@H]1[....
4 1HKD - GYP C7 H14 O6 CO[C@@H]1[....
5 1LOA - GYP C7 H14 O6 CO[C@@H]1[....
6 1LOC - MDP DAL ZGL n/a n/a
7 1LOB - MMA C7 H14 O6 CO[C@@H]1[....
8 1LOG - MAN BMA NAG n/a n/a
9 1LOD - MUR C9 H17 N O7 C[C@H](C(=....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SUC; Similar ligands found: 16
No: Ligand ECFP6 Tc MDL keys Tc
1 SUC 1 1
2 SWE 1 1
3 RAF 0.736842 0.972973
4 STW 0.724138 0.972973
5 SUP 0.701754 0.8
6 DQR 0.666667 0.972973
7 NYT 0.612903 0.972973
8 FNY 0.612903 0.972973
9 20S 0.534247 0.8
10 SUC GLA 0.5 0.921053
11 AGR 0.467532 0.782609
12 TRE 0.42 0.864865
13 AMG 0.411765 0.789474
14 MMA 0.411765 0.789474
15 GYP 0.411765 0.789474
16 MBG 0.411765 0.789474
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1OFS; Ligand: SUC; Similar sites found with APoc: 191
This union binding pocket(no: 1) in the query (biounit: 1ofs.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 2NU5 NAG None
2 2GUC MAN None
3 2GUD MAN None
4 2HYR BGC GLC None
5 2GUD BMA None
6 2HYQ MAN MAN None
7 2NUO BGC None
8 2GUE NAG None
9 3LL2 MAN MAN MAN MAN MAN MAN MAN MAN None
10 2FLI DX5 None
11 1GUA GNP None
12 5KVA SAM 1.06952
13 2JG1 ANP 1.60428
14 4POO SAM 2.13904
15 5DXA SFG 2.13904
16 5DX1 SFG 2.13904
17 2CM4 RCL 2.66667
18 5AR0 GB8 2.6738
19 4X6I 3Y1 2.6738
20 2YVK MRU 2.6738
21 2ZC0 PMP 3.20856
22 3G5S FAD 3.20856
23 3LAD FAD 3.20856
24 3X1Z GNP 3.59281
25 4L2H AR6 AR6 3.74332
26 4HA6 FAD 3.74332
27 6GAS FAD 3.74332
28 3RIY NAD 3.74332
29 5NII FAD 3.74332
30 5MQ5 ASP 3.74332
31 1Q5H DUD 4.08163
32 5XFH NAG MAN BMA MAN NAG GAL 4.13793
33 1X9I G6Q 4.16667
34 6F3M NAD 4.27807
35 1ZK4 NAP 4.27807
36 3JZ4 NAP 4.27807
37 2WLT ASP 4.27807
38 4HDQ GNP 4.27807
39 1MV8 NAD 4.27807
40 4UP3 NDP 4.81283
41 1IIM TTP 4.81283
42 3BF1 ADP 4.81283
43 2J9C ATP 5.04202
44 3VGL ANP 5.29595
45 5KMS FAD 5.34759
46 5VN0 FAD 5.34759
47 3BY8 MLT 5.6338
48 1Q1R FAD 5.88235
49 2JAH NDP 5.88235
50 5DN9 NAD 5.88235
51 5TQZ GLC 6
52 5YRG BGC GLC 6.25
53 5YRF GLC GLC 6.25
54 3R51 MMA 6.25
55 4YUW S4M 6.25
56 1D4D FAD 6.25
57 2Q2V NAD 6.25
58 2BTO GTP 6.25
59 3F8D FAD 6.25
60 3HDY GDU 6.25
61 3HDY FAD 6.25
62 1C4U IH1 6.25
63 1RP0 AHZ 6.25
64 5FJN FAD 6.25
65 5FJN BE2 6.25
66 1COY AND 6.41711
67 1COY FAD 6.41711
68 1WUR 8DG 6.41711
69 1JQ3 AAT 6.95187
70 3GD4 NAD 6.95187
71 5WDR GNP 7.01754
72 5OC1 FAD 7.48663
73 3ICC NAP 7.48663
74 1KEV NDP 8.02139
75 1L3I SAH 8.02139
76 5YSS NAD 8.33333
77 2CUN 3PG 8.33333
78 4MO2 FAD 8.33333
79 4MO2 FDA 8.33333
80 1FL2 FAD 8.33333
81 1S7G NAD 8.33333
82 2JK0 ASP 8.33333
83 1N9G NAP 8.33333
84 5CB3 APR 8.33333
85 5F52 ASP 8.55615
86 1LDN NAD 8.55615
87 5X20 NAD 8.55615
88 4M52 FAD 9.09091
89 2A8X FAD 9.09091
90 1IDA 0PO 9.09091
91 1WPY BTN 9.09091
92 3VY6 BGC BGC 9.21986
93 6D5G GNP 9.58084
94 6D55 GNP 9.58084
95 4TM3 FAD 9.62567
96 2XAU ADP 9.62567
97 4QTB 38Z 9.62567
98 1NVV GNP 9.63855
99 1I8T FAD 10.1604
100 1TDF FAD 10.1604
101 4ZGS NAD 10.4167
102 6F7L FAD 10.4167
103 3Q9T FAY 10.4167
104 1BXG HCI 10.4167
105 5BSH PRO 10.4167
106 4JBI NDP 10.4167
107 1C1D PHE 10.4167
108 1A8R GTP 10.4167
109 5GM9 CBK 10.6952
110 5GUD NDP 10.6952
111 1GQ2 NAP 10.6952
112 3RYC GDP 11.2299
113 5ITZ GTP 11.2299
114 3RYC GTP 11.2299
115 5EIB GTP 11.2299
116 5LXT GTP 11.2299
117 4RPL 3UC 11.2299
118 4RPL FAD 11.2299
119 4LNU GTP 11.2299
120 5EYP GTP 11.2299
121 5D85 P1T 11.2299
122 3CR3 ADP 11.5702
123 4PLT OXM 12.2995
124 4PLT NAI 12.2995
125 1P9B HDA 12.2995
126 1P9B IMO 12.2995
127 4I4Z 2NE 12.5
128 3VZS NAP 12.5
129 4MOP 2H5 12.5
130 1JXZ BCA 12.5
131 4L2I FAD 12.5
132 1NZY BCA 12.5
133 5YLT SFG 12.5
134 5YLT C7N 12.5
135 3WGT FAD 12.5
136 5UY8 AMZ 12.5
137 2O2C G6Q 12.5
138 3KB6 NAD 12.5
139 4DXD 9PC 12.5
140 1V59 FAD 13.369
141 1SZD APR 14.4385
142 2OD9 A1R NCA 14.4385
143 1ELI PYC 14.5833
144 2R4J 13P 14.5833
145 2R4J FAD 14.5833
146 1X7D NAD 14.5833
147 3OA2 NAD 14.5833
148 1J49 NAD 14.5833
149 2X7J TPP 14.5833
150 1IXE COA 14.5833
151 2V6G NAP 14.5833
152 1OBB NAD 14.5833
153 1I36 NAP 14.9733
154 3CB2 GDP 14.9733
155 1LBZ FBP 14.9733
156 4J4H NAI 15.508
157 4J4H 1J1 15.508
158 4XOI GTP 15.508
159 4JK3 NAD 15.508
160 5YRI GLC GLC 16.6667
161 5YRM BGC GLC 16.6667
162 5YRJ BGC GLC 16.6667
163 5YRL GLC GLC 16.6667
164 3ORF NAD 16.6667
165 1O94 ADP 16.6667
166 1LYX PGA 16.6667
167 6GNC FAD 16.6667
168 1CER NAD 18.1818
169 2GAG NAD 18.75
170 2UYT LRH 18.75
171 2UYT ADP 18.75
172 2PT9 S4M 18.75
173 2I7C AAT 18.75
174 4MIG G3F 18.75
175 4FG8 ATP 18.75
176 4Q4K FMN 18.75
177 1GZ4 ATP 18.75
178 2DUR MAN MAN 19.7861
179 4ZNO SUC 20.8333
180 5JWC FAD 20.8333
181 4FZV SAM 20.8333
182 1B8O IMH 20.8333
183 1M7Y PPG 20.8333
184 1NJJ ORX 20.8333
185 2Y4O DLL 22.9167
186 2IVF MGD 25
187 2ZXI FAD 25
188 2YVJ NAI 25
189 1YNH SUO 27.0833
190 6GNA FAD 31.25
191 4K81 GTP 35.4167
Pocket No.: 2; Query (leader) PDB : 1OFS; Ligand: SUC; Similar sites found with APoc: 76
This union binding pocket(no: 2) in the query (biounit: 1ofs.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 3HGM ATP None
2 3ZBQ GDP 3.20856
3 2JAP NDP 4.27807
4 1YJQ NAP 4.27807
5 4UP3 FAD 4.81283
6 2FWP ICR 4.91803
7 6BQ6 TER 5.34759
8 4GLL NAD 6.25
9 2RGO FAD 6.41711
10 6CI9 NAP 6.41711
11 6FA4 GNP 6.93642
12 2YG3 FAD 6.95187
13 1PJS NAD 6.95187
14 4GKV NAD 8.02139
15 1QF5 RPL 8.33333
16 1QF5 GDP 8.33333
17 5I34 IMP 8.33333
18 3C6K SPD 8.33333
19 3C6K MTA 8.33333
20 2VUT NAD 8.33333
21 4PNI KQQ 8.33333
22 2QWO ADP 9.09091
23 3LDQ 3P1 9.09091
24 3FPZ AHZ 9.62567
25 1RQ2 CIT 9.62567
26 5OVL NAP 9.62567
27 3GF4 UPG 10.1604
28 3GF4 FAD 10.1604
29 1TDF NAP 10.1604
30 4HA9 NDP 10.1604
31 1C1X NAD 10.4167
32 3UCL CYH 10.4167
33 3UCL FAD 10.4167
34 3UCL NAP 10.4167
35 4RF2 NAP 10.4167
36 1BXG NAD 10.4167
37 5G3U FDA 10.4167
38 5G3U ITW 10.4167
39 3QJ4 FAD 10.4167
40 3AFN NAP 10.4167
41 5ITZ GDP 11.2299
42 5EYP GDP 11.2299
43 5LXT 7AK 11.2299
44 4LNU GDP 11.2299
45 5FPE 3TR 11.2299
46 3ENG CBI 11.7647
47 4XSU GLC 12.5
48 3IES M24 12.5
49 5DK4 ATP 12.5
50 5DK4 5BX 12.5
51 1DJN ADP 12.5
52 5ZYN FAD 12.8342
53 1KNR FAD 12.8342
54 1X7D ORN 14.5833
55 3ABI NAD 14.5833
56 4S3F 43W 14.5833
57 1TZJ A3B 14.5833
58 4C3Y FAD 14.5833
59 2Z6J FMN 14.5833
60 2V7B BEZ 14.5833
61 6F97 FAD 16.6667
62 1KOJ PAN 16.6667
63 1I2L DCS 16.6667
64 2PT9 2MH 18.75
65 5C5H 4YB 18.75
66 3GFS FMN 18.75
67 4YSX FAD 20.8333
68 2CUL FAD 20.8333
69 3AD8 NAD 25
70 4EMJ FAD 25
71 1PS9 NAP 25
72 2F5Z FAD 27.0833
73 3RNM FAD 27.0833
74 5FFF NAP 29.1667
75 3ICS FAD 37.5
76 3ICR FAD 37.5
APoc FAQ
Feedback