Receptor
PDB id Resolution Class Description Source Keywords
1LOG 2.1 Å NON-ENZYME: BINDING X-RAY STRUCTURE OF A (ALPHA-MAN(1-3)BETA-MAN(1-4)GLCNAC)-LEC COMPLEX AT 2.1 ANGSTROMS RESOLUTION LATHYRUS OCHRUS LECTIN
Ref.: X-RAY STRUCTURE OF A (ALPHA-MAN(1-3)BETA-MAN(1-4)GLCNAC)-LECTIN COMPLEX RESOLUTION. THE ROLE OF WATER IN SUGAR-LECTIN INTER J.BIOL.CHEM. V. 265 18161 1990
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:561;
C:571;
Part of Protein;
Part of Protein;
none;
none;
submit data
40.078 Ca [Ca+2...
MAN BMA NAG A:591;
C:581;
Valid;
Valid;
none;
none;
submit data
545.491 n/a O=C(N...
MN A:562;
C:572;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1LOB 2 Å NON-ENZYME: BINDING THREE-DIMENSIONAL STRUCTURES OF COMPLEXES OF LATHYRUS OCHRUS I WITH GLUCOSE AND MANNOSE: FINE SPECIFICITY OF THE MONOSACB INDING SITE LATHYRUS OCHRUS LECTIN
Ref.: THREE-DIMENSIONAL STRUCTURES OF COMPLEXES OF LATHYR ISOLECTIN I WITH GLUCOSE AND MANNOSE: FINE SPECIFIC THE MONOSACCHARIDE-BINDING SITE. PROTEINS V. 8 365 1990
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 1LOA - GYP C7 H14 O6 CO[C@@H]1[....
2 1LOC - MDP DAL ZGL n/a n/a
3 1LOB - MMA C7 H14 O6 CO[C@@H]1[....
4 1LOG - MAN BMA NAG n/a n/a
5 1LOD - MUR C9 H17 N O7 C[C@H](C(=....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1LES - GLC FRU n/a n/a
2 1BQP - MAN C6 H12 O6 C([C@@H]1[....
3 1OFS - SUC C12 H22 O11 C([C@@H]1[....
4 1HKD - GYP C7 H14 O6 CO[C@@H]1[....
5 1LOA - GYP C7 H14 O6 CO[C@@H]1[....
6 1LOC - MDP DAL ZGL n/a n/a
7 1LOB - MMA C7 H14 O6 CO[C@@H]1[....
8 1LOG - MAN BMA NAG n/a n/a
9 1LOD - MUR C9 H17 N O7 C[C@H](C(=....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1LES - GLC FRU n/a n/a
2 1BQP - MAN C6 H12 O6 C([C@@H]1[....
3 1OFS - SUC C12 H22 O11 C([C@@H]1[....
4 1HKD - GYP C7 H14 O6 CO[C@@H]1[....
5 1LOA - GYP C7 H14 O6 CO[C@@H]1[....
6 1LOC - MDP DAL ZGL n/a n/a
7 1LOB - MMA C7 H14 O6 CO[C@@H]1[....
8 1LOG - MAN BMA NAG n/a n/a
9 1LOD - MUR C9 H17 N O7 C[C@H](C(=....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MAN BMA NAG; Similar ligands found: 271
No: Ligand ECFP6 Tc MDL keys Tc
1 MAN BMA NAG 1 1
2 GLA GAL NAG 1 1
3 NAG GAL GAL NAG 0.852941 0.9375
4 GAL NAG GAL NAG GAL NAG 0.852941 0.918367
5 NDG GAL 0.847458 1
6 NLC 0.847458 1
7 GAL NDG 0.847458 1
8 NAG GAL NAG 0.782609 0.9375
9 NAG BMA MAN MAN MAN MAN 0.721519 1
10 NAG NAG BMA MAN MAN 0.695122 0.9375
11 GLC GAL NAG GAL 0.693333 1
12 LAT NAG GAL 0.693333 1
13 NAG GAL GAL NAG GAL 0.68 0.9375
14 GAL NAG GAL GLC 0.666667 1
15 BGC GAL NAG GAL 0.666667 1
16 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.651163 1
17 GLA GAL GAL 0.636364 0.733333
18 G6S NAG 0.635135 0.725806
19 GAL NGA GLA BGC GAL 0.632911 1
20 NAG FUC 0.632353 0.934783
21 NAG MAN MAN MAN NAG GAL NAG GAL 0.629214 0.918367
22 MAN BMA NAG NAG MAN NAG GAL GAL 0.629214 0.918367
23 GAL NAG GAL BGC 0.625 0.957447
24 CBS CBS 0.623188 0.9375
25 CBS 0.623188 0.9375
26 NAG GDL 0.623188 0.9375
27 NDG NAG 0.623188 0.9375
28 NAG GAL BGC 0.618421 1
29 NAG NAG BMA MAN 0.614458 0.865385
30 GAL BGC NAG GAL 0.61039 1
31 M5G 0.606383 0.9375
32 8VZ 0.602941 0.918367
33 BGC BGC BGC BGC BGC BGC BGC BGC 0.6 0.733333
34 NGA GLA GAL BGC 0.6 1
35 NAG MAN BMA NDG MAN NAG GAL 0.595745 0.918367
36 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.59375 0.9375
37 NAG GAL FUC 0.592105 0.978261
38 FUL GAL NAG 0.592105 0.978261
39 DR2 0.592105 0.978261
40 FUC GAL NAG 0.592105 0.978261
41 FUC GAL NDG 0.592105 0.978261
42 GAL NAG FUC 0.592105 0.978261
43 NDG GAL FUC 0.592105 0.978261
44 NAG NAG BMA MAN MAN NAG GAL NAG 0.589474 0.918367
45 NAG NAG NDG 0.589041 0.918367
46 NAG NAG NDG NAG 0.589041 0.918367
47 NAG NAG NAG NDG 0.589041 0.918367
48 CTO 0.589041 0.918367
49 NAG NAG NAG NAG NAG NAG 0.589041 0.918367
50 NDG NAG NAG NDG 0.589041 0.918367
51 NDG NAG NAG NAG 0.589041 0.918367
52 NAG NAG NAG NAG NAG 0.589041 0.918367
53 NDG NAG NAG 0.589041 0.918367
54 NAG NAG NAG NAG NDG 0.589041 0.918367
55 NAG NAG NAG NAG NAG NAG NAG NAG 0.589041 0.918367
56 A2G GAL 0.57971 1
57 GAL A2G 0.57971 1
58 GAL NGA 0.57971 1
59 FUC BGC GAL NAG GAL 0.579545 0.978261
60 GAL NAG MAN 0.578947 1
61 BGC BGC BGC GLC BGC BGC 0.575758 0.733333
62 GLC BGC BGC BGC BGC BGC BGC 0.575758 0.733333
63 GAL GLC NAG GAL FUC 0.550562 0.978261
64 GLC NAG GAL GAL FUC 0.550562 0.978261
65 FUC GAL NAG GAL BGC 0.550562 0.978261
66 TCG 0.55 0.775862
67 UNU GAL NAG 0.542169 0.918367
68 GLA GAL NAG FUC GAL GLC 0.537634 0.978261
69 NAG BMA NAG MAN MAN NAG NAG 0.536842 0.918367
70 GAL MGC 0.535211 0.957447
71 A2G GAL NAG FUC 0.534091 0.918367
72 FUC GAL NAG A2G 0.534091 0.918367
73 GAL NAG GAL 0.530864 0.957447
74 MDM 0.530303 0.73913
75 GAL MBG 0.530303 0.73913
76 M13 0.530303 0.73913
77 MAN MAN MAN GLC 0.527027 0.733333
78 GLC GAL NAG GAL FUC FUC 0.526882 0.957447
79 BGC GAL NAG GAL FUC FUC 0.526882 0.957447
80 GAL NDG FUC 0.518987 0.978261
81 FUC NDG GAL 0.518987 0.978261
82 HS2 0.518987 0.877551
83 NAG BMA 0.513514 0.897959
84 FUC C4W NAG BMA MAN 0.510204 0.865385
85 NAG NDG BMA 0.506024 0.865385
86 NAG NAG BMA 0.506024 0.865385
87 NGR 0.5 0.733333
88 B2G 0.5 0.733333
89 M3M 0.5 0.733333
90 GLC GAL 0.5 0.733333
91 LAT 0.5 0.733333
92 CBI 0.5 0.733333
93 LBT 0.5 0.733333
94 BGC GAL 0.5 0.733333
95 BMA GAL 0.5 0.733333
96 BGC BMA 0.5 0.733333
97 LB2 0.5 0.733333
98 P3M 0.5 0.6
99 MAN GLC 0.5 0.733333
100 MAL 0.5 0.733333
101 GAL BGC 0.5 0.733333
102 N9S 0.5 0.733333
103 GLA GLA 0.5 0.733333
104 GLA GAL 0.5 0.733333
105 CBK 0.5 0.733333
106 4U2 0.5 0.882353
107 MAB 0.5 0.733333
108 1GN ACY GAL ACY 1GN BGC GAL BGC 0.494505 0.9375
109 ACY 1GN GAL 1GN BGC ACY GAL BGC 0.494505 0.9375
110 FUC BGC GAL NAG 0.494382 0.978261
111 U63 0.492754 0.673469
112 NAG SIA GAL 0.489796 0.865385
113 GCS GCS NAG 0.488372 0.918367
114 NGA GAL BGC 0.4875 1
115 SN5 SN5 0.486842 0.803922
116 GAL NAG GAL FUC 0.482759 0.978261
117 GLA NAG GAL FUC 0.482759 0.978261
118 GLC GAL NAG GAL FUC A2G 0.48 0.918367
119 A2G GAL NAG FUC GAL GLC 0.48 0.918367
120 NAG MBG 0.473684 0.957447
121 BEK GAL NAG 0.473118 0.789474
122 GLC GAL GAL 0.471429 0.733333
123 GLC GLC GLC GLC GLC 0.471429 0.733333
124 GLC BGC BGC BGC BGC BGC 0.471429 0.733333
125 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.471429 0.733333
126 CT3 0.471429 0.733333
127 GLC BGC GLC 0.471429 0.733333
128 GLC GLC BGC 0.471429 0.733333
129 GLC BGC BGC BGC 0.471429 0.733333
130 BGC BGC GLC 0.471429 0.733333
131 BGC BGC BGC 0.471429 0.733333
132 GAL GAL GAL 0.471429 0.733333
133 CTT 0.471429 0.733333
134 BGC GLC GLC GLC 0.471429 0.733333
135 GLC BGC BGC 0.471429 0.733333
136 BGC BGC BGC GLC 0.471429 0.733333
137 GLA GAL GLC 0.471429 0.733333
138 CE5 0.471429 0.733333
139 BGC BGC BGC BGC 0.471429 0.733333
140 BMA MAN BMA 0.471429 0.733333
141 MAN MAN BMA BMA BMA BMA 0.471429 0.733333
142 BGC GLC GLC 0.471429 0.733333
143 BGC GLC GLC GLC GLC GLC GLC 0.471429 0.733333
144 BGC BGC BGC BGC BGC BGC 0.471429 0.733333
145 MAN BMA BMA BMA BMA BMA 0.471429 0.733333
146 BGC BGC BGC BGC BGC 0.471429 0.733333
147 MT7 0.471429 0.733333
148 DXI 0.471429 0.733333
149 GLC BGC BGC BGC BGC 0.471429 0.733333
150 BMA BMA BMA BMA BMA BMA 0.471429 0.733333
151 BMA BMA BMA BMA BMA 0.471429 0.733333
152 MTT 0.471429 0.733333
153 CE8 0.471429 0.733333
154 CE6 0.471429 0.733333
155 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.471429 0.733333
156 GLA GAL BGC 0.471429 0.733333
157 MAN BMA BMA BMA BMA 0.471429 0.733333
158 MAN BMA BMA 0.471429 0.733333
159 CEX 0.471429 0.733333
160 CEY 0.471429 0.733333
161 B4G 0.471429 0.733333
162 BGC GLC GLC GLC GLC 0.471429 0.733333
163 MLR 0.471429 0.733333
164 CTR 0.471429 0.733333
165 BMA BMA BMA 0.471429 0.733333
166 NAG A2G GAL 0.470588 0.9375
167 NAG GAL SIA 0.465347 0.849057
168 4U1 0.465347 0.865385
169 ASG 0.464789 0.66129
170 NAG GAL 0.460526 1
171 GAL NAG 0.460526 1
172 GAL A2G MBN 0.458824 0.957447
173 NGA SER GAL 0.457831 0.882353
174 GAL SER A2G 0.457831 0.882353
175 GAL TNR 0.457831 0.882353
176 A2G SER GAL 0.457831 0.882353
177 NAG GAL NGC 0.457143 0.865385
178 GAL LOG 0.455696 0.803571
179 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.455446 0.918367
180 NAG MAN BMA MAN NAG GAL 0.454545 0.9375
181 BQZ 0.453125 0.666667
182 8VW 0.451613 0.849057
183 NAG NAG BMA MAN MAN MAN MAN 0.448598 0.865385
184 GAL A2G THR 0.447059 0.882353
185 NDG 0.446154 0.888889
186 A2G 0.446154 0.888889
187 NGA 0.446154 0.888889
188 BM3 0.446154 0.888889
189 NAG 0.446154 0.888889
190 HSQ 0.446154 0.888889
191 CGC 0.445946 0.733333
192 MAG FUC GAL 0.445783 0.9375
193 GLA EGA 0.444444 0.73913
194 NAG NAG BMA BMA 0.444444 0.833333
195 DR5 0.442857 0.73913
196 MMA MAN 0.442857 0.73913
197 GAL NDG FUC FUC 0.44186 0.957447
198 FUC NAG GAL FUC 0.44186 0.957447
199 BCW 0.44186 0.957447
200 FUC GAL NAG FUC 0.44186 0.957447
201 FUC GAL NDG FUC 0.44186 0.957447
202 GAL NAG FUC FUC 0.44186 0.957447
203 BDZ 0.44186 0.957447
204 FUC NDG GAL FUC 0.44186 0.957447
205 2M4 0.441176 0.733333
206 LAT GLA 0.441176 0.733333
207 NAG MAN MMA 0.440476 0.957447
208 GAL NGA A2G 0.439024 0.9375
209 NAG NAG FUL BMA MAN MAN NAG GAL 0.4375 0.849057
210 BMA BMA 0.43662 0.680851
211 BGC BGC 0.43662 0.680851
212 NAG A2G 0.435897 0.9375
213 NAG NGA 0.435897 0.9375
214 DR3 0.435294 0.978261
215 BMA MAN MAN MAN 0.434211 0.733333
216 GAL NOK 0.432099 0.8
217 BGC GAL NAG SIA GAL 0.431034 0.849057
218 SIA GAL NAG GAL BGC 0.431034 0.849057
219 SIA GAL NAG GAL GLC 0.431034 0.849057
220 KPM 0.430108 0.846154
221 NAG MAN BMA 0.428571 1
222 GAL A2G NPO 0.426966 0.714286
223 NPO A2G GAL 0.426966 0.714286
224 GLC GLC XYP 0.425 0.733333
225 NAG GCU NAG GCD 0.423077 0.833333
226 BGC BGC ZZ1 0.422222 0.660377
227 4MU MAN MAN 0.422222 0.660377
228 A2G GAL BGC FUC 0.421053 0.978261
229 LGN 0.420561 0.741379
230 IGC 0.420561 0.741379
231 MAN MAN BMA MAN 0.419753 0.733333
232 MAN MAN MAN MAN 0.419753 0.733333
233 BMA BMA MAN 0.418919 0.733333
234 MAN MAN BMA 0.418919 0.733333
235 BGC GLA GAL FUC 0.418605 0.755556
236 FUC NAG GAL 0.418605 0.9
237 FUC C4W NAG BMA 0.418367 0.865385
238 MAN MMA MAN 0.417722 0.73913
239 FUC BGC GAL 0.417722 0.755556
240 FUC GAL NAG GAL FUC 0.414894 0.957447
241 M5S 0.414634 0.733333
242 MAN BMA MAN MAN MAN 0.414634 0.733333
243 CG3 A2G GAL 0.413043 0.703125
244 MBG A2G 0.4125 0.957447
245 A2G MBG 0.4125 0.957447
246 OPM MAN MAN 0.411765 0.653846
247 GAL FUC 0.410959 0.733333
248 MAN BMA MAN 0.410256 0.733333
249 XYT 0.410256 0.6
250 FUC C4W NAG BMA MAN MAN NAG 0.410256 0.865385
251 K5B GMH GMH GLC 0.406593 0.653846
252 SIA GAL NGS 0.405405 0.681818
253 GLA GLA FUC 0.405063 0.755556
254 GLA GAL FUC 0.405063 0.755556
255 FUC GLA GLA 0.405063 0.755556
256 FUC GAL GLA 0.405063 0.755556
257 GAL GAL FUC 0.405063 0.755556
258 8VQ 0.40404 0.849057
259 TRE 0.403226 0.733333
260 NAG BDP 0.402439 0.916667
261 A2G GLA FUC 0.402299 0.978261
262 FUC GLA A2G 0.402299 0.978261
263 FUC GAL A2G 0.402299 0.978261
264 A2G GAL FUC 0.402299 0.978261
265 MAN MAN MAN BMA MAN 0.402299 0.733333
266 NGA GAL FUC 0.402299 0.978261
267 MAL EDO 0.4 0.702128
268 GLA MBG 0.4 0.73913
269 FUC NAG GLA GAL 0.4 0.957447
270 GGD 0.4 0.625
271 G2F BGC BGC BGC BGC BGC 0.4 0.66
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1lob.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1lob.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 1lob.bio4) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 1lob.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 1lob.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 1lob.bio6) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 1lob.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 1LOB; Ligand: MMA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 1lob.bio5) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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