Receptor
PDB id Resolution Class Description Source Keywords
6RY5 1.3 Å EC: 3.2.1.101 CRYSTAL STRUCTURE OF DFG5 FROM CHAETOMIUM THERMOPHILUM IN CO ALPHA-1,6-MANNOBIOSE CHAETOMIUM THERMOPHILUM (STRAIN DSM 14144.50 / IMI 039719) TRANSGLYCOSIDASE FUNGAL CELL WALL PLASMA MEMBRANE GPI-ANCCWP HYDROLASE
Ref.: STRUCTURAL BASE FOR THE TRANSFER OF GPI-ANCHORED GLYCOPROTEINS INTO FUNGAL CELL WALLS. PROC.NATL.ACAD.SCI.USA V. 117 22061 2020
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:502;
A:501;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
40.078 Ca [Ca+2...
PGE A:503;
 Invalid;
 none;
 submit data
150.173 C6 H14 O4 C(COC...
BMA MAN B:1;
 Valid;
 none;
 submit data
n/a n/a
BMA B:1;
 Invalid;
 none;
 submit data
180.156 C6 H12 O6 C([C@...
MAN B:2;
 Invalid;
 none;
 submit data
180.156 C6 H12 O6 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6RY7 1.3 Å EC: 3.2.1.101 CRYSTAL STRUCTURE OF DFG5 FROM CHAETOMIUM THERMOPHILUM IN CO LAMINARIBIOSE CHAETOMIUM THERMOPHILUM (STRAIN DSM 14144.50 / IMI 039719) TRANSGLYCOSIDASE FUNGAL CELL WALL PLASMA MEMBRANE GPI-ANCCWP HYDROLASE
Ref.: STRUCTURAL BASE FOR THE TRANSFER OF GPI-ANCHORED GLYCOPROTEINS INTO FUNGAL CELL WALLS. PROC.NATL.ACAD.SCI.USA V. 117 22061 2020
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6RY1 - MAN C6 H12 O6 C([C@@H]1[....
2 6RY7 - BGC BGC n/a n/a
3 6RY2 - MAN MAN n/a n/a
4 6RY6 - PA1 C6 H13 N O5 C([C@@H]1[....
5 6RY5 - BMA MAN n/a n/a
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6RY1 - MAN C6 H12 O6 C([C@@H]1[....
2 6RY7 - BGC BGC n/a n/a
3 6RY2 - MAN MAN n/a n/a
4 6RY6 - PA1 C6 H13 N O5 C([C@@H]1[....
5 6RY5 - BMA MAN n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6RY1 - MAN C6 H12 O6 C([C@@H]1[....
2 6RY7 - BGC BGC n/a n/a
3 6RY2 - MAN MAN n/a n/a
4 6RY6 - PA1 C6 H13 N O5 C([C@@H]1[....
5 6RY5 - BMA MAN n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: BMA MAN; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: BMA MAN; Similar ligands found: 24
No: Ligand Similarity coefficient
1 BMA MAN 1.0000
2 DMJ MAN 0.9616
3 MMA MAN 0.9487
4 IFM MAN 0.9476
5 BGC GLC 0.9454
6 MAN MAN 0.9430
7 GLC GLC 0.9361
8 GLC BGC 0.9300
9 BMA GLA 0.9290
10 Z4Y MAN 0.9216
11 BGC GLA 0.9176
12 GLC GLA 0.9161
13 7K2 0.9023
14 MSX MAN 0.8992
15 Z9N GLC 0.8941
16 TTZ 0.8841
17 GAL BGC 0.8826
18 7D1 MAN 0.8755
19 MA1 GLC 0.8698
20 SGC GLC 0.8696
21 DMB 0.8680
22 GLC 7LQ 0.8607
23 SER MAN 0.8603
24 FUL 7KT 0.8533
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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