Receptor
PDB id Resolution Class Description Source Keywords
6QTX 1.95 Å EC: 2.3.2.27 CRYSTAL STRUCTURE OF AN ARABIDOPSIS WD40 DOMAIN IN COMPLEX W FLOWERING TRANSCRIPTION FACTOR HOMOLOG ARABIDOPSIS THALIANA COMPLEX PLANT PROTEIN
Ref.: PLANT PHOTORECEPTORS AND THEIR SIGNALING COMPONENTS FOR COP1 BINDING VIA VP PEPTIDE MOTIFS. EMBO J. V. 38 02140 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:703;
A:704;
 Invalid;
Invalid;
 none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
ACE GLY PHE GLY VAL VAL PRO SER PHE TYR B:287;
 Valid;
 Atoms found LESS than expected: % Diff = 0.208;
 submit data
792.935 n/a O=C(N...
SO4 A:702;
A:701;
 Invalid;
Invalid;
 none;
none;
 submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6QTS 1.11 Å EC: 2.3.2.27 CRYSTAL STRUCTURE OF A MUTANT ARABIDOPSIS WD40 DOMAIN IN COM A PHOTORECEPTOR ARABIDOPSIS THALIANA COMPLEX PLANT PROTEIN
Ref.: PLANT PHOTORECEPTORS AND THEIR SIGNALING COMPONENTS FOR COP1 BINDING VIA VP PEPTIDE MOTIFS. EMBO J. V. 38 02140 2019
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 6QTT - ACE GLU LEU LEU MET VAL PRO ASP MET TYR n/a n/a
2 6QTQ - ACE ARG TYR ALA VAL VAL PRO ASP GLU n/a n/a
3 6QTX - ACE GLY PHE GLY VAL VAL PRO SER PHE TYR n/a n/a
4 6QTU - ACE GLU HIS PHE ILE VAL PRO ASP LEU TYR n/a n/a
5 6QTS - ACE ARG TYR ALA VAL VAL PRO ASP GLU n/a n/a
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 6QTT - ACE GLU LEU LEU MET VAL PRO ASP MET TYR n/a n/a
2 6QTQ - ACE ARG TYR ALA VAL VAL PRO ASP GLU n/a n/a
3 6QTX - ACE GLY PHE GLY VAL VAL PRO SER PHE TYR n/a n/a
4 6QTU - ACE GLU HIS PHE ILE VAL PRO ASP LEU TYR n/a n/a
5 6QTS - ACE ARG TYR ALA VAL VAL PRO ASP GLU n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 6QTT - ACE GLU LEU LEU MET VAL PRO ASP MET TYR n/a n/a
2 6QTQ - ACE ARG TYR ALA VAL VAL PRO ASP GLU n/a n/a
3 6QTX - ACE GLY PHE GLY VAL VAL PRO SER PHE TYR n/a n/a
4 6QTU - ACE GLU HIS PHE ILE VAL PRO ASP LEU TYR n/a n/a
5 6QTS - ACE ARG TYR ALA VAL VAL PRO ASP GLU n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ACE GLY PHE GLY VAL VAL PRO SER PHE TYR; Similar ligands found: 86
No: Ligand ECFP6 Tc MDL keys Tc
1 ACE GLY PHE GLY VAL VAL PRO SER PHE TYR 1 1
2 ASP ASP LEU ASP VAL PRO SER PHE LEU GLN 0.540146 0.888889
3 LEU SER SER PRO VAL THR LYS SER PHE 0.507042 0.873016
4 SER PRO ILE VAL PRO SER PHE ASP MET 0.5 0.811594
5 ASP SER GLY PHE SER PHE GLY SER LYS 0.5 0.706897
6 ARG SEP PRO VAL PHE SER 0.496552 0.75
7 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.489362 0.767123
8 THR THR ALA PRO PHE LEU SER GLY LYS 0.483221 0.861538
9 ARG VAL SER PRO SER THR SER TYR THR PRO 0.480916 0.873016
10 GLN VAL PRO SER ASP PRO TYR ASN TYR 0.475524 0.835821
11 ARG THR PHE SER PRO THR TYR GLY LEU 0.474026 0.805556
12 ILE THR ASP GLN VAL PRO PHE SER VAL 0.466667 0.875
13 LEU PHE GLY TYR PRO VAL TYR VAL 0.465278 0.830769
14 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.464968 0.8
15 ACE GLU HIS PHE ILE VAL PRO ASP LEU TYR 0.460526 0.776119
16 PRO ALA PRO PHE ALA SER ALA 0.455882 0.870968
17 ASP ASP ASP MET GLY PHE GLY LEU PHE ASP 0.454545 0.672131
18 ARG PRO PRO GLY PHE SER PRO PHE ALA 0.453947 0.808824
19 GLY GLN VAL PRO PHE SER LYS GLU GLU CYS 0.450331 0.875
20 ALA LEU TRP GLY PHE VAL PRO VAL LEU 0.449367 0.815385
21 ASN TRP SER HIS PRO GLN PHE GLU LYS 0.448529 0.857143
22 ACE GLY LYS SER PHE SER LYS PRO ARG 0.447552 0.859375
23 PHE LEU PRO SER ASP PHE PHE PRO SER VAL 0.447552 0.90625
24 ILE PRO ALA TYR GLY VAL LEU THR ILE 0.446667 0.833333
25 LEU LEU PHE GLY PHE PRO VAL TYR VAL 0.446667 0.830769
26 LEU LEU PHE GLY TYR PRO VAL TYR VAL 0.446667 0.830769
27 PRO ALA PRO PHE PRO ALA NH2 0.446281 0.758065
28 ILE MET ASP GLN VAL PRO PHE SER VAL 0.445161 0.835821
29 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.444444 0.80597
30 PHE ALA PRO GLY PHE PHE PRO TYR LEU 0.44 0.80597
31 DPN PRO DAR DTH NH2 0.439394 0.787879
32 ACE PRO ALA PRO PHE ALA ALA ALA ALA NH2 0.436975 0.714286
33 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.436464 0.76
34 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.436364 0.811594
35 LEU PRO SER PHE GLU THR ALA LEU 0.435374 0.888889
36 ALA THR PRO PHE GLN GLU 0.434783 0.852459
37 ASP PHE GLU GLU ILE PRO GLU GLU TYS 0.434211 0.626506
38 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.433962 0.797101
39 PHE GLN PRO GLN ASN GLY GLN PHE ILE 0.433333 0.84375
40 ALA DAL PRO PHE NIT 0.430769 0.671233
41 ASP LEU PRO PHE 0.429688 0.836066
42 GLN LEU SER PRO PHE PRO PHE ASP LEU 0.42953 0.890625
43 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.428571 0.785714
44 ASP PHE GLU GLU ILE PRO GLY GLU PTR 0.428571 0.706667
45 ARG PRO MET THR PHE LYS GLY ALA LEU 0.428571 0.743243
46 ARG PHE PRO LEU THR PHE GLY TRP 0.428571 0.791667
47 ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 0.426829 0.785714
48 SER SER GLY LYS VAL PRO LEU SER 0.423358 0.857143
49 MAA LYS PRO PHE 0.423077 0.786885
50 GLY TYR GLU ASN PRO THR TYR LYS PHE PHE 0.42236 0.820895
51 ASP PHE GLU GLU ILE PRO GLY GLU TYR LEU 0.42236 0.820895
52 SER SER GLY LYS VAL PRO LEU 0.422222 0.870968
53 THR GLY VAL ALA LEU THR PRO PRO SER 0.42069 0.84375
54 ARG GLN PHE GLY PRO ASP PHE PRO THR ILE 0.419162 0.777778
55 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.419162 0.774648
56 DPN PRO DAR ILE NH2 0.41791 0.716418
57 TRP ASP ILE PRO PHE 0.417323 0.806452
58 ARG PRO PRO GLY PHE 0.416058 0.691176
59 ARG PRO PRO GLY PHE SER PRO PHE ARG 0.416058 0.691176
60 ARG GLY PRO GLY CYS ALA PHE VAL THR ILE 0.415663 0.774648
61 PRO ALA PRO PHE ALA ALA ALA 0.414815 0.774194
62 GLU TYR LEU GLY LEU ASP VAL PRO VAL 0.414474 0.815385
63 LEU PRO PHE GLU LEU ARG GLY HIS LEU VAL 0.413174 0.732394
64 BE2 GLY PHE GLY PRO PHE GLY PHE ALA 0.413043 0.809524
65 ALA PHE ARG ILE PRO LEU THR ARG 0.412903 0.760563
66 ARG TYR PRO LEU THR PHE GLY TRP 0.411429 0.77027
67 PHE ASN ARG PRO VAL 0.411348 0.791045
68 THR PRO PRO SER PRO PHE 0.410853 0.8125
69 ACE GLU LEU LEU MET VAL PRO ASP MET TYR 0.410596 0.753623
70 GLY THR SER SER PRO SER ALA ASP 0.409091 0.83871
71 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.408537 0.876923
72 SER ILE TYR PHE TPO PRO GLU LEU TYR ASP 0.408284 0.783784
73 ASP PHE GLU GLU ILE PRO GLU GLU TYS LEU 0.405882 0.658537
74 SER SER TYR ARG ARG PRO VAL GLY ILE 0.405063 0.767123
75 ASN TYR THR PRO GLY PRO GLY THR ARG PHE 0.404762 0.767123
76 LEU ASN PHE PRO ILE SER PRO 0.404255 0.848485
77 ARG VAL ALA SER PRO THR SER GLY VAL 0.40411 0.794118
78 SER THR SEP PRO THR PHE ASN LYS 0.403727 0.785714
79 TYR PRO SER LYS PRO ASP ASN PRO GLY GLU 0.403101 0.8125
80 ARG PRO GLY ASN PHE LEU GLN SER SER PRO 0.402685 0.806452
81 PHE PRO ARG 0.401575 0.692308
82 MET LEU LEU SER VAL PRO LEU LEU LEU GLY 0.40146 0.84375
83 PHE GLU ASP ASN PHE VAL PRO 0.401408 0.873016
84 THR THR ALA PRO SER LEU SER GLY LYS 0.401361 0.830769
85 VAL MET ALA PRO ARG THR LEU PHE LEU 0.401235 0.72973
86 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.401235 0.774648
Similar Ligands (3D)
Ligand no: 1; Ligand: ACE GLY PHE GLY VAL VAL PRO SER PHE TYR; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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