Receptor
PDB id Resolution Class Description Source Keywords
6HPG 2 Å NON-ENZYME: OTHER ARABIDOPSIS OM64 TPR DOMAIN ARABIDOPSIS THALIANA TETRATRICO-PEPTIDE-REPEAT MITOCHONDRIA PROTEIN IMPORT ARATHALIANA PLANT PROTEIN
Ref.: PHOSPHORYLATION OF THE OUTER MEMBRANE MITOCHONDRIAL OM64 INFLUENCES PROTEIN IMPORT INTO MITOCHONDRIA. MITOCHONDRION V. 44 93 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GLY SER LYS MET GLU GLU VAL ASP D:0;
A:0;
F:1;
B:0;
E:1;
C:1;
 Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
none;
none;
 Kd = 3.17 uM
891.954 n/a S(CCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6HPG 2 Å NON-ENZYME: OTHER ARABIDOPSIS OM64 TPR DOMAIN ARABIDOPSIS THALIANA TETRATRICO-PEPTIDE-REPEAT MITOCHONDRIA PROTEIN IMPORT ARATHALIANA PLANT PROTEIN
Ref.: PHOSPHORYLATION OF THE OUTER MEMBRANE MITOCHONDRIAL OM64 INFLUENCES PROTEIN IMPORT INTO MITOCHONDRIA. MITOCHONDRION V. 44 93 2019
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 6Q3Q Kd = 35.2 uM GLY SER LYS MET GLU GLU VAL ASP n/a n/a
2 6HPG Kd = 3.17 uM GLY SER LYS MET GLU GLU VAL ASP n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 6Q3Q Kd = 35.2 uM GLY SER LYS MET GLU GLU VAL ASP n/a n/a
2 6HPG Kd = 3.17 uM GLY SER LYS MET GLU GLU VAL ASP n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6Q3Q Kd = 35.2 uM GLY SER LYS MET GLU GLU VAL ASP n/a n/a
2 6HPG Kd = 3.17 uM GLY SER LYS MET GLU GLU VAL ASP n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GLY SER LYS MET GLU GLU VAL ASP; Similar ligands found: 40
No: Ligand ECFP6 Tc MDL keys Tc
1 GLY SER LYS MET GLU GLU VAL ASP 1 1
2 ASP THR GLU MET GLU GLU VAL ASP 0.651685 0.826923
3 ACE MET GLU GLU VAL ASP 0.632184 0.773585
4 ALA LYS GLU LYS SER ASP 0.588889 0.846154
5 SER ARG MET GLU GLU VAL ASP 0.582524 0.90566
6 ACE VAL LYS GLU SER LEU VAL 0.524752 0.865385
7 LEU PRO PRO PRO GLU SER GLU SER LYS VAL 0.524272 0.824561
8 ALA SER ASN GLU ASP MET GLU THR MET 0.490741 0.854545
9 THR LYS CYS VAL VAL MET 0.485437 0.90566
10 ALA SER ASN GLU ASN MET GLU THR MET 0.481132 0.854545
11 SER LEU LYS LEU MET THR THR VAL 0.476636 0.924528
12 ACE MET GLU GLU VAL PHE 0.466667 0.714286
13 PRO THR VAL GLU GLU VAL ASP 0.462264 0.775862
14 GLN ILE LYS VAL ARG VAL ASP MET VAL 0.459677 0.779661
15 ACE MET LEU SER VAL GLU GLU GLU GLY 0.458716 0.90566
16 VAL GLN GLN GLU SER SER PHE VAL MET 0.449153 0.872727
17 GLY ASP GLU VAL LYS VAL PHE ARG 0.44186 0.688525
18 ALA GLU LYS ASP GLU LEU 0.44 0.807692
19 GLY CYS SER VAL SER LYS LYS LYS MYR 0.436975 0.925926
20 LYS CYS VAL VAL MET 0.435644 0.846154
21 LYS ARG GLU ALA ILE VAL LYS ALA ASP GLU 0.431034 0.792453
22 LEU PRO PHE GLU LYS SER THR VAL MET 0.430556 0.787879
23 LYS MET LYS 0.430108 0.807692
24 ALA SER ASN GLU ASN ALA GLU THR MET 0.426087 0.854545
25 ALA GLU ASP ASP VAL GLU 0.42268 0.698113
26 ALA SER ASN GLU ASN ILE GLU THR MET 0.418803 0.839286
27 THR ASN GLU TYR LYS VAL 0.417391 0.7
28 THR LYS CYS VAL PHE MET 0.416667 0.857143
29 GLU GLU ILE ASP VAL VAL SER VAL 0.414414 0.830189
30 ALA ILE PHE GLN SER SER MET THR LYS 0.412214 0.877193
31 VAL THR THR ASP ILE GLN VAL LYS VAL 0.411765 0.833333
32 GLN ALA SER GLN GLU VAL LYS ASN TRP 0.411348 0.71875
33 ILE LEU ASN ALA MET ILE VAL LYS ILE 0.41129 0.851852
34 ILE LEU MET GLU HIS ILE HIS LYS LEU 0.409091 0.703125
35 GLY CYS VAL LEU SER 0.408163 0.826923
36 GLY ALA ASP GLY VAL GLY LYS SER ALA 0.40678 0.867925
37 SER LEU LYS ILE ASP ASN MET ASP 0.404762 0.909091
38 CYS THR GLU LEU LYS LEU SER ASP TYR 0.401515 0.79661
39 HIS MET THR GLU VAL VAL ARG ARG CYS 0.40146 0.720588
40 ACE ASP GLU VAL ASP 0QE 0.4 0.672727
Similar Ligands (3D)
Ligand no: 1; Ligand: GLY SER LYS MET GLU GLU VAL ASP; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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