Receptor
PDB id Resolution Class Description Source Keywords
4Z0U 2 Å EC: 3.1.26.4 RNASE HI/SSB-CT COMPLEX ESCHERICHIA COLI O139:H28 RIBONUCLEASE PEPTIDE COMPLEX HYDROLASE-PEPTIDE COMPLEX
Ref.: INTERACTION WITH SINGLE-STRANDED DNA-BINDING PROTEI STIMULATES ESCHERICHIA COLI RIBONUCLEASE HI ENZYMAT ACTIVITY. J.BIOL.CHEM. V. 290 14626 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
TRP MET ASP PHE ASP ASP ASP ILE PRO PHE E:174;
D:174;
Valid;
Valid;
Atoms found LESS than expected: % Diff = 0.62;
Atoms found LESS than expected: % Diff = 0.62;
Kd = 2 uM
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4Z0U 2 Å EC: 3.1.26.4 RNASE HI/SSB-CT COMPLEX ESCHERICHIA COLI O139:H28 RIBONUCLEASE PEPTIDE COMPLEX HYDROLASE-PEPTIDE COMPLEX
Ref.: INTERACTION WITH SINGLE-STRANDED DNA-BINDING PROTEI STIMULATES ESCHERICHIA COLI RIBONUCLEASE HI ENZYMAT ACTIVITY. J.BIOL.CHEM. V. 290 14626 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4Z0U Kd = 2 uM TRP MET ASP PHE ASP ASP ASP ILE PRO PHE n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4Z0U Kd = 2 uM TRP MET ASP PHE ASP ASP ASP ILE PRO PHE n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4Z0U Kd = 2 uM TRP MET ASP PHE ASP ASP ASP ILE PRO PHE n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: TRP MET ASP PHE ASP ASP ASP ILE PRO PHE; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: TRP MET ASP PHE ASP ASP ASP ILE PRO PHE; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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