Receptor
PDB id Resolution Class Description Source Keywords
4I67 2.33 Å EC: 3.6.4.13 CRYSTAL STRUCTURE OF THE RRM DOMAIN OF RNA HELICASE HERA FRO THERMOPHILUS IN COMPLEX WITH GGGC RNA THERMUS THERMOPHILUS UNWINDING ATPASE HEAT RESISTANT RNA RECOGNITION MOTIF RNBINDING DEAD BOX PROTEIN HYDROLASE-RNA COMPLEX
Ref.: RECOGNITION OF TWO DISTINCT ELEMENTS IN THE RNA SUB THE RNA-BINDING DOMAIN OF THE T. THERMOPHILUS DEAD HELICASE HERA. NUCLEIC ACIDS RES. V. 41 6259 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
G G G RPC B:1;
Valid;
none;
submit data
1431.74 n/a P(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4I67 2.33 Å EC: 3.6.4.13 CRYSTAL STRUCTURE OF THE RRM DOMAIN OF RNA HELICASE HERA FRO THERMOPHILUS IN COMPLEX WITH GGGC RNA THERMUS THERMOPHILUS UNWINDING ATPASE HEAT RESISTANT RNA RECOGNITION MOTIF RNBINDING DEAD BOX PROTEIN HYDROLASE-RNA COMPLEX
Ref.: RECOGNITION OF TWO DISTINCT ELEMENTS IN THE RNA SUB THE RNA-BINDING DOMAIN OF THE T. THERMOPHILUS DEAD HELICASE HERA. NUCLEIC ACIDS RES. V. 41 6259 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 4I67 - G G G RPC n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 4I67 - G G G RPC n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 4I67 - G G G RPC n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: G G G RPC; Similar ligands found: 87
No: Ligand ECFP6 Tc MDL keys Tc
1 G G G RPC 1 1
2 A G C C 0.882883 0.961538
3 G C C C 0.789916 0.949367
4 G G G C 0.762712 0.962025
5 G C 0.756522 0.949367
6 G U 0.612903 0.949367
7 U A G G 0.606299 0.935897
8 G G 0.601695 0.924051
9 A G 0.598425 0.935897
10 U A C C 0.596899 0.935897
11 CG2 0.595238 0.91358
12 GCP G 0.594828 0.922078
13 A G U U 0.587413 0.962025
14 A G U 0.574468 0.962025
15 APC G U 0.572519 0.935897
16 C C 0.567568 0.846154
17 G A A A 0.561538 0.924051
18 GPC 0.55303 0.880952
19 A C A C 0.548872 0.924051
20 G3D 0.547826 0.886076
21 G4P 0.538462 0.886076
22 C C C C 0.525862 0.835443
23 A U C C 0.524476 0.924051
24 CTP C C C C 0.519685 0.881579
25 DC DG 0.518797 0.914634
26 3GP 0.509091 0.897436
27 0O2 0.508197 0.886076
28 G U34 0.492537 0.9375
29 ALF 5GP 0.491525 0.845238
30 DG DC 0.485915 0.902439
31 U2G 0.485075 0.91358
32 5GP 0.473684 0.886076
33 DC DG DA DC 0.473684 0.925926
34 G 0.473684 0.886076
35 UCG 0.472222 0.936709
36 ALF GDP 0.467742 0.845238
37 GDP AF3 0.467742 0.845238
38 GDP ALF 0.467742 0.845238
39 GDP 0.466102 0.875
40 GNH 0.462185 0.864198
41 GPG 0.460317 0.888889
42 GSP 0.459016 0.833333
43 GP3 0.457627 0.9
44 CGP 0.456522 0.891566
45 2GP 0.45614 0.8625
46 GP2 0.453782 0.843373
47 GMP 0.453704 0.7875
48 U A A U 0.44898 0.911392
49 GTP 0.442623 0.875
50 GMV 0.442623 0.853659
51 DC DG DT DA 0.440476 0.904762
52 DG DA DC DG 0.440252 0.926829
53 GAV 0.44 0.843373
54 G1R 0.439024 0.864198
55 GCP 0.439024 0.853659
56 U U U U 0.438017 0.807692
57 GDP 7MG 0.43609 0.9125
58 DA DC DG DA 0.435583 0.914634
59 GNP 0.435484 0.853659
60 G2P 0.435484 0.843373
61 9GM 0.435484 0.853659
62 DT DA DC DG 0.434524 0.904762
63 G2R 0.429688 0.843373
64 DG DG 0.426357 0.890244
65 GDC 0.424242 0.865854
66 GKE 0.424242 0.865854
67 GDD 0.424242 0.865854
68 UTP U U U 0.422764 0.815789
69 JB2 0.422222 0.865854
70 BGO 0.421429 0.878049
71 U A 0.42069 0.911392
72 C3P 0.418182 0.833333
73 6CK 0.41791 0.845238
74 Y9Z 0.413534 0.795455
75 CSV 0.412214 0.783133
76 CSQ 0.412214 0.783133
77 NGD 0.411348 0.9125
78 GFB 0.410448 0.865854
79 GDR 0.410448 0.865854
80 GDX 0.408759 0.876543
81 3PD UM3 0.408451 0.9375
82 YGP 0.406015 0.879518
83 A U 0.404255 0.898734
84 GGM 0.402778 0.857143
85 GKD 0.40146 0.865854
86 DA DU DG DA 0.401408 0.902439
87 GTG 0.4 0.890244
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4I67; Ligand: G G G RPC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4i67.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
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