Receptor
PDB id Resolution Class Description Source Keywords
4BTB 1.9 Å EC: 1.14.11.2 CRYSTAL STRUCTURE OF THE PEPTIDE(PRO)9 BOUND COMPLEX OF N-TE DOMAIN AND PEPTIDE SUBSTRATE BINDING DOMAIN OF PROLYL-4 HYD( RESIDUES 1-238) TYPE I FROM HUMAN HOMO SAPIENS OXIDOREDUCTASE TETRATRICOPEPTIDE REPEAT MOTIF COILED-COILRICH PEPTIDE
Ref.: THE STRUCTURAL MOTIFS FOR SUBSTRATE BINDING AND DIM OF THE ALPHA SUBUNIT OF COLLAGEN PROLYL 4-HYDROXYLA STRUCTURE V. 21 2107 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PRO PRO PRO PRO PRO PRO PRO PRO PRO C:0;
Valid;
none;
Kd = 9.8 uM
877.077 n/a O=C(N...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4BTB 1.9 Å EC: 1.14.11.2 CRYSTAL STRUCTURE OF THE PEPTIDE(PRO)9 BOUND COMPLEX OF N-TE DOMAIN AND PEPTIDE SUBSTRATE BINDING DOMAIN OF PROLYL-4 HYD( RESIDUES 1-238) TYPE I FROM HUMAN HOMO SAPIENS OXIDOREDUCTASE TETRATRICOPEPTIDE REPEAT MOTIF COILED-COILRICH PEPTIDE
Ref.: THE STRUCTURAL MOTIFS FOR SUBSTRATE BINDING AND DIM OF THE ALPHA SUBUNIT OF COLLAGEN PROLYL 4-HYDROXYLA STRUCTURE V. 21 2107 2013
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4BT9 Kd = 143.5 uM PRO PRO GLY PRO PRO GLY PRO PRO GLY n/a n/a
2 4BTB Kd = 9.8 uM PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4BT9 Kd = 143.5 uM PRO PRO GLY PRO PRO GLY PRO PRO GLY n/a n/a
2 4BTB Kd = 9.8 uM PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4BT9 Kd = 143.5 uM PRO PRO GLY PRO PRO GLY PRO PRO GLY n/a n/a
2 4BTB Kd = 9.8 uM PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PRO PRO PRO PRO PRO PRO PRO PRO PRO; Similar ligands found: 14
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4BTB; Ligand: PRO PRO PRO PRO PRO PRO PRO PRO PRO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4btb.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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