-->
Receptor
PDB id Resolution Class Description Source Keywords
1PEA 2.1 Å NON-ENZYME: TRANSCRIPT_TRANSLATE AMIDE RECEPTOR/NEGATIVE REGULATOR OF THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA (AMIC) COMPLEXED WITH ACETAMIDE PSEUDOMONAS AERUGINOSA GENE REGULATOR RECEPTOR BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF AMIC: THE CONTROLLER OF TRANSCRIPTION ANTITERMINATION IN THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA. EMBO J. V. 13 5810 1994
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACM A:386;
Valid;
none;
submit data
59.067 C2 H5 N O CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1PEA 2.1 Å NON-ENZYME: TRANSCRIPT_TRANSLATE AMIDE RECEPTOR/NEGATIVE REGULATOR OF THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA (AMIC) COMPLEXED WITH ACETAMIDE PSEUDOMONAS AERUGINOSA GENE REGULATOR RECEPTOR BINDING PROTEIN
Ref.: CRYSTAL STRUCTURE OF AMIC: THE CONTROLLER OF TRANSCRIPTION ANTITERMINATION IN THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA. EMBO J. V. 13 5810 1994
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 291 families.
1 1PEA - ACM C2 H5 N O CC(=O)N
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 247 families.
1 1PEA - ACM C2 H5 N O CC(=O)N
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 1PEA - ACM C2 H5 N O CC(=O)N
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ACM; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 ACM 1 1
2 PYM 0.636364 0.6875
3 ROP 0.5 0.6875
4 TAY 0.461538 0.6875
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1PEA; Ligand: ACM; Similar sites found with APoc: 33
This union binding pocket(no: 1) in the query (biounit: 1pea.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5Z99 SLB 1.2987
2 3EBL GA4 1.64384
3 1HSL HIS 1.68067
4 2ZRU FMN 1.90217
5 4GYS MLI 2.07792
6 3ZS7 ATP 2.33333
7 4CP8 MLI 2.85714
8 3JQ3 ADP 3.00546
9 4K26 SFF 3.26087
10 2UZ1 TPP 3.37662
11 4B74 1LH 3.37662
12 4WOH 4NP 3.61446
13 5FBK TCR 3.63636
14 5XLS URA 3.8961
15 5O96 SAM 4.08163
16 1NRJ GTP 4.58716
17 1TLG GAL 4.8
18 4R74 F6P 5.29595
19 5K8P 6R8 5.45455
20 1VLJ NAP 5.97403
21 4IXH IMP 6.09418
22 1Y60 H4M 7.10059
23 3F81 STT 8.19672
24 1I52 CTP 8.47458
25 1B7A OPE 8.60215
26 1XK9 P34 9.30233
27 3IP6 PRO 9.55056
28 4BUY F37 10.4167
29 1Z17 ILE 10.4651
30 1HFU NAG NDG 10.9091
31 2Z3U CRR 12
32 1WG8 SAM 15.0877
33 4EVQ PHB 33.6
Pocket No.: 2; Query (leader) PDB : 1PEA; Ligand: ACM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1pea.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback