Receptor
PDB id Resolution Class Description Source Keywords
1FMB 1.8 Å EC: 3.4.23.16 EIAV PROTEASE COMPLEXED WITH THE INHIBITOR HBY-793 EQUINE INFECTIOUS ANEMIA VIRUS HYDROLASE (ACID PROTEINASE) RNA-DIRECTED DNA POLYMERASE ASPROTEASE ENDONUCLEASE POLYPROTEIN
Ref.: STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS PROTEIN COMPLEXED WITH AN INHIBITOR. PROTEIN SCI. V. 5 1453 1996
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HYB A:201;
Valid;
none;
Ki = 0.1 nM
566.751 C32 H42 N2 O5 S CC(C)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1FMB 1.8 Å EC: 3.4.23.16 EIAV PROTEASE COMPLEXED WITH THE INHIBITOR HBY-793 EQUINE INFECTIOUS ANEMIA VIRUS HYDROLASE (ACID PROTEINASE) RNA-DIRECTED DNA POLYMERASE ASPROTEASE ENDONUCLEASE POLYPROTEIN
Ref.: STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS PROTEIN COMPLEXED WITH AN INHIBITOR. PROTEIN SCI. V. 5 1453 1996
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 22 families.
1 1FMB Ki = 0.1 nM HYB C32 H42 N2 O5 S CC(C)[C@@H....
2 2FMB Ki = 2 nM LP1 C45 H58 N6 O7 CC[C@@H](C....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 15 families.
1 1FMB Ki = 0.1 nM HYB C32 H42 N2 O5 S CC(C)[C@@H....
2 2FMB Ki = 2 nM LP1 C45 H58 N6 O7 CC[C@@H](C....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 15 families.
1 1FMB Ki = 0.1 nM HYB C32 H42 N2 O5 S CC(C)[C@@H....
2 2FMB Ki = 2 nM LP1 C45 H58 N6 O7 CC[C@@H](C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HYB; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 HYB 1 1
2 BAY 0.744681 0.885246
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1FMB; Ligand: HYB; Similar sites found with APoc: 1
This union binding pocket(no: 1) in the query (biounit: 1fmb.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5T2Z 017 46.1538
Pocket No.: 2; Query (leader) PDB : 1FMB; Ligand: HYB; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 1fmb.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
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