Receptor
PDB id Resolution Class Description Source Keywords
6XTZ 2.21 Å NON-ENZYME: OTHER STRUCTURE OF DALLY-LIKE PROTEIN IN COMPLEX WITH O-PALMITOLEO DROSOPHILA MELANOGASTER GLYPICANS GPI-ANCHORED WNT PALMITOLEATE SIGNALING PROTEI
Ref.: GLYPICANS SHIELD THE WNT LIPID MOIETY TO ENABLE SIG AT A DISTANCE. NATURE V. 585 85 2020
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG A:701;
 Invalid;
 none;
 submit data
221.208 C8 H15 N O6 CC(=O...
GOL A:704;
A:707;
A:705;
A:706;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
TRS A:702;
 Invalid;
 none;
 submit data
122.143 C4 H12 N O3 C(C(C...
O18 A:703;
 Valid;
 none;
 submit data
325.486 C19 H35 N O3 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6XTZ 2.21 Å NON-ENZYME: OTHER STRUCTURE OF DALLY-LIKE PROTEIN IN COMPLEX WITH O-PALMITOLEO DROSOPHILA MELANOGASTER GLYPICANS GPI-ANCHORED WNT PALMITOLEATE SIGNALING PROTEI
Ref.: GLYPICANS SHIELD THE WNT LIPID MOIETY TO ENABLE SIG AT A DISTANCE. NATURE V. 585 85 2020
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 6XTZ - O18 C19 H35 N O3 CCCCCC/C=C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 6XTZ - O18 C19 H35 N O3 CCCCCC/C=C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6XTZ - O18 C19 H35 N O3 CCCCCC/C=C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: O18; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 O18 1 1
2 CYS HIS GLY VAL SER GLY SER CYS PAM 0.696429 0.969697
3 P50 0.565789 0.64
4 S12 0.527027 0.64
5 TGL 0.45 0.605263
6 VA 0.423729 0.636364
7 BQ9 0.402597 0.6
8 8ND 0.4 0.731707
Similar Ligands (3D)
Ligand no: 1; Ligand: O18; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6XTZ; Ligand: O18; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6xtz.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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