Receptor
PDB id Resolution Class Description Source Keywords
6QNS 2.4 Å EC: 3.4.24.69 CRYSTAL STRUCTURE OF THE BINDING DOMAIN OF BOTULINUM NEUROTO MUTANT I1248W/V1249W IN COMPLEX WITH HUMAN SYNAPTOTAGMIN 1 R ECEPTORS CLOSTRIDIUM BOTULINUM BOTULINUM TOXIN TOXIN
Ref.: CHARACTERIZATION OF A MEMBRANE BINDING LOOP LEADS T ENGINEERING BOTULINUM NEUROTOXIN B WITH IMPROVED TH EFFICACY. PLOS BIOL. V. 18 00618 2020
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BGC GAL SIA NGA GAL SIA B:1;
 Invalid;
 none;
 submit data
1288.13 n/a O=C(N...
BGC GAL NGA GAL SIA SIA :0;
B:1;
 Invalid;
Valid;
 none;
none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6QNS 2.4 Å EC: 3.4.24.69 CRYSTAL STRUCTURE OF THE BINDING DOMAIN OF BOTULINUM NEUROTO MUTANT I1248W/V1249W IN COMPLEX WITH HUMAN SYNAPTOTAGMIN 1 R ECEPTORS CLOSTRIDIUM BOTULINUM BOTULINUM TOXIN TOXIN
Ref.: CHARACTERIZATION OF A MEMBRANE BINDING LOOP LEADS T ENGINEERING BOTULINUM NEUROTOXIN B WITH IMPROVED TH EFFICACY. PLOS BIOL. V. 18 00618 2020
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 6QNS - BGC GAL NGA GAL SIA SIA n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 6QNS - BGC GAL NGA GAL SIA SIA n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 6QNS - BGC GAL NGA GAL SIA SIA n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: BGC GAL NGA GAL SIA SIA; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: BGC GAL NGA GAL SIA SIA; Similar ligands found: 1
No: Ligand Similarity coefficient
1 BGC GAL NGA GAL SIA SIA 0.9997
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
Feedback