Receptor
PDB id Resolution Class Description Source Keywords
6I0T 2 Å EC: 2.7.7.52 CRYSTAL STRUCTURE OF DMTAILOR IN COMPLEX WITH GPU DROSOPHILA MELANOGASTER TERMINAL URIDYL TRANSFERASE NUCLEOTIDYL TRANSFERASE TRANSF
Ref.: STRUCTURAL BASIS FOR ACCEPTOR RNA SUBSTRATE SELECTI THE 3' TERMINAL URIDYLYL TRANSFERASE TAILOR. NUCLEIC ACIDS RES. V. 47 1030 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
G U B:1;
Valid;
Atoms found LESS than expected: % Diff = 0;
submit data
588.403 n/a P(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5Z4A 1.64 Å EC: 2.7.7.52 STRUCTURE OF TAILOR IN COMPLEX WITH AGU RNA DROSOPHILA MELANOGASTER TERMINAL URIDYLYLTRANSFERASE TRANSFERASE-RNA COMPLEX
Ref.: STRUCTURAL INSIGHTS INTO A UNIQUE PREFERENCE FOR 3' GUANINE OF MIRTRON IN DROSOPHILA TUTASE TAILOR. NUCLEIC ACIDS RES. V. 47 495 2019
Members (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5Z4M - UTP C9 H15 N2 O15 P3 C1=CN(C(=O....
2 5Z4J - U U U U n/a n/a
3 5Z4A - A G U n/a n/a
4 6I0S - 2KH C9 H16 N3 O14 P3 C1=CN(C(=O....
5 6I0T - G U n/a n/a
6 5Z4D - A G U U n/a n/a
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5Z4M - UTP C9 H15 N2 O15 P3 C1=CN(C(=O....
2 5Z4J - U U U U n/a n/a
3 5Z4A - A G U n/a n/a
4 6I0S - 2KH C9 H16 N3 O14 P3 C1=CN(C(=O....
5 6I0T - G U n/a n/a
6 5Z4D - A G U U n/a n/a
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5Z4M - UTP C9 H15 N2 O15 P3 C1=CN(C(=O....
2 5Z4J - U U U U n/a n/a
3 5Z4A - A G U n/a n/a
4 6I0S - 2KH C9 H16 N3 O14 P3 C1=CN(C(=O....
5 6I0T - G U n/a n/a
6 5Z4D - A G U U n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: G U ; Similar ligands found: 137
No: Ligand ECFP6 Tc MDL keys Tc
1 G U 1 1
2 A G U 0.818182 0.987342
3 G C 0.801802 1
4 A G U U 0.785714 0.987342
5 G U34 0.721739 0.987342
6 A U 0.689655 0.924051
7 G G G C 0.688525 0.9625
8 A G C C 0.682927 0.987179
9 G C C C 0.661417 0.974684
10 U2G 0.628099 0.9625
11 G G 0.626087 0.925
12 G G G RPC 0.612903 0.949367
13 A U C C 0.6 0.949367
14 G A A A 0.595238 0.949367
15 U A A U 0.586466 0.9125
16 3GP 0.576923 0.898734
17 U U 0.5625 0.822785
18 A G 0.55814 0.936709
19 U A G G 0.553846 0.936709
20 U A 0.545455 0.9125
21 UCG 0.544118 0.9375
22 G3D 0.54386 0.8875
23 ALF 5GP 0.539823 0.869048
24 GPC 0.537879 0.927711
25 GCP G 0.525 0.898734
26 5GP 0.522936 0.911392
27 G 0.522936 0.911392
28 G4P 0.521368 0.8875
29 CG2 0.519084 0.9625
30 UDP UDP 0.514286 0.807692
31 GDP 0.513274 0.9
32 GP2 0.513274 0.86747
33 ALF GDP 0.512605 0.869048
34 GDP AF3 0.512605 0.869048
35 GDP ALF 0.512605 0.869048
36 APC G U 0.511111 0.888889
37 GPG 0.504132 0.91358
38 0O2 0.504132 0.8875
39 A C A C 0.5 0.949367
40 3PD UM3 0.5 0.938272
41 GCP 0.495726 0.878049
42 GNH 0.495652 0.888889
43 GSP 0.491525 0.857143
44 G2P 0.491525 0.86747
45 GP3 0.491228 0.901235
46 UPU 0.491071 0.810127
47 GMP 0.490385 0.835443
48 GKE 0.488 0.91358
49 GDD 0.488 0.91358
50 GDC 0.488 0.91358
51 CSQ 0.487805 0.829268
52 CSV 0.487805 0.829268
53 GTP 0.487179 0.9
54 GAV 0.483333 0.86747
55 2GP 0.477477 0.8875
56 4TC 0.477273 0.855422
57 GDP 7MG 0.476562 0.91358
58 GMV 0.474576 0.878049
59 UP5 0.473282 0.876543
60 UDP 0.472222 0.7875
61 U5P 0.471154 0.797468
62 U 0.471154 0.797468
63 G1R 0.470588 0.888889
64 DA DU DG DA 0.470149 0.880952
65 U U U U 0.470085 0.810127
66 GNP 0.466667 0.878049
67 9GM 0.466667 0.878049
68 APU 0.462687 0.9
69 JB2 0.461538 0.890244
70 G2R 0.459677 0.86747
71 C C C C 0.458333 0.884615
72 U A C C 0.457143 0.936709
73 DU DU DU DU BRU DG DU 0.455782 0.883721
74 GKD 0.450382 0.91358
75 GFB 0.449612 0.890244
76 GDR 0.449612 0.890244
77 DC DG 0.449275 0.939024
78 UTP 0.446429 0.7875
79 6CK 0.446154 0.869048
80 KB7 0.445378 0.809524
81 YGP 0.445312 0.903614
82 44P 0.444444 0.759036
83 DG DG 0.444444 0.891566
84 U5F 0.442478 0.7875
85 Y9Z 0.44186 0.83908
86 GUD 0.441667 0.790123
87 660 0.441667 0.780488
88 URM 0.441667 0.780488
89 UFM 0.441667 0.790123
90 GDU 0.441667 0.790123
91 UTP U U U 0.441667 0.794872
92 UPG 0.441667 0.790123
93 G1R G1R 0.441379 0.902439
94 TPG 0.441379 0.824176
95 3UC 0.44 0.752941
96 GDX 0.43609 0.901235
97 G3A 0.435115 0.901235
98 UNP 0.434783 0.768293
99 C C 0.433333 0.871795
100 G5P 0.431818 0.901235
101 P2G 0.431034 0.839506
102 U2F 0.430894 0.752941
103 UPF 0.430894 0.752941
104 UFG 0.430894 0.752941
105 JB3 0.430657 0.879518
106 2KH 0.429825 0.768293
107 CAG 0.429577 0.840909
108 PGD O 0.428571 0.853933
109 GTG 0.427481 0.891566
110 Y6W 0.42623 0.752941
111 GPD 0.425373 0.858824
112 ZGP 0.42446 0.829545
113 P1G 0.423729 0.829268
114 UPA 0.423358 0.888889
115 DG DC 0.421769 0.903614
116 UDH 0.421488 0.735632
117 2MD 0.41844 0.872093
118 BGO 0.417266 0.857143
119 FEG 0.417266 0.83908
120 NGD 0.417266 0.91358
121 URI 0.415842 0.721519
122 USQ 0.412698 0.684783
123 KBD 0.410853 0.831325
124 UPP 0.409836 0.790123
125 GPX 0.409449 0.851852
126 G3N 0.409449 0.771084
127 UAD 0.408 0.768293
128 UDX 0.408 0.768293
129 UDM 0.407692 0.771084
130 UA3 0.407407 0.78481
131 U3P 0.407407 0.78481
132 EPZ 0.402878 0.771084
133 DGI 0.401639 0.833333
134 UD1 0.401515 0.780488
135 UD2 0.401515 0.780488
136 MGD 0.4 0.872093
137 EEB 0.4 0.761905
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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