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Receptor

PDB id	Resolution	Class	Description	Source	Keywords
6HYJ	1.93 Å	EC: 3.1.3.3	PSPH HUMAN PHOSPHOSERINE PHOSPHATASE	HOMO SAPIENS	PHOSPHOSERINE PHOSPHATASE HOMO SAPIENS HYDROLASE
Ref.:	CRYSTAL STRUCTURES AND SNAPSHOTS ALONG THE REACTION OF HUMAN PHOSPHOSERINE PHOSPHATASE. ACTA CRYSTALLOGR D STRUCT V. 75 592 2019 BIOL

Ligand

Ligand	Chain:Residue	Validity	Ligand Warnings	Binding Data	Molecular Weight (Da)	Formula	SMILES
CA	B:302; A:302;	Part of Protein; Part of Protein;	none; none;	submit data	40.078	Ca	[Ca+2...
SEP	B:301; A:301;	Valid; Valid;	none; none;	submit data	185.072	C3 H8 N O6 P	C([C@...
SER	B:303;	Valid;	none;	submit data	105.093	C3 H7 N O3	C([C@...

View in 3D viewer

90% Homology Family

Leader

PDB id	Resolution	Class	Description	Source	Keywords
6HYY	1.57 Å	EC: 3.1.3.3	HUMAN PHOSPHOSERINE PHOSPHATASE WITH SERINE AND PHOSPHATE	HOMO SAPIENS	HUMAN PHOSPHOSERINE PHOSPHATASE HYDROLASE
Ref.:	CRYSTAL STRUCTURES AND SNAPSHOTS ALONG THE REACTION OF HUMAN PHOSPHOSERINE PHOSPHATASE. ACTA CRYSTALLOGR D STRUCT V. 75 592 2019 BIOL

Members (2)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 5 families.
1	6HYJ	-	SEP	C3 H8 N O6 P	C([C@@H](C....
2	6HYY	-	SER	C3 H7 N O3	C([C@@H](C....

70% Homology Family (2)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 5 families.
1	6HYJ	-	SEP	C3 H8 N O6 P	C([C@@H](C....
2	6HYY	-	SER	C3 H7 N O3	C([C@@H](C....

50% Homology Family (2)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 5 families.
1	6HYJ	-	SEP	C3 H8 N O6 P	C([C@@H](C....
2	6HYY	-	SER	C3 H7 N O3	C([C@@H](C....

Polypharmacology

Similar Ligands (2D)

Ligand no: 1; Ligand: SEP; Similar ligands found: 15

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	SEP	1	1
2	3PG	0.515152	0.74359
3	4TP	0.513514	0.833333
4	GSE	0.512195	0.833333
5	DEZ	0.459459	0.707317
6	DER	0.459459	0.707317
7	DG2	0.459459	0.675
8	RGP	0.45	0.871795
9	PSE	0.428571	0.868421
10	PA5	0.425	0.707317
11	R10	0.425	0.707317
12	PGA	0.40625	0.710526
13	OSE	0.405405	0.733333
14	6PG	0.404762	0.707317
15	LG6	0.404762	0.707317

Ligand no: 2; Ligand: SER; Similar ligands found: 33

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	SER	1	1
2	DSN	1	1
3	DCY	0.65	0.84
4	CYS	0.65	0.84
5	DBB	0.6	0.692308
6	ABA	0.6	0.692308
7	2RA	0.6	0.75
8	HSE	0.590909	0.821429
9	C2N	0.571429	0.730769
10	ASN	0.545455	0.625
11	ASP	0.545455	0.714286
12	DAS	0.545455	0.714286
13	DAB	0.521739	0.724138
14	HL5	0.518519	0.814815
15	AS2	0.5	0.703704
16	NVA	0.5	0.62069
17	HCS	0.5	0.777778
18	CSO	0.5	0.636364
19	LEU	0.5	0.642857
20	API	0.5	0.633333
21	CSS	0.48	0.689655
22	DGY	0.47619	0.607143
23	DGL	0.461538	0.655172
24	GLU	0.461538	0.655172
25	GGL	0.461538	0.655172
26	ORN	0.444444	0.689655
27	SLZ	0.433333	0.625
28	DLY	0.413793	0.666667
29	11C	0.413793	0.633333
30	UN1	0.413793	0.633333
31	CME	0.40625	0.666667
32	LYS	0.4	0.645161
33	DHH	0.4	0.612903

Similar Ligands (3D)

Ligand no: 1; Ligand: SEP; Similar ligands found: 948

No:	Ligand	Similarity coefficient
1	13P	0.9910
2	G3P	0.9870
3	MSL	0.9834
4	HPV	0.9779
5	HG3	0.9727
6	LTL	0.9714
7	CYX	0.9655
8	OGA	0.9646
9	PEP	0.9633
10	AKG	0.9631
11	MHO	0.9588
12	G3H	0.9587
13	SYC	0.9583
14	GP9	0.9581
15	129	0.9575
16	B85	0.9573
17	SME	0.9567
18	HPS	0.9565
19	TPO	0.9555
20	9ON	0.9533
21	GLU	0.9519
22	PGH	0.9512
23	SPV	0.9498
24	GLN	0.9492
25	7OD	0.9488
26	HBU	0.9486
27	ONL	0.9482
28	PMF	0.9481
29	CHH	0.9480
30	2HG	0.9477
31	IP8	0.9463
32	Q03	0.9460
33	NM3	0.9460
34	SRT	0.9457
35	S2G	0.9450
36	2IT	0.9448
37	GGL	0.9447
38	CCD	0.9446
39	QMP	0.9438
40	AFS	0.9436
41	GVM	0.9436
42	3SL	0.9428
43	AT3	0.9418
44	4NG	0.9411
45	GPF	0.9408
46	GPJ	0.9408
47	CCE	0.9407
48	4LR	0.9386
49	3S5	0.9380
50	LYS	0.9379
51	1X4	0.9378
52	NM2	0.9377
53	LUQ	0.9374
54	PAB	0.9372
55	E4P	0.9368
56	URQ	0.9354
57	DGL	0.9353
58	PHB	0.9351
59	NPO	0.9349
60	GWM	0.9346
61	1GP	0.9342
62	G2H	0.9340
63	2PG	0.9340
64	ACH	0.9325
65	HIS	0.9321
66	PC	0.9321
67	1SA	0.9310
68	PPR	0.9310
69	3LR	0.9309
70	DGN	0.9294
71	DIR	0.9293
72	TAR	0.9286
73	O45	0.9276
74	AC6	0.9275
75	LFC	0.9275
76	PBZ	0.9274
77	LYN	0.9269
78	GZ3	0.9268
79	RTK	0.9262
80	2FT	0.9257
81	8U3	0.9254
82	TSU	0.9252
83	I4B	0.9252
84	NSB	0.9251
85	HBD	0.9251
86	AMS	0.9249
87	P22	0.9245
88	4SX	0.9245
89	FOM	0.9244
90	4NC	0.9242
91	Q02	0.9241
92	ZGL	0.9238
93	HGA	0.9236
94	ORN	0.9235
95	7C3	0.9234
96	GUA	0.9234
97	PAH	0.9234
98	SYM	0.9233
99	1Y6	0.9231
100	HHI	0.9225
101	DHI	0.9225
102	DHM	0.9224
103	MLT	0.9221
104	152	0.9218
105	KDG	0.9213
106	ASN	0.9212
107	TIH	0.9209
108	URP	0.9209
109	HMS	0.9206
110	DZA	0.9198
111	3AB	0.9197
112	3OC	0.9196
113	LX1	0.9196
114	1SH	0.9195
115	EKZ	0.9192
116	51R	0.9191
117	UN1	0.9190
118	Q9Z	0.9190
119	MES	0.9189
120	6JN	0.9188
121	PAC	0.9187
122	9GB	0.9185
123	OAA	0.9183
124	449	0.9182
125	8GL	0.9178
126	DS0	0.9175
127	P72	0.9171
128	0V5	0.9169
129	RAT	0.9167
130	E5X	0.9167
131	KMH	0.9166
132	DAL DAL	0.9166
133	BEN	0.9165
134	KPC	0.9164
135	PCA	0.9160
136	5XB	0.9156
137	PEQ	0.9155
138	FBW	0.9150
139	MEQ	0.9149
140	3HB	0.9149
141	MZT	0.9146
142	RNS	0.9146
143	NLE	0.9145
144	DYT	0.9144
145	173	0.9143
146	4HP	0.9142
147	PMB	0.9139
148	X0V	0.9136
149	MET	0.9135
150	AEG	0.9135
151	RUJ	0.9133
152	SAN	0.9131
153	ALA ALA	0.9129
154	RNT	0.9126
155	ASP	0.9122
156	4FH	0.9120
157	TLA	0.9116
158	9YT	0.9116
159	GAB	0.9115
160	4MA	0.9114
161	FOC	0.9113
162	DLY	0.9111
163	INO	0.9109
164	OOG	0.9109
165	2CO	0.9109
166	XIZ	0.9108
167	KVV	0.9107
168	0VT	0.9106
169	4P5	0.9106
170	LEU	0.9106
171	3FH	0.9105
172	HBA	0.9105
173	GLY GLY	0.9104
174	BHH	0.9103
175	AL0	0.9102
176	HSO	0.9102
177	QY9	0.9101
178	X1S	0.9099
179	AHB	0.9099
180	BEZ	0.9098
181	B40	0.9097
182	MAJ	0.9097
183	MAH	0.9094
184	FK8	0.9093
185	XM0	0.9093
186	OKG	0.9092
187	PO6	0.9091
188	3HG	0.9091
189	7A8	0.9091
190	IZC	0.9091
191	DOB	0.9089
192	PBC	0.9087
193	4P0	0.9086
194	4J8	0.9085
195	SOR	0.9084
196	BAM	0.9082
197	SIN	0.9080
198	FB2	0.9080
199	NIO	0.9079
200	8EW	0.9075
201	PZI	0.9072
202	OVV	0.9071
203	UNU	0.9070
204	CRN	0.9069
205	XCZ	0.9068
206	F9P	0.9067
207	SPA	0.9065
208	826	0.9065
209	NLP	0.9065
210	OEG	0.9064
211	XX2	0.9062
212	J0Z	0.9060
213	8OZ	0.9059
214	L14	0.9059
215	6NA	0.9057
216	TYE	0.9057
217	3QM	0.9056
218	3NT	0.9056
219	LMR	0.9055
220	HIO	0.9050
221	HL5	0.9048
222	P9P	0.9048
223	3PP	0.9047
224	TYL	0.9046
225	6PC	0.9046
226	5NU	0.9045
227	41K	0.9044
228	IXW	0.9044
229	HTX	0.9044
230	NCA	0.9044
231	HCI	0.9042
232	AMH	0.9042
233	K7M	0.9040
234	PHU	0.9040
235	KVP	0.9040
236	M4T	0.9040
237	CFI	0.9040
238	REL	0.9039
239	93K	0.9038
240	IFP	0.9038
241	URO	0.9035
242	LLQ	0.9035
243	NBZ	0.9035
244	MYJ	0.9034
245	TCA	0.9034
246	Z82	0.9032
247	FCR	0.9032
248	DAV	0.9032
249	GLO	0.9031
250	SOL	0.9030
251	PHE	0.9030
252	MUC	0.9030
253	ISZ	0.9029
254	XSP	0.9029
255	3HP	0.9028
256	SW7	0.9027
257	R9S	0.9027
258	HHA	0.9027
259	UFV	0.9027
260	3F0	0.9027
261	COI	0.9025
262	HSX	0.9025
263	GRO	0.9024
264	RP3	0.9023
265	4NM	0.9023
266	RSO	0.9022
267	2JJ	0.9021
268	HF2	0.9021
269	2HO	0.9020
270	DHY	0.9019
271	SG3	0.9018
272	3PF	0.9017
273	4CS	0.9015
274	QSB	0.9015
275	PNZ	0.9015
276	HIC	0.9013
277	R67	0.9011
278	7UC	0.9011
279	DHB	0.9011
280	9TW	0.9011
281	MSE	0.9010
282	SS1	0.9009
283	1P3	0.9009
284	DAR	0.9009
285	KTA	0.9008
286	258	0.9007
287	9RW	0.9007
288	TPA	0.9007
289	PZA	0.9007
290	7BC	0.9006
291	TEO	0.9005
292	BNF	0.9005
293	CHB	0.9003
294	HFA	0.9001
295	IHB	0.9001
296	DBH	0.8998
297	BHO	0.8998
298	9J3	0.8998
299	I38	0.8995
300	6NT	0.8995
301	M45	0.8993
302	MTL	0.8992
303	FA0	0.8991
304	CXP	0.8991
305	3YP	0.8991
306	MT2	0.8990
307	DPN	0.8990
308	5CU	0.8990
309	MED	0.8990
310	FBV	0.8990
311	3HA	0.8990
312	PPY	0.8987
313	BHU	0.8987
314	KPA	0.8986
315	K6V	0.8986
316	RMN	0.8986
317	SD4	0.8985
318	0L1	0.8985
319	URS	0.8984
320	268	0.8984
321	B3U	0.8982
322	9RH	0.8981
323	SMN	0.8980
324	LY0	0.8980
325	PLU	0.8980
326	6M4	0.8979
327	XXG	0.8979
328	FUD	0.8979
329	H95	0.8977
330	BHA	0.8977
331	DXP	0.8974
332	UY7	0.8974
333	BE2	0.8974
334	KMT	0.8973
335	F98	0.8972
336	NFA	0.8972
337	AOS	0.8972
338	2AS	0.8970
339	OTR	0.8970
340	4FA	0.8970
341	49F	0.8970
342	BPN	0.8969
343	RBL	0.8968
344	MLE	0.8966
345	2BX	0.8966
346	6FZ	0.8965
347	ARG	0.8965
348	OHP	0.8964
349	40E	0.8963
350	3NY	0.8962
351	K34	0.8962
352	XLS	0.8962
353	7N0	0.8961
354	ASC	0.8961
355	C5A	0.8960
356	GLL	0.8960
357	PIM	0.8959
358	SHI	0.8959
359	4MV	0.8958
360	ANN	0.8958
361	J9T	0.8958
362	ACA	0.8956
363	S7A	0.8956
364	GJZ	0.8955
365	DHS	0.8955
366	YRL	0.8954
367	MPH	0.8953
368	9X6	0.8952
369	NIZ	0.8952
370	3M0	0.8952
371	4VP	0.8951
372	D5X	0.8951
373	N6C	0.8951
374	36E	0.8949
375	53C	0.8948
376	MDN	0.8943
377	FBS	0.8943
378	BL0	0.8942
379	ROR	0.8941
380	174	0.8941
381	AG2	0.8940
382	THE	0.8939
383	A13	0.8939
384	AHN	0.8937
385	4BZ	0.8937
386	1DV	0.8937
387	MRZ	0.8936
388	M58	0.8935
389	4M0	0.8934
390	R20	0.8933
391	ABF	0.8930
392	R2P	0.8930
393	DXG	0.8928
394	8K2	0.8928
395	J9N	0.8927
396	2O6	0.8926
397	FA1	0.8926
398	ZXD	0.8925
399	QSC	0.8925
400	717	0.8924
401	3C4	0.8924
402	S2P	0.8924
403	R9M	0.8924
404	SAL	0.8923
405	AHR	0.8923
406	FIX	0.8922
407	JAW	0.8922
408	7WG	0.8921
409	98J	0.8921
410	SHV	0.8920
411	4WL	0.8920
412	IOM	0.8917
413	HDL	0.8916
414	EVF	0.8916
415	KOJ	0.8916
416	AOT	0.8912
417	650	0.8912
418	3BZ	0.8911
419	NMJ	0.8910
420	VKC	0.8909
421	HDA	0.8909
422	EDR	0.8907
423	FUM	0.8906
424	NTN	0.8905
425	2PN	0.8905
426	5FX	0.8904
427	BCU	0.8904
428	ILO	0.8904
429	4JL	0.8903
430	BTM	0.8903
431	AZM	0.8903
432	ENV	0.8903
433	SDF	0.8903
434	QDK	0.8902
435	HDH	0.8902
436	HX2	0.8902
437	MSR	0.8901
438	SKM	0.8900
439	4ZA	0.8900
440	AEF	0.8900
441	P7Y	0.8898
442	3U4	0.8898
443	069	0.8898
444	NCT	0.8897
445	FAN	0.8897
446	CXF	0.8897
447	MD0	0.8897
448	MPJ	0.8896
449	VGL	0.8896
450	L5V	0.8895
451	JZ7	0.8895
452	5WZ	0.8895
453	92K	0.8895
454	9SE	0.8895
455	HY1	0.8894
456	FF3	0.8893
457	YCP	0.8893
458	BZ3	0.8893
459	TIU	0.8892
460	FB1	0.8891
461	11C	0.8891
462	MJ2	0.8889
463	NNO	0.8888
464	BNS	0.8888
465	DAS	0.8888
466	2ZM	0.8888
467	A09	0.8887
468	CCU	0.8886
469	3V4	0.8884
470	8SZ	0.8882
471	IT2	0.8882
472	ITN	0.8882
473	K6H	0.8881
474	RHU	0.8880
475	2RH	0.8879
476	XYH	0.8878
477	PRA	0.8877
478	ESP	0.8877
479	G8M	0.8877
480	AC0	0.8875
481	H42	0.8875
482	IFL	0.8875
483	BNL	0.8875
484	5OB	0.8874
485	IPB	0.8874
486	4A3	0.8873
487	3BU	0.8872
488	CS2	0.8871
489	0OC	0.8870
490	FBA	0.8870
491	4AA	0.8869
492	23J	0.8869
493	YOF	0.8868
494	APG	0.8868
495	PEA	0.8868
496	XYL	0.8867
497	GCO	0.8865
498	FHB	0.8865
499	A29	0.8865
500	SKJ	0.8865
501	L99	0.8864
502	JB8	0.8864
503	0HN	0.8863
504	ES6	0.8863
505	DLT	0.8862
506	4LV	0.8862
507	P80	0.8861
508	SHF	0.8861
509	HYA	0.8860
510	UYA	0.8860
511	EOU	0.8860
512	GLC	0.8859
513	8GC	0.8859
514	8WO	0.8859
515	DAH	0.8858
516	MNM	0.8858
517	DYA	0.8855
518	1F1	0.8855
519	5HY	0.8853
520	UA5	0.8853
521	TAG	0.8852
522	271	0.8850
523	MEV	0.8849
524	JYD	0.8849
525	CMS	0.8849
526	CPZ	0.8849
527	DHK	0.8847
528	88L	0.8847
529	3MV	0.8846
530	BZ2	0.8846
531	EHM	0.8844
532	P58	0.8844
533	K5W	0.8844
534	IFM	0.8843
535	FQI	0.8843
536	4TB	0.8842
537	N4B	0.8842
538	SKG	0.8842
539	6NI	0.8841
540	FBM	0.8840
541	ONH	0.8839
542	LLH	0.8837
543	HC4	0.8837
544	PPV	0.8837
545	LPK	0.8837
546	OK7	0.8835
547	POP	0.8834
548	PEL	0.8834
549	N9J	0.8834
550	ADA	0.8833
551	2D8	0.8832
552	AAS	0.8831
553	SVD	0.8831
554	2AL	0.8831
555	DCO	0.8830
556	61M	0.8829
557	ABI	0.8828
558	M4S	0.8827
559	OMD	0.8827
560	5QY	0.8826
561	ICF	0.8825
562	IVL	0.8825
563	CIZ	0.8825
564	IWT	0.8824
565	HQJ	0.8824
566	ICB	0.8824
567	NF3	0.8823
568	EN1	0.8822
569	CIR	0.8822
570	HHH	0.8821
571	JDN	0.8821
572	NOJ	0.8819
573	SWA	0.8819
574	BZX	0.8819
575	NYL	0.8819
576	0HO	0.8818
577	LNO	0.8817
578	4JM	0.8817
579	MZB	0.8817
580	FPI	0.8815
581	PSJ	0.8814
582	RB5	0.8813
583	97T	0.8813
584	GDE	0.8813
585	JKE	0.8812
586	JLZ	0.8812
587	PBA	0.8812
588	TYR	0.8811
589	DTY	0.8811
590	BE7	0.8811
591	4JT	0.8811
592	MNN	0.8811
593	SJ5	0.8810
594	36Y	0.8810
595	S24	0.8809
596	BRH	0.8809
597	259	0.8809
598	S8V	0.8808
599	RBJ	0.8808
600	PIY	0.8808
601	G2F	0.8807
602	52C	0.8807
603	5XA	0.8807
604	M74	0.8807
605	GYE	0.8806
606	ISA	0.8806
607	PIS	0.8805
608	CTS	0.8804
609	5QX	0.8804
610	3A9	0.8804
611	UGC	0.8803
612	1L5	0.8802
613	HX4	0.8802
614	HSE	0.8801
615	4XR	0.8801
616	DA4	0.8801
617	M3H	0.8799
618	A3M	0.8799
619	QUS	0.8797
620	BSX	0.8797
621	911	0.8797
622	DGJ	0.8796
623	3HM	0.8796
624	TZL	0.8796
625	MXN	0.8795
626	FHC	0.8794
627	1FD	0.8793
628	CN0	0.8793
629	5NI	0.8793
630	ASO	0.8791
631	3AL	0.8791
632	5RP	0.8790
633	XUL	0.8789
634	HMH	0.8789
635	4JC	0.8787
636	GZL	0.8786
637	Q06	0.8786
638	SS2	0.8785
639	SNE	0.8785
640	PRO GLY	0.8783
641	DBX	0.8783
642	HJH	0.8782
643	54D	0.8781
644	IAC	0.8780
645	LNR	0.8779
646	2CK	0.8778
647	ARW	0.8776
648	A5E	0.8776
649	VAH	0.8775
650	KBB	0.8774
651	TTL	0.8773
652	DE5	0.8773
653	BDP	0.8772
654	ENO	0.8771
655	IOS	0.8771
656	6TZ	0.8771
657	4PN	0.8770
658	1BN	0.8770
659	8EZ	0.8769
660	M6H	0.8768
661	PZM	0.8766
662	QIC	0.8766
663	4LW	0.8765
664	HZP	0.8765
665	HPP	0.8764
666	ILE	0.8763
667	SN4	0.8760
668	GLA	0.8760
669	HMU	0.8759
670	AMC	0.8759
671	ESX	0.8758
672	S0E	0.8758
673	RNO	0.8758
674	4XS	0.8757
675	2HU	0.8757
676	Q04	0.8757
677	LT2	0.8755
678	EXD	0.8755
679	XXP	0.8754
680	ABV	0.8754
681	C2B	0.8753
682	263	0.8752
683	TH7	0.8751
684	RP5	0.8750
685	GIF	0.8750
686	LCN	0.8749
687	1DJ	0.8749
688	FEH	0.8749
689	LDP	0.8748
690	3PO	0.8748
691	2HC	0.8748
692	FYU	0.8748
693	1PT	0.8746
694	GVG	0.8746
695	JB5	0.8746
696	HNL	0.8746
697	PPT	0.8745
698	CTL	0.8743
699	3ID	0.8743
700	HL4	0.8742
701	AX7	0.8741
702	SNU	0.8738
703	LDU	0.8737
704	6OT	0.8737
705	XBT	0.8737
706	PJL	0.8736
707	RIB	0.8736
708	4YO	0.8736
709	IF7	0.8735
710	NDH	0.8735
711	5H1	0.8735
712	HQ9	0.8735
713	15N	0.8734
714	ES5	0.8734
715	14O	0.8733
716	03V	0.8732
717	FBU	0.8732
718	0JD	0.8732
719	7VP	0.8729
720	EYK	0.8729
721	AHC	0.8727
722	COU	0.8727
723	F60	0.8727
724	GAL	0.8726
725	TZE	0.8726
726	J9Q	0.8726
727	0CG	0.8726
728	AMQ	0.8725
729	X1P	0.8725
730	NSP	0.8724
731	IPM	0.8724
732	F4E	0.8722
733	ET2	0.8722
734	GBN	0.8721
735	IYR	0.8721
736	2AQ	0.8720
737	2MI	0.8720
738	AGK	0.8719
739	1WD	0.8719
740	5MI	0.8719
741	2K4	0.8719
742	MPV	0.8718
743	GOJ	0.8717
744	P9E	0.8717
745	I1E	0.8716
746	MWP	0.8715
747	HNK	0.8715
748	4FS	0.8715
749	TEG	0.8714
750	OCH	0.8713
751	PH3	0.8713
752	LR5	0.8713
753	PRO	0.8713
754	4NZ	0.8712
755	MAE	0.8712
756	JF6	0.8712
757	CLT	0.8712
758	270	0.8711
759	DQY	0.8711
760	DMD	0.8710
761	6DP	0.8710
762	XX3	0.8710
763	SHA	0.8708
764	RUY	0.8707
765	CXH	0.8707
766	7MK	0.8706
767	GRF	0.8706
768	6AI	0.8706
769	OPE	0.8706
770	ABN	0.8705
771	4XV	0.8705
772	VNJ	0.8704
773	PDC	0.8704
774	8H8	0.8704
775	T9G	0.8704
776	CFA	0.8703
777	WCE	0.8702
778	PD2	0.8702
779	ISD	0.8702
780	DII	0.8702
781	505	0.8701
782	C1M	0.8701
783	PRY	0.8699
784	GTK	0.8699
785	XIY	0.8698
786	ODO	0.8698
787	Q07	0.8697
788	5MB	0.8697
789	H62	0.8697
790	3CR	0.8694
791	2LP	0.8694
792	DHC	0.8692
793	DMJ	0.8689
794	NHG	0.8687
795	JVN	0.8685
796	33S	0.8685
797	15E	0.8684
798	2CL	0.8684
799	NVA	0.8684
800	KJH	0.8684
801	CIT	0.8683
802	STT	0.8683
803	E79	0.8683
804	MR1	0.8683
805	NXA	0.8683
806	SYV	0.8682
807	51F	0.8682
808	1LN	0.8682
809	Z13	0.8682
810	NPY	0.8680
811	TSR	0.8678
812	6M9	0.8677
813	0A9	0.8677
814	4NB	0.8676
815	1P8	0.8676
816	QUZ	0.8675
817	ES2	0.8675
818	CEE	0.8674
819	B3M	0.8673
820	2TQ	0.8673
821	TZF	0.8673
822	TZM	0.8672
823	R1P	0.8672
824	ZBT	0.8671
825	JZ4	0.8670
826	2BG	0.8670
827	SYN	0.8670
828	7WV	0.8668
829	3AE	0.8667
830	FBB	0.8667
831	2C2	0.8667
832	CLW	0.8665
833	4JQ	0.8665
834	YZM	0.8664
835	HSM	0.8664
836	MZW	0.8662
837	L22	0.8661
838	NOY	0.8661
839	R2B	0.8661
840	11S	0.8661
841	G3E	0.8660
842	QSH	0.8660
843	9R5	0.8659
844	FLC	0.8659
845	M44	0.8658
846	1A7	0.8657
847	AVI	0.8657
848	PAF	0.8655
849	IDM	0.8655
850	1M2	0.8655
851	DHR	0.8654
852	HCS	0.8653
853	HBX	0.8653
854	K2T	0.8652
855	VGD	0.8651
856	GCU	0.8651
857	FBF	0.8651
858	24B	0.8650
859	H8N	0.8650
860	XQ0	0.8650
861	5WV	0.8649
862	36R	0.8648
863	FP1	0.8648
864	MP5	0.8647
865	56D	0.8647
866	9FE	0.8645
867	4SV	0.8644
868	6RQ	0.8643
869	ES9	0.8643
870	2F6	0.8642
871	GAF	0.8642
872	Y4L	0.8641
873	12Q	0.8641
874	ZZT	0.8640
875	SOE	0.8639
876	DEW	0.8638
877	G4D	0.8636
878	PEZ	0.8636
879	KKN	0.8635
880	X6X	0.8635
881	GXL	0.8634
882	FBJ	0.8634
883	JZ5	0.8634
884	5GU	0.8633
885	D48	0.8632
886	67N	0.8630
887	XDK	0.8629
888	KYN	0.8629
889	MS9	0.8628
890	TB6	0.8627
891	BPW	0.8627
892	NK2	0.8626
893	XRX	0.8624
894	5XC	0.8623
895	GZ2	0.8614
896	ES7	0.8614
897	264	0.8611
898	SR1	0.8611
899	54Z	0.8610
900	P81	0.8608
901	KDF	0.8608
902	L3Q	0.8607
903	42J	0.8606
904	261	0.8605
905	KPL	0.8603
906	PRZ	0.8601
907	RLG	0.8601
908	5HN	0.8600
909	40F	0.8597
910	YPN	0.8595
911	0BP	0.8595
912	AZF	0.8594
913	BVA	0.8594
914	WOT	0.8590
915	7Q1	0.8587
916	4V2	0.8586
917	X8Z	0.8586
918	N2Z	0.8584
919	4XF	0.8584
920	ISN	0.8580
921	JRB	0.8580
922	PPK	0.8579
923	GLF	0.8578
924	C21	0.8578
925	S7J	0.8576
926	12T	0.8574
927	1DU	0.8571
928	7QS	0.8569
929	60P	0.8568
930	EUE	0.8567
931	I2M	0.8566
932	4VY	0.8565
933	LYL	0.8560
934	RUU	0.8560
935	RES	0.8560
936	M1A	0.8559
937	SC2	0.8558
938	KBZ	0.8556
939	NVU	0.8553
940	1Z6	0.8545
941	BRT	0.8542
942	1WC	0.8541
943	69O	0.8532
944	PYF	0.8530
945	RM1	0.8527
946	S0H	0.8526
947	DDK	0.8526
948	PXL	0.8507

Ligand no: 2; Ligand: SER; Similar ligands found: 667

No:	Ligand	Similarity coefficient
1	DE2	1.0000
2	3PY	1.0000
3	TAR	1.0000
4	SMB	1.0000
5	HUI	1.0000
6	DXX	1.0000
7	39J	0.9987
8	2KT	0.9984
9	KG7	0.9971
10	1AC	0.9864
11	ALA	0.9831
12	THR	0.9831
13	LAC	0.9792
14	2OP	0.9775
15	03W	0.9773
16	HIU	0.9773
17	OXL	0.9770
18	A3B	0.9766
19	PYR	0.9754
20	MB3	0.9746
21	ALQ	0.9719
22	HBS	0.9705
23	SSN	0.9680
24	NIS	0.9669
25	VAL	0.9668
26	CAQ	0.9666
27	9YL	0.9662
28	OXM	0.9658
29	CEJ	0.9658
30	23W	0.9655
31	OXD	0.9655
32	HV2	0.9653
33	MLI	0.9641
34	9X7	0.9640
35	2HA	0.9633
36	LER	0.9628
37	MLA	0.9622
38	GOL	0.9620
39	GXV	0.9620
40	192	0.9617
41	E60	0.9616
42	HGY	0.9607
43	C5J	0.9606
44	3GR	0.9606
45	NAK	0.9601
46	IPH	0.9599
47	ALO	0.9596
48	HBR	0.9594
49	AKB	0.9593
50	DTL	0.9582
51	TF4	0.9582
52	BAL	0.9573
53	IQ0	0.9573
54	PPF	0.9561
55	273	0.9559
56	MMZ	0.9554
57	MEU	0.9552
58	PYM	0.9552
59	3OH	0.9551
60	TAY	0.9550
61	AOA	0.9542
62	TFB	0.9541
63	DAL	0.9540
64	BUQ	0.9538
65	PRS	0.9537
66	BUB	0.9537
67	2PC	0.9536
68	PRO	0.9536
69	BUO	0.9536
70	MRY	0.9535
71	KIV	0.9534
72	DMG	0.9533
73	BAQ	0.9531
74	SAR	0.9530
75	FW5	0.9526
76	AAE	0.9522
77	7EX	0.9519
78	KSW	0.9515
79	2IM	0.9514
80	BU4	0.9509
81	5Y9	0.9508
82	BMD	0.9504
83	40O	0.9503
84	BUA	0.9499
85	69O	0.9495
86	MAK	0.9494
87	CYH	0.9494
88	LEA	0.9492
89	CXL	0.9492
90	BAE	0.9490
91	MLM	0.9487
92	A2Q	0.9483
93	280	0.9478
94	ICN	0.9475
95	HYN	0.9471
96	3ZQ	0.9469
97	NVI	0.9464
98	BXO	0.9462
99	CHT	0.9459
100	XIX	0.9458
101	V1L	0.9451
102	4AX	0.9449
103	HDA	0.9443
104	MZ0	0.9442
105	DTI	0.9442
106	HRZ	0.9441
107	9PO	0.9440
108	3HL	0.9435
109	1SP	0.9434
110	LGA	0.9434
111	3HR	0.9432
112	DMI	0.9428
113	2AP	0.9427
114	HVK	0.9427
115	XAP	0.9427
116	IVA	0.9426
117	DCD	0.9426
118	3AP	0.9425
119	HAI	0.9424
120	MBN	0.9423
121	HSL	0.9422
122	GXE	0.9421
123	4AP	0.9420
124	HPY	0.9414
125	MTG	0.9411
126	BEW	0.9410
127	24T	0.9409
128	ATQ	0.9406
129	P2D	0.9405
130	ABU	0.9404
131	AMT	0.9404
132	GBL	0.9402
133	URA	0.9401
134	WOT	0.9400
135	MAE	0.9399
136	MMU	0.9396
137	T2C	0.9394
138	HZP	0.9393
139	DTT	0.9391
140	3TR	0.9387
141	8CL	0.9387
142	PRI	0.9384
143	TMT	0.9384
144	93B	0.9383
145	278	0.9380
146	ODV	0.9374
147	6SP	0.9371
148	L60	0.9368
149	HVQ	0.9368
150	SIN	0.9366
151	8X3	0.9363
152	25T	0.9362
153	FUM	0.9358
154	J1Z	0.9356
155	26D	0.9352
156	BVG	0.9351
157	ITU	0.9350
158	1DU	0.9348
159	CRS	0.9346
160	1CB	0.9344
161	3BB	0.9342
162	265	0.9339
163	3MT	0.9336
164	TP5	0.9336
165	A8C	0.9333
166	SLP	0.9331
167	TTO	0.9328
168	9TY	0.9327
169	HGQ	0.9323
170	DTU	0.9321
171	XPO	0.9321
172	IHG	0.9321
173	HBX	0.9319
174	TAU	0.9318
175	PYC	0.9318
176	FOA	0.9317
177	VX	0.9316
178	BVC	0.9313
179	MR3	0.9312
180	HOW	0.9311
181	2HE	0.9309
182	POA	0.9309
183	C21	0.9308
184	282	0.9304
185	WTZ	0.9303
186	2MZ	0.9303
187	SYN	0.9303
188	PYF	0.9301
189	1MZ	0.9300
190	H3M	0.9300
191	2AI	0.9298
192	JZ6	0.9297
193	SGL	0.9296
194	D2P	0.9293
195	MZY	0.9292
196	TMZ	0.9292
197	4HA	0.9291
198	EGD	0.9291
199	NXA	0.9288
200	2EZ	0.9285
201	5MP	0.9285
202	5KX	0.9285
203	4MZ	0.9284
204	1DH	0.9278
205	ETX	0.9277
206	CYT	0.9276
207	RCO	0.9276
208	GOA	0.9270
209	PUT	0.9267
210	NBE	0.9266
211	285	0.9266
212	HHN	0.9265
213	TZC	0.9265
214	DUC	0.9264
215	PE9	0.9263
216	23B	0.9263
217	PYG	0.9262
218	SMV	0.9261
219	4JU	0.9259
220	IDH	0.9259
221	ABN	0.9258
222	LDU	0.9257
223	4CH	0.9256
224	PY7	0.9253
225	JZ3	0.9250
226	LG3	0.9250
227	QFH	0.9250
228	HLT	0.9248
229	BVF	0.9245
230	HYP	0.9245
231	4XX	0.9242
232	3CH	0.9240
233	ECE	0.9239
234	WBU	0.9237
235	BYZ	0.9235
236	NMG	0.9234
237	DPR	0.9231
238	93Q	0.9230
239	APY	0.9230
240	B20	0.9225
241	PIH	0.9223
242	MLT	0.9222
243	TEO	0.9222
244	OXE	0.9219
245	FJO	0.9219
246	2DR	0.9219
247	URF	0.9217
248	PPI	0.9216
249	LG5	0.9215
250	HQE	0.9214
251	FP2	0.9213
252	BTL	0.9212
253	YAN	0.9211
254	GLY	0.9211
255	NK	0.9210
256	FAH	0.9209
257	THE	0.9209
258	JAB	0.9208
259	92Z	0.9207
260	4MV	0.9207
261	F3V	0.9205
262	8GF	0.9204
263	AC5	0.9203
264	PLQ	0.9201
265	CIG	0.9200
266	284	0.9200
267	L89	0.9199
268	1MR	0.9198
269	EDG	0.9198
270	4DX	0.9198
271	AMC	0.9197
272	4HO	0.9197
273	TDR	0.9195
274	1AB	0.9194
275	2AF	0.9194
276	JZ0	0.9193
277	3SS	0.9191
278	DA1	0.9189
279	ICC	0.9189
280	BNZ	0.9188
281	76X	0.9187
282	ITN	0.9186
283	ILE	0.9183
284	R8A	0.9182
285	HGW	0.9182
286	PHZ	0.9182
287	2A1	0.9181
288	HX2	0.9180
289	FPN	0.9178
290	HEW	0.9178
291	HTS	0.9178
292	2CH	0.9177
293	IOM	0.9176
294	UGC	0.9176
295	0PY	0.9175
296	1AN	0.9175
297	FMS	0.9174
298	LG4	0.9174
299	PYJ	0.9173
300	TH0	0.9173
301	RP7	0.9173
302	8LG	0.9170
303	3ZS	0.9169
304	4H2	0.9167
305	TB6	0.9167
306	R2B	0.9167
307	40E	0.9166
308	FPI	0.9166
309	PCR	0.9165
310	JBN	0.9164
311	ETM	0.9161
312	MCT	0.9161
313	ES3	0.9160
314	FLA	0.9158
315	AML	0.9157
316	25R	0.9157
317	HAE	0.9155
318	6X8	0.9153
319	5MH	0.9153
320	FCN	0.9152
321	2A3	0.9152
322	938	0.9152
323	GLV	0.9152
324	B3R	0.9151
325	OAA	0.9150
326	BRP	0.9149
327	XBZ	0.9149
328	CP	0.9147
329	PXY	0.9147
330	2MH	0.9147
331	CMS	0.9146
332	275	0.9145
333	JZ2	0.9144
334	PYZ	0.9143
335	HY3	0.9142
336	LMR	0.9140
337	P1R	0.9137
338	HSW	0.9137
339	4CL	0.9136
340	2AC	0.9136
341	DCL	0.9135
342	GAG	0.9134
343	0R0	0.9132
344	B24	0.9131
345	4ZE	0.9130
346	1MC	0.9129
347	CNH	0.9129
348	BR9	0.9127
349	HHQ	0.9126
350	NIE	0.9126
351	MWM	0.9125
352	M3T	0.9125
353	H95	0.9123
354	XYD	0.9123
355	4HS	0.9121
356	4JJ	0.9120
357	VAH	0.9117
358	HSM	0.9116
359	6UA	0.9116
360	TSZ	0.9114
361	NEQ	0.9113
362	27Y	0.9112
363	A1U	0.9111
364	286	0.9111
365	ETF	0.9110
366	SAT	0.9109
367	2MP	0.9108
368	61G	0.9106
369	34A	0.9105
370	R1X	0.9103
371	YCP	0.9102
372	PYD	0.9102
373	ICP	0.9102
374	BML	0.9102
375	RSF	0.9101
376	4JN	0.9096
377	NCM	0.9094
378	AGU	0.9093
379	JZ5	0.9091
380	J3K	0.9087
381	IPU	0.9087
382	9CL	0.9082
383	BP9	0.9082
384	2YU	0.9081
385	13D	0.9078
386	MWJ	0.9077
387	DZZ	0.9076
388	3MC	0.9076
389	CRN	0.9074
390	98J	0.9073
391	MTD	0.9071
392	IMR	0.9070
393	PAE	0.9067
394	PCA	0.9066
395	AKR	0.9062
396	PXO	0.9060
397	5UC	0.9058
398	5AC	0.9055
399	TFS	0.9051
400	YHO	0.9051
401	43M	0.9049
402	OXQ	0.9048
403	P7I	0.9047
404	3CL	0.9046
405	F50	0.9045
406	MSF	0.9045
407	COM	0.9043
408	3FA	0.9041
409	60P	0.9040
410	MPI	0.9039
411	JZ9	0.9036
412	NBZ	0.9035
413	HT4	0.9031
414	51F	0.9031
415	2CO	0.9029
416	CRD	0.9028
417	MBD	0.9028
418	FPY	0.9027
419	5JC	0.9027
420	FFP	0.9026
421	QOS	0.9025
422	ISU	0.9020
423	JZ1	0.9020
424	OHG	0.9020
425	CP2	0.9018
426	CIZ	0.9018
427	BZI	0.9018
428	4JO	0.9018
429	R3W	0.9017
430	HVB	0.9014
431	GBD	0.9014
432	0R1	0.9014
433	2CM	0.9011
434	6NA	0.9010
435	MGX	0.9008
436	TM7	0.9008
437	AX2	0.9008
438	GVH	0.9006
439	3CE	0.9005
440	VSO	0.9004
441	47J	0.9003
442	DEN	0.9002
443	2C9	0.9001
444	FLM	0.9001
445	IOL	0.9001
446	MRZ	0.9001
447	0CT	0.9000
448	BEZ	0.8998
449	GMN	0.8997
450	IUR	0.8997
451	BZF	0.8996
452	3MH	0.8995
453	14J	0.8995
454	TAN	0.8994
455	2MY	0.8994
456	9A4	0.8993
457	IND	0.8991
458	NHY	0.8988
459	EFS	0.8984
460	GG6	0.8984
461	1XX	0.8982
462	LZ1	0.8982
463	MPD	0.8978
464	NMU	0.8974
465	TM4	0.8972
466	TZZ	0.8971
467	PZA	0.8967
468	TB0	0.8963
469	IDM	0.8963
470	JZ7	0.8963
471	6MH	0.8962
472	3SY	0.8959
473	1PT	0.8958
474	1DQ	0.8957
475	2ZX	0.8955
476	NIO	0.8954
477	BAM	0.8953
478	MET	0.8949
479	6PC	0.8948
480	3AY	0.8946
481	4SD	0.8944
482	MZW	0.8944
483	WDL	0.8943
484	IT2	0.8941
485	H76	0.8938
486	DUB	0.8935
487	COI	0.8934
488	TZL	0.8934
489	ZBT	0.8934
490	NCA	0.8934
491	Z6J	0.8932
492	5ZE	0.8925
493	XYS	0.8922
494	13X	0.8921
495	PG3	0.8915
496	OPE	0.8915
497	UY7	0.8914
498	XBT	0.8910
499	MZG	0.8910
500	ALF	0.8910
501	BEN	0.8909
502	DYA	0.8907
503	XYP	0.8906
504	ATO	0.8902
505	TCV	0.8902
506	4JP	0.8901
507	VGL	0.8900
508	Y8I	0.8899
509	FUB	0.8899
510	2RH	0.8895
511	DSS	0.8892
512	TLD	0.8889
513	ADE	0.8887
514	O7U	0.8877
515	XLS	0.8875
516	PGA	0.8874
517	9SB	0.8873
518	JYD	0.8869
519	M6W	0.8869
520	M2H	0.8866
521	HBA	0.8866
522	XUL	0.8864
523	8FH	0.8863
524	S0H	0.8861
525	FQI	0.8860
526	PAV	0.8858
527	ROR	0.8857
528	UYA	0.8857
529	32O	0.8856
530	PCT	0.8854
531	AHR	0.8854
532	BR8	0.8853
533	BXA	0.8849
534	TZE	0.8849
535	7VD	0.8845
536	ERH	0.8844
537	BDR	0.8840
538	54D	0.8838
539	9X6	0.8838
540	MMQ	0.8835
541	1BP	0.8835
542	3XX	0.8831
543	UNU	0.8831
544	2XX	0.8827
545	NTN	0.8819
546	5AN	0.8819
547	KYD	0.8817
548	AC0	0.8816
549	7HP	0.8811
550	TMH	0.8809
551	SS1	0.8809
552	34V	0.8808
553	MSE	0.8806
554	4JL	0.8804
555	BZX	0.8804
556	6AI	0.8795
557	C2A	0.8792
558	RIB	0.8792
559	2K4	0.8789
560	7CZ	0.8787
561	M58	0.8787
562	OXZ	0.8786
563	4VP	0.8786
564	SAL	0.8783
565	TLA	0.8783
566	11S	0.8780
567	0TR	0.8779
568	T6C	0.8779
569	5H1	0.8778
570	7MH	0.8775
571	0MK	0.8774
572	14O	0.8772
573	RUU	0.8771
574	QSC	0.8770
575	ES9	0.8770
576	5MB	0.8770
577	5MI	0.8769
578	KMT	0.8767
579	PAF	0.8764
580	DMV	0.8763
581	FBA	0.8763
582	94N	0.8762
583	RIP	0.8762
584	FYU	0.8761
585	6HQ	0.8761
586	SEJ	0.8757
587	PBC	0.8756
588	HPA	0.8755
589	JIF	0.8753
590	PEP	0.8751
591	PBE	0.8750
592	OEM	0.8746
593	KPL	0.8743
594	4XR	0.8740
595	F60	0.8737
596	FK1	0.8736
597	BTE	0.8730
598	KOJ	0.8721
599	BE2	0.8720
600	IP0	0.8717
601	HY1	0.8716
602	RSO	0.8715
603	VNJ	0.8711
604	4SV	0.8710
605	SS2	0.8709
606	IFM	0.8706
607	DFB	0.8706
608	AZF	0.8703
609	SRT	0.8700
610	URP	0.8700
611	2AS	0.8694
612	7WG	0.8689
613	FAN	0.8687
614	3U4	0.8686
615	9A7	0.8685
616	64K	0.8684
617	ABE	0.8684
618	1LN	0.8683
619	ES6	0.8683
620	H8N	0.8681
621	YTB	0.8680
622	271	0.8678
623	HIO	0.8677
624	ARA	0.8675
625	HMH	0.8674
626	BNS	0.8674
627	3SK	0.8673
628	FP1	0.8672
629	9EW	0.8669
630	SNE	0.8667
631	FUC	0.8658
632	ZZT	0.8656
633	TH7	0.8652
634	8EZ	0.8651
635	C2B	0.8651
636	ICF	0.8645
637	F05	0.8641
638	1DV	0.8633
639	L3Q	0.8632
640	1WD	0.8630
641	FUL	0.8628
642	261	0.8626
643	FPK	0.8625
644	MED	0.8623
645	HX3	0.8621
646	PHB	0.8620
647	OK7	0.8620
648	JKE	0.8619
649	XRG	0.8617
650	3Z7	0.8610
651	DFU	0.8609
652	PPV	0.8609
653	ARB	0.8606
654	2TQ	0.8595
655	PEL	0.8589
656	I2M	0.8587
657	F81	0.8585
658	HMU	0.8583
659	SKG	0.8580
660	24B	0.8578
661	260	0.8577
662	JZ4	0.8574
663	PEA	0.8570
664	3NT	0.8551
665	CEE	0.8546
666	FUF	0.8537
667	MXN	0.8527

Similar Binding Sites (Proteins are less than 50% similar to leader)

Pocket No.: 1; Query (leader) PDB : 6HYY; Ligand: SER; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 1) in the query (biounit: 6hyy.bio1) has 15 residues
No:	Leader PDB	Ligand	Sequence Similarity

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