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Receptor
PDB id Resolution Class Description Source Keywords
6H5E 2.14 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE GATD/MURT ENZYME COMPLEX FROM STAPH AUREUS WITH BOUND AMPPNP STAPHYLOCOCCUS AUREUS CELL WALL BIOSYNTHESIS PEPTIDOGLYCAN ANTIBIOTIC RESISTANCEBIOSYNTHETIC PROTEIN
Ref.: STRUCTURAL BASIS OF CELL WALL PEPTIDOGLYCAN AMIDATI GATD/MURT COMPLEX OF STAPHYLOCOCCUS AUREUS. SCI REP V. 8 12953 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL C:302;
C:303;
C:304;
D:504;
D:505;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
ZN D:501;
B:501;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
PEG C:305;
D:506;
D:507;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
106.12 C4 H10 O3 C(COC...
MG B:503;
D:503;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP B:502;
D:502;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
144 C:301;
Invalid;
none;
submit data
122.143 C4 H12 N O3 C[N+]...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6H5E 2.14 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE GATD/MURT ENZYME COMPLEX FROM STAPH AUREUS WITH BOUND AMPPNP STAPHYLOCOCCUS AUREUS CELL WALL BIOSYNTHESIS PEPTIDOGLYCAN ANTIBIOTIC RESISTANCEBIOSYNTHETIC PROTEIN
Ref.: STRUCTURAL BASIS OF CELL WALL PEPTIDOGLYCAN AMIDATI GATD/MURT COMPLEX OF STAPHYLOCOCCUS AUREUS. SCI REP V. 8 12953 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 6H5E - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 6H5E - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 6H5E - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6H5E; Ligand: ANP; Similar sites found with APoc: 366
This union binding pocket(no: 1) in the query (biounit: 6h5e.bio2) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 1CR1 TTP 1.68919
2 5ZXD ATP 2.28833
3 5HCN GCP 2.29885
4 1YVD GNP 2.36686
5 1QHG ATP 2.39044
6 1RRC ADP 2.65781
7 1KK1 GNP 2.78884
8 3ITJ CIT 2.95858
9 1D8C GLV 2.97483
10 4H1V GNP 2.98103
11 5M04 GDP 3.05556
12 3FWY ADP 3.18471
13 3CV6 NAP 3.18725
14 1K6M AGS 3.18725
15 5TSH ADP 3.18725
16 1P7T PYR 3.20366
17 3TMK T5A 3.24074
18 1IZC PYR 3.24484
19 4R2I ANP 3.33333
20 1G3Q ADP 3.37553
21 5XC5 GTP 3.40909
22 1JJ7 ADP 3.46154
23 4QM7 GTP 3.50877
24 3Q85 GNP 3.5503
25 4LC1 GDP 3.56083
26 1Z2A GDP 3.57143
27 2VHJ ADP 3.58566
28 4ZG4 VO4 ADP 3.58566
29 4IHQ ADP 3.58566
30 2WJH GDP 3.61446
31 3GJ0 GDP 3.61991
32 3GJ4 GDP 3.61991
33 1IBR GNP 3.7037
34 2WJG GDP 3.7234
35 3QVV 3QV 3.72881
36 3QVV A3P 3.72881
37 5U32 GDP 3.81356
38 1L2T ATP 3.82979
39 3RUV ANP 3.8674
40 2W58 ADP 3.9604
41 2ZPA ADP 3.98406
42 4RD0 GDP 3.98406
43 2VVG ADP 4
44 3T1O GDP 4.0404
45 4V0K GDP 4.14201
46 3MD0 GDP 4.22535
47 5KUT GDP 4.2328
48 5OCG GNP 4.2328
49 2Q0D ATP 4.24929
50 3QPB URA 4.25532
51 6CS8 F9Y 4.29043
52 5XK9 GST 4.31034
53 5XK9 DMA 4.31034
54 1TQ4 GDP 4.35835
55 2FAH GDP 4.38247
56 2BEK ATP 4.38247
57 4WOP CTP 4.44444
58 1Z0F GDP 4.46927
59 2QG6 NMN 4.52261
60 3TK1 GDP 4.54545
61 2ZJ5 ADP 4.57666
62 3A4M ADP 4.61538
63 6FA4 GNP 4.62428
64 3ZQ6 ADP ALF 4.78088
65 3EC1 GDP 4.78088
66 2D4V NAD 4.78088
67 1WA5 GTP 4.78088
68 2GMV PEP 4.78088
69 2GMV UN8 4.78088
70 1O2D NAP 4.78088
71 3RWO GDP 4.78088
72 5X40 ACP 4.79452
73 1CLU DBG 4.81928
74 5WLB GNP 4.81928
75 1YZG GDP 5.02793
76 2BVN GNP 5.08906
77 1D8T GDP 5.08906
78 5Z69 AGS 5.10753
79 2J5V PCA 5.17928
80 3WXM GTP 5.17928
81 5BYK OAQ 5.17928
82 5BYK A3P 5.17928
83 3QKT ANP 5.17928
84 1XP8 AGS 5.17928
85 4KFU ACP 5.17928
86 1WF3 GNP 5.17928
87 1SKQ GDP 5.17928
88 4Q1A 2XZ 5.35714
89 4Q1A UDP 5.35714
90 4IOK XPO 5.49199
91 4IOK ADP 5.49199
92 1XKV ATP 5.49199
93 2C1X UDP 5.49199
94 1SQ5 ADP 5.51948
95 3DDC GNP 5.52147
96 1MR3 G3D 5.52486
97 1GOT GDP 5.57769
98 4U0S ADP 5.57769
99 1NVV GNP 5.57769
100 6D5V GNP 5.57769
101 4PJ3 ANP 5.57769
102 6BVK GNP 5.57769
103 6D5M GNP 5.57769
104 6D5G GNP 5.57769
105 6D5H GNP 5.57769
106 6D5J GNP 5.57769
107 6BVL GNP 5.57769
108 6D59 GNP 5.57769
109 6BVJ GNP 5.57769
110 6D5E GNP 5.57769
111 6BVI GNP 5.57769
112 6D5L GNP 5.57769
113 6D56 GNP 5.57769
114 6BVM GNP 5.57769
115 1YQT ADP 5.57769
116 6D55 GNP 5.57769
117 4NKT 2KH 5.57769
118 4TMK T5A 5.6338
119 1SVI GDP 5.64103
120 2XTZ GSP 5.64972
121 2VG1 FPP 5.70175
122 1LVK MNT BEF 5.72082
123 1OS1 PYR 5.72082
124 1OS1 ATP 5.72082
125 3CH5 GDP 5.76923
126 2UZI GTP 5.76923
127 1G3M PCQ 5.78231
128 1G3M A3P 5.78231
129 1VG8 GNP 5.7971
130 1VG0 GDP 5.7971
131 1Z0K GTP 5.7971
132 5UWQ GNP 5.94966
133 5DIF GNP 5.94966
134 5UWP GNP 5.94966
135 5UWS GNP 5.94966
136 5UWW GNP 5.94966
137 5UWJ GNP 5.94966
138 5UWU GNP 5.94966
139 4HAT GNP 5.94966
140 5UWR GNP 5.94966
141 5DHF GNP 5.94966
142 5UWI GNP 5.94966
143 5UWH GNP 5.94966
144 1W7J ADP BEF 5.96026
145 4BFW ZVW 5.9761
146 1Q3Q ANP 5.9761
147 3ZCN ATP 6.08466
148 4OI4 ATP 6.08696
149 2B8W ALF 5GP 6.09756
150 1FQK GDP 6.12245
151 5UIV ADP 6.1674
152 1S8F GDP 6.21469
153 1JJV ATP 6.31068
154 5TIV A3P 6.32411
155 5NM7 GLY 6.3745
156 3CV2 OXL 6.3745
157 6DEF GCP 6.3745
158 4P4T GDP 6.3745
159 1Z08 GNP 6.47059
160 1VG9 GDP 6.48649
161 1VG1 GDP 6.48649
162 3ZS9 ADP ALF 6.49718
163 2WOJ ADP ALF 6.49718
164 4U00 ADP 6.55738
165 2AWN ADP 6.56168
166 1FWV SGA MAG FUC 6.71642
167 2VWT PYR 6.74157
168 4PVV HO4 6.77291
169 1DAR GDP 6.77291
170 1G7S GDP 6.77291
171 1TAD ALF 6.77291
172 1TAD GDP 6.77291
173 4NON GDP 6.77291
174 1OIV GDP 6.80628
175 5Z2M GTP 6.81818
176 6B8B ADP 6.82731
177 3LOO B4P 6.84932
178 4X8O AP5 7.00935
179 2YOH WMJ 7.14286
180 6AU6 GDP 7.17131
181 2ABS ACP 7.17131
182 1MKY GDP 7.17131
183 2OFW ADX 7.21154
184 3TBK ANP 7.32265
185 1XX6 ADP 7.32984
186 5KSP GDP 7.36842
187 3QXC ATP 7.43802
188 1NN5 ANP 7.44186
189 1NN5 2DT 7.44186
190 3KTA AP5 7.51445
191 5E5U MLI 7.53769
192 2FSH ANP 7.56972
193 4YS0 ADP 7.56972
194 5KSZ GCP 7.56972
195 4B47 GDP 7.56972
196 2NCD ADP 7.61905
197 1KY3 GDP 7.69231
198 1JBW ACQ 7.71028
199 1JBW TMF 7.71028
200 1FZQ GDP 7.73481
201 4GBM A3P 7.73994
202 1O3Y GTP 7.83133
203 1J2J GTP 7.83133
204 1RE0 GDP 7.92683
205 1S9D GDP 7.92683
206 1W78 PD8 7.96813
207 1W78 ADP 7.96813
208 2WIC GNP 7.96813
209 4ONC 40B 7.96813
210 2VOS ADP 8.00915
211 1YRB GDP 8.01527
212 1XEX ATP 8.13953
213 1R2Q GNP 8.23529
214 3RLF ANP 8.23799
215 2RGX AP5 8.25243
216 1ZUI SKM 8.33333
217 2CJW GDP 8.33333
218 4NE2 SH2 8.36653
219 4NE2 ADP 8.36653
220 2PEZ DAT 8.37989
221 2PEZ GGZ 8.37989
222 2GKS ADP 8.46682
223 2Y65 ADP 8.49315
224 5N69 ADP 8.54271
225 2F9L GDP 8.54271
226 5O2T GSP 8.55615
227 1ZJ6 G3D 8.55615
228 2OM2 GDP 8.61539
229 5L3S GNP 8.72483
230 1F2U ATP 8.72483
231 4XVU ATP 8.75576
232 1CS4 GSP 8.76494
233 2D2F ADP 8.8
234 3GJ5 GDP 8.82353
235 1YZQ GNP 8.82353
236 1T5C ADP 8.88252
237 1BH2 GSP 8.88889
238 4LPS GDP 9.09091
239 3GJ3 GDP 9.09091
240 2OG2 MLI 9.16335
241 5L3R GCP 9.16335
242 3B9Q MLI 9.16335
243 2HT6 GDP 9.1954
244 1BG2 ADP 9.23077
245 4M9Q GNP 9.2511
246 1D5C GDP 9.25926
247 3IIJ ADP 9.44444
248 5BXQ GDP 9.44882
249 2CDN ADP 9.45274
250 3RAB GNP 9.46746
251 1M2O GNP 9.47368
252 2ZPT A3P 9.49153
253 5KDO GDP 9.49721
254 1UJ2 ADP 9.52381
255 1UJ2 C5P 9.52381
256 6G14 G4P 9.56175
257 2BO4 FLC 9.57179
258 1G7C 5GP 9.57447
259 2G77 GDP 9.59596
260 1SVK ALF GDP 9.63173
261 1MH1 GNP 9.67742
262 4K81 GTP 9.68992
263 2HF9 GSP 9.73451
264 1KK8 BEF ADP 9.74026
265 1Z0A GDP 9.77011
266 2D7D ADP 9.96016
267 2ODE ALF GDP 10
268 1G16 GDP 10
269 1Z06 GNP 10.0529
270 3AB3 GDP 10.1626
271 3BC1 GNP 10.1695
272 1KSH GDP 10.2151
273 1ZC3 GNP 10.2857
274 3CX8 GSP 10.3448
275 4PFO ADP 10.3586
276 1QHH ATP 10.3586
277 1A4R GDP 10.4712
278 4ITR GDP 10.4712
279 1GRN GDP 10.4712
280 1A4R GNH 10.4712
281 3M1I GTP 10.5023
282 5LB3 ADP 10.5263
283 2QN6 GDP 10.7527
284 2QTV GNP 10.7784
285 4XTR ATP 10.8108
286 4XTR ADP 10.8108
287 4HI0 GDP 11.0553
288 2FFQ GSP 11.1111
289 1RJ9 GCP 11.1554
290 1Q19 SSC 11.1554
291 1EK0 GNP 11.1765
292 1F6B GDP 11.6162
293 6BSX GDP 11.7978
294 6BSX E7S 11.7978
295 1VHT BA3 11.9266
296 2IYL GDP 11.9718
297 2CK3 ADP 12
298 3QF7 ANP 12
299 4HUT ATP 12.0419
300 1DAK ADP 12.0536
301 1DAK DPU 12.0536
302 1G6H ADP 12.4514
303 3ZL8 ADP 12.5858
304 2VB6 ADP BEF 12.7517
305 5UWT GNP 13.0435
306 1PUJ GNP 13.1206
307 3GJ7 GDP 13.2653
308 5FG3 GDP 13.2723
309 3PQC GDP 13.3333
310 5O74 GDP 13.3333
311 2GJ8 ALF GDP 13.3721
312 6C0B MLI 13.4615
313 1OXV ANP 13.5458
314 1M7G ADP 13.7441
315 1M7G ADX 13.7441
316 1LFD GNP 13.7931
317 2C77 GNP 13.9442
318 3T12 GDP ALF 13.9706
319 5XKT GNP 14
320 3GJ8 GDP 14.1304
321 3ZC7 ATP 14.2857
322 3MJH GTP 14.7059
323 2C78 GNP 14.741
324 4DCT GDP 14.741
325 1D2E GDP 14.741
326 1GUA GNP 14.9701
327 4HDO GNP 14.9701
328 1KAO GDP 14.9701
329 3ETG NDP 15.1394
330 3ETG GTP 15.1394
331 3ETG GLU 15.1394
332 1TU3 GNP 15.1899
333 1B0U ATP 15.2672
334 3T5G GDP 15.7895
335 5TB5 GDP 16
336 2KIN ADP 16
337 2Z5F A3P 16.1074
338 5TAR GDP 16.2162
339 2A5F GTP 16.5714
340 4CVN ADP 16.7883
341 4R98 GNH 17.1315
342 1UPT GTP 17.5439
343 1P3D ANP 17.6842
344 4BAS GNP 18.0905
345 1R4A GNP 18.1818
346 1GQY ACP 18.5263
347 3W5J GDP 18.6275
348 1FQJ GDP 19.0476
349 1JI0 ATP 19.1667
350 6C90 ADP 19.2308
351 1U8Z GDP 19.6429
352 4A4Z ANP 20.7171
353 6CRK GDP 21.1268
354 1GP2 GDP 21.1268
355 2HCJ GDP 21.6216
356 3SBD GNP 21.9251
357 2W2X GSP 23.2432
358 1Z0J GTP 23.7288
359 2VTD LKM 25.3933
360 1DS6 GDP 29.1667
361 4C12 ADP 29.9771
362 6CIT GNP 33.3333
363 5UWO GNP 35
364 1Y3A GDP 43.75
365 5DI9 GNP 47.619
366 5YT0 GDP 47.619
Pocket No.: 2; Query (leader) PDB : 6H5E; Ligand: ANP; Similar sites found with APoc: 39
This union binding pocket(no: 2) in the query (biounit: 6h5e.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1OE0 TTP 2.6087
2 1ZRH A3P 2.91971
3 2V5K OXM 3.13589
4 1KEV NDP 3.98406
5 2WW4 ADP 3.98406
6 3COB ADP 3.98406
7 5GVR LMR 4.2735
8 2Q2Y ADP 4.35967
9 2Q2Y MKR 4.35967
10 1T8U UAP SGN IDS SGN 4.41176
11 1TL2 NDG 4.66102
12 1NHX FTB 4.78088
13 1NHX PEP 4.78088
14 4L80 OXL 5.17241
15 1PZG A3D 5.17928
16 2BHZ MAL 5.57769
17 1HYH NAD 5.57769
18 3JZ4 NAP 5.57769
19 3BFX A3P 5.57769
20 1GWN GTP 6.34146
21 1GXU 2HP 6.59341
22 1M7B GTP 7.06522
23 4DDY DN6 7.22433
24 4KGD TDP 8.00915
25 5YVT NAI 8.36653
26 3BFV ADP 8.36653
27 4ZY1 4U5 8.36653
28 2WCU FUC 9.39597
29 3WG6 NDP 9.56175
30 3Q72 GNP 10.8434
31 3KIF GDL 11.3208
32 3VPH NAD 11.9355
33 1MJT NAD 12.1037
34 3KIH GDL 12.3711
35 1NF3 GNP 14.0625
36 4BQS ADP 14.2045
37 4BQS K2Q 14.2045
38 3H4S ADP 16.2963
39 1R37 NAD 17.5793
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