Receptor
PDB id Resolution Class Description Source Keywords
6GYT 2.5 Å EC: 2.3.1.48 TRANSCRIPTION FACTOR DIMERIZATION ACTIVATES THE P300 ACETYLT HOMO SAPIENS P300 CBP ACETYLTRANSFERASE CHROMATIN TRANSCRIPTIONAL REGGENE REGULATION
Ref.: TRANSCRIPTION FACTOR DIMERIZATION ACTIVATES THE P30 ACETYLTRANSFERASE. NATURE V. 562 538 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ZN B:1301;
A:1301;
B:1302;
A:1302;
 Part of Protein;
Part of Protein;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
65.409 Zn [Zn+2...
GLY LEU GLY ALY GLY GLY ALA ALY ALA C:9;
 Valid;
 Atoms found LESS than expected: % Diff = 0.017;
 submit data
826.974 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6GYT 2.5 Å EC: 2.3.1.48 TRANSCRIPTION FACTOR DIMERIZATION ACTIVATES THE P300 ACETYLT HOMO SAPIENS P300 CBP ACETYLTRANSFERASE CHROMATIN TRANSCRIPTIONAL REGGENE REGULATION
Ref.: TRANSCRIPTION FACTOR DIMERIZATION ACTIVATES THE P30 ACETYLTRANSFERASE. NATURE V. 562 538 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 64 families.
1 6GYT - GLY LEU GLY ALY GLY GLY ALA ALY ALA n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 6GYT - GLY LEU GLY ALY GLY GLY ALA ALY ALA n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 25 families.
1 6GYT - GLY LEU GLY ALY GLY GLY ALA ALY ALA n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GLY LEU GLY ALY GLY GLY ALA ALY ALA; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 GLY LEU GLY ALY GLY GLY ALA ALY ALA 1 1
2 GLY GLY ALY ALA PRO ARG LYS GLN 0.604651 0.928571
3 LYS GLY GLY ALA ALY ARG HIS ARG LYS ILE 0.441176 0.689655
4 ALA GLY GLY ALA ALA ALA ALA ALA 0.434783 0.809524
5 GLY 5GG GLY ALA 0.428571 0.883721
6 LYS GLY GLY ALA ALY ARG HIS ARG 0.422222 0.666667
7 GLY ALA ALY ARG HIS ARG 0.408602 0.904762
8 ALA ALA LEU THR ARG ALA 0.401786 0.666667
9 GLY LEU TYR ALA SER LYS LEU ALA 0.4 0.709091
Similar Ligands (3D)
Ligand no: 1; Ligand: GLY LEU GLY ALY GLY GLY ALA ALY ALA; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6GYT; Ligand: GLY LEU GLY ALY GLY GLY ALA ALY ALA; Similar sites found with APoc: 20
This union binding pocket(no: 1) in the query (biounit: 6gyt.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 4YC9 4C1 29.1925
2 4UYG 73B 31.2102
3 4UYG 73B 31.2102
4 4UYG 73B 31.2102
5 4UYG 73B 31.2102
6 4UYG 73B 31.2102
7 4UYG 73B 31.2102
8 4BJX 73B 32.0261
9 4UYF 73B 32.4675
10 4UYF 73B 32.4675
11 2YDW WSH 32.6797
12 2YDW WSH 32.6797
13 5VOM 9GY 32.8859
14 5VOM 9GY 32.8859
15 6C7R EO4 39.2
16 5WUU 7UU 42.446
17 5N18 8HZ 44.0367
18 6VIX QYV 45.4545
19 4FLP JQ1 46.2185
20 4FLP JQ1 46.2185
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