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Receptor
PDB id Resolution Class Description Source Keywords
6F5Z 1.35 Å EC: 2.-.-.- COMPLEX BETWEEN THE HALOFERAX VOLCANII TRM112 METHYLTRANSFER ACTIVATOR AND THE HVO_0019 PUTATIVE METHYLTRANSFERASE HALOFERAX VOLCANII PROTEIN COMPLEX HOLOENZYME METHYLTRANSFERASE HALOPHILE ATRANSFERASE
Ref.: EVOLUTIONARY INSIGHTS INTO TRM112-METHYLTRANSFERASE HOLOENZYMES INVOLVED IN TRANSLATION BETWEEN ARCHAEA EUKARYOTES. NUCLEIC ACIDS RES. V. 46 8483 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL C:101;
B:301;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SAH B:302;
A:301;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6F5Z 1.35 Å EC: 2.-.-.- COMPLEX BETWEEN THE HALOFERAX VOLCANII TRM112 METHYLTRANSFER ACTIVATOR AND THE HVO_0019 PUTATIVE METHYLTRANSFERASE HALOFERAX VOLCANII PROTEIN COMPLEX HOLOENZYME METHYLTRANSFERASE HALOPHILE ATRANSFERASE
Ref.: EVOLUTIONARY INSIGHTS INTO TRM112-METHYLTRANSFERASE HOLOENZYMES INVOLVED IN TRANSLATION BETWEEN ARCHAEA EUKARYOTES. NUCLEIC ACIDS RES. V. 46 8483 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 6F5Z - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 6F5Z - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 6F5Z - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6F5Z; Ligand: SAH; Similar sites found with APoc: 785
This union binding pocket(no: 1) in the query (biounit: 6f5z.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 6FX2 FUC C4W NAG BMA MAN NAG GAL None
2 1E6W NAD 1.2987
3 1E3W NAD 1.2987
4 2BZG SAH 1.7316
5 6BT6 3GK 1.7316
6 3ZV6 4HB 1.7316
7 3ZV6 NAD 1.7316
8 4NBU NAI 2
9 3QWI NAP 2.1645
10 3QWI CUE 2.1645
11 4X9M FAD 2.1645
12 1T26 NAI 2.17391
13 1T26 GBD 2.17391
14 3OID NDP 2.32558
15 5BUK FAD 2.5974
16 5GT9 NAP 2.5974
17 3H8V ATP 2.73973
18 3U4C NDP 2.84698
19 3GRU AMP 3.0303
20 3DXY SAM 3.0303
21 1BC5 SAH 3.0303
22 5G3U ITW 3.0303
23 5G3U FDA 3.0303
24 6BWL NAD 3.0303
25 1GZ6 NAI 3.0303
26 1ZBQ NAD 3.0303
27 4YAC NAI 3.0303
28 6CI9 NAP 3.0303
29 1V8B NAD 3.0303
30 2A92 NAI 3.0303
31 5T2U NAP 3.0303
32 4AZW SAM 3.27869
33 1H82 GZZ 3.27869
34 1H82 FAD 3.27869
35 5L95 AMP 3.27869
36 1Q0S SAH 3.4632
37 3S5W FAD 3.4632
38 1FEC FAD 3.4632
39 3ZNN FAD 3.4632
40 3ZNN 4WL 3.4632
41 1OC2 NAD 3.4632
42 1OC2 TDX 3.4632
43 2Q28 ADP 3.4632
44 4FC7 NAP 3.4632
45 4FC7 COA 3.4632
46 1G2O IMH 3.4632
47 5K4W NAI 3.4632
48 5K4W THR 3.4632
49 3SJU NDP 3.4632
50 4NTC FAD 3.58209
51 3DMH GMP 3.8961
52 3DMH SAM 3.8961
53 3GF4 FAD 3.8961
54 3GF4 UPG 3.8961
55 4ZCC FAD 3.8961
56 4ZCC NAI 3.8961
57 2Z3Y F2N 3.8961
58 3RIY NAD 3.8961
59 6EQS BV8 3.8961
60 1U3G ADP 4.2328
61 3BGD SAH 4.329
62 3X0V FAD 4.329
63 3BGD PM6 4.329
64 4EMI NAD 4.329
65 4EMI FAD 4.329
66 4EMJ FAD 4.329
67 5KMS FAD 4.329
68 5KMS NAD 4.329
69 1X87 NAD 4.329
70 3C3Y SAH 4.329
71 1TE2 PGA 4.42478
72 4BQS ADP 4.54545
73 2UVO NAG 4.67836
74 3WLE NAD 4.69208
75 2DT5 NAD 4.73934
76 5TS5 FAD 4.7619
77 1NW5 SAM 4.7619
78 1RSG FAD 4.7619
79 4MO2 FDA 4.7619
80 3CH6 311 4.7619
81 3CH6 NAP 4.7619
82 4MO2 FAD 4.7619
83 3VZS NAP 4.7619
84 4RDN 6MD 4.79042
85 1Q9I FAD 4.91803
86 1Q9I TEO 4.91803
87 6FHO FAD 4.91803
88 1E5Q NDP 4.91803
89 1E1M NAP 4.91803
90 1E1M FAD 4.91803
91 1XHL NDP 4.91803
92 3SJ7 NDP 4.91803
93 2WA2 SAM 4.91803
94 1E6E FAD 4.91803
95 1U7T TDT 4.91803
96 2Q1W NAD 4.91803
97 3LCC SAH 5.19481
98 5FUB SAH 5.19481
99 1C0I BE2 5.19481
100 1C0I FAD 5.19481
101 5A1S FLC 5.19481
102 1XKQ NDP 5.19481
103 4GKV NAD 5.19481
104 5UAO FAD 5.19481
105 4DA6 GA2 5.19481
106 3FZG SAM 5.5
107 3A27 SAM 5.51471
108 6D6Y SAH 5.62771
109 4FN4 NAD 5.62771
110 1ZK7 FAD 5.62771
111 3LZW NAP 5.62771
112 5DF1 NAP 5.62771
113 5DF1 58X 5.62771
114 3LZW FAD 5.62771
115 1LTH NAD 5.62771
116 1XCL SAH 6.06061
117 4YAG NAI 6.06061
118 2O07 SPD 6.06061
119 2O07 MTA 6.06061
120 5D4V SAH 6.06061
121 2DTX BMA 6.06061
122 1RM0 D6P 6.06061
123 1RM0 NAI 6.06061
124 2AQJ TRP 6.06061
125 2AQJ FAD 6.06061
126 1M7G AV2 6.16114
127 5ZW3 SAH 6.22222
128 5OC1 FAD 6.49351
129 1JA9 NDP 6.49351
130 3WGT FAD 6.49351
131 3WGT QSC 6.49351
132 2PXX SAH 6.55738
133 3X0D SAH 6.55738
134 5ICE SAH 6.55738
135 5ICE 2H4 6.55738
136 3PT9 SAH 6.55738
137 3VSE SAH 6.55738
138 5O42 9JW 6.55738
139 5O42 BGC 6.55738
140 5O42 NAD 6.55738
141 3AYI FAD 6.55738
142 3AYI HCI 6.55738
143 5ZHO A2G GLA FUC 6.55738
144 4KGD FAD 6.55738
145 4KGD TDP 6.55738
146 1EDO NAP 6.55738
147 5O4J 9KH 6.55738
148 2VVM FAD 6.55738
149 5O4J SAH 6.55738
150 5O4J PJL 6.55738
151 4REP FAD 6.55738
152 2VVL FAD 6.55738
153 2GMH FAD 6.55738
154 3T31 FAD 6.55738
155 3T31 DCQ 6.55738
156 3RKR NAP 6.55738
157 5JAQ NAI 6.55738
158 2ZXI FAD 6.55738
159 3ML1 MGD 6.66667
160 5N0J FAD 6.92641
161 2PT9 2MH 6.92641
162 2I7C AAT 6.92641
163 2PT9 S4M 6.92641
164 1L5Y BEF 6.92641
165 2R4J 13P 6.92641
166 2R4J FAD 6.92641
167 3QVP FAD 6.92641
168 2EWM NAD 6.92641
169 1P1C SAH 7.03518
170 1L1E SAH 7.35931
171 1RJD SAM 7.35931
172 4MOP 2H5 7.35931
173 1NAA 6FA 7.35931
174 1NAA ABL 7.35931
175 4LHD GLY 7.35931
176 2FR1 NDP 7.35931
177 2HK9 ATR 7.35931
178 3NUG NAD 7.35931
179 2HK9 NAP 7.35931
180 3WV8 ATP 7.35931
181 2FKA BEF 7.75194
182 1U2Z SAH 7.79221
183 3ELW SAM 7.79221
184 3ELW GP3 7.79221
185 4URF NAD 7.79221
186 5FJN FAD 7.79221
187 5FJN BE2 7.79221
188 1RYI GOA 7.79221
189 1RYI FAD 7.79221
190 3FGZ BEF 7.8125
191 1JQD SAH 8.19672
192 2AOT SAH 8.19672
193 3G2O SAM 8.19672
194 2EFJ SAH 8.19672
195 2EG5 SAH 8.19672
196 1JQD HSM 8.19672
197 5ERG SAM 8.19672
198 5BJX NAD 8.19672
199 5BJX UDP 8.19672
200 4JCA CIT 8.19672
201 3QJ4 FAD 8.19672
202 2NVK FAD 8.19672
203 3GCZ SAM 8.19672
204 2IV2 MGD 8.19672
205 4HA6 FAD 8.19672
206 2IZ1 ATR 8.19672
207 6EL3 NAP 8.19672
208 1ORR NAD 8.19672
209 1KNR FAD 8.19672
210 2IV2 2MD 8.19672
211 5KOX RFP 8.19672
212 5KOX FAD 8.19672
213 4TM3 FAD 8.19672
214 3NYC IAR 8.19672
215 3NYC FAD 8.19672
216 1SB8 NAD 8.19672
217 1SB8 UD2 8.19672
218 6F3N NAD 8.19672
219 6F3N ADN 8.19672
220 6F3M NAD 8.19672
221 4RDH AMP 8.19672
222 5D85 FLC 8.19672
223 2Y6Q I7T 8.19672
224 2Y6Q FAD 8.19672
225 1GOJ ADP 8.19672
226 3AB1 FAD 8.19672
227 1SZD APR 8.19672
228 4RDI ATP 8.19672
229 2PX8 SAH 8.19672
230 1MXG ACR 8.19672
231 2OD9 A1R NCA 8.19672
232 2Q0L FAD 8.19672
233 5JWC FAD 8.22511
234 4UCI SAM 8.22511
235 4POO SAM 8.5
236 5W7M SAH 8.65801
237 1G60 SAM 8.65801
238 1N2X SAM 8.65801
239 5XNC MTA 8.65801
240 4D5G FAD 8.65801
241 4D5G TPP 8.65801
242 2XVF FAD 8.65801
243 2KIN ADP 9
244 4Z24 FAD 9.09091
245 2XVE FAD 9.09091
246 1G55 SAH 9.52381
247 3H5N ATP 9.52381
248 6DUB SAH 9.83607
249 5KOK SAH 9.83607
250 5KOK S9T 9.83607
251 5KOK R9T 9.83607
252 1XDS SAM 9.83607
253 5FTW SAH 9.83607
254 4DMG SAM 9.83607
255 4RSL FAD 9.83607
256 1REO FAD 9.83607
257 4OPC FDA 9.83607
258 4OPC PGT 9.83607
259 5J60 FAD 9.83607
260 4RW3 TDA 9.83607
261 1YBH FAD 9.83607
262 4NTD FAD 9.83607
263 6F97 FAD 9.83607
264 3KLJ FAD 9.83607
265 4L2I FAD 9.83607
266 3OZ2 FAD 9.83607
267 2CDU FAD 9.83607
268 4N49 SAM 9.83607
269 1GET NAP 9.83607
270 1GET FAD 9.83607
271 5M67 3D1 9.83607
272 5M67 ADE 9.83607
273 4IV9 FAD 9.83607
274 4GUT FAD 9.83607
275 5M67 NAD 9.83607
276 4B63 ORN 9.83607
277 4B63 FAD 9.83607
278 4B63 NAP 9.83607
279 4GUS FAD 9.83607
280 4HSU FAD 9.83607
281 4FWE FAD 9.83607
282 2AE2 PTO 9.83607
283 3NJ4 AFX 9.83607
284 3IHG FAD 9.83607
285 3LU1 NAD 9.83607
286 5EB4 FAD 9.83607
287 2FZW NAD 9.83607
288 5I39 FAD 9.83607
289 6AIN FAD 9.83607
290 2ZJ1 NAD 9.83607
291 3NJ4 NAD 9.83607
292 3Q9T FAY 9.83607
293 2ZJ1 ARJ 9.83607
294 2AE2 NAP 9.83607
295 1PS9 FAD 9.83607
296 1KEW NAD 9.83607
297 1Y8Q ATP 9.83607
298 4BJZ P3A 9.83607
299 4BJZ FAD 9.83607
300 1PL6 NAD 9.83607
301 6GAR FAD 9.83607
302 1MV8 NAD 9.83607
303 4UZI IMD 9.83607
304 2CDU ADP 9.83607
305 3IA4 NDP 9.83607
306 4EIP FAD 9.83607
307 1PL6 572 9.83607
308 1NM5 NAD 9.83607
309 1SQL GUN 9.83607
310 3FG2 FAD 9.83607
311 3VPH OXM 9.83607
312 3VPH NAD 9.83607
313 2E7Z MGD 9.83607
314 1GY8 NAD 9.83607
315 1AOE NDP 9.89583
316 1AOE GW3 9.89583
317 4M37 SAH 9.95671
318 5FEU NAP 9.95671
319 5FFF 5XC 9.95671
320 4CQM NAP 9.95671
321 5FFF NAP 9.95671
322 1IY8 NAD 9.95671
323 3GWZ SAH 10.3896
324 3GXO SAH 10.3896
325 1YY5 FAD 10.3896
326 1Q1R FAD 10.3896
327 2HMT NAI 10.4167
328 3JWH SAH 10.5991
329 2YX1 SFG 10.8225
330 4DCM SAM 10.8225
331 2WPF FAD 10.8225
332 2WPF WPF 10.8225
333 1WVG APR 10.8225
334 1H0H MGD 10.8225
335 5W7R SAH 11.2554
336 3HDY GDU 11.2554
337 3HDY FDA 11.2554
338 3HDY FAD 11.2554
339 5W7R 9Z7 11.2554
340 2V6G NAP 11.2554
341 3A25 SAM 11.2554
342 4D79 ATP 11.2554
343 3G89 SAM 11.4754
344 5E8J SAH 11.4754
345 3FRH SAH 11.4754
346 5E9W SAH 11.4754
347 3FPF TNA 11.4754
348 3FPF MTA 11.4754
349 2ZWA SAH 11.4754
350 4ONQ SFG 11.4754
351 2IVD FAD 11.4754
352 1ELI PYC 11.4754
353 3L9W AMP 11.4754
354 3L9W GSH 11.4754
355 1NV8 MEQ 11.4754
356 2JB2 FAD 11.4754
357 2JB2 PHE 11.4754
358 6GFK SAH 11.4754
359 1NV8 SAM 11.4754
360 5XLX SAH 11.4754
361 3SSO SAH 11.4754
362 5HSA FAS 11.4754
363 1MO9 FAD 11.4754
364 4RPL 3UC 11.4754
365 4RPL FAD 11.4754
366 1MO9 KPC 11.4754
367 3MAG SAH 11.4754
368 3MCT SAH 11.4754
369 4C3Y FAD 11.4754
370 4C3Y ANB 11.4754
371 4YNU FAD 11.4754
372 4YNU LGC 11.4754
373 4ITU NAI 11.4754
374 1VL8 NAP 11.4754
375 4ITU 1HS 11.4754
376 1UDB NAD 11.4754
377 1UDB UFG 11.4754
378 3D3W NAP 11.4754
379 1PR9 NAP 11.4754
380 3U31 NAD 11.4754
381 5Z2L NDP 11.4754
382 2YY7 NAD 11.4754
383 3CBG SAH 11.4754
384 1COY FAD 11.4754
385 1S7G APR 11.4754
386 1BW9 NAD 11.4754
387 5Y77 FAD 11.4754
388 3HB5 NAP 11.4754
389 6GAS FAD 11.4754
390 4YDD MGD 11.4754
391 4YDD MD1 11.4754
392 5E5U MLI 11.4754
393 2VHW NAI 11.4754
394 5A3B APR 11.4754
395 5NA1 FAD 11.4754
396 3ABI NAD 11.4754
397 2IVD ACJ 11.4754
398 1COY AND 11.4754
399 1O5O U5P 11.4754
400 4KWI NAP 11.4754
401 1PJS NAD 11.4754
402 1S7G NAD 11.4754
403 4KWI 1TJ 11.4754
404 1KYQ NAD 11.4754
405 1BXK NAD 11.4754
406 1KPG SAH 11.6883
407 3I53 SAH 11.6883
408 2BRY FAD 11.6883
409 4TXI FAD 11.6883
410 4PLT OXM 12.0846
411 4PLT NAI 12.0846
412 3DUW SAH 12.1076
413 3GEG NAD 12.1212
414 3EVG SAH 12.5541
415 2P41 SAH 12.5541
416 5YB7 ORN 12.5541
417 5YB7 FAD 12.5541
418 2FK8 SAM 13.1148
419 5X62 SAH 13.1148
420 2A14 SAH 13.1148
421 3O7W SAM 13.1148
422 1QAN SAH 13.1148
423 2EJU SAH 13.1148
424 2IID FAD 13.1148
425 2IID PHE 13.1148
426 2ZIF SAM 13.1148
427 4U8P UDP 13.1148
428 4U8P FDA 13.1148
429 5VN0 FAD 13.1148
430 5VN0 NAI 13.1148
431 5MBX FAD 13.1148
432 5MBX SP5 13.1148
433 3C6K SPD 13.1148
434 1XHC FAD 13.1148
435 5JCM NAD 13.1148
436 5JCM FAD 13.1148
437 5JCM ISD 13.1148
438 3CGD FAD 13.1148
439 3AXB FAD 13.1148
440 3AXB PRO 13.1148
441 5WGR FAD 13.1148
442 3C6K MTA 13.1148
443 4J4H 1J1 13.1148
444 4J4H NAI 13.1148
445 3CGD COA 13.1148
446 4JK3 NAD 13.1148
447 1T9D P25 13.1148
448 4D7E FAD 13.1148
449 1T9D 1MM 13.1148
450 1T9D PYD 13.1148
451 2CUL FAD 13.1148
452 5WKC FAD 13.1148
453 3CGD NAD 13.1148
454 3CGB FAD 13.1148
455 5THQ NDP 13.1148
456 1T9D FAD 13.1148
457 1R6D NAD 13.1148
458 1R6D DAU 13.1148
459 2VPY MGD 13.1148
460 6F9Q NAD 13.1148
461 5ZZ6 NAD 13.1148
462 4USR FAD 13.1148
463 1L7N ALF 13.1148
464 2VT3 ATP 13.1148
465 3WMX NAD 13.1148
466 4OM8 NAD 13.1148
467 1Q7B NAP 13.1148
468 4M73 SAH 13.4199
469 4M73 M72 13.4199
470 5GWX SAM 13.4199
471 5GWX SAR 13.4199
472 5YJI 8WO 13.4199
473 5YJI SAH 13.4199
474 3GDH SAH 13.4199
475 3EGI ADP 13.5922
476 1KYZ SAH 13.8528
477 1KYZ FER 13.8528
478 1V5F TPP 13.8528
479 1V5F FAD 13.8528
480 3UCL NAP 13.8528
481 3UCL CYH 13.8528
482 3UCL FAD 13.8528
483 6ER9 FAD 13.8528
484 6ER9 NAP 13.8528
485 1KQF MGD 13.8528
486 2OBF SAH 14.5329
487 2OBF F83 14.5329
488 1R18 SAH 14.5374
489 5DM1 SAH 14.7186
490 5DM1 5D7 14.7186
491 4C4A SAH 14.7541
492 4X60 3XV 14.7541
493 4X60 SFG 14.7541
494 3FUU ADN 14.7541
495 5FWA J7C 14.7541
496 1WY7 SAH 14.7541
497 1JQ3 AAT 14.7541
498 3EVF SAH 14.7541
499 3EVF GTA 14.7541
500 2BD0 NAP 14.7541
501 3K7M FAD 14.7541
502 5ZYN FAD 14.7541
503 3VYW SAM 14.7541
504 1UWK URO 14.7541
505 1UWK NAD 14.7541
506 4USQ FAD 14.7541
507 3LXD FAD 14.7541
508 3TKA SAM 14.7541
509 3QFA FAD 14.7541
510 4J36 1HR 14.7541
511 5MLR GRQ 14.7541
512 5MLR NAP 14.7541
513 6FP4 FAD 14.7541
514 4J36 FAD 14.7541
515 3S1S SAH 14.7541
516 2V3V MGD 14.7541
517 3GD4 FAD 14.7541
518 3GD4 NAD 14.7541
519 6FP4 E1T 14.7541
520 4J1Q NDP 14.7541
521 1P77 ATR 14.7541
522 5NMX FAD 14.7541
523 3VSV XYP 14.7541
524 5NMX NAP 14.7541
525 1MUU NAD 14.7541
526 2JHP SAH 14.7541
527 2WSB NAD 14.7541
528 6FBZ MGP 14.7541
529 4EYG VNL 14.7541
530 3HVJ 705 15.1515
531 1WG8 SAM 15.1515
532 5CUQ NSC 15.1515
533 5JJR SAH 15.1515
534 4XUC 43G 15.1515
535 4XUC SAM 15.1515
536 6GKV SAH 16.3934
537 5K0A FAD 16.3934
538 5MIT FAD 16.3934
539 5MIT NAP 16.3934
540 2Q7V FAD 16.3934
541 2QA1 FAD 16.3934
542 2Q46 NAP 16.3934
543 5J5Z FAD 16.3934
544 3OND NAD 16.3934
545 3OND ADN 16.3934
546 3O03 NAP 16.3934
547 3RNM FAD 16.3934
548 1EU1 MGD 16.3934
549 6FDF SAH 16.3934
550 4K5S FAD 16.3934
551 4K5S PM0 16.3934
552 2F5Z FAD 16.3934
553 4XFR CIT 16.3934
554 5X68 FAD 16.3934
555 3UOY NAP 16.3934
556 3UOY FAD 16.3934
557 4II2 ATP 16.3934
558 3M6W SAM 16.3934
559 5EOW FAD 16.3934
560 5K8P 6R8 16.3934
561 4RQU NAD 16.3934
562 3NDJ JHZ 16.4502
563 3NDJ SAH 16.4502
564 1BZL GCG 16.4502
565 1BZL FAD 16.4502
566 5EEH P9P 16.8831
567 5EEH SAH 16.8831
568 3BPX SAL 16.8919
569 5DLY SAH 17.316
570 5DLY 5D7 17.316
571 2NXE SAM 17.316
572 2DPM SAM 17.316
573 3NKS FAD 17.316
574 3EYA FAD 17.316
575 2VDV SAM 17.4797
576 1I1N SAH 17.7489
577 3GU3 SAH 17.7489
578 3P9C SAH 17.7489
579 6B92 SAH 18.0328
580 4YUW 4JU 18.0328
581 4YUW S4M 18.0328
582 1QO8 FAD 18.0328
583 1D4D FAD 18.0328
584 6ACS CIT 18.0328
585 4J56 FAD 18.0328
586 1G0N NDP 18.0328
587 1G0N PHH 18.0328
588 1GPE FAD 18.0328
589 5E1M PRO PRO LYS ARG ILE ALA 18.0328
590 5E1M SAH 18.0328
591 5TTJ FAD 18.0328
592 1AE1 NAP 18.0328
593 4HXY NDP 18.0328
594 2RGO FAD 18.0328
595 4Y9D NAI 18.0328
596 5OJI NAP 18.0328
597 5OJI ISN 18.0328
598 3K6V CIT 18.0328
599 2Z49 AMG 18.0328
600 4Y30 SAH 18.1818
601 4Y30 49L 18.1818
602 1QZZ SAM 18.1818
603 2A8X FAD 18.1818
604 4M52 FAD 18.1818
605 4M52 M52 18.1818
606 1EJ0 SAM 18.6147
607 5MGZ SAH 19.0476
608 5YF1 SFG 19.0476
609 5YF1 8V0 19.0476
610 2JJQ SAH 19.0476
611 5M58 SAH 19.4805
612 3QOX SAH 19.6721
613 5MW4 5JU 19.6721
614 5BVA FAD 19.6721
615 3E1T FAD 19.6721
616 6BQ6 TER 19.6721
617 5TWB FAD 19.6721
618 3AD8 NAD 19.6721
619 2GAG NAD 19.6721
620 4YSX FAD 19.6721
621 3AD8 PYC 19.6721
622 3AD8 FAD 19.6721
623 2GAG FAD 19.6721
624 2GAG FOA 19.6721
625 4PIO AVI 19.6721
626 4PIO SAH 19.6721
627 5ODQ FAD 19.6721
628 2C7G ODP 19.6721
629 2C7G FAD 19.6721
630 4MIG G3F 19.6721
631 5EJ2 NAD 19.6721
632 1RJW ETF 19.6721
633 2YG3 FAD 19.9134
634 4G5H UD7 19.9134
635 4G5H NAP 19.9134
636 1ZQ9 SAM 20.3463
637 4QAR ADE 20.8955
638 4BLW SAH 21.2121
639 4BLW AMP 21.2121
640 5MPT SAH 21.3115
641 1LSS NAD 21.3115
642 4D04 FAD 21.3115
643 4D04 NAP 21.3115
644 4YKG NAD 21.3115
645 4YKG FAD 21.3115
646 1FL2 FAD 21.3115
647 1G8K MGD 21.3115
648 6F7L FAD 21.3115
649 3CTY FAD 21.3115
650 1V59 FAD 21.3115
651 1GTE FAD 21.3115
652 1R27 MGD 21.3115
653 5XL4 SIA 21.3115
654 1NJR XYL 21.3115
655 1RPN NDP 21.3115
656 1SAY PYR 21.3115
657 4JDR FAD 21.3115
658 2PZM NAD 21.3115
659 2PZM UDP 21.3115
660 1UAY ADN 21.3115
661 1V59 NAD 21.3115
662 1TPY SAH 22.0779
663 3TKY SAH 22.0779
664 2UYQ SAM 22.0779
665 4R6W PC 22.5108
666 4R6W SAH 22.5108
667 4AT0 FAD 22.5108
668 1VE3 SAM 22.9075
669 2XVM SAH 22.9437
670 5W7K SAH 22.9508
671 2HQM FAD 22.9508
672 1PN0 FAD 22.9508
673 1PN0 IPH 22.9508
674 4FZV SAM 22.9508
675 4BV6 FAD 22.9508
676 2YVF FAD 22.9508
677 2YVF NAD 22.9508
678 1LVL FAD 22.9508
679 5G5G MCN 22.9508
680 1LVL NAD 22.9508
681 2YVJ FAD 22.9508
682 4A6D SAM 23.8095
683 4XQC 13D 23.8095
684 4XQC NAD 23.8095
685 5THY SAH 24.5902
686 5THZ SAH 24.5902
687 3Q87 SAM 24.5902
688 5BRT CH9 24.5902
689 5BRT FAD 24.5902
690 4JNA FAD 24.5902
691 6H3O FAD 24.5902
692 1DMR PGD 24.5902
693 2IVF MGD 24.5902
694 3NTA FAD 24.5902
695 3NTD FAD 24.5902
696 3NT6 FAD 24.5902
697 5WP4 SAH 24.6753
698 3MB5 SAM 24.6753
699 1IM8 SAI 25
700 1KPH SAH 25.1082
701 3TLJ SAH 25.1082
702 4IWN GEK 25.7642
703 6ARJ BW4 25.974
704 6ARJ SAH 25.974
705 5DX8 SFG 25.974
706 5DXA SFG 25.974
707 5DWQ SFG 25.974
708 2PWY SAH 25.974
709 5DX1 SFG 25.974
710 5DX0 SFG 25.974
711 5WP5 SAH 26.2295
712 2GN4 NDP 26.2295
713 4AP3 NAP 26.2295
714 4AP3 FAD 26.2295
715 2GN4 UD1 26.2295
716 1RP0 AHZ 26.2295
717 4DSG FAD 26.2295
718 4DSG UDP 26.2295
719 3ICR FAD 26.2295
720 3ICS FAD 26.2295
721 3ICT FAD 26.2295
722 6CZ7 MGD 26.2295
723 2E5V FAD 26.2295
724 1M2K APR 26.2295
725 5YU3 NAD 26.2295
726 5YU3 PRO 26.2295
727 4GQB 0XU 27.2727
728 5HJM MTA 27.8689
729 3GDN HBX 27.8689
730 3GDN FAD 27.8689
731 5JCA FAD 27.8689
732 5JCA NDP 27.8689
733 4EUE NAI 27.8689
734 2GV8 FAD 27.8689
735 2GVC FAD 27.8689
736 1VQW FAD 27.8689
737 4M38 SAH 28.5714
738 1JG3 ADN 29.0043
739 1DL5 SAH 29.5082
740 1O97 AMP 29.5082
741 1O97 FAD 29.5082
742 3SQP FAD 29.5082
743 6DEN G8A 29.5082
744 6DEN TP9 29.5082
745 6DEN FAD 29.5082
746 2RH4 EMO 29.5082
747 2RGJ FAD 29.5082
748 1ZEM NAD 29.5082
749 1I8T FAD 29.5082
750 2NPX NAD 29.5082
751 2NPX FAD 29.5082
752 5GSN FAD 29.5082
753 5GSN NAP 29.5082
754 5FA5 MTA 30
755 1Z3C SA8 30.303
756 4OBW SAM 30.303
757 3VC1 SAH 30.303
758 3VC1 GST 30.303
759 4QTU SAM 31.1475
760 3FPZ AHZ 31.1475
761 1YQZ FAD 31.1475
762 2RAB NAD 31.1475
763 2RAB FAD 31.1475
764 1BDB NAD 31.1475
765 3LAD FAD 31.1475
766 2C31 ADP 31.1475
767 2C31 TZD 31.1475
768 2NYA MGD 31.1475
769 3A4T SFG 32.7869
770 2DKH 3HB 32.7869
771 2DKH FAD 32.7869
772 1JNR FAD 32.7869
773 4CNK FAD 32.7869
774 3OFK SAH 34.4262
775 3GFB NAD 34.4262
776 4IF4 BEF 34.4262
777 1EFV AMP 36.0656
778 1EFV FAD 36.0656
779 5U8U FAD 36.0656
780 5HXI FAD 37.7049
781 5HXI 5HN 37.7049
782 3GMB FAD 37.7049
783 4YRY NAD 39.3443
784 4YRY FAD 39.3443
785 5YEC ATP 45.9016
Pocket No.: 2; Query (leader) PDB : 6F5Z; Ligand: SAH; Similar sites found with APoc: 54
This union binding pocket(no: 2) in the query (biounit: 6f5z.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 1A69 FMB 2.5974
2 3KDM TES 3.4632
3 1Z34 2FD 3.8961
4 1XG5 NAP 4.329
5 1KTG AMP 4.34783
6 5GVR LMR 4.91803
7 1JJV ATP 4.91803
8 2VVG ADP 4.91803
9 1VHT BA3 4.91803
10 3BY9 SIN 4.91803
11 1VHW ADN 5.5336
12 5IFK HPA 5.62771
13 1HTW ADP 5.6962
14 6EV2 BGC 7.20721
15 5AOA PPI 8.19672
16 2QQF A1R 8.19672
17 5XHA FRU 8.19672
18 2F5X ASP 9.83607
19 2DFV NAD 9.83607
20 1DJN ADP 9.83607
21 5EZ7 FAD 9.83607
22 4RF2 NAP 10.3896
23 5MZI FAD 11.4754
24 5MZI FYK 11.4754
25 4P83 U5P 11.4754
26 1XVB BBX 11.4754
27 3OA2 NAD 11.4754
28 2Q4W FAD 11.4754
29 5F7J ADE 11.6883
30 5YKT PMP 13.1148
31 5ZZ6 ADP 13.1148
32 1LDN NAD 13.1148
33 3A4V PYR 13.1148
34 3A4V NAD 13.1148
35 3OJO NAD 13.1148
36 3EEL 53T 13.1148
37 3PNQ 2HA 14.7541
38 2WET FAD 14.7541
39 2WK1 SAH 14.7541
40 4NBW NAD 15.1515
41 1H2B NAJ 16.3934
42 3WDM ADN 16.4502
43 3IUY AMP 18.0328
44 1Z45 NAD 18.0328
45 1FWV SGA MAG FUC 21.3115
46 1OBB NAD 21.3115
47 1NVM NAD 22.9508
48 5OJ7 AR6 24.5902
49 4USI AKG 24.5902
50 1ODJ GMP 26.2295
51 4X7Y SAH 27.8689
52 1O94 ADP 29.5082
53 1WNB BTL 31.1475
54 2Y65 ADP 44.2623
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