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Receptor
PDB id Resolution Class Description Source Keywords
6CS8 1.75 Å NON-ENZYME: SIGNAL_HORMONE HIGH RESOLUTION CRYSTAL STRUCTURE OF FTSY-NG DOMAIN OF E. CO ESCHERICHIA COLI (STRAIN K12) COTRANSLATIONAL DELIVERY SRP PROTEIN TRANSPORT
Ref.: DISCOVERY OF FRAGMENTS THAT TARGET KEY INTERACTIONS SIGNAL RECOGNITION PARTICLE (SRP) AS POTENTIAL LEAD NEW CLASS OF ANTIBIOTICS. PLOS ONE V. 13 00387 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NA B:503;
Part of Protein;
none;
submit data
22.99 Na [Na+]
F9Y B:501;
B:502;
A:501;
A:502;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Kd ~ 100 uM
142.157 C9 H6 N2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6CS8 1.75 Å NON-ENZYME: SIGNAL_HORMONE HIGH RESOLUTION CRYSTAL STRUCTURE OF FTSY-NG DOMAIN OF E. CO ESCHERICHIA COLI (STRAIN K12) COTRANSLATIONAL DELIVERY SRP PROTEIN TRANSPORT
Ref.: DISCOVERY OF FRAGMENTS THAT TARGET KEY INTERACTIONS SIGNAL RECOGNITION PARTICLE (SRP) AS POTENTIAL LEAD NEW CLASS OF ANTIBIOTICS. PLOS ONE V. 13 00387 2018
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 5NIY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 6CS8 Kd ~ 100 uM F9Y C9 H6 N2 c1cc(cc2c1....
3 6FQD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 6DLX Kd ~ 480 uM GXY C8 H10 Br N O2 COc1cc(c(c....
5 6CVD Kd ~ 100 uM 4ME C10 H9 N O2 COC(=O)c1c....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 5NIY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 6CS8 Kd ~ 100 uM F9Y C9 H6 N2 c1cc(cc2c1....
3 6FQD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 6DLX Kd ~ 480 uM GXY C8 H10 Br N O2 COc1cc(c(c....
5 6CVD Kd ~ 100 uM 4ME C10 H9 N O2 COC(=O)c1c....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 2IYL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2Q9C - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 5L3W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 5NIY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 6CS8 Kd ~ 100 uM F9Y C9 H6 N2 c1cc(cc2c1....
6 6FQD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 6DLX Kd ~ 480 uM GXY C8 H10 Br N O2 COc1cc(c(c....
8 6CVD Kd ~ 100 uM 4ME C10 H9 N O2 COC(=O)c1c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: F9Y; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 F9Y 1 1
2 FK1 0.44186 0.681818
3 1F1 0.404255 0.6
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6CS8; Ligand: F9Y; Similar sites found with APoc: 48
This union binding pocket(no: 1) in the query (biounit: 6cs8.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 3KO0 TFP None
2 1TIQ COA 0.990099
3 1DNP FAD 1.65016
4 1NT4 G1P 1.9802
5 1XPM HMG 2.31023
6 1F0X FAD 2.64026
7 4RI1 ACO 3.22581
8 2QCX PF1 3.42205
9 1TO9 HMH 3.46154
10 2E9L PLM 3.63036
11 2E9L BGC 3.63036
12 2E9L OLA 3.63036
13 2H7C COA 3.63036
14 3HUJ AGH 3.82775
15 5HWO HMG 4.29043
16 5IKH 6BW 4.29043
17 3ZJ0 ACO 4.36893
18 3P9T TCL 4.56621
19 1BKJ FMN 4.58333
20 6ADI 9UO 4.62046
21 4BNU 9KQ 4.83271
22 5EHR 5OD 4.9505
23 3TMK T5A 5.09259
24 2FT0 ACO 5.53191
25 5VZ0 2BA 6.27063
26 2AAZ CB3 6.27063
27 4D8N 0HM 6.27803
28 2D3M COA 6.60066
29 5CYV WCA 6.93069
30 5KKA 6V0 6.93069
31 3H7U NAP 7.59076
32 4LH0 GLV 8.25082
33 3RMK BML 8.91089
34 2YOH WMJ 9.04762
35 4DRI RAP 9.18367
36 5JH2 A2P 9.24092
37 4UA3 COA 9.79381
38 2P8O BVA 9.92366
39 1QNF FAD 10.231
40 5IF4 6AK 10.6918
41 1ZTH ADP 12.0155
42 1ZP9 ATP 12.0155
43 1VBJ NAP 12.0996
44 1V0C KNC 16.3366
45 1V0C ACO 16.3366
46 2JEV NHQ 18.9655
47 2B4B COA 19.2982
48 4WO4 JLS 22.1122
Pocket No.: 2; Query (leader) PDB : 6CS8; Ligand: F9Y; Similar sites found with APoc: 262
This union binding pocket(no: 2) in the query (biounit: 6cs8.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 4M7V RAR None
2 1JQ9 PHE LEU SER TYR LYS None
3 5NNT DPV None
4 3GWL FAD None
5 5LJ0 6XX None
6 4K26 SFF 1.44928
7 5HGZ ACO 1.64609
8 6EKZ SNP 1.65016
9 5ZW7 FAD 1.65016
10 4OIV XX9 1.76991
11 4X7Y SAH 1.82482
12 3P0K FAD 1.8797
13 4KVX ACO 1.92308
14 4Y9J UCC 1.9802
15 4AUT FAD 1.9802
16 5OM2 DXT 1.9802
17 5W8Q BU4 1.9802
18 2WPX ACO 1.9802
19 6BA2 7KM 2.0339
20 2JBZ COA 2.0979
21 2B4Q NAP 2.17391
22 2FV5 541 2.29885
23 2VL8 UDP 2.31023
24 2VL8 CTS 2.31023
25 2R0N TGC 2.31023
26 3UA1 08Y 2.31023
27 4CDN FAD 2.31023
28 3PTQ NFG 2.31023
29 4LH7 NMN 2.31023
30 1OLM VTQ 2.31023
31 3LN0 52B 2.31023
32 1OKC CXT 2.3569
33 4LPG 1MV 2.4
34 5I3B HQE 2.43902
35 2XYQ SAH 2.45902
36 1WWZ ACO 2.51572
37 4OMJ 2TX 2.51799
38 1YQZ FAD 2.64026
39 1UDY FAD 2.64026
40 2X24 X24 2.64026
41 1UDY CS8 2.64026
42 3VZ3 NAP 2.64026
43 3UMV FAD 2.64026
44 6GAS FAD 2.64026
45 2WXD E18 2.64026
46 2P1C GG3 2.64026
47 2ZW5 COA 2.65781
48 4RPO T6C 2.69058
49 5LOF 70R 2.7027
50 6B2M COA 2.7972
51 4G6I RS3 2.85714
52 6AIX A3P 2.9703
53 2XXP DSL 2.9703
54 1E8G FAD 2.9703
55 1E8G FCR 2.9703
56 3Q8G PEE 2.9703
57 5G61 FNY 2.9703
58 5W6Y TRP 2.9703
59 4P53 NAI 2.9703
60 4QHP 32Q 2.9703
61 5DEP UD1 3.10078
62 4P8K 38C 3.125
63 4P8K FAD 3.125
64 6BR8 6OU 3.1746
65 6BR8 PGV 3.1746
66 5KTC FUH 3.19149
67 5KTC COA 3.19149
68 1VHT BA3 3.21101
69 4FC7 NAP 3.2491
70 4FC7 COA 3.2491
71 2UUU FAD 3.30033
72 2UUU PL3 3.30033
73 4PYW ACE THR THR ALA ILE NH2 3.30033
74 3C8Z 5CA 3.30033
75 2VAT COA 3.30033
76 1N20 3AG 3.30033
77 3QKD HI0 3.31492
78 6FTB M0E 3.33333
79 2GQT FAD 3.35821
80 1XSE NDP 3.38983
81 4UCC ZKW 3.43348
82 5EXA 5SO 3.47826
83 5UC9 MYR 3.53982
84 4Q86 AMP 3.63036
85 1HSK FAD 3.63036
86 3TDC 0EU 3.63036
87 1ATL 0QI 3.63036
88 4CJN QNZ 3.63036
89 3LDW ZOL 3.63036
90 5NDF LU2 3.63036
91 5NDF UDP 3.63036
92 4ZUL UN1 3.63036
93 5AZC PGT 3.66667
94 3ZLR X0B 3.79747
95 6CC0 EWM 3.79747
96 5F1R 42O 3.79747
97 1LQY BB2 3.80435
98 4U9W COA 3.86473
99 5O42 NAD 3.9604
100 5O42 9JW 3.9604
101 5O42 BGC 3.9604
102 1RM0 D6P 3.9604
103 3UR0 SVR 3.9604
104 3D9F N6C 3.9604
105 1W6U HXC 3.97351
106 4JE7 BB2 4.06091
107 6D6L FY4 4.11765
108 3VVY ET 4.12371
109 5XQL C2E 4.12371
110 1XAJ NAD 4.29043
111 1XAJ CRB 4.29043
112 1ZK7 FAD 4.29043
113 2FYF PLP 4.29043
114 4Z2B 4LC 4.29043
115 5CX6 CDP 4.29043
116 1RQJ RIS 4.34783
117 5MTE BB2 4.37956
118 2O3Z AI7 4.42804
119 5BQI 4UL 4.54545
120 5BQI GSH 4.54545
121 5V3Y 5V8 4.54545
122 1OPK P16 4.62046
123 3SDV 911 4.62046
124 3HVJ 705 4.62046
125 4EIL FOL 4.62046
126 3B6C SDN 4.62046
127 2FY3 CHT 4.62046
128 2E2P ADP 4.68227
129 5U83 ZN8 4.71698
130 4E1N TQX 4.81928
131 5FQK 6NT 4.83271
132 1FFU FAD 4.87805
133 4ONC 40B 4.92958
134 1V97 FAD 4.9505
135 5NE5 KIF 4.9505
136 4KCF AKM 4.9505
137 5ZBL AMP 4.9505
138 6AYI C3G 5.02513
139 4TWP AXI 5.16605
140 1OUK 084 5.28053
141 2XBK XBK 5.28053
142 6H8S FSZ 5.31561
143 1G27 BB1 5.35714
144 4XPL ACO 5.52147
145 4WKI 3PW 5.53191
146 3F5K CE5 5.61056
147 2BVL UDP 5.61056
148 2BVL GLC 5.61056
149 3KJS DQ1 5.61056
150 2FQX GMP 5.61056
151 2X5W K2B 5.61056
152 1EE0 CAA 5.61056
153 4BQO COA 5.61056
154 2J83 BAT 5.72519
155 4H07 IPH 5.84416
156 2Q4V ACO 5.88235
157 4RHP PEF 5.95745
158 2QIA U20 6.10687
159 2C9E DGD 6.27063
160 4C9G CXT 6.27063
161 4X1T UDP 6.27063
162 1IYK MYA 6.27063
163 1RM6 FAD 6.27063
164 4GFD 0YB 6.34146
165 3WR7 COA 6.47059
166 4JEM C5P 6.47059
167 4XRQ 1B0 6.49351
168 1D1G MTX 6.54762
169 4F4P 0SB 6.59341
170 2WSA MYA 6.60066
171 2WSA 646 6.60066
172 3KP6 SAL 6.62252
173 6EVN PRO PRO GLY PRO ALA GLY PRO PRO GLY 6.86275
174 3HRD FAD 6.875
175 1KUK PCA LYS TRP 6.89655
176 4XQC 13D 6.93069
177 2Q4W FAD 6.93069
178 4AIG FLX 6.96517
179 1F8Y 5MD 7.00637
180 3WHB DCC 7.2165
181 4ZOH FAD 7.26073
182 1IID NHM 7.26073
183 4WZ8 3W7 7.26073
184 1Q1R FAD 7.26073
185 1W5T ANP 7.26073
186 5TPR NAD 7.26073
187 5W99 A1V 7.26073
188 3CH6 NAP 7.34266
189 3CH6 311 7.34266
190 5O0B 9FE 7.40741
191 4IS0 1R4 7.46888
192 5N9T 8QQ 7.59076
193 1YUC EPH 7.84314
194 4C2X NHW 7.92079
195 1U70 MTX 8.06452
196 1U70 NDP 8.06452
197 1P0H COA 8.25082
198 1P0H ACO 8.25082
199 1DR1 NAP 8.46561
200 1DR1 HBI 8.46561
201 1T3Q FAD 8.92857
202 3Q2H QHF 9.09091
203 4F4S EFO 9.21053
204 1N62 FAD 9.24092
205 5LD8 6U5 9.24092
206 3G5K BB2 9.28962
207 1S7N COA 9.34066
208 4EJ1 FOL 9.43396
209 3K9U ACO 9.43396
210 5G3N X28 9.44882
211 5AE2 FAD 9.57096
212 5AE2 FYC 9.57096
213 4R57 ACO 9.65909
214 3QP8 HL0 9.78261
215 5Z1N PEF 10.119
216 4M4Q 21A 10.231
217 2GCN GDP 10.4478
218 3WDM ADN 10.728
219 6BYM HC3 10.8374
220 4IBF 1D5 10.8527
221 6AOV SIA GAL NAG GAL NAG 10.8911
222 3SE5 ANP 10.9756
223 2CNT COA 11.25
224 2JC9 ADN 11.5512
225 5EK3 5PK 12.2112
226 2YNC YNC 12.2112
227 5K04 COA 12.3529
228 1GUX ASP LEU TYR CYS TYR GLU GLN LEU ASN 12.5
229 5UQK U2F 12.5413
230 1PCA CIT 12.5413
231 2BL9 NDP 12.605
232 2BL9 CP6 12.605
233 5KAU RHQ 12.7273
234 2XSU PIE 13.4615
235 3H2B PPV 13.7931
236 5D9J 0N8 13.9037
237 5G5G FAD 15.1815
238 5MWE TCE 16.0494
239 3E3U NVC 16.7513
240 4QC6 30N 16.7598
241 1CMC SAM 17.3077
242 4EXS X8Z 17.6471
243 5ZCO PEK 17.8571
244 5Z84 PEK 17.8571
245 2DYR PEK 17.8571
246 5ZCO CHD 17.8571
247 5Z84 CHD 17.8571
248 2DYS TGL 17.8571
249 5Z84 TGL 17.8571
250 2DYR TGL 17.8571
251 5ZCO TGL 17.8571
252 5W97 CHD 17.8571
253 4LAE 1VM 17.9641
254 4LAE NAP 17.9641
255 2B4D COA 19.2982
256 3QUZ QUV 21.2121
257 3RUG DB6 21.2121
258 3SCM LGN 21.2121
259 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 21.2121
260 1NU4 MLA 26.8041
261 2Y69 CHD 28.5714
262 4V1T ADP 29.6875
Pocket No.: 3; Query (leader) PDB : 6CS8; Ligand: F9Y; Similar sites found with APoc: 573
This union binding pocket(no: 3) in the query (biounit: 6cs8.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 4R2I ANP None
2 5HCN GCP 1.14943
3 4U00 ADP 1.22951
4 3ITJ CIT 1.32013
5 1VKJ A3P 1.40351
6 5TSH ADP 1.65016
7 4P4T GDP 1.65016
8 5TSH ANP 1.65016
9 1I0B PEL 1.65016
10 3Q72 GNP 1.80723
11 1D2E GDP 1.9802
12 1TQ4 GDP 1.9802
13 2FSH ANP 1.9802
14 3WCZ CIT 1.9802
15 3E5H GNP 1.9802
16 3DKP ADP 2.04082
17 4AG5 ADP 2.31023
18 1Z6T ADP 2.31023
19 3G5S GSH 2.31023
20 4PFO ADP 2.31023
21 5Y6N ADP 2.31023
22 5M7P ADP 2.31023
23 5W7Q GDP 2.64026
24 4R43 GDP 2.64026
25 1DAR GDP 2.64026
26 1OS1 ATP 2.64026
27 1OS1 PYR 2.64026
28 2Q8M AMP 2.64026
29 3HYW DCQ 2.64026
30 1G6O ADP 2.72727
31 4DKX GDP 2.77778
32 2Y8E GNP 2.7933
33 2IL4 COA 2.91262
34 5YT0 GDP 2.9703
35 3COB ADP 2.9703
36 1BG2 ADP 2.9703
37 3DC4 ADP 2.9703
38 5BN3 ADP 2.9703
39 1WDT GTP 2.9703
40 1OYY AGS 2.9703
41 1SVK ALF GDP 2.9703
42 2OM2 GDP 2.9703
43 2QEN ADP 2.9703
44 1E2K TMC 2.9703
45 5E5U MLI 3.01508
46 4DDY DN6 3.04183
47 5UIV ADP 3.0837
48 1DAK ADP 3.125
49 1DAK DPU 3.125
50 1A8S PPI 3.2967
51 2OBM ADP 3.30033
52 4PPF FLC 3.30033
53 2XT3 ADP 3.30033
54 2ZFI ADP 3.30033
55 1XKV ATP 3.30033
56 2D7D ADP 3.30033
57 2ZPA ADP 3.30033
58 5VGR GDP 3.30033
59 3WXM GTP 3.30033
60 2WW4 ADP 3.30033
61 5I34 GDP 3.63036
62 1T5C ADP 3.63036
63 1V8K ANP 3.63036
64 3QDK QDK 3.63036
65 2GMV UN8 3.63036
66 1NHX FTB 3.63036
67 1P72 ADP 3.63036
68 2GMV PEP 3.63036
69 1NHX PEP 3.63036
70 5WRI A3P 3.63036
71 1WF3 GNP 3.65448
72 3WQM B29 3.65448
73 4IEE AGS 3.67347
74 4QOS ADP 3.77358
75 1R6N 434 3.79147
76 4LJ9 ACP 3.83481
77 1RYH GNP 3.94089
78 1JJV ATP 3.9604
79 5GOE GDP 3.9604
80 5H7K GDP 3.9604
81 2Q2Y ADP 3.9604
82 2Q2Y MKR 3.9604
83 2XAU ADP 3.9604
84 2X7I CIT 3.9604
85 1H65 GDP 4.07407
86 5W75 GDP 4.08163
87 1U0J ADP 4.11985
88 1B0U ATP 4.19847
89 2KIN ADP 4.20168
90 4NON GDP 4.23077
91 5KUT GDP 4.2328
92 5BQ5 ADP BEF 4.2328
93 4R98 GNH 4.29043
94 4DCT GDP 4.29043
95 4LYA ATP 4.29043
96 1SQ5 ADP 4.29043
97 2PL3 ADP 4.29043
98 3FKQ ATP 4.29043
99 2J5V PCA 4.29043
100 6FAA ADP 4.29043
101 6H5E ANP 4.29043
102 4NE2 ADP 4.29043
103 4NE2 SH2 4.29043
104 4IOK XPO 4.29043
105 3HU3 AGS 4.29448
106 5XKT GNP 4.5
107 1R0X ATP 4.54545
108 3ZFD ANP 4.5584
109 4G86 BNT 4.57746
110 2RCN GDP 4.62046
111 6A20 ADP 4.62046
112 1MKY GDP 4.62046
113 1QF5 GDP 4.62046
114 1QF5 RPL 4.62046
115 1R6B ADP 4.62046
116 4KVA GTP 4.62046
117 4HSE ADP 4.62046
118 5WC2 ADP 4.62046
119 3B7G ANP 4.62046
120 1IN4 ADP 4.62046
121 3VMF GTP 4.62046
122 2BIF ANP 4.62046
123 2BIF SIN 4.62046
124 2GJ8 ALF GDP 4.65116
125 1G6H ADP 4.66926
126 2OZE AGS 4.69799
127 4KFU ACP 4.71698
128 3KJI ADP 4.72441
129 3IUY AMP 4.82456
130 4M9Q GNP 4.84582
131 2CHG ANP 4.86726
132 5J1J ANP 4.91228
133 5YV5 ADP 4.9505
134 1SKQ GDP 4.9505
135 1YQT ADP 4.9505
136 5ZBR ANP 4.9505
137 6AU6 GDP 4.9505
138 1NST A3P 4.9505
139 1X6V ADP 4.9505
140 5K5Z ANP 4.9505
141 6FP4 E1T 4.9505
142 3CNL GNP 4.96183
143 2FNA ADP 5.04202
144 1F6B GDP 5.05051
145 5U32 GDP 5.08475
146 4XTR ADP 5.08475
147 4XTR ATP 5.08475
148 4XVU ATP 5.08475
149 2J0V GDP 5.18868
150 2D2F ADP 5.2
151 2WIC GNP 5.24345
152 3LRE ADP 5.28053
153 3EC1 GDP 5.28053
154 5W76 GDP 5.28053
155 2ZR9 DTP 5.28053
156 5LB3 ADP 5.28053
157 4KBF AMP 5.28053
158 2ZJ5 ADP 5.28053
159 1ZCB GDP 5.28053
160 1G7C 5GP 5.31915
161 4WOP CTP 5.33333
162 3DEF GDP 5.34351
163 2WOJ ADP ALF 5.36723
164 3A1S GDP 5.42636
165 6G14 G4P 5.44218
166 3IO3 ADP 5.45977
167 4TMZ GSP 5.50725
168 4WZ6 ATP 5.51724
169 2Y65 ADP 5.61056
170 5IRR GSP 5.61056
171 2W2X GSP 5.64516
172 1S8F GDP 5.64972
173 1M7G AV2 5.6872
174 1M7G ADX 5.6872
175 5JCP GDP ALF 5.72792
176 3BOS CDP 5.78512
177 3QXC ATP 5.78512
178 4FCW ADP 5.78778
179 2BEK ATP 5.83658
180 2WJG GDP 5.85106
181 1FP6 ADP 5.88235
182 5IFS ADP 5.90717
183 3MD0 GDP 5.94059
184 1F9V ADP 5.94059
185 1TAD ALF 5.94059
186 1TAD GDP 5.94059
187 1YTM ATP 5.94059
188 1LVK MNT BEF 5.94059
189 3AB4 THR 5.94059
190 1ZUI SKM 5.95238
191 2EFE GNH 5.99251
192 3T1O GDP 6.06061
193 1UAD GNP 6.06061
194 6AIC AMP 6.07477
195 3ZQ6 ADP ALF 6.17284
196 4U5X GNP 6.17978
197 3REF GDP 6.18557
198 3TK1 GDP 6.27063
199 2VVG ADP 6.27063
200 1GOJ ADP 6.27063
201 5M04 GDP 6.27063
202 5FG3 GDP 6.27063
203 1JI0 ATP 6.27063
204 1IWE IMP 6.27063
205 1XP8 AGS 6.27063
206 6B4K ANP 6.27063
207 3RC3 ANP 6.27063
208 4NCN GTP 6.27063
209 2C9O ADP 6.27063
210 2IXE ATP 6.27306
211 1RRC ADP 6.31229
212 1P9B GDP 6.33484
213 2FFQ GSP 6.43275
214 2CDN ADP 6.46766
215 1R2Q GNP 6.47059
216 1JJ7 ADP 6.53846
217 1BO4 COA 6.54762
218 3MJH GTP 6.54762
219 2GK6 ADP 6.60066
220 2IS6 ADP 6.60066
221 1OXV ANP 6.60066
222 4RD0 GDP 6.60066
223 4XGU ADP 6.60066
224 6CGN DA 6.60066
225 2WJH GDP 6.62651
226 2WJH FLC 6.62651
227 2CJW GDP 6.77083
228 3DOE GTP 6.77083
229 3H86 AP5 6.77083
230 3GJ4 GDP 6.78733
231 3GJ8 GDP 6.78733
232 3GJ5 GDP 6.78733
233 4CVN ADP 6.80628
234 1XX6 ADP 6.80628
235 3W5J GDP 6.86275
236 5OCG GNP 6.87831
237 3AB3 GDP 6.91057
238 3TBK ANP 6.93069
239 2A9K GDP 6.93069
240 2CE7 ADP 6.93069
241 1G41 ADP 6.93069
242 5KDO GDP 6.93069
243 1FQJ GDP 6.93069
244 2FAH GDP 6.93069
245 2FJU GSP 6.93069
246 1FQK GDP 6.93069
247 1GOT GDP 6.93069
248 1OFH ADP 6.93069
249 2NCD ADP 6.93069
250 1K6M AGS 6.93069
251 4QM7 GTP 7.01754
252 6CRK GDP 7.04225
253 1GP2 GDP 7.04225
254 2ZEJ GDP 7.06522
255 1LVG ADP 7.07071
256 5W7B MYR 7.0922
257 1CR1 TTP 7.09459
258 4KVG GTP 7.14286
259 4HDO GNP 7.18563
260 4HDQ GNP 7.18563
261 3X1Z GNP 7.18563
262 2OFW ADX 7.21154
263 3T5G GDP 7.23684
264 1KSH GDP 7.23684
265 1Z0K GTP 7.24638
266 4WZA ADP 7.26073
267 5KSZ GCP 7.26073
268 4WZA ACP 7.26073
269 1W5T ADP 7.26073
270 5Z69 AGS 7.26073
271 4YMU ATP 7.27273
272 2A5J GDP 7.32984
273 5TB5 GDP 7.33333
274 4V03 ADP 7.393
275 5TAR GDP 7.43243
276 4LPS GDP 7.43802
277 1ZJ6 G3D 7.48663
278 5NM7 GLY 7.5188
279 2BME GNP 7.52688
280 5LTJ ADP 7.59076
281 2WKQ GTP 7.59076
282 1W7J ADP BEF 7.59076
283 4ZKD GDP 7.59076
284 3Q9L ATP 7.69231
285 1NF3 GNP 7.69231
286 1Z2A GDP 7.7381
287 4E03 ADP 7.76699
288 4DID GDP 7.77202
289 3IIJ ADP 7.77778
290 2NGR GDP 7.8534
291 1A4R GNH 7.8534
292 1GRN GDP 7.8534
293 1A4R GDP 7.8534
294 2WMO GTP 7.89474
295 5GVR LMR 7.92079
296 1W0J ADP 7.92079
297 5AK0 8V1 7.92079
298 5HR5 ADP 7.92079
299 1W0J ADP BEF 7.92079
300 5UQW GDP 7.93651
301 1ZD9 GDP 7.97872
302 3SBD GNP 8.02139
303 5UPK GNP 8.10811
304 1YZQ GNP 8.23529
305 4P83 U5P 8.24176
306 2AWN ADP 8.25082
307 2HCJ GDP 8.25082
308 3U6B GDP 8.25082
309 4P3Y GDP 8.25082
310 3U6K GDP 8.25082
311 5JBQ GDP 8.25082
312 1D8T GDP 8.25082
313 4G5G GDP 8.25082
314 3FWY ADP 8.25082
315 2BVN GNP 8.25082
316 1LFD GNP 8.25082
317 2C5L GTP 8.25082
318 3DDC GNP 8.25082
319 2VB6 ADP BEF 8.25082
320 3Q85 GNP 8.28402
321 4YC7 GNP 8.28729
322 2PEZ GGZ 8.37989
323 2PEZ DAT 8.37989
324 5ZXD ATP 8.42491
325 3BFV ADP 8.48709
326 1CS4 GSP 8.49057
327 1KO8 6PG 8.57143
328 1KK1 GNP 8.58086
329 5H7J GCP 8.58086
330 1NSA BEN 8.58086
331 5WDR GNP 8.77193
332 2QZ4 ADP 8.77863
333 3T12 GDP ALF 8.82353
334 1Z08 GNP 8.82353
335 5UWO GNP 8.86076
336 5UWH GNP 8.86076
337 5DIF GNP 8.86076
338 5UWJ GNP 8.86076
339 5UWT GNP 8.86076
340 5UWI GNP 8.86076
341 6CIT GNP 8.86076
342 5DHF GNP 8.86076
343 5UWW GNP 8.86076
344 5UWQ GNP 8.86076
345 5UWR GNP 8.86076
346 5UWS GNP 8.86076
347 5UWP GNP 8.86076
348 5DI9 GNP 8.86076
349 1YVD GNP 8.87574
350 5O2T GSP 8.87574
351 3P4X ADP 8.91089
352 5MZN ADP 8.91089
353 5WLB GNP 9.03614
354 1WQ1 GDP 9.03614
355 1CLU DBG 9.03614
356 2UZI GTP 9.03614
357 1NVV GNP 9.03614
358 4BAS GNP 9.04523
359 2WHX ADP 9.06149
360 5LEF GTP 9.09091
361 4BQS K2Q 9.09091
362 4BQS ADP 9.09091
363 5ZB0 TYD 9.09091
364 5ZB0 ADP 9.09091
365 2ZTS ADP 9.16335
366 1SVI GDP 9.23077
367 1Y63 ADP 9.23913
368 3EZ2 ADP 9.24092
369 2O0J ADP 9.24092
370 5N69 ADP 9.24092
371 5MVR ADP 9.25926
372 3VX3 ADP 9.27419
373 4X8O AP5 9.34579
374 1Z0J GTP 9.41177
375 1EK0 GNP 9.41177
376 4V0K GDP 9.46746
377 3NHB ADP 9.47712
378 3GJ3 GDP 9.50226
379 3GJ0 GDP 9.50226
380 2XTZ GSP 9.57096
381 3KC1 2T6 9.57096
382 6D5E GNP 9.58084
383 6BVK GNP 9.58084
384 6BVM GNP 9.58084
385 6BVJ GNP 9.58084
386 6D5L GNP 9.58084
387 6D55 GNP 9.58084
388 6D5J GNP 9.58084
389 6D59 GNP 9.58084
390 6BVL GNP 9.58084
391 6BVI GNP 9.58084
392 6D5H GNP 9.58084
393 6D56 GNP 9.58084
394 6D5V GNP 9.58084
395 6D5G GNP 9.58084
396 6D5M GNP 9.58084
397 2PZE ATP 9.60699
398 5BXQ GDP 9.72222
399 3GJX GTP 9.72222
400 1IBR GNP 9.72222
401 4HAT GNP 9.72222
402 5G3Y ADP 9.73451
403 6FA4 GNP 9.82659
404 4RZ3 ADP 9.83051
405 2GDJ ANP 9.84848
406 4ITR GDP 9.90099
407 1NY5 ADP 9.90099
408 3A4M ADP 10
409 3WYF GTP 10.0457
410 1NRJ GTP 10.0917
411 1ZIN AP5 10.1382
412 4J0Q GDP 10.231
413 2C77 GNP 10.231
414 2C78 GNP 10.231
415 4HE2 AMP 10.231
416 3BC1 GNP 10.2564
417 2CK3 ANP 10.274
418 2CK3 ADP 10.274
419 3B5J 12D 10.2881
420 5G41 AP5 10.3139
421 1XPJ TLA 10.3175
422 3BD9 A3P 10.3571
423 2GCO GNP 10.4478
424 3UIE ANP 10.5
425 4H1V GNP 10.5611
426 2GKS ADP 10.5611
427 1G7S GDP 10.5611
428 4MKF AP5 10.5991
429 2V7Q ADP 10.6061
430 2V7Q ATP 10.6061
431 43CA NPO 10.6195
432 4YJ1 ADP 10.8911
433 5FTB ANP 10.8911
434 5OEC GDP 10.929
435 2CBZ ATP 10.9705
436 4MKG AP5 11.0599
437 5IRN ADP 11.2211
438 1TU3 GNP 11.3924
439 4NU0 AP5 11.5207
440 5XDR ADP 11.5512
441 5KSP GDP 11.5789
442 2X77 GDP 11.6402
443 1UPT GTP 11.6667
444 1YZG GDP 11.7318
445 3PQC GDP 11.7949
446 5EE5 GTP 11.8812
447 1WA5 GTP 11.9318
448 4PC3 GDP 12.0567
449 3KTA AP5 12.0879
450 1M2O GNP 12.1053
451 2DPY ADP 12.2112
452 4B47 GDP 12.2112
453 5H67 ATP 12.5
454 3T34 GDP 12.5413
455 4TTQ ATP 12.5581
456 1IHU AF3 12.8713
457 1IHU ADP 12.8713
458 6C90 ADP 12.8713
459 5H4S RAM 13.0282
460 5TCI MLI 13.0435
461 4D81 ADP 13.0742
462 1GXU 2HP 13.1868
463 3ZIA ATP 13.2013
464 3ZIA ADP 13.2013
465 1B7T ADP 13.4615
466 3KUD GDP 13.5802
467 1GUA GNP 13.5802
468 4V1F BQ1 13.9535
469 3EWA ANP 13.9752
470 4YDS ATP 14.0351
471 5J1S ATP 14.0845
472 4IHQ ADP 14.1914
473 2EW1 GNP 14.4279
474 4WBD CIT 14.8515
475 1KK8 BEF ADP 15.1079
476 6DEF GCP 15.1815
477 3WY9 GDP 15.5116
478 3WYA GDP 15.5116
479 2ODE ALF GDP 15.6028
480 5MZI FYK 15.8416
481 5XC5 GTP 15.9091
482 2HT6 GDP 16.092
483 2QTV GNP 16.3265
484 3CX8 GSP 17.2414
485 2I4I AMP 17.4917
486 2XTN GTP 17.5214
487 4ZNL BEF ADP 17.8832
488 3BER AMP 18.0723
489 4PX9 ADP 18.1507
490 1XMV ADP 18.1518
491 3GJ7 GDP 18.3673
492 1HTW ADP 18.9873
493 3AQ4 GDP 19.5652
494 5E95 GDP 19.5876
495 2BCG GDP 19.9029
496 2HF9 GSP 19.9115
497 4BFW ZVW 20.132
498 1J2J GTP 20.4819
499 1O3Y GTP 20.4819
500 2J59 GTP 20.4819
501 1RE0 GDP 21.3415
502 1S9D GDP 21.3415
503 4YS0 ADP 21.4521
504 3CPJ GDP 21.5247
505 4ZI2 GNP 21.5789
506 1YZN GNP 21.6216
507 4GOJ GNP 21.6931
508 1VG0 GDP 21.7391
509 1VG8 GNP 21.7391
510 1OW3 GDP 21.7617
511 1R4A GNP 21.8182
512 5SZH GNP 22.1675
513 4KAX GTP 22.4852
514 5IRC GDP 22.5806
515 2F9L GDP 22.6131
516 5HPY GDP 22.7027
517 1KMQ GNP 22.8261
518 3TKL GTP 22.9592
519 2W83 GTP 23.0303
520 5O74 GDP 23.3333
521 4XOI GTP 23.3333
522 4XSH GSP 23.4637
523 4HI0 GDP 23.6181
524 1TX4 ALF GDP 23.7288
525 5DI3 GNP 23.7838
526 3RWO GDP 23.7838
527 1NJF ADP 24
528 1NJF AGS 24
529 3NKV GNP 24
530 3QF7 ANP 24
531 3N5C GDP 24.0741
532 3SFV GDP 24.3094
533 1VG9 GDP 24.3243
534 1VG1 GDP 24.3243
535 1KY3 GDP 24.7253
536 4D0N GDP 24.8649
537 3LXR GDP 24.8649
538 6BC0 GSP 24.8649
539 6BCB GSP 24.8649
540 6BCA GSP 24.8649
541 5Z2M GTP 25
542 1YRB GDP 25.1908
543 1CXZ GSP 25.2747
544 4YLG GDP 25.4335
545 4JLV ADP 25.6506
546 4LC1 GDP 26.0726
547 3ZS9 ADP ALF 26.3158
548 3H4S ADP 26.7327
549 4FRZ ADP 26.7327
550 2QN6 GDP 26.8817
551 2D7C GTP 26.9461
552 2A5F GTP 27.4286
553 3WYG GTP 27.6316
554 1UKZ ADP 28.0788
555 2G77 GDP 28.2828
556 2W58 ADP 28.7129
557 3RAB GNP 29.5858
558 1Z06 GNP 29.6296
559 3QBT GNP 33.3333
560 4LHW GNP 33.3333
561 3TNF GNP 33.3333
562 1Z0A GDP 34.4828
563 1D5C GDP 34.5679
564 3PCR GTP 35.1852
565 1OIX GDP 37.6963
566 1OIV GDP 38.2199
567 5JCZ GDP 40.7821
568 4LX0 BEF GDP 41.2429
569 2HV8 GTP 41.8605
570 1Z0F GDP 41.8994
571 4C4P GNP 42.1965
572 4D0G GTP 42.2857
573 3KPE TM3 43.5897
574 5UWU GNP 50
Pocket No.: 4; Query (leader) PDB : 6CS8; Ligand: F9Y; Similar sites found with APoc: 48
This union binding pocket(no: 4) in the query (biounit: 6cs8.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 3X1M COA None
2 3WXB NDP 2.15054
3 4ZDJ UTP 2.64026
4 6BMS POV 2.64026
5 4I90 CHT 2.9703
6 2VZZ SCA 3.21101
7 1FL2 FAD 3.30033
8 3L9R L9Q 3.53357
9 1Z83 AP5 3.57143
10 1QF9 C5P 3.60825
11 1QF9 ADP 3.60825
12 1QF9 ALF 3.60825
13 6EK3 OUL 3.61991
14 5WRJ A3P 3.63036
15 1OAA OAA 3.861
16 5CKS GAL 3.9604
17 5BYK OAQ 4.2471
18 5BYK A3P 4.2471
19 3AYI HCI 4.29043
20 3AYI FAD 4.29043
21 4IOK ADP 4.29043
22 5L4S NAP 4.29043
23 5L4S 6KX 4.29043
24 5OSW DIU 4.62046
25 4IA6 EIC 4.62046
26 6B8B ADP 4.81928
27 4EUE NAI 4.9505
28 4JZ8 CIT 5.61056
29 4OHY ANP 5.94059
30 5WL1 CUY 6
31 5WL1 D3D 6
32 1NN5 2DT 6.04651
33 1NN5 ANP 6.04651
34 5XWV 8H6 6.85484
35 2WOR 2AN 7
36 3V2U ATP 7.26073
37 4XCP PLM 7.64706
38 5WQP NAP 8.11966
39 3RLF ANP 8.25082
40 1AKY AP5 8.63636
41 5LXT 7AK 9.09091
42 5LXT GDP 9.09091
43 1N5D NDP 9.375
44 1PFK ADP 10.231
45 1S3G AP5 11.0599
46 2JHP GUN 11.8812
47 5O98 NAP 16.1716
48 1DTL BEP 26.7081
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