Receptor
PDB id Resolution Class Description Source Keywords
6CBG 2 Å EC: 5.3.2.1 MACROPHAGE MIGRATION INHIBITORY FACTOR IN COMPLEX WITH A PYR INHIBITOR (5) HOMO SAPIENS INHIBITOR COMPLEX CYTOKINE
Ref.: OPTIMIZATION OF PYRAZOLES AS PHENOL SURROGATES TO Y POTENT INHIBITORS OF MACROPHAGE MIGRATION INHIBITOR CHEMMEDCHEM V. 13 1092 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 C:203;
B:202;
C:201;
B:203;
A:201;
C:202;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
 submit data
96.063 O4 S [O-]S...
GOL B:205;
C:205;
A:205;
C:207;
B:201;
A:202;
C:206;
A:204;
A:203;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
EWG C:204;
B:204;
 Valid;
Valid;
 none;
none;
 Ki = 113 uM
188.183 C10 H8 N2 O2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3L5R 1.94 Å EC: 5.3.2.1 CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR PHENYLCHROMENONE INHIBITOR AT 1.94A RESOLUTION HOMO SAPIENS PROTEIN-LIGAND COMPLEX CYTOKINE CYTOPLASM IMMUNE RESPONSEINFLAMMATORY RESPONSE INNATE IMMUNITY ISOMERASE PHOSPHOPSECRETED ACETYLATION
Ref.: FRAGMENT SCREENING OF INHIBITORS FOR MIF TAUTOMERAS A CRYPTIC SURFACE BINDING SITE. BIOORG.MED.CHEM.LETT. V. 20 1821 2010
Members (27)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1LJT ic50 = 7 uM HDI C12 H13 N O4 COC(=O)C[C....
2 3L5R ic50 = 38 nM 47X C15 H10 O5 c1cc(c(cc1....
3 5J7Q Ki = 26.6 uM 6H2 C13 H10 N2 O2 c1ccn2cc(n....
4 5HVT Kd = 0.055 uM NVS C15 H13 N O4 COc1ccc(cc....
5 5B4O - 6DQ C13 H8 N2 O S c1ccc2c(c1....
6 1GCZ Ki = 7.4 uM YZ9 C12 H10 O5 CCOC(=O)C1....
7 3L5P - 428 C9 H11 N3 O CC(C)c1cn2....
8 5HVS Kd = 0.071 uM 65V C24 H15 F N4 O4 c1cc(cc(c1....
9 6B1C Kd = 0.111 uM C9J C17 H12 F N5 O2 CN1C=Cc2cc....
10 3L5T - 956 C20 H18 N4 O2 S CN1c2ccccc....
11 3IJJ - EN1 C9 H8 O4 c1cc(ccc1/....
12 6CBG Ki = 113 uM EWG C10 H8 N2 O2 c1cc(cc(c1....
13 4K9G - 1Q1 C12 H12 F N O3 CC(=O)C[C@....
14 3IJG Kd = 54 uM AVR C13 H17 N3 O C[C@H](C(=....
15 4WRB Ki = 0.65 uM 3TW C20 H18 N4 O3 COCCOc1ccc....
16 1CA7 - ENO C9 H8 O4 c1cc(ccc1C....
17 2OOH ic50 = 1.3 uM OX3 C14 H17 N O3 c1cc(ccc1C....
18 2OOZ ic50 = 7 uM OX5 C13 H17 N O3 CC(C)(C)CC....
19 3DJI - 3E1 C16 H16 N2 O4 CC(=O)Nc1c....
20 6CBF Ki = 6.8 uM EWD C16 H12 N2 O3 c1ccc(cc1)....
21 3L5U - ZEC C7 H6 N2 O3 S2 c1cc2c(cc1....
22 6CB5 Ki = 4.3 uM EV7 C20 H14 N2 O3 c1ccc2cc(c....
23 6B1K Kd = 0.213 uM C9G C17 H13 N5 O2 CN1C=Cc2cc....
24 3L5S - 88X C15 H13 N3 O2 CCC1=CC(=O....
25 6CBH Ki = 0.51 uM EWJ C20 H13 F N2 O3 c1ccc2cc(c....
26 3U18 ic50 = 0.81 uM Y0X C34 H28 N6 O16 S4 COc1c(ccc(....
27 6B2C Kd = 0.094 uM C9Y C18 H12 F N5 O4 c1cc(c(cc1....
70% Homology Family (28)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1LJT ic50 = 7 uM HDI C12 H13 N O4 COC(=O)C[C....
2 3L5R ic50 = 38 nM 47X C15 H10 O5 c1cc(c(cc1....
3 5J7Q Ki = 26.6 uM 6H2 C13 H10 N2 O2 c1ccn2cc(n....
4 5HVT Kd = 0.055 uM NVS C15 H13 N O4 COc1ccc(cc....
5 5B4O - 6DQ C13 H8 N2 O S c1ccc2c(c1....
6 1GCZ Ki = 7.4 uM YZ9 C12 H10 O5 CCOC(=O)C1....
7 3L5P - 428 C9 H11 N3 O CC(C)c1cn2....
8 5HVS Kd = 0.071 uM 65V C24 H15 F N4 O4 c1cc(cc(c1....
9 6B1C Kd = 0.111 uM C9J C17 H12 F N5 O2 CN1C=Cc2cc....
10 3L5T - 956 C20 H18 N4 O2 S CN1c2ccccc....
11 3IJJ - EN1 C9 H8 O4 c1cc(ccc1/....
12 6CBG Ki = 113 uM EWG C10 H8 N2 O2 c1cc(cc(c1....
13 4K9G - 1Q1 C12 H12 F N O3 CC(=O)C[C@....
14 3IJG Kd = 54 uM AVR C13 H17 N3 O C[C@H](C(=....
15 4WRB Ki = 0.65 uM 3TW C20 H18 N4 O3 COCCOc1ccc....
16 1CA7 - ENO C9 H8 O4 c1cc(ccc1C....
17 2OOH ic50 = 1.3 uM OX3 C14 H17 N O3 c1cc(ccc1C....
18 2OOZ ic50 = 7 uM OX5 C13 H17 N O3 CC(C)(C)CC....
19 3DJI - 3E1 C16 H16 N2 O4 CC(=O)Nc1c....
20 6CBF Ki = 6.8 uM EWD C16 H12 N2 O3 c1ccc(cc1)....
21 3L5U - ZEC C7 H6 N2 O3 S2 c1cc2c(cc1....
22 6CB5 Ki = 4.3 uM EV7 C20 H14 N2 O3 c1ccc2cc(c....
23 6B1K Kd = 0.213 uM C9G C17 H13 N5 O2 CN1C=Cc2cc....
24 3L5S - 88X C15 H13 N3 O2 CCC1=CC(=O....
25 6CBH Ki = 0.51 uM EWJ C20 H13 F N2 O3 c1ccc2cc(c....
26 3U18 ic50 = 0.81 uM Y0X C34 H28 N6 O16 S4 COc1c(ccc(....
27 6B2C Kd = 0.094 uM C9Y C18 H12 F N5 O4 c1cc(c(cc1....
28 1MFI Ki = 2.6 uM FHC C9 H6 F O3 c1cc(ccc1C....
50% Homology Family (32)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1LJT ic50 = 7 uM HDI C12 H13 N O4 COC(=O)C[C....
2 3L5R ic50 = 38 nM 47X C15 H10 O5 c1cc(c(cc1....
3 5J7Q Ki = 26.6 uM 6H2 C13 H10 N2 O2 c1ccn2cc(n....
4 5HVT Kd = 0.055 uM NVS C15 H13 N O4 COc1ccc(cc....
5 5B4O - 6DQ C13 H8 N2 O S c1ccc2c(c1....
6 1GCZ Ki = 7.4 uM YZ9 C12 H10 O5 CCOC(=O)C1....
7 3L5P - 428 C9 H11 N3 O CC(C)c1cn2....
8 5HVS Kd = 0.071 uM 65V C24 H15 F N4 O4 c1cc(cc(c1....
9 6B1C Kd = 0.111 uM C9J C17 H12 F N5 O2 CN1C=Cc2cc....
10 3L5T - 956 C20 H18 N4 O2 S CN1c2ccccc....
11 3IJJ - EN1 C9 H8 O4 c1cc(ccc1/....
12 6CBG Ki = 113 uM EWG C10 H8 N2 O2 c1cc(cc(c1....
13 4K9G - 1Q1 C12 H12 F N O3 CC(=O)C[C@....
14 3IJG Kd = 54 uM AVR C13 H17 N3 O C[C@H](C(=....
15 4WRB Ki = 0.65 uM 3TW C20 H18 N4 O3 COCCOc1ccc....
16 1CA7 - ENO C9 H8 O4 c1cc(ccc1C....
17 2OOH ic50 = 1.3 uM OX3 C14 H17 N O3 c1cc(ccc1C....
18 2OOZ ic50 = 7 uM OX5 C13 H17 N O3 CC(C)(C)CC....
19 3DJI - 3E1 C16 H16 N2 O4 CC(=O)Nc1c....
20 6CBF Ki = 6.8 uM EWD C16 H12 N2 O3 c1ccc(cc1)....
21 3L5U - ZEC C7 H6 N2 O3 S2 c1cc2c(cc1....
22 6CB5 Ki = 4.3 uM EV7 C20 H14 N2 O3 c1ccc2cc(c....
23 6B1K Kd = 0.213 uM C9G C17 H13 N5 O2 CN1C=Cc2cc....
24 3L5S - 88X C15 H13 N3 O2 CCC1=CC(=O....
25 6CBH Ki = 0.51 uM EWJ C20 H13 F N2 O3 c1ccc2cc(c....
26 3U18 ic50 = 0.81 uM Y0X C34 H28 N6 O16 S4 COc1c(ccc(....
27 6B2C Kd = 0.094 uM C9Y C18 H12 F N5 O4 c1cc(c(cc1....
28 4Q3F - TLA C4 H6 O6 [C@@H]([C@....
29 6C5F Ki = 33 uM 7L9 C14 H9 N O6 c1cc(cc(c1....
30 3RF5 Ki = 2.37 uM FUZ C12 H11 N O3 c1ccc(c(c1....
31 3RF4 Ki = 0.56 uM FUN C12 H11 Cl N2 O5 S c1cc(oc1)C....
32 1MFI Ki = 2.6 uM FHC C9 H6 F O3 c1cc(ccc1C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: EWG; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 EWG 1 1
2 Q2S 0.457627 0.677419
3 V7V 0.45 0.756757
4 L43 0.45 0.756757
5 5F5 0.403509 0.606061
6 EWD 0.402985 0.756757
Similar Ligands (3D)
Ligand no: 1; Ligand: EWG; Similar ligands found: 631
No: Ligand Similarity coefficient
1 LEL 1.0000
2 VM1 0.9988
3 AVA 0.9897
4 5F8 0.9847
5 5FL 0.9823
6 5TZ 0.9716
7 U7E 0.9706
8 RKV 0.9680
9 363 0.9607
10 78Y 0.9577
11 49P 0.9577
12 LFQ 0.9563
13 0LO 0.9544
14 M5H 0.9544
15 LL1 0.9542
16 K48 0.9517
17 7O4 0.9492
18 R20 0.9459
19 IQ5 0.9432
20 WVV 0.9429
21 5E5 0.9421
22 BIK 0.9412
23 2GQ 0.9407
24 6MW 0.9406
25 AUV 0.9394
26 XI7 0.9388
27 BZJ 0.9382
28 G14 0.9373
29 HQJ 0.9371
30 DXK 0.9369
31 ZZA 0.9365
32 9UL 0.9359
33 2D2 0.9351
34 2UZ 0.9341
35 TCR 0.9339
36 QR2 0.9337
37 L5V 0.9335
38 AMR 0.9333
39 4FF 0.9323
40 D2G 0.9319
41 L1T 0.9305
42 MZM 0.9300
43 DRG 0.9297
44 ODK 0.9293
45 60L 0.9285
46 MNP 0.9285
47 IQQ 0.9284
48 D3G 0.9277
49 SSY 0.9271
50 7L4 0.9261
51 XDK 0.9255
52 1FE 0.9252
53 795 0.9250
54 3VQ 0.9229
55 D1G 0.9229
56 4V2 0.9228
57 II4 0.9228
58 4AU 0.9228
59 GZ2 0.9223
60 P4L 0.9222
61 4I8 0.9219
62 PDC 0.9215
63 344 0.9213
64 I2E 0.9209
65 FCD 0.9206
66 JCZ 0.9201
67 C2Y 0.9200
68 ZME 0.9199
69 C82 0.9196
70 QMS 0.9194
71 0F9 0.9192
72 IOS 0.9187
73 PUE 0.9186
74 6TZ 0.9185
75 PD2 0.9182
76 L22 0.9178
77 F40 0.9178
78 8NX 0.9177
79 CKA 0.9176
80 7I2 0.9174
81 M3E 0.9171
82 92P 0.9171
83 ONR 0.9171
84 AY4 0.9169
85 HA5 0.9168
86 L5D 0.9167
87 GO2 0.9166
88 CH9 0.9161
89 1A7 0.9156
90 BZE 0.9155
91 7ZL 0.9154
92 GNV 0.9153
93 0UL 0.9152
94 6C8 0.9152
95 VBC 0.9149
96 JTA 0.9148
97 QIV 0.9148
98 LDR 0.9143
99 IAC 0.9142
100 1VK 0.9141
101 463 0.9138
102 IOP 0.9136
103 A6W 0.9132
104 5P3 0.9132
105 TRP 0.9132
106 RD4 0.9130
107 PIQ 0.9130
108 DNF 0.9130
109 X6P 0.9128
110 7MW 0.9127
111 PEY 0.9124
112 Q4G 0.9121
113 JBZ 0.9121
114 VXX 0.9120
115 CSN 0.9120
116 0NX 0.9120
117 4BL 0.9119
118 9AP 0.9117
119 BZQ 0.9113
120 YE7 0.9108
121 6KT 0.9108
122 JP2 0.9106
123 5B2 0.9105
124 KLE 0.9104
125 LTN 0.9104
126 9FE 0.9103
127 M4E 0.9103
128 AZM 0.9102
129 RVE 0.9098
130 5C1 0.9097
131 JMG 0.9097
132 TT4 0.9097
133 94W 0.9094
134 492 0.9090
135 2LY 0.9089
136 5H6 0.9087
137 YE6 0.9086
138 4BY 0.9085
139 22L 0.9081
140 CWJ 0.9079
141 E1T 0.9078
142 1ER 0.9075
143 JSX 0.9074
144 X48 0.9071
145 8G0 0.9071
146 X6W 0.9069
147 BPY 0.9067
148 M1Z 0.9067
149 NIR 0.9065
150 S1D 0.9065
151 JDN 0.9062
152 4TU 0.9058
153 A5H 0.9057
154 AJ1 0.9054
155 V2Z 0.9054
156 2JX 0.9053
157 3ZB 0.9051
158 4G2 0.9048
159 2O6 0.9047
160 3VX 0.9047
161 C0W 0.9046
162 MD6 0.9044
163 IWT 0.9043
164 55D 0.9041
165 SSC 0.9040
166 2F6 0.9040
167 SLS 0.9039
168 1QP 0.9038
169 EV2 0.9035
170 A9B 0.9033
171 VFG 0.9031
172 30G 0.9031
173 P9I 0.9030
174 TIA 0.9029
175 BGU 0.9028
176 54X 0.9027
177 C9E 0.9025
178 XCG 0.9023
179 4Z9 0.9022
180 LZ5 0.9022
181 BP7 0.9020
182 3C5 0.9019
183 ANC 0.9017
184 NK5 0.9015
185 M6Z 0.9015
186 CXH 0.9014
187 0DF 0.9014
188 3GX 0.9011
189 S60 0.9009
190 NFZ 0.9009
191 KCH 0.9005
192 9BF 0.9005
193 0JD 0.9004
194 5GT 0.9002
195 6DP 0.9002
196 5LD 0.9001
197 5V7 0.8999
198 M78 0.8995
199 0HO 0.8994
200 UNJ 0.8994
201 JR2 0.8993
202 P80 0.8993
203 1SF 0.8993
204 3IL 0.8992
205 1F1 0.8992
206 657 0.8991
207 2HU 0.8988
208 CK2 0.8988
209 N91 0.8987
210 OW7 0.8987
211 NAG 0.8986
212 HLD 0.8985
213 549 0.8983
214 5NI 0.8983
215 5NN 0.8982
216 12T 0.8981
217 TMG 0.8981
218 8G6 0.8981
219 6J9 0.8978
220 8NB 0.8976
221 6QF 0.8975
222 S0E 0.8975
223 ABI 0.8974
224 3A9 0.8973
225 RA7 0.8972
226 6NI 0.8969
227 6FB 0.8968
228 GNJ 0.8965
229 9CE 0.8965
230 KF5 0.8963
231 N3W 0.8963
232 NDG 0.8962
233 HH6 0.8960
234 6NT 0.8958
235 FC2 0.8955
236 692 0.8955
237 0W1 0.8954
238 36M 0.8953
239 2ZM 0.8951
240 5TO 0.8950
241 JAW 0.8950
242 2QU 0.8950
243 MS0 0.8949
244 ANF 0.8946
245 9JT 0.8945
246 FER 0.8945
247 WUB 0.8945
248 MPV 0.8943
249 VFM 0.8942
250 15N 0.8941
251 4GU 0.8940
252 YTX 0.8940
253 SRO 0.8938
254 7MX 0.8935
255 V1T 0.8934
256 3QV 0.8934
257 2JK 0.8931
258 1AJ 0.8930
259 OA1 0.8930
260 GNY 0.8930
261 DNC 0.8929
262 KYA 0.8928
263 OVM 0.8927
264 Y3L 0.8926
265 8WZ 0.8926
266 0HN 0.8925
267 FTV 0.8924
268 S7S 0.8922
269 1HN 0.8921
270 5DL 0.8921
271 3MB 0.8920
272 LR2 0.8920
273 FF2 0.8919
274 X0W 0.8916
275 61M 0.8916
276 BBY 0.8915
277 3R4 0.8915
278 3J8 0.8913
279 GJP 0.8913
280 68A 0.8912
281 L03 0.8910
282 8XL 0.8910
283 SKF 0.8910
284 7FF 0.8909
285 0GZ 0.8909
286 1L5 0.8907
287 N7I 0.8906
288 3VW 0.8906
289 NLA 0.8906
290 TSS 0.8905
291 M4N 0.8904
292 AA 0.8902
293 MAJ 0.8901
294 NPA 0.8901
295 1X8 0.8901
296 BVS 0.8901
297 PJW 0.8900
298 A29 0.8899
299 9FL 0.8898
300 HJH 0.8894
301 NLQ 0.8890
302 36Z 0.8889
303 6R8 0.8888
304 F31 0.8888
305 CKU 0.8888
306 MB1 0.8888
307 HA6 0.8888
308 FQX 0.8887
309 1FL 0.8885
310 5VL 0.8885
311 9CA 0.8885
312 BQ2 0.8885
313 0OL 0.8883
314 1IT 0.8882
315 8D6 0.8881
316 P9E 0.8880
317 2FX 0.8878
318 YZ9 0.8877
319 VFJ 0.8877
320 BPU 0.8873
321 RSV 0.8873
322 4ME 0.8872
323 6FG 0.8871
324 F2W 0.8870
325 28A 0.8870
326 2UD 0.8870
327 THA 0.8869
328 3Y7 0.8869
329 1V3 0.8868
330 GF4 0.8868
331 4XF 0.8867
332 XFE 0.8866
333 3NY 0.8866
334 B41 0.8863
335 833 0.8863
336 DI9 0.8863
337 0FR 0.8860
338 DDU 0.8853
339 B2T 0.8851
340 2HC 0.8850
341 J9N 0.8849
342 97T 0.8849
343 1V4 0.8849
344 JF5 0.8849
345 A73 0.8848
346 X11 0.8846
347 878 0.8845
348 KW8 0.8844
349 8HC 0.8844
350 6C9 0.8844
351 CNI 0.8843
352 8CC 0.8842
353 P93 0.8842
354 OKM 0.8841
355 BL0 0.8840
356 ZEA 0.8840
357 X0U 0.8840
358 PRZ 0.8838
359 5OO 0.8838
360 J9Q 0.8837
361 4RU 0.8837
362 FWD 0.8837
363 GJK 0.8836
364 EUE 0.8836
365 KMY 0.8833
366 428 0.8830
367 BK9 0.8830
368 ESX 0.8828
369 3D8 0.8828
370 0FK 0.8827
371 0SY 0.8825
372 9ZE 0.8825
373 C4E 0.8823
374 DHC 0.8822
375 5TY 0.8821
376 R8Y 0.8820
377 JG8 0.8820
378 P7Y 0.8820
379 ZON 0.8820
380 B21 0.8818
381 KTW 0.8818
382 S3P 0.8816
383 PRL 0.8816
384 OW4 0.8816
385 DK1 0.8815
386 ISC 0.8815
387 ZIQ 0.8813
388 JWS 0.8813
389 AN3 0.8811
390 QUS 0.8810
391 1XS 0.8810
392 CX4 0.8808
393 EN1 0.8808
394 ITE 0.8807
395 5WN 0.8806
396 HX4 0.8806
397 GNR 0.8806
398 ESI 0.8806
399 ENO 0.8805
400 J38 0.8804
401 7VP 0.8803
402 TXW 0.8803
403 X2M 0.8802
404 MMJ 0.8802
405 NKI 0.8802
406 WLH 0.8800
407 CFA 0.8800
408 UN3 0.8800
409 H5B 0.8798
410 25F 0.8798
411 EVO 0.8797
412 6C5 0.8796
413 J9T 0.8796
414 KDG 0.8794
415 6DQ 0.8793
416 THM 0.8791
417 B4O 0.8791
418 AX3 0.8791
419 67Y 0.8790
420 CWD 0.8790
421 F12 0.8788
422 EQA 0.8784
423 1V1 0.8783
424 PRO GLY 0.8781
425 8WO 0.8781
426 ISJ 0.8779
427 ZRK 0.8776
428 78U 0.8776
429 JB8 0.8775
430 FDR 0.8771
431 7WR 0.8770
432 6C4 0.8769
433 YZM 0.8768
434 5OF 0.8767
435 OVP 0.8767
436 TZM 0.8766
437 20D 0.8765
438 3SU 0.8765
439 B1J 0.8762
440 TYL 0.8762
441 MUR 0.8762
442 BSA 0.8761
443 MXD 0.8760
444 4KL 0.8759
445 OQC 0.8757
446 LJ3 0.8757
447 PZX 0.8755
448 2P3 0.8755
449 5XC 0.8754
450 U4J 0.8753
451 DTR 0.8752
452 3R6 0.8751
453 069 0.8750
454 AJY 0.8750
455 67X 0.8749
456 DG2 0.8749
457 774 0.8748
458 HRM 0.8746
459 EXD 0.8746
460 DEW 0.8745
461 IQZ 0.8745
462 9R5 0.8744
463 LRW 0.8743
464 HSA 0.8741
465 RCV 0.8741
466 HBO 0.8741
467 47V 0.8738
468 9XZ 0.8736
469 NIY 0.8736
470 RGK 0.8736
471 Z5P 0.8735
472 DA4 0.8732
473 5RP 0.8730
474 OCZ 0.8730
475 9F8 0.8730
476 15E 0.8729
477 AVX 0.8728
478 7ME 0.8727
479 PH3 0.8726
480 HJ7 0.8725
481 IDZ 0.8724
482 ICB 0.8723
483 TU0 0.8723
484 1ZC 0.8722
485 VGS 0.8720
486 4MU 0.8719
487 FHC 0.8719
488 GOE 0.8718
489 N0Z 0.8718
490 ALE 0.8717
491 7FU 0.8716
492 XEV 0.8714
493 5GV 0.8713
494 92G 0.8712
495 0K7 0.8711
496 BZ2 0.8707
497 XIZ 0.8705
498 2QV 0.8705
499 VNL 0.8703
500 TOH 0.8702
501 BWD 0.8701
502 39Z 0.8700
503 F6P 0.8699
504 DXP 0.8699
505 BQ5 0.8699
506 M3Q 0.8698
507 CIY 0.8698
508 HCA 0.8696
509 J6W 0.8696
510 FUD 0.8694
511 A5E 0.8692
512 ICO 0.8692
513 LNR 0.8692
514 4NP 0.8691
515 2LW 0.8688
516 6HO 0.8688
517 7UC 0.8686
518 TJM 0.8685
519 AJG 0.8685
520 5GU 0.8683
521 P7V 0.8683
522 IWD 0.8683
523 JFS 0.8683
524 GO8 0.8682
525 UKV 0.8682
526 N2I 0.8682
527 28S 0.8681
528 DDC 0.8680
529 KYN 0.8680
530 ESP 0.8675
531 JGY 0.8673
532 MSR 0.8673
533 7MU 0.8672
534 2PV 0.8671
535 TWO 0.8670
536 2GD 0.8669
537 BA5 0.8669
538 CDJ 0.8665
539 5VJ 0.8665
540 H2W 0.8664
541 STT 0.8664
542 KJU 0.8658
543 DFL 0.8657
544 W8L 0.8657
545 OAI 0.8655
546 14W 0.8655
547 SNU 0.8655
548 272 0.8654
549 TZF 0.8654
550 HC4 0.8651
551 H7S 0.8651
552 96R 0.8649
553 96Z 0.8649
554 2PK 0.8649
555 PPY 0.8644
556 NGA 0.8644
557 M02 0.8643
558 28B 0.8642
559 LIG 0.8641
560 NFM 0.8641
561 4MB 0.8641
562 PH2 0.8640
563 BOQ 0.8640
564 S0D 0.8639
565 AZY 0.8637
566 BIO 0.8636
567 O2Y 0.8635
568 AKG 0.8633
569 3F4 0.8631
570 SG2 0.8631
571 CPZ 0.8630
572 KDV 0.8629
573 MUK 0.8628
574 ZYR 0.8627
575 5WT 0.8626
576 XM5 0.8626
577 MS9 0.8625
578 DNA 0.8621
579 QX4 0.8618
580 28N 0.8614
581 5JT 0.8613
582 5LA 0.8613
583 M83 0.8611
584 CUQ 0.8610
585 ET0 0.8606
586 LF5 0.8606
587 44V 0.8603
588 A98 0.8601
589 TQU 0.8601
590 2D3 0.8600
591 HKK 0.8599
592 H35 0.8597
593 AOR 0.8595
594 2AL 0.8594
595 LWS 0.8594
596 Z21 0.8594
597 0XT 0.8592
598 BNL 0.8591
599 OGA 0.8590
600 3VS 0.8588
601 SZ5 0.8588
602 S62 0.8588
603 K25 0.8588
604 68B 0.8584
605 SNO 0.8580
606 6ZW 0.8579
607 CUT 0.8578
608 GVY 0.8576
609 4NS 0.8575
610 N2Z 0.8575
611 ES2 0.8574
612 4FE 0.8574
613 J1K 0.8571
614 HNT 0.8566
615 78P 0.8564
616 VUP 0.8563
617 6PB 0.8559
618 SU9 0.8557
619 NLG 0.8554
620 URC 0.8551
621 36Y 0.8550
622 DX2 0.8549
623 NNR 0.8548
624 JGB 0.8542
625 E3X 0.8542
626 ZYV 0.8541
627 57D 0.8541
628 M3W 0.8540
629 2KA 0.8532
630 F1X 0.8517
631 25O 0.8510
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3L5R; Ligand: 47X; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3l5r.bio1) has 79 residues
No: Leader PDB Ligand Sequence Similarity
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