Receptor
PDB id Resolution Class Description Source Keywords
6BR8 2.3 Å NON-ENZYME: OTHER STRUCTURE OF A6 REVEALS A NOVEL LIPID TRANSPORTER FOWLPOX VIRUS (STRAIN NVSL) POXVIRUS A6 LIPID BINDING MEMBRANE BIOGENESIS VIRAL PROT
Ref.: STRUCTURE OF A LIPID-BOUND VIRAL MEMBRANE ASSEMBLY REVEALS A MODALITY FOR ENCLOSING THE LIPID BILAYER. PROC. NATL. ACAD. SCI. V. 115 7028 2018 U.S.A.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
6OU B:405;
B:402;
A:405;
A:403;
A:402;
A:401;
B:401;
B:403;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
717.996 C39 H76 N O8 P CCCCC...
PGV B:404;
A:404;
Valid;
Valid;
none;
none;
submit data
749.007 C40 H77 O10 P CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6BR8 2.3 Å NON-ENZYME: OTHER STRUCTURE OF A6 REVEALS A NOVEL LIPID TRANSPORTER FOWLPOX VIRUS (STRAIN NVSL) POXVIRUS A6 LIPID BINDING MEMBRANE BIOGENESIS VIRAL PROT
Ref.: STRUCTURE OF A LIPID-BOUND VIRAL MEMBRANE ASSEMBLY REVEALS A MODALITY FOR ENCLOSING THE LIPID BILAYER. PROC. NATL. ACAD. SCI. V. 115 7028 2018 U.S.A.
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 6BR8 - PGV C40 H77 O10 P CCCCCCCCCC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 6BR8 - PGV C40 H77 O10 P CCCCCCCCCC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 6BR8 - PGV C40 H77 O10 P CCCCCCCCCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 6OU; Similar ligands found: 91
No: Ligand ECFP6 Tc MDL keys Tc
1 LOP 1 1
2 6OU 1 1
3 L9Q 1 1
4 ZPE 0.942857 1
5 GP7 0.868421 1
6 PEH 0.865672 0.980769
7 PEF 0.865672 0.980769
8 PEV 0.865672 0.980769
9 8PE 0.865672 0.980769
10 PTY 0.865672 0.980769
11 9PE 0.852941 0.980769
12 PCW 0.826667 0.79661
13 PEK 0.818182 1
14 PGW 0.776316 0.830189
15 D3D 0.776316 0.830189
16 P50 0.769231 0.924528
17 DR9 0.766234 0.830189
18 PGV 0.766234 0.830189
19 P6L 0.75641 0.830189
20 EPH 0.752941 1
21 D21 0.75 0.792453
22 OZ2 0.746835 0.830189
23 PSC 0.73494 0.79661
24 HGP 0.706667 0.779661
25 6PL 0.706667 0.779661
26 HGX 0.706667 0.779661
27 LIO 0.706667 0.779661
28 PC7 0.706667 0.779661
29 PLD 0.706667 0.779661
30 PEE 0.702703 0.962264
31 B7N 0.695122 0.711864
32 CD4 0.675676 0.807692
33 P5S 0.662338 0.888889
34 PGT 0.657895 0.811321
35 LHG 0.657895 0.811321
36 XP5 0.657895 0.779661
37 PIE 0.647059 0.666667
38 L9R 0.642857 0.728814
39 POV 0.642857 0.728814
40 P3A 0.627907 0.796296
41 3PH 0.625 0.773585
42 F57 0.625 0.773585
43 6PH 0.625 0.773585
44 7PH 0.625 0.773585
45 LPP 0.625 0.773585
46 PX2 0.616438 0.754717
47 7P9 0.616438 0.773585
48 PX8 0.616438 0.754717
49 PCK 0.616279 0.741935
50 CN3 0.609756 0.807692
51 T7X 0.586957 0.711864
52 PII 0.585366 0.694915
53 CN6 0.585366 0.807692
54 42H 0.583333 0.830508
55 PD7 0.575342 0.773585
56 PGK 0.574713 0.767857
57 PSF 0.56962 0.888889
58 3PE 0.567901 0.867925
59 44G 0.564103 0.811321
60 PIZ 0.563218 0.694915
61 CDL 0.5625 0.735849
62 8ND 0.56 0.716981
63 M7U 0.555556 0.773585
64 DGG 0.555556 0.767857
65 DLP 0.554348 0.728814
66 PIF 0.552941 0.683333
67 S12 0.552941 0.888889
68 IP9 0.551724 0.694915
69 NKP 0.551282 0.792453
70 MC3 0.535714 0.711864
71 PC1 0.535714 0.711864
72 PCF 0.535714 0.711864
73 52N 0.534091 0.683333
74 PIO 0.534091 0.683333
75 44E 0.527027 0.773585
76 PDK 0.525253 0.819672
77 AGA 0.505882 0.777778
78 OLC 0.5 0.603774
79 OLB 0.5 0.603774
80 MVC 0.480519 0.603774
81 LPC 0.47619 0.813559
82 LAP 0.47619 0.813559
83 LP3 0.47619 0.813559
84 78N 0.467532 0.603774
85 78M 0.467532 0.603774
86 OPC 0.458333 0.783333
87 NKN 0.435897 0.773585
88 NKO 0.435897 0.773585
89 3XU 0.428571 0.738462
90 CN5 0.420455 0.826923
91 SPU 0.4 0.758065
Ligand no: 2; Ligand: PGV; Similar ligands found: 105
No: Ligand ECFP6 Tc MDL keys Tc
1 DR9 1 1
2 PGV 1 1
3 D3D 0.985507 1
4 PGW 0.985507 1
5 OZ2 0.971831 1
6 P6L 0.957747 1
7 PGT 0.855072 0.977778
8 LHG 0.855072 0.977778
9 L9Q 0.766234 0.830189
10 LOP 0.766234 0.830189
11 6OU 0.766234 0.830189
12 CD4 0.75 0.933333
13 P50 0.75 0.826923
14 ZPE 0.746835 0.830189
15 44G 0.746479 0.977778
16 PCW 0.7375 0.706897
17 PGK 0.7375 0.916667
18 P3A 0.731707 0.956522
19 D21 0.72973 0.913043
20 DGG 0.710843 0.916667
21 B7N 0.678571 0.843137
22 CN3 0.675 0.933333
23 GP7 0.674419 0.830189
24 PSC 0.659091 0.706897
25 CN6 0.65 0.933333
26 8PE 0.649351 0.811321
27 PEF 0.649351 0.811321
28 PEH 0.649351 0.811321
29 PTY 0.649351 0.811321
30 PEV 0.649351 0.811321
31 P5S 0.64557 0.826923
32 9PE 0.641026 0.811321
33 PEE 0.641026 0.796296
34 PEK 0.632184 0.830189
35 PLD 0.625 0.689655
36 HGP 0.625 0.689655
37 PC7 0.625 0.689655
38 HGX 0.625 0.689655
39 6PL 0.625 0.689655
40 LIO 0.625 0.689655
41 PIE 0.613636 0.788462
42 7PH 0.608108 0.891304
43 F57 0.608108 0.891304
44 6PH 0.608108 0.891304
45 3PH 0.608108 0.891304
46 LPP 0.608108 0.891304
47 PX8 0.6 0.869565
48 7P9 0.6 0.891304
49 PX2 0.6 0.869565
50 S12 0.595238 0.826923
51 L9R 0.590909 0.666667
52 POV 0.590909 0.666667
53 EPH 0.589474 0.830189
54 OLB 0.589041 0.733333
55 MVC 0.589041 0.733333
56 OLC 0.589041 0.733333
57 AGA 0.585366 0.934783
58 XP5 0.580247 0.689655
59 PII 0.571429 0.823529
60 42H 0.569767 0.741379
61 CDL 0.567901 0.847826
62 PD7 0.56 0.891304
63 3TF 0.55914 0.618182
64 T7X 0.557895 0.843137
65 NKP 0.556962 0.913043
66 PSF 0.555556 0.826923
67 78N 0.554054 0.733333
68 78M 0.554054 0.733333
69 PIZ 0.550562 0.788462
70 PCK 0.549451 0.655738
71 1O2 0.548387 0.618182
72 TGL 0.542857 0.644444
73 M7U 0.542169 0.891304
74 PIF 0.54023 0.807692
75 IP9 0.539326 0.788462
76 PIO 0.522222 0.807692
77 52N 0.522222 0.807692
78 3PE 0.517647 0.735849
79 L2C 0.513514 0.688889
80 DDR 0.513514 0.688889
81 DGA 0.513514 0.688889
82 FAW 0.513514 0.688889
83 44E 0.513158 0.891304
84 DLP 0.510417 0.666667
85 1L2 0.504951 0.618182
86 MC3 0.488636 0.649123
87 PC1 0.488636 0.649123
88 PCF 0.488636 0.649123
89 PDK 0.485437 0.704918
90 GGD 0.481132 0.625
91 LBR 0.469136 0.638298
92 GYM 0.465753 0.711111
93 1QW 0.465753 0.711111
94 LAP 0.465116 0.724138
95 LP3 0.465116 0.724138
96 LPC 0.465116 0.724138
97 PGM 0.457831 0.913043
98 NKO 0.443038 0.891304
99 NKN 0.443038 0.891304
100 SQD 0.43299 0.630769
101 G2A 0.430556 0.652174
102 2JT 0.430556 0.652174
103 CN5 0.426966 0.913043
104 DGD 0.421569 0.607143
105 OPC 0.405941 0.694915
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6BR8; Ligand: PGV; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6br8.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6br8.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 6br8.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 6br8.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 6br8.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 6br8.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 6br8.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 6br8.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 6BR8; Ligand: PGV; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 6br8.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 6BR8; Ligand: 6OU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 6br8.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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