Receptor
PDB id Resolution Class Description Source Keywords
6BHQ 2.05 Å NON-ENZYME: OTHER MOUSE IMMUNOGLOBULIN G 2C FC FRAGMENT WITH COMPLEX-TYPE GLYC MUS MUSCULUS IMMUNE SYSTEM
Ref.: MOUSE IGG2C FC LOOP RESIDUES PROMOTE GREATER RECEPTOR-BINDING AFFINITY THAN MOUSE IGG2B OR HUMAN PLOS ONE V. 13 92123 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:509;
 Invalid;
 none;
 submit data
92.094 C3 H8 O3 C(C(C...
NAG NAG FUL BMA MAN MAN NAG GAL C:1;
D:1;
 Invalid;
Valid;
 none;
none;
 submit data
1406.3 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6BHQ 2.05 Å NON-ENZYME: OTHER MOUSE IMMUNOGLOBULIN G 2C FC FRAGMENT WITH COMPLEX-TYPE GLYC MUS MUSCULUS IMMUNE SYSTEM
Ref.: MOUSE IGG2C FC LOOP RESIDUES PROMOTE GREATER RECEPTOR-BINDING AFFINITY THAN MOUSE IGG2B OR HUMAN PLOS ONE V. 13 92123 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 6BHQ - NAG NAG FUL BMA MAN MAN NAG GAL n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 1H3T - BMA C6 H12 O6 C([C@@H]1[....
2 6BHQ - NAG NAG FUL BMA MAN MAN NAG GAL n/a n/a
3 4L4J - NAG NAG BMA MAN NAG n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 1H3T - BMA C6 H12 O6 C([C@@H]1[....
2 6BHQ - NAG NAG FUL BMA MAN MAN NAG GAL n/a n/a
3 4L4J - NAG NAG BMA MAN NAG n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: NAG NAG FUL BMA MAN MAN NAG GAL; Similar ligands found: 71
No: Ligand ECFP6 Tc MDL keys Tc
1 NAG NAG FUL BMA MAN MAN NAG GAL 1 1
2 NAG NAG BMA MAN MAN MAN MAN 0.752212 0.981132
3 NAG NAG BMA MAN MAN NAG NAG 0.719298 1
4 C4W NAG FUC BMA MAN MAN NAG 0.719008 0.875
5 C4W NAG FUC BMA MAN MAN NAG GAL NAG 0.688 0.790323
6 NAG BMA MAN MAN NAG GAL NAG GAL 0.663717 0.924528
7 C4W NAG FUC BMA MAN MAN NAG NAG 0.66129 0.875
8 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.661017 0.90566
9 C4W NAG FUC BMA MAN NAG GAL 0.644628 0.790323
10 NAG NAG BMA MAN MAN NAG GAL NAG 0.644068 0.924528
11 NAG NAG BMA MAN 0.638889 0.981132
12 NDG BMA MAN MAN NAG GAL NAG 0.635593 0.924528
13 NAG NAG MAN MAN MAN 0.625 0.90566
14 C4W NAG FUC BMA MAN 0.618644 0.875
15 C4W NAG FUC BMA MAN NAG 0.617886 0.875
16 BMA MAN MAN NAG GAL NAG 0.598291 0.90566
17 NAG NAG BMA 0.584906 0.981132
18 NDG BMA MAN MAN NAG MAN MAN 0.577236 0.90566
19 NAG BMA MAN MAN MAN MAN MAN MAN MAN MAN 0.576271 0.849057
20 BGC GAL NAG NAG GAL GAL 0.568965 0.90566
21 C4W NAG FUC BMA 0.568965 0.875
22 BGC FUC GAL NAG GAL 0.542373 0.867925
23 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.541667 0.849057
24 C4W NAG FUC BMA MAN MAN NAG GAL SIA NAG 0.53125 0.809524
25 NAG ASN NAG BMA MAN MAN NAG NAG 0.522388 0.894737
26 ALA ASN LYS NAG NAG BMA MAN MAN NAG NAG 0.522388 0.910714
27 NAG NAG BMA BMA 0.517544 0.981481
28 GAL NAG GAL NAG GAL 0.508929 0.90566
29 NAG BMA MAN MAN MAN MAN 0.504202 0.849057
30 C4W NAG FUC BMA MAN NAG GAL SIA 0.496774 0.809524
31 NAG GAL NAG GAL 0.495575 0.90566
32 NAG GAL NAG GAL NAG GAL 0.495575 0.924528
33 NAG NAG NAG NAG NAG NAG NAG 0.495495 1
34 NAG NAG NAG NAG 0.495495 1
35 NAG NAG NAG 0.495495 1
36 NAG NAG BMA MAN NAG 0.491667 0.924528
37 MAN MAN MAN NAG NAG 0.487179 0.90566
38 YZ0 MAN MAN NAG MAN 0.483607 0.851852
39 MAN NAG GAL 0.481818 0.849057
40 GAL NAG GAL 0.477477 0.849057
41 NDG GLA GLC NAG GLC RAM 0.477273 0.924528
42 NDG GLA NAG GLC RAM 0.476923 0.924528
43 NDG NAG GLA NAG GLC RAM 0.476923 0.924528
44 NAG BMA 0.462264 0.90566
45 BGC GAL NAG GAL FUC 0.459677 0.867925
46 BGC GAL NAG GAL FUC FUC 0.456693 0.886792
47 1GN ACY GAL 1GN BGC ACY GAL BGC 0.455285 0.90566
48 BMA MAN MAN MAN 0.442478 0.648148
49 MAN MAN MAN MAN MAN MAN MAN 0.440678 0.622642
50 NAG GAL GAL 0.4375 0.849057
51 MAN BMA MAN MAN MAN MAN MAN 0.434426 0.62963
52 YZ0 MAN Z4Y NAG MAN 0.433824 0.807018
53 BGC FUC GAL NAG 0.430894 0.867925
54 BMA Z4Y NAG 0.429752 0.833333
55 NAG GAL BGC GAL 0.42735 0.849057
56 GLC GAL NAG GAL FUC GLA 0.419847 0.867925
57 NAG BMA MAN MAN MAN MAN MAN 0.416667 0.625
58 BMA NGT MAN MAN 0.416 0.634921
59 GLC GAL NAG GAL FUC A2G 0.414815 0.924528
60 NAG GAL FUC A2G 0.413793 0.867925
61 BGC GAL GLA NGA 0.413223 0.849057
62 BGC GAL NAG GAL 0.411765 0.849057
63 GAL NAG FUC GAL 0.409836 0.867925
64 BGC GAL GLA NGA GAL 0.409836 0.849057
65 GAL NAG GAL FUC FUC 0.408 0.886792
66 MMA MAN NAG MAN NAG NAG 0.408 0.907407
67 NAG GAL NAG 0.40678 0.90566
68 BGC GAL NAG 0.40678 0.849057
69 BGC GAL NAG GAL SIA 0.402685 0.927273
70 BGC BGC BGC BGC 0.4 0.622642
71 GAL NAG GAL FUC 0.4 0.90566
Similar Ligands (3D)
Ligand no: 1; Ligand: NAG NAG FUL BMA MAN MAN NAG GAL; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6BHQ; Ligand: NAG NAG FUL BMA MAN MAN NAG GAL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6bhq.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 6BHQ; Ligand: NAG NAG FUL BMA MAN MAN NAG GAL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6bhq.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
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