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Receptor
PDB id Resolution Class Description Source Keywords
6BHQ 2.05 Å NON-ENZYME: OTHER MOUSE IMMUNOGLOBULIN G 2C FC FRAGMENT WITH COMPLEX-TYPE GLYC MUS MUSCULUS IMMUNE SYSTEM
Ref.: MOUSE IGG2C FC LOOP RESIDUES PROMOTE GREATER RECEPTOR-BINDING AFFINITY THAN MOUSE IGG2B OR HUMAN PLOS ONE V. 13 92123 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:509;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
NAG NAG FUL BMA MAN MAN NAG GAL A:501;
B:501;
Invalid;
Valid;
none;
none;
submit data
1406.3 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6BHQ 2.05 Å NON-ENZYME: OTHER MOUSE IMMUNOGLOBULIN G 2C FC FRAGMENT WITH COMPLEX-TYPE GLYC MUS MUSCULUS IMMUNE SYSTEM
Ref.: MOUSE IGG2C FC LOOP RESIDUES PROMOTE GREATER RECEPTOR-BINDING AFFINITY THAN MOUSE IGG2B OR HUMAN PLOS ONE V. 13 92123 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 6BHQ - NAG NAG FUL BMA MAN MAN NAG GAL n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 1H3T - BMA C6 H12 O6 C([C@@H]1[....
2 6BHQ - NAG NAG FUL BMA MAN MAN NAG GAL n/a n/a
3 4L4J - NAG NAG BMA MAN NAG n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 1H3T - BMA C6 H12 O6 C([C@@H]1[....
2 6BHQ - NAG NAG FUL BMA MAN MAN NAG GAL n/a n/a
3 4L4J - NAG NAG BMA MAN NAG n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAG NAG FUL BMA MAN MAN NAG GAL; Similar ligands found: 86
No: Ligand ECFP6 Tc MDL keys Tc
1 NAG NAG FUL BMA MAN MAN NAG GAL 1 1
2 NAG NAG BMA MAN MAN MAN MAN 0.752212 0.981132
3 NAG NAG BMA MAN MAN NAG NAG 0.719298 1
4 FUC C4W NAG BMA MAN MAN NAG 0.719008 0.875
5 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.681416 0.924528
6 NAG NAG BMA MAN NAG 0.672566 1
7 NAG MAN MAN MAN NAG GAL NAG GAL 0.663717 0.924528
8 MAN BMA NAG NAG MAN NAG GAL GAL 0.663717 0.924528
9 FUC C4W NAG BMA MAN MAN NAG NAG 0.66129 0.875
10 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.661017 0.90566
11 NAG NAG BMA MAN MAN NAG GAL NAG 0.644068 0.924528
12 NAG NAG BMA MAN 0.638889 0.981132
13 NAG MAN BMA NDG MAN NAG GAL 0.635593 0.924528
14 NAG NAG BMA MAN MAN 0.625 0.90566
15 FUC C4W NAG BMA MAN 0.618644 0.875
16 FUC C4W NAG BMA MAN NAG 0.617886 0.875
17 NAG BMA NAG MAN MAN NAG NAG 0.601695 0.924528
18 NAG MAN BMA MAN NAG GAL 0.598291 0.90566
19 NAG NAG BMA 0.584906 0.981132
20 NAG NDG BMA 0.584906 0.981132
21 M5G 0.577236 0.90566
22 FUC C4W NAG BMA 0.568965 0.875
23 FUC BGC GAL NAG GAL 0.542373 0.867925
24 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.541667 0.849057
25 GAL NAG GAL BGC 0.530973 0.886792
26 ASN NAG NAG BMA MAN MAN NAG NAG 0.522388 0.894737
27 NAG NAG BMA BMA 0.517544 0.981481
28 NAG GAL GAL NAG GAL 0.508929 0.90566
29 GLC GAL NAG GAL 0.504425 0.849057
30 LAT NAG GAL 0.504425 0.849057
31 NAG BMA MAN MAN MAN MAN 0.504202 0.849057
32 NAG GAL GAL NAG 0.495575 0.90566
33 GAL NAG GAL NAG GAL NAG 0.495575 0.924528
34 NAG NAG NAG 0.495495 1
35 NAG NAG NAG NAG 0.495495 1
36 NAG MAN MAN MAN NAG 0.487179 0.90566
37 WZ5 0.483607 0.851852
38 GAL NAG MAN 0.481818 0.849057
39 NAG MAN MAN 0.477876 0.849057
40 GAL NAG GAL 0.477876 0.886792
41 MAN MAN MAN BMA MAN 0.473214 0.622642
42 NAG BMA 0.462264 0.90566
43 FUC GAL NAG GAL BGC 0.459677 0.867925
44 GLC NAG GAL GAL FUC 0.459677 0.867925
45 GAL GLC NAG GAL FUC 0.459677 0.867925
46 GLC GAL NAG GAL FUC FUC 0.456693 0.886792
47 BGC GAL NAG GAL FUC FUC 0.456693 0.886792
48 ACY 1GN GAL 1GN BGC ACY GAL BGC 0.455285 0.90566
49 1GN ACY GAL ACY 1GN BGC GAL BGC 0.455285 0.90566
50 MAN MAN MAN MAN MAN MAN MAN 0.440678 0.622642
51 GLA GAL NAG 0.4375 0.849057
52 MAN BMA NAG 0.4375 0.849057
53 MAN MAN MAN BMA MAN MAN MAN 0.434426 0.62963
54 WZ4 0.433824 0.807018
55 BMA MAN MAN MAN MAN 0.433628 0.622642
56 NAG NDG 0.432432 0.962264
57 NAG NAG 0.432432 0.962264
58 FUC BGC GAL NAG 0.430894 0.867925
59 BMA Z4Y NAG 0.429752 0.833333
60 GAL BGC NAG GAL 0.42735 0.849057
61 FUC NAG GAL 0.422414 0.943396
62 GLA GAL NAG FUC GAL GLC 0.419847 0.867925
63 NAG BMA MAN MAN MAN MAN MAN 0.416667 0.625
64 BMA NGT MAN MAN 0.416 0.634921
65 A2G GAL NAG FUC GAL GLC 0.414815 0.924528
66 GLC GAL NAG GAL FUC A2G 0.414815 0.924528
67 FUC GAL NAG 0.413793 0.867925
68 FUL GAL NAG 0.413793 0.867925
69 DR2 0.413793 0.867925
70 NDG GAL FUC 0.413793 0.867925
71 FUC GAL NDG 0.413793 0.867925
72 NAG GAL FUC 0.413793 0.867925
73 GAL NAG FUC 0.413793 0.867925
74 NGA GLA GAL BGC 0.413223 0.849057
75 GAL NAG GAL GLC 0.411765 0.849057
76 BGC GAL NAG GAL 0.411765 0.849057
77 GAL NGA GLA BGC GAL 0.409836 0.849057
78 GAL NAG GAL FUC 0.409836 0.867925
79 GLA NAG GAL FUC 0.409836 0.867925
80 MMA MAN NAG MAN NAG NAG 0.408 0.907407
81 FUC GAL NAG GAL FUC 0.408 0.886792
82 NAG GAL NAG 0.40678 0.90566
83 NAG GAL BGC 0.40678 0.849057
84 BGC GAL NAG SIA GAL 0.402685 0.927273
85 SIA GAL NAG GAL GLC 0.402685 0.927273
86 SIA GAL NAG GAL BGC 0.402685 0.927273
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6BHQ; Ligand: NAG NAG FUL BMA MAN MAN NAG GAL; Similar sites found with APoc: 45
This union binding pocket(no: 1) in the query (biounit: 6bhq.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 4IPH 1FJ None
2 1AUA BOG 1.33929
3 6GNO XDI 1.48148
4 2FB3 GTP 1.78571
5 1MJT ITU 2.23214
6 5ETR 5RW 2.48447
7 5ETR APC 2.48447
8 5XEG AKG 2.67857
9 6MPT C30 3.14685
10 1VA6 P2S 3.57143
11 1VA6 ADP 3.57143
12 4CS4 AXZ 3.57143
13 5IVE 6E8 3.57143
14 3GDN MXN 3.57143
15 4NV7 COA 3.57143
16 2BW7 APC 3.65297
17 2BW7 ECS 3.65297
18 2X3F APC 4.01786
19 5UWA 8ND 4.4335
20 5LX9 OLB 4.46429
21 3SLS 77D 4.46429
22 2XG5 EC2 4.62428
23 2XG5 EC5 4.62428
24 3COW 52H 4.91071
25 4OPC FDA 5.80357
26 4OPC PGT 5.80357
27 4PU5 ANP 6.25
28 3E2M E2M 6.48649
29 5XDT MB3 6.69643
30 5XDT GDP 6.69643
31 6GR0 F8W 6.89655
32 5LRT ADP 7.14286
33 5N9T 8QQ 7.58929
34 2AG4 LP3 8.53659
35 2AG4 OLA 8.53659
36 1YQC GLV 8.82353
37 3TCT 3MI 9.44882
38 1KGI T4A 9.44882
39 4FHD 0TT 9.82143
40 4FHD EEM 9.82143
41 4U9U FAD 10.2679
42 4D06 NAR 11.6071
43 5W4W 9WG 12.0536
44 3VQ2 LP4 LP5 MYR DAO 15.2778
45 1YRO UDP 15.4472
Pocket No.: 2; Query (leader) PDB : 6BHQ; Ligand: NAG NAG FUL BMA MAN MAN NAG GAL; Similar sites found with APoc: 39
This union binding pocket(no: 2) in the query (biounit: 6bhq.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL None
2 2BOS GLA GAL GLC None
3 3WV6 GAL BGC 1.78571
4 1ELI PYC 1.78571
5 2D6M LBT 1.88679
6 2E56 MYR 2.08333
7 5DG2 GAL GLC 2.22222
8 5BVE 4VG 2.23214
9 4BG4 ADP 2.23214
10 1VRP ADP 2.67857
11 1M15 ADP 2.67857
12 1M15 ARG 2.67857
13 3BGD PM6 3.125
14 4WOE ADP 3.125
15 6FP4 FAD 3.125
16 3NC9 TR3 3.57143
17 3LVW GSH 3.57143
18 4CS4 ANP 3.57143
19 1IS3 LAT 3.7037
20 3JU6 ANP 4.01786
21 1G0N PHH 4.01786
22 1G0N NDP 4.01786
23 3NV3 GAL NAG MAN 5.07246
24 2GJ5 VD3 6.17284
25 5GLT BGC GAL NAG GAL 6.25
26 5TPV TYD 6.53595
27 2W5P CL8 6.71141
28 4YZC STU 7.58929
29 6FOF LAT 7.65306
30 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU 7.89474
31 3AD8 FAD 8.03571
32 3AD8 PYC 8.03571
33 5NFB 8VT 8.52273
34 3I8T LBT 9.14634
35 1UNB AKG 9.82143
36 1UNB PN1 9.82143
37 4RF7 ARG 10.2679
38 2IUW AKG 10.5042
39 5KJW 53C 12.0536
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