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Receptor
PDB id Resolution Class Description Source Keywords
5igj 1.4 Å EC: 2.-.-.- MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GUANOS CLARITHROMYCIN ESCHERICHIA COLI MACROLIDE PHOSPHOTRANSFERASE KINASE TRANSFERASE-ANTIBIOTIC
Ref.: STRUCTURAL BASIS FOR KINASE-MEDIATED MACROLIDE ANTI RESISTANCE. STRUCTURE V. 25 750 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
IPA A:403;
Invalid;
none;
submit data
60.095 C3 H8 O CC(C)...
GMP A:401;
Valid;
none;
submit data
283.241 C10 H13 N5 O5 c1nc2...
CTY A:402;
Valid;
none;
Kd = 0.18 uM
747.953 C38 H69 N O13 CC[C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5IGI 1.2 Å EC: 2.-.-.- MACROLIDE 2'-PHOSPHOTRANSFERASE TYPE I - COMPLEX WITH GUANOS AZITHROMYCIN ESCHERICHIA COLI MACROLIDE PHOSPHOTRANSFERASE KINASE TRANSFERASE-ANTIBIOTIC
Ref.: STRUCTURAL BASIS FOR KINASE-MEDIATED MACROLIDE ANTI RESISTANCE. STRUCTURE V. 25 750 2017
Members (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5IGT Kd = 0.2 uM ERY C37 H67 N O13 CC[C@@H]1[....
2 5IGI Kd = 0.17 uM ZIT C38 H72 N2 O12 CC[C@@H]1[....
3 5IGP Kd = 0.2 uM ERY C37 H67 N O13 CC[C@@H]1[....
4 5IGR - ZIO C35 H61 N O12 C[C@@H]1C[....
5 5IGS - GMP C10 H13 N5 O5 c1nc2c(n1[....
6 5IGJ Kd = 0.18 uM CTY C38 H69 N O13 CC[C@@H]1[....
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 5IGT Kd = 0.2 uM ERY C37 H67 N O13 CC[C@@H]1[....
2 5IGI Kd = 0.17 uM ZIT C38 H72 N2 O12 CC[C@@H]1[....
3 5IGP Kd = 0.2 uM ERY C37 H67 N O13 CC[C@@H]1[....
4 5IGR - ZIO C35 H61 N O12 C[C@@H]1C[....
5 5IGS - GMP C10 H13 N5 O5 c1nc2c(n1[....
6 5IGJ Kd = 0.18 uM CTY C38 H69 N O13 CC[C@@H]1[....
50% Homology Family (13)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 5IGY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5IGV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 5IH1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 5IGZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 5IGW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 5IH0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 5IWU - ERY C37 H67 N O13 CC[C@@H]1[....
8 5IGT Kd = 0.2 uM ERY C37 H67 N O13 CC[C@@H]1[....
9 5IGI Kd = 0.17 uM ZIT C38 H72 N2 O12 CC[C@@H]1[....
10 5IGP Kd = 0.2 uM ERY C37 H67 N O13 CC[C@@H]1[....
11 5IGR - ZIO C35 H61 N O12 C[C@@H]1C[....
12 5IGS - GMP C10 H13 N5 O5 c1nc2c(n1[....
13 5IGJ Kd = 0.18 uM CTY C38 H69 N O13 CC[C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GMP; Similar ligands found: 112
No: Ligand ECFP6 Tc MDL keys Tc
1 GMP 1 1
2 G 0.732394 0.866667
3 5GP 0.732394 0.866667
4 3GP 0.704225 0.853333
5 GDP 0.684211 0.88
6 GNH 0.675325 0.868421
7 GP3 0.671053 0.857143
8 GP2 0.662338 0.846154
9 GTP 0.658228 0.88
10 2GP 0.657534 0.866667
11 GSP 0.641975 0.835443
12 G2P 0.641975 0.846154
13 ALF 5GP 0.6375 0.802469
14 GMV 0.6375 0.857143
15 GPG 0.635294 0.87013
16 G1R 0.62963 0.868421
17 GCP 0.62963 0.857143
18 GAV 0.626506 0.846154
19 GKE 0.625 0.87013
20 GDC 0.625 0.87013
21 GDD 0.625 0.87013
22 GNP 0.621951 0.857143
23 9GM 0.621951 0.857143
24 ALF GDP 0.593023 0.802469
25 GDP AF3 0.593023 0.802469
26 GDP ALF 0.593023 0.802469
27 G4P 0.588235 0.866667
28 G2R 0.586207 0.846154
29 G3D 0.583333 0.866667
30 P2G 0.576923 0.815789
31 SGP 0.576923 0.78481
32 G G 0.565217 0.833333
33 GFB 0.565217 0.846154
34 GDR 0.565217 0.846154
35 GKD 0.56383 0.87013
36 P1G 0.5625 0.805195
37 0O2 0.561798 0.866667
38 YGP 0.56044 0.792683
39 G3A 0.55914 0.857143
40 6CK 0.55914 0.825
41 Y9Z 0.554348 0.817073
42 G5P 0.553191 0.857143
43 NOS 0.549296 0.940298
44 GTG 0.548387 0.825
45 JB2 0.547368 0.846154
46 GDX 0.541667 0.857143
47 GPD 0.541667 0.814815
48 U2G 0.54 0.848101
49 GCP G 0.538462 0.828947
50 GDP 7MG 0.536842 0.822785
51 35G 0.53012 0.84
52 C2E 0.53012 0.828947
53 PCG 0.53012 0.84
54 CG2 0.529412 0.848101
55 5GP 5GP 0.52381 0.815789
56 MG7 0.520548 0.957143
57 JB3 0.514852 0.835443
58 A G 0.504762 0.844156
59 G A A A 0.504762 0.857143
60 U A G G 0.5 0.844156
61 AKW 0.495146 0.783133
62 FEG 0.495146 0.77381
63 NGD 0.495146 0.846154
64 ZGP 0.490385 0.764706
65 G U 0.490385 0.835443
66 G U34 0.490385 0.825
67 GH3 0.488889 0.855263
68 DG 0.487805 0.797468
69 DGP 0.487805 0.797468
70 2MD 0.481132 0.785714
71 G C 0.481132 0.835443
72 BGO 0.480769 0.8125
73 GPX 0.478261 0.828947
74 XTS 0.472973 0.913043
75 DGI 0.471264 0.810127
76 MGD 0.46789 0.785714
77 CAG 0.46789 0.776471
78 TPG 0.45614 0.741573
79 FE9 0.455357 0.684211
80 4BW 0.454545 0.828947
81 1YD 0.454545 0.828947
82 G G G RPC 0.453704 0.7875
83 GGM 0.453704 0.792683
84 SNI 0.453333 0.898551
85 PGD 0.451327 0.814815
86 MD1 0.451327 0.785714
87 DGT 0.450549 0.810127
88 APC G U 0.45045 0.797468
89 DBG 0.443478 0.835443
90 G1R G1R 0.443478 0.835443
91 13A 0.441558 0.768293
92 GPC 0.441441 0.795181
93 PGD O 0.439655 0.75
94 DG DG 0.43299 0.802469
95 G4M 0.430894 0.797619
96 G G G C 0.429825 0.802469
97 A G C C 0.426087 0.822785
98 1YC 0.421569 0.802632
99 AD3 0.421053 0.882353
100 4UR 0.416667 0.828947
101 G C C C 0.411765 0.8125
102 XYA 0.410959 0.882353
103 RAB 0.410959 0.882353
104 ADN 0.410959 0.882353
105 G1G 0.408696 0.814815
106 1DA 0.407895 0.882353
107 AC2 0.407895 0.797297
108 IMP 0.406977 0.84
109 A G U 0.404762 0.825
110 3ZE 0.404494 0.772152
111 MZR 0.402778 0.838235
112 CFE 0.4 0.857143
Ligand no: 2; Ligand: CTY; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 CTY 1 1
2 ERY 0.831776 0.981481
3 ZIT 0.663934 0.881356
4 ERB 0.652542 0.962963
5 EY5 0.544715 0.981481
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5IGI; Ligand: ZIT; Similar sites found with APoc: 202
This union binding pocket(no: 1) in the query (biounit: 5igi.bio1) has 38 residues
No: Leader PDB Ligand Sequence Similarity
1 2VWA PTY None
2 5WBF LAC 1.11111
3 5ZCT ANP 1.3289
4 5WNL STU 1.3289
5 3BU5 ATP 1.3289
6 1NXJ TLA 1.63934
7 2PZI AXX 1.66113
8 5X8I SQZ 1.66113
9 5ODT ADP 1.76678
10 5FQK 6NT 1.85874
11 5DZT AMP 1.99336
12 4OCJ NDG 1.99336
13 5VCV 1N1 1.99336
14 5AX9 4KT 1.99336
15 5E4R 40E 1.99336
16 4XDZ 40E 1.99336
17 4YMJ 4EJ 1.99336
18 4IJP 1EH 1.99336
19 4Y85 499 1.99336
20 3DAK ANP 2.06897
21 1U59 STU 2.09059
22 4G86 BNT 2.11268
23 5NM7 GLY 2.25564
24 5I35 ANP 2.32558
25 4AZW ATP 2.32558
26 4UX9 ANP 2.32558
27 4UAL 3FV 2.32558
28 5JDA AMP 2.32558
29 5MW8 ATP 2.32558
30 2GN2 C5P 2.32558
31 3TXO 07U 2.32558
32 4WB6 ATP 2.32558
33 4WB7 ATP 2.32558
34 3PTG 932 2.32558
35 2Q7D ANP 2.32558
36 4IZY 1J2 2.32558
37 1RE8 BD2 2.32558
38 3SLS ANP 2.32558
39 4YZN 4K5 2.43902
40 5A6N U7E 2.4735
41 5LXB 7A9 2.47934
42 2B6N ALA PRO THR 2.51799
43 4BTK DTQ 2.65781
44 2Z7R STU 2.65781
45 5DXT 5H5 2.65781
46 4NFN 2KC 2.65781
47 6GIN IR2 2.65781
48 4AUA 4AU 2.65781
49 3HZT J60 2.65781
50 5Y86 HRM 2.65781
51 5C1P ADP 2.65781
52 5ZTN CUR 2.65781
53 2QCS ANP 2.74914
54 3UIM ANP 2.99003
55 5VZ0 ADP 2.99003
56 3KN5 ANP 2.99003
57 4XZ3 ACP 2.99003
58 5EQY 5RA 2.99003
59 3RWP ABQ 2.99003
60 3WVR AMP 2.99003
61 3M2W L8I 3.01003
62 2QCX PF1 3.04183
63 4XYM A12 3.04348
64 4E1Z 0MX 3.09278
65 3SRV S19 3.2491
66 3VOT ADP 3.32226
67 6AC9 ANP 3.32226
68 4OCV ANP 3.32226
69 4Y0X ADP 3.32226
70 4XH0 ADP 3.32226
71 4OTH DRN 3.32226
72 4G17 0VN 3.33333
73 2V7O DRN 3.65448
74 4UWH JXM 3.65448
75 5U6C 7YS 3.65448
76 6G34 5ID 3.65448
77 2CSN CKI 3.7037
78 1ION ADP 3.7037
79 4AU8 Z3R 3.71622
80 4NST AF3 3.73134
81 2YAK OSV 3.85965
82 5LX9 OLB 3.87324
83 2IF8 ADP 3.98671
84 3ALN ANP 3.98671
85 2B56 U5P 3.98671
86 2F2U M77 3.98671
87 6GN6 MAL 3.98671
88 1ZDQ MSM 3.98671
89 5CKW ANP 3.99113
90 5Y80 IRE 4.05405
91 2YAB AMP 4.31894
92 2BPM 529 4.31894
93 2BP1 FLC 4.31894
94 5WO4 B7V 4.31894
95 6GUE FB8 4.47761
96 4BCN T9N 4.58015
97 4BCQ TJF 4.58015
98 4CFU 2WC 4.58015
99 6CGZ HL6 4.60993
100 5FI4 5XV 4.64396
101 4R78 AMP 4.65116
102 3CY2 MB9 4.65116
103 3RE4 TO1 4.65116
104 4N70 2HX 4.65116
105 3HYW DCQ 4.65116
106 4WOV 3SM 4.65116
107 5LMK 6ZK 4.65116
108 2ZV2 609 4.69799
109 4OKE AMP 4.7619
110 6BR8 6OU 4.7619
111 5N26 CPT 4.94506
112 3VPD ANP 4.98221
113 3F7Z 34O 4.98339
114 4NM5 ADP 4.98339
115 3ORK AGS 4.98339
116 4IX4 ADP 4.98339
117 2JLD AG1 4.98339
118 2AQX ATP 5.19031
119 2A19 ANP 5.28169
120 1M0W ANP 5.31561
121 5DMZ ADP 5.31561
122 6CMJ F6J 5.31561
123 1XJD STU 5.31561
124 3PN1 IVH 5.31561
125 4BHN BH9 5.31561
126 1Q8Y ADP 5.31561
127 4JR7 GNP 5.64784
128 3GGF GVD 5.64784
129 3W5N RAM 5.64784
130 1UNH IXM 5.76923
131 6EZ6 C5Z 5.98007
132 5OMY 9YE 5.98007
133 5AE9 OKO 5.98007
134 3PE2 E1B 5.98007
135 3LXN MI1 5.98007
136 4XDY HIO 5.98007
137 2PVN P63 5.98007
138 1PHK ATP 6.04027
139 3K5I ADP 6.31229
140 3FHR P4O 6.31229
141 4NW6 2NS 6.31229
142 6BJO DUY 6.4
143 4Q5H ANP 6.41026
144 2VZ6 FEF 6.64452
145 4X7Q 3YR 6.64452
146 6A1G 9OL 6.64452
147 5LPZ ADP 6.64452
148 4OH4 ANP 6.64452
149 5YF9 NIO 6.64452
150 5LPB ADP 6.75676
151 1W2D 4IP 6.79245
152 1W2D ADP 6.79245
153 4WNP 3RJ 6.96864
154 3DLS ADP 6.97674
155 2VN9 GVD 6.97674
156 6BFN DL1 6.97674
157 4LRJ ANP 7.10059
158 6GZD LCI 7.30897
159 2R5T ANP 7.5067
160 2PYW ADP 7.6412
161 2B9J ADP 7.6412
162 2B9F ADP 7.6412
163 2B9I ADP 7.6412
164 3X01 AMP 7.97342
165 3O0G 3O0 8.05369
166 4V3I ASP LEU THR ARG PRO 8.17121
167 3KU0 ADE 8.36653
168 4WW7 AMP 8.42912
169 5W7B MYR 8.51064
170 4FG8 ATP 8.63787
171 4BFM ANP 8.63787
172 5TDF ADP 8.9701
173 5UGW GSH 9.14286
174 1T0S BML 9.63455
175 2JDR L20 9.96678
176 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 9.96678
177 4IDT T28 10.299
178 5OES ADP 10.6312
179 5NNT DPV 10.8108
180 2H8H H8H 11.2957
181 1Y57 MPZ 11.2957
182 3V4S ATP 11.6279
183 3IDB ANP 11.8012
184 4U98 ACP 12.6246
185 3W0O ADP 13.6213
186 3W0O HY0 13.6213
187 2BKK ADP 13.6364
188 3TM0 B31 13.6882
189 3TM0 ANP 13.6882
190 6CGD GNP 15.2824
191 6CGD AKN 15.2824
192 3FHI ANP 16.8831
193 3NOJ PYR 17.2269
194 4H3Q ANP 17.9402
195 3ZRM ZRM 18.75
196 3RV5 DXC 20.2247
197 4DFU QUE 32.2259
198 4DFB KAN 32.2259
199 4DFU KAN 32.2259
200 5C4L SIS 32.5581
201 5C4L 4XR 32.5581
202 3TDV GDP 39.8671
Pocket No.: 2; Query (leader) PDB : 5IGI; Ligand: GMP; Similar sites found with APoc: 204
This union binding pocket(no: 2) in the query (biounit: 5igi.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 2VWA PTY None
2 5WBF LAC 1.11111
3 5ZCT ANP 1.3289
4 5WNL STU 1.3289
5 3BU5 ATP 1.3289
6 4MGD 27N 1.56863
7 1NXJ TLA 1.63934
8 2PZI AXX 1.66113
9 5X8I SQZ 1.66113
10 1OUK 084 1.66113
11 5ODT ADP 1.76678
12 5FQK 6NT 1.85874
13 5DZT AMP 1.99336
14 4OCJ NDG 1.99336
15 5VCV 1N1 1.99336
16 5AX9 4KT 1.99336
17 5E4R 40E 1.99336
18 4XDZ 40E 1.99336
19 4YMJ 4EJ 1.99336
20 3NIP 16D 1.99336
21 4IJP 1EH 1.99336
22 4Y85 499 1.99336
23 3DAK ANP 2.06897
24 1U59 STU 2.09059
25 4G86 BNT 2.11268
26 5NM7 GLY 2.25564
27 5I35 ANP 2.32558
28 4AZW ATP 2.32558
29 4UX9 ANP 2.32558
30 4UAL 3FV 2.32558
31 5JDA AMP 2.32558
32 5MW8 ATP 2.32558
33 2GN2 C5P 2.32558
34 4WB6 ATP 2.32558
35 1RE8 BD2 2.32558
36 4WB7 ATP 2.32558
37 3PTG 932 2.32558
38 2Q7D ANP 2.32558
39 4IZY 1J2 2.32558
40 3SLS ANP 2.32558
41 4YZN 4K5 2.43902
42 5A6N U7E 2.4735
43 5LXB 7A9 2.47934
44 2B6N ALA PRO THR 2.51799
45 4BTK DTQ 2.65781
46 2Z7R STU 2.65781
47 5DXT 5H5 2.65781
48 4NFN 2KC 2.65781
49 6GIN IR2 2.65781
50 4AUA 4AU 2.65781
51 5Y86 HRM 2.65781
52 5C1P ADP 2.65781
53 3HZT J60 2.65781
54 5ZTN CUR 2.65781
55 2QCS ANP 2.74914
56 3UIM ANP 2.99003
57 5VZ0 ADP 2.99003
58 3KN5 ANP 2.99003
59 4XZ3 ACP 2.99003
60 5EQY 5RA 2.99003
61 3RWP ABQ 2.99003
62 3WVR AMP 2.99003
63 3M2W L8I 3.01003
64 2QCX PF1 3.04183
65 4XYM A12 3.04348
66 4E1Z 0MX 3.09278
67 3SRV S19 3.2491
68 3VOT ADP 3.32226
69 6AC9 ANP 3.32226
70 4OCV ANP 3.32226
71 4Y0X ADP 3.32226
72 4XH0 ADP 3.32226
73 4OTH DRN 3.32226
74 4G17 0VN 3.33333
75 2V7O DRN 3.65448
76 4UWH JXM 3.65448
77 5U6C 7YS 3.65448
78 6G34 5ID 3.65448
79 2CSN CKI 3.7037
80 1ION ADP 3.7037
81 4AU8 Z3R 3.71622
82 4NST AF3 3.73134
83 2YAK OSV 3.85965
84 5LX9 OLB 3.87324
85 2IF8 ADP 3.98671
86 3ALN ANP 3.98671
87 2B56 U5P 3.98671
88 2F2U M77 3.98671
89 6GN6 MAL 3.98671
90 1ZDQ MSM 3.98671
91 5CKW ANP 3.99113
92 5Y80 IRE 4.05405
93 2YAB AMP 4.31894
94 2BPM 529 4.31894
95 2BP1 FLC 4.31894
96 5WO4 B7V 4.31894
97 6GUE FB8 4.47761
98 4BCN T9N 4.58015
99 4BCQ TJF 4.58015
100 4CFU 2WC 4.58015
101 6CGZ HL6 4.60993
102 5FI4 5XV 4.64396
103 4R78 AMP 4.65116
104 3CY2 MB9 4.65116
105 3RE4 TO1 4.65116
106 3HYW DCQ 4.65116
107 4N70 2HX 4.65116
108 4WOV 3SM 4.65116
109 5LMK 6ZK 4.65116
110 2ZV2 609 4.69799
111 4OKE AMP 4.7619
112 5N26 CPT 4.94506
113 3VPD ANP 4.98221
114 3F7Z 34O 4.98339
115 4NM5 ADP 4.98339
116 3ORK AGS 4.98339
117 4IX4 ADP 4.98339
118 2JLD AG1 4.98339
119 2AQX ATP 5.19031
120 2A19 ANP 5.28169
121 1M0W ANP 5.31561
122 5DMZ ADP 5.31561
123 6CMJ F6J 5.31561
124 1XJD STU 5.31561
125 6C1S EFV 5.31561
126 3PN1 IVH 5.31561
127 4BHN BH9 5.31561
128 1Q8Y ADP 5.31561
129 4JR7 GNP 5.64784
130 3GGF GVD 5.64784
131 3W5N RAM 5.64784
132 1UNH IXM 5.76923
133 6EZ6 C5Z 5.98007
134 5OMY 9YE 5.98007
135 3PE2 E1B 5.98007
136 3LXN MI1 5.98007
137 4XDY HIO 5.98007
138 2PVN P63 5.98007
139 5AE9 OKO 5.98007
140 1PHK ATP 6.04027
141 3K5I ADP 6.31229
142 3FHR P4O 6.31229
143 4NW6 2NS 6.31229
144 6BJO DUY 6.4
145 4Q5H ANP 6.41026
146 2VZ6 FEF 6.64452
147 4X7Q 3YR 6.64452
148 6A1G 9OL 6.64452
149 5LPZ ADP 6.64452
150 4OH4 ANP 6.64452
151 5YF9 NIO 6.64452
152 5LPB ADP 6.75676
153 1W2D ADP 6.79245
154 1W2D 4IP 6.79245
155 4WNP 3RJ 6.96864
156 3DLS ADP 6.97674
157 2VN9 GVD 6.97674
158 6BFN DL1 6.97674
159 4LRJ ANP 7.10059
160 6GZD LCI 7.30897
161 2R5T ANP 7.5067
162 2PYW ADP 7.6412
163 2B9J ADP 7.6412
164 2B9F ADP 7.6412
165 2B9I ADP 7.6412
166 3X01 AMP 7.97342
167 3O0G 3O0 8.05369
168 4V3I ASP LEU THR ARG PRO 8.17121
169 3KU0 ADE 8.36653
170 4WW7 AMP 8.42912
171 5W7B MYR 8.51064
172 4FG8 ATP 8.63787
173 4BFM ANP 8.63787
174 5TDF ADP 8.9701
175 5UGW GSH 9.14286
176 1T0S BML 9.63455
177 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 9.96678
178 2JDR L20 9.96678
179 4IDT T28 10.299
180 5OES ADP 10.6312
181 5NNT DPV 10.8108
182 2H8H H8H 11.2957
183 1Y57 MPZ 11.2957
184 3V4S ATP 11.6279
185 3IDB ANP 11.8012
186 4U98 ACP 12.6246
187 3W0O ADP 13.6213
188 3W0O HY0 13.6213
189 2BKK ADP 13.6364
190 3TM0 B31 13.6882
191 3TM0 ANP 13.6882
192 6CGD GNP 15.2824
193 6CGD AKN 15.2824
194 3FHI ANP 16.8831
195 3NOJ PYR 17.2269
196 4H3Q ANP 17.9402
197 3ZRM ZRM 18.75
198 3RV5 DXC 20.2247
199 4DFU QUE 32.2259
200 4DFB KAN 32.2259
201 4DFU KAN 32.2259
202 5C4L SIS 32.5581
203 5C4L 4XR 32.5581
204 3TDV GDP 39.8671
Pocket No.: 3; Query (leader) PDB : 5IGI; Ligand: ZIT; Similar sites found with APoc: 7
This union binding pocket(no: 3) in the query (biounit: 5igi.bio2) has 38 residues
No: Leader PDB Ligand Sequence Similarity
1 4ZS4 ATP 0.996678
2 3PDT ADP 1.09091
3 2YW2 ATP 2.32558
4 4UXL 5P8 2.65781
5 2PUL ACP 4.65116
6 1Q8Y ADE 5.31561
7 5AOV GLV 17.9402
Pocket No.: 4; Query (leader) PDB : 5IGI; Ligand: ZIT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5igi.bio2) has 38 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 5IGI; Ligand: GMP; Similar sites found with APoc: 6
This union binding pocket(no: 5) in the query (biounit: 5igi.bio2) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 4ZS4 ATP 0.996678
2 3PDT ADP 1.09091
3 2YW2 ATP 2.32558
4 2PUL ACP 4.65116
5 1Q8Y ADE 5.31561
6 5AOV GLV 17.9402
Pocket No.: 6; Query (leader) PDB : 5IGI; Ligand: GMP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 5igi.bio2) has 37 residues
No: Leader PDB Ligand Sequence Similarity
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