-->
Receptor
PDB id Resolution Class Description Source Keywords
5X9D 2.1 Å EC: 1.1.1.3 CRYSTAL STRUCTURE OF HOMOSERINE DEHYDROGENASE IN COMPLEX WIT CYSTEINE AND NAD SULFOLOBUS TOKODAII (STRAIN DSM 16993 10545 / NBRC 100140 / 7) OXIDOREDUCTASE COMPLEX INHIBITOR
Ref.: INHIBITION OF HOMOSERINE DEHYDROGENASE BY FORMATION CYSTEINE-NAD COVALENT COMPLEX SCI REP V. 8 5749 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
80F A:501;
Valid;
none;
submit data
784.583 C24 H34 N8 O16 P2 S c1nc(...
TLA A:502;
Invalid;
none;
submit data
150.087 C4 H6 O6 [C@@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5X9D 2.1 Å EC: 1.1.1.3 CRYSTAL STRUCTURE OF HOMOSERINE DEHYDROGENASE IN COMPLEX WIT CYSTEINE AND NAD SULFOLOBUS TOKODAII (STRAIN DSM 16993 10545 / NBRC 100140 / 7) OXIDOREDUCTASE COMPLEX INHIBITOR
Ref.: INHIBITION OF HOMOSERINE DEHYDROGENASE BY FORMATION CYSTEINE-NAD COVALENT COMPLEX SCI REP V. 8 5749 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5X9D - 80F C24 H34 N8 O16 P2 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5X9D - 80F C24 H34 N8 O16 P2 S c1nc(c2c(n....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 6A0T - HSE C4 H9 N O3 C(CO)[C@@H....
2 6A0U - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 6A0S Kd = 1.6 uM NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
4 5X9D - 80F C24 H34 N8 O16 P2 S c1nc(c2c(n....
5 4XB2 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
6 4XB1 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 80F; Similar ligands found: 232
No: Ligand ECFP6 Tc MDL keys Tc
1 80F 1 1
2 NAI 0.65 0.925926
3 EAD 0.636364 0.915663
4 P1H 0.617647 0.894118
5 AP0 0.612903 0.891566
6 A2D 0.596154 0.864198
7 NAJ PZO 0.59542 0.869048
8 NAJ PYZ 0.577778 0.829545
9 NAX 0.571429 0.939024
10 6V0 0.571429 0.914634
11 TXD 0.571429 0.857143
12 BA3 0.570093 0.864198
13 TXE 0.566929 0.879518
14 AP5 0.564815 0.864198
15 B4P 0.564815 0.864198
16 ADP 0.564815 0.841463
17 ATP 0.563636 0.841463
18 HEJ 0.563636 0.841463
19 AN2 0.559633 0.831325
20 5FA 0.558559 0.841463
21 APR 0.558559 0.864198
22 AQP 0.558559 0.841463
23 AR6 0.558559 0.864198
24 SRP 0.556522 0.878049
25 5AL 0.552632 0.853659
26 A1R 0.550847 0.835294
27 AMO 0.550847 0.901235
28 ACP 0.54955 0.843373
29 0WD 0.548872 0.914634
30 A22 0.547009 0.853659
31 DG1 0.546763 0.914634
32 1DG 0.546763 0.914634
33 AT4 0.545455 0.855422
34 ANP 0.54386 0.821429
35 ACQ 0.54386 0.843373
36 M33 0.540541 0.831325
37 CA0 0.540541 0.865854
38 AD9 0.539823 0.821429
39 AGS 0.539823 0.845238
40 SAP 0.539823 0.845238
41 ADJ 0.537879 0.872093
42 NDP 0.537879 0.914634
43 ADQ 0.537815 0.865854
44 4AD 0.537815 0.890244
45 50T 0.535714 0.809524
46 ME8 0.532787 0.83908
47 YAP 0.532258 0.890244
48 PRX 0.530973 0.77907
49 6YZ 0.529915 0.843373
50 8QN 0.529412 0.853659
51 OAD 0.528926 0.865854
52 ADX 0.526786 0.786517
53 LAD 0.52459 0.837209
54 AMP 0.523364 0.817073
55 A 0.523364 0.817073
56 UP5 0.523077 0.890244
57 ATF 0.521368 0.811765
58 AHX 0.520661 0.847059
59 PTJ 0.520325 0.804598
60 NB8 0.520325 0.869048
61 3OD 0.520325 0.865854
62 FA5 0.52 0.901235
63 F2R 0.518519 0.820225
64 9X8 0.516393 0.86747
65 4TC 0.515152 0.891566
66 PAJ 0.512397 0.816092
67 A3R 0.512397 0.835294
68 WAQ 0.512195 0.835294
69 NXX 0.51145 0.878049
70 DND 0.51145 0.878049
71 00A 0.508197 0.835294
72 TXA 0.508065 0.855422
73 APC 0.504348 0.833333
74 OOB 0.504132 0.876543
75 25L 0.504 0.853659
76 48N 0.503817 0.847059
77 DQV 0.5 0.876543
78 TYM 0.496241 0.901235
79 OMR 0.496241 0.788889
80 B5M 0.496063 0.845238
81 BIS 0.496 0.793103
82 ABM 0.495495 0.797619
83 YLP 0.492424 0.8
84 XAH 0.492188 0.797753
85 25A 0.491803 0.841463
86 5SV 0.491803 0.744444
87 TAT 0.491525 0.855422
88 T99 0.491525 0.855422
89 TYR AMP 0.488372 0.86747
90 9SN 0.488189 0.825581
91 PR8 0.488 0.827586
92 AP2 0.486726 0.833333
93 A12 0.486726 0.833333
94 1ZZ 0.484127 0.777778
95 FYA 0.484127 0.853659
96 DLL 0.483871 0.876543
97 DAL AMP 0.483607 0.831325
98 5X8 0.482759 0.768293
99 YLA 0.481752 0.820225
100 YLB 0.481481 0.8
101 YLC 0.481481 0.83908
102 AFH 0.480916 0.837209
103 3UK 0.48 0.865854
104 9ZD 0.479675 0.813953
105 9ZA 0.479675 0.813953
106 AYB 0.478261 0.791209
107 CNA 0.478261 0.878049
108 NZQ 0.478261 0.926829
109 SRA 0.477477 0.821429
110 B5V 0.47619 0.855422
111 ADV 0.474576 0.855422
112 RBY 0.474576 0.855422
113 AU1 0.474138 0.821429
114 COD 0.471429 0.793478
115 NPW 0.471014 0.927711
116 139 0.471014 0.870588
117 T5A 0.471014 0.905882
118 7MD 0.469697 0.83908
119 NAQ 0.468966 0.804598
120 TXP 0.467626 0.847059
121 A4P 0.467153 0.842697
122 GAP 0.466667 0.821429
123 4UV 0.465649 0.91358
124 SON 0.465517 0.855422
125 ADP PO3 0.462185 0.817073
126 G3A 0.462121 0.825581
127 B5Y 0.461538 0.845238
128 NAD 0.460993 0.853659
129 NMN AMP PO4 0.460993 0.890244
130 UPA 0.459854 0.879518
131 G5P 0.458647 0.825581
132 ARG AMP 0.458647 0.788889
133 ADP BMA 0.456693 0.843373
134 GTA 0.455224 0.797753
135 A3D 0.454545 0.843373
136 IOT 0.453237 0.791209
137 LAQ 0.451852 0.818182
138 A2R 0.451613 0.853659
139 MAP 0.448 0.802326
140 4UU 0.447761 0.91358
141 NDE 0.447368 0.833333
142 ADP ALF 0.447154 0.761364
143 ALF ADP 0.447154 0.761364
144 N0B 0.445946 0.840909
145 SFG 0.445378 0.73494
146 NJP 0.443662 0.845238
147 VO4 ADP 0.443548 0.809524
148 ADP VO4 0.443548 0.809524
149 NAE 0.442177 0.823529
150 2A5 0.441667 0.8
151 FB0 0.441558 0.75
152 EEM 0.439024 0.681319
153 7MC 0.438849 0.820225
154 ATR 0.438017 0.817073
155 DZD 0.4375 0.837209
156 GA7 0.437037 0.833333
157 7D4 0.436975 0.767442
158 ZID 0.436242 0.843373
159 YLY 0.435374 0.791209
160 MYR AMP 0.435115 0.758242
161 62F 0.434783 0.797753
162 4UW 0.434783 0.880952
163 SAH 0.434426 0.75
164 SAI 0.434426 0.72093
165 NA7 0.434109 0.833333
166 TAD 0.433824 0.858824
167 5AS 0.432203 0.708333
168 SSA 0.432 0.782609
169 S7M 0.432 0.7
170 AF3 ADP 3PG 0.431655 0.795455
171 XNP 0.430556 0.892857
172 LMS 0.429825 0.747253
173 LSS 0.429688 0.747368
174 DSZ 0.429688 0.802198
175 BT5 0.427586 0.831461
176 7D3 0.42735 0.767442
177 NVA LMS 0.426357 0.739583
178 SA8 0.42623 0.696629
179 PAP 0.42623 0.829268
180 FNK 0.425926 0.826087
181 M24 0.425676 0.806818
182 YSA 0.425373 0.782609
183 TSB 0.425197 0.76087
184 53H 0.425197 0.726316
185 5CA 0.425197 0.782609
186 ITT 0.425 0.795181
187 A5A 0.424 0.75
188 LEU LMS 0.423077 0.739583
189 AOC 0.422414 0.73494
190 BTX 0.42069 0.820225
191 SMM 0.420635 0.695652
192 A A 0.419847 0.819277
193 GSU 0.419847 0.782609
194 SFD 0.41875 0.757576
195 NSS 0.418605 0.782609
196 54H 0.417323 0.734043
197 52H 0.417323 0.726316
198 VMS 0.417323 0.734043
199 JB6 0.416667 0.857143
200 6AD 0.416 0.837209
201 NDC 0.414013 0.804598
202 ODP 0.413793 0.858824
203 G5A 0.41129 0.763441
204 HFD 0.41129 0.802326
205 RAB 0.411215 0.731707
206 XYA 0.411215 0.731707
207 ADN 0.411215 0.731707
208 AHZ 0.410072 0.797753
209 KAA 0.409091 0.739583
210 FDA 0.408805 0.833333
211 3AT 0.408 0.841463
212 0UM 0.407692 0.688889
213 ATP A A A 0.407407 0.829268
214 LPA AMP 0.407143 0.797753
215 6FA 0.40625 0.8
216 AR6 AR6 0.405797 0.841463
217 PPS 0.404762 0.766667
218 7D5 0.403509 0.744186
219 AV2 0.401575 0.776471
220 K15 0.401515 0.673913
221 AMP DBH 0.40146 0.821429
222 WSA 0.401408 0.791209
223 AMP NAD 0.401361 0.853659
224 4TA 0.401361 0.872093
225 FAS 0.401235 0.808989
226 FAD 0.401235 0.808989
227 F2N 0.401163 0.835165
228 A3P 0.4 0.817073
229 5CD 0.4 0.698795
230 AVV 0.4 0.804598
231 3DH 0.4 0.694118
232 A2P 0.4 0.804878
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5X9D; Ligand: 80F; Similar sites found with APoc: 960
This union binding pocket(no: 1) in the query (biounit: 5x9d.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 2CHT TSA None
2 5C2N NAG None
3 1SNY NAP None
4 5THQ NDP 1.10294
5 2Q1S NAI 1.31579
6 1U7T TDT 1.53257
7 1U7T NAD 1.53257
8 4NBW NAD 1.55642
9 2A92 NAI 1.64474
10 4PLG OXM 1.64474
11 4PLG NAI 1.64474
12 1KEV NDP 1.64474
13 2FZW NAD 1.64474
14 1FEC FAD 1.64474
15 5Y77 FAD 1.64474
16 5VKT NAP 1.64474
17 1BXK NAD 1.64474
18 2V6G NAP 1.64474
19 5NII FAD 1.64474
20 5F5N NAD 1.7301
21 1LUA NAP 1.74216
22 3OIG NAD 1.8797
23 2ZAT NAP 1.92308
24 6CI9 NAP 1.9305
25 1OAA OAA 1.9305
26 1UP7 NAD 1.97368
27 1GR0 NAD 1.97368
28 1YKF NAP 1.97368
29 1PZG A3D 1.97368
30 5ZI2 NAD 1.97368
31 4PIV NDP 1.97368
32 5ZI2 ADP 1.97368
33 4JBI NDP 1.97368
34 1H2B NAJ 1.97368
35 2Y6Q FAD 1.97368
36 5MSO NAP 1.97368
37 4ZRN UPG 1.97368
38 1EQ2 NAP 1.97368
39 2X6T NAP 1.97368
40 5MIT NAP 1.97368
41 5MIT FAD 1.97368
42 1UDB NAD 1.97368
43 1UDB UFG 1.97368
44 3HB5 NAP 1.97368
45 1RJW ETF 1.97368
46 3FSY SCA 1.97368
47 4CTA ATP 1.97368
48 4ZRN NAD 1.97368
49 2Y6Q I7T 1.97368
50 5NMX NAP 1.97368
51 1GZ6 NAI 1.97368
52 1ZBQ NAD 1.97368
53 5Y8L HUI 2.0339
54 5Y8L NAD 2.0339
55 3O03 NAP 2.06186
56 2WEI VGG 2.09059
57 3U3U EAH 2.14592
58 2RH4 EMO 2.16606
59 1JA9 NDP 2.18978
60 2QZZ NAP 2.20126
61 2QZZ EMF 2.20126
62 5UC9 MYR 2.21239
63 4EA7 JB2 2.27273
64 4EA7 COA 2.27273
65 1LTH NAD 2.30263
66 3WWX DIA 2.30263
67 3VPH NAD 2.30263
68 2WPF FAD 2.30263
69 1E5Q NDP 2.30263
70 2WPF WPF 2.30263
71 1MO9 FAD 2.30263
72 3VPH OXM 2.30263
73 1MO9 KPC 2.30263
74 5BUK FAD 2.30263
75 4YKG NAD 2.30263
76 1TDF NAP 2.30263
77 3GMB FAD 2.30263
78 4YKG FAD 2.30263
79 5JCM NAD 2.30263
80 5JCM ISD 2.30263
81 5JCM FAD 2.30263
82 5KVS NAP 2.30263
83 3OA2 NAD 2.30263
84 5HXI FAD 2.30263
85 1TDF FAD 2.30263
86 1TJY PAV 2.30263
87 4KCT PYR 2.30263
88 2RAB NAD 2.30263
89 3T95 PAV 2.30263
90 1WDK NAD 2.30263
91 3G5S FAD 2.30263
92 1MXG ACR 2.30263
93 4CYI ATP 2.30263
94 1E1M NAP 2.30263
95 1E1M FAD 2.30263
96 5JE8 NAD 2.31788
97 3DCJ THH 2.32558
98 3ICC NAP 2.35294
99 4ZA2 NAD 2.37154
100 3ORF NAD 2.39044
101 4NBU NAI 2.4
102 1O5I NAD 2.40964
103 4URF NAD 2.41935
104 4QED NAP 2.41935
105 2CVZ NDP 2.42215
106 1N5D NDP 2.43056
107 2AG5 NAD 2.43902
108 1G0N NDP 2.4735
109 1G0N PHH 2.4735
110 5LQ8 GB 2.48227
111 3SJU NDP 2.50896
112 1NBU PH2 2.52101
113 1BDB NAD 2.52708
114 6F9Q NAD 2.57353
115 2GDZ NAD 2.62172
116 3BAZ NAP 2.63158
117 3K5I AIR 2.63158
118 1RM0 D6P 2.63158
119 1RM0 NAI 2.63158
120 5NUF NAD 2.63158
121 5NUE NAD 2.63158
122 1F8G NAD 2.63158
123 1X87 NAD 2.63158
124 3ETG GLU 2.63158
125 5Z21 NAI 2.63158
126 1Y1P NMN AMP PO4 2.63158
127 1DIG NAP 2.63158
128 2Q0L NAP 2.63158
129 3ETG NDP 2.63158
130 2PK3 A2R 2.63158
131 5XWV 8H6 2.63158
132 5XWV NDP 2.63158
133 4TSK NDP 2.63158
134 1E3I CXF 2.63158
135 2IXB NAD 2.63158
136 1PS9 NAP 2.63158
137 5MQ6 NDP 2.63158
138 1P7T PYR 2.63158
139 2Q7V FAD 2.63158
140 1PS9 FAD 2.63158
141 3CTY FAD 2.63158
142 5WJ6 B4A 2.63158
143 5X68 FAD 2.63158
144 4IP7 FLC 2.63158
145 5TWB FAD 2.63158
146 5BVA FAD 2.63158
147 1DIG L37 2.63158
148 2IXB A2G 2.63158
149 3LZW FAD 2.63158
150 2Q0L FAD 2.63158
151 3ETG GTP 2.63158
152 3LZW NAP 2.63158
153 1D8C GLV 2.63158
154 2CUN 3PG 2.63158
155 4EVQ PHB 2.63158
156 1L7E NAI 2.63158
157 4B4U NAP 2.64026
158 1YJQ NAP 2.64026
159 6AA8 NAD 2.64901
160 4B1M FRU FRU 2.7027
161 3F81 STT 2.73224
162 3B1F NAD 2.75862
163 3H4V NAP 2.77778
164 3CH6 NAP 2.7972
165 3CH6 311 2.7972
166 5A4W QCT 2.83019
167 4D42 NAP 2.83688
168 4D42 W0I 2.83688
169 2DT5 NAD 2.8436
170 1HDR NAD 2.86885
171 2BD0 NAP 2.86885
172 2B4Q NAP 2.89855
173 4NBT NAD 2.91667
174 4BAE RWX 2.92683
175 1A5Z NAD 2.96053
176 3GFB NAD 2.96053
177 1KJ8 GAR 2.96053
178 6C4N NAP 2.96053
179 5TC4 NAD 2.96053
180 3NJ4 NAD 2.96053
181 1CF2 NAP 2.96053
182 3NJ4 AFX 2.96053
183 4MP8 MLI 2.96053
184 4MP8 NAD 2.96053
185 5M67 ADE 2.96053
186 1D1T NAD 2.96053
187 1J49 NAD 2.96053
188 5M67 NAD 2.96053
189 4R1S NAP 2.96053
190 3GGO NAI 2.96053
191 3GGO ENO 2.96053
192 1GY8 NAD 2.96053
193 5M67 3D1 2.96053
194 1LVL NAD 2.96053
195 1OC2 NAD 2.96053
196 1OC2 TDX 2.96053
197 5IN4 6CK 2.96053
198 2VUT NAD 2.96053
199 5IN4 GDP 2.96053
200 5IN4 NAP 2.96053
201 1H82 GZZ 2.96053
202 1H82 FAD 2.96053
203 1TI7 NAP 2.96053
204 3O26 NDP 2.96053
205 4D04 FAD 2.96053
206 4D04 NAP 2.96053
207 4J1Q NDP 2.96053
208 3AB1 FAD 2.96053
209 1NM5 NAD 2.96053
210 6AIN FAD 2.96053
211 5TUK FAD 2.96053
212 2Q1W NAD 2.96053
213 2HQM FAD 2.96053
214 4Y85 499 2.96053
215 5N0J FAD 2.96053
216 3AY6 NAI 2.97398
217 3RFV NAI 2.99625
218 3RFV 15L 2.99625
219 2PV7 NAD 3.02013
220 1I36 NAP 3.0303
221 5J75 6GQ 3.0303
222 1E3W NAD 3.06513
223 1GEE NAD 3.06513
224 1E6W NAD 3.07692
225 3VZS CAA 3.11284
226 3VZS NAP 3.11284
227 2NU8 COA 3.125
228 1GEG NAD 3.125
229 2JL1 NAP 3.13589
230 2H6B 3C4 3.2
231 2G5C NAD 3.20285
232 1FL2 FAD 3.22581
233 5U5N NAD 3.22581
234 5Z2L NDP 3.26531
235 2NU5 NAG 3.27869
236 2GUC MAN 3.27869
237 2HYQ MAN MAN 3.27869
238 2NUO BGC 3.27869
239 2GUD MAN 3.27869
240 2GUD BMA 3.27869
241 2HYR BGC GLC 3.27869
242 5O4J PJL 3.28467
243 5O4J SAH 3.28467
244 5O4J 9KH 3.28467
245 5UAV TFB 3.28947
246 4OM8 NAD 3.28947
247 5UAV NDP 3.28947
248 2AQJ TRP 3.28947
249 2AQJ FAD 3.28947
250 5X7Q GLC GLC GLC 3.28947
251 5X7Q GLC GLC GLC GLC 3.28947
252 4GKV NAD 3.28947
253 5Y1G AKB 3.28947
254 5XWC NAP 3.28947
255 5XWC 2IT 3.28947
256 5XWC 8GL 3.28947
257 5Y1G NAD 3.28947
258 1V8B NAD 3.28947
259 1O0S NAI 3.28947
260 4BJZ P3A 3.28947
261 4BJZ FAD 3.28947
262 5L4L NAP 3.28947
263 1R6D DAU 3.28947
264 1R6D NAD 3.28947
265 5G4L NDP 3.28947
266 1J0X NAD 3.28947
267 4IDC NDP 3.28947
268 4IDC 1XX 3.28947
269 1RKX NAD 3.28947
270 4LOO SB4 3.28947
271 3OZ2 FAD 3.28947
272 1N1G BCP 3.28947
273 3F8D FAD 3.28947
274 2E5V FAD 3.28947
275 5JY4 ISC 3.28947
276 5OVL NAP 3.33333
277 2DTJ THR 3.37079
278 5NM7 GLY 3.38346
279 1H5Q NAP 3.39623
280 4OSP NAP 3.42205
281 3H8V ATP 3.42466
282 5OCM NAP 3.43643
283 1NFQ NAI 3.46154
284 1X1T NAD 3.46154
285 4RDH AMP 3.47222
286 4RDI ATP 3.47222
287 5YSS NAD 3.51562
288 1RP0 AHZ 3.52113
289 5H4S RAM 3.52113
290 2DKN NAI 3.52941
291 2Q2V NAD 3.52941
292 2PHR MAN MAN BMA MAN 3.57143
293 5L95 AMP 3.58423
294 3MMH SME 3.59281
295 9LDT NAD 3.61842
296 1C1X NAD 3.61842
297 1BXG NAD 3.61842
298 5Z20 NAI 3.61842
299 1ZH8 NAP 3.61842
300 1F8F NAD 3.61842
301 3WBF NAP 3.61842
302 2CVQ NDP 3.61842
303 9LDB NAD 3.61842
304 3WBF API 3.61842
305 1BW9 NAD 3.61842
306 1UWK URO 3.61842
307 1UWK NAD 3.61842
308 5CAE SIN 3.61842
309 6DNT NAD 3.61842
310 1E7S NAP 3.61842
311 1U8X NAD 3.61842
312 4HNN LYS 3.61842
313 2GV8 NDP 3.61842
314 2YYY NAP 3.61842
315 5A04 NDP 3.61842
316 5CAE COA 3.61842
317 6BWL NAD 3.61842
318 3SQP FAD 3.61842
319 6FHO FAD 3.61842
320 2GVC FAD 3.61842
321 5A04 BGC 3.61842
322 3RNM FAD 3.61842
323 1VQW FAD 3.61842
324 2F5Z FAD 3.61842
325 2VZ6 FEF 3.61842
326 5TUF TDC 3.61842
327 2VTD LKM 3.61842
328 2GV8 FAD 3.61842
329 5TUF FAD 3.61842
330 4YUW 4JU 3.61842
331 3LAD FAD 3.61842
332 6GAR FAD 3.61842
333 1W6U NAP 3.64238
334 1W73 NAP 3.64238
335 1W8D NAP 3.64238
336 2JAP NDP 3.64372
337 2JAH NDP 3.64372
338 5O42 NAD 3.64964
339 5O42 BGC 3.64964
340 5O42 9JW 3.64964
341 4IRX INS 3.71622
342 1XSE NDP 3.72881
343 5D4V SAH 3.73134
344 1JAY NAP 3.77358
345 3BMQ NAP 3.81944
346 3JQA NAP 3.81944
347 5JDI NAP 3.81944
348 3BMO NAP 3.81944
349 3JQ9 NAP 3.81944
350 4CM8 NAP 3.81944
351 3JQ7 NAP 3.81944
352 4CLR NAP 3.81944
353 3JQG NAP 3.81944
354 3JQF NAP 3.81944
355 4CM4 NAP 3.81944
356 4CLO NAP 3.81944
357 5JDC NAP 3.81944
358 5JCJ NAP 3.81944
359 4CMI NAP 3.81944
360 4CM9 NAP 3.81944
361 5K6A NAP 3.81944
362 3BMN NAP 3.81944
363 3JQB NAP 3.81944
364 1V0O INR 3.81944
365 3JQ8 NAP 3.81944
366 4CME NAP 3.81944
367 4JNA FAD 3.82353
368 1U1I NAD 3.82653
369 2AHR NAP 3.861
370 3AFN NAP 3.87597
371 2CUL FAD 3.87931
372 5OVK NDP 3.90625
373 3ABI NAD 3.94737
374 4OOE FOM 3.94737
375 4OOE NDP 3.94737
376 1WPQ NAD 3.94737
377 4BVA NDP 3.94737
378 4ZVV GN0 3.94737
379 2IZ1 ATR 3.94737
380 4ZVV NAD 3.94737
381 4XQC NAD 3.94737
382 5AOV NAP 3.94737
383 2DBZ NAP 3.94737
384 4XQC 13D 3.94737
385 6C4T NA7 3.94737
386 6C4M NAP 3.94737
387 4YT4 FE9 3.94737
388 1KOL NAD 3.94737
389 3DAG FEG 3.94737
390 1I2B USQ 3.94737
391 1I2B UPG 3.94737
392 1I2B NAD 3.94737
393 2C29 DQH 3.94737
394 4BVA T3 3.94737
395 3FPZ AHZ 3.94737
396 2NPX NAD 3.94737
397 5KOX RFP 3.94737
398 5KOX FAD 3.94737
399 2B4R NAD 3.94737
400 4Y9D NAI 3.94737
401 2B4R AES 3.94737
402 3U4C NDP 3.94737
403 1Q9I TEO 3.94737
404 1Q9I FAD 3.94737
405 1YB5 NAP 3.94737
406 2C29 NAP 3.94737
407 4B63 ORN 3.94737
408 4B63 NAP 3.94737
409 4B63 FAD 3.94737
410 5GXU FMN 3.94737
411 3AYI HCI 3.94737
412 3AYI FAD 3.94737
413 3SJ7 NDP 3.96825
414 5N6C NAD 4
415 5T2U NAP 4.03226
416 4RF2 NAP 4.04412
417 5EES NAP 4.04858
418 5L3S G 4.05405
419 5T9E NAP 4.05904
420 4CQM NAP 4.09836
421 1Q7B NAP 4.09836
422 2WD7 NAP 4.10448
423 2VZ0 D64 4.10448
424 2VZ0 NAP 4.10448
425 1IY8 NAD 4.11985
426 5Z2F NAP 4.15094
427 4YAG NAI 4.15225
428 1QCI ADE 4.19847
429 1FNZ A2G 4.21941
430 4E5N NAD 4.27632
431 1V6A TRE 4.27632
432 1LDM NAD 4.27632
433 5X20 NAD 4.27632
434 4L8V NAP 4.27632
435 2NAD NAD 4.27632
436 2ZJ1 ARJ 4.27632
437 1GQ2 NAP 4.27632
438 3V1U NAD 4.27632
439 2ZJ1 NAD 4.27632
440 5BJX NAD 4.27632
441 5BJX UDP 4.27632
442 3C1O NAP 4.27632
443 4EIP FAD 4.27632
444 5MLR GRQ 4.27632
445 5MLR NAP 4.27632
446 5JCA NDP 4.27632
447 3UOY NAP 4.27632
448 3UOY FAD 4.27632
449 1RPN NDP 4.27632
450 5EVY FAD 4.27632
451 5JCA FAD 4.27632
452 1K3T BRZ 4.27632
453 5BRT CH9 4.27632
454 4NTC FAD 4.27632
455 3KLJ FAD 4.27632
456 5BRT FAD 4.27632
457 5VSM MET 4.27632
458 1YQD NAP 4.27632
459 1GTE FAD 4.27632
460 4EIP K2C 4.27632
461 5WS9 OXL 4.27632
462 5K0A FAD 4.27632
463 3FWN ATR 4.27632
464 4Z0H NAD 4.27632
465 2BCG GDP 4.36893
466 5T9F TYR 4.42804
467 5T9F NAP 4.42804
468 3NUG NAD 4.45344
469 1PR9 NAP 4.5082
470 3D3W NAP 4.5082
471 1VHZ APR 4.54545
472 5OEC GDP 4.56853
473 4D3F NAP 4.60526
474 1UXG FUM 4.60526
475 1UXG NAD 4.60526
476 1MUU NAD 4.60526
477 1GZ4 ATP 4.60526
478 1OMO NAD 4.60526
479 2GZ3 NAP 4.60526
480 5DN9 NAD 4.60526
481 5A1T OXM 4.60526
482 4M5P MLA 4.60526
483 1TB4 PEJ 4.60526
484 5KKA 6V0 4.60526
485 5A1T NAI 4.60526
486 6F3N ADN 4.60526
487 6F3N NAD 4.60526
488 6F3M NAD 4.60526
489 3KB6 NAD 4.60526
490 3KO8 NAD 4.60526
491 3UCL NAP 4.60526
492 1X7D ORN 4.60526
493 2JHF NAD 4.60526
494 1MV8 NAD 4.60526
495 5MZI FAD 4.60526
496 5MZI FYK 4.60526
497 1MUU SUC 4.60526
498 1PN0 FAD 4.60526
499 3UCL CYH 4.60526
500 3UCL FAD 4.60526
501 1PN0 IPH 4.60526
502 1X7D NAD 4.60526
503 1C0I FAD 4.60526
504 1C0I BE2 4.60526
505 6ER9 FAD 4.60526
506 2VVL FAD 4.60526
507 3FHI ANP 4.60526
508 2VVM FAD 4.60526
509 6ER9 NAP 4.60526
510 3FG2 FAD 4.60526
511 5B4T 3HR 4.61538
512 5B4T NAD 4.61538
513 2VT3 ATP 4.65116
514 3WXB NDP 4.6595
515 3Q3C NAD 4.68227
516 1ZS6 ADP 4.73373
517 5N2I NAP 4.74138
518 1J5P NAD 4.74308
519 2Q46 NAP 4.74308
520 1P77 ATR 4.77941
521 5OOH NAP 4.85437
522 5OOH 9ZZ 4.85437
523 2CHG ANP 4.86726
524 4XJ7 ADN 4.86891
525 3OJO NAD 4.87239
526 5YRG BGC GLC 4.92958
527 5YRJ BGC GLC 4.92958
528 2CDU ADP 4.93421
529 1CER NAD 4.93421
530 1QMG APX 4.93421
531 5Z75 NAD 4.93421
532 3L4S NAD 4.93421
533 3L4S 3PG 4.93421
534 5AYV KPL 4.93421
535 1LLU NAD 4.93421
536 5W3K NDP 4.93421
537 5W3K 9TY 4.93421
538 4J36 FAD 4.93421
539 4J36 1HR 4.93421
540 4PVD NDP 4.93421
541 5J5Z FAD 4.93421
542 5C9P FUC 4.93421
543 5AYV NAP 4.93421
544 4UZI IMD 4.93421
545 5J60 FAD 4.93421
546 4EUE NAI 4.93421
547 4R8L ASP 4.93421
548 1OFL NGK GCD 4.93421
549 5JY6 NAD 4.93421
550 5ZYN FAD 4.93421
551 4EDF UPG 4.93421
552 5L4S NAP 4.93421
553 5L4S 6KX 4.93421
554 5CG1 NAD BBN 4.93421
555 1N9G NAP 4.93421
556 1LAN LEU 4.93421
557 4M52 FAD 4.93421
558 3AD8 NAD 5.05051
559 4D79 ATP 5.07246
560 4O0L NDP 5.09091
561 1KYQ NAD 5.10949
562 3RJ5 NAD 5.11811
563 1AE1 NAP 5.12821
564 2OOR NAD 5.17241
565 4JWK CTN 5.18135
566 3QWI NAP 5.18518
567 3QWI CUE 5.18518
568 2JAJ D20 5.19031
569 1Z0N BCD 5.20833
570 4J7U NAP 5.20833
571 4J7U YTZ 5.20833
572 1GUZ NAD 5.26316
573 1VKO NAD 5.26316
574 4KOA NDP 5.26316
575 1DSS NAD 5.26316
576 5O9F 9ON 5.26316
577 5O9F NAD 5.26316
578 2GLX NDP 5.26316
579 3S5W NAP 5.26316
580 1GV0 NAD 5.26316
581 1KEW NAD 5.26316
582 5U8U FAD 5.26316
583 4K5S FAD 5.26316
584 1KEW TYD 5.26316
585 1U3U BNF 5.26316
586 1U3U NAD 5.26316
587 5K4W THR 5.26316
588 2NVK NAP 5.26316
589 3WLE NAD 5.26316
590 1R37 NAD 5.26316
591 3S5W FAD 5.26316
592 4K5S PM0 5.26316
593 5K4W NAI 5.26316
594 2QA1 FAD 5.26316
595 5H81 NAP 5.26316
596 4WA2 SIA GAL NAG 5.26316
597 3EJW PAV 5.26316
598 3IHG FAD 5.26316
599 3K7M FAD 5.26316
600 5ZZ6 NAD 5.28846
601 5ZZ6 ADP 5.28846
602 1Z6Z NAP 5.31915
603 4Q9N NAI 5.36913
604 3GDH MGP 5.39419
605 1E6E FAD 5.46875
606 5WQP NCA 5.55556
607 5WQP NAP 5.55556
608 2HJR APR 5.59211
609 5LD5 NAD 5.59211
610 3V1Y NAD 5.59211
611 4RQU NAD 5.59211
612 5GUD 2IT 5.59211
613 4UP3 NDP 5.59211
614 5GUD NDP 5.59211
615 1P0F NAP 5.59211
616 3A9B BGC 5.59211
617 3LU1 NAD 5.59211
618 5CX8 3DO 5.59211
619 4YRY NAD 5.59211
620 5GUD CIT 5.59211
621 2ZXI FAD 5.59211
622 2IID PHE 5.59211
623 2IID FAD 5.59211
624 4UP3 FAD 5.59211
625 5XLA SIA 5.59211
626 4YRY FAD 5.59211
627 5KMS NAD 5.59211
628 5TS5 FAD 5.59211
629 2EWM NAD 5.62249
630 4FBL SPD 5.69395
631 5OJL TXP 5.7047
632 5JVB 2PO 5.71429
633 2F1K NAP 5.73477
634 3LN9 FLC 5.7554
635 5FEU NAP 5.84192
636 1SOW NAD 5.92105
637 2GSD NAD 5.92105
638 1N7G NDP 5.92105
639 1N7G GDR 5.92105
640 2XVE FAD 5.92105
641 1GAD NAD 5.92105
642 4NTD FAD 5.92105
643 2Z3Y F2N 5.92105
644 2WME NAP 5.92105
645 1FWV SGA MAG FUC 5.97015
646 2DTX BMA 6.06061
647 1EDO NAP 6.14754
648 1VL0 NAI 6.16438
649 2BKA NDP 6.19835
650 3TN7 NJP 6.22568
651 2D2I NAP 6.25
652 1X14 NAD 6.25
653 2HMT NAI 6.25
654 1HYE NAP 6.25
655 6CEP NAD 6.25
656 3HAD NAD 6.25
657 6CEP OXM 6.25
658 3B1J NAD 6.25
659 1PL6 572 6.25
660 2VYN NAD 6.25
661 5VN0 NAI 6.25
662 2YVF FAD 6.25
663 2YVF NAD 6.25
664 1PL6 NAD 6.25
665 3B20 NAD 6.25
666 4CNK FAD 6.25
667 2RGJ FAD 6.25
668 5VN0 FAD 6.25
669 3CGD COA 6.25
670 3CGD FAD 6.25
671 3CGD NAD 6.25
672 4J56 FAD 6.25
673 2DKH FAD 6.25
674 5GZZ GSH 6.25
675 4Y1B NAP 6.25
676 6FQZ 6PG 6.25
677 4FN4 NAD 6.29921
678 3ZV6 4HB 6.40569
679 3ZV6 NAD 6.40569
680 2YVJ NAI 6.42202
681 5U5G NAP 6.44068
682 3ICS ADP 6.57895
683 3ICT ADP 6.57895
684 4PLT NAI 6.57895
685 4PLT OXM 6.57895
686 1YS4 NAP 6.57895
687 3ULK NDP 6.57895
688 3CMC NAD 6.57895
689 3A06 FOM 6.57895
690 2VHW NAI 6.57895
691 3A06 NDP 6.57895
692 1VJT NAD 6.57895
693 2B5W NAP 6.57895
694 4TQG NDP 6.57895
695 4G5H NAP 6.57895
696 4G5H UD7 6.57895
697 1VCO GLN 6.57895
698 4A0S NAP 6.57895
699 5G3U FDA 6.57895
700 3A28 NAD 6.58915
701 5FFF NAP 6.61479
702 5KAX RHQ 6.62651
703 5TQZ GLC 6.66667
704 1DS6 GDP 6.66667
705 2WSB NAD 6.69291
706 5GWT NAD 6.83453
707 5GWT SIN 6.83453
708 1SQL GUN 6.84932
709 1PJS NAD 6.90789
710 1HYH NAD 6.90789
711 3T31 DCQ 6.90789
712 3T31 FAD 6.90789
713 1LJ8 NAD 6.90789
714 5MDH NAD 6.90789
715 1SAY PYR 6.90789
716 1M2W NAD 6.90789
717 6EL3 NAP 6.90789
718 6FP4 E1T 6.90789
719 2WET FAD 6.90789
720 2GMH FAD 6.90789
721 6FP4 FAD 6.90789
722 1QO8 FAD 6.90789
723 4BV6 FAD 6.90789
724 4MDH NAD 6.90789
725 3QTP 2PG 6.90789
726 2HK9 ATR 6.90909
727 2HK9 NAP 6.90909
728 1VI2 NAD 7
729 1P1C SAH 7.03518
730 1LC3 NAD 7.14286
731 2ZL4 ALA ALA ALA ALA 7.14286
732 6D2O 4MZ 7.17703
733 2ZX2 RAM 7.17949
734 3T5G GDP 7.18232
735 5BSH PRO 7.22022
736 2AG8 NAP 7.22433
737 1LDN NAD 7.23684
738 1HKU NAD 7.23684
739 4KP7 NAP 7.23684
740 4KP7 1UQ 7.23684
741 4OPC PGT 7.23684
742 4OPC FDA 7.23684
743 5UR0 NAD 7.23684
744 3E1T FAD 7.23684
745 3WQQ NDP 7.23684
746 3WQQ IB3 7.23684
747 1HDG NAD 7.23684
748 4XDZ NDP 7.23684
749 3GD4 FAD 7.23684
750 2R00 OEG 7.23684
751 3GD4 NAD 7.23684
752 4JJF FE9 7.23684
753 1GET NAP 7.23684
754 1GET FAD 7.23684
755 4FWE FAD 7.23684
756 4JJF N2I 7.23684
757 4GUT FAD 7.25806
758 4GUS FAD 7.25806
759 1NPD NAD 7.29167
760 3WV8 ATP 7.33945
761 1C3V NDP 7.34694
762 1C3V PDC 7.34694
763 5XKR BZE 7.54717
764 6BII NAP 7.56579
765 5GZ6 NDP 7.56579
766 1Q0H NDP 7.56579
767 5GZ6 7C3 7.56579
768 1Q0H FOM 7.56579
769 5E4R NAP 7.56579
770 5XVH NAP 7.56579
771 1NVM NAD 7.56579
772 1RM4 NDP 7.56579
773 6A3J NAI 7.56579
774 3A4V PYR 7.56579
775 3A4V NAD 7.56579
776 6A3J SOE 7.56579
777 4KVL PLM 7.56579
778 5EOW FAD 7.56579
779 2PZM UDP 7.56579
780 2PZM NAD 7.56579
781 2C7G FAD 7.56579
782 4U8P FDA 7.56579
783 4U8P UDP 7.56579
784 1O6Z NAD 7.59076
785 2CFC NAD 7.6
786 4BCM T7Z 7.6412
787 4HXY NDP 7.76256
788 4E13 NAD 7.77385
789 5VYQ FON 7.84314
790 4R5M NAP 7.89474
791 2DFV NAD 7.89474
792 4R5M 4NO 7.89474
793 2YY7 NAD 7.89474
794 4XYB NDP 7.89474
795 4XDY NAI 7.89474
796 5O98 NAP 7.89474
797 3ZNN FAD 7.89474
798 3ZNN 4WL 7.89474
799 1XF1 CIT 7.89474
800 5UAO FAD 7.94824
801 3ITJ CIT 7.98817
802 1CBK ROI 8.125
803 3CIF NAD 8.22368
804 2O4C NAD 8.22368
805 1V59 NAD 8.22368
806 5N6N SUC 8.22368
807 3WMX NAD 8.22368
808 3CIF G3H 8.22368
809 1ORR NAD 8.22368
810 1V59 FAD 8.22368
811 2CDC XYP 8.22368
812 1XHC FAD 8.22368
813 2CDC XYS 8.22368
814 1Z45 NAD 8.22368
815 2CDC NAP 8.22368
816 3NGL NAP 8.33333
817 1ZEM NAD 8.39695
818 4YSX FAD 8.51064
819 4DPL NAP 8.55263
820 1DJN ADP 8.55263
821 1O94 ADP 8.55263
822 1BZL GCG 8.55263
823 1B8U OAA 8.55263
824 1BZL FAD 8.55263
825 2GN4 UD1 8.55263
826 4KQW NAP 8.55263
827 2GN4 NDP 8.55263
828 3OID NDP 8.55263
829 1ZK7 FAD 8.55263
830 1B8U NAD 8.55263
831 4B7X NAP 8.55263
832 6BFN DL1 8.55263
833 5WGR FAD 8.55263
834 1DRV A3D 8.79121
835 5CSS G3P 8.84956
836 1T26 NAI 8.88158
837 1T26 GBD 8.88158
838 2I3G NAP 8.88158
839 1F06 2NP 8.88158
840 1F06 NDP 8.88158
841 2C5A GDC 8.88158
842 2C5A NAD 8.88158
843 2FR1 NDP 8.88158
844 1Z82 G3H 8.88158
845 1Z82 NDP 8.88158
846 4CJX NAP 8.88158
847 3AB4 LYS 8.88158
848 4ITU 1HS 8.92193
849 4ITU NAI 8.92193
850 4GLL NAD 9.21053
851 4HE2 AMP 9.21053
852 5EIN NAP 9.25926
853 1JNR FAD 9.33333
854 1ZQ9 SAM 9.47368
855 4ZGS NAD 9.53947
856 1SC6 NAD 9.53947
857 4W6Z 8ID 9.53947
858 5ODQ FAD 9.53947
859 5FI3 NAP 9.53947
860 5MBX FAD 9.53947
861 5MBX SP5 9.53947
862 4W6Z ETF 9.53947
863 1VM6 NAD 9.64912
864 1WP4 NDP 9.68858
865 4FC7 NAP 9.74729
866 4FC7 COA 9.74729
867 3OND ADN 9.86842
868 3OND NAD 9.86842
869 1H3F TYE 9.86842
870 2QRK AMP 9.89848
871 4AP9 1PS 9.95025
872 1NC4 DOF 9.95475
873 1NC2 DOE 9.95475
874 1LSS NAD 10
875 1V2G OCA 10
876 2GAG NAD 10.101
877 3O9Z NAD 10.1974
878 3O9Z AKG 10.1974
879 4TXI FAD 10.1974
880 2BRY FAD 10.1974
881 1XKV ATP 10.1974
882 2AE2 PTO 10.3846
883 2AE2 NAP 10.3846
884 3H9E NAD 10.5263
885 3TD3 GLY 10.5691
886 2EV9 SKM 10.6464
887 2EV9 NAP 10.6464
888 4JK3 NAD 10.8108
889 4J4H 1J1 10.8108
890 4J4H NAI 10.8108
891 4QBK 3NZ 10.8247
892 5TOW ADN 10.8553
893 5TOW NAI 10.8553
894 1OBB NAD 10.8553
895 1D4D FAD 10.8553
896 5O2J 2PO 10.989
897 3EW2 BTN 11.1111
898 5GSN FAD 11.1842
899 5GSN NAP 11.1842
900 3L9W AMP 11.1842
901 5GSN MMZ 11.1842
902 3L9W GSH 11.1842
903 1FK8 NAD 11.284
904 5YAP NAI 11.5132
905 5YAP 8S0 11.5132
906 5EPO NAP 11.8321
907 5EPO TUD 11.8321
908 1DLJ NAI 11.8421
909 1DLJ UGA 11.8421
910 4EMI NAD 11.8421
911 4EMJ FAD 11.8421
912 4EMI FAD 11.8421
913 2HIM ASN 11.8421
914 4YCA NDP 11.9048
915 1JG3 ADN 11.9149
916 4II2 ATP 12.0482
917 4O1M NAD 12.1711
918 4TM3 FAD 12.1711
919 3NOJ PYR 12.1849
920 3QV1 NAD 12.1951
921 1SC3 MLI 12.5
922 3TWO NDP 12.5
923 1NVT NAP 12.5436
924 5GT9 NAP 12.5475
925 2NGR GDP 13.089
926 2GCG NDP 13.1579
927 1WAP TRP 13.3333
928 5YEC ATP 13.4868
929 1QAW TRP 13.5135
930 5A96 GTP 13.6546
931 3UW5 MAA CHG PRO 0DQ 13.7931
932 5YU3 PRO 13.8158
933 5YU3 NAD 13.8158
934 1VL8 NAP 14.2322
935 1EK6 NAI 14.4737
936 1EK6 UPG 14.4737
937 1NYT NAP 14.7601
938 3WGT FAD 14.8026
939 1LNX URI 14.8148
940 1YKJ FAD 15.4605
941 1YKJ PHB 15.4605
942 1CDO NAD 15.4605
943 1WMA AB3 15.5797
944 1WMA NDP 15.5797
945 1EZ4 NAD 15.7895
946 4U7W NDP 15.7895
947 1TD2 PXL 16.0279
948 2VQZ MGT 16.2651
949 5ZEC NAP 17.1053
950 5DF1 58X 17.7632
951 5DF1 NAP 17.7632
952 3QFA FAD 18.1034
953 1XG5 NAP 18.2796
954 2BGM NAJ 18.705
955 1SB8 UD2 19.0789
956 1SB8 NAD 19.0789
957 4KWI 1TJ 20.9125
958 4KWI NAP 20.9125
959 3DDN HPV 25.9868
960 2DC1 NAD 30.5085
Pocket No.: 2; Query (leader) PDB : 5X9D; Ligand: 80F; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5x9d.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback