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Receptor
PDB id Resolution Class Description Source Keywords
5X8G 1.9 Å EC: 6.2.1.26 BINARY COMPLEX STRUCTURE OF A DOUBLE MUTANT I454RA456K OF O- SUCCINYLBENZOATE COA SYNTHETASE (MENE) FROM BACILLUS SUBTILW ITH ITS PRODUCT ANALOGUE OSB-NCOA AT 1.90 ANGSTROM BACILLUS SUBTILIS SUBSP. SUBTILIS STR.ORGANISM_TAXID: 224308 ADENYLATE-FORMING ENZYME ACYL-COA SYNTHETASE THIOESTER CONFORMATION COA PANTETHEINE TUNNEL ADP BINDING SUBSITEALTERNATION LARGE CONFORMATIONAL CHANGE INTER-DOMAIN LINKLIGASE
Ref.: CRYSTAL STRUCTURE OF THE THIOESTERIFICATION CONFORM BACILLUS SUBTILIS O-SUCCINYLBENZOYL-COA SYNTHETASE DISTINCT SUBSTRATE-BINDING MODE J. BIOL. CHEM. V. 292 12296 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
S0N C:508;
B:501;
D:501;
A:501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
954.663 C32 H45 N8 O20 P3 CC(C)...
PEG D:507;
D:506;
A:510;
A:508;
A:509;
C:506;
C:507;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
106.12 C4 H10 O3 C(COC...
CA C:502;
C:503;
C:501;
A:505;
C:504;
B:505;
D:504;
A:506;
Invalid;
Part of Protein;
Part of Protein;
Part of Protein;
Invalid;
Invalid;
Invalid;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
MG A:502;
B:503;
A:504;
D:502;
B:504;
D:503;
B:502;
C:509;
A:503;
Part of Protein;
Part of Protein;
Invalid;
Part of Protein;
Invalid;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
NA A:507;
D:505;
C:505;
B:507;
B:506;
Invalid;
Part of Protein;
Invalid;
Invalid;
Part of Protein;
none;
none;
none;
none;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5X8G 1.9 Å EC: 6.2.1.26 BINARY COMPLEX STRUCTURE OF A DOUBLE MUTANT I454RA456K OF O- SUCCINYLBENZOATE COA SYNTHETASE (MENE) FROM BACILLUS SUBTILW ITH ITS PRODUCT ANALOGUE OSB-NCOA AT 1.90 ANGSTROM BACILLUS SUBTILIS SUBSP. SUBTILIS STR.ORGANISM_TAXID: 224308 ADENYLATE-FORMING ENZYME ACYL-COA SYNTHETASE THIOESTER CONFORMATION COA PANTETHEINE TUNNEL ADP BINDING SUBSITEALTERNATION LARGE CONFORMATIONAL CHANGE INTER-DOMAIN LINKLIGASE
Ref.: CRYSTAL STRUCTURE OF THE THIOESTERIFICATION CONFORM BACILLUS SUBTILIS O-SUCCINYLBENZOYL-COA SYNTHETASE DISTINCT SUBSTRATE-BINDING MODE J. BIOL. CHEM. V. 292 12296 2017
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5X8F - AMP C10 H14 N5 O7 P c1nc(c2c(n....
2 5X8G - S0N C32 H45 N8 O20 P3 CC(C)(CO[P....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5X8F - AMP C10 H14 N5 O7 P c1nc(c2c(n....
2 5X8G - S0N C32 H45 N8 O20 P3 CC(C)(CO[P....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5X8F - AMP C10 H14 N5 O7 P c1nc(c2c(n....
2 5X8G - S0N C32 H45 N8 O20 P3 CC(C)(CO[P....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: S0N; Similar ligands found: 129
No: Ligand ECFP6 Tc MDL keys Tc
1 S0N 1 1
2 SCO 0.816794 0.977012
3 0T1 0.78626 0.954545
4 DCA 0.784615 0.932584
5 COA 0.772727 0.954545
6 COW 0.771429 0.966292
7 CAO 0.768657 0.923077
8 CMX 0.762963 0.977012
9 ETB 0.757576 0.9
10 FCX 0.757353 0.944444
11 AMX 0.755556 0.965517
12 30N 0.755556 0.875
13 COS 0.755556 0.933333
14 2NE 0.75 0.955556
15 ACO 0.744526 0.923077
16 FAM 0.744526 0.933333
17 SOP 0.741007 0.933333
18 OXK 0.741007 0.955056
19 COK 0.741007 0.933333
20 MCD 0.741007 0.955056
21 SCA 0.739437 0.955056
22 HAX 0.73913 0.933333
23 BCO 0.737589 0.933333
24 CO6 0.735714 0.933333
25 CMC 0.735714 0.955056
26 BYC 0.734266 0.955056
27 2KQ 0.734266 0.934066
28 FYN 0.733813 0.954545
29 3KK 0.733813 0.933333
30 YE1 0.732394 0.965909
31 SCD 0.730496 0.977012
32 CA6 0.728571 0.848485
33 1HE 0.725352 0.913043
34 MLC 0.725352 0.955056
35 1VU 0.723404 0.923077
36 NMX 0.723404 0.884211
37 CA8 0.722222 0.867347
38 3CP 0.722222 0.955056
39 HGG 0.722222 0.955056
40 MCA 0.72028 0.944444
41 CAA 0.72028 0.94382
42 CAJ 0.71831 0.955056
43 2MC 0.71831 0.893617
44 FAQ 0.717241 0.955056
45 2CP 0.715278 0.944444
46 IVC 0.713287 0.94382
47 A1S 0.713287 0.933333
48 3HC 0.713287 0.94382
49 GRA 0.712329 0.955056
50 HXC 0.712329 0.913043
51 COF 0.710345 0.913043
52 0FQ 0.709459 0.955056
53 COO 0.708333 0.933333
54 BCA 0.705479 0.944444
55 MC4 0.703448 0.884211
56 CO8 0.702703 0.913043
57 HFQ 0.701987 0.955556
58 1GZ 0.69863 0.923077
59 IRC 0.69863 0.94382
60 MYA 0.697987 0.913043
61 5F9 0.697987 0.913043
62 ST9 0.697987 0.913043
63 MFK 0.697987 0.913043
64 DCC 0.697987 0.913043
65 UCC 0.697987 0.913043
66 TGC 0.695946 0.944444
67 HDC 0.695364 0.913043
68 4CA 0.693878 0.944444
69 CIC 0.691275 0.955056
70 1CZ 0.691275 0.944444
71 CS8 0.688742 0.903226
72 4CO 0.686667 0.944444
73 1HA 0.685897 0.955556
74 UOQ 0.684211 0.913043
75 NHM 0.684211 0.913043
76 NHW 0.684211 0.913043
77 0ET 0.682119 0.913043
78 01A 0.682119 0.913979
79 1CV 0.677632 0.955056
80 WCA 0.677632 0.934066
81 4KX 0.673203 0.923913
82 MRS 0.668831 0.913043
83 MRR 0.668831 0.913043
84 YNC 0.664516 0.923077
85 DAK 0.664516 0.923913
86 8Z2 0.660256 0.903226
87 COT 0.65625 0.955056
88 CA3 0.648148 0.955056
89 F8G 0.645963 0.914894
90 NHQ 0.641509 0.94382
91 01K 0.62963 0.933333
92 COD 0.628571 0.943182
93 CCQ 0.625806 0.893617
94 93P 0.625 0.966292
95 CA5 0.619048 0.913979
96 7L1 0.619048 0.923077
97 93M 0.606936 0.966292
98 UCA 0.605882 0.934066
99 CO7 0.597403 0.933333
100 OXT 0.562842 0.914894
101 JBT 0.550265 0.915789
102 5TW 0.548387 0.894737
103 4BN 0.548387 0.894737
104 BSJ 0.543478 0.945055
105 PLM COA 0.53012 0.88172
106 COA PLM 0.53012 0.88172
107 PAP 0.51938 0.793103
108 HMG 0.518072 0.922222
109 ASP ASP ASP ILE CMC NH2 0.483516 0.912088
110 PPS 0.474074 0.71875
111 A3P 0.472868 0.781609
112 4YB 0.466216 0.755102
113 0WD 0.461538 0.791209
114 RFC 0.449438 0.934066
115 SFC 0.449438 0.934066
116 ACE SER ASP ALY THR NH2 COA 0.439394 0.912088
117 191 0.438596 0.848485
118 PTJ 0.421769 0.873563
119 A22 0.41958 0.816092
120 3AM 0.415385 0.770115
121 PUA 0.412121 0.822222
122 ATR 0.410072 0.781609
123 NA7 0.408163 0.83908
124 PAJ 0.40411 0.885057
125 A2D 0.402985 0.804598
126 A2R 0.402778 0.816092
127 3OD 0.402685 0.827586
128 AGS 0.4 0.769231
129 SAP 0.4 0.769231
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5X8G; Ligand: S0N; Similar sites found with APoc: 186
This union binding pocket(no: 1) in the query (biounit: 5x8g.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 5CLO NS8 None
2 6CS9 PIO None
3 2W41 ADP 1.4433
4 5W75 SUC 1.53061
5 1JIL 485 1.66667
6 3HQ9 OXL 1.73913
7 3TAO PGH 1.87266
8 6F5W KG1 1.89702
9 1WOG 16D 1.96721
10 1TRD PGH 2
11 5YJS SAL 2.05128
12 4ZNO SUC 2.08955
13 4XFR CIT 2.10773
14 4KBA 1QM 2.1148
15 4WKI 3PW 2.12766
16 6C92 EGV 2.12766
17 1CZA G6P 2.26804
18 3VSV XYS 2.26804
19 1MXG ACR 2.29885
20 1GVF PGH 2.44755
21 3JQ3 ADP 2.45902
22 5VLC HSO 2.46637
23 5UL4 SAM 2.47423
24 4CNG SAH 2.47423
25 1WUU GLA 2.50627
26 3T4L ZEA 2.59259
27 2JBH 5GP 2.66667
28 3Q3H UDP 2.68041
29 1LYX PGA 2.82258
30 2VAR AMP 2.8754
31 4L8F MTX 2.88462
32 5L2R MLA 2.8866
33 5DG2 GAL GLC 2.96296
34 1W55 C 2.96496
35 3NZ1 3NY 3.06513
36 1Y7P RIP 3.13901
37 2D6M LBT 3.14465
38 3BJE URA 3.15186
39 6A63 LAT 3.29897
40 1BW9 PPY 3.37079
41 1GPM AMP 3.50515
42 4ZU3 4SD 3.52423
43 1PIE GLA 3.57995
44 4RD0 GDP 3.61446
45 1ONI BEZ 3.62319
46 1SW0 PGA 3.62903
47 6BVE PGA 3.67347
48 6GNO XDI 3.7037
49 4RF7 ARG 3.71134
50 5EJL C2E 3.71134
51 6GNF GLC 3.71134
52 3ICS ADP 3.71134
53 3LGS ADE 3.74532
54 3OPT AKG 3.75335
55 1RZU ADP 3.91753
56 1QDS PGA 3.98406
57 2RDE C2E 3.98406
58 3CBC DBS 4.0404
59 4NYT PC 4.14747
60 5ETJ IM5 4.32099
61 5F7J ADE 4.375
62 1RYD GLC 4.39277
63 3JQQ A2P 4.43038
64 1OSS BEN 4.4843
65 2PNC CLU 4.53608
66 1UYY BGC BGC 4.58015
67 6FA4 D1W 4.62428
68 2V57 PRL 4.73684
69 3WV6 GAL BGC 4.74227
70 4WOE ADP 4.74227
71 2BTM PGA 4.7619
72 1UKG MMA 4.7619
73 1Q8V MAN MAN MAN 4.7619
74 2AUY NAG MAN MMA 4.7619
75 1Q8P MAN MMA 4.7619
76 5EYW PGA 4.81928
77 2J5B TYE 4.88506
78 1QKQ MAN 4.92958
79 3QPB URA 4.96454
80 3VV1 GAL FUC 5
81 3OQJ 3CX 5.05837
82 5M6N 7H9 5.08475
83 5VM6 9EG 5.10949
84 5YRV 5AD 5.10949
85 5EO8 TFU 5.14469
86 4BTV RB3 5.23256
87 4URS C2E 5.31915
88 4NAE 1GP 5.33333
89 5KJW 53C 5.36082
90 3CM2 X23 5.38462
91 2G30 ALA ALA PHE 5.42636
92 3KVY URA 5.50162
93 2VDF OCT 5.5336
94 5TSH ADP 5.56701
95 1XXR MAN 5.59006
96 4K55 H6P 5.64516
97 1GT4 UNA 5.66038
98 4M3P HCS 5.66502
99 1I1E DM2 5.7732
100 6EK3 OUL 5.88235
101 1ICV NIO 5.99078
102 2EB5 OXL 5.99251
103 1F9V ADP 6.05187
104 5L83 ASP TRP GLU ILE VAL 6.25
105 4AF5 CIT 6.31579
106 5TCI MLI 6.34146
107 5IFK HPA 6.41026
108 5G48 1FL 6.41711
109 4BG4 ARG 6.46067
110 5TDF 7A3 6.48148
111 1WZ1 DNS 6.50407
112 2I6U CP 6.51466
113 6E1Q CFA 6.59794
114 3SAO DBH 6.875
115 3UW5 MAA CHG PRO 0DQ 6.89655
116 5DYO FLU 7.07547
117 4DD8 BAT 7.21154
118 3NV3 GAL NAG MAN 7.24638
119 5TQZ GLC 7.33333
120 4GDX GLU 7.69231
121 2YKL NLD 7.87037
122 4YMZ 13P 7.96813
123 1WAP TRP 8
124 3G1Z AMP 8.28221
125 1I7Q PYR 8.29016
126 2P4S DIH 8.31099
127 3F9W SAH 8.43373
128 1U29 I3P 8.52713
129 1RJW ETF 8.55457
130 5ABU GTG 8.57143
131 5EY9 5SV 8.65979
132 5HM3 649 8.65979
133 1VMK GUN 8.66426
134 3WUD GLC GAL 8.82353
135 3OYW TDG 8.95522
136 2YPI PGA 9.31174
137 5WHU SIA GAL GLC 9.39597
138 1A0J BEN 9.41704
139 4BI7 PGA 9.72763
140 5N53 8NB 9.74359
141 3L4N GSH 10.2362
142 1H5S TMP 10.2389
143 1UTJ ABN 10.3306
144 2XG5 EC2 10.4046
145 2XG5 EC5 10.4046
146 5YRF GLC GLC 11.9718
147 5YRI GLC GLC 11.9718
148 5YRJ BGC GLC 11.9718
149 5YRG BGC GLC 11.9718
150 2HYQ MAN MAN 12.2951
151 2NUO BGC 12.2951
152 2GUC MAN 12.2951
153 1SLT NDG GAL 12.6866
154 3KO0 TFP 12.8713
155 1W8S FBP 12.9278
156 3WD6 GSH 13.2812
157 4RLT FSE 13.2911
158 2YMZ LAT 13.8462
159 5F6U 5VK 14.6497
160 5H2U 1N1 14.9813
161 4C2W ANP 15.3846
162 2JKY 5GP 16.9014
163 2Y4O DLL 23.4763
164 3IWD M2T 25.8065
165 5MST FUM 26.8041
166 5MST AMP 26.8041
167 5MSD BEZ 34.6392
168 2D1S SLU 35.8763
169 5OE4 3UK 36.6093
170 4R0M FA5 37.732
171 4D57 ARG AMP 43.0928
172 4OXI GAP 43.5052
173 5N9X THR 43.9175
174 5N9X 8QN 43.9175
175 3NYQ MCA 44.3564
176 3NYQ AMP 44.3564
177 2V7B BEZ 45.1546
178 3O84 HTJ 45.9794
179 5WM2 SAL 45.9794
180 3C5E ATP 46.5979
181 4RLQ 3SK 47.0103
182 3IES M24 47.2165
183 1PG4 PRX 48.0412
184 1PG4 COA 48.0412
185 1RY2 AMP 48.2474
186 3CW9 01A 49.2784
Pocket No.: 2; Query (leader) PDB : 5X8G; Ligand: S0N; Similar sites found with APoc: 121
This union binding pocket(no: 2) in the query (biounit: 5x8g.bio1) has 49 residues
No: Leader PDB Ligand Sequence Similarity
1 6FX2 FUC C4W NAG BMA MAN NAG GAL None
2 4ZH7 FUC GAL NAG GAL FUC 1.23711
3 3CV2 COA 1.4433
4 1YBQ BDH 1.53846
5 3A16 PXO 1.60858
6 2A1X AKG 1.62338
7 5KOD AMP 1.64948
8 4EPM AMP 1.64948
9 2GKS ADP 1.64948
10 2OG2 MLI 1.67131
11 1YQT ADP 1.85567
12 4NOS ITU 1.87354
13 3H4L ANP 1.90736
14 1ZGS XMM 2.01342
15 6F9G PUT 2.18069
16 4B2G V1N 2.26804
17 4RDL FUC GAL NDG FUC 2.27273
18 1KNM LAT 2.30769
19 3UDG TMP 2.32558
20 4YVN EBS 2.47423
21 2QLU ADE 2.54777
22 2WBV SIA 2.6455
23 4LJ9 ACP 2.65487
24 1PQ7 ARG 2.67857
25 5ZI9 FLC 2.69231
26 2VL1 GLY GLY 2.74262
27 2D24 XYS XYS 2.75229
28 2CJ9 SSA 2.8866
29 3WR7 COA 2.94118
30 4K37 SAM 2.97297
31 5LE1 6UW 3.00752
32 4B16 NAG 3.00752
33 4KS7 X4Z 3.08219
34 4IRP UDP 3.18725
35 2H3H BGC 3.19489
36 3EZ2 ADP 3.26633
37 3P2H NOO 3.48259
38 2GEK GDP 3.50515
39 1C1X HFA 3.50515
40 3TW1 AHN 3.79747
41 6ACS CIT 3.87597
42 3I9U DTU 3.91753
43 3RL3 5GP 4.05405
44 3A3B RBF 4.21053
45 2Z6J TUI 4.21687
46 5LX9 OLB 4.22535
47 2OUA AES 4.25532
48 2F6U CIT 4.2735
49 5MTE BB2 4.37956
50 2VWT PYR 4.49438
51 1O9W NAG 4.51977
52 3A2Q ACA ACA 4.53608
53 3QXV MTX 4.7619
54 3IVV ASP GLU VAL THR SER THR THR SER SER SER 4.82759
55 3G5K BB2 4.91803
56 2Z3U CRR 4.94118
57 3QPB R1P 4.96454
58 4P4T GDP 5
59 4UWM FMN 5.02645
60 2YIP YIO 5.07246
61 4RYV ZEA 5.16129
62 5FPE 3TR 5.16796
63 2NGR AF3 5.2356
64 5A7C 5D4 5.30973
65 3QH2 3NM 5.42986
66 5LUB 3Y7 5.72519
67 1WPY BTN 5.95745
68 4SGA ACE PRO ALA PRO PHE 6.07735
69 1OJZ NAD 6.13208
70 5OCG 9R5 6.34921
71 2NU8 COA 6.39175
72 4BG4 ADP 6.46067
73 3NC9 TR3 6.70927
74 1VBO MAN 6.71141
75 3ZXE PGZ 6.76692
76 4ZFL 4NK 6.83761
77 3DZD ADP 7.06522
78 1F52 ADP 7.2165
79 3H0L ADP 7.44681
80 5N58 93W 7.5188
81 1DBT U5P 7.53138
82 3NK7 SAM 7.58123
83 1V59 NAD 7.74059
84 4DR9 BB2 8.33333
85 1V9A SAH 8.3682
86 1OKE BOG 8.62944
87 3HYK A3P 9.01639
88 3BQF SSM 9.27835
89 5AHW CMP 9.52381
90 5BN3 ADP 9.69072
91 6GMR F4K 10.1695
92 4ITH RCM 10.2041
93 1BC5 ACE ASN TRP GLU THR PHE 10.4089
94 4OKE AMP 10.7143
95 3NY4 SMX 10.9434
96 5XQW 8EU 12.7962
97 5FUI APY 12.8788
98 1W6P NDG GAL 14.9254
99 3A1S GDP 15.5039
100 1PVC ILE SER GLU VAL 17.6471
101 1G0V NAG 19.3548
102 2R0H CTO 22.561
103 4DG8 AMP 27.6289
104 3KXW 1ZZ 34.433
105 5MSD AMP 34.6392
106 5D6J ATP 34.6392
107 3DHV DAL AMP 41.2371
108 3E7W AMP 42.4742
109 4FUT ATP 42.4742
110 4GR5 APC 42.6804
111 5N81 8Q2 43.3255
112 4GXQ ATP 43.7113
113 5N9X ATP 43.9175
114 1AMU AMP 44.3299
115 5YV5 ADP 44.4444
116 1MDB AMP DBH 45.1546
117 5WM2 AMP 45.9794
118 1V25 ANP 47.0103
119 5IE3 OXD 48.4536
120 5IE3 AMP 48.4536
121 3CW9 AMP 49.2784
Pocket No.: 3; Query (leader) PDB : 5X8G; Ligand: S0N; Similar sites found with APoc: 61
This union binding pocket(no: 3) in the query (biounit: 5x8g.bio2) has 47 residues
No: Leader PDB Ligand Sequence Similarity
1 2RDG NDG FUC SIA GAL 1.02041
2 2OO0 PLP 1.27389
3 1TV5 A26 1.58014
4 2I4O ATP 1.96507
5 5H4S RAM 2.11268
6 1KDK DHT 2.25989
7 3IWK NAD 2.26804
8 6G5J EM8 2.42424
9 2VAR ANP 2.8754
10 6AYU F6P 2.88184
11 5X30 4LM 3.01508
12 2OJW ADP 3.125
13 1HPG BOC ALA ALA PRO GLU 3.20856
14 5TG5 JW8 3.26531
15 4R81 FMN 3.39806
16 3AI3 SOL 3.71134
17 3THR C2F 3.75427
18 4RDH AMP 3.81944
19 1TO9 HMH 3.84615
20 4G0P U5P 4.08163
21 6CC0 EWM 4.21941
22 3RGA LSB 4.24028
23 1JGS SAL 4.34783
24 1VM6 NAD 4.38596
25 3CT5 NAG NAG NAG 4.40252
26 1PJS NAD 4.814
27 4URF 1PS 4.83871
28 4DO1 ANN 4.87805
29 1NXJ GLV 5.46448
30 5DVI BGC 5.96659
31 2WJH GDP 6.0241
32 5T46 MGP 6.06061
33 1JPA ANP 6.41026
34 1WS1 BB2 6.41026
35 1U8Z GDP 6.54762
36 4DS0 A2G GAL NAG FUC 6.74847
37 5GQI ATP 6.88259
38 1MRH FMC 7.01031
39 5E95 GDP 7.2165
40 4FK7 P34 8.29694
41 1S17 GNR 8.88889
42 5TVA COA 9.16667
43 1H5R THM 10.2389
44 4CNK MEU 10.5155
45 2AK3 AMP 10.6195
46 1DZK PRZ 11.465
47 5YRM BGC GLC 11.9718
48 5YRL GLC GLC 11.9718
49 2HYR BGC GLC 12.2951
50 2GUD BMA 12.2951
51 2NU5 NAG 12.2951
52 2GUD MAN 12.2951
53 4OWK NGA 12.3188
54 1NFS DED 12.5683
55 4UEC MGT 12.8205
56 5KWY C3S 14.17
57 3N8K D1X 15.6977
58 5JBX MLI 15.7088
59 5HZX 2GE 18.75
60 6E2B PT7 19.7368
61 3KMW ATP 32.5581
Pocket No.: 4; Query (leader) PDB : 5X8G; Ligand: S0N; Similar sites found with APoc: 23
This union binding pocket(no: 4) in the query (biounit: 5x8g.bio2) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 4F4S EFO None
2 1IS3 LAT 1.48148
3 2C5S AMP 1.69492
4 6CFC BLG 2.26804
5 3KU0 ADE 2.39044
6 2XYA 7L4 3.2967
7 1DKU AP2 3.47003
8 4AVB CMP 3.6036
9 3ZF8 GDP 3.60656
10 1K3A ACP 3.67893
11 3WUC GLC GAL 4.37956
12 5GLT BGC GAL NAG GAL 4.57746
13 5JJU AMP 4.70588
14 1C3M MAN MAN 4.7619
15 2PHX MAN MAN MAN MAN 4.7619
16 4D52 GXL 5.07937
17 3PQC GDP 6.66667
18 1JTQ LY3 7.57576
19 2FLI DX5 9.09091
20 3VY6 BGC BGC 11.3475
21 1QAW TRP 12.1622
22 2FN1 PYR 12.1649
23 2BS3 CIT 15.0628
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