-->
Receptor
PDB id Resolution Class Description Source Keywords
5W6A 1.74 Å NON-ENZYME: IMMUNE HLA-C*06:02 PRESENTING ARTELYRSL HOMO SAPIENS HLA ANTIGEN PRESENTATION HUMAN LEUKOCYTE ANTIGEN IMMUNE S
Ref.: THE MOLECULAR BASIS FOR PEPTIDE REPERTOIRE SELECTIO HUMAN LEUCOCYTE ANTIGEN (HLA) C*06:02 MOLECULE. J. BIOL. CHEM. V. 292 17203 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ALA ARG THR GLU LEU TYR ARG SER LEU E:1;
F:1;
Valid;
Valid;
none;
none;
submit data
1109.27 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5U98 2 Å NON-ENZYME: IMMUNE THE CRYSTAL STRUCTURE OF A SELF-PEPTIDE COMPLEXED TO ABACAVI B*57:01 HOMO SAPIENS MHC ANTIGEN PRESENTING CELL T-CELL RECEPTOR HUMAN LEUKOCYANTIGEN DRUG HYPERSENSITIVITY ABACAVIR HYPERSENSITIVITY REPERTOIRE-ALTERING SMALL MOLECULE IMMUNE RESPONSE IMMUNOLIKE BETA-SANDWICH IMMUNE SYSTEM
Ref.: STRUCTURAL ELEMENTS RECOGNIZED BY ABACAVIR-INDUCED INT J MOL SCI V. 18 2017
Members (109)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 208 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
70% Homology Family (360)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 62 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
110 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
111 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
112 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
113 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
114 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
115 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
116 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
117 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
118 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
119 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
120 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
121 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
122 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
123 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
124 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
125 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
126 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
127 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
128 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
129 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
130 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
132 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
133 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
134 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
135 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
136 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
137 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
138 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
139 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
140 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
141 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
142 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
143 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
144 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
145 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
146 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
147 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
148 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
149 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
150 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
151 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
152 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
153 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
154 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
155 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
156 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
157 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
158 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
159 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
160 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
161 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
162 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
163 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
164 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
165 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
166 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
167 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
168 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
169 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
170 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
171 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
172 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
173 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
174 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
175 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
176 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
177 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
178 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
179 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
180 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
181 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
182 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
183 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
184 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
185 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
186 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
187 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
188 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
189 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
190 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
191 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
192 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
193 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
194 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
195 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
196 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
197 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
198 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
199 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
200 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
201 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
202 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
203 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
204 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
205 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
206 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
207 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
208 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
209 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
210 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
211 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
212 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
213 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
214 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
215 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
216 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
217 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
218 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
219 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
220 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
221 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
222 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
223 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
224 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
225 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
226 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
227 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
228 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
229 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
230 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
231 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
232 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
233 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
234 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
235 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
236 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
237 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
238 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
239 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
240 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
241 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
242 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
243 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
244 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
245 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
246 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
247 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
248 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
249 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
251 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
252 1HSB - ALA VAL ALA n/a n/a
253 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
254 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
255 5GRG - SER SER CYS SER SER CYS n/a n/a
256 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
257 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
258 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
259 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
260 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
261 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
262 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
263 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
264 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
265 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
266 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
267 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
268 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
269 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
270 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
271 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
272 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
274 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
275 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
276 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
277 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
278 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
279 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
281 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
282 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
283 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
284 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
285 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
286 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
288 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
289 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
291 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
292 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
293 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
294 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
295 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
296 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
297 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
298 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
299 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
300 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
301 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
303 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
304 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
305 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
306 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
307 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
308 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
309 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
310 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
311 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
312 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
313 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
314 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
315 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
316 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
317 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
318 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
319 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
320 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
321 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
322 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
323 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
324 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
325 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
326 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
327 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
328 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
329 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
330 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
331 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
332 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
333 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
334 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
335 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
336 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
337 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
338 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
339 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
340 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
341 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
342 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
343 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
344 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
345 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
346 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
347 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
348 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
349 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
350 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
351 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
352 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
353 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
354 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
355 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
356 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
357 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
358 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
359 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
360 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
50% Homology Family (366)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 42 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
110 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
111 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
112 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
113 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
114 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
115 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
116 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
117 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
118 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
119 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
120 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
121 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
122 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
123 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
124 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
125 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
126 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
127 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
128 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
129 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
130 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
132 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
133 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
134 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
135 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
136 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
137 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
138 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
139 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
140 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
141 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
142 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
143 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
144 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
145 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
146 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
147 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
148 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
149 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
150 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
151 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
152 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
153 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
154 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
155 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
156 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
157 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
158 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
159 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
160 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
161 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
162 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
163 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
164 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
165 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
166 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
167 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
168 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
169 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
170 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
171 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
172 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
173 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
174 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
175 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
176 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
177 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
178 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
179 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
180 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
181 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
182 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
183 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
184 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
185 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
186 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
187 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
188 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
189 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
190 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
191 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
192 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
193 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
194 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
195 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
196 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
197 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
198 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
199 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
200 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
201 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
202 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
203 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
204 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
205 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
206 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
207 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
208 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
209 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
210 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
211 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
212 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
213 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
214 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
215 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
216 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
217 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
218 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
219 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
220 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
221 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
222 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
223 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
224 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
225 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
226 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
227 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
228 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
229 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
230 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
231 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
232 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
233 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
234 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
235 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
236 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
237 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
238 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
239 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
240 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
241 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
242 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
243 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
244 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
245 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
246 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
247 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
248 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
249 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
251 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
252 1HSB - ALA VAL ALA n/a n/a
253 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
254 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
255 5GRG - SER SER CYS SER SER CYS n/a n/a
256 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
257 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
258 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
259 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
260 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
261 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
262 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
263 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
264 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
265 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
266 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
267 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
268 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
269 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
270 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
271 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
272 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
274 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
275 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
276 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
277 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
278 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
279 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
281 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
282 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
283 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
284 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
285 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
286 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
288 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
289 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
291 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
292 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
293 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
294 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
295 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
296 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
297 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
298 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
299 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
300 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
301 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
303 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
304 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
305 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
306 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
307 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
308 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
309 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
310 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
311 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
312 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
313 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
314 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
315 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
316 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
317 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
318 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
319 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
320 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
321 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
322 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
323 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
324 4CVZ - TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU n/a n/a
325 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
326 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
327 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
328 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
329 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
330 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
331 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
332 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
333 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
334 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
335 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
336 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
337 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
338 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
339 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
340 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
341 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
342 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
343 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
344 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
345 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
346 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
347 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
348 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
349 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
350 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
351 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
352 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
353 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
354 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
355 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
356 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
357 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
358 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
359 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
360 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
361 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
362 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
363 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
364 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
365 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
366 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ALA ARG THR GLU LEU TYR ARG SER LEU; Similar ligands found: 245
No: Ligand ECFP6 Tc MDL keys Tc
1 ALA ARG THR GLU LEU TYR ARG SER LEU 1 1
2 ARG ARG ILE TYR ASP LEU ILE GLU LEU 0.664062 0.933333
3 ALA THR VAL ARG THR TYR SER CYS 0.658333 0.933333
4 SER SER ARG LYS GLU TYR TYR ALA 0.641026 0.83871
5 SER GLU LEU GLU ILE LYS ARG TYR 0.627907 0.95082
6 TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 0.609023 0.903226
7 SER ASP TYR GLN ARG LEU 0.605042 0.915254
8 THR ARG ARG GLU THR GLN LEU 0.6 0.881356
9 SER LEU ARG PHE LEU TYR GLU GLY 0.596899 0.919355
10 LEU GLU LYS ALA ARG GLY SER THR TYR 0.58042 0.967213
11 LEU TYR LEU VAL CYS GLY GLU ARG VAL 0.57971 0.885246
12 CYS THR GLU LEU LYS LEU SER ASP TYR 0.575758 0.852459
13 SER SER ILE GLU PHE ALA ARG LEU 0.574627 0.9
14 ACE ILE TYR GLU SER LEU 0.57265 0.8
15 GLY GLY ARG LYS LYS TYR LYS LEU 0.568 0.885246
16 GLY GLY LYS LYS LYS TYR ARG LEU 0.568 0.885246
17 GLY GLY LYS LYS ARG TYR LYS LEU 0.568 0.885246
18 ARG LEU GLN ARG ARG ARG GLU THR GLN VAL 0.565574 0.881356
19 SER GLU ILE GLU PHE ALA ARG LEU 0.56391 0.883333
20 SER SER LEU GLU ASN PHE ARG ALA TYR VAL 0.561644 0.935484
21 ALA ASN SER ARG TRP GLN ASP THR ARG LEU 0.561644 0.850746
22 ACE ALA ARG THR GLU VAL TYR NH2 0.559055 0.932203
23 GLU LEU LYS TPO GLU ARG TYR 0.557971 0.850746
24 ARG ARG ARG GLU THR GLN VAL 0.556522 0.864407
25 ALA ARG THR MLY GLN THR ALA ARG TYR 0.556391 0.865672
26 ALA ALA SER LEU TYR GLU LYS LYS ALA ALA 0.554688 0.866667
27 LEU TYR LEU VAL CYS GLY GLU ARG GLY 0.553957 0.885246
28 GLU LEU ARG ARG LYS MET MET TYR MET 0.548872 0.859375
29 GLU LEU LYS ARG LYS MET ILE TYR MET 0.546099 0.830769
30 GLY ALA ALA ARG ALA GLU VAL TYR LEU ARG 0.546099 0.916667
31 LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE 0.544828 0.857143
32 ACE GLU ALA GLN THR ARG LEU 0.544715 0.833333
33 ASN ALA LEU LEU ARG TYR LEU LEU ASP 0.542636 0.933333
34 GLU ALA GLN THR ARG LEU 0.540323 0.847458
35 ALA GLN ASP ILE TYR ARG ALA SER TYR 0.538462 0.919355
36 GLU LEU ARG SER ARG TYR TRP ALA ILE 0.532895 0.867647
37 PHE ARG TYR LEU GLY 0.531746 0.854839
38 ARG GLY TYR LEU TYR GLN GLY LEU 0.530303 0.854839
39 GLU GLU TYR LEU GLN ALA PHE THR TYR 0.525547 0.770492
40 PHE ASN GLU LEU SER HIS LEU 0.525 0.723077
41 ALA GLN PHE SER ALA SER ALA SER ARG 0.52381 0.881356
42 GLY ASN PHE LEU GLN SER ARG 0.518797 0.885246
43 ARG HIS ARG MLY VAL LEU ARG ASP TYR 0.516779 0.756757
44 ALA LEU TYR ASN THR ALA ALA ALA LEU 0.516129 0.75
45 SER LEU TYR LEU THR VAL ALA THR LEU 0.515873 0.79661
46 PHE LEU ARG GLY ARG ALA TYR VAL LEU 0.513889 0.870968
47 GLU LEU ASN ARG LYS MET ILE TYR MET 0.513333 0.848485
48 SER ARG TYR TRP ALA ILE ARG THR ARG 0.513158 0.838235
49 VAL ARG SER ARG ARG CYS LEU ARG LEU 0.512605 0.85
50 CYS THR GLU LEU LYS LEU ASN ASP TYR 0.510949 0.822581
51 GLU THR VAL ARG PHE GLN SER ASP 0.510791 0.898305
52 GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE 0.507042 0.83871
53 THR GLU ASN LEU TYR PHE GLN SER GLY THR 0.507042 0.825397
54 GLY VAL TYR ASP GLY ARG GLU HIS THR VAL 0.506579 0.850746
55 VAL ARG SER ARG ARG ABA LEU ARG LEU 0.504132 0.85
56 SER GLN TYR TYR TYR ASN SER LEU 0.5 0.806452
57 GLY ILE LEU GLU PHE VAL PHE THR LEU 0.496241 0.741935
58 PHE TYR ARG ALA LEU MET 0.492754 0.8
59 ALA ARG THR M3L GLN THR ALA ARG 0.492188 0.753623
60 ASP ALA ASP GLU TYR LEU 0.491935 0.762712
61 ALA ARG THR MLY GLN 0.491803 0.761194
62 ALA PHE ARG ILE PRO LEU THR ARG 0.489933 0.75
63 ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE 0.48951 0.883333
64 ARG GLY TYR VAL TYR GLN GLY LEU 0.489209 0.854839
65 ALA THR ARG ASN PHE SER GLY 0.488722 0.852459
66 TYR GLN SER LYS LEU 0.487805 0.85
67 PHE LEU ARG GLY ARG ALA TYR GLY LEU 0.485714 0.870968
68 THR LYS ASN TYR LYS GLN THR SER VAL 0.485507 0.852459
69 SER LEU TYR ASN THR VAL ALA THR LEU 0.485075 0.8
70 VAL LYS VAL VAL ALA LYS LYS TYR ARG ASN 0.484848 0.901639
71 SER SER THR ARG GLY ILE SER GLN LEU TRP 0.484076 0.823529
72 SER SER LEU GLU ASN PHE ALA ALA TYR VAL 0.482517 0.806452
73 GLU GLU PHE GLY ARG ALA PHE SER PHE 0.482269 0.806452
74 SER LEU TYR ASN VAL VAL ALA THR LEU 0.481481 0.8
75 GLU VAL TYR GLU SER 0.479339 0.779661
76 SAC ARG GLY THR GLN THR GLU 0.476923 0.819672
77 ASP GLU LEU GLU ILE LYS ALA TYR 0.47482 0.803279
78 SER ARG ILE ARG ILE ARG GLY TYR VAL ARG 0.47482 0.967213
79 ARG THR PHE SER PRO THR TYR GLY LEU 0.474359 0.794521
80 THR ASN GLU TYR LYS VAL 0.472441 0.786885
81 ALA THR ALA ALA ALA THR GLU ALA TYR 0.471545 0.762712
82 GLY ALA GLU THR PHE TYR VAL ASP GLY ALA 0.471429 0.777778
83 ALA ASN SER ARG TRP GLN THR SER ILE ILE 0.470968 0.808824
84 SER LEU TYR ASN THR ILE ALA THR LEU 0.470588 0.803279
85 ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR 0.470199 0.850746
86 GLY GLY LYS LYS LYS TYR GLN LEU 0.469231 0.786885
87 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.468966 0.756757
88 ALA ARG THR M3L GLN THR ALA 2MR LYS 0.468254 0.73913
89 ALA ARG THR M3L GLN THR ALA 0.468254 0.73913
90 ALA ALA LEU THR ARG ALA 0.467213 0.813559
91 ALA ARG LYS LEU ASP 0.466102 0.783333
92 LEU PRO SER PHE GLU THR ALA LEU 0.465753 0.690141
93 ILE GLN GLN SER ILE GLU ARG ILE 0.465116 0.833333
94 VAL MET ALA PRO ARG THR LEU PHE LEU 0.464968 0.697368
95 ARG ARG ARG TRP ARG ARG LEU THR VAL 0.464789 0.833333
96 GLY GLY LYS LYS LYS TYR LYS LEU 0.464 0.786885
97 LEU ASP GLU GLU THR GLY GLU PHE LEU 0.463235 0.8
98 ARG HIS ARG MLZ VAL LEU ARG ASP ASN TYR 0.4625 0.802817
99 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.462025 0.760563
100 ALA ARG THR MLY GLN THR ALA ARG LYS TYR 0.460938 0.761194
101 ALA ARG THR MLY GLN THR ALA 0.460938 0.761194
102 ALA GLU THR PHE 0.46087 0.694915
103 THR LYS ASN TYR LYS GLN PHE SER VAL 0.459854 0.809524
104 ALA MET ALA PRO ARG THR LEU LEU LEU 0.458333 0.671053
105 VAL PRO LEU ARG PRO MET THR TYR 0.458065 0.76
106 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.457516 0.75
107 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.45679 0.76
108 ALA ARG THR ALY GLN THR ALA 0.456693 0.790323
109 ALA PRO ALA LEU ARG VAL VAL LYS 0.455285 0.75
110 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.455128 0.780822
111 PHE LEU SER TYR LYS 0.453846 0.806452
112 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.453416 0.802817
113 ALA ARG THR M3L GLN THR ALA ARG LYS 0.453125 0.73913
114 ALA ARG THR M3L GLN THR ALA ARG LYS SER 0.453125 0.73913
115 ARG PRO MET THR TYR LYS GLY ALA LEU 0.452381 0.75
116 ARG VAL LEU PHE GLU ALA MET 0.451389 0.765625
117 GLU GLU TYR LEU LYS ALA TRP THR PHE 0.450617 0.75
118 GLU ASN PRO THR TYR LYS PHE PHE GLU GLN 0.450382 0.774194
119 THR TYR LYS PHE PHE GLU GLN 0.450382 0.774194
120 ALA ARG THR M3L GLN THR ALA ALA LYS ALA 0.449275 0.753623
121 LYS ALA ARG VAL LEU ALA GLU ALA MET 0.449275 0.714286
122 GLU GLN TYR LYS PHE TYR SER VAL 0.449275 0.822581
123 LYS ALA ARG VAL LEU ALA GLU ALA MET SER 0.449275 0.714286
124 ARG GLU ARG SER PRO THR ARG 0.448819 0.676056
125 VAL LEU ARG ASP ASP LEU LEU GLU ALA 0.448 0.813559
126 PTR LEU ARG VAL ALA 0.447761 0.787879
127 PHE ALA GLY LEU ARG GLN ALA VAL THR GLN 0.447761 0.833333
128 ASP ALA GLU PHE ARG HIS ASP 0.447761 0.79661
129 THR ASN GLU TYR TYR VAL 0.446281 0.709677
130 ALA ARG THR MLY GLN THR ALA ARG LYS 0.446154 0.746269
131 GLY ALA GLN THR PHE TYR VAL ASP GLY ALA 0.446043 0.790323
132 GLU LEU ASP LYS TYR ALA SER 0.445255 0.85
133 GLU ASP GLU ASP PHE GLU ILE LEU SER LEU 0.444444 0.8
134 ALA PTR ARG 0.442623 0.742424
135 LEU PRO PHE GLU ARG ALA THR VAL MET 0.442424 0.72
136 ALA ARG 9AT 0.439252 0.779661
137 ALA ARG THR 4WQ GLN THR ALA ARG LYS SER 0.439024 0.765625
138 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.4375 0.706667
139 LEU PRO PHE GLU ARG ALA THR ILE MET 0.437126 0.710526
140 ALA ARG M3L SER THR GLY GLY ALY 0.43662 0.757143
141 ACE ARG GLU PTR VAL ASN VAL 0.43662 0.794118
142 SER ILE ILE ASN PHE GLU LYS LEU 0.43662 0.774194
143 PRO LEU GLU PSA ARG LEU 0.436242 0.830769
144 LYS THR LYS LEU LEU 0.435897 0.733333
145 GLY ALA GLU VAL PHE TYR VAL ASP GLY ALA 0.435714 0.730159
146 ALA ARG THR MLZ GLN THR ALA ARG LYS TYR 0.435115 0.765625
147 ASP ILE ALA TYR TYR THR SER GLU PRO 0.434483 0.689189
148 ILE LEU GLY LYS PHE LEU HIS ARG LEU 0.434211 0.724638
149 OSL DLE THR ARG GLU LEU YNM VAL 0.433121 0.7125
150 ALA ARG THR LYS GLN THR ALA ARG LYS 0.432836 0.816667
151 MET ABA LEU ARG MET THR ALA VAL MET 0.432624 0.78125
152 ASP LEU TYR CYS TYR GLU GLN LEU ASN 0.431655 0.777778
153 ALA ARG THR MLY GLN THR ALA ARG MLY SER 0.429688 0.746269
154 ACE CSO ARG ALA THR LYS MET LEU 0.429577 0.732394
155 ALA SER ASN GLU HIS MET GLU THR MET 0.429577 0.710145
156 ARG PHE MET ASP TYR TRP GLU GLY LEU 0.428571 0.75
157 LEU LYS THR LYS LEU LEU 0.428571 0.733333
158 ALA ARG THR LYS GLN THR ALA ARG 0.428571 0.8
159 THR ASN GLU PHE TYR ALA 0.427481 0.725806
160 ILE ARG LYS ILE LEU PHE LEU ASP GLY ILE 0.425806 0.793651
161 ALA LYS PHE ARG HIS ASP 0.425532 0.716418
162 GLU ASN LEU TYR PHE GLN 0.425373 0.741935
163 GLY ASN TYR SER PHE TYR ALA LEU 0.425373 0.777778
164 ALA ILE PHE GLN SER SER MET THR LYS 0.424658 0.753846
165 ASN ARG LEU MET LEU THR GLY 0.424242 0.796875
166 ALA ARG SER HIS SEP TYR PRO ALA 0.424242 0.6875
167 SER ILE ILE GLY PHE GLU LYS LEU 0.423611 0.758065
168 MET CYS LEU ARG MET THR ALA VAL MET 0.423611 0.809524
169 ALA ARG MLY SER THR GLY GLY ALY 0.423611 0.779412
170 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.422857 0.773333
171 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.421687 0.76
172 PHQ LEU VAL ARG TYR 0.421429 0.857143
173 ARG HIS ARG MLY VAL LEU ARG ASP ASN 0.421053 0.712329
174 ALA ARG THR MLZ GLN THR ALA ARG LYS 0.42029 0.78125
175 ASP SEP TYR GLU VAL LEU ASP LEU 0.42 0.742424
176 ASP ASN ARG LEU GLY LEU VAL TYR GLN PHE 0.419847 0.704918
177 ALA ARG LYS ILE ASP ASN LEU ASP 0.41844 0.806452
178 ACE GLN LEU VAL THR SER LEU 0.418033 0.733333
179 SER GLU ASP GLU PHE TYR ASP ALA LEU SER 0.417808 0.819672
180 THR PHE GLN ALA PSA LEU ARG GLU 0.417722 0.857143
181 LYS LYS ALA THR GLN ALA SEP GLN GLU TYR 0.417323 0.712121
182 ALA SER ASN GLU ASN MET GLU THR MET 0.417323 0.703125
183 LEU ALA ILE TYR SER 0.417323 0.75
184 LYS ALA VAL TYR ASN LEU ALA THR MET 0.417219 0.784615
185 GLU ARG GLU SEP GLU PHE ASP ILE GLU ASP 0.416667 0.776119
186 TYR HIS SEP VAL VAL ARG TYR ALA 0.416667 0.743243
187 PRO ALA ILE LEU TYR ALA LEU LEU SER SER 0.416667 0.772727
188 ARG ARG LEU ILE PHE NH2 0.416667 0.766667
189 ARG PRO PRO ILE PHE ILE ARG ARG LEU 0.416667 0.694444
190 FME TYR PHE ILE ASN ILE LEU THR LEU 0.416107 0.716418
191 GLY ARG PHE GLN VAL THR 0.416058 0.816667
192 ACE VAL LYS GLU SER LEU VAL 0.416 0.733333
193 THR ASN GLU PHE TYR PHE 0.416 0.66129
194 GLY SER HIS LEU GLU VAL GLN GLY TYR TRP 0.415205 0.768116
195 MET CYS LEU ARG NLE THR ALA VAL MET 0.414966 0.796875
196 GLU ASN GLN LYS GLU TYR PHE PHE 0.414815 0.730159
197 ALA ARG THR ALA ALA THR ALA ARG LYS SER 0.414634 0.79661
198 SER TRP PHE GLN THR ASP LEU 0.414474 0.716418
199 ALA ARG MLZ SER THR GLY GLY ALY 0.413793 0.8
200 GLY GLU ARG THR ILE PRO ILE THR ARG GLU 0.413333 0.722222
201 TYR GLN GLU SER THR ASP PHE THR PHE LEU 0.412698 0.688525
202 PRO GLU GLY ASP PM3 GLU GLU VAL LEU 0.412587 0.681818
203 ALA SER ASN GLU ASN TRP GLU THR MET 0.412162 0.676056
204 ASP ALA GLU PHE ARG HIS ASP SER 0.412162 0.727273
205 ALA ASN SER ARG TRP ALY THR SER ILE ILE 0.412121 0.774648
206 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.411765 0.75
207 SER LEU PHE ASN THR VAL ALA THR LEU 0.411348 0.75
208 ILE LYS ARG SER MLZ LYS ASN SER LEU ALA 0.41129 0.75
209 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.411043 0.739726
210 ALA DA2 THR M3L GLN THR ALA ARG ALA 0.410959 0.73913
211 ARG GLY PHE ALA LEU M3L SER THR HIS GLY 0.410714 0.727273
212 PRO GLU SEP LEU GLU SER CYS PHE 0.410072 0.701493
213 GLU ILE ILE ASN PHE GLU LYS LEU 0.409722 0.725806
214 DTY ILE ARG LEU LPD 0.409722 0.708333
215 LYS ALA LEU TYR ASN PHE ALA THR MET 0.409091 0.761194
216 ASP ILE ASN TYR TYR THR SER GLU PRO 0.409091 0.68
217 GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS 0.40884 0.72
218 THR SER THR LEU GLN GLU GLN ILE GLY TRP 0.408805 0.735294
219 ALA ARG THR MLY GLN THR ALA ARG LYS SER 0.408 0.783333
220 ILE LEU ALA LYS PHE LEU HIS THR LEU 0.407895 0.720588
221 TYR PRO LYS ARG ILE ALA 0.407895 0.722222
222 GLY LEU TYR ALA SER LYS LEU ALA 0.407407 0.819672
223 ARG ILE ILE PRO ARG HIS LEU GLN LEU 0.407407 0.675676
224 GLY ALA ASP ILE PHE TYR LEU ASP GLY ALA 0.407143 0.698413
225 ALA LYS GLU LYS SER ASP 0.40678 0.716667
226 ILE LEU ALA LYS PHE LEU HIS GLU LEU 0.406667 0.661765
227 GLU ASP GLU ASP PHE GLU ILE LEU SEP LEU 0.406452 0.671642
228 SER SER TYR ARG ARG PRO VAL GLY ILE 0.40625 0.805556
229 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.40625 0.720588
230 LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.406061 0.72
231 ALA SER ASN GLU ASN ALA GLU THR MET 0.406015 0.703125
232 VAL GLN GLN GLU SER SER PHE VAL MET 0.405797 0.746032
233 ALA SER ASN GLU ASP MET GLU THR MET 0.40458 0.703125
234 LYS SER LEU LEU GLN GLN LEU LEU THR GLU 0.404412 0.783333
235 ACE GLU ASN LEU TYR PHE GLN SER GLY THR 0.404255 0.730159
236 ALA ILE LEU HIS ARG LEU LEU GLN 0.40411 0.712121
237 GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 0.403974 0.710145
238 ALA ARG THR M3L GLN THR ALA DA2 LYS 0.403846 0.73913
239 GLN THR ALA ARG M3L SER THR GLY 0.402778 0.753623
240 LYS PRO VAL LEU ARG THR ALA 0.402685 0.71831
241 HIS SER ILE THR TYR LEU LEU PRO VAL 0.402439 0.706667
242 ILE LYS LEU GLU THR LYS LYS THR LYS LEU 0.401639 0.741935
243 THR SER ARG HIS LYS ALY LEU MET ALA 0.401274 0.774648
244 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.4 0.721519
245 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.4 0.753425
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5U98; Ligand: 1KX; Similar sites found with APoc: 185
This union binding pocket(no: 1) in the query (biounit: 5u98.bio2) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 4NS0 PIO None
2 1KGI T4A 2.3622
3 2GQS C2R 2.53165
4 3QRC SCR 2.54777
5 2Z77 HE7 2.8777
6 4D4U FUC GAL NAG 3.0303
7 4EKQ NPO 3.20856
8 2XG5 EC2 3.21101
9 2XG5 EC5 3.21101
10 4ZU4 4TG 3.37838
11 5UMY TNN 3.57143
12 4RYV ZEA 3.87097
13 1EC9 XYH 3.97112
14 3WG3 A2G GAL NAG FUC 4.0404
15 5UC4 83S 4.0404
16 4CJN QNZ 4.0404
17 4WVW SLT 4.16667
18 4XMF HSM 4.34783
19 1WW5 SGA BGC 4.375
20 1N5S ADL 4.46429
21 3ZXE PGZ 4.51128
22 5T7I LAT NAG GAL 4.51613
23 5GLT BGC GAL NAG GAL 5.05051
24 2Y24 XYP XYP GCV XYP 5.05051
25 3A16 PXO 5.05051
26 5U9J GER 5.05051
27 4KU7 PCG 5.05051
28 4IMO PWZ 5.11364
29 4ZSI GLP 5.26316
30 4OIT MAN 5.30973
31 6FOF LAT 5.61225
32 5NLD LBT 5.7554
33 2PFC PLM 6.01093
34 5TZO 7V7 6.06061
35 2WEI VGG 6.06061
36 6FXR AKG 6.06061
37 1Y7P RIP 6.06061
38 5L9V OGA 6.06061
39 1S5O 152 6.06061
40 1SDW IYT 6.06061
41 3A76 SPD 6.06061
42 5ZFJ 9BF 6.06061
43 3HQR OGA 6.06061
44 3NZ1 3NY 6.06061
45 5L9B AKG 6.06061
46 4X7Q 3YR 6.06061
47 1O9U ADZ 6.06061
48 5ZXD ATP 6.06061
49 1NVM OXL 6.06061
50 1QY1 PRZ 6.06061
51 4M8D 23J 6.06061
52 5NFB 8VT 6.25
53 4CLO XP0 6.4982
54 1NYW DAU 6.59898
55 1A78 TDG 6.71642
56 5B09 4MX 6.73077
57 3M3E GAL A2G NPO 6.8323
58 5DG2 GAL GLC 7.07071
59 2HRL SIA GAL SIA BGC NGA CEQ 7.07071
60 4WN5 MVC 7.07071
61 5LHT TIH 7.07071
62 5N0L ILE 7.07071
63 4Y8D 49J 7.07071
64 5E7G XYS BGC BGC XYS BGC XYS BGC BGC BGC 7.07071
65 3H7J PPY 7.07071
66 2VL1 GLY GLY 7.07071
67 5TVF CGQ 7.07071
68 1OPB RET 7.07071
69 4LCQ URQ 7.07071
70 3KYF 5GP 5GP 7.35931
71 1I7M PUT 7.46269
72 1I7M CG 7.46269
73 5MJA 7O3 7.58123
74 5C8W PCG 7.69231
75 4YLZ LAT NAG GAL 7.84314
76 3OCP CMP 7.91367
77 5X7Q GLC GLC GLC GLC GLC 7.94224
78 5X7Q GLC GLC GLC GLC 7.94224
79 4KBA 1QM 7.94224
80 4LIT AKG 8.08081
81 3JU6 ANP 8.08081
82 3H9A PPY 8.08081
83 3AVR OGA 8.08081
84 6HDT BTN 8.08081
85 5W10 CMP 8.08081
86 5INJ 6C7 8.08081
87 3WUD GLC GAL 8.08823
88 5HWV MBN 8.46154
89 3SXS PP2 9.09091
90 2Y6O 1N1 9.09091
91 4GQP B40 9.09091
92 3WBZ ATP 9.09091
93 6GQM F8H 9.09091
94 1U18 HSM 9.18919
95 3ZO7 K6H 9.57447
96 5XVG 8FX 9.74729
97 6F7X MFU 10
98 2HZQ STR 10.101
99 3GM5 CIT 10.101
100 3WUC GLC GAL 10.101
101 1OFL NGK GCD 10.101
102 5FYR INS 10.101
103 5ISY NAD 10.101
104 4PSR FUL 10.101
105 6E1Q CFA 10.101
106 5JWP AKG 10.101
107 2XUM OGA 10.101
108 6FA4 D1W 10.101
109 4H6B 10X 10.101
110 6GIN IR2 10.101
111 4BCS BTN 10.101
112 3P3N AKG 10.101
113 4CSD MFU 10.101
114 1SBR VIB 10.101
115 3FW3 ETS 10.1504
116 3RF4 FUN 10.3448
117 1TW4 CHD 10.4
118 4K55 H6P 10.4839
119 2BYC FMN 10.9489
120 5I0U DCY 11
121 5E5U 1PS 11.1111
122 3SAO NKN 11.1111
123 6D61 4AA 11.1111
124 1NKI PPF 11.1111
125 4Y24 TD2 11.1111
126 5HES 032 11.1111
127 1UMZ BGC BGC XYS BGC XYS GAL 11.1111
128 5H2U 1N1 11.1111
129 4HBM 0Y7 11.1111
130 1GZW GAL BGC 11.1111
131 2VN9 GVD 11.1111
132 6F6D AKG 11.1111
133 2CM4 RCL 11.3333
134 3ZGJ RMN 11.9134
135 1ULE GLA GAL NAG 12.1212
136 3GFZ FMN 12.1212
137 5V3D FCN 12.4138
138 6BU0 IHP 12.9771
139 5KJW 53C 12.9964
140 3NV3 GAL NAG MAN 13.0435
141 5MRH Q9Z 13.1313
142 2HO2 PRO PRO PRO PRO PRO PRO PRO PRO PRO LEU 13.1579
143 1YRX FMN 13.2231
144 5FUI APY 13.6364
145 1IS3 LAT 14.1414
146 5F6U 5VK 14.1414
147 1GQG DCD 14.1414
148 1NSZ GLC 14.1414
149 3AJH BL3 14.1414
150 6GNO XDI 14.8148
151 4QYN RTL 15.0376
152 3VV1 GAL FUC 15.1515
153 4YZ5 SLT 15.1515
154 5UXM TRP 15.1515
155 5KWW 6YA 15.1515
156 2IYG FMN 15.3226
157 1KJ1 MAN 15.5963
158 1J3R 6PG 16.1616
159 3K4Z CBI 16.1616
160 4D1J DGJ 16.1616
161 4LAX FK5 16.1616
162 2ET1 GLV 16.1616
163 5YBN AKG 16.1616
164 4JH6 FCN 16.6667
165 2P7Q GG6 17.1717
166 2A1L PCW 17.1717
167 1H2M OGA 17.3077
168 2ZHL NAG GAL GAL NAG 18.1818
169 3WV6 GAL BGC 18.1818
170 5O9W AKG 18.1818
171 3V99 ACD 18.1818
172 2QL9 CIT 18.5567
173 1LNX URI 19.7531
174 1BHX ASP PHE GLU GLU ILE 20
175 3NX2 FER 20.202
176 3W6G FLC 20.202
177 5N2D 8J8 21.5278
178 1H2K OGA 21.9512
179 4QXB OGA 22.2222
180 3O2K DST 22.2222
181 1LSH PLD 23.2323
182 2H8H H8H 23.2323
183 2D6M LBT 23.2704
184 5NIU 8YZ 24.2188
185 5EZU MYR 25.8427
Pocket No.: 2; Query (leader) PDB : 5U98; Ligand: VAL THR THR ASP ILE GLN VAL LYS VAL; Similar sites found with APoc: 99
This union binding pocket(no: 2) in the query (biounit: 5u98.bio2) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 4V1F BQ1 None
2 3KPE TM3 None
3 5N8V KZZ None
4 4WG0 CHD None
5 2CB8 MYA None
6 3KO0 TFP None
7 4F4S EFO None
8 6BR8 6OU 1.5873
9 6BR8 PGV 1.5873
10 2VWA PTY 2.0202
11 1HBK MYR 2.24719
12 4DE3 DN8 2.28137
13 2GWH PCI 3.2491
14 3RV5 DXC 3.37079
15 1DTL BEP 3.72671
16 5IUY BOG 4.0404
17 1FX8 BOG 4.0404
18 3E70 GDP 4.0404
19 1GNI OLA 4.0404
20 5UC4 83S 4.0404
21 1YC4 43P 4.0404
22 1A05 IPM 4.0404
23 2DC1 CIT 4.66102
24 4RC8 STE 4.95496
25 2WOR 2AN 5
26 2RH1 CLR 5.05051
27 2PSJ CEI 5.05051
28 4V3I ASP LEU THR ARG PRO 5.05837
29 3KYQ DPV 6.06061
30 3F8C HT1 6.06061
31 5NM7 GLY 6.06061
32 1ZOY UQ1 6.06061
33 4NAT 2W5 6.06061
34 4RW3 TDA 6.13718
35 1M2Z BOG 7.00389
36 2HHP FLC 7.07071
37 1NF8 BOG 7.07071
38 2D5X L35 7.0922
39 4ZVV NAD 7.22022
40 4ZVV GN0 7.22022
41 3DZ6 PUT 7.46269
42 1I7M PUT 7.46269
43 6CB2 OLC 8.08081
44 1XX4 BAM 8.08081
45 3FAL REA 8.08081
46 2OZ5 7XY 8.08081
47 3W54 RNB 8.08081
48 5FPN KYD 8.30325
49 5N26 CPT 8.79121
50 2VKL MLT 8.88889
51 2BHW NEX 9.09091
52 3T3Z 9PL 9.09091
53 2BCG GER 9.2233
54 4G86 BNT 9.38628
55 3GF2 SAL 9.58904
56 3KP6 SAL 9.93377
57 5I8F ML1 10.101
58 6DIO CIT 10.101
59 2HZQ STR 10.101
60 4URN NOV 10.101
61 5V3Y 5V8 10.1083
62 5XJ7 87O 10.4478
63 3RLF MAL 10.8303
64 4MGA 27L 11.1111
65 5K53 STE 11.1111
66 4TV1 36M 11.1111
67 4MG7 27H 11.1111
68 6CHP F0Y 11.8012
69 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 12.1212
70 5C1M OLC 12.1212
71 2YVE MBT 12.1212
72 4ZGM 32M 12.2951
73 2PX6 DH9 12.6354
74 3SFI 3SF 13.1313
75 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 13.3333
76 1LTI GAL 13.5922
77 1LT3 GAL BGC 13.5922
78 1LTT GAL BGC 13.5922
79 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 14.1414
80 3WYJ H78 14.1414
81 4IBF 1D5 15.1515
82 3O01 DXC 15.1625
83 1TV5 N8E 16.1616
84 5ZCO PEK 16.1616
85 1I0B PEL 16.6065
86 3RGZ BLD 17.1717
87 5LX9 OLB 18.1818
88 5LWY OLB 18.1818
89 4DK7 0KS 18.1818
90 5V4R MGT 20.9877
91 1TO9 HMH 22.2222
92 2QCX PF1 22.2222
93 4OGQ 7PH 23.5294
94 4OGQ UMQ 23.5294
95 6GMN F4E 24.0385
96 5OCA 9QZ 28.2828
97 1GVE CIT 28.2828
98 1HK8 DGT 30.303
99 5VRH OLB 32.3232
Pocket No.: 3; Query (leader) PDB : 5U98; Ligand: 1KX; Similar sites found with APoc: 437
This union binding pocket(no: 3) in the query (biounit: 5u98.bio1) has 68 residues
No: Leader PDB Ligand Sequence Similarity
1 1NU4 MLA None
2 1UO5 PIH None
3 4F4S EFO None
4 4WG0 CHD None
5 5N8V KZZ None
6 3KO0 TFP None
7 1UO4 PIH None
8 6BR8 PGV 1.5873
9 4HK8 XYP XYP XYP XYP XYP XYP 1.5873
10 1PZL MYR 1.68776
11 4RT1