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Receptor
PDB id Resolution Class Description Source Keywords
5VW2 1.45 Å EC: 1.18.1.2 NADPH SOAK OF Y316S MUTANT OF CORN ROOT FERREDOXIN:NADP+ RED ZEA MAYS FLAVOENZYME HYDRIDE TRANSFER PHOTOSYNTHESIS ACTIVE SITE COMPRESSION TRANSFERASE OXIDOREDUCTASE
Ref.: HIGH-RESOLUTION STUDIES OF HYDRIDE TRANSFER IN THE FERREDOXIN:NADP(+) REDUCTASE SUPERFAMILY. FEBS J. V. 284 3302 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:401;
Invalid;
none;
submit data
24.305 Mg [Mg+2...
ACT A:402;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
NAP A:404;
Valid;
Atoms found LESS than expected: % Diff = 0;
Kd < 0.02 uM
743.405 C21 H28 N7 O17 P3 c1cc(...
FDA A:403;
Valid;
none;
submit data
787.566 C27 H35 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5VW2 1.45 Å EC: 1.18.1.2 NADPH SOAK OF Y316S MUTANT OF CORN ROOT FERREDOXIN:NADP+ RED ZEA MAYS FLAVOENZYME HYDRIDE TRANSFER PHOTOSYNTHESIS ACTIVE SITE COMPRESSION TRANSFERASE OXIDOREDUCTASE
Ref.: HIGH-RESOLUTION STUDIES OF HYDRIDE TRANSFER IN THE FERREDOXIN:NADP(+) REDUCTASE SUPERFAMILY. FEBS J. V. 284 3302 2017
Members (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 25 families.
1 1JB9 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 5VW9 - NCA C6 H6 N2 O c1cc(cnc1)....
3 5VW8 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 5H59 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 5VW3 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
6 5VW6 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 3LO8 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
8 5VWA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
9 3LVB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
10 5VW4 - NCA C6 H6 N2 O c1cc(cnc1)....
11 5VW7 - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
12 5VWB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
13 5VW2 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
14 5VW5 - NCA C6 H6 N2 O c1cc(cnc1)....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 1JB9 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 5VW9 - NCA C6 H6 N2 O c1cc(cnc1)....
3 5VW8 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 5H59 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 5VW3 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
6 5VW6 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 3LO8 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
8 5VWA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
9 3LVB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
10 5VW4 - NCA C6 H6 N2 O c1cc(cnc1)....
11 5VW7 - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
12 5VWB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
13 5VW2 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
14 5VW5 - NCA C6 H6 N2 O c1cc(cnc1)....
50% Homology Family (60)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 1JB9 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 5VW9 - NCA C6 H6 N2 O c1cc(cnc1)....
3 5VW8 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 5H59 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 5VW3 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
6 5VW6 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 3LO8 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
8 5VWA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
9 3LVB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
10 5VW4 - NCA C6 H6 N2 O c1cc(cnc1)....
11 5VW7 - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
12 5VWB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
13 5VW2 Kd < 0.02 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
14 5VW5 - NCA C6 H6 N2 O c1cc(cnc1)....
15 2RC5 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
16 1QFZ - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
17 1QFY Kd < 0.2 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
18 1QGA Kd = 5.5 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
19 1QG0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
20 1E63 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
21 1H42 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
22 1E62 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
23 1H85 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
24 2X3U - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
25 1B2R - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
26 1GO2 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
27 1QUE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
28 4C43 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
29 1E64 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
30 3ZC3 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
31 1GR1 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
32 1QGY - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
33 1QGZ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
34 3ZBT - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
35 2BSA Kd < 0.01 uM NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
36 1W34 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
37 2VZL Kd = 550 uM NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
38 1QH0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
39 1BQE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
40 1OGJ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
41 1BJK - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
42 1OGI - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
43 1W35 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
44 4BPR - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
45 1GJR - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
46 2BMW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
47 2VYQ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
48 3ZBU - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
49 1QUF - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
50 1GAW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
51 1FNB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
52 1BX1 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
53 1FRN - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
54 1FNC - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
55 1FRQ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
56 1BX0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
57 1FND - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
58 1SM4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
59 3VO2 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
60 3VO1 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAP; Similar ligands found: 123
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NHD 0.68254 0.958904
10 NJP 0.661417 0.972973
11 NFD 0.658915 0.934211
12 NXX 0.619048 0.959459
13 DND 0.619048 0.959459
14 AMP NAD 0.606061 0.958904
15 ZID 0.605839 0.972603
16 NAQ 0.59854 0.922078
17 ATR 0.59292 0.917808
18 NAE 0.591241 0.946667
19 NDE 0.58042 0.986301
20 A22 0.571429 0.958904
21 NAJ 0.567164 0.986111
22 A2R 0.563025 0.932432
23 NDC 0.561644 0.922078
24 NA7 0.552846 0.907895
25 ODP 0.551471 0.935065
26 A2P 0.539823 0.930556
27 8ID 0.537313 0.910256
28 NPW 0.525547 0.8875
29 NZQ 0.521739 0.910256
30 CNA 0.521739 0.959459
31 NDP 0.514493 0.922078
32 PO4 PO4 A A A A PO4 0.503937 0.930556
33 1DG 0.503401 0.922078
34 DG1 0.503401 0.922078
35 TXP 0.5 0.922078
36 NMN AMP PO4 0.492958 0.921053
37 XNP 0.492958 0.875
38 25L 0.492308 0.958904
39 25A 0.492063 0.972222
40 NMN 0.486726 0.888889
41 NGD 0.485714 0.935065
42 9JJ 0.481707 0.8875
43 2AM 0.477876 0.891892
44 ADP 0.458333 0.945205
45 PAP 0.451613 0.931507
46 A2D 0.445378 0.945205
47 AN2 0.442623 0.932432
48 7L1 0.441558 0.777778
49 ADP PO3 0.44 0.944444
50 SAP 0.44 0.896104
51 AGS 0.44 0.896104
52 M33 0.439024 0.906667
53 AR6 AR6 0.438849 0.945205
54 BA3 0.438017 0.945205
55 OAD 0.43609 0.92
56 ADP BMA 0.43609 0.92
57 DQV 0.435714 0.958904
58 HEJ 0.435484 0.945205
59 ATP 0.435484 0.945205
60 OOB 0.435115 0.958904
61 B4P 0.434426 0.945205
62 AP5 0.434426 0.945205
63 GAP 0.433071 0.92
64 0WD 0.432432 0.922078
65 2A5 0.432 0.87013
66 5FA 0.432 0.945205
67 AQP 0.432 0.945205
68 AT4 0.430894 0.907895
69 00A 0.428571 0.909091
70 DAL AMP 0.427481 0.932432
71 CA0 0.427419 0.92
72 ADP ALF 0.426357 0.871795
73 ALF ADP 0.426357 0.871795
74 9X8 0.425373 0.871795
75 ACP 0.424 0.92
76 NAJ PZO 0.423841 0.897436
77 9SN 0.423358 0.897436
78 ADP VO4 0.423077 0.932432
79 VO4 ADP 0.423077 0.932432
80 WAQ 0.422222 0.884615
81 V3L 0.421875 0.945205
82 ACQ 0.421875 0.92
83 ADQ 0.421053 0.92
84 AR6 0.420635 0.918919
85 APR 0.420635 0.918919
86 ATP A A A 0.42029 0.958333
87 CO7 0.419753 0.786517
88 3OD 0.419118 0.92
89 1ZZ 0.419118 0.841463
90 DLL 0.41791 0.958904
91 AD9 0.417323 0.92
92 NAX 0.416667 0.875
93 OVE 0.416667 0.857143
94 MYR AMP 0.416058 0.841463
95 AV2 0.415385 0.868421
96 A3P 0.414634 0.944444
97 NNR 0.414414 0.72973
98 OMR 0.413793 0.831325
99 6YZ 0.412214 0.92
100 ANP 0.410853 0.92
101 A1R 0.410448 0.860759
102 ABM 0.409836 0.893333
103 A 0.408333 0.944444
104 AMP 0.408333 0.944444
105 SON 0.408 0.933333
106 PPS 0.407692 0.829268
107 5AL 0.407692 0.932432
108 NAI 0.406897 0.909091
109 7D3 0.406504 0.857143
110 ADX 0.404762 0.829268
111 ATF 0.40458 0.907895
112 3UK 0.404412 0.945946
113 TYR AMP 0.404255 0.921053
114 AMP DBH 0.404255 0.894737
115 139 0.402685 0.875
116 50T 0.401575 0.906667
117 SRP 0.401515 0.907895
118 A A 0.40146 0.972222
119 B5V 0.40146 0.933333
120 A3R 0.4 0.860759
121 3AM 0.4 0.90411
122 B5M 0.4 0.921053
123 FA5 0.4 0.933333
Ligand no: 2; Ligand: FDA; Similar ligands found: 141
No: Ligand ECFP6 Tc MDL keys Tc
1 FDA 1 1
2 FNK 0.691781 0.965517
3 F2N 0.647436 0.976744
4 FAS 0.641892 0.906977
5 FAD 0.641892 0.906977
6 SFD 0.630872 0.787879
7 6FA 0.61745 0.896552
8 6YU 0.586207 0.903226
9 RFL 0.585987 0.876405
10 FAD NBT 0.584906 0.902174
11 FAY 0.579618 0.895349
12 62F 0.573248 0.895349
13 FA9 0.554217 0.918605
14 FAD CNX 0.551515 0.873684
15 P5F 0.545455 0.920455
16 FNR 0.532258 0.892857
17 FAD NBA 0.526012 0.873684
18 A2D 0.516667 0.833333
19 AR6 0.5 0.811765
20 APR 0.5 0.811765
21 M33 0.496 0.823529
22 BA3 0.495935 0.833333
23 P6G FDA 0.494186 0.827957
24 B4P 0.491935 0.833333
25 AP5 0.491935 0.833333
26 ANP 0.488372 0.813953
27 AGS 0.484375 0.795455
28 SAP 0.484375 0.795455
29 HEJ 0.480315 0.833333
30 ATP 0.480315 0.833333
31 ADP 0.48 0.833333
32 48N 0.479167 0.818182
33 FB0 0.478261 0.819149
34 AQP 0.476562 0.833333
35 5FA 0.476562 0.833333
36 AT4 0.47619 0.804598
37 AN2 0.47619 0.823529
38 GTA 0.475524 0.831461
39 AD9 0.472868 0.813953
40 3OD 0.471014 0.835294
41 FAE 0.46988 0.896552
42 ATF 0.469697 0.804598
43 AP0 0.469388 0.860465
44 ACP 0.46875 0.835294
45 OAD 0.467153 0.835294
46 9X8 0.467153 0.795455
47 PAJ 0.463235 0.808989
48 A1R 0.463235 0.827586
49 A3R 0.463235 0.827586
50 G3A 0.461538 0.83908
51 T5A 0.46 0.896552
52 A22 0.459259 0.845238
53 G5P 0.458333 0.83908
54 6YZ 0.455224 0.835294
55 DQV 0.455172 0.845238
56 ACQ 0.454545 0.835294
57 PRX 0.453846 0.793103
58 5AL 0.451128 0.823529
59 ADX 0.449612 0.741935
60 CA0 0.449612 0.813953
61 50T 0.446154 0.802326
62 8QN 0.445255 0.823529
63 ABM 0.444444 0.790698
64 A 0.443548 0.809524
65 AMP 0.443548 0.809524
66 TXE 0.442953 0.892857
67 OMR 0.442953 0.782609
68 ADQ 0.442029 0.813953
69 AMO 0.442029 0.825581
70 ADJ 0.440789 0.822222
71 139 0.440789 0.862069
72 B5M 0.440559 0.837209
73 BIS 0.439716 0.786517
74 PTJ 0.439716 0.818182
75 ME8 0.439716 0.771739
76 TXA 0.439716 0.825581
77 AFH 0.438356 0.788889
78 A4P 0.437086 0.876405
79 6V0 0.436242 0.882353
80 UP5 0.436242 0.880952
81 TXD 0.436242 0.870588
82 DND 0.436242 0.825581
83 NXX 0.436242 0.825581
84 5SV 0.434783 0.758242
85 SRP 0.433824 0.804598
86 4AD 0.431655 0.816092
87 B5Y 0.430556 0.837209
88 P1H 0.430303 0.842697
89 FYA 0.429577 0.823529
90 AHX 0.428571 0.797753
91 SRA 0.428571 0.772727
92 P33 FDA 0.427778 0.821053
93 MAP 0.427536 0.795455
94 AU1 0.427481 0.813953
95 NAI 0.426667 0.870588
96 25L 0.426573 0.845238
97 AP2 0.426357 0.825581
98 A12 0.426357 0.825581
99 CNV FAD 0.426136 0.876405
100 EAD 0.423313 0.862069
101 COD 0.423077 0.806452
102 PR8 0.422535 0.8
103 T99 0.422222 0.804598
104 TAT 0.422222 0.804598
105 APC 0.421053 0.825581
106 4TC 0.421053 0.882353
107 NB8 0.41958 0.797753
108 1ZZ 0.41958 0.771739
109 4UU 0.418919 0.837209
110 GA7 0.418919 0.825581
111 00A 0.41844 0.786517
112 ADV 0.41791 0.804598
113 RBY 0.41791 0.804598
114 A3D 0.417722 0.835294
115 NAX 0.417219 0.862069
116 OOB 0.414286 0.823529
117 25A 0.414286 0.833333
118 LAD 0.412587 0.788889
119 UPA 0.411765 0.870588
120 CNA 0.410256 0.825581
121 80F 0.408805 0.833333
122 DLL 0.408451 0.823529
123 XAH 0.408163 0.771739
124 4UW 0.407895 0.829545
125 F2R 0.407643 0.793478
126 ADP PO3 0.407407 0.788235
127 DAL AMP 0.407143 0.802326
128 3UK 0.405594 0.835294
129 4UV 0.405405 0.837209
130 TYM 0.405229 0.825581
131 NAD 0.405063 0.823529
132 9ZD 0.404255 0.827586
133 9ZA 0.404255 0.827586
134 9SN 0.40411 0.797753
135 VO4 ADP 0.402878 0.781609
136 ADP VO4 0.402878 0.781609
137 WAQ 0.402778 0.806818
138 B5V 0.402778 0.825581
139 YAP 0.401361 0.816092
140 FA5 0.401361 0.825581
141 YLP 0.401316 0.793478
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5VW2; Ligand: NAP; Similar sites found with APoc: 164
This union binding pocket(no: 1) in the query (biounit: 5vw2.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 2CHT TSA None
2 5KK4 44E None
3 4CQK PIO None
4 5OVK NDP 1.17188
5 2HIM ASP 1.89873
6 2HIM ASN 1.89873
7 4BWL MN9 1.97368
8 2WPB ZZI 1.97368
9 4RHY 3QG 1.99005
10 1NE7 16G 2.07612
11 5HRA DAS 2.12766
12 4F97 GDP 2.21519
13 2YX1 SFG 2.21519
14 5VKM GAL SIA 2.21519
15 1Y7P RIP 2.24215
16 4CP8 MLI 2.25873
17 4BHN BH9 2.53165
18 1XNG ATP 2.61194
19 5YSI NCA 2.63158
20 1O5O U5P 2.71493
21 5D63 FUC GAL GLA 2.73038
22 4M6T SAM 2.73224
23 6B2M COA 2.7972
24 1T9M FMN 2.80374
25 3FSY SCA 2.8481
26 3A23 GAL 2.8481
27 2JK0 ASP 2.8481
28 2V7B BEZ 2.8481
29 5KZD RCJ 3.07167
30 3VSV XYS 3.16456
31 4A59 AMP 3.16456
32 2RC8 DSN 3.40136
33 5KOD IAC 3.48101
34 3K0T BGC 3.4965
35 3FIU POP 3.61446
36 5DCH 1YO 3.64583
37 1M0S CIT 3.65297
38 6BMN PAP 3.72881
39 1RZU ADP 3.79747
40 4CUB GAL NAG 3.82514
41 4TVD BGC 4.11392
42 3MQ2 SAH 4.12844
43 3SJK LYS PRO VAL LEU ARG THR ALA 4.21053
44 4ZDM GLY 4.21456
45 2CBZ ATP 4.21941
46 3O7J 2AL 4.2328
47 3B9Q MLI 4.30464
48 5OCS CIT 4.43038
49 3QPB URA 4.60993
50 3QPB R1P 4.60993
51 4HMX FMN 4.65116
52 4HMX WUB 4.65116
53 4F07 FAD 4.73684
54 2RH1 CLR 4.74684
55 3THR C2F 4.77816
56 2RCA GLY 4.79452
57 5GQI CTP 4.8583
58 5OFW 9TW 4.93274
59 2GJP MAL 5.06329
60 6AR9 3L4 5.14706
61 4NS0 PIO 5.26316
62 5FUI APY 5.30303
63 5UCD NAP 5.37975
64 5IRN ADP 5.37975
65 5L8N 6RQ 5.46875
66 5ZXD ATP 5.67766
67 3BY9 SIN 5.76923
68 2VSS ACO 5.7971
69 1WLJ U5P 5.82011
70 6GEH FAD 5.85938
71 1KZL CRM 6.25
72 5EHS 5OY 6.34328
73 5EHS 2JJ 6.34328
74 1S68 AMP 6.4257
75 5WHT SIA GAL 6.52174
76 5WHT SIA GAL GLC 6.52174
77 5WHT SIA 6.52174
78 2BVE PH5 6.72269
79 1QK3 5GP 6.86695
80 5ZA2 NXL 6.96203
81 1KQR MNA 7.26257
82 6MJ7 ARG 7.27273
83 2BOS GLA GAL GLC NBU 7.35294
84 2BOS GLA GAL GLC 7.35294
85 4RHS SIA SIA GAL 7.37705
86 2WG9 OCA 7.69231
87 2ZQO NGA 7.69231
88 1P19 IMP 7.69231
89 4ONT SIA GAL BGC 7.75194
90 5O0X FAD 7.90378
91 4DS0 A2G GAL NAG FUC 7.97546
92 3COB ADP 8.22785
93 6AC9 ANP 8.22785
94 3RK0 AMP 8.43882
95 5LNE A2G GAL 8.53659
96 1RJW ETF 8.5443
97 6A4R ASP 8.67924
98 4LO6 SIA GAL 8.94737
99 3P13 RIP 9.02778
100 4YHB FAD 9.15751
101 4YRY NAD 9.42029
102 4YRY FAD 9.42029
103 3QDW NDG 9.79021
104 3QDY CBS 9.79021
105 3QDU CBS CBS 9.79021
106 5YLY FAD 9.93151
107 4G6I RS3 10
108 4AG5 ADP 10.1266
109 3IWD M2T 10.2941
110 5K7U SAM 10.6667
111 5IL1 SAM 11.3208
112 5K6A 6QT 11.4583
113 4EOY ASN ASP TRP LEU LEU PRO SER TYR 11.7188
114 3HY2 ATP 11.8182
115 3RKR NAP 12.5954
116 5E6O TRP GLU GLU LEU 12.7119
117 5JCA FAD 13.0282
118 3CRZ NAP 13.2296
119 3CRZ FAD 13.2296
120 6GNO XDI 13.3333
121 4KGM ATP 13.8776
122 1N13 AG2 14.1593
123 3OZV FAD 14.2405
124 3OZV ECN 14.2405
125 2QQC AG2 14.2857
126 3A3B FMN 14.7368
127 3A3B RBF 14.7368
128 1SQL GUN 15.0685
129 1EP2 FAD 15.3257
130 4ZES MMA 15.6463
131 1PVC ILE SER GLU VAL 16.1765
132 3W2E FAD 16.2362
133 3W2E NAD 16.2362
134 5OQW A4E 16.5354
135 2WEL K88 16.6667
136 4KSY 1SY 18.595
137 4WQM FAD 19.3038
138 1KRH FAD 20.5696
139 2PIA FMN 21.8354
140 1A8P FAD 22.093
141 2CND FAD 22.963
142 1QX4 FAD 24.0876
143 2QTZ FAD 25.3165
144 2QTZ NAP 25.3165
145 5OGX FAD 26.2658
146 3CB0 FMN 26.5896
147 2EIX FAD 27.1605
148 4DQL NAP 27.2152
149 4DQL FAD 27.2152
150 1TLL FAD 28.481
151 1TLL NAP 28.481
152 1F20 FAD 28.481
153 1F20 NAP 28.481
154 4G1V FAD 28.7975
155 4U9U FAD 30.9609
156 4KJU 1RH 31.3953
157 3FJO FAD 31.962
158 3QFS FAD 31.962
159 3QFS NAP 31.962
160 5FA6 FAD 31.962
161 5FA6 FMN 31.962
162 5FA6 NAP 31.962
163 5GXU FAD 31.962
164 1DDG FAD 38.2911
Pocket No.: 2; Query (leader) PDB : 5VW2; Ligand: FDA; Similar sites found with APoc: 164
This union binding pocket(no: 2) in the query (biounit: 5vw2.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 2CHT TSA None
2 5KK4 44E None
3 4CQK PIO None
4 5OVK NDP 1.17188
5 2HIM ASP 1.89873
6 2HIM ASN 1.89873
7 4BWL MN9 1.97368
8 2WPB ZZI 1.97368
9 4RHY 3QG 1.99005
10 1NE7 16G 2.07612
11 5HRA DAS 2.12766
12 4F97 GDP 2.21519
13 2YX1 SFG 2.21519
14 5VKM GAL SIA 2.21519
15 1Y7P RIP 2.24215
16 4CP8 MLI 2.25873
17 4BHN BH9 2.53165
18 1XNG ATP 2.61194
19 5YSI NCA 2.63158
20 1O5O U5P 2.71493
21 5D63 FUC GAL GLA 2.73038
22 4M6T SAM 2.73224
23 6B2M COA 2.7972
24 1T9M FMN 2.80374
25 3FSY SCA 2.8481
26 3A23 GAL 2.8481
27 2JK0 ASP 2.8481
28 2V7B BEZ 2.8481
29 5KZD RCJ 3.07167
30 3VSV XYS 3.16456
31 4A59 AMP 3.16456
32 2RC8 DSN 3.40136
33 5KOD IAC 3.48101
34 3K0T BGC 3.4965
35 3FIU POP 3.61446
36 5DCH 1YO 3.64583
37 1M0S CIT 3.65297
38 6BMN PAP 3.72881
39 1RZU ADP 3.79747
40 4CUB GAL NAG 3.82514
41 4TVD BGC 4.11392
42 3MQ2 SAH 4.12844
43 3SJK LYS PRO VAL LEU ARG THR ALA 4.21053
44 4ZDM GLY 4.21456
45 2CBZ ATP 4.21941
46 3O7J 2AL 4.2328
47 3B9Q MLI 4.30464
48 5OCS CIT 4.43038
49 3QPB URA 4.60993
50 3QPB R1P 4.60993
51 4HMX FMN 4.65116
52 4HMX WUB 4.65116
53 4F07 FAD 4.73684
54 2RH1 CLR 4.74684
55 3THR C2F 4.77816
56 2RCA GLY 4.79452
57 5GQI CTP 4.8583
58 5OFW 9TW 4.93274
59 2GJP MAL 5.06329
60 6AR9 3L4 5.14706
61 4NS0 PIO 5.26316
62 5FUI APY 5.30303
63 5UCD NAP 5.37975
64 5IRN ADP 5.37975
65 5L8N 6RQ 5.46875
66 5ZXD ATP 5.67766
67 3BY9 SIN 5.76923
68 2VSS ACO 5.7971
69 1WLJ U5P 5.82011
70 6GEH FAD 5.85938
71 1KZL CRM 6.25
72 5EHS 2JJ 6.34328
73 5EHS 5OY 6.34328
74 1S68 AMP 6.4257
75 5WHT SIA GAL 6.52174
76 5WHT SIA GAL GLC 6.52174
77 5WHT SIA 6.52174
78 2BVE PH5 6.72269
79 1QK3 5GP 6.86695
80 5ZA2 NXL 6.96203
81 1KQR MNA 7.26257
82 6MJ7 ARG 7.27273
83 2BOS GLA GAL GLC NBU 7.35294
84 2BOS GLA GAL GLC 7.35294
85 4RHS SIA SIA GAL 7.37705
86 2WG9 OCA 7.69231
87 2ZQO NGA 7.69231
88 1P19 IMP 7.69231
89 4ONT SIA GAL BGC 7.75194
90 5O0X FAD 7.90378
91 4DS0 A2G GAL NAG FUC 7.97546
92 3COB ADP 8.22785
93 6AC9 ANP 8.22785
94 3RK0 AMP 8.43882
95 5LNE A2G GAL 8.53659
96 1RJW ETF 8.5443
97 6A4R ASP 8.67924
98 4LO6 SIA GAL 8.94737
99 3P13 RIP 9.02778
100 4YHB FAD 9.15751
101 4YRY NAD 9.42029
102 4YRY FAD 9.42029
103 3QDW NDG 9.79021
104 3QDY CBS 9.79021
105 3QDU CBS CBS 9.79021
106 5YLY FAD 9.93151
107 4G6I RS3 10
108 4AG5 ADP 10.1266
109 3IWD M2T 10.2941
110 5K7U SAM 10.6667
111 5IL1 SAM 11.3208
112 5K6A 6QT 11.4583
113 4EOY ASN ASP TRP LEU LEU PRO SER TYR 11.7188
114 3HY2 ATP 11.8182
115 3RKR NAP 12.5954
116 5E6O TRP GLU GLU LEU 12.7119
117 5JCA FAD 13.0282
118 3CRZ NAP 13.2296
119 3CRZ FAD 13.2296
120 6GNO XDI 13.3333
121 4KGM ATP 13.8776
122 1N13 AG2 14.1593
123 3OZV FAD 14.2405
124 3OZV ECN 14.2405
125 2QQC AG2 14.2857
126 3A3B FMN 14.7368
127 3A3B RBF 14.7368
128 1SQL GUN 15.0685
129 1EP2 FAD 15.3257
130 4ZES MMA 15.6463
131 1PVC ILE SER GLU VAL 16.1765
132 3W2E FAD 16.2362
133 3W2E NAD 16.2362
134 5OQW A4E 16.5354
135 2WEL K88 16.6667
136 4KSY 1SY 18.595
137 4WQM FAD 19.3038
138 1KRH FAD 20.5696
139 2PIA FMN 21.8354
140 1A8P FAD 22.093
141 2CND FAD 22.963
142 1QX4 FAD 24.0876
143 2QTZ FAD 25.3165
144 2QTZ NAP 25.3165
145 5OGX FAD 26.2658
146 3CB0 FMN 26.5896
147 2EIX FAD 27.1605
148 4DQL NAP 27.2152
149 4DQL FAD 27.2152
150 1TLL FAD 28.481
151 1TLL NAP 28.481
152 1F20 FAD 28.481
153 1F20 NAP 28.481
154 4G1V FAD 28.7975
155 4U9U FAD 30.9609
156 4KJU 1RH 31.3953
157 3FJO FAD 31.962
158 3QFS FAD 31.962
159 3QFS NAP 31.962
160 5FA6 FAD 31.962
161 5FA6 FMN 31.962
162 5FA6 NAP 31.962
163 5GXU FAD 31.962
164 1DDG FAD 38.2911
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