Receptor
PDB id Resolution Class Description Source Keywords
5V13 1.84 Å NON-ENZYME: BINDING MOSQUITO JUVENILE HORMONE-BINDING PROTEIN AEDES AEGYPTI ODORANT-BINDING PROTEIN AEDES ANOPHELES CULEX D7 HORMONPROTEIN
Ref.: A MOSQUITO HEMOLYMPH ODORANT-BINDING PROTEIN FAMILY SPECIFICALLY BINDS JUVENILE HORMONE. J. BIOL. CHEM. V. 292 15329 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
JH3 B:301;
A:301;
C:301;
Valid;
Valid;
Valid;
none;
none;
none;
Kd = 23.3 nM
266.376 C16 H26 O3 C/C(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5V13 1.84 Å NON-ENZYME: BINDING MOSQUITO JUVENILE HORMONE-BINDING PROTEIN AEDES AEGYPTI ODORANT-BINDING PROTEIN AEDES ANOPHELES CULEX D7 HORMONPROTEIN
Ref.: A MOSQUITO HEMOLYMPH ODORANT-BINDING PROTEIN FAMILY SPECIFICALLY BINDS JUVENILE HORMONE. J. BIOL. CHEM. V. 292 15329 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 552 families.
1 5V13 Kd = 23.3 nM JH3 C16 H26 O3 C/C(=CCC/C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 426 families.
1 5V13 Kd = 23.3 nM JH3 C16 H26 O3 C/C(=CCC/C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 322 families.
1 5V13 Kd = 23.3 nM JH3 C16 H26 O3 C/C(=CCC/C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: JH3; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 JH3 1 1
2 2TX 0.553571 0.8
Similar Ligands (3D)
Ligand no: 1; Ligand: JH3; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5V13; Ligand: JH3; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5v13.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5V13; Ligand: JH3; Similar sites found with APoc: 1
This union binding pocket(no: 2) in the query (biounit: 5v13.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 5Z84 CHD 23.2143
Pocket No.: 3; Query (leader) PDB : 5V13; Ligand: JH3; Similar sites found with APoc: 1
This union binding pocket(no: 3) in the query (biounit: 5v13.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 5Z84 CHD 23.2143
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