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Receptor
PDB id Resolution Class Description Source Keywords
5UDS 2.37 Å NON-ENZYME: OTHER LARE, A SULFUR TRANSFERASE INVOLVED IN SYNTHESIS OF THE COFA LACTATE RACEMASE, IN COMPLEX WITH MGATP LACTOBACILLUS PLANTARUM (STRAIN ATCC BNCIMB 8826 / WCFS1) LAR SULFUR TRANSFERASE LARE AMPYLATION HEXAMER TRIMER ATP MAGNESIUM ATP PYROPHOPHATASE DOMAIN LACTATE LACTATERACEMIZATION LACTATE RACEMASE TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM OF SACRIFICIAL SULFUR INSERTASE OF THE N-TYPE ATP PYROPHOSPHATASE FAMILY, LARE. PROC. NATL. ACAD. SCI. V. 114 9074 2017 U.S.A.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 D:503;
A:503;
F:503;
C:503;
B:503;
E:503;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
ATP C:501;
A:501;
F:501;
B:501;
D:501;
E:501;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
507.181 C10 H16 N5 O13 P3 c1nc(...
MG E:502;
C:502;
A:502;
D:502;
B:502;
F:502;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6B2M 2.09 Å NON-ENZYME: OTHER LARE, A SULFUR TRANSFERASE INVOLVED IN SYNTHESIS OF THE COFA LACTATE RACEMASE IN COMPLEX WITH COENZYME A LACTOBACILLUS PLANTARUM LAR SULFUR TRANSFERASE LARE AMPYLATION HEXAMER TRIMER ATP MAGNESIUM ATP PYROPHOPHATASE DOMAIN LACTATE LACTATERACEMIZATION LACTATE RACEMASE COENZYME A TRANSFERASE
Ref.: ANALYSIS OF THE ACTIVE SITE CYSTEINE RESIDUE OF THE SACRIFICIAL SULFUR INSERTASE LARE FROM LACTOBACILLU PLANTARUM. BIOCHEMISTRY V. 57 5513 2018
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5UDS - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 6B2M - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5UDS - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 6B2M - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5UDS - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 6B2M - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ATP; Similar ligands found: 422
No: Ligand ECFP6 Tc MDL keys Tc
1 HEJ 1 1
2 ATP 1 1
3 5FA 0.985507 1
4 AQP 0.985507 1
5 AP5 0.927536 0.971831
6 B4P 0.927536 0.971831
7 BA3 0.913043 0.971831
8 ADP 0.9 1
9 A2D 0.884058 0.971831
10 AGS 0.84 0.945946
11 SAP 0.84 0.945946
12 6YZ 0.833333 0.972222
13 AT4 0.810811 0.958904
14 AN2 0.810811 0.985915
15 25L 0.809524 0.985915
16 AR6 0.802632 0.971831
17 APR 0.802632 0.971831
18 M33 0.8 0.958333
19 ACQ 0.794872 0.972222
20 TAT 0.794872 0.958904
21 T99 0.794872 0.958904
22 AD9 0.792208 0.972222
23 ACP 0.789474 0.972222
24 AMP 0.788732 0.971429
25 A 0.788732 0.971429
26 ANP 0.772152 0.972222
27 CA0 0.753247 0.945205
28 ADX 0.753247 0.873418
29 A22 0.746988 0.985915
30 50T 0.74359 0.958333
31 PRX 0.734177 0.893333
32 APC 0.734177 0.958904
33 ABM 0.733333 0.917808
34 ATF 0.731707 0.958904
35 ITT 0.730769 0.943662
36 7D4 0.730769 0.905405
37 ADQ 0.729412 0.945205
38 A3R 0.729412 0.907895
39 AP2 0.714286 0.958904
40 A12 0.714286 0.958904
41 A1R 0.709302 0.907895
42 SRA 0.706667 0.918919
43 5AL 0.698795 0.931507
44 HFD 0.695122 0.945946
45 9X8 0.693182 0.92
46 OAD 0.693182 0.945205
47 AU1 0.6875 0.972222
48 SRP 0.682353 0.906667
49 G5P 0.680851 0.921053
50 25A 0.678161 0.971831
51 3OD 0.677778 0.945205
52 4AD 0.670455 0.92
53 G3A 0.670213 0.921053
54 00A 0.662921 0.883117
55 RBY 0.662651 0.932432
56 ADP PO3 0.662651 0.943662
57 ADV 0.662651 0.932432
58 BIS 0.659341 0.933333
59 8QN 0.659091 0.931507
60 5SV 0.659091 0.848101
61 OOB 0.659091 0.931507
62 GTA 0.65625 0.886076
63 UP5 0.653061 0.92
64 AMO 0.651685 0.932432
65 PAJ 0.651685 0.884615
66 2A5 0.650602 0.918919
67 MAP 0.647727 0.945946
68 3AT 0.647059 0.971831
69 AHX 0.644444 0.896104
70 DLL 0.644444 0.931507
71 ATR 0.642857 0.971429
72 PAP 0.642857 0.985714
73 PTJ 0.641304 0.896104
74 7D3 0.6375 0.905405
75 3UK 0.637363 0.918919
76 SON 0.634146 0.932432
77 A4P 0.633663 0.843373
78 ALF ADP 0.632184 0.87013
79 ADP ALF 0.632184 0.87013
80 PR8 0.630435 0.85
81 WAQ 0.630435 0.883117
82 LAD 0.630435 0.860759
83 B5V 0.630435 0.906667
84 AFH 0.628866 0.884615
85 LMS 0.628205 0.82716
86 GAP 0.627907 0.893333
87 DTP 0.627907 0.905405
88 VO4 ADP 0.625 0.931507
89 ADP VO4 0.625 0.931507
90 TXA 0.623656 0.932432
91 ME8 0.623656 0.839506
92 1ZZ 0.623656 0.839506
93 NB8 0.623656 0.896104
94 FYA 0.623656 0.905405
95 DQV 0.622449 0.958333
96 T5A 0.621359 0.841463
97 ADN 0.619718 0.84507
98 RAB 0.619718 0.84507
99 XYA 0.619718 0.84507
100 DAL AMP 0.611111 0.905405
101 9SN 0.610526 0.871795
102 48N 0.61 0.896104
103 AP0 0.607843 0.896104
104 9ZD 0.604396 0.907895
105 9ZA 0.604396 0.907895
106 FA5 0.604167 0.906667
107 B5M 0.604167 0.894737
108 YAP 0.604167 0.894737
109 B5Y 0.604167 0.894737
110 NAI 0.60396 0.907895
111 6V0 0.60396 0.896104
112 TXD 0.60396 0.907895
113 DND 0.60396 0.932432
114 NXX 0.60396 0.932432
115 NAX 0.60396 0.873418
116 ADP BMA 0.602151 0.918919
117 A2R 0.6 0.985915
118 OMR 0.598039 0.851852
119 TXE 0.598039 0.907895
120 XAH 0.597938 0.839506
121 7DT 0.593023 0.985714
122 AOC 0.592593 0.821918
123 4UV 0.591837 0.894737
124 DDS 0.590909 0.878378
125 139 0.590476 0.873418
126 CNA 0.584906 0.932432
127 6AD 0.58427 0.909091
128 5AS 0.583333 0.77907
129 5N5 0.581081 0.819444
130 GA7 0.58 0.906667
131 4UU 0.58 0.894737
132 4TC 0.576923 0.896104
133 ADJ 0.575472 0.851852
134 5CD 0.573333 0.805556
135 A4D 0.573333 0.819444
136 RGT 0.571429 0.958904
137 A3P 0.571429 0.971429
138 7D5 0.56962 0.878378
139 LAQ 0.568627 0.839506
140 F2R 0.564815 0.864198
141 80F 0.563636 0.841463
142 YLP 0.563107 0.819277
143 A A 0.5625 0.944444
144 UPA 0.561905 0.907895
145 AV2 0.56044 0.917808
146 COD 0.559633 0.811765
147 4UW 0.557692 0.860759
148 JB6 0.556701 0.883117
149 3AM 0.555556 0.929577
150 ATP A A A 0.555556 0.930556
151 A2P 0.552941 0.957143
152 TYM 0.552381 0.906667
153 NA7 0.552083 0.958904
154 EP4 0.551282 0.753247
155 MYR AMP 0.55102 0.817073
156 PPS 0.549451 0.873418
157 YLC 0.54717 0.839506
158 YLB 0.54717 0.819277
159 NAD 0.545455 0.931507
160 DAT 0.545455 0.905405
161 TYR AMP 0.544554 0.87013
162 G5A 0.544444 0.77907
163 M2T 0.544304 0.734177
164 DTA 0.544304 0.786667
165 3DH 0.54321 0.773333
166 128 0.542857 0.776471
167 AHZ 0.538462 0.817073
168 GTP 0.537634 0.92
169 SSA 0.537634 0.8
170 MTA 0.5375 0.773333
171 IOT 0.537037 0.831325
172 A3D 0.535714 0.918919
173 ARG AMP 0.533981 0.829268
174 7MD 0.533981 0.8625
175 AR6 AR6 0.533981 0.917808
176 YLA 0.53211 0.819277
177 AMP DBH 0.529412 0.893333
178 IMO 0.529412 0.929577
179 TAD 0.528846 0.884615
180 AYB 0.527273 0.809524
181 A5A 0.526882 0.807229
182 HDV 0.526882 0.893333
183 TSB 0.526316 0.819277
184 EAD 0.525424 0.873418
185 2AM 0.52439 0.943662
186 6RE 0.52381 0.759494
187 7DD 0.522727 0.985714
188 V3L 0.521739 0.971831
189 AVV 0.520833 0.896104
190 BTX 0.517857 0.841463
191 NAE 0.517241 0.894737
192 52H 0.515789 0.77907
193 54H 0.515789 0.788235
194 VMS 0.515789 0.788235
195 NSS 0.515464 0.8
196 BT5 0.513274 0.831325
197 NAQ 0.512821 0.871795
198 ZAS 0.511905 0.766234
199 J7C 0.511628 0.769231
200 A3N 0.511628 0.786667
201 5X8 0.511111 0.763158
202 53H 0.510417 0.77907
203 8X1 0.510417 0.752809
204 5CA 0.510417 0.8
205 NVA LMS 0.510204 0.752809
206 ARU 0.510204 0.860759
207 AF3 ADP 3PG 0.509259 0.8375
208 ZID 0.508475 0.918919
209 P1H 0.508197 0.851852
210 OVE 0.505882 0.905405
211 S4M 0.505747 0.666667
212 LEU LMS 0.50505 0.752809
213 LPA AMP 0.504673 0.817073
214 7MC 0.504587 0.841463
215 DZD 0.5 0.884615
216 FB0 0.5 0.804598
217 MAO 0.5 0.759036
218 DSZ 0.5 0.8
219 LSS 0.5 0.761364
220 DSH 0.5 0.725
221 P5A 0.5 0.744444
222 NDE 0.495935 0.932432
223 N0B 0.495798 0.819277
224 M24 0.495726 0.85
225 YLY 0.495726 0.809524
226 NJP 0.495575 0.945946
227 9K8 0.49505 0.714286
228 MGP 0.494737 0.884615
229 6C6 0.494624 0.881579
230 NAJ PZO 0.491379 0.848101
231 0WD 0.491228 0.921053
232 6G0 0.489583 0.884615
233 GJV 0.488636 0.75
234 6FA 0.488189 0.841463
235 5AD 0.486842 0.746479
236 KAA 0.485149 0.752809
237 GSU 0.485149 0.77907
238 71V 0.483146 0.907895
239 NEC 0.482759 0.746667
240 A3G 0.482759 0.8
241 ODP 0.482456 0.909091
242 FAS 0.48062 0.851852
243 FAD 0.48062 0.851852
244 7D7 0.480519 0.743243
245 FDA 0.480315 0.833333
246 N6P 0.48 0.915493
247 2SA 0.479167 0.932432
248 GP3 0.478723 0.921053
249 4TA 0.478261 0.807229
250 SFG 0.478261 0.75
251 G A A A 0.478261 0.871795
252 AMP NAD 0.478261 0.905405
253 NPW 0.477876 0.886076
254 NDP 0.477876 0.921053
255 NDC 0.47619 0.871795
256 YSA 0.47619 0.77907
257 NAJ PYZ 0.475 0.807229
258 MGO 0.474227 0.860759
259 GDP 0.473684 0.92
260 NZQ 0.473684 0.909091
261 TXP 0.473684 0.921053
262 6IA 0.473684 0.8375
263 A7D 0.472527 0.776316
264 SFD 0.469231 0.734043
265 A5D 0.468085 0.786667
266 SA8 0.468085 0.707317
267 ZDA 0.468085 0.864865
268 12D 0.46789 0.785714
269 PGS 0.467391 0.883117
270 MHZ 0.467391 0.697674
271 8PZ 0.466667 0.8
272 62F 0.466165 0.8625
273 DA 0.465909 0.878378
274 D5M 0.465909 0.878378
275 GGZ 0.464646 0.825
276 SAH 0.463158 0.74359
277 SAI 0.463158 0.734177
278 FAY 0.462687 0.8625
279 Y3J 0.4625 0.726027
280 PO4 PO4 A A A A PO4 0.460784 0.902778
281 AAM 0.460674 0.971429
282 RFL 0.459259 0.821429
283 SMM 0.459184 0.686047
284 HF7 0.459184 0.893333
285 AMZ 0.458824 0.916667
286 C2R 0.458824 0.90411
287 SAM 0.458333 0.690476
288 A3S 0.456522 0.810811
289 FNK 0.455224 0.804598
290 U A 0.453782 0.907895
291 7C5 0.453704 0.818182
292 EEM 0.453608 0.690476
293 AAT 0.453608 0.707317
294 XNP 0.452991 0.873418
295 A G 0.452991 0.883117
296 PRT 0.45283 0.931507
297 AIR 0.451219 0.901408
298 62X 0.45098 0.666667
299 DCA 0.45 0.823529
300 ETB 0.45 0.833333
301 GSP 0.45 0.873418
302 U A G G 0.449153 0.883117
303 NIA 0.448276 0.822785
304 A3T 0.446809 0.821918
305 A A A 0.446602 0.905405
306 K15 0.446602 0.682353
307 PUA 0.446281 0.884615
308 6K6 0.445545 0.930556
309 GEK 0.445545 0.7375
310 4YB 0.445455 0.761364
311 S7M 0.444444 0.690476
312 Z5A 0.443548 0.77907
313 1DG 0.443548 0.921053
314 DG1 0.443548 0.921053
315 0T1 0.442623 0.823529
316 COA 0.442623 0.823529
317 WSA 0.442478 0.788235
318 8BR 0.43956 0.906667
319 8Q2 0.438596 0.772727
320 101 0.438202 0.878378
321 IDP 0.4375 0.918919
322 NVA 2AD 0.4375 0.759494
323 9JJ 0.435714 0.8625
324 NAP 0.435484 0.945205
325 APU 0.434783 0.894737
326 A U 0.434783 0.87013
327 7RP 0.433333 0.928571
328 A6D 0.432692 0.722892
329 AMX 0.432 0.833333
330 J7V 0.432 0.833333
331 TAP 0.432 0.907895
332 COS 0.432 0.804598
333 CAO 0.432 0.795455
334 30N 0.432 0.752688
335 V1N 0.431193 0.917808
336 649 0.429825 0.744444
337 P5F 0.429577 0.823529
338 NA0 0.428571 0.932432
339 SCO 0.428571 0.823529
340 CMX 0.428571 0.823529
341 7RA 0.428571 0.957747
342 0UM 0.427184 0.698795
343 GAV 0.427184 0.884615
344 QQY 0.426966 0.815789
345 1RB 0.426966 0.885714
346 ACK 0.426966 0.861111
347 G1R 0.425743 0.907895
348 GCP 0.425743 0.896104
349 FAM 0.425197 0.804598
350 FCX 0.425197 0.795455
351 ACO 0.425197 0.795455
352 GNH 0.424242 0.907895
353 F2N 0.423611 0.813953
354 GKE 0.422018 0.884615
355 GDD 0.422018 0.884615
356 GDC 0.422018 0.884615
357 HAX 0.421875 0.804598
358 3AD 0.421687 0.805556
359 9GM 0.421569 0.896104
360 GNP 0.421569 0.896104
361 FA9 0.42069 0.864198
362 TM1 0.420561 0.77381
363 KB1 0.420561 0.698795
364 H6Y 0.42 0.945205
365 2MC 0.419847 0.769231
366 3KK 0.418605 0.804598
367 FYN 0.418605 0.823529
368 S8M 0.417476 0.759494
369 7L1 0.417323 0.795455
370 2VA 0.416667 0.8
371 26A 0.416667 0.763158
372 NHD 0.416667 0.905405
373 QQX 0.41573 0.805195
374 CA6 0.415385 0.729167
375 OXK 0.415385 0.804598
376 COK 0.415385 0.804598
377 SOP 0.415385 0.804598
378 MCD 0.415385 0.804598
379 YE1 0.413534 0.813953
380 RMB 0.413043 0.873239
381 FAI 0.413043 0.916667
382 AS 0.413043 0.833333
383 CO6 0.412214 0.804598
384 1VU 0.412214 0.795455
385 CMC 0.412214 0.804598
386 NMX 0.412214 0.76087
387 SXZ 0.411215 0.710843
388 ANZ 0.410714 0.8
389 SCA 0.410448 0.804598
390 CAJ 0.409091 0.804598
391 SCD 0.409091 0.823529
392 EO7 0.408602 0.788235
393 D3Y 0.407767 0.789474
394 CC5 0.407407 0.816901
395 KH3 0.40708 0.674419
396 A C A C 0.406504 0.848101
397 SLU 0.406504 0.770115
398 G 0.40625 0.906667
399 5GP 0.40625 0.906667
400 A1S 0.406015 0.804598
401 IVC 0.406015 0.813953
402 MLC 0.406015 0.804598
403 3HC 0.406015 0.813953
404 1HE 0.406015 0.786517
405 BCO 0.406015 0.804598
406 GTG 0.405405 0.886076
407 NMN AMP PO4 0.404959 0.87013
408 3D1 0.404762 0.773333
409 3L1 0.404762 0.773333
410 2BA 0.404255 0.915493
411 CMP 0.404255 0.901408
412 VRT 0.40404 0.769231
413 SO8 0.40404 0.789474
414 MCA 0.402985 0.795455
415 COO 0.402985 0.804598
416 CAA 0.402985 0.813953
417 3NZ 0.401869 0.782051
418 G2R 0.401869 0.884615
419 ZZB 0.4 0.77381
420 2FA 0.4 0.813333
421 MC4 0.4 0.76087
422 2CP 0.4 0.795455
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6B2M; Ligand: COA; Similar sites found with APoc: 146
This union binding pocket(no: 1) in the query (biounit: 6b2m.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 6GNO XDI None
2 1HBK COA None
3 4WG0 CHD None
4 5TVA AMP 1.25
5 5IFK HPA 1.3986
6 6FA4 D1W 1.7341
7 6EK3 OUL 1.80995
8 5EW9 5VC 1.84502
9 2HZL PYR 2.0979
10 6GSG RCO 2.0979
11 5FQK 6NT 2.23048
12 5A7Y SAH 2.44755
13 3G6K POP 2.44755
14 3G6K FAD 2.44755
15 6F5W KG1 2.44755
16 2OZ5 7XY 2.44755
17 4RZB NFQ 2.44755
18 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 2.45902
19 1SBR VIB 2.5
20 6F4W FMC 2.57511
21 6CS8 F9Y 2.7972
22 4F06 PHB 2.7972
23 3KLL MAL 2.7972
24 1GVF PGH 2.7972
25 2RC8 DSN 2.7972
26 4MCC 21X 2.84553
27 2UW1 GVM 2.95858
28 1D8C GLV 3.14685
29 1P7T PYR 3.14685
30 4Y7E BMA BMA BMA 3.14685
31 3TDC 0EU 3.14685
32 6BVI EC4 3.14685
33 6BVL EBY 3.14685
34 1TPY 16A 3.14685
35 5LX9 OLB 3.16901
36 5BSH PRO 3.2491
37 1CT9 AMP 3.4965
38 4HE2 AMP 3.4965
39 2P4S DIH 3.4965
40 4OUE IPT 3.4965
41 1RV1 IMZ 3.52941
42 4JAL SAH 3.59281
43 5LX6 78P 3.66492
44 2PZ8 APC 3.87324
45 1KQP ADJ 4.05904
46 4CNE SAH 4.11985
47 5NM7 GLY 4.13534
48 5FPE 3TR 4.1958
49 4RW3 PLM 4.1958
50 4UCC ZKW 4.29185
51 5TWJ SAM 4.32099
52 5FUI APY 4.54545
53 3ZF8 GDP 4.54545
54 5AWQ GLC GLC 4.54545
55 3KP6 SAL 4.63576
56 3RK1 ATP 4.64135
57 3RK0 AMP 4.64135
58 1WXI AMP 4.72727
59 5C1M OLC 4.8
60 2GWH PCI 4.8951
61 5N0O SAM 4.8951
62 6GEW SFG 4.8951
63 6GEW SAH 4.8951
64 3CV2 OXL 4.8951
65 1F9V ADP 4.8951
66 1EFV AMP 5.24476
67 1EFV FAD 5.24476
68 5FAG PPI 5.24476
69 5C9P FUC 5.24476
70 4KVL PLM 5.24476
71 5V3Y 5V8 5.24476
72 1KAH HIS 5.24476
73 2QCX PF1 5.32319
74 2OQ2 A3P 5.36398
75 5OJY CIT 5.90551
76 2WSI FAD 5.94406
77 2CIX CEJ 5.94406
78 1VMK GUN 6.13718
79 3SAO DBH 6.25
80 1K97 ASP 6.29371
81 1K97 CIR 6.29371
82 2JK0 ASP 6.29371
83 2BSA NAP 6.29371
84 2BSA FAD 6.29371
85 2D5Z L35 6.38298
86 5FJJ MAN 6.64336
87 4UHL VFV 6.99301
88 4MGA 27L 7.05882
89 5AAV GW5 7.14286
90 4O4Z N2O 7.14286
91 1FWV SGA MAG FUC 7.46269
92 1R6N 434 7.58294
93 1W8S FBP 7.60456
94 4WGF HX2 7.80488
95 3ESS 18N 7.82609
96 6EVN PRO PRO GLY PRO ALA GLY PRO PRO GLY 7.84314
97 5M36 9SZ 7.86026
98 5CHR 4NC 8.0292
99 2FJK 13P 8.04196
100 2AWN ADP 8.04196
101 1O97 AMP 8.39161
102 1O97 FAD 8.39161
103 4L80 OXL 8.39161
104 1G51 AMP 8.74126
105 3CH6 NAP 8.74126
106 3CH6 311 8.74126
107 5ZCO CHD 8.84354
108 5Z84 CHD 8.84354
109 5W97 CHD 8.84354
110 3E70 GDP 9.09091
111 5L1O 7PF 9.09091
112 4F4S EFO 9.21053
113 3LGS SAH 9.73783
114 1JGT APC 9.79021
115 1JGT CMA 9.79021
116 1O94 AMP 9.79021
117 3DLA NXX 9.79021
118 5E5U MLI 10.0503
119 1UUY PPI 10.1796
120 3FS1 ALA ALA LEU ALA ALA LEU LEU ALA ALA 10.4348
121 2WD7 VGD 10.4478
122 4WOE ADP 10.4895
123 1MJH ATP 10.4938
124 3K56 IS3 10.5263
125 1XNG ATP 10.8209
126 3BBH SFG 11.7073
127 1MXI SAH 11.875
128 5D63 FUC GLA GLA 11.8881
129 3FIU AMP 12.0482
130 3FIU POP 12.0482
131 5KJW 53C 12.2378
132 5W7B MYR 12.766
133 1KOR SIN 14.3357
134 1KOR ANP 14.3357
135 1KOR ARG 14.3357
136 2BOS GLA GAL GLC NBU 14.7059
137 2BOS GLA GAL GLC 14.7059
138 5Y02 HBX 15.8879
139 4YSX E23 15.9574
140 1Q19 APC 17.1329
141 1Q19 SSC 17.1329
142 1C4Q GLA GAL BGC 17.3913
143 2V5E SCR 18.5
144 2Y69 CHD 18.6047
145 4OGQ 7PH 21.6216
146 1GPM AMP 23.0769
Pocket No.: 2; Query (leader) PDB : 6B2M; Ligand: COA; Similar sites found with APoc: 46
This union binding pocket(no: 2) in the query (biounit: 6b2m.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1UO5 PIH None
2 3W54 RNB 1.3986
3 1FDJ 13P 1.3986
4 3ROE THM 1.50943
5 3OID TCL 1.93798
6 3BBD SAH 1.95122
7 1GEG GLC 1.95312
8 4CNG SAH 1.96078
9 3JU6 ANP 2.44755
10 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 2.7972
11 3SQP 3J8 2.7972
12 2HIM ASN 2.7972
13 2YBQ UP2 2.7972
14 4RUS NDG 2.94118
15 2XG5 EC5 3.46821
16 2XG5 EC2 3.46821
17 4G31 0WH 3.4965
18 4WHZ 3NL 3.4965
19 5YRV 5AD 3.64964
20 6ACS CIT 3.87597
21 5F7J ADE 4.1958
22 3NK7 SAM 4.33213
23 1MJT NAD 4.54545
24 5AWM ANP 4.54545
25 5H6S HDH 4.54545
26 6EMU SAM 4.56853
27 5H5F SAM 4.70085
28 5C1M 4VO 4.8
29 3R9C ECL 4.8951
30 2CDU ADP 4.8951
31 3AI3 SOE 4.94297
32 2BHW NEX 5.17241
33 2EAE FUL 5.24476
34 4CNK FAD 5.59441
35 3GYQ SAM 5.88235
36 4JCA CIT 7.18563
37 3COW 52H 7.30897
38 1ODJ GMP 8.51064
39 4TVD BGC 8.74126
40 3I7V ATP 9.70149
41 4XCP PLM 9.79021
42 3HW5 AMP 11.1111
43 3W5N RAM 12.5874
44 5AE2 FYC 13.2867
45 5AE2 FAD 13.2867
46 2BS5 BGC GAL FUC 13.3333
Pocket No.: 3; Query (leader) PDB : 6B2M; Ligand: COA; Similar sites found with APoc: 21
This union binding pocket(no: 3) in the query (biounit: 6b2m.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 5KGS 6SR 1.96937
2 2HHP FLC 2.0979
3 4A91 GLU 2.0979
4 1Q7E MET 2.7972
5 6I6X TLA 2.7972
6 5V49 MET 3.14685
7 5UGW GSH 3.42857
8 1LSH PLD 3.84615
9 5WJ6 B4A 3.84615
10 5WS9 ATP 3.84615
11 2W5P CL8 6.04027
12 1DTL BEP 6.21118
13 5HCN DAO 6.51341
14 1VHW ADN 6.71937
15 5ETJ IM5 7.69231
16 4DDY DN6 8.36502
17 4RF7 ARG 8.39161
18 5BOE PEP 8.39161
19 5ZCO PGV 8.84354
20 1M2Z BOG 14.0078
21 4OGQ 1O2 21.6216
Pocket No.: 4; Query (leader) PDB : 6B2M; Ligand: COA; Similar sites found with APoc: 11
This union binding pocket(no: 4) in the query (biounit: 6b2m.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 3G08 FEE 2.45614
2 4YJK URA 2.77778
3 4RL4 PPV 2.83019
4 6BVJ EAS 3.14685
5 2GN2 C5P 4.1958
6 2HJ9 AI2 4.1958
7 4XZ3 ACP 6.95652
8 2GZ3 NAP 6.99301
9 6CGN DA 8.74126
10 3KTA AP5 9.82659
11 2TOH HBI 10.1399
Pocket No.: 5; Query (leader) PDB : 6B2M; Ligand: COA; Similar sites found with APoc: 12
This union binding pocket(no: 5) in the query (biounit: 6b2m.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 1DL2 NAG NAG BMA 2.44755
2 2RCA GLY 2.44755
3 2XI7 XI7 2.71739
4 5VW2 NAP 2.7972
5 5VW2 FDA 2.7972
6 1IIM TTP 2.7972
7 4KQL 1SG 3.84615
8 3HCH RSM 6.16438
9 1NC2 DOE 6.97674
10 5AWV GHP 3MY 3FG GHP GHP OMY 3FG NAG MAN 8.39161
11 1ELI PYC 8.74126
12 2ZFZ ARG 15.1899
Pocket No.: 6; Query (leader) PDB : 6B2M; Ligand: COA; Similar sites found with APoc: 12
This union binding pocket(no: 6) in the query (biounit: 6b2m.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 5MM0 GDD 1.74825
2 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 4.1841
3 5J5R 6G1 4.8951
4 5J5R IMP 4.8951
5 2CIG 1DG 5.03145
6 3MAN BMA BMA MAN 5.24476
7 4BVA NDP 5.59441
8 1T27 PCW 6.27306
9 5EEH P9P 6.99301
10 6BQC LOP 8.04196
11 3G5D 1N1 11.8881
12 2Y91 98J 21.5094
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