Receptor
PDB id Resolution Class Description Source Keywords
5TWO 1.93 Å NON-ENZYME: SIGNAL_HORMONE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGAND BIND IN COMPLEX WITH A NOVEL SELECTIVELY PPAR GAMMA-MODULATING L5 1 HOMO SAPIENS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGNAD BINDOMAIN SELECTIVE PPAR GAMMA LIGAND VSP-51 DNA BINDING PRTRANSCRIPTION
Ref.: IDENTIFICATION OF A NOVEL SELECTIVE PPAR GAMMA LIGA UNIQUE BINDING MODE AND IMPROVED THERAPEUTIC PROFIL VITRO. SCI REP V. 7 41487 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
7MV A:501;
Valid;
none;
submit data
392.853 C23 H18 Cl F N2 O c1ccc...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5TWO 1.93 Å NON-ENZYME: SIGNAL_HORMONE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGAND BIND IN COMPLEX WITH A NOVEL SELECTIVELY PPAR GAMMA-MODULATING L5 1 HOMO SAPIENS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGNAD BINDOMAIN SELECTIVE PPAR GAMMA LIGAND VSP-51 DNA BINDING PRTRANSCRIPTION
Ref.: IDENTIFICATION OF A NOVEL SELECTIVE PPAR GAMMA LIGA UNIQUE BINDING MODE AND IMPROVED THERAPEUTIC PROFIL VITRO. SCI REP V. 7 41487 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 5TWO - 7MV C23 H18 Cl F N2 O c1ccc(cc1)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 5TWO - 7MV C23 H18 Cl F N2 O c1ccc(cc1)....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 5TWO - 7MV C23 H18 Cl F N2 O c1ccc(cc1)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 7MV; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 7MV 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5TWO; Ligand: 7MV; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5two.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
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