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Receptor
PDB id Resolution Class Description Source Keywords
5THZ 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF CURJ CARBON METHYLTRANSFERASE MOOREA PRODUCENS 3L METHYLTRANSFERASE TRANSFERASE LYASE
Ref.: DOMAIN ORGANIZATION AND ACTIVE SITE ARCHITECTURE OF POLYKETIDE SYNTHASE C-METHYLTRANSFERASE. ACS CHEM. BIOL. V. 11 3319 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH B:501;
A:501;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
FLC A:502;
Invalid;
none;
submit data
189.1 C6 H5 O7 C(C(=...
GOL B:502;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5THZ 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF CURJ CARBON METHYLTRANSFERASE MOOREA PRODUCENS 3L METHYLTRANSFERASE TRANSFERASE LYASE
Ref.: DOMAIN ORGANIZATION AND ACTIVE SITE ARCHITECTURE OF POLYKETIDE SYNTHASE C-METHYLTRANSFERASE. ACS CHEM. BIOL. V. 11 3319 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5THZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5THZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5THZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5THZ; Ligand: SAH; Similar sites found with APoc: 747
This union binding pocket(no: 1) in the query (biounit: 5thz.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 1LSS NAD None
2 3CH6 311 1.04895
3 3CH6 NAP 1.04895
4 4FC7 NAP 1.08303
5 4FC7 COA 1.08303
6 1BXK NAD 1.12676
7 2UVO NAG 1.16959
8 2UVO NDG 1.16959
9 5HSA FAS 1.23457
10 1RRC ADP 1.3289
11 1WMA AB3 1.44928
12 1WMA NDP 1.44928
13 6ER9 FAD 1.48148
14 6ER9 NAP 1.48148
15 3CGB FAD 1.48148
16 2VVL FAD 1.48148
17 4MIG G3F 1.48148
18 4M00 SUC 1.48148
19 4K5S PM0 1.48148
20 4K5S FAD 1.48148
21 2GK6 ADP 1.48148
22 3X27 TRP 1.49254
23 3LZW FAD 1.50602
24 5Z75 NAD 1.52905
25 2EJU SAH 1.5873
26 2YY7 NAD 1.60256
27 2JAP NDP 1.61943
28 4MO2 FDA 1.63043
29 4MO2 FAD 1.63043
30 1EDO NAP 1.63934
31 2WPB ZZI 1.64474
32 4BWL MN9 1.64474
33 5E1M SAH 1.65975
34 5E1M PRO PRO LYS ARG ILE ALA 1.65975
35 3O03 NAP 1.71821
36 5KOX FAD 1.7284
37 5KOX RFP 1.7284
38 5GT9 NAP 1.7284
39 4XQC NAD 1.7284
40 5NMX FAD 1.7284
41 5NMX NAP 1.7284
42 1DJN ADP 1.7284
43 5ZXD ATP 1.7284
44 5X68 FAD 1.79028
45 3KLJ FAD 1.81818
46 4ITU NAI 1.85874
47 4ITU 1HS 1.85874
48 5ZBR ANP 1.86667
49 5DT6 GLU 1.87266
50 2A14 SAH 1.90114
51 3ABI NAD 1.91781
52 2ZAT NAP 1.92308
53 1E5Q NDP 1.97531
54 5FJN BE2 1.97531
55 5FJN FAD 1.97531
56 3NTA FAD 1.97531
57 2QA1 FAD 1.97531
58 2FR1 NDP 1.97531
59 4TQK NAG 1.97531
60 2RAB FAD 1.97531
61 2CUN 3PG 1.97531
62 2RAB NAD 1.97531
63 4FWE FAD 1.97531
64 1X87 NAD 1.97531
65 4NBU NAI 2
66 4YAC NAI 2.0202
67 2GN4 NDP 2.03488
68 2GN4 UD1 2.03488
69 3O7W SAM 2.04082
70 6B92 SAH 2.04082
71 2BD0 NAP 2.04918
72 1YQZ FAD 2.05479
73 1SQL GUN 2.05479
74 1VL0 NAI 2.05479
75 5FEU NAP 2.06186
76 3BP1 GUN 2.06897
77 3ITJ FAD 2.07101
78 5LOG SAH 2.14592
79 2Q7V FAD 2.15385
80 2BGM NAJ 2.15827
81 5GWT NAD 2.15827
82 5GWT SIN 2.15827
83 1BDB NAD 2.16606
84 5DF1 NAP 2.17391
85 5DF1 58X 2.17391
86 5K4W NAI 2.18069
87 5K4W THR 2.18069
88 3CTY FAD 2.19436
89 4MOP 2H5 2.22222
90 1NAA 6FA 2.22222
91 5VN0 FAD 2.22222
92 5VN0 NAI 2.22222
93 2NPX FAD 2.22222
94 2NPX NAD 2.22222
95 2RGO FAD 2.22222
96 2EB5 OXL 2.24719
97 1ELI PYC 2.31362
98 5FFF NAP 2.33463
99 5FFF 5XC 2.33463
100 3GD4 FAD 2.34834
101 3GD4 NAD 2.34834
102 1XHL NDP 2.3569
103 4L9Z OXL 2.35988
104 3FRH SAH 2.37154
105 5FUB SAH 2.37389
106 1R6D DAU 2.37389
107 1R6D NAD 2.37389
108 6GFK SAH 2.39044
109 4X9M FAD 2.39234
110 4HSU FAD 2.41935
111 4GUS FAD 2.41935
112 1T3D CYS 2.42215
113 3NUG NAD 2.42915
114 5YJI 8WO 2.46914
115 5YJI SAH 2.46914
116 4N49 SAM 2.46914
117 2JJQ SAH 2.46914
118 5G3U FDA 2.46914
119 5G3U ITW 2.46914
120 2BHZ MAL 2.46914
121 3GDN FAD 2.46914
122 3GDN HBX 2.46914
123 4DSG FAD 2.46914
124 4DSG UDP 2.46914
125 2E5V FAD 2.46914
126 1PS9 FAD 2.46914
127 5ZBC FAD 2.46914
128 2DKH 3HB 2.46914
129 2DKH FAD 2.46914
130 3NYC FAD 2.46914
131 3NYC IAR 2.46914
132 1YQT ADP 2.46914
133 5YB7 FAD 2.46914
134 3V1U NAD 2.46914
135 5YB7 ORN 2.46914
136 4D42 NAP 2.48227
137 4D42 W0I 2.48227
138 1F3L SAH 2.49221
139 2Y6Q FAD 2.51256
140 2Y6Q I7T 2.51256
141 5L4S 6KX 2.51572
142 5L4S NAP 2.51572
143 1W6F ISZ 2.51799
144 3HDY GDU 2.51889
145 3HDY FDA 2.51889
146 3HDY FAD 2.51889
147 4UP3 FAD 2.54777
148 4UP3 NDP 2.54777
149 3VC1 SAH 2.5641
150 3VC1 GST 2.5641
151 3O26 NDP 2.57235
152 5M58 SAH 2.6087
153 1XX6 ADP 2.6178
154 3RKR NAP 2.67176
155 4UCI SAM 2.71605
156 5JJR SAH 2.71605
157 3CGD FAD 2.71605
158 3CGD COA 2.71605
159 3UOY NAP 2.71605
160 3UOY FAD 2.71605
161 1QO8 FAD 2.71605
162 4YKG FAD 2.71605
163 1RSG FAD 2.71605
164 2WHX ADP 2.71605
165 3CGD NAD 2.71605
166 5BUK FAD 2.71605
167 4Z24 FAD 2.71605
168 5WGR FAD 2.71605
169 2WPF FAD 2.71605
170 2WPF WPF 2.71605
171 4IEE AGS 2.71605
172 1BZL FAD 2.71605
173 5GSN NAP 2.71605
174 5GSN FAD 2.71605
175 4D7E FAD 2.71605
176 3H8V ATP 2.73973
177 3I7S PYR 2.73973
178 1BG2 ADP 2.76923
179 4ONQ SFG 2.80112
180 3G89 SAM 2.81124
181 5T2U NAP 2.82258
182 4E70 N7I 2.83505
183 1T5C ADP 2.86533
184 1UAY ADN 2.89256
185 5YU3 NAD 2.90698
186 5YU3 PRO 2.90698
187 5U19 827 2.93255
188 5U19 SAH 2.93255
189 1XF1 CIT 2.96296
190 1KNR FAD 2.96296
191 1Q19 SSC 2.96296
192 1A0J BEN 2.96296
193 2HQM FAD 2.96296
194 1PN0 FAD 2.96296
195 1PN0 IPH 2.96296
196 4JJJ CBI 2.96296
197 5F2K SAH 2.98913
198 5F2K OCA 2.98913
199 2Q28 ADP 3.01418
200 2BZG SAH 3.01724
201 3P9C SAH 3.02198
202 4FRZ ADP 3.10881
203 5JGL SAM 3.11419
204 4OHU 2TK 3.11419
205 4OHU NAD 3.11419
206 4RDH AMP 3.125
207 1FP2 SAH 3.125
208 4RDI ATP 3.125
209 1LDN FBP 3.16456
210 1EFV FAD 3.1746
211 4C4A SAH 3.17919
212 4M37 SAH 3.207
213 3QOX SAH 3.20988
214 3M6W SAM 3.20988
215 4RSL FAD 3.20988
216 5BRT CH9 3.20988
217 5BRT FAD 3.20988
218 1Q1R FAD 3.20988
219 4URF NAD 3.22581
220 4J1Q NDP 3.23276
221 1VMK GUN 3.2491
222 4D79 ATP 3.26087
223 4GKV NAD 3.27381
224 5THQ NDP 3.30882
225 1V35 NAI 3.34347
226 2REG CHT 3.3557
227 2GDZ NAD 3.37079
228 1WY7 SAH 3.38164
229 5DLY 5D7 3.38346
230 5DLY SAH 3.38346
231 3LKZ SFG 3.42679
232 1QK3 5GP 3.43348
233 6GAR FAD 3.4384
234 3S1S SAH 3.45679
235 4RVG SAM 3.45679
236 4RVG TYD 3.45679
237 1D4D FAD 3.45679
238 4HA6 FAD 3.45679
239 5I39 FAD 3.45679
240 3ICT FAD 3.45679
241 3ICR FAD 3.45679
242 3ICS FAD 3.45679
243 3LAD FAD 3.45679
244 3AB1 FAD 3.45679
245 3ICS ADP 3.45679
246 1GET FAD 3.45679
247 1GET NAP 3.45679
248 4YAG NAI 3.46021
249 1G60 SAM 3.46154
250 2W58 ADP 3.46535
251 5W7M SAH 3.52564
252 1I8T FAD 3.54223
253 4GLL NAD 3.56083
254 1XKQ NDP 3.57143
255 4CNK FAD 3.58056
256 2F5Z FAD 3.5865
257 5YF1 8V0 3.59116
258 5YF1 SFG 3.59116
259 3F4F UMP 3.59281
260 3EVF SAH 3.61011
261 3EVF GTA 3.61011
262 3I53 SAH 3.61446
263 5K0A FAD 3.63636
264 4O0L NDP 3.63636
265 4KIB SAH 3.64146
266 4CVN ADP 3.64964
267 3ELW SAM 3.66667
268 3ELW GP3 3.66667
269 1PR9 NAP 3.68852
270 3D3W NAP 3.68852
271 3QWI CUE 3.7037
272 3QWI NAP 3.7037
273 2C7G FAD 3.7037
274 2C7G ODP 3.7037
275 3COB ADP 3.7037
276 2VVM FAD 3.7037
277 5TTJ FAD 3.7037
278 3NTD FAD 3.7037
279 3S5W FAD 3.7037
280 4A59 AMP 3.7037
281 3PIJ FRU 3.7037
282 2NCD ADP 3.7037
283 1TZD ADP 3.7037
284 5YEC ATP 3.7037
285 5JWC FAD 3.7037
286 2ZJ1 ARJ 3.7037
287 2ZJ1 NAD 3.7037
288 1BC5 SAH 3.71747
289 2VT3 ATP 3.72093
290 2PEL LBT 3.81356
291 1ZEM NAD 3.81679
292 3LCC SAH 3.82979
293 5WUW NAP 3.83275
294 1RJW ETF 3.83481
295 1JJ7 ADP 3.84615
296 4M73 M72 3.85757
297 4M73 SAH 3.85757
298 1NV8 SAM 3.87324
299 1NV8 MEQ 3.87324
300 5JCA FAD 3.87324
301 5GLT BGC GAL NAG GAL 3.87324
302 4USQ FAD 3.87812
303 3CBG SAH 3.87931
304 5EJ2 NAD 3.8961
305 2OG2 MLI 3.89972
306 3FSY SCA 3.91566
307 4O48 ASP 3.91566
308 5XFI NAG NAG BMA MAN MAN NAG GAL NAG 3.92157
309 6EL3 NAP 3.93701
310 2ZWA SAH 3.95062
311 5T67 JHZ 3.95062
312 5T67 SAH 3.95062
313 5X62 SAH 3.95062
314 5ZYN FAD 3.95062
315 5MZI FYK 3.95062
316 5MZI FAD 3.95062
317 1YY5 FAD 3.95062
318 4TXI FAD 3.95062
319 5Y77 FAD 3.95062
320 5KVA SAM 3.95683
321 3HB5 NAP 3.97554
322 5MB4 NAG 3.99003
323 5MB4 NDG 3.99003
324 3LST SAH 4.02299
325 5E72 SAM 4.04624
326 1IXI 2HP 4.04984
327 5J60 FAD 4.0625
328 2VDV SAM 4.06504
329 4AG5 ADP 4.08163
330 2PX8 SAH 4.08922
331 5ULP KB1 4.10448
332 2OEM 1AE 4.11622
333 5CUQ NSC 4.11985
334 5DM1 SAH 4.11985
335 5DM1 5D7 4.11985
336 3MQ2 SAH 4.12844
337 4WZ6 ATP 4.13793
338 2HMT NAI 4.16667
339 1O94 ADP 4.16667
340 1N5D NDP 4.16667
341 2HNK SAH 4.1841
342 1RJD SAM 4.19162
343 4C3Y FAD 4.19753
344 2IVD FAD 4.19753
345 2V6G NAP 4.19753
346 4AP3 FAD 4.19753
347 4AP3 NAP 4.19753
348 5MLR NAP 4.19753
349 5MLR GRQ 4.19753
350 4C3Y ANB 4.19753
351 5OC1 FAD 4.19753
352 3LXD FAD 4.19753
353 5J5Z FAD 4.19753
354 1H9A NAP 4.19753
355 6H3O FAD 4.19753
356 5YJF 8WO 4.22535
357 5YJF SAH 4.22535
358 1TL2 NDG 4.23729
359 4Y9D NAI 4.2623
360 4NBW NAD 4.28016
361 2VVG ADP 4.28571
362 2JB2 FAD 4.29448
363 2JB2 PHE 4.29448
364 1XG5 NAP 4.30108
365 2XT3 ADP 4.36047
366 2FWP CIT 4.37158
367 1I1N SAH 4.42478
368 3NDJ SAH 4.44444
369 3NDJ JHZ 4.44444
370 6B3A SAM 4.44444
371 4LHD GLY 4.44444
372 5C9P FUC 4.44444
373 1REO FAD 4.44444
374 1ZK7 FAD 4.44444
375 3NKS FAD 4.44444
376 4O1M NAD 4.44444
377 1RYI GOA 4.45026
378 1RYI FAD 4.45026
379 4MCC 21X 4.47154
380 3LA3 2FT 4.52675
381 5Z2F PDC 4.5283
382 4OM8 NAD 4.53074
383 5UFN SAH 4.62185
384 3LCV SAM 4.62633
385 4TTQ ATP 4.65116
386 3AFN NAP 4.65116
387 1KYZ SAH 4.65753
388 1KYZ FER 4.65753
389 3HVJ 705 4.69136
390 1GTE FAD 4.69136
391 1LVL NAD 4.69136
392 5GVR LMR 4.70085
393 1NW5 SAM 4.70219
394 1FUT 2GP 4.71698
395 1DL5 SAH 4.73186
396 2AOT SAH 4.79452
397 1JQD SAH 4.79452
398 1JQD HSM 4.79452
399 1NNU TCT 4.80349
400 1NNU NAD 4.80349
401 3TKY SAH 4.8913
402 1IM8 SAI 4.91803
403 3X0D SAH 4.93827
404 4X60 3XV 4.93827
405 4X60 SFG 4.93827
406 2IZ1 ATR 4.93827
407 1ZGA SAH 4.93827
408 3E1T FAD 4.93827
409 1COY FAD 4.93827
410 1UWK NAD 4.93827
411 1UWK URO 4.93827
412 1NFQ NAI 4.93827
413 1O5O U5P 4.97738
414 2AWN ADP 4.98688
415 6CI9 NAP 5.01931
416 3BXO SAM 5.02092
417 2WA2 SAM 5.07246
418 2HK9 ATR 5.09091
419 5ICE SAH 5.11364
420 5ICE 2H4 5.11364
421 1XTP SAI 5.11811
422 1I0B PEL 5.12048
423 3TKA SAM 5.18518
424 6F7L FAD 5.18518
425 2CDU ADP 5.18518
426 2CDU FAD 5.18518
427 2YG3 FAD 5.18518
428 1Y8Q ATP 5.20231
429 2EWM NAD 5.22088
430 5ERG SAM 5.22193
431 3RFV 15L 5.24345
432 3RFV NAI 5.24345
433 1WG8 SAM 5.26316
434 4RPL FAD 5.26316
435 4RPL 3UC 5.26316
436 1H5Q NAP 5.28302
437 2AG5 NAD 5.28455
438 5ZZ6 ADP 5.28846
439 1QAN SAH 5.32787
440 2FK8 SAM 5.34591
441 5JBX MLI 5.36398
442 3GRU AMP 5.42373
443 2PWY SAH 5.42636
444 1H82 GZZ 5.4321
445 1H82 FAD 5.4321
446 5TSH ADP 5.4321
447 4JDR FAD 5.4321
448 2PK3 A2R 5.4321
449 5IFK HPA 5.44872
450 3OU2 SAH 5.50459
451 3SJ7 NDP 5.55556
452 2F6U CIT 5.55556
453 1XXR MAN 5.59006
454 1XDS SAM 5.61497
455 6APL C5P 5.61497
456 1O5I NAD 5.62249
457 2DPM SAM 5.6338
458 1G0N PHH 5.65371
459 1G0N NDP 5.65371
460 5JE0 AZ8 5.66802
461 5JE0 SAH 5.66802
462 3GEG NAD 5.66802
463 3A4V NAD 5.67823
464 3A4V PYR 5.67823
465 5O98 NAP 5.67823
466 6E1Q CFA 5.67901
467 2RH4 EMO 5.67901
468 2IID FAD 5.67901
469 2IID PHE 5.67901
470 6GAS FAD 5.67901
471 6ECU SAH 5.6962
472 4Q9N NAI 5.7047
473 3LTW HLZ 5.71429
474 1L3I SAH 5.72917
475 2XOC ADE 5.74713
476 1F9V ADP 5.76369
477 5TWB FAD 5.81395
478 1JJV ATP 5.82524
479 1JA9 NDP 5.83942
480 4FZV SAM 5.85774
481 2WSB NAD 5.90551
482 3H2B SAH 5.91133
483 1E1M NAP 5.92593
484 1E1M FAD 5.92593
485 4NBT NAD 5.92593
486 3DZ6 M8E 5.97015
487 4URG C2E 5.98802
488 2EFJ SAH 5.98958
489 3FZG SAM 6
490 1LVG ADP 6.06061
491 6C8R EQV 6.0686
492 6C8R SAH 6.0686
493 3UCL NAP 6.17284
494 3UCL CYH 6.17284
495 3UCL FAD 6.17284
496 1GPE FAD 6.17284
497 4YRY NAD 6.17284
498 4U8P UDP 6.17284
499 4U8P FDA 6.17284
500 4JLS 3ZE 6.17284
501 4YRY FAD 6.17284
502 1U1J MET 6.17284
503 3MAG SAH 6.18893
504 1GOJ ADP 6.19718
505 3P2E SAH 6.22222
506 3MCT SAH 6.39731
507 1D7O NAD 6.39731
508 1D7O TCL 6.39731
509 5BSZ SAH 6.4
510 3AD8 FAD 6.40394
511 3AD8 PYC 6.40394
512 3AD8 NAD 6.40394
513 5TS5 FAD 6.40496
514 3GF4 FAD 6.41026
515 3GF4 UPG 6.41026
516 4KRG SAH 6.41975
517 5MW4 5JU 6.41975
518 5L2R MLA 6.41975
519 2JAH NDP 6.47773
520 5Z2L NDP 6.53061
521 2PD4 DCN 6.54545
522 2PD4 NAD 6.54545
523 5K7U SAM 6.59026
524 3PT9 SAH 6.66667
525 5BVA FAD 6.66667
526 3A28 NAD 6.66667
527 3DUW SAH 6.72646
528 2XKO AKG 6.74157
529 4LWP SAH 6.79348
530 4TQG NDP 6.81115
531 4Y30 49L 6.83761
532 4Y30 SAH 6.83761
533 5FWA J7C 6.91358
534 1V59 NAD 6.91358
535 4J36 FAD 6.91358
536 4J36 1HR 6.91358
537 1V59 FAD 6.91358
538 1Q0S SAH 6.94981
539 2BES RES 6.97674
540 5IL1 SAM 7
541 1VL8 NAP 7.11611
542 1I9G SAM 7.14286
543 2Y65 ADP 7.16049
544 3OJF NDP 7.16049
545 3OJF IMJ 7.16049
546 1GZ6 NAI 7.21003
547 3TLJ SAH 7.23861
548 3WMX NAD 7.26257
549 3WMX THR 7.26257
550 5XNC MTA 7.27763
551 4XUC 43G 7.33945
552 4XUC SAM 7.33945
553 4BQS ADP 7.38636
554 6F97 FAD 7.40741
555 5XLX SAH 7.44681
556 6ECT SAM 7.47664
557 4NEC SAH 7.57576
558 1YXM ADE 7.59076
559 3QJ4 FAD 7.60234
560 4NTD FAD 7.64706
561 2NXE SAM 7.65432
562 3X0V FAD 7.65432
563 3AXB FAD 7.65432
564 3AXB PRO 7.65432
565 5CG1 NAD BBN 7.65432
566 4CQM NAP 7.66284
567 1MID LAP 7.69231
568 2RGJ FAD 7.71144
569 1ZQ9 SAM 7.7193
570 2ZIF SAM 7.74411
571 3OID NDP 7.75194
572 6FDF SAH 7.78443
573 2EG5 SAH 7.7957
574 2Q1W NAD 7.80781
575 1GEG NAD 7.8125
576 3WSG CIT 7.93651
577 5ZW3 SAH 8
578 3C3Y SAH 8.01688
579 2GAG FAD 8.09524
580 2GAG NAD 8.09524
581 2GAG FOA 8.09524
582 5GWX SAR 8.09859
583 5GWX SAM 8.09859
584 3C6K SPD 8.13648
585 3C6K MTA 8.13648
586 5DX8 SFG 8.14815
587 6ARJ BW4 8.14815
588 5DXA SFG 8.14815
589 5DX0 SFG 8.14815
590 6ARJ SAH 8.14815
591 5DX1 SFG 8.14815
592 5DWQ SFG 8.14815
593 3GCZ SAM 8.15603
594 1G55 SAH 8.16327
595 1TJY PAV 8.22785
596 3KIH GDL 8.24742
597 3GDH SAH 8.29876
598 2OBF SAH 8.3045
599 2OBF F83 8.3045
600 5E9W SAH 8.33333
601 2DTX BMA 8.33333
602 5L53 NAP 8.33333
603 1EK6 UPG 8.33333
604 1EK6 NAI 8.33333
605 1KPH SAH 8.36237
606 3PFG TLO 8.36502
607 3PFG SAM 8.36502
608 2ZFU SAH 8.37209
609 5ME4 HP4 8.39416
610 1XHC FAD 8.44687
611 1Q7B NAP 8.60656
612 1IY8 NAD 8.61423
613 3RNM FAD 8.62069
614 1U2Z SAH 8.64198
615 1DCP HBI 8.65385
616 1M0S CIT 8.6758
617 2XYQ SAH 9.01639
618 3BGD SAH 9.1358
619 3BGD PM6 9.1358
620 1N2X SAM 9.30233
621 5FA8 SAM 9.31677
622 1L1E SAH 9.40767
623 3KIF GDL 9.43396
624 2P41 SAH 9.5082
625 4II2 ATP 9.63855
626 4J4H NAI 9.65251
627 4J4H 1J1 9.65251
628 6BQ6 TER 9.66767
629 3EGI ADP 9.70874
630 5OVK NDP 9.76562
631 1C3V PDC 9.79592
632 2CH5 NAG 9.79827
633 2CH5 NDG 9.79827
634 1SQF SAM 9.87654
635 4ZCC FAD 9.87654
636 4ZCC NAI 9.87654
637 3THR C2F 9.89761
638 2DT5 NAD 9.95261
639 1UZN NAP 10.1215
640 4FN4 NAD 10.1235
641 5DNK SAH 10.1235
642 3A4T SFG 10.219
643 1KYQ NAD 10.219
644 2QZ4 ADP 10.3053
645 5HJM MTA 10.5114
646 3EVG SAH 10.5455
647 5FTW SAH 10.5469
648 4QTU SAM 10.5769
649 3SSO SAH 10.6173
650 2R4J FAD 10.6173
651 2R4J 13P 10.6173
652 4YMH SAH 10.8333
653 2O07 SPD 10.8553
654 2O07 MTA 10.8553
655 5BW4 SAM 10.8614
656 1R18 SAH 10.8642
657 1LK7 DER 10.917
658 1E6E FAD 10.9375
659 3DXY SAM 11.0092
660 1JQ3 AAT 11.1486
661 3RJ5 NAD 11.4173
662 4POO SAM 11.5
663 2AE2 PTO 11.5385
664 2AE2 NAP 11.5385
665 3QVP FAD 11.6049
666 5O42 NAD 11.6788
667 5O42 9JW 11.6788
668 5O42 BGC 11.6788
669 4BLW AMP 11.7647
670 4BLW SAH 11.7647
671 2HXW FLC 11.8143
672 1QG6 NAD 11.8774
673 1QG6 TCL 11.8774
674 6HKE LMR 11.9497
675 6HKE MLT 11.9497
676 5GM1 SAH 12.0988
677 5F8F SFG 12.2016
678 4DCM SAM 12.2667
679 1O8B ABF 12.3288
680 1G6H ADP 12.4514
681 4A6D SAM 12.4646
682 1P77 ATR 12.5
683 5L95 AMP 12.5
684 1FL2 FAD 12.5806
685 1AE1 NAP 12.8205
686 5KOK S9T 12.8463
687 5KOK SAH 12.8463
688 5KOK R9T 12.8463
689 6C5B SAH 13.1965
690 3FUU ADN 13.2841
691 3DMH GMP 13.3333
692 3DMH SAM 13.3333
693 3H4S ADP 13.3333
694 4U00 ADP 13.5246
695 1FK8 NAD 13.6187
696 1ZBQ NAD 13.7615
697 5N5D SAM 14.1593
698 6GKV SAH 14.245
699 6ECW SAH 14.2857
700 4OBW SAM 14.3969
701 5MGZ SAH 14.8305
702 3SJU NDP 15.0538
703 4PIO SAH 15.1703
704 4PIO AVI 15.1703
705 3TN7 NJP 15.1751
706 4IWN GEK 15.8025
707 2PT9 2MH 15.8879
708 2PT9 S4M 15.8879
709 3T7S SAM 16.0448
710 2BOS GLA GAL GLC NBU 16.1765
711 2BOS GLA GAL GLC 16.1765
712 1FP1 SAH 16.5432
713 3BFV ADP 16.6052
714 1QZZ SAM 16.7901
715 5Y02 MXN 16.8224
716 4YSX FAD 17.3077
717 5WLB GNP 17.6471
718 4KRI SAH 17.7778
719 1Z3C SA8 17.7852
720 1JG3 ADN 17.8723
721 2I7C AAT 18.3746
722 5EEH P9P 18.617
723 5EEH SAH 18.617
724 1KPG SAH 18.8153
725 4YUW 4JU 19.0789
726 4YUW S4M 19.0789
727 4PNE SAH 19.2053
728 2KIN ADP 20
729 5E8J SAH 20.4545
730 6DUB SAH 20.7207
731 4GQB 0XU 22.7273
732 3MB5 SAM 23.1373
733 3GU3 SAH 23.2394
734 4M38 SAH 23.8095
735 1XCL SAH 23.8298
736 5WP4 SAH 24.1975
737 5WP5 SAH 24.1975
738 3OFK SAH 24.537
739 6F5Z SAH 24.5902
740 5FA5 MTA 25
741 1EJ0 SAM 27.2222
742 1P1C SAH 28.1407
743 1TPY SAH 29.2683
744 4R6W PC 29.845
745 4R6W SAH 29.845
746 5MPT SAH 44.1975
747 6D6Y SAH 49.1358
Pocket No.: 2; Query (leader) PDB : 5THZ; Ligand: SAH; Similar sites found with APoc: 83
This union binding pocket(no: 2) in the query (biounit: 5thz.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 5OCQ CIT 1.05263
2 1WD4 AHR 1.23457
3 4IV9 FAD 1.7284
4 3K7M FAD 1.7284
5 5MZN ADP 1.7284
6 5Y1G NAD 1.82927
7 5Y1G AKB 1.82927
8 3ITJ CIT 2.07101
9 1NAA ABL 2.22222
10 1U7T TDT 2.29885
11 4BV6 FAD 2.43408
12 5J7X FAD 2.71605
13 4YKG NAD 2.71605
14 5EOW FAD 2.71605
15 4EUE NAI 2.71605
16 1H8P PC 2.75229
17 2CFC NAD 2.8
18 4UP4 GAL NAG 2.96296
19 2XVF FAD 2.96296
20 2XVE FAD 2.96296
21 2WYV NAD 3.06513
22 3H4V NAP 3.125
23 3H4V DVP 3.125
24 1FP2 HMO 3.125
25 1EFV AMP 3.1746
26 4D04 FAD 3.20988
27 4D04 NAP 3.20988
28 3OIG NAD 3.38346
29 3AYI HCI 3.45679
30 3AYI FAD 3.45679
31 1G6O ADP 3.7037
32 3NT6 FAD 3.7037
33 4PX9 ADP 3.76712
34 2ZFI ADP 3.82514
35 3A4M ADP 3.84615
36 5JCA NDP 3.87324
37 2CUL FAD 3.87931
38 2CE7 ADP 3.95062
39 1A27 NAP 4.49827
40 1GEE NAD 4.5977
41 5WQP NAP 4.70085
42 5WQP NCA 4.70085
43 1COY AND 4.93827
44 5MIT NAP 5.19878
45 5MIT FAD 5.19878
46 3NHB ADP 5.22876
47 1GXU 2HP 5.49451
48 1VHT BA3 5.50459
49 3JQF NAP 5.55556
50 5K6A NAP 5.55556
51 4CME NAP 5.55556
52 3BMQ NAP 5.55556
53 3JQ9 NAP 5.55556
54 4CM4 NAP 5.55556
55 4CM9 NAP 5.55556
56 5BWD FUM 5.67901
57 4B63 NAP 5.67901
58 4B63 FAD 5.67901
59 4B63 ORN 5.67901
60 4WOP CTP 5.77778
61 1KOL NAD 5.77889
62 4M52 FAD 5.92593
63 2VZ0 D64 5.97015
64 2VZ0 NAP 5.97015
65 4F8L AES 6.2069
66 3KO8 NAD 6.41026
67 5I7S NAD 6.52174
68 5I7S E9P 6.52174
69 2Z3Y F2N 6.91358
70 2Z48 A2G 6.91358
71 3VZS NAP 7.00389
72 4YNU FAD 7.40741
73 4YNU LGC 7.40741
74 5WKC PXD 7.65432
75 5WKC F50 7.65432
76 2OFW ADX 7.69231
77 1OAA OAA 7.72201
78 5TVF CGQ 8.77193
79 2C5A NAD 9.49868
80 2C5A GDC 9.49868
81 4UZI IMD 10.6173
82 2JC9 ADN 12.8395
83 4J56 FAD 26.3158
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