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Receptor
PDB id Resolution Class Description Source Keywords
5TB5 2 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF FULL-LENGTH FARNESYLATED AND METHYLATED COMPLEX WITH PDE-DELTA (CRYSTAL FORM I - WITH PARTIALLY DISH YPERVARIABLE REGION) HOMO SAPIENS KRAS4B PDEDELTA PDE6DELTA RAS KRAS ONCOPROTEIN
Ref.: STRUCTURAL BASIS OF RECOGNITION OF FARNESYLATED AND METHYLATED KRAS4B BY PDE DELTA. PROC.NATL.ACAD.SCI.USA V. 113 E6766 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO B:201;
D:201;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
GDP C:202;
A:202;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
FAR C:201;
A:201;
Invalid;
Invalid;
none;
none;
submit data
206.367 C15 H26 CC=C(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5TB5 2 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF FULL-LENGTH FARNESYLATED AND METHYLATED COMPLEX WITH PDE-DELTA (CRYSTAL FORM I - WITH PARTIALLY DISH YPERVARIABLE REGION) HOMO SAPIENS KRAS4B PDEDELTA PDE6DELTA RAS KRAS ONCOPROTEIN
Ref.: STRUCTURAL BASIS OF RECOGNITION OF FARNESYLATED AND METHYLATED KRAS4B BY PDE DELTA. PROC.NATL.ACAD.SCI.USA V. 113 E6766 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 5TB5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 5TB5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 5TB5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5TB5; Ligand: GDP; Similar sites found with APoc: 609
This union binding pocket(no: 1) in the query (biounit: 5tb5.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 2ZFZ ARG None
2 2RGX AP5 3.24324
3 4QRH 0O2 3.24324
4 3FIU POP 3.24324
5 4JZ8 CIT 3.24324
6 2V2V V12 3.24324
7 4E03 ADP 3.78378
8 1P72 ADP 3.78378
9 1AQU A3P 3.78378
10 5L3W GDP 4
11 4NE2 ADP 4
12 4NE2 SH2 4
13 2ZFI ADP 4
14 2J5V PCA 4
15 4TMK T5A 4
16 1G3M PCQ 4
17 1G3M A3P 4
18 4KBF AMP 4
19 5L3S GNP 4.32432
20 5L3V GDP 4.32432
21 1G6O ADP 4.32432
22 5EXT ADP 4.32432
23 1JI0 ATP 4.32432
24 3B7G ANP 4.32432
25 1J99 AND 4.32432
26 2Q2Y ADP 4.66667
27 2Q2Y MKR 4.66667
28 2Y65 ADP 4.66667
29 3BOS CDP 4.66667
30 5I0H ADP BEF 4.66667
31 3ITJ CIT 4.66667
32 1P3D ANP 4.66667
33 3ITJ FAD 4.66667
34 3EZ2 ADP 4.77387
35 1YRB GDP 4.86486
36 3WY9 GDP 4.86486
37 3WYA GDP 4.86486
38 1D2E GDP 4.86486
39 3IO3 ADP 4.86486
40 2OG2 MLI 4.86486
41 3B9Q MLI 4.86486
42 4AG5 ADP 4.86486
43 2YOH WMJ 4.86486
44 1G6H ADP 4.86486
45 2B8T THM 4.86486
46 1VHT BA3 5.04587
47 1BG2 ADP 5.23077
48 3MD0 GDP 5.33333
49 5M04 GDP 5.33333
50 1G41 ADP 5.33333
51 3ZFD ANP 5.33333
52 2DPY ADP 5.33333
53 5VHC BEF ADP 5.33333
54 3FWY ADP 5.40541
55 5J1J ANP 5.40541
56 1SQ5 ADP 5.40541
57 5LB3 ADP 5.40541
58 5ZXD ATP 5.40541
59 1S3G AP5 5.40541
60 3QKT ANP 5.40541
61 3DKP ADP 5.40541
62 1F2U ATP 5.40541
63 5LLB 6YZ 5.40541
64 4IEE AGS 5.40541
65 3VM7 GLC 5.40541
66 2Z5F A3P 5.40541
67 2VHJ ADP 5.40541
68 4KVX ACO 5.76923
69 3COB ADP 5.94595
70 4BAS GNP 5.94595
71 3ZQ6 ADP ALF 5.94595
72 1FP6 ADP 5.94595
73 5WC2 ADP 5.94595
74 1ION ADP 5.94595
75 5K5Z ANP 5.94595
76 4BFW ZVW 5.94595
77 2ZPA ADP 5.94595
78 2ZE7 DST 5.94595
79 1Q20 PLO 5.94595
80 1Q20 A3P 5.94595
81 1K4M CIT 5.94595
82 2ZE7 AMP 5.94595
83 5NM7 GLY 5.94595
84 1M7G ADX 6
85 1M7G ADP 6
86 1M7G AV2 6
87 5I34 GDP 6
88 4D81 ADP 6
89 4R43 GDP 6
90 5UIV ADP 6
91 3L6C MLI 6
92 4IHQ ADP 6
93 4M7V RAR 6
94 5ZB0 ADP 6
95 5ZB0 TYD 6
96 3BER AMP 6
97 6G14 G4P 6.48649
98 3E70 GDP 6.48649
99 1QF5 GDP 6.48649
100 1QF5 RPL 6.48649
101 5AK0 8V1 6.48649
102 5IRN ADP 6.48649
103 4X8O AP5 6.48649
104 1GOJ ADP 6.48649
105 5BQ5 ADP BEF 6.48649
106 3DZD ADP 6.48649
107 1B0U ATP 6.48649
108 1YQT ADP 6.48649
109 5YV5 ADP 6.48649
110 6FAA ADP 6.48649
111 2X7I CIT 6.48649
112 1H74 ADP 6.48649
113 3QVV 3QV 6.48649
114 3QVV A3P 6.48649
115 2ZJ5 ADP 6.48649
116 2QQ0 ANP 6.52174
117 2QQ0 THM 6.52174
118 2QQ0 ADP 6.52174
119 2QQ0 TMP 6.52174
120 3IIJ ADP 6.66667
121 1W7J ADP BEF 6.66667
122 1NN5 2DT 6.66667
123 1NN5 ANP 6.66667
124 2QZ4 ADP 6.66667
125 3QXC ATP 6.66667
126 1P9B GDP 6.66667
127 1KO8 6PG 6.66667
128 3Q9L ATP 6.66667
129 2ZTS ADP 6.66667
130 3FYH ADP 6.66667
131 4QOS ADP 6.66667
132 4TTQ ATP 6.66667
133 2GDJ ANP 6.66667
134 2XAU ADP 6.66667
135 6C90 ADP 6.66667
136 2PEZ GGZ 6.70391
137 2PEZ DAT 6.70391
138 2BEK ATP 7.00389
139 1LVG ADP 7.02703
140 2XTN GTP 7.02703
141 2WHX ADP 7.02703
142 3T34 GDP 7.02703
143 3FB4 AP5 7.02703
144 1OXV ANP 7.02703
145 2JLR ANP 7.02703
146 5LTJ ADP 7.02703
147 5LTJ BEF 7.02703
148 4GBM A3P 7.02703
149 5MEX SZZ 7.02703
150 5H4S RAM 7.02703
151 3RC3 ANP 7.02703
152 3FVQ ATP 7.24234
153 4RD0 GDP 7.33333
154 6CS8 F9Y 7.33333
155 6B4K ANP 7.33333
156 3TMK T5A 7.33333
157 5VGR GDP 7.33333
158 1XKV ATP 7.33333
159 4PX9 ADP 7.33333
160 2ORV 4TA 7.33333
161 3Q9T FAY 7.33333
162 3IUY AMP 7.33333
163 3V2U ATP 7.33333
164 5IRR GSP 7.56757
165 1K6M AGS 7.56757
166 2BIF SIN 7.56757
167 2BIF ANP 7.56757
168 4M52 FAD 7.56757
169 1T8U UAP SGN IDS SGN 7.56757
170 1T8U A3P 7.56757
171 1T5C ADP 7.73639
172 1ZUI SKM 7.7381
173 4H1V GNP 7.85908
174 1XPJ TLA 7.93651
175 2RCN GDP 8
176 4V03 ADP 8
177 4RZ3 ADP 8
178 1NJF AGS 8
179 1NJF ADP 8
180 4GOX A3P 8
181 4IDN GNP 8
182 1Z83 AP5 8
183 2PZE ATP 8
184 4WZ6 ATP 8
185 6B8B ADP 8.03213
186 6AU6 GDP 8.10811
187 3EC1 GDP 8.10811
188 3TK1 GDP 8.10811
189 1CS4 GSP 8.10811
190 4LYA ATP 8.10811
191 3LRE ADP 8.10811
192 2VVG ADP 8.10811
193 1L2T ATP 8.10811
194 5WRJ A3P 8.10811
195 2R4V GSH 8.10811
196 5WRI A3P 8.10811
197 3TBK ANP 8.10811
198 2JAQ DCP 8.10811
199 5BYK A3P 8.10811
200 5BYK OAQ 8.10811
201 2ZPT A3P 8.10811
202 2NCD ADP 8.64865
203 2OFW ADX 8.64865
204 3UIE ANP 8.64865
205 1R6B ADP 8.64865
206 5M7P ADP 8.64865
207 5HR5 ADP 8.64865
208 1JJV ATP 8.64865
209 1I0B PEL 8.64865
210 1KK1 GNP 8.66667
211 3WXM GTP 8.66667
212 1TAD ALF 8.66667
213 1TAD GDP 8.66667
214 3ZS9 ADP ALF 8.66667
215 2WOJ ADP ALF 8.66667
216 5GVR LMR 8.66667
217 3H4S ADP 8.66667
218 4FRZ ADP 8.66667
219 4FCW ADP 8.66667
220 4YDS ATP 8.66667
221 1Z6T ADP 8.66667
222 1AKY AP5 8.66667
223 4LJ9 ACP 8.66667
224 5TIV A3P 8.66667
225 1SKQ GDP 9.18919
226 3HU3 AGS 9.18919
227 2D2F ADP 9.18919
228 5IFS ADP 9.18919
229 1OE0 TTP 9.18919
230 1FNN ADP 9.18919
231 4A4Z ANP 9.18919
232 5W7Q GDP 9.33333
233 5W76 GDP 9.33333
234 5GOE GDP 9.33333
235 1G7C 5GP 9.33333
236 3FKQ ATP 9.33333
237 1E2K TMC 9.33333
238 2OZE AGS 9.33333
239 4OHY ANP 9.33333
240 3BFX A3P 9.33333
241 5CUQ NSC 9.33333
242 4CVN ADP 9.48905
243 1W5T ANP 9.70874
244 1W5T ADP 9.70874
245 2WIC GNP 9.72973
246 1Y63 ADP 9.72973
247 5G3Y ADP 9.72973
248 5MVR ADP 10
249 4JLV ADP 10
250 4ZDJ UTP 10
251 5MZN ADP 10
252 3MGB PAP 10
253 5HSA FAS 10
254 2WJG GDP 10.2703
255 2QEN ADP 10.2703
256 5ZBR ANP 10.2703
257 4XGU ADP 10.2703
258 1SVM ATP 10.2703
259 5W75 GDP 10.6667
260 2XT3 ADP 10.6667
261 1IN4 ADP 10.6667
262 4WOP CTP 10.6667
263 2KIN ADP 10.6667
264 1OS1 PYR 10.6667
265 1OS1 ATP 10.6667
266 3H86 AP5 10.6667
267 2GKS ADP 10.6667
268 1UKZ ADP 10.6667
269 1R0X ATP 10.6667
270 2C78 GNP 10.8108
271 4NON GDP 10.8108
272 2C77 GNP 10.8108
273 1NY5 ADP 10.8108
274 1XP8 AGS 10.8108
275 2F3R G5P 10.8108
276 5G3L SIA 11.1111
277 1DAK DPU 11.1607
278 1DAK ADP 11.1607
279 4ZKD GDP 11.3333
280 5H68 AGS 11.3333
281 5Z69 AGS 11.3333
282 1NHX FTB 11.3333
283 2GMV UN8 11.3333
284 1NHX PEP 11.3333
285 2GMV PEP 11.3333
286 2OBM ADP 11.3333
287 6G47 SIA 11.3333
288 4J0Q GDP 11.3514
289 2FH5 GTP 11.3514
290 1IWE IMP 11.3514
291 1LVK MNT BEF 11.3514
292 5G41 AP5 11.3514
293 1ZIN AP5 11.3514
294 1JJ7 ADP 11.3514
295 4R98 GNH 11.4391
296 2WJH GDP 11.4458
297 2WJH FLC 11.4458
298 5J1S ATP 11.8919
299 2IXE ATP 11.8919
300 2PL3 ADP 11.8919
301 1HTW ADP 12
302 4NU0 AP5 12
303 1U0J ADP 12
304 1VKJ A3P 12
305 6FMC DUE 12.0253
306 4U00 ADP 12.4324
307 1G3Q ADP 12.4324
308 3B5J 12D 12.4324
309 4YMU ATP 12.4324
310 1XX6 ADP 12.4324
311 2CDN ADP 12.4378
312 2FAH GDP 12.6667
313 1KK8 BEF ADP 12.6667
314 1B7T ADP 12.6667
315 1QF9 ADP 12.6667
316 1QF9 C5P 12.6667
317 1QF9 ALF 12.6667
318 4PJ3 ANP 12.6667
319 1GPE FAD 12.6667
320 4LC1 GDP 12.973
321 3PQC GDP 12.973
322 1V8K ANP 12.973
323 2C9O ADP 12.973
324 3A4M ADP 12.973
325 5L3R GCP 12.973
326 2XTZ GSP 13.3333
327 4PFO ADP 13.3333
328 2VB6 ADP BEF 13.3333
329 2FNA ADP 13.3333
330 3EWA ANP 13.354
331 3CNL GNP 13.3588
332 4KFU ACP 13.5135
333 5E5U MLI 13.5135
334 2CBZ ATP 13.9241
335 3U6B GDP 14
336 2HCJ GDP 14
337 2BVN GNP 14
338 1D8T GDP 14
339 4P3Y GDP 14
340 5JBQ GDP 14
341 4G5G GDP 14
342 3U6K GDP 14
343 4PC3 GDP 14
344 4WZA ACP 14
345 4WZA ADP 14
346 4Q1A UDP 14
347 4Q1A 2XZ 14
348 5N69 ADP 14
349 1F9V ADP 14
350 1XEX ATP 14
351 4IOK ADP 14
352 4IOK XPO 14
353 1YTM ATP 14
354 3KTA AP5 14
355 3QF7 ANP 14
356 2B8W ALF 5GP 14
357 4YJ1 ADP 14
358 5XDR ADP 14
359 2A2C NG1 14
360 2A2C ADP 14
361 1NST A3P 14
362 4NCN GTP 14.0541
363 4TMZ GSP 14.0541
364 1OFH ADP 14.0541
365 1RRC ADP 14.0541
366 1OYY AGS 14.0541
367 5TVF PUT 14.1176
368 1MKY GDP 14.5946
369 3CX8 GSP 14.5946
370 1ZCB GDP 14.5946
371 3AB3 GDP 14.5946
372 2AWN ADP 14.5946
373 3RLF ANP 14.5946
374 1QHG ATP 14.6667
375 4HI0 GDP 15.1351
376 2CE7 ADP 15.3333
377 4MKG AP5 15.3333
378 1W4R TTP 15.3333
379 2WZF BGC 15.3333
380 3AB4 THR 15.3333
381 4UXH T5A 15.3333
382 6AIC AMP 15.4206
383 5FHD ADP ALF 15.6757
384 5FTB ANP 15.6757
385 4OI4 ATP 15.6757
386 4QM7 GTP 15.7895
387 3ZIA ADP 16
388 3ZIA ATP 16
389 6H5E ANP 16
390 1PUJ GNP 16.2162
391 2IYL GDP 16.2162
392 4ZG4 VO4 ADP 16.2162
393 4UTG ANP 16.2162
394 5AHM IMP 16.2162
395 1QHH ATP 16.5217
396 4KAX GTP 16.568
397 3NHB ADP 16.6667
398 1Q0H NDP 16.6667
399 4HSE ADP 16.7568
400 5EE5 GTP 16.9591
401 2X77 GDP 17.2973
402 4BQS K2Q 17.2973
403 4BQS ADP 17.2973
404 1GJW GLC 17.3333
405 1IHU AF3 17.8378
406 1IHU ADP 17.8378
407 4MKF AP5 17.8378
408 6DEF GCP 17.8378
409 2ZR9 DTP 17.8378
410 4PPF FLC 17.8378
411 3PCR GTP 17.9012
412 3N5C GDP 17.9012
413 3VMF GTP 18
414 2QG6 NMN 18
415 4P4T GDP 18.3784
416 5U32 GDP 18.6667
417 1UJ2 ADP 19.4595
418 1UJ2 C5P 19.4595
419 2CHG ANP 19.4595
420 2D7D ADP 19.4595
421 1D2N ANP 19.4595
422 5CK5 GDP 20
423 5BN3 ADP 20
424 3DEF GDP 20.5405
425 3W5J GDP 20.5405
426 1CR1 TTP 21.0811
427 1XMV ADP 21.0811
428 5H67 ATP 21.25
429 1GOT GDP 21.3333
430 6A20 ADP 21.3333
431 5X40 ACP 21.3333
432 2ODE ALF GDP 22
433 1GP2 GDP 22
434 2OM2 GDP 22
435 1BH2 GSP 22
436 1Y3A GDP 22
437 1FQK GDP 22
438 1FQJ GDP 22
439 1SVK ALF GDP 22
440 1FQK ALF 22
441 1FQJ ALF 22
442 6CRK GDP 22.1622
443 1RJ9 GCP 22.1622
444 4XTR ATP 22.6667
445 4XVU ATP 22.6667
446 4XTR ADP 22.6667
447 3VX3 ADP 22.7027
448 1W0J ADP 22.7027
449 2V7Q ATP 22.7027
450 2CK3 ADP 22.7027
451 2CK3 ANP 22.7027
452 1W0J ADP BEF 22.7027
453 2V7Q ADP 22.7027
454 1F5N GNP 22.7027
455 5HCN GCP 23.2432
456 5FG3 GDP 23.2432
457 1NRJ GTP 23.7838
458 4TL6 ANP 23.7838
459 1X6V ADP 24
460 1G7S GDP 24.3243
461 1DAR GDP 24.3243
462 4KVA GTP 24.3243
463 2GK6 ADP 24.6667
464 4B47 GDP 25.4054
465 3T1O GDP 25.4054
466 3T12 GDP ALF 25.4054
467 3KJI ADP 25.4054
468 5YT0 GDP 25.9459
469 4M9Q GNP 25.9459
470 2W83 GTP 25.9459
471 2A5F GTP 26.4865
472 1WF3 GNP 27.027
473 3DOE GTP 27.5676
474 4DCT GDP 28.1081
475 2C6Q NDP 28.6667
476 2C6Q IMP 28.6667
477 1J2J GTP 29.1892
478 2J59 GTP 29.1892
479 1O3Y GTP 29.1892
480 1MR3 G3D 29.1892
481 5H7K GDP 29.1892
482 5H7J GCP 29.1892
483 1RE0 GDP 29.7297
484 1S9D GDP 29.7297
485 5KSP GDP 29.7297
486 5KSZ GCP 29.7297
487 1ZD9 GDP 30.2703
488 4YLG GDP 30.2703
489 5KUT GDP 30.2703
490 3AQ4 GDP 30.2703
491 1ZJ6 G3D 30.8108
492 1YZG GDP 31.2849
493 1R4A GNP 33.3333
494 2QN6 GDP 33.3333
495 2IS6 ADP 34
496 3A1S GDP 35.1351
497 2ZEJ GDP 35.3261
498 1F6B GDP 35.6757
499 1WDT GTP 36.2162
500 2QTV GNP 36.7568
501 4ZI2 GNP 37.2973
502 1FZQ GDP 37.2973
503 2GJ8 ALF GDP 37.8378
504 1M2O GNP 37.8378
505 5DI3 GNP 37.8378
506 5KDO GDP 37.8378
507 4GOJ GNP 37.8378
508 1M7B GTP 41.0811
509 1GWN GTP 41.0811
510 1SVI GDP 42.1622
511 3GJ7 GDP 43.2432
512 5OEC GDP 43.2432
513 3GJ5 GDP 43.2432
514 3M1I GTP 43.2432
515 3WYF GTP 43.2432
516 3WYG GTP 43.2432
517 3GJ8 GDP 43.2432
518 3GJ4 GDP 43.2432
519 3GJX GTP 43.2432
520 5BXQ GDP 43.7838
521 5UWQ GNP 43.7838
522 3RAB GNP 43.7838
523 5UWJ GNP 43.7838
524 5UWP GNP 43.7838
525 5UWU GNP 43.7838
526 5UWO GNP 43.7838
527 4HAT GNP 43.7838
528 5UWW GNP 43.7838
529 6CIT GNP 43.7838
530 5UWR GNP 43.7838
531 5UWI GNP 43.7838
532 5UWS GNP 43.7838
533 5DHF GNP 43.7838
534 5UWH GNP 43.7838
535 4DKX GDP 43.7838
536 5UWT GNP 43.7838
537 5LEF GTP 43.7838
538 1WA5 GTP 43.7838
539 3GJ0 GDP 43.7838
540 3GJ3 GDP 43.7838
541 3CH5 GDP 43.7838
542 3REF GDP 43.7838
543 1IBR GNP 43.7838
544 5DI9 GNP 43.7838
545 2EW1 GNP 44.3243
546 1Z0J GTP 44.8649
547 2W2X GSP 44.8649
548 1YVD GNP 45.4054
549 1DS6 GDP 45.4054
550 5UPK GNP 45.4054
551 1A4R GDP 45.4054
552 1A4R GNH 45.4054
553 1NF3 GNP 45.4054
554 3E5H GNP 45.9459
555 4DID GDP 45.9459
556 2NGR GDP 45.9459
557 4YC7 GNP 45.9459
558 2WKQ GTP 45.9459
559 2WMO GTP 45.9459
560 1GRN GDP 45.9459
561 4ITR GDP 45.9459
562 2NGR AF3 45.9459
563 2Y8E GNP 46.3687
564 1E96 GTP 46.4865
565 1I4D GDP 47.027
566 2FJU GSP 47.027
567 1HE1 GDP 47.027
568 3Q72 GNP 47.5676
569 3SBD GNP 47.5676
570 1CXZ GSP 47.5676
571 4D0G GTP 47.5676
572 1KMQ GNP 47.8261
573 1Z0A GDP 48.1081
574 1Z0F GDP 48.1081
575 1Z0K GTP 48.1081
576 3LXR GDP 48.1081
577 2G77 GDP 48.1081
578 1MH1 GNP 48.1081
579 4D0N GDP 48.1081
580 4XSH GSP 48.1081
581 6BCB GSP 48.1081
582 6BCA GSP 48.1081
583 1G4U GDP 48.1081
584 1TX4 ALF GDP 48.1081
585 6BC0 GSP 48.1081
586 5IRC GDP 48.1081
587 5JCP GDP ALF 48.1081
588 1YZQ GNP 48.2353
589 2BME GNP 48.6486
590 2D7C GTP 48.6486
591 1Z2A GDP 48.6486
592 2F9L GDP 48.6486
593 2GCN GDP 48.6486
594 1RYH GNP 48.6486
595 2GCO GNP 48.6486
596 4XOI GTP 48.8889
597 1Z06 GNP 49.1892
598 2A5J GDP 49.1892
599 5Z2M GTP 49.1892
600 3BC1 GNP 49.1892
601 1OIX GDP 49.1892
602 3Q85 GNP 49.1892
603 5XC5 GTP 49.4318
604 1OIV GDP 49.7297
605 2HV8 GTP 49.7297
606 4C4P GNP 49.7297
607 3RWO GDP 49.7297
608 1KY3 GDP 49.7297
609 4U5X GNP 49.7297
Pocket No.: 2; Query (leader) PDB : 5TB5; Ligand: GDP; Similar sites found with APoc: 15
This union binding pocket(no: 2) in the query (biounit: 5tb5.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 6FHQ DE5 None
2 2DT9 THR 3.33333
3 3LEK BCW 4.57516
4 4TQK NAG 5.33333
5 4AG9 COA 6
6 4ITM ATP 6
7 4KOT CE3 6.79012
8 5MEX PAP 7.02703
9 1PVN MZP 8.66667
10 4X7R NTO 10.8108
11 4X7R UDP 10.8108
12 4X7R 3YW 10.8108
13 6F97 FAD 10.8108
14 1A8S PPI 17.2973
15 1JBW ACQ 17.2973
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