Receptor
PDB id Resolution Class Description Source Keywords
5TA6 2.5 Å EC: 2.7.11.21 CRYSTAL STRUCTURE OF PLK1 IN COMPLEX WITH A NOVEL 5,6- DIHYDROIMIDAZOLO[1,5-F]PTERIDINE INHIBITOR. HOMO SAPIENS PLK1 INHIBITOR KINASE STRUCTURE-BASED DRUG DESIGN ANTITUMACTIVITY TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: STRUCTURE-BASED DESIGN AND SAR DEVELOPMENT OF 5,6-DIHYDROIMIDAZOLO[1,5-F]PTERIDINE DERIVATIVES AS POLO-LIKE KINASE-1 INHIBITORS. BIOORG. MED. CHEM. LETT. V. 27 1311 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
79D A:1000;
Valid;
none;
ic50 = 1.5 nM
555.674 C30 H37 N9 O2 CC[C@...
ZN A:1001;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5TA6 2.5 Å EC: 2.7.11.21 CRYSTAL STRUCTURE OF PLK1 IN COMPLEX WITH A NOVEL 5,6- DIHYDROIMIDAZOLO[1,5-F]PTERIDINE INHIBITOR. HOMO SAPIENS PLK1 INHIBITOR KINASE STRUCTURE-BASED DRUG DESIGN ANTITUMACTIVITY TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: STRUCTURE-BASED DESIGN AND SAR DEVELOPMENT OF 5,6-DIHYDROIMIDAZOLO[1,5-F]PTERIDINE DERIVATIVES AS POLO-LIKE KINASE-1 INHIBITORS. BIOORG. MED. CHEM. LETT. V. 27 1311 2017
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3THB ic50 = 2 nM 3TA C23 H25 Cl N6 S Cc1c(cc(cn....
2 2OWB ic50 = 0.34 uM 626 C23 H24 N6 O2 S CN1CCN(CC1....
3 5TA6 ic50 = 1.5 nM 79D C30 H37 N9 O2 CC[C@@H]1c....
70% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2RKU ic50 = 8 nM R78 C28 H39 N7 O3 CC[C@@H]1C....
2 4J53 ic50 = 2 nM 1J4 C27 H34 F3 N7 O3 CN1CCC(CC1....
3 2YAC ic50 = 0.003 uM 937 C24 H27 F3 N8 O3 CN1CCN(CC1....
4 4J52 ic50 = 3 nM 1J3 C28 H37 F N8 O3 CN1CCN(CC1....
5 3FC2 ic50 = 0.87 nM IBI C34 H50 N8 O3 CC[C@@H]1C....
6 4A4L ic50 = 0.015 uM 939 C22 H24 F3 N7 O2 Cn1cc(cc1c....
7 2OU7 ic50 = 140 uM ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
8 3KB7 ic50 = 0.007 uM 071 C23 H28 N8 O2 Cn1c-2c(c(....
9 3THB ic50 = 2 nM 3TA C23 H25 Cl N6 S Cc1c(cc(cn....
10 2OWB ic50 = 0.34 uM 626 C23 H24 N6 O2 S CN1CCN(CC1....
11 5TA6 ic50 = 1.5 nM 79D C30 H37 N9 O2 CC[C@@H]1c....
50% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4I5M ic50 = 0.0088 uM R78 C28 H39 N7 O3 CC[C@@H]1C....
2 4I6H ic50 = 0.005 uM 1C8 C20 H23 N7 O S CC[C@@H]1C....
3 4I5P ic50 = 0.377 uM 1D1 C18 H23 N5 O CC[C@@H]1C....
4 4I6B ic50 = 1.45 uM 11G C14 H20 N4 O CC[C@@H]1C....
5 2RKU ic50 = 8 nM R78 C28 H39 N7 O3 CC[C@@H]1C....
6 4J53 ic50 = 2 nM 1J4 C27 H34 F3 N7 O3 CN1CCC(CC1....
7 2YAC ic50 = 0.003 uM 937 C24 H27 F3 N8 O3 CN1CCN(CC1....
8 4J52 ic50 = 3 nM 1J3 C28 H37 F N8 O3 CN1CCN(CC1....
9 3FC2 ic50 = 0.87 nM IBI C34 H50 N8 O3 CC[C@@H]1C....
10 4A4L ic50 = 0.015 uM 939 C22 H24 F3 N7 O2 Cn1cc(cc1c....
11 2OU7 ic50 = 140 uM ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
12 3KB7 ic50 = 0.007 uM 071 C23 H28 N8 O2 Cn1c-2c(c(....
13 3THB ic50 = 2 nM 3TA C23 H25 Cl N6 S Cc1c(cc(cn....
14 2OWB ic50 = 0.34 uM 626 C23 H24 N6 O2 S CN1CCN(CC1....
15 5TA6 ic50 = 1.5 nM 79D C30 H37 N9 O2 CC[C@@H]1c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 79D; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 79D 1 1
2 R78 0.632 0.905405
3 6TB 0.423611 0.891892
4 IBI 0.412162 0.842105
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5TA6; Ligand: 79D; Similar sites found: 361
This union binding pocket(no: 1) in the query (biounit: 5ta6.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3VPC ADP 0.002308 0.42594 1.41844
2 3KA2 2NC 0.01193 0.40398 1.47783
3 3SJK LYS PRO VAL LEU ARG THR ALA 0.02059 0.41781 1.57895
4 4R78 AMP 0.001619 0.468 1.61812
5 3JQ3 ADP 0.006964 0.43101 1.67598
6 4CYI ATP 0.00005093 0.4441 1.95531
7 4AVB CMP 0.02196 0.4023 1.95531
8 3DGY 2GP 0.01597 0.42347 2.06186
9 4CS9 AMP 0.009142 0.4118 2.1164
10 1TQP ATP 0.00107 0.43302 2.12766
11 4DFU QUE 0.02234 0.41374 2.17391
12 2VQD AP2 0.001753 0.43471 2.23464
13 1I7L ATP 0.001654 0.40633 2.26537
14 3OF1 CMP 0.02083 0.40715 2.43902
15 2BKX F6R 0.01451 0.40744 2.47934
16 2CFM AMP 0.0001469 0.51458 2.51397
17 4U98 ACP 0.001759 0.44671 2.51397
18 1I1E DM2 0.01925 0.41716 2.51397
19 5ENZ UDP 0.00929 0.40952 2.51397
20 2YW2 ATP 0.007471 0.40716 2.51397
21 2YVK MRU 0.01284 0.40308 2.51397
22 4LH7 1X8 0.03425 0.40464 2.78638
23 3NEM ATP 0.01038 0.42234 2.7933
24 1F6D UDP 0.02633 0.40202 2.7933
25 4ZS4 ATP 0.00001384 0.53227 2.9316
26 3ZJX BOG 0.0005312 0.5018 3.07263
27 5MRH Q9Z 0.01602 0.417 3.07263
28 1EHI ADP 0.007416 0.41057 3.07263
29 4KU7 PCG 0.008248 0.42314 3.26797
30 3PDT ADP 0.0000199 0.4421 3.27273
31 3I0O ADP 0.002579 0.45256 3.53982
32 5MW8 ATP 0.0002229 0.43302 3.60934
33 2VD9 IN5 0.005394 0.42404 3.63128
34 5TT6 ATP 0.006041 0.40801 3.63128
35 1CKM GTP 0.02709 0.40521 3.63636
36 2RKN LP3 0.01356 0.40885 3.8961
37 4PU5 ANP 0.006331 0.40409 3.91061
38 4G0P U5P 0.03098 0.40977 4.08163
39 4ANW O92 0.00003085 0.49048 4.18994
40 2VPQ ANP 0.0009082 0.41119 4.18994
41 3W0O ADP 0.002276 0.40118 4.18994
42 3W0O HY0 0.002276 0.40118 4.18994
43 1IA9 ANP 0.00002028 0.52487 4.28571
44 5COU ATP 0.0001745 0.41296 4.41176
45 4D4U FUC NDG GAL FUC 0.01712 0.41834 4.44444
46 4D4U FUC GAL NAG 0.02535 0.40671 4.44444
47 2YNE YNE 0.009088 0.42682 4.46927
48 2YNE NHW 0.009088 0.42682 4.46927
49 4GID 0GH 0.03706 0.40478 4.46927
50 5NCY 8TK 0.0008279 0.4193 4.7486
51 5IQD GNP 0.005953 0.40429 4.91803
52 5IQD RIO 0.006339 0.40429 4.91803
53 3KMT SAH 0.01376 0.40855 5.04202
54 4FE2 ADP 0.00874 0.42191 5.09804
55 5FS0 5JC 0.02901 0.40367 5.21327
56 2V73 SIA 0.03398 0.40521 5.2356
57 2IO8 ADP 0.000198 0.46322 5.30726
58 2V58 LZJ 0.001288 0.4391 5.30726
59 2PYW ADP 0.00008098 0.43792 5.30726
60 2YMZ LAT 0.00655 0.43569 5.38462
61 4YVN EBS 0.01178 0.4298 5.58659
62 5DXT 5H5 0.001178 0.40281 5.86592
63 2BVE PH5 0.03422 0.41129 5.88235
64 4NS0 PIO 0.009532 0.42706 6.01504
65 2Y91 98J 0.04005 0.40239 6.03774
66 4GYI ADP 0.0002315 0.49873 6.14525
67 5I35 ANP 0.00001031 0.45426 6.14525
68 5C4L 4XR 0.002278 0.41478 6.42458
69 4LRJ ANP 0.000006096 0.45764 6.50888
70 1ZP9 ATP 0.00002092 0.5427 6.58915
71 2G30 ALA ALA PHE 0.005368 0.44921 6.58915
72 1ZTH ADP 0.000005959 0.43441 6.58915
73 3AKK ADP 0.0003579 0.41415 6.70391
74 4IAW LIZ 0.012 0.41919 6.91489
75 1GT4 UNA 0.01537 0.40279 6.91824
76 3RE4 TO1 0.00005087 0.40941 6.97674
77 3UDZ ADP 0.00003534 0.44471 6.98324
78 3Q3H UDP 0.02471 0.41142 6.98324
79 3VPB ADP 0.002327 0.4038 7.14286
80 4WW7 AMP 0.00009804 0.44085 7.66284
81 4Z4P SAH 0.01652 0.40132 7.82123
82 3KYG 5GP 5GP 0.008572 0.41465 7.92952
83 2XG5 EC2 0.01003 0.42677 8.25688
84 2XG5 EC5 0.01003 0.42677 8.25688
85 2PUL ACP 0.00005356 0.43397 8.37989
86 4OUC 5ID 0.00003375 0.42847 9.2437
87 1W2D ADP 0.0005946 0.48433 9.43396
88 3KFF ZBT 0.03346 0.40441 9.87654
89 3KFF XBT 0.03346 0.40441 9.87654
90 1PK8 ATP 0.002156 0.41732 10.1896
91 3TDV GDP 0.001175 0.45047 10.4575
92 3Q60 ATP 0.00006582 0.43079 10.6145
93 3ETH ATP 0.0007103 0.41231 10.9859
94 5K2M ADP 0.002328 0.4011 11.3208
95 3X01 AMP 0.0004863 0.50286 11.4504
96 3H9R TAK 0.000001084 0.45906 12.4242
97 4IX4 ADP 0.0002796 0.42458 12.5714
98 2I0D MUT 0.01588 0.40702 13.1313
99 3A6T 8OG 0.0134 0.40558 13.1783
100 2ZHL NAG GAL GAL NAG 0.02355 0.40081 14.1892
101 4XH0 ADP 0.000002252 0.62795 14.2458
102 4BKJ STI 0.0003523 0.43288 14.2857
103 4O1P ANP 0.0000001987 0.51403 15.3631
104 4Q5H ANP 0.0002703 0.41119 16.2011
105 4JR7 GNP 0.000001033 0.49003 17.0391
106 4IJP 1EH 0.000001512 0.50328 17.5978
107 4AUA 4AU 0.000002395 0.47636 17.9153
108 2QHS OCA 0.02751 0.40105 18.1435
109 2QHV OC9 0.01847 0.41381 19.0476
110 5HCY 60D 0.00000008828 0.61022 19.9396
111 2PZI AXX 0.00003309 0.53984 20.3911
112 4I94 ANP 0.00003145 0.43945 20.6667
113 3VHE 42Q 0.000002848 0.5076 20.6704
114 4Y93 746 0.0000003593 0.54589 20.9497
115 1KTG AMP 0.02041 0.41975 21.0145
116 4F9C 0SX 0.000006063 0.4567 21.5084
117 5EOB 5QQ 0.0000004154 0.59492 21.9436
118 1U59 STU 0.0000001307 0.63044 22.6481
119 4Y0X ADP 0.000006064 0.45519 22.6667
120 4FL3 ANP 0.00000004252 0.56155 22.905
121 4G17 0VN 0.000007169 0.45227 23.0303
122 4OAV ACP 0.0000003589 0.49661 23.1844
123 5X8I SQZ 0.000004145 0.47553 23.4104
124 5GZ9 ANP 0.00003589 0.46371 24.2623
125 5M06 ADP 0.0000003083 0.48607 24.3017
126 3KMW ATP 0.00001991 0.44554 25.0923
127 4WHZ 3NL 0.000001033 0.57172 25.6983
128 3TTI KBI 0.000002107 0.52878 25.6983
129 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.02107 0.40689 25.7143
130 4WOV 3SM 0.000000492 0.62877 26.4984
131 5MY8 RXZ 0.000005577 0.50219 26.5363
132 5LXC 7AA 0.0000003985 0.49467 26.5363
133 5AWM ANP 0.00001657 0.42322 26.5363
134 4P5Z Q7M 0.00000006345 0.60738 26.8156
135 4YLL 4E3 0.00001145 0.48493 26.8156
136 1Q8Y ADP 0.00002346 0.46286 27.095
137 1Q8Y ADE 0.000002006 0.44894 27.095
138 5W4W 9WG 0.0000002564 0.57114 27.3743
139 4KBA 1QM 0.00000501 0.51411 27.3743
140 3GNI ATP 0.00000347 0.4863 27.6536
141 3GC0 AMP 0.00000000551 0.5307 27.9635
142 2CSN CKI 0.00138 0.44792 28.2123
143 2PVN P63 0.0000003813 0.56001 28.4091
144 3FHR P4O 0.00000229 0.5671 28.4916
145 3ORK AGS 0.000002793 0.53411 28.6174
146 4OH4 ANP 0.000001271 0.49285 28.8288
147 5LPZ ADP 0.00000006733 0.53104 28.9157
148 5KO1 6UY 0.000002233 0.47502 28.9753
149 5DMZ ADP 0.0000901 0.50124 29.3296
150 4M69 ANP 0.0000009939 0.50544 29.393
151 3E8N VRA 0.000002854 0.44004 29.6188
152 3E8N ATP 0.000002854 0.44004 29.6188
153 3E7O 35F 0.00002455 0.49443 29.8883
154 4EUU BX7 0.0000004236 0.54996 30.094
155 1OPK P16 0.00002256 0.47013 30.1676
156 4NFN 2KC 0.00000182 0.47176 30.4207
157 1VJY 460 0.0000005805 0.55911 30.6931
158 2OO8 RAJ 0.0001851 0.42918 30.9148
159 4CLI 5P8 0.00000000357 0.66781 31.1927
160 3PE2 E1B 0.000003253 0.54822 31.454
161 5HX8 66P 0.00000006196 0.59464 31.457
162 4E93 GUI 0.00000005561 0.55344 31.5642
163 2RIO ADP 0.0000005378 0.49678 31.5642
164 5NKB 8ZT 0.0000001247 0.49153 31.5642
165 5JGA 6KC 0.0000000697 0.59572 31.746
166 5HVJ ANP 0.00001556 0.57849 31.746
167 3LXK MI1 0.0000007459 0.54637 31.8043
168 3KRR DQX 0.0000001695 0.62117 31.8644
169 4IDT T28 0.0000009544 0.48699 32.0225
170 2XVD AS6 0.00000004104 0.59796 32.1192
171 5LPB ADP 0.0000002337 0.48075 32.4324
172 3SXS PP2 0.0000004486 0.51733 32.4627
173 4CRL C1I 0.000003652 0.52916 32.5123
174 3SLS ANP 0.0000002933 0.53009 32.5658
175 2BPM 529 0.000000003522 0.50147 32.6861
176 4AT3 LTI 0.0000008447 0.52701 32.7759
177 5HQ0 LZ9 0.0000007822 0.51061 32.7815
178 5MJA 7O3 0.000000267 0.49512 32.7869
179 3VRY B43 0.000004234 0.52681 32.9609
180 4ASE AV9 0.000004476 0.51602 32.9609
181 4NM5 ADP 0.0004162 0.46465 32.9609
182 2Y6O 1N1 0.0000001264 0.54161 32.9897
183 4EWH T77 0.0000003367 0.55984 33.0909
184 3F7Z 34O 0.00000007624 0.52927 33.1429
185 5BYZ 4WE 0.00000468 0.5212 33.3333
186 1O9U ADZ 0.01338 0.40913 33.4286
187 4YZC STU 0.0000001805 0.58712 33.5196
188 5T8O 76Z 0.00001006 0.5326 33.5244
189 4BTK DTQ 0.000007456 0.46083 33.5312
190 5FBN 5WF 0.0000008889 0.55554 33.5793
191 4BCN T9N 0.00000006516 0.67149 33.6667
192 4CFU 2WC 0.00000001828 0.68814 33.7989
193 2WU6 DKI 0.00000007879 0.55982 33.7989
194 2R5T ANP 0.000006421 0.53536 33.7989
195 4BCM T7Z 0.00000003987 0.47881 33.7989
196 4BCQ TJF 0.000001151 0.4644 33.7989
197 2XMY CDK 0.0000001595 0.62343 33.8926
198 4XV1 904 0.0000002486 0.57578 33.9041
199 3TXO 07U 0.000006221 0.44473 33.9943
200 5LMK 6ZK 0.0000003075 0.48956 34.0067
201 1Y57 MPZ 0.0000004319 0.57907 34.0782
202 2H8H H8H 0.000000286 0.50854 34.0782
203 3PVW QRX 0.00001397 0.5012 34.0782
204 5UKL SIX 0.00006288 0.47125 34.0782
205 1BYG STU 0.0000002156 0.49962 34.1727
206 3SRV S19 0.0000001921 0.50893 34.296
207 3CY2 MB9 0.0000103 0.48267 34.3949
208 4RFM 3P6 0.000003927 0.42297 34.5865
209 3KRL KRL 0.00000006007 0.55291 34.6269
210 4L9I 8PR 0.00003569 0.43492 34.6369
211 5DBX ANP 0.0000009439 0.46347 34.7561
212 4F4P 0SB 0.000001152 0.58079 34.7985
213 4WNK 453 0.00002111 0.49351 34.9162
214 1V0O INR 0.0000002959 0.6067 35.0694
215 1XJD STU 0.0000002966 0.51133 35.0725
216 4U0I 0LI 0.00005105 0.48012 35.2381
217 4Y85 499 0.000006229 0.45707 35.241
218 5UIU 8CG 0.000002582 0.52946 35.2941
219 4N70 2HX 0.000002193 0.55803 35.3659
220 5JFS 6K0 0.000002188 0.54811 35.3896
221 5JKG 6LF 0.0000004538 0.57268 35.4749
222 3PP0 03Q 0.000004085 0.52241 35.4749
223 3C1X CKK 0.00001764 0.51657 35.4749
224 5HES 032 0.000000954 0.51205 35.5049
225 4CQE CQE 0.0000622 0.44976 35.6115
226 3C0G 3AM 0.0000005835 0.47691 35.8974
227 3EKK GS2 0.000000001189 0.57878 36.1564
228 5LI1 ANP 0.000001365 0.50637 36.1582
229 3UIM ANP 0.0000006273 0.50243 36.1963
230 3BZ3 YAM 0.000001329 0.4161 36.2319
231 3BU5 ATP 0.0000002821 0.50844 36.2745
232 3OFM 4B0 0.000006295 0.44721 36.2857
233 5EFQ ADP 0.000001291 0.48989 36.3112
234 5U6C 7YS 0.00000002847 0.56527 36.3129
235 4AG8 AXI 0.000003875 0.47056 36.3924
236 3LXN MI1 0.0000003293 0.59745 36.478
237 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.0000199 0.52568 36.5497
238 2JDR L20 0.0000199 0.52568 36.5497
239 5LI9 ACP 0.000000683 0.59051 36.5714
240 3MVH WFE 0.000007426 0.51139 36.5922
241 5CEO 50D 0.000003076 0.47734 36.6667
242 4NST ADP 0.000004335 0.47219 36.7521
243 1OUK 084 0.000001355 0.60803 36.8715
244 2PVF ACP 0.000004159 0.56886 36.8715
245 3IGO ANP 0.000001964 0.55739 36.8715
246 4UX9 ANP 0.000007801 0.53742 36.8715
247 4LOO SB4 0.00001769 0.45186 36.8715
248 2X2M X2M 0.0000001163 0.54643 36.9427
249 2WQN ADP 0.0000001557 0.65308 37.0968
250 5UR1 YY9 0.00000002889 0.62856 37.1508
251 3GQI ACP 0.000004904 0.55878 37.1508
252 3GC8 B45 0.000002076 0.55635 37.1508
253 4K33 ACP 0.000009332 0.46714 37.2308
254 2JLD AG1 0.00000000367 0.64893 37.4302
255 3ZRM ZRM 0.0000001533 0.5191 37.4302
256 1CM8 ANP 0.00004678 0.43417 37.4302
257 3NW7 LGV 0.0000008378 0.57273 37.4593
258 4OTH DRN 0.00000004917 0.55882 37.5367
259 2ZV2 609 0.0000007538 0.62869 37.5839
260 4YMJ 4EJ 0.000000008344 0.76088 37.8289
261 3DLS ADP 0.000124 0.41491 37.9104
262 3ALN ANP 0.000001463 0.50129 37.9205
263 5BVE 4VG 0.0000003575 0.6049 37.9888
264 4H3Q ANP 0.000002238 0.50696 37.9888
265 3V8S 0HD 0.0000003936 0.49894 37.9888
266 4WB7 ATP 0.0002246 0.41478 37.9888
267 4X7Q 3YR 0.000018 0.53307 38.141
268 2B9F ADP 0.000003755 0.4735 38.2436
269 3PLS ANP 0.00000000358 0.56177 38.255
270 4H3P ANP 0.0000001131 0.52415 38.2682
271 2YAB AMP 0.0000008607 0.49978 38.2682
272 3HMO STU 0.000000003494 0.564 38.3041
273 4GJ3 0XP 0.0000002108 0.57451 38.4106
274 3G5D 1N1 0.0000001685 0.61286 38.4615
275 1K3A ACP 0.000000005801 0.52846 38.4615
276 2B9I ADP 0.00001387 0.53823 38.5269
277 2B9H ADP 0.000004894 0.47519 38.5269
278 2B9J ADP 0.000009533 0.45021 38.5269
279 3HZT J60 0.000004002 0.59257 38.5475
280 3RI1 3RH 0.0000002953 0.55634 38.5475
281 3DAK ANP 0.0000001601 0.50309 38.6207
282 4BHN BH9 0.000002332 0.4938 38.6228
283 2V7O DRN 0.0000004239 0.46009 38.6905
284 3M2W L8I 0.000005304 0.44952 38.796
285 4XLI 1N1 0.0000001114 0.51107 38.806
286 5VCV 1N1 0.000000003271 0.61588 38.8268
287 4WB6 ATP 0.00001912 0.48648 38.8268
288 2QCS ANP 0.00002741 0.48046 38.8268
289 3FHI ANP 0.00006149 0.46736 38.8268
290 2OFV 242 0.000001988 0.54327 38.9892
291 5USZ SKE 0.00000009389 0.58148 39.1003
292 1RE8 BD2 0.000009333 0.52917 39.1061
293 3IDB ANP 0.00006315 0.48817 39.1061
294 1PHK ATP 0.00000228 0.48938 39.2617
295 5TO8 7FM 0.00000006006 0.6102 39.3617
296 5C03 AGS 0.0000004021 0.50105 39.3855
297 5VC5 96M 0.00000000184 0.64809 39.4464
298 2GU8 796 0.000002439 0.56345 39.4659
299 4CSV STI 0.00001669 0.47187 39.6364
300 5IH9 6BF 0.00000004533 0.60942 39.7015
301 4E1Z 0MX 0.0000005565 0.57445 39.8625
302 4QTB 38Z 0.000001379 0.53811 39.9441
303 2WEL K88 0.00000002636 0.46848 40.0612
304 4BFM ANP 0.000000204 0.60653 40.1198
305 5DH3 5BS 0.000001158 0.50228 40.3175
306 4FG8 ATP 0.000002925 0.48939 40.3175
307 2XK9 XK9 0.02097 0.40687 40.3727
308 3QCQ 3Q0 0.0000003349 0.62566 40.3846
309 4YZN 4K5 0.00000001134 0.58893 40.4181
310 2F57 23D 0.00000004459 0.5171 40.5028
311 5LVP ATP 0.0000001042 0.49835 40.5145
312 2VZ6 FEF 0.000002565 0.59388 40.5751
313 4TWP AXI 0.000001918 0.55637 40.5904
314 4U44 3D9 0.0000004108 0.50513 40.6627
315 3SXF BK5 0.000001268 0.54935 40.7821
316 4AU8 Z3R 0.0000006064 0.46966 40.8784
317 4Y8D 49J 0.000001164 0.5872 40.8824
318 3GGF GVD 0.0000008174 0.48364 41.196
319 5DRB 5FJ 0.00001707 0.4147 41.2371
320 2Z7R STU 0.0000000229 0.57105 41.433
321 1UNH IXM 0.00000001848 0.51994 41.4384
322 3O0G 3O0 0.0000001012 0.51229 41.4384
323 5N87 N66 0.0000000192 0.62446 41.5335
324 4QMN DB8 0.000000007064 0.64195 41.6129
325 4USF 6UI 0.000001876 0.51432 41.7763
326 2X4Z X4Z 0.00000008911 0.59562 41.8919
327 4DC2 ADE 0.0000008284 0.41309 41.8994
328 4C2V YJA 0.0000004044 0.56119 42.1053
329 5EKO N17 0.001011 0.40759 42.1788
330 4G31 0WH 0.00002966 0.45207 42.4749
331 1U5R ATP 0.0000002313 0.61915 42.5287
332 2HK5 1BM 0.000000474 0.51576 42.5926
333 1ZY5 ANP 0.0000001776 0.50107 42.9043
334 4C2W ANP 0.00000004161 0.49802 43.0108
335 4JDI ANP 0.00000108 0.50521 43.0168
336 5H2U 1N1 0.00000003377 0.53857 43.0712
337 4L3L 5FI 0.000001689 0.53673 43.0921
338 5DEY 59T 0.0000000177 0.65168 43.0976
339 3TKI S25 0.00000006887 0.62669 43.3437
340 3KN5 ANP 0.00002006 0.42672 43.3846
341 5DA3 58V 0.00000001441 0.71433 43.3962
342 5JZJ AN2 0.000001248 0.48303 43.4343
343 2HY0 306 0.00000001225 0.70681 43.4783
344 5EYK 5U5 0.0000001792 0.57053 43.4783
345 4KS7 X4Z 0.00000001508 0.64025 43.4931
346 2VN9 GVD 0.00000001817 0.50227 43.5216
347 5AX9 4KT 0.0000007719 0.49609 43.8312
348 4NW6 2NS 0.000001025 0.50984 43.9628
349 4WNP 3RJ 0.000000005625 0.53196 45.2962
350 2YAK OSV 0.0000002138 0.5721 45.9649
351 2WEI VGG 0.0000001489 0.49882 45.993
352 3AQV TAK 0.00002654 0.4441 46.0145
353 4D2S DYK 0.00000009952 0.50418 46.1268
354 5A6N U7E 0.0000001164 0.5296 46.6431
355 2A19 ANP 0.00000001316 0.71629 46.831
356 5G1X ADP 0.0000004102 0.49677 47.0175
357 5L8L ADP 0.0000001032 0.48922 47.0175
358 4A4X JUP 0.0000002076 0.56089 47.3118
359 5LXM ADP 0.0000004458 0.49364 47.3498
360 5UOX 8GY 0.000002818 0.49587 47.6015
361 5EW9 5VC 0.000001209 0.61031 49.8155
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