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Receptor
PDB id Resolution Class Description Source Keywords
5T67 1.6 Å EC: 2.-.-.- X-RAY STRUCTURE OF THE KIJD1 C3-METHYLTRANSFERASE FROM ACTIN KIJANIATA IN COMPLEX WITH SAH AND DTDP-SUGAR PRODUCT ACTINOMADURA KIJANIATA C3-METHYLTRANSFERASE ANTITUMOR ANTIBIOTIC KIJANIMICIN TR
Ref.: STRUCTURAL STUDIES ON KIJD1, A SUGAR C-3'-METHYLTRA PROTEIN SCI. V. 25 2282 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:505;
B:504;
A:504;
A:506;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
ZN A:501;
B:501;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
CL A:509;
Invalid;
none;
submit data
35.453 Cl [Cl-]
MG A:507;
A:508;
Invalid;
Invalid;
none;
none;
submit data
24.305 Mg [Mg+2...
SAH B:502;
A:502;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
JHZ B:503;
A:503;
Valid;
Valid;
none;
none;
submit data
543.356 C17 H27 N3 O13 P2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5T67 1.6 Å EC: 2.-.-.- X-RAY STRUCTURE OF THE KIJD1 C3-METHYLTRANSFERASE FROM ACTIN KIJANIATA IN COMPLEX WITH SAH AND DTDP-SUGAR PRODUCT ACTINOMADURA KIJANIATA C3-METHYLTRANSFERASE ANTITUMOR ANTIBIOTIC KIJANIMICIN TR
Ref.: STRUCTURAL STUDIES ON KIJD1, A SUGAR C-3'-METHYLTRA PROTEIN SCI. V. 25 2282 2016
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5T6B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 5T67 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 5T64 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
70% Homology Family (13)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 4E33 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4E2W - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
3 4E2Z - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
4 4E30 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 4E2X - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 4E32 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 4E2Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 4E31 - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
9 3NDI - SAM C15 H22 N6 O5 S C[S@@+](CC....
10 3NDJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
11 5T6B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 5T67 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
13 5T64 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 4RVD - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 4RVG - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 4RV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 4RVH - 3YN C16 H24 N2 O14 P2 C[C@@H]1C(....
5 4E33 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 4E2W - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
7 4E2Z - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
8 4E30 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
9 4E2X - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 4E32 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
11 4E2Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 4E31 - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
13 3NDI - SAM C15 H22 N6 O5 S C[S@@+](CC....
14 3NDJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
15 5T6B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 5T67 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
17 5T64 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Ligand no: 2; Ligand: JHZ; Similar ligands found: 57
No: Ligand ECFP6 Tc MDL keys Tc
1 JHZ 1 1
2 AKM 0.74 0.974684
3 DWN 0.72449 0.974026
4 3YN 0.707071 0.948052
5 0N2 0.666667 0.961538
6 TTP 0.638298 0.884615
7 3R2 0.637255 0.935897
8 TRH 0.637255 0.923077
9 18T 0.637255 0.923077
10 1JB 0.637255 0.923077
11 T46 0.634615 0.923077
12 DAU 0.631068 0.898734
13 TYD 0.630435 0.884615
14 T3F 0.625 0.948718
15 T3Q 0.625 0.948718
16 0FX 0.613208 0.948718
17 TDX 0.605769 0.910256
18 MMF 0.598131 0.924051
19 QDM 0.587156 0.9125
20 TLO 0.582524 0.886076
21 FNF 0.581818 0.935897
22 1YF 0.581818 0.935897
23 4TG 0.576577 0.935897
24 TMP 0.576087 0.871795
25 FUH 0.542373 0.948718
26 QUH 0.542373 0.948718
27 DT DT DT 0.495413 0.884615
28 DT DT PST 0.491228 0.841463
29 TBD 0.490196 0.851852
30 T5A 0.488 0.837209
31 7SG 0.481481 0.858824
32 TQP 0.481481 0.858824
33 DT DT DT DT DT 0.473684 0.886076
34 T5K 0.467153 0.848837
35 T4K 0.467153 0.848837
36 ATY 0.457944 0.910256
37 LLT 0.456522 0.794872
38 THM 0.456522 0.794872
39 AZD 0.449541 0.831325
40 0DN 0.446809 0.759494
41 UFP 0.44 0.804878
42 TPE 0.435897 0.911392
43 NYM 0.431373 0.897436
44 DT ME6 DT 0.429688 0.841463
45 THP 0.427184 0.858974
46 T3P 0.424242 0.835443
47 BRU 0.421569 0.804878
48 5HU 0.421569 0.860759
49 4TA 0.421053 0.804598
50 ATM 0.420561 0.819277
51 5IU 0.417476 0.804878
52 FDM 0.417476 0.817073
53 ABT 0.413793 0.811765
54 TXS 0.411765 0.743902
55 D3T 0.407407 0.860759
56 DUT 0.407407 0.846154
57 T3S 0.403846 0.765432
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5T67; Ligand: SAH; Similar sites found with APoc: 358
This union binding pocket(no: 1) in the query (biounit: 5t67.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL GLC NBU None
2 2BOS GLA GAL GLC None
3 1O68 KIV 1.09091
4 2NPX NAD 1.20192
5 1F8G NAD 1.30208
6 1U2Z SAH 1.44231
7 5Z20 NAI 1.44928
8 3ITJ CIT 1.47929
9 1SC6 NAD 1.48515
10 1X14 NAD 1.49626
11 4DMG SAM 1.52672
12 4V3I ASP LEU THR ARG PRO 1.55642
13 5XNC MTA 1.61725
14 3MAG SAH 1.62866
15 3TKY SAH 1.63043
16 1EBF NAD 1.67598
17 5E58 CPZ 1.68269
18 1GET NAP 1.68269
19 1GET FAD 1.68269
20 3MCT SAH 1.6835
21 4YAC NAI 1.6835
22 3U31 NAD 1.72414
23 3GCZ SAM 1.77305
24 4XB2 NDP 1.79104
25 3EVG SAH 1.81818
26 3KLJ FAD 1.81818
27 3A4T SFG 1.82482
28 2HJR APR 1.82927
29 3TLJ SAH 1.87668
30 1A5Z NAD 1.88088
31 2JHP SAH 1.92308
32 5W7R SAH 1.92308
33 5L2R MLA 1.92308
34 3S1S SAH 1.92308
35 1N2X SAM 1.99336
36 3GFB NAD 2
37 3VSE SAH 2.01005
38 2DFV NAD 2.01729
39 3O7W SAM 2.04082
40 4M73 SAH 2.07715
41 4M73 M72 2.07715
42 2AWN ADP 2.09974
43 1CER NAD 2.1148
44 1UP7 NAD 2.16346
45 1DJN ADP 2.16346
46 4OPC PGT 2.16346
47 4OPC FDA 2.16346
48 5E9W SAH 2.24359
49 5E8J SAH 2.24359
50 5DLY SAH 2.25564
51 5DLY 5D7 2.25564
52 2FJK 13P 2.29508
53 2RBK VN4 2.29885
54 3FRH SAH 2.37154
55 1MV8 NAD 2.40385
56 1MUU NAD 2.40385
57 2NVK NAP 2.40385
58 1VJT NAD 2.40385
59 3GD4 NAD 2.40385
60 5U8U FAD 2.40385
61 4BLW SAH 2.42215
62 5YJI 8WO 2.46479
63 5YJI SAH 2.46479
64 1LTH NAD 2.50784
65 2HK9 ATR 2.54545
66 1KYQ NAD 2.55474
67 1QH9 LAC 2.58621
68 3OJO NAD 2.64423
69 5MQ6 NDP 2.64423
70 3L9W AMP 2.66344
71 4DCM SAM 2.66667
72 2JBM SRT 2.67559
73 5Y8L NAD 2.71186
74 2POC BG6 2.7248
75 5YF1 SFG 2.76243
76 5YF1 8V0 2.76243
77 2OOR NAD 2.87356
78 5KXE 6Y2 2.88066
79 1WY7 SAH 2.89855
80 4OM8 NAD 2.91262
81 5EEH SAH 2.92553
82 4Y9D NAI 2.95082
83 2CBZ ATP 2.95359
84 1V6A TRE 3.01205
85 3GRU AMP 3.05085
86 3W9F I3P 3.07692
87 3I7S PYR 3.08219
88 1P31 EPU 3.125
89 5ICE SAH 3.125
90 1NW5 SAM 3.1348
91 1WG8 SAM 3.15789
92 3WV8 ATP 3.21101
93 1RZM E4P 3.25444
94 1Z82 G3P 3.28358
95 1Z82 G3H 3.28358
96 1J49 NAD 3.3033
97 3I53 SAH 3.31325
98 6BQ6 TER 3.32326
99 1O0S NAI 3.36538
100 5H81 NAP 3.36538
101 2WPF FAD 3.36538
102 2WPF WPF 3.36538
103 1WDK NAD 3.36538
104 2Q28 ADP 3.36879
105 4A6D SAM 3.39943
106 4PIO AVI 3.40557
107 4PIO SAH 3.40557
108 3DMH SAM 3.41207
109 3DMH GMP 3.41207
110 4UCC ZKW 3.43348
111 1EZ4 NAD 3.45912
112 4RDH AMP 3.47222
113 4RDI ATP 3.47222
114 3MB5 SAM 3.52941
115 5TVM PUT 3.52941
116 1KYZ SAH 3.56164
117 2F1K NAP 3.58423
118 6DUB SAH 3.6036
119 4C4A SAH 3.60577
120 3DXY SAM 3.66972
121 3A27 SAM 3.67647
122 5D4V SAH 3.73134
123 3GDH SAH 3.73444
124 6B92 SAH 3.7415
125 1W3T 3GR 3.7415
126 4RL4 PPV 3.77358
127 3ICS ADP 3.84615
128 3ICT ADP 3.84615
129 3PT9 SAH 3.84615
130 1X87 NAD 3.84615
131 5YV5 ADP 3.84615
132 1YQT ADP 3.84615
133 5J5Z FAD 3.84615
134 5MPT SAH 3.86473
135 1NV8 SAM 3.87324
136 1NV8 MEQ 3.87324
137 6ACS CIT 3.87597
138 2EFJ SAH 3.90625
139 5THY SAH 3.95062
140 5THZ SAH 3.95062
141 4D79 ATP 3.98551
142 5ME4 HP4 4.0146
143 5OJL TXP 4.02685
144 2ZIF SAM 4.0404
145 2PT9 S4M 4.04984
146 2PT9 2MH 4.04984
147 1G55 SAH 4.08163
148 3SQP FAD 4.08654
149 1OBB NAD 4.08654
150 2VT3 ATP 4.18605
151 5MW4 5JU 4.19162
152 2QES ADE 4.21456
153 4AZW SAM 4.32692
154 2IZ1 ATR 4.32692
155 3EGI ADP 4.36893
156 6GFK SAH 4.38247
157 1TE2 PGA 4.42478
158 2UYQ SAM 4.51613
159 3VYW SAM 4.54545
160 1ZQ9 SAM 4.5614
161 3X0D SAH 4.56731
162 2WPB ZZI 4.56731
163 3SSO SAH 4.56731
164 5X7Q GLC GLC GLC 4.56731
165 5X7Q GLC GLC GLC GLC 4.56731
166 2EG5 SAH 4.56989
167 2DPM SAM 4.57746
168 2P41 SAH 4.59016
169 2I7C AAT 4.59364
170 1G60 SAM 4.61538
171 3KP6 SAL 4.63576
172 2FK8 SAM 4.71698
173 5BXQ GDP 4.72441
174 4UP3 NDP 4.77707
175 1RJD SAM 4.79042
176 2JJQ SAH 4.80769
177 1QAN SAH 4.91803
178 2O07 MTA 4.93421
179 2O07 SPD 4.93421
180 2A14 SAH 4.94297
181 3FZG SAM 5
182 2D2I NAP 5
183 1NBU PH2 5.04202
184 1FUR MLT 5.04808
185 1JG3 ADN 5.10638
186 1L5Y BEF 5.16129
187 2BZG SAH 5.17241
188 1Y8Q ATP 5.20231
189 2DT5 NAD 5.21327
190 3G89 SAM 5.22088
191 2CDU ADP 5.28846
192 5GSN NAP 5.28846
193 3A25 SAM 5.31561
194 3FPF MTA 5.36913
195 3FPF TNA 5.36913
196 4RM0 FUC NAG GAL 5.37975
197 3BGD SAH 5.38462
198 3BGD PM6 5.38462
199 5HJM MTA 5.39773
200 5W7K SAH 5.44872
201 2YVJ NAI 5.50459
202 2ZWA SAH 5.52885
203 1PJS NAD 5.52885
204 3FUU ADN 5.53506
205 1L1E SAH 5.57491
206 4YT4 FE9 5.6
207 1RJW ETF 5.60472
208 3B20 NAD 5.60472
209 4B4U NAP 5.61056
210 1XDS SAM 5.61497
211 1QZZ SAM 5.61497
212 5F7J ADE 5.625
213 3QOX SAH 5.6338
214 5FUB SAH 5.63798
215 2G5C NAD 5.69395
216 1LSS NAD 5.71429
217 5H06 MAL 5.76923
218 2GVC FAD 5.76923
219 1VQW FAD 5.76923
220 1RL4 BL5 5.85106
221 2CZL TLA 5.88235
222 6AA8 NAD 5.96026
223 4POO SAM 6
224 1DSS NAD 6.00601
225 5OSW CIT 6.00962
226 6C4N NAP 6.00962
227 2XVM SAH 6.03015
228 5ZXD ATP 6.04396
229 3QV1 NAD 6.09756
230 1KNM LAT 6.15385
231 4TXI FAD 6.25
232 4YUW 4JU 6.25
233 3G5N PB2 6.25
234 4YUW S4M 6.25
235 2BRY FAD 6.25
236 3TKA SAM 6.34006
237 2EJU SAH 6.34921
238 3N8K D1X 6.39535
239 6D6Y SAH 6.49038
240 1LVL NAD 6.49038
241 3W6X HZP 6.55022
242 4IWN GEK 6.55022
243 1UAY ADN 6.61157
244 1P77 ATR 6.61765
245 5E1M PRO PRO LYS ARG ILE ALA 6.639
246 5E1M SAH 6.639
247 2O66 FLC 6.66667
248 3GU3 SAH 6.69014
249 1J5P NAD 6.71937
250 4ONQ SFG 6.72269
251 1PL6 NAD 6.74157
252 5MGZ SAH 6.77966
253 4KOA NDP 6.90691
254 4JZ8 CIT 6.94006
255 2FKA BEF 6.97674
256 1BXG NAD 7.02247
257 1P1C SAH 7.03518
258 3VC1 GST 7.05128
259 3VC1 SAH 7.05128
260 5OFW 9TW 7.17489
261 5ERG SAM 7.31071
262 5YEC ATP 7.35294
263 3G2O SAM 7.35786
264 5M58 SAH 7.3913
265 5DM1 SAH 7.49064
266 5DM1 5D7 7.49064
267 1O94 ADP 7.57576
268 1BW9 NAD 7.58427
269 1C1X NAD 7.60563
270 5JE8 NAD 7.61589
271 5B09 4MX 7.69231
272 5GWX SAM 7.74648
273 5GWX SAR 7.74648
274 1JQ3 AAT 7.77027
275 1G6H ADP 7.7821
276 5FA5 MTA 7.93269
277 4GQB 0XU 7.93269
278 1XCL SAH 8.08511
279 1HYH NAD 8.09062
280 5LD5 NAD 8.10056
281 5ZZ6 ADP 8.17308
282 5ZZ6 NAD 8.17308
283 5FTW SAH 8.20312
284 5N53 8NB 8.20513
285 5AHO TLA 8.33333
286 3OFK SAH 8.7963
287 1V59 NAD 8.89423
288 4M37 SAH 9.0379
289 4M38 SAH 9.0379
290 1Z3C SA8 9.39597
291 3TL1 JRO 9.43396
292 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 9.52381
293 5KOK SAH 9.57179
294 5KOK R9T 9.57179
295 5KOK S9T 9.57179
296 2AOT SAH 9.58904
297 1JQD SAH 9.58904
298 1JQD HSM 9.58904
299 1R18 SAH 9.69163
300 1BC5 SAH 10.0372
301 4IF4 BEF 10.0962
302 5ZW3 SAH 10.2222
303 5W7M SAH 10.2564
304 5WP5 SAH 10.3365
305 5WP4 SAH 10.3365
306 2RGO FAD 10.3365
307 4JWK CTN 10.3627
308 4ZGS NAD 10.3627
309 3LCC SAH 10.6383
310 5XLX SAH 10.6383
311 2PWY SAH 10.8527
312 2VDV SAM 10.9756
313 2NSJ C2R 11.2426
314 3JWH SAH 11.5207
315 2PXX SAH 11.6279
316 1Q9I TEO 11.7788
317 1Q9I FAD 11.7788
318 2V7Q ADP 12.3288
319 5X62 SAH 12.5616
320 1OMO NAD 12.7329
321 3H8V ATP 13.0137
322 4Y30 SAH 13.1054
323 4Y30 49L 13.1054
324 1DL5 SAH 13.2492
325 4II2 ATP 13.253
326 6GKV SAH 13.3903
327 4ODV GP1 Z9M 13.5135
328 3IWD M2T 14.5161
329 3GWZ SAH 14.6341
330 3GXO SAH 14.6341
331 4QTU SAM 15.3846
332 4FZV SAM 15.4812
333 5IL1 SAM 15.566
334 2YX1 SFG 15.7738
335 1TPY SAH 16.3763
336 5FWA J7C 16.5865
337 1VE3 SAM 16.7401
338 1KPG SAH 17.4216
339 4R6W SAH 17.8295
340 4R6W PC 17.8295
341 1KPH SAH 18.4669
342 4OBW SAM 18.677
343 5L95 AMP 18.75
344 4URG C2E 19.1617
345 1IM8 SAI 20.082
346 2AG8 NAP 20.1521
347 5DWQ SFG 20.9169
348 5DX1 SFG 20.9169
349 5DX8 SFG 20.9169
350 5DXA SFG 20.9169
351 5DX0 SFG 20.9169
352 6ARJ BW4 20.9169
353 6ARJ SAH 20.9169
354 3Q87 SAM 22.9412
355 3DUW SAH 24.6637
356 2NXE SAM 25.9843
357 3VPB GLU 26.7857
358 2HMT NAI 36.1111
Pocket No.: 2; Query (leader) PDB : 5T67; Ligand: JHZ; Similar sites found with APoc: 368
This union binding pocket(no: 2) in the query (biounit: 5t67.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL GLC NBU None
2 2BOS GLA GAL GLC None
3 3CMJ SRT 0.961538
4 1F8G NAD 1.30208
5 1L7E NAI 1.30208
6 1U2Z SAH 1.44231
7 5Z20 NAI 1.44928
8 3ITJ CIT 1.47929
9 1SC6 NAD 1.48515
10 1X14 NAD 1.49626
11 4DMG SAM 1.52672
12 5XNC MTA 1.61725
13 3MAG SAH 1.62866
14 3TKY SAH 1.63043
15 1EBF NAD 1.67598
16 5E58 CPZ 1.68269
17 5VN0 FAD 1.68269
18 5VN0 NAI 1.68269
19 3MCT SAH 1.6835
20 4YAC NAI 1.6835
21 3U31 NAD 1.72414
22 3GCZ SAM 1.77305
23 4XB2 NDP 1.79104
24 3KLJ FAD 1.81818
25 3EVG SAH 1.81818
26 3A4T SFG 1.82482
27 2HJR APR 1.82927
28 3TLJ SAH 1.87668
29 3AJM 4IP 1.87793
30 1A5Z NAD 1.88088
31 2JHP SAH 1.92308
32 5W7R SAH 1.92308
33 5L2R MLA 1.92308
34 3S1S SAH 1.92308
35 1N2X SAM 1.99336
36 3GFB NAD 2
37 3VSE SAH 2.01005
38 2DFV NAD 2.01729
39 3O7W SAM 2.04082
40 4M73 SAH 2.07715
41 4M73 M72 2.07715
42 1RM4 NDP 2.07715
43 3OLL EST 2.08333
44 2AWN ADP 2.09974
45 1CER NAD 2.1148
46 1UP7 NAD 2.16346
47 1DJN ADP 2.16346
48 3IHG FAD 2.16346
49 5E9W SAH 2.24359
50 5E8J SAH 2.24359
51 5DLY SAH 2.25564
52 5DLY 5D7 2.25564
53 2RBK VN4 2.29885
54 3Q3C NAD 2.34114
55 3FRH SAH 2.37154
56 1MV8 NAD 2.40385
57 1MUU NAD 2.40385
58 2NVK NAP 2.40385
59 1VJT NAD 2.40385
60 3S5W FAD 2.40385
61 4BLW SAH 2.42215
62 6BXO SAH 2.44648
63 5YJI 8WO 2.46479
64 5YJI SAH 2.46479
65 1LTH NAD 2.50784
66 1H0A I3P 2.53165
67 2HK9 ATR 2.54545
68 1KYQ NAD 2.55474
69 1QH9 LAC 2.58621
70 1ZOS MTM 2.6087
71 3OJO NAD 2.64423
72 5MQ6 NDP 2.64423
73 3L9W AMP 2.66344
74 4DCM SAM 2.66667
75 2JBM SRT 2.67559
76 5Y8L NAD 2.71186
77 2AF6 FAD 2.71318
78 6F7L FAD 2.71493
79 4E5N NAD 2.72727
80 5YF1 SFG 2.76243
81 5YF1 8V0 2.76243
82 2OOR NAD 2.87356
83 5KXE 6Y2 2.88066
84 1GPM AMP 2.88462
85 1WY7 SAH 2.89855
86 4OM8 NAD 2.91262
87 5EEH SAH 2.92553
88 4Y9D NAI 2.95082
89 1V6A TRE 3.01205
90 3GRU AMP 3.05085
91 3W9F I3P 3.07692
92 3I7S PYR 3.08219
93 1WP4 NDP 3.11419
94 1P31 EPU 3.125
95 1P3D UMA 3.125
96 5ICE SAH 3.125
97 1NW5 SAM 3.1348
98 1WG8 SAM 3.15789
99 3WV8 ATP 3.21101
100 1RZM E4P 3.25444
101 1Z82 G3P 3.28358
102 1Z82 G3H 3.28358
103 1J49 NAD 3.3033
104 3I53 SAH 3.31325
105 6BQ6 TER 3.32326
106 1O0S NAI 3.36538
107 1WDK NAD 3.36538
108 5H81 NAP 3.36538
109 2Q28 ADP 3.36879
110 4A6D SAM 3.39943
111 4PIO AVI 3.40557
112 4PIO SAH 3.40557
113 3DMH SAM 3.41207
114 3DMH GMP 3.41207
115 1EZ4 NAD 3.45912
116 4RDH AMP 3.47222
117 4RDI ATP 3.47222
118 3MB5 SAM 3.52941
119 1KYZ SAH 3.56164
120 2F1K NAP 3.58423
121 6DUB SAH 3.6036
122 4C4A SAH 3.60577
123 3GJ5 GDP 3.61991
124 3DXY SAM 3.66972
125 3A27 SAM 3.67647
126 3WBZ ATP 3.69004
127 5D4V SAH 3.73134
128 3GDH SAH 3.73444
129 6B92 SAH 3.7415
130 4RL4 PPV 3.77358
131 3ICS ADP 3.84615
132 3ICT ADP 3.84615
133 3PT9 SAH 3.84615
134 1X87 NAD 3.84615
135 5YV5 ADP 3.84615
136 4JK3 NAD 3.861
137 5MPT SAH 3.86473
138 1NV8 SAM 3.87324
139 1NV8 MEQ 3.87324
140 6ACS CIT 3.87597
141 2EFJ SAH 3.90625
142 5THY SAH 3.95062
143 5THZ SAH 3.95062
144 4D79 ATP 3.98551
145 5ME4 HP4 4.0146
146 5OJL TXP 4.02685
147 2ZIF SAM 4.0404
148 2PT9 S4M 4.04984
149 2PT9 2MH 4.04984
150 1G55 SAH 4.08163
151 1OBB NAD 4.08654
152 4X8D AVI 4.08654
153 2VT3 ATP 4.18605
154 5MW4 5JU 4.19162
155 4AZW SAM 4.32692
156 2IZ1 ATR 4.32692
157 3HQP FDP 4.32692
158 3EGI ADP 4.36893
159 6GFK SAH 4.38247
160 1TE2 PGA 4.42478
161 2UYQ SAM 4.51613
162 3VYW SAM 4.54545
163 1ZQ9 SAM 4.5614
164 3X0D SAH 4.56731
165 2WPB ZZI 4.56731
166 5X7Q GLC GLC GLC 4.56731
167 3SSO SAH 4.56731
168 2EG5 SAH 4.56989
169 2DPM SAM 4.57746
170 2P41 SAH 4.59016
171 2I7C AAT 4.59364
172 1G60 SAM 4.61538
173 3KP6 SAL 4.63576
174 2A5J GDP 4.71204
175 2FK8 SAM 4.71698
176 5BXQ GDP 4.72441
177 4UP3 NDP 4.77707
178 1RJD SAM 4.79042
179 1NYT NAP 4.79705
180 2F2H XTG 4.80769
181 2JJQ SAH 4.80769
182 1QAN SAH 4.91803
183 2Q7V FAD 4.92308
184 2HZL PYR 4.93151
185 2O07 MTA 4.93421
186 2O07 SPD 4.93421
187 2A14 SAH 4.94297
188 3FZG SAM 5
189 2D2I NAP 5
190 1FUR MLT 5.04808
191 1JG3 ADN 5.10638
192 2BZG SAH 5.17241
193 1Y8Q ATP 5.20231
194 2DT5 NAD 5.21327
195 3G89 SAM 5.22088
196 2CDU ADP 5.28846
197 5GSN NAP 5.28846
198 2CDU FAD 5.28846
199 5GSN FAD 5.28846
200 3A25 SAM 5.31561
201 3FPF MTA 5.36913
202 3FPF TNA 5.36913
203 3H5N ATP 5.38244
204 3BGD SAH 5.38462
205 3BGD PM6 5.38462
206 5HJM MTA 5.39773
207 5W7K SAH 5.44872
208 2YVJ NAI 5.50459
209 2ZWA SAH 5.52885
210 1PJS NAD 5.52885
211 3FUU ADN 5.53506
212 1L1E SAH 5.57491
213 4YT4 FE9 5.6
214 1RJW ETF 5.60472
215 3B20 NAD 5.60472
216 4B4U NAP 5.61056
217 1XDS SAM 5.61497
218 1QZZ SAM 5.61497
219 3QOX SAH 5.6338
220 5FUB SAH 5.63798
221 2G5C NAD 5.69395
222 1LSS NAD 5.71429
223 1Z0A GDP 5.74713
224 5H06 MAL 5.76923
225 1VQW FAD 5.76923
226 5G3U FDA 5.76923
227 2GVC FAD 5.76923
228 2GV8 FAD 5.76923
229 1RL4 BL5 5.85106
230 6AA8 NAD 5.96026
231 4POO SAM 6
232 1DSS NAD 6.00601
233 6C4N NAP 6.00962
234 2XVM SAH 6.03015
235 5ZXD ATP 6.04396
236 3QV1 NAD 6.09756
237 4TXI FAD 6.25
238 2BRY FAD 6.25
239 3TKA SAM 6.34006
240 2EJU SAH 6.34921
241 3N8K D1X 6.39535
242 1KJ1 MAN 6.42202
243 3VPH OXM 6.45161
244 6D6Y SAH 6.49038
245 1LVL NAD 6.49038
246 3GJ8 GDP 6.52174
247 4IWN GEK 6.55022
248 3W6X HZP 6.55022
249 1UAY ADN 6.61157
250 1P77 ATR 6.61765
251 5E1M PRO PRO LYS ARG ILE ALA 6.639
252 5E1M SAH 6.639
253 2O66 FLC 6.66667
254 3GU3 SAH 6.69014
255 1J5P NAD 6.71937
256 4ONQ SFG 6.72269
257 1PL6 NAD 6.74157
258 5MGZ SAH 6.77966
259 4KOA NDP 6.90691
260 2FKA BEF 6.97674
261 1BXG NAD 7.02247
262 1P1C SAH 7.03518
263 3VC1 SAH 7.05128
264 3VC1 GST 7.05128
265 5OFW 9TW 7.17489
266 2VL1 GLY GLY 7.21154
267 5ERG SAM 7.31071
268 5YEC ATP 7.35294
269 3G2O SAM 7.35786
270 5M58 SAH 7.3913
271 5DM1 SAH 7.49064
272 5DM1 5D7 7.49064
273 1O94 ADP 7.57576
274 1BW9 NAD 7.58427
275 1C1X NAD 7.60563
276 5JE8 NAD 7.61589
277 5GWX SAR 7.74648
278 5GWX SAM 7.74648
279 1JQ3 AAT 7.77027
280 1G6H ADP 7.7821
281 5FA5 MTA 7.93269
282 4GQB 0XU 7.93269
283 1XCL SAH 8.08511
284 1HYH NAD 8.09062
285 5LD5 NAD 8.10056
286 5ZZ6 ADP 8.17308
287 5ZZ6 NAD 8.17308
288 5FTW SAH 8.20312
289 5N53 8NB 8.20513
290 5AHO TLA 8.33333
291 3OFK SAH 8.7963
292 1V59 NAD 8.89423
293 4M37 SAH 9.0379
294 4M38 SAH 9.0379
295 2IVD FAD 9.13461
296 3B1F NAD 9.31034
297 1Z3C SA8 9.39597
298 3TL1 JRO 9.43396
299 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 9.52381
300 5KOK SAH 9.57179
301 5KOK R9T 9.57179
302 5KOK S9T 9.57179
303 2AOT SAH 9.58904
304 1JQD SAH 9.58904
305 1JQD HSM 9.58904
306 1R18 SAH 9.69163
307 2YN4 39J 9.74576
308 1BC5 SAH 10.0372
309 4IF4 BEF 10.0962
310 5ZW3 SAH 10.2222
311 5W7M SAH 10.2564
312 5WP5 SAH 10.3365
313 5WP4 SAH 10.3365
314 2RGO FAD 10.3365
315 4ZGS NAD 10.3627
316 3LCC SAH 10.6383
317 5XLX SAH 10.6383
318 2PWY SAH 10.8527
319 2VDV SAM 10.9756
320 3JWH SAH 11.5207
321 2PXX SAH 11.6279
322 5X62 SAH 12.5616
323 1OMO NAD 12.7329
324 3H8V ATP 13.0137
325 4Y30 SAH 13.1054
326 4Y30 49L 13.1054
327 1DL5 SAH 13.2492
328 4II2 ATP 13.253
329 6GKV SAH 13.3903
330 4ODV GP1 Z9M 13.5135
331 3IWD M2T 14.5161
332 3GWZ SAH 14.6341
333 3GXO SAH 14.6341
334 5T9E NAP 14.7601
335 4QTU SAM 15.3846
336 4FZV SAM 15.4812
337 5IL1 SAM 15.566
338 2YX1 SFG 15.7738
339 1TLG GAL 16
340 1TPY SAH 16.3763
341 5FWA J7C 16.5865
342 1NVT NAP 16.7247
343 1VE3 SAM 16.7401
344 3GJ7 GDP 17.3469
345 1KPG SAH 17.4216
346 4R6W SAH 17.8295
347 4R6W PC 17.8295
348 3GJ4 GDP 18.1818
349 1NM5 NAD 18.2266
350 1KPH SAH 18.4669
351 4OBW SAM 18.677
352 5L95 AMP 18.75
353 4URG C2E 19.1617
354 1IM8 SAI 20.082
355 2AG8 NAP 20.1521
356 5DWQ SFG 20.9169
357 5DX1 SFG 20.9169
358 5DX8 SFG 20.9169
359 5DXA SFG 20.9169
360 5DX0 SFG 20.9169
361 6ARJ SAH 20.9169
362 6ARJ BW4 20.9169
363 4B5W PYR 21.875
364 3Q87 SAM 22.9412
365 3DUW SAH 24.6637
366 2NXE SAM 25.9843
367 3VPB GLU 26.7857
368 2HMT NAI 36.1111
Pocket No.: 3; Query (leader) PDB : 5T67; Ligand: JHZ; Similar sites found with APoc: 36
This union binding pocket(no: 3) in the query (biounit: 5t67.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
1 5KOR GDP 1.68269
2 3FU7 3DM 1.92308
3 4Z0H NAD 2.09581
4 4XFR CIT 2.40385
5 3S5W NAP 2.40385
6 1JJ7 ADP 2.69231
7 3KU0 ADE 2.78884
8 1M2K APR 2.81124
9 5EEH P9P 2.92553
10 2CBZ ATP 2.95359
11 5EWK P34 3
12 5TVF CGQ 3.52941
13 4LS3 HIS 3.60577
14 1I1N SAH 3.9823
15 4OKE AMP 4.16667
16 2QES ADE 4.21456
17 1I7M CG 4.47761
18 2QQF A1R 4.87013
19 1L5Y BEF 5.16129
20 5F7J ADE 5.625
21 2CZL TLA 5.88235
22 4HNN LYS 6.06936
23 4YUW 4JU 6.25
24 4YUW S4M 6.25
25 2RIF AMP 6.38298
26 3B12 FAH 6.57895
27 4JZ8 CIT 6.94006
28 1HSL HIS 7.14286
29 4AIA ADK 7.97872
30 2PZE ATP 8.29694
31 3WIR BGC 9.13461
32 3ZZQ TRP 9.23077
33 2V3V MGD 12.0192
34 5LNE A2G GAL 18.9024
35 4P83 U5P 20.8791
36 3RMK BML 28.9157
Pocket No.: 4; Query (leader) PDB : 5T67; Ligand: SAH; Similar sites found with APoc: 35
This union binding pocket(no: 4) in the query (biounit: 5t67.bio1) has 41 residues
No: Leader PDB Ligand Sequence Similarity
1 2VWA PTY None
2 1L7E NAI 1.30208
3 5KOR GDP 1.68269
4 3FU7 3DM 1.92308
5 4XFR CIT 2.40385
6 2WW5 CHT 2.40385
7 4U00 ADP 2.45902
8 5LE1 6UW 2.63158
9 1JJ7 ADP 2.69231
10 3KU0 ADE 2.78884
11 1M2K APR 2.81124
12 5EEH P9P 2.92553
13 4J51 N75 3.36538
14 2Z3U CRR 3.84615
15 5LX9 OLB 3.90879
16 1I1N SAH 3.9823
17 4X8D AVI 4.08654
18 2BGM MAX 4.31655
19 1JZN BGC GAL 4.44444
20 2QQF A1R 4.87013
21 2Q7V FAD 4.92308
22 2BZ1 TAU 5.10204
23 2RIF AMP 6.38298
24 3B12 FAH 6.57895
25 1T36 ORN 6.73077
26 1HSL HIS 7.14286
27 4M52 FAD 8.17308
28 2PZE ATP 8.29694
29 1XVB BHL BHL 8.89423
30 2YN4 39J 9.74576
31 4A7W GTP 11.25
32 2V3V MGD 12.0192
33 1NVT NAP 16.7247
34 5LNE A2G GAL 18.9024
35 4P83 U5P 20.8791
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