Receptor
PDB id Resolution Class Description Source Keywords
5OMR 1.68 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF AMYCOLATOPSIS CYTOCHROME P450 GCOA IN C WITH VANILLIN. AMYCOLATOPSIS SP. ATCC 39116 CYTOCHROME P450 GUAIACOL LIGNIN CYP255A AMYCOLATOPSIS HAEM OXIDOREDUCTASE VANILLIN
Ref.: A PROMISCUOUS CYTOCHROME P450 AROMATIC O-DEMETHYLAS LIGNIN BIOCONVERSION. NAT COMMUN V. 9 2487 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HEM A:501;
 Part of Protein;
 none;
 submit data
616.487 C34 H32 Fe N4 O4 Cc1c2...
V55 A:502;
 Valid;
 none;
 submit data
152.147 C8 H8 O3 COc1c...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6HQQ 1.66 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF GCOA F169A BOUND TO SYRINGOL AMYCOLATOPSIS SP. ATCC 39116 CYTOCHROME P450 LIGNIN. OXIDOREDUCTASE
Ref.: ENABLING MICROBIAL SYRINGOL CONVERSION THROUGH STRUCTURE-GUIDED PROTEIN ENGINEERING. PROC.NATL.ACAD.SCI.USA V. 116 13970 2019
Members (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 5OMS - 261 C8 H10 O2 CCOc1ccccc....
2 5OMR - V55 C8 H8 O3 COc1cc(ccc....
3 6HQN - JZ3 C7 H8 O2 COc1ccccc1....
4 6HQM - JZ3 C7 H8 O2 COc1ccccc1....
5 6HQS - 3DM C8 H10 O3 COc1cccc(c....
6 6HQL - JZ3 C7 H8 O2 COc1ccccc1....
7 6HQP - JZ3 C7 H8 O2 COc1ccccc1....
8 6HQK Kd = 7.1 uM JZ3 C7 H8 O2 COc1ccccc1....
9 5OMU - 3DM C8 H10 O3 COc1cccc(c....
10 6HQR - 3DM C8 H10 O3 COc1cccc(c....
11 5NCB - JZ3 C7 H8 O2 COc1ccccc1....
12 6HQT - 3DM C8 H10 O3 COc1cccc(c....
13 6HQQ Kd = 1.7 uM 3DM C8 H10 O3 COc1cccc(c....
14 6HQO - JZ3 C7 H8 O2 COc1ccccc1....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 5OMS - 261 C8 H10 O2 CCOc1ccccc....
2 5OMR - V55 C8 H8 O3 COc1cc(ccc....
3 6HQN - JZ3 C7 H8 O2 COc1ccccc1....
4 6HQM - JZ3 C7 H8 O2 COc1ccccc1....
5 6HQS - 3DM C8 H10 O3 COc1cccc(c....
6 6HQL - JZ3 C7 H8 O2 COc1ccccc1....
7 6HQP - JZ3 C7 H8 O2 COc1ccccc1....
8 6HQK Kd = 7.1 uM JZ3 C7 H8 O2 COc1ccccc1....
9 5OMU - 3DM C8 H10 O3 COc1cccc(c....
10 6HQR - 3DM C8 H10 O3 COc1cccc(c....
11 5NCB - JZ3 C7 H8 O2 COc1ccccc1....
12 6HQT - 3DM C8 H10 O3 COc1cccc(c....
13 6HQQ Kd = 1.7 uM 3DM C8 H10 O3 COc1cccc(c....
14 6HQO - JZ3 C7 H8 O2 COc1ccccc1....
50% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 5OMS - 261 C8 H10 O2 CCOc1ccccc....
2 5OMR - V55 C8 H8 O3 COc1cc(ccc....
3 6HQN - JZ3 C7 H8 O2 COc1ccccc1....
4 6HQM - JZ3 C7 H8 O2 COc1ccccc1....
5 6HQS - 3DM C8 H10 O3 COc1cccc(c....
6 6HQL - JZ3 C7 H8 O2 COc1ccccc1....
7 6HQP - JZ3 C7 H8 O2 COc1ccccc1....
8 6HQK Kd = 7.1 uM JZ3 C7 H8 O2 COc1ccccc1....
9 5OMU - 3DM C8 H10 O3 COc1cccc(c....
10 6HQR - 3DM C8 H10 O3 COc1cccc(c....
11 5NCB - JZ3 C7 H8 O2 COc1ccccc1....
12 6HQT - 3DM C8 H10 O3 COc1cccc(c....
13 6HQQ Kd = 1.7 uM 3DM C8 H10 O3 COc1cccc(c....
14 6HQO - JZ3 C7 H8 O2 COc1ccccc1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: V55; Similar ligands found: 13
No: Ligand ECFP6 Tc MDL keys Tc
1 V55 1 1
2 CIY 0.595238 0.952381
3 4M4 0.589744 0.818182
4 EUG 0.575 0.818182
5 H7Y 0.575 0.818182
6 GJK 0.533333 0.909091
7 FER 0.533333 0.833333
8 C9M 0.521739 0.678571
9 N7I 0.511111 0.703704
10 ZYC 0.45283 0.689655
11 3Z7 0.45 0.75
12 CUR 0.428571 0.689655
13 F0J 0.414634 0.826087
Similar Ligands (3D)
Ligand no: 1; Ligand: V55; Similar ligands found: 1322
No: Ligand Similarity coefficient
1 4HM 0.9968
2 VNL 0.9773
3 VOH 0.9763
4 EOL 0.9717
5 AEH 0.9709
6 KOJ 0.9689
7 HX3 0.9663
8 BGC 0.9660
9 6LW 0.9656
10 4ZC 0.9650
11 AH8 0.9640
12 GCS 0.9637
13 6CS 0.9616
14 F31 0.9608
15 G4D 0.9598
16 R8S 0.9597
17 AHR 0.9591
18 G3F 0.9590
19 Q88 0.9588
20 8S0 0.9587
21 GLC 0.9583
22 DNF 0.9579
23 3DO 0.9575
24 3R6 0.9573
25 GAL 0.9565
26 5MK 0.9564
27 CWM 0.9563
28 ASO 0.9557
29 ES0 0.9553
30 5M0 0.9547
31 54G 0.9541
32 1DW 0.9538
33 4XR 0.9536
34 GTQ 0.9534
35 FRU 0.9520
36 II6 0.9517
37 2D0 0.9515
38 XX2 0.9512
39 TWO 0.9512
40 DHB 0.9510
41 CHB 0.9509
42 P9P 0.9507
43 5RG 0.9506
44 KT7 0.9505
45 3MB 0.9504
46 FOT 0.9499
47 3MG 0.9497
48 9TZ 0.9496
49 1P7 0.9495
50 SX1 0.9494
51 LDP 0.9494
52 4NC 0.9494
53 QSB 0.9494
54 DIG 0.9493
55 DGJ 0.9493
56 OW4 0.9490
57 7WR 0.9486
58 LGC 0.9486
59 MBG 0.9480
60 2A9 0.9476
61 RM1 0.9469
62 CWS 0.9468
63 URC 0.9467
64 UNC 0.9466
65 OVM 0.9462
66 9TW 0.9462
67 KBG 0.9459
68 IJZ 0.9458
69 FHB 0.9458
70 JND 0.9458
71 IFL 0.9457
72 8WT 0.9456
73 DHK 0.9454
74 2HO 0.9453
75 93K 0.9451
76 VXX 0.9450
77 HJP 0.9448
78 INO 0.9448
79 MYJ 0.9447
80 8CM 0.9446
81 0P6 0.9446
82 3XX 0.9446
83 7VJ 0.9444
84 LCN 0.9444
85 3Z8 0.9439
86 JLZ 0.9438
87 5JC 0.9437
88 IHB 0.9436
89 5B1 0.9434
90 NOJ 0.9434
91 2MN 0.9433
92 G2F 0.9432
93 S76 0.9431
94 KUF 0.9427
95 4A3 0.9426
96 NOY 0.9422
97 4CS 0.9422
98 MZG 0.9421
99 2XX 0.9421
100 JFJ 0.9420
101 4XV 0.9419
102 Y8I 0.9417
103 7VS 0.9416
104 94B 0.9416
105 MWJ 0.9416
106 IF7 0.9416
107 2FG 0.9410
108 HLZ 0.9408
109 QOS 0.9408
110 GYE 0.9405
111 0W8 0.9404
112 3HM 0.9404
113 27Y 0.9403
114 12M 0.9403
115 XQG 0.9403
116 I3A 0.9402
117 JZ2 0.9399
118 4JJ 0.9397
119 URF 0.9396
120 HT4 0.9394
121 42A 0.9394
122 PDC 0.9393
123 XBZ 0.9392
124 A1U 0.9392
125 2AC 0.9390
126 BMA 0.9389
127 OMD 0.9389
128 4CL 0.9388
129 9MG 0.9386
130 NNO 0.9384
131 C2U 0.9381
132 MCT 0.9381
133 2EC 0.9381
134 8TX 0.9381
135 4AV 0.9380
136 SRO 0.9379
137 DIE 0.9378
138 B55 0.9378
139 NMJ 0.9378
140 2YU 0.9377
141 PYD 0.9377
142 4ZE 0.9376
143 34A 0.9376
144 BR9 0.9375
145 N8Y 0.9374
146 GOX 0.9374
147 AS3 0.9374
148 3OC 0.9372
149 TM7 0.9371
150 4XS 0.9370
151 43M 0.9370
152 HHA 0.9369
153 LZM 0.9369
154 2MP 0.9367
155 XYD 0.9367
156 AX3 0.9367
157 ALL 0.9365
158 GIV 0.9365
159 7HQ 0.9364
160 XAZ 0.9363
161 149 0.9360
162 MWM 0.9360
163 42J 0.9359
164 MWP 0.9359
165 OVP 0.9358
166 UAN 0.9357
167 EV0 0.9357
168 OW7 0.9350
169 IFM 0.9348
170 75K 0.9348
171 A7W 0.9347
172 SOR 0.9339
173 2H5 0.9339
174 M0Q 0.9338
175 WOO 0.9338
176 ZWZ 0.9337
177 BZ3 0.9335
178 XYL 0.9334
179 RB5 0.9334
180 948 0.9331
181 3HB 0.9330
182 FX1 0.9328
183 DIN 0.9327
184 GXY 0.9326
185 TLD 0.9326
186 QBK 0.9326
187 B62 0.9325
188 PXL 0.9324
189 WBU 0.9323
190 8IG 0.9323
191 FE DB1 0.9322
192 5XC 0.9322
193 NGO 0.9322
194 BTY 0.9322
195 DBJ 0.9318
196 LFR 0.9318
197 PRZ 0.9317
198 ICP 0.9316
199 8WO 0.9314
200 P3K 0.9313
201 4HO 0.9312
202 5MH 0.9311
203 NDM 0.9311
204 1SQ 0.9306
205 TH0 0.9305
206 XX3 0.9304
207 ZZ3 0.9303
208 1GN 0.9303
209 GDE 0.9302
210 82I 0.9302
211 M1E 0.9301
212 T6C 0.9301
213 1LM 0.9298
214 GLT 0.9297
215 GLA 0.9297
216 MRW 0.9296
217 OVV 0.9296
218 463 0.9295
219 OTW 0.9294
220 HH8 0.9294
221 SKM 0.9294
222 KIB 0.9291
223 7MU 0.9290
224 SWD 0.9288
225 7MH 0.9287
226 XLS 0.9286
227 2A7 0.9286
228 C2A 0.9286
229 ZZT 0.9285
230 DBH 0.9285
231 OXZ 0.9284
232 ES1 0.9283
233 LYL 0.9283
234 3HA 0.9283
235 SHG 0.9282
236 BTE 0.9282
237 WCE 0.9281
238 4XH 0.9280
239 8ZE 0.9280
240 DNC 0.9278
241 5OB 0.9278
242 ADZ 0.9277
243 5JL 0.9277
244 23A 0.9277
245 ORO 0.9277
246 5WY 0.9277
247 86J 0.9276
248 9DG 0.9276
249 GXL 0.9275
250 GAB 0.9275
251 7NI 0.9274
252 FP1 0.9274
253 5IQ 0.9274
254 25W 0.9274
255 JBH 0.9273
256 TDR 0.9273
257 AKH 0.9272
258 JBK 0.9272
259 1NP 0.9272
260 BK9 0.9271
261 24W 0.9271
262 M0W 0.9270
263 JIF 0.9268
264 Q6T 0.9267
265 FUL 0.9266
266 SOE 0.9266
267 QSH 0.9266
268 1MC 0.9265
269 BDP 0.9264
270 1LQ 0.9263
271 5SG 0.9263
272 069 0.9263
273 HMH 0.9263
274 3NT 0.9262
275 3F0 0.9261
276 E7Z 0.9261
277 3AB 0.9261
278 G6D 0.9260
279 JPZ 0.9259
280 BSX 0.9258
281 HA5 0.9258
282 PZI 0.9258
283 5Q0 0.9256
284 CN0 0.9256
285 HPA 0.9255
286 275 0.9254
287 XYP 0.9254
288 M1H 0.9252
289 3M0 0.9251
290 N5J 0.9250
291 3BZ 0.9250
292 RIB 0.9249
293 4YS 0.9249
294 DQU 0.9249
295 5RO 0.9249
296 YIO 0.9248
297 GLF 0.9248
298 7B4 0.9248
299 BRT 0.9248
300 FGZ 0.9247
301 XHP 0.9247
302 RD4 0.9247
303 4ME 0.9247
304 3DM 0.9245
305 3ID 0.9245
306 ICO 0.9245
307 1U6 0.9245
308 ESI 0.9244
309 44V 0.9243
310 2AL 0.9242
311 8GC 0.9240
312 SF9 0.9239
313 4JO 0.9237
314 5JQ 0.9237
315 MR1 0.9236
316 PD2 0.9236
317 KIA 0.9235
318 AMG 0.9233
319 K3Q 0.9233
320 6MP 0.9233
321 DOR 0.9232
322 35C 0.9231
323 SWA 0.9231
324 GUN 0.9231
325 X6X 0.9230
326 5UC 0.9229
327 42C 0.9229
328 LXC 0.9228
329 B60 0.9227
330 AW5 0.9227
331 HQY 0.9227
332 MAN 0.9227
333 XXR 0.9227
334 9FE 0.9226
335 AGK 0.9225
336 GIF 0.9224
337 X0V 0.9224
338 KKN 0.9223
339 GTL 0.9223
340 7ME 0.9223
341 53C 0.9223
342 ES4 0.9223
343 QX4 0.9222
344 XUL 0.9222
345 AZA 0.9221
346 M1A 0.9220
347 NFQ 0.9219
348 GAF 0.9219
349 10L 0.9217
350 FHN 0.9215
351 6ME 0.9215
352 AJ2 0.9215
353 XQ0 0.9214
354 ES7 0.9213
355 261 0.9213
356 HQT 0.9212
357 ADE 0.9212
358 B53 0.9211
359 DMJ 0.9210
360 SHA 0.9208
361 SF6 0.9208
362 JFD 0.9206
363 GCU 0.9206
364 0W1 0.9206
365 UEG 0.9205
366 A65 0.9204
367 O72 0.9203
368 0HN 0.9203
369 RNT 0.9203
370 67N 0.9202
371 8G0 0.9202
372 OXC 0.9202
373 GV9 0.9201
374 24B 0.9201
375 IV2 0.9199
376 ZB1 0.9199
377 D1X 0.9199
378 DHS 0.9198
379 YTX 0.9198
380 CFP 0.9198
381 F12 0.9197
382 TBP 0.9196
383 DIU 0.9195
384 44W 0.9193
385 5RN 0.9193
386 7HP 0.9191
387 ZXD 0.9191
388 KTA 0.9190
389 F4Z 0.9189
390 HMU 0.9189
391 HXX 0.9189
392 4Z4 0.9188
393 34D 0.9188
394 BCU 0.9188
395 4MU 0.9188
396 9DA 0.9188
397 GZL 0.9186
398 FUC 0.9185
399 MAQ 0.9185
400 XAN 0.9185
401 4HC 0.9183
402 5HN 0.9183
403 JAE 0.9183
404 M6N 0.9182
405 H76 0.9181
406 BZX 0.9181
407 9HX 0.9181
408 FYU 0.9181
409 PM6 0.9180
410 MVN 0.9180
411 ASC 0.9180
412 RNS 0.9180
413 ADK 0.9180
414 4A5 0.9179
415 0FO 0.9179
416 2CQ 0.9179
417 ES5 0.9179
418 FDK 0.9178
419 JB5 0.9178
420 PA1 0.9177
421 PXM 0.9177
422 M5K 0.9177
423 NSP 0.9177
424 SYV 0.9176
425 Q24 0.9175
426 FH2 0.9175
427 BCP 0.9175
428 LNR 0.9174
429 141 0.9174
430 0HO 0.9173
431 KTW 0.9172
432 NTZ 0.9171
433 A29 0.9171
434 APZ 0.9170
435 KJY 0.9170
436 R2B 0.9170
437 4FS 0.9170
438 DMD 0.9170
439 2HQ 0.9168
440 G5V 0.9168
441 5WX 0.9168
442 F5B 0.9167
443 JZ3 0.9167
444 7WA 0.9166
445 BEA 0.9166
446 8XQ 0.9166
447 4AA 0.9164
448 ABV 0.9164
449 1AL 0.9162
450 KBB 0.9162
451 TC7 0.9160
452 5QX 0.9160
453 DX4 0.9159
454 0CU 0.9157
455 L99 0.9157
456 BP1 0.9156
457 N2I 0.9156
458 IGA 0.9154
459 MO8 0.9153
460 HNQ 0.9153
461 1WG 0.9152
462 EYK 0.9152
463 ISN 0.9151
464 15L 0.9150
465 2LP 0.9150
466 F9Y 0.9150
467 LRH 0.9149
468 717 0.9149
469 XIY 0.9149
470 45C 0.9148
471 12Q 0.9147
472 SKA 0.9147
473 PE0 0.9147
474 680 0.9147
475 COU 0.9146
476 92K 0.9145
477 150 0.9144
478 MFB 0.9144
479 TSS 0.9144
480 ES9 0.9144
481 6R8 0.9144
482 03V 0.9143
483 290 0.9143
484 KJU 0.9142
485 AZ8 0.9142
486 ADA 0.9141
487 TH7 0.9138
488 FA1 0.9138
489 H42 0.9138
490 H4N 0.9138
491 2BG 0.9137
492 B2J 0.9136
493 RJY 0.9136
494 7W4 0.9135
495 MEW 0.9135
496 1X7 0.9135
497 OCH 0.9134
498 2AQ 0.9133
499 1F1 0.9133
500 GT0 0.9131
501 ABE 0.9131
502 FUD 0.9131
503 3MA 0.9131
504 2DR 0.9131
505 KJH 0.9130
506 8H8 0.9130
507 2FY 0.9129
508 NIZ 0.9129
509 4SX 0.9128
510 11S 0.9128
511 M1Q 0.9127
512 4FH 0.9127
513 3A9 0.9126
514 AQO 0.9126
515 JTH 0.9126
516 IUR 0.9125
517 5WV 0.9125
518 DEE 0.9125
519 DBX 0.9125
520 GLY PRO 0.9125
521 5MB 0.9124
522 6RQ 0.9124
523 GTR 0.9124
524 R8V 0.9123
525 FCA 0.9122
526 6AI 0.9121
527 AX7 0.9121
528 SJ5 0.9120
529 P92 0.9119
530 R9Y 0.9118
531 1M2 0.9118
532 BOA 0.9118
533 FA6 0.9117
534 EVA 0.9117
535 Z6J 0.9114
536 FDB 0.9114
537 GCB 0.9114
538 LT2 0.9113
539 2MI 0.9113
540 14O 0.9112
541 5MI 0.9111
542 FPY 0.9110
543 6GU 0.9110
544 GIO 0.9110
545 EMZ 0.9109
546 DRL 0.9109
547 J9W 0.9108
548 5H1 0.9108
549 0RW 0.9107
550 MNM 0.9107
551 KDV 0.9106
552 2ZM 0.9106
553 0MK 0.9105
554 LKA 0.9105
555 AIN 0.9104
556 F05 0.9104
557 SXS 0.9102
558 IFP 0.9102
559 DFU 0.9101
560 CKU 0.9101
561 6M4 0.9101
562 ONR 0.9101
563 7W1 0.9100
564 AFR 0.9100
565 X0W 0.9099
566 495 0.9098
567 6AP 0.9098
568 HH5 0.9098
569 0LH 0.9097
570 MT0 0.9096
571 3NY 0.9096
572 GJS 0.9094
573 TTL 0.9094
574 HQJ 0.9094
575 3IT 0.9094
576 FK1 0.9093
577 SAL 0.9093
578 EA1 0.9092
579 PFB 0.9092
580 5WU 0.9091
581 NCD 0.9091
582 7ZE 0.9090
583 F81 0.9090
584 GM7 0.9089
585 QAT 0.9089
586 EKZ 0.9088
587 M2H 0.9088
588 6NT 0.9088
589 1XM 0.9086
590 YH7 0.9086
591 DFB 0.9086
592 RXA 0.9086
593 6M9 0.9085
594 1XN 0.9085
595 HZQ 0.9084
596 5NU 0.9084
597 ABI 0.9084
598 0R0 0.9084
599 RIP 0.9083
600 270 0.9083
601 TTY 0.9078
602 IPZ 0.9078
603 A2F 0.9078
604 4JT 0.9077
605 ISD 0.9076
606 FUF 0.9075
607 HQD 0.9074
608 1P3 0.9073
609 AZF 0.9073
610 F60 0.9073
611 0F9 0.9073
612 D48 0.9072
613 9EW 0.9071
614 DHQ 0.9069
615 BHO 0.9069
616 B57 0.9068
617 SVN 0.9068
618 2ZQ 0.9067
619 GZ8 0.9066
620 CXF 0.9066
621 0JD 0.9065
622 8HC 0.9064
623 G3E 0.9064
624 UFO 0.9063
625 MFU 0.9061
626 32X 0.9060
627 3RK 0.9060
628 QDK 0.9059
629 0FK 0.9058
630 O2A 0.9058
631 SVD 0.9057
632 RM4 0.9055
633 2K4 0.9055
634 AZ9 0.9054
635 NQ 0.9054
636 5CU 0.9053
637 B3R 0.9053
638 RAM 0.9053
639 DOB 0.9051
640 PSV 0.9051
641 YSO 0.9051
642 2HU 0.9050
643 ISZ 0.9050
644 SE2 0.9049
645 L3Q 0.9047
646 MUA 0.9047
647 15N 0.9046
648 MB1 0.9044
649 BHA 0.9043
650 BE2 0.9043
651 TSR 0.9041
652 CRS 0.9040
653 IDH 0.9039
654 JZ4 0.9039
655 HIS 0.9039
656 TFU 0.9038
657 M2K 0.9038
658 YQA 0.9037
659 9ZE 0.9037
660 4TU 0.9037
661 HHR 0.9036
662 AZG 0.9036
663 8NY 0.9036
664 FCB 0.9035
665 2GS 0.9034
666 5GU 0.9034
667 ZZZ 0.9033
668 PRY 0.9033
669 FA0 0.9031
670 SR1 0.9031
671 JAW 0.9031
672 J5I 0.9029
673 QAS 0.9027
674 VK3 0.9027
675 3U4 0.9026
676 PRF 0.9026
677 12B 0.9026
678 H6B 0.9025
679 PH2 0.9025
680 M3T 0.9024
681 HEW 0.9024
682 4H2 0.9023
683 CWJ 0.9022
684 EQT 0.9022
685 NK 0.9021
686 TRC 0.9021
687 JA8 0.9020
688 OAA 0.9019
689 0N7 0.9018
690 L5V 0.9018
691 HBA 0.9018
692 5NI 0.9017
693 JXN 0.9016
694 QIC 0.9015
695 QPR 0.9014
696 PEA 0.9014
697 AJV 0.9013
698 AJY 0.9012
699 VNJ 0.9008
700 9KH 0.9007
701 EJZ 0.9006
702 ES2 0.9005
703 CFI 0.9005
704 4M0 0.9004
705 AY4 0.9003
706 DPZ 0.9002
707 HGQ 0.9002
708 2AK 0.9000
709 GTZ 0.9000
710 284 0.8999
711 MXN 0.8998
712 3PF 0.8998
713 D07 0.8997
714 AL0 0.8997
715 XYS 0.8997
716 EXO 0.8996
717 FAN 0.8995
718 NVU 0.8993
719 MA3 0.8992
720 JDN 0.8992
721 CBF 0.8991
722 DQA 0.8991
723 ET2 0.8991
724 DHY 0.8990
725 329 0.8990
726 KDF 0.8988
727 SYA 0.8987
728 2LY 0.8986
729 GLO 0.8986
730 HPT 0.8983
731 MSN 0.8982
732 51R 0.8981
733 1P8 0.8981
734 RCO 0.8977
735 URA 0.8977
736 6VD 0.8975
737 ES6 0.8974
738 CTL 0.8973
739 5QY 0.8973
740 FBM 0.8972
741 209 0.8972
742 3CH 0.8972
743 UFV 0.8972
744 C2Y 0.8971
745 8NX 0.8971
746 FA3 0.8971
747 OA3 0.8970
748 92P 0.8969
749 GLY CYS 0.8969
750 PHB 0.8969
751 NBG 0.8968
752 1PT 0.8967
753 26D 0.8967
754 8VN 0.8966
755 SLS 0.8966
756 1KP 0.8966
757 4SV 0.8966
758 NDH 0.8964
759 95Z 0.8964
760 HLD 0.8963
761 0GZ 0.8963
762 HHQ 0.8963
763 IPB 0.8960
764 3BU 0.8960
765 4P5 0.8960
766 5CL 0.8959
767 JKE 0.8958
768 VGD 0.8956
769 X09 0.8955
770 J9T 0.8955
771 7D2 0.8954
772 NID 0.8954
773 TEP 0.8954
774 2O6 0.8953
775 URQ 0.8953
776 DTL 0.8952
777 CIG 0.8952
778 TIU 0.8952
779 NPO 0.8951
780 7I2 0.8951
781 RAT 0.8951
782 5VM 0.8950
783 KYA 0.8950
784 TZE 0.8948
785 IAC 0.8947
786 CLW 0.8945
787 1WD 0.8945
788 OTD 0.8944
789 LG5 0.8944
790 GYP 0.8943
791 E1T 0.8943
792 B5D 0.8942
793 CTS 0.8942
794 H33 0.8942
795 4VY 0.8942
796 XM0 0.8941
797 4FA 0.8940
798 6NI 0.8939
799 ESP 0.8939
800 JUG 0.8939
801 8W9 0.8939
802 FBB 0.8936
803 ODO 0.8936
804 FBW 0.8935
805 3C4 0.8935
806 INE 0.8934
807 PKU 0.8934
808 36R 0.8933
809 PQK 0.8933
810 R9S 0.8931
811 4VP 0.8931
812 J9Q 0.8930
813 M5N 0.8929
814 EXD 0.8927
815 LG3 0.8927
816 5ZE 0.8927
817 K2T 0.8926
818 BVF 0.8925
819 47J 0.8924
820 091 0.8924
821 XCZ 0.8923
822 I1E 0.8923
823 JBE 0.8922
824 V6F 0.8920
825 A13 0.8919
826 BDF 0.8919
827 E35 0.8918
828 PAC 0.8918
829 C9E 0.8917
830 F9P 0.8915
831 PAB 0.8915
832 EDR 0.8913
833 PYQ 0.8913
834 KP6 0.8911
835 293 0.8911
836 TAG 0.8910
837 BZ2 0.8910
838 Q71 0.8909
839 4JQ 0.8908
840 YRL 0.8907
841 IOS 0.8907
842 APS 0.8905
843 HY1 0.8904
844 INS 0.8902
845 DA4 0.8902
846 1XX 0.8901
847 61M 0.8900
848 9KT 0.8900
849 Z5P 0.8896
850 7N0 0.8895
851 PQ0 0.8895
852 KYD 0.8895
853 LMR 0.8895
854 6M1 0.8894
855 PHU 0.8893
856 5NE 0.8892
857 H8N 0.8892
858 HBD 0.8892
859 X05 0.8891
860 CYT 0.8891
861 14J 0.8891
862 BEZ 0.8890
863 286 0.8889
864 RSO 0.8889
865 JF2 0.8888
866 4ZA 0.8885
867 M1Z 0.8885
868 ISE 0.8885
869 3AL 0.8884
870 692 0.8882
871 FDR 0.8881
872 268 0.8881
873 GNL 0.8880
874 13X 0.8880
875 4JL 0.8880
876 RSF 0.8879
877 MMA 0.8878
878 2EH 0.8878
879 JF1 0.8878
880 R8A 0.8877
881 MQN 0.8876
882 AC6 0.8876
883 ARB 0.8876
884 97T 0.8876
885 8GF 0.8876
886 C2B 0.8876
887 AMC 0.8875
888 GHM 0.8874
889 G1O 0.8874
890 5AN 0.8874
891 3FH 0.8873
892 3WA 0.8872
893 8VE 0.8869
894 4KL 0.8869
895 HQ9 0.8869
896 MS9 0.8868
897 6FZ 0.8867
898 GRE 0.8866
899 FBA 0.8865
900 XXG 0.8865
901 2ZX 0.8865
902 3SK 0.8865
903 TCZ 0.8863
904 FPK 0.8861
905 CLZ 0.8861
906 39A 0.8860
907 JB8 0.8860
908 2TQ 0.8860
909 7B3 0.8859
910 GLU 0.8859
911 SFU 0.8857
912 BNF 0.8857
913 6DP 0.8856
914 M4T 0.8856
915 P72 0.8856
916 NLA 0.8855
917 ORN 0.8854
918 2SX 0.8854
919 AX2 0.8854
920 94W 0.8852
921 ERH 0.8852
922 JZ1 0.8851
923 6UA 0.8851
924 AEF 0.8850
925 FIX 0.8850
926 K5W 0.8850
927 ZYR 0.8849
928 R1X 0.8848
929 PBZ 0.8848
930 K22 0.8848
931 6F0 0.8848
932 FBU 0.8845
933 3HP 0.8845
934 MQB 0.8844
935 4YO 0.8844
936 57O 0.8843
937 BZJ 0.8842
938 4MA 0.8841
939 3R9 0.8840
940 2FQ 0.8839
941 PEL 0.8839
942 6PC 0.8838
943 BR8 0.8838
944 23J 0.8838
945 9X7 0.8837
946 E7S 0.8837
947 9PY 0.8836
948 258 0.8835
949 4WL 0.8835
950 QUZ 0.8834
951 1Y6 0.8833
952 6MH 0.8832
953 DUB 0.8832
954 P84 0.8831
955 15E 0.8831
956 9FL 0.8830
957 FPI 0.8828
958 3SL 0.8827
959 LI6 0.8826
960 0FN 0.8825
961 ICT 0.8825
962 DHR 0.8825
963 7WV 0.8825
964 Z82 0.8824
965 3AY 0.8822
966 826 0.8819
967 NEQ 0.8819
968 BEN 0.8818
969 NIG 0.8817
970 4XY 0.8816
971 ZVO 0.8816
972 PEY 0.8816
973 MLT 0.8814
974 12T 0.8813
975 LYS 0.8812
976 8NB 0.8811
977 ICB 0.8811
978 TOF 0.8810
979 R20 0.8810
980 J6W 0.8810
981 YCP 0.8809
982 173 0.8808
983 NIO 0.8807
984 HKD 0.8806
985 7WG 0.8806
986 8OZ 0.8806
987 CFF 0.8806
988 NPY 0.8805
989 0TU 0.8804
990 SC2 0.8804
991 9CA 0.8803
992 3CE 0.8802
993 GJZ 0.8802
994 XQK 0.8800
995 MNP 0.8800
996 6TZ 0.8800
997 GCO 0.8799
998 4JM 0.8798
999 VPR 0.8798
1000 LSA 0.8798
1001 SG2 0.8796
1002 MJ2 0.8796
1003 MET 0.8796
1004 94N 0.8793
1005 5OF 0.8793
1006 39U 0.8793
1007 JKZ 0.8792
1008 CIT 0.8792
1009 PCA 0.8790
1010 GOO 0.8789
1011 2CK 0.8788
1012 2CM 0.8788
1013 4VS 0.8785
1014 SRT 0.8785
1015 1IT 0.8785
1016 7CZ 0.8785
1017 2MY 0.8785
1018 2ZV 0.8785
1019 23W 0.8784
1020 TM4 0.8784
1021 MHK 0.8783
1022 KG1 0.8783
1023 8XL 0.8783
1024 F2W 0.8783
1025 GOG 0.8782
1026 TRA 0.8780
1027 20J 0.8780
1028 PFL 0.8780
1029 52C 0.8779
1030 SYN 0.8779
1031 ARP 0.8778
1032 32O 0.8778
1033 KMT 0.8778
1034 ASN 0.8778
1035 EN1 0.8777
1036 DZX 0.8775
1037 AOR 0.8775
1038 TAR 0.8775
1039 NPA 0.8775
1040 QBM 0.8773
1041 RPQ 0.8772
1042 3C1 0.8772
1043 NBZ 0.8772
1044 TGX 0.8771
1045 IBF 0.8771
1046 6XI 0.8771
1047 JG8 0.8771
1048 TPA 0.8771
1049 9R5 0.8770
1050 FLV 0.8769
1051 GF4 0.8769
1052 282 0.8769
1053 FQI 0.8769
1054 WDL 0.8768
1055 FBG 0.8767
1056 QXW 0.8767
1057 ABN 0.8767
1058 MVL 0.8766
1059 OKM 0.8766
1060 PHT 0.8766
1061 174 0.8765
1062 54D 0.8765
1063 226 0.8765
1064 3C2 0.8764
1065 H62 0.8764
1066 JBQ 0.8764
1067 NCA 0.8764
1068 2HC 0.8763
1069 JP2 0.8763
1070 HBX 0.8763
1071 PYG 0.8762
1072 ALA PRO 0.8760
1073 IP0 0.8760
1074 2K8 0.8759
1075 FLC 0.8759
1076 JR2 0.8759
1077 9YL 0.8759
1078 BCF 0.8758
1079 DQN 0.8757
1080 BBF 0.8756
1081 N3W 0.8756
1082 ESX 0.8756
1083 QWN 0.8756
1084 8GK 0.8756
1085 BPU 0.8755
1086 8U3 0.8753
1087 JXW 0.8752
1088 2D3 0.8752
1089 LDR 0.8752
1090 NTM 0.8750
1091 PY7 0.8750
1092 HPY 0.8750
1093 9CL 0.8749
1094 HSE 0.8749
1095 GBD 0.8748
1096 HTP 0.8748
1097 6OT 0.8748
1098 BAM 0.8747
1099 HA7 0.8746
1100 OXQ 0.8746
1101 HIO 0.8745
1102 NYL 0.8745
1103 K32 0.8743
1104 PYF 0.8743
1105 0TR 0.8743
1106 K97 0.8743
1107 PHE 0.8741
1108 PX7 0.8740
1109 MBD 0.8740
1110 HLR 0.8740
1111 NDG 0.8740
1112 IPT 0.8739
1113 AC0 0.8739
1114 FSW 0.8738
1115 AUD 0.8738
1116 I6G 0.8737
1117 PBC 0.8737
1118 PBA 0.8730
1119 OHP 0.8730
1120 PZA 0.8730
1121 ALE 0.8729
1122 9AP 0.8728
1123 MAJ 0.8727
1124 0XT 0.8726
1125 FXH 0.8724
1126 RMN 0.8724
1127 37T 0.8724
1128 E5X 0.8724
1129 DEN 0.8723
1130 GMN 0.8723
1131 QY9 0.8722
1132 FBV 0.8721
1133 JXZ 0.8721
1134 SW7 0.8720
1135 2PG 0.8719
1136 SMN 0.8716
1137 JU2 0.8716
1138 XBT 0.8715
1139 1MR 0.8715
1140 BZF 0.8715
1141 MZB 0.8714
1142 4SD 0.8714
1143 VGL 0.8713
1144 28N 0.8712
1145 TLA 0.8712
1146 GIM 0.8710
1147 260 0.8709
1148 67X 0.8709
1149 2C9 0.8708
1150 9RW 0.8707
1151 DEW 0.8705
1152 LPK 0.8704
1153 QSC 0.8703
1154 KLW 0.8702
1155 LDU 0.8700
1156 IND 0.8699
1157 XSP 0.8698
1158 MPV 0.8696
1159 PCI 0.8695
1160 ARW 0.8694
1161 3FA 0.8693
1162 BZI 0.8693
1163 X8D 0.8692
1164 ZBT 0.8691
1165 NAG 0.8691
1166 V1T 0.8691
1167 ENL 0.8689
1168 6BL 0.8689
1169 CFA 0.8689
1170 GAG 0.8688
1171 I2M 0.8688
1172 H3M 0.8688
1173 CSN 0.8688
1174 3MC 0.8687
1175 CXH 0.8686
1176 HHS 0.8686
1177 GVH 0.8685
1178 QBS 0.8685
1179 FB1 0.8684
1180 HHT 0.8683
1181 TBS 0.8683
1182 DUC 0.8682
1183 K17 0.8681
1184 6JN 0.8680
1185 6HQ 0.8680
1186 FK8 0.8679
1187 271 0.8679
1188 1A7 0.8679
1189 IDM 0.8679
1190 IBM 0.8678
1191 2CZ 0.8678
1192 XXP 0.8676
1193 NTN 0.8676
1194 RUU 0.8675
1195 SLC 0.8675
1196 M58 0.8673
1197 1LN 0.8672
1198 MYI 0.8670
1199 PYJ 0.8670
1200 LZ1 0.8669
1201 KDG 0.8668
1202 HFB 0.8668
1203 ASP 0.8668
1204 JZ9 0.8667
1205 Q7A 0.8667
1206 2MH 0.8667
1207 F3B 0.8662
1208 1U1 0.8662
1209 REL 0.8661
1210 BNT 0.8660
1211 TYL 0.8659
1212 IT2 0.8657
1213 HDH 0.8656
1214 FLM 0.8656
1215 CEE 0.8656
1216 UNU 0.8656
1217 MPI 0.8655
1218 60P 0.8653
1219 N8P 0.8653
1220 I1N 0.8653
1221 XEN 0.8652
1222 PZM 0.8648
1223 2CL 0.8647
1224 OTR 0.8647
1225 0R1 0.8646
1226 BNS 0.8645
1227 DYA 0.8641
1228 SS1 0.8641
1229 KFH 0.8640
1230 CGB 0.8639
1231 TEO 0.8638
1232 FFP 0.8636
1233 5NS 0.8636
1234 30G 0.8635
1235 GJP 0.8633
1236 PRA 0.8633
1237 BML 0.8632
1238 ANN 0.8631
1239 GVG 0.8629
1240 LZ2 0.8628
1241 2F6 0.8628
1242 QMS 0.8627
1243 0CT 0.8627
1244 2KA 0.8626
1245 428 0.8626
1246 SYR 0.8625
1247 3ZQ 0.8625
1248 OGA 0.8624
1249 152 0.8624
1250 4HS 0.8621
1251 W81 0.8620
1252 RHU 0.8619
1253 APY 0.8619
1254 PHH 0.8616
1255 1XA 0.8616
1256 R2P 0.8616
1257 4CH 0.8616
1258 40O 0.8615
1259 KGK 0.8612
1260 39O 0.8609
1261 SPD 0.8609
1262 64K 0.8608
1263 3MH 0.8605
1264 FBT 0.8603
1265 PAF 0.8602
1266 CH9 0.8601
1267 4JU 0.8600
1268 Q77 0.8599
1269 AKG 0.8598
1270 BEW 0.8597
1271 CAQ 0.8595
1272 4JN 0.8592
1273 OXE 0.8590
1274 PNZ 0.8586
1275 ARA 0.8586
1276 FF2 0.8585
1277 GLG 0.8582
1278 TT4 0.8580
1279 UNJ 0.8580
1280 SAN 0.8579
1281 PCR 0.8577
1282 G12 0.8576
1283 IOL 0.8575
1284 36E 0.8574
1285 2AF 0.8574
1286 6KT 0.8574
1287 FCR 0.8572
1288 27B 0.8572
1289 HQE 0.8571
1290 BPN 0.8569
1291 PXY 0.8567
1292 6X8 0.8565
1293 2CH 0.8565
1294 7MX 0.8564
1295 4BY 0.8564
1296 CIZ 0.8561
1297 GLN 0.8556
1298 PLQ 0.8555
1299 92Z 0.8555
1300 4NO 0.8553
1301 L7T 0.8552
1302 JZ0 0.8552
1303 QM1 0.8551
1304 25R 0.8550
1305 OK7 0.8549
1306 TSU 0.8548
1307 KPL 0.8547
1308 8LG 0.8543
1309 M5H 0.8541
1310 OHG 0.8538
1311 GNM 0.8537
1312 4BZ 0.8537
1313 L89 0.8536
1314 YTB 0.8536
1315 1L5 0.8536
1316 259 0.8536
1317 HSM 0.8535
1318 D3M 0.8533
1319 FP2 0.8525
1320 K34 0.8512
1321 938 0.8511
1322 AAS 0.8506
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6HQQ; Ligand: 3DM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6hqq.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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