Receptor
PDB id Resolution Class Description Source Keywords
5OCA 2.3 Å EC: 3.4.21.- PCSK9:FAB COMPLEX WITH DEXTRAN SULFATE HOMO SAPIENS HYDROLASE PROTEIN FAB COMPLEX AUTOCATALYTIC CLEAVAGE CHOLMETABOLISM DISEASE MUTATION DISULFIDE BOND GLYCOPROTEINMETABOLISM PHOSPHOPROTEIN PROTEASE SECRETED SERINE PROTSTEROID METABOLISM ZYMOGEN HYDROLASE-IMMUNE SYSTEM COMPLE
Ref.: HEPARAN SULFATE PROTEOGLYCANS PRESENT PCSK9 TO THE RECEPTOR. NAT COMMUN V. 8 503 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NA B:702;
B:701;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
TWD TWA C:1;
Valid;
Atoms found MORE than expected: % Diff = 2;
Kd = 180 uM
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5OCA 2.3 Å EC: 3.4.21.- PCSK9:FAB COMPLEX WITH DEXTRAN SULFATE HOMO SAPIENS HYDROLASE PROTEIN FAB COMPLEX AUTOCATALYTIC CLEAVAGE CHOLMETABOLISM DISEASE MUTATION DISULFIDE BOND GLYCOPROTEINMETABOLISM PHOSPHOPROTEIN PROTEASE SECRETED SERINE PROTSTEROID METABOLISM ZYMOGEN HYDROLASE-IMMUNE SYSTEM COMPLE
Ref.: HEPARAN SULFATE PROTEOGLYCANS PRESENT PCSK9 TO THE RECEPTOR. NAT COMMUN V. 8 503 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 15 families.
1 5OCA Kd = 180 uM TWD TWA n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 5OCA Kd = 180 uM TWD TWA n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5OCA Kd = 180 uM TWD TWA n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: TWD TWA; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: TWD TWA; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
Feedback