Receptor
PDB id Resolution Class Description Source Keywords
5NTH 2.5 Å EC: 3.4.11.- STRUCTURE OF LEUCYL AMINOPEPTIDASE FROM LEISHMANIA MAJOR IN WITH ACTINONIN LEISHMANIA MAJOR M17 LEUCYL AMINOPEPTIDASE AMINOPEPTIDASE LEISHMANIA MAJOR ACTINONIN HYDROLASE
Ref.: STRUCTURAL CHARACTERIZATION OF ACIDIC M17 LEUCINE AMINOPEPTIDASES FROM THE TRITRYPS AND EVALUATION OF ROLE IN NUTRIENT STARVATION INTRYPANOSOMA BRUCEI. MSPHERE V. 2 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MN A:602;
A:603;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
54.938 Mn [Mn+2...
BCT A:601;
 Invalid;
 none;
 submit data
61.017 C H O3 C(=O)...
BB2 A:604;
 Valid;
 none;
 submit data
385.498 C19 H35 N3 O5 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5NTH 2.5 Å EC: 3.4.11.- STRUCTURE OF LEUCYL AMINOPEPTIDASE FROM LEISHMANIA MAJOR IN WITH ACTINONIN LEISHMANIA MAJOR M17 LEUCYL AMINOPEPTIDASE AMINOPEPTIDASE LEISHMANIA MAJOR ACTINONIN HYDROLASE
Ref.: STRUCTURAL CHARACTERIZATION OF ACIDIC M17 LEUCINE AMINOPEPTIDASES FROM THE TRITRYPS AND EVALUATION OF ROLE IN NUTRIENT STARVATION INTRYPANOSOMA BRUCEI. MSPHERE V. 2 2018
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5NTH - BB2 C19 H35 N3 O5 CCCCC[C@H]....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5NTH - BB2 C19 H35 N3 O5 CCCCC[C@H]....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 223 families.
1 5NTH - BB2 C19 H35 N3 O5 CCCCC[C@H]....
2 5NTD - BES C16 H24 N2 O4 CC(C)C[C@@....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: BB2; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 BB2 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: BB2; Similar ligands found: 1
No: Ligand Similarity coefficient
1 BB1 0.8743
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5NTH; Ligand: BB2; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5nth.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5NTH; Ligand: BB2; Similar sites found with APoc: 22
This union binding pocket(no: 2) in the query (biounit: 5nth.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 4ZY1 4U5 31.4176
2 4ZY1 4U5 31.4176
3 4ZY1 4U5 31.4176
4 4ZY1 4U5 31.4176
5 4ZY1 4U5 31.4176
6 4ZY1 4U5 31.4176
7 4ZY1 4U5 31.4176
8 4ZY1 4U5 31.4176
9 4ZY1 4U5 31.4176
10 4ZY1 4U5 31.4176
11 3H8G BES 31.5985
12 3H8G BES 31.5985
13 3H8G BES 31.5985
14 3H8G BES 31.5985
15 3H8G BES 31.5985
16 3H8G BES 31.5985
17 4ZLA BES 37.0518
18 4ZLA BES 37.0518
19 4ZLA BES 37.0518
20 4ZLA BES 37.0518
21 4ZLA BES 37.0518
22 4ZLA BES 37.0518
Pocket No.: 3; Query (leader) PDB : 5NTH; Ligand: BB2; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5nth.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5NTH; Ligand: BB2; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5nth.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 5NTH; Ligand: BB2; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 5nth.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 5NTH; Ligand: BB2; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 5nth.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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