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Receptor
PDB id Resolution Class Description Source Keywords
5NLD 0.96 Å NON-ENZYME: BINDING CHICKEN GRIFIN (CRYSTALLISATION PH: 7.5) GALLUS GALLUS GALECTIN RELATED PROTEIN SUGAR BINDING PROTEIN
Ref.: CHICKEN GRIFIN: STRUCTURAL CHARACTERIZATION IN CRYS IN SOLUTION. BIOCHIMIE V. 146 127 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LBT B:201;
Valid;
none;
submit data
342.296 C12 H22 O11 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5NLD 0.96 Å NON-ENZYME: BINDING CHICKEN GRIFIN (CRYSTALLISATION PH: 7.5) GALLUS GALLUS GALECTIN RELATED PROTEIN SUGAR BINDING PROTEIN
Ref.: CHICKEN GRIFIN: STRUCTURAL CHARACTERIZATION IN CRYS IN SOLUTION. BIOCHIMIE V. 146 127 2018
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 5NM1 - LBT C12 H22 O11 C([C@@H]1[....
2 5NLD - LBT C12 H22 O11 C([C@@H]1[....
3 5NMJ - LBT C12 H22 O11 C([C@@H]1[....
4 5NLH - LBT C12 H22 O11 C([C@@H]1[....
5 5NLE - LBT C12 H22 O11 C([C@@H]1[....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 5NM1 - LBT C12 H22 O11 C([C@@H]1[....
2 5NLD - LBT C12 H22 O11 C([C@@H]1[....
3 5NMJ - LBT C12 H22 O11 C([C@@H]1[....
4 5NLH - LBT C12 H22 O11 C([C@@H]1[....
5 5NLE - LBT C12 H22 O11 C([C@@H]1[....
50% Homology Family (109)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 5NF9 Kd = 4.7 uM 8VW C22 H32 N2 O12 CC(=O)N[C@....
2 5E8A Kd = 0.034 uM 5KS C28 H30 F2 N6 O8 S c1cc(ccc1c....
3 1A3K - GAL NAG n/a n/a
4 3T1M Kd = 0.91 mM DQT C23 H27 N O7 Cc1ccc(cc1....
5 4LBL Kd = 11 uM BGC SIA GAL n/a n/a
6 2NMN Kd = 260 uM GAL BGC n/a n/a
7 4R9B - LAT C12 H22 O11 C([C@@H]1[....
8 2NN8 Kd = 260 uM LAT C12 H22 O11 C([C@@H]1[....
9 4JC1 Kd = 50 uM TDG C12 H22 O10 S C([C@@H]1[....
10 4R9A - LAT C12 H22 O11 C([C@@H]1[....
11 5EXO - 5SY C19 H22 O9 CC(=O)O[C@....
12 5ODY Kd = 7.5 nM 9SK C30 H28 F5 N3 O11 S c1cc(c(c2c....
13 5E88 Kd = 0.065 uM 5KT C24 H28 N6 O8 S3 c1cscc1c2c....
14 4R9D - LAT C12 H22 O11 C([C@@H]1[....
15 1KJL Kd = 67 uM GAL NAG n/a n/a
16 3T1L Kd = 0.55 mM MQT C17 H22 O8 Cc1ccc(cc1....
17 2XG3 Kd = 18.2 uM UNU GAL NAG n/a n/a
18 4LBJ Kd = 0.39 uM GAL NAG GAL BGC n/a n/a
19 4R9C - LAT C12 H22 O11 C([C@@H]1[....
20 3ZSJ Kd = 231 uM LAT C12 H22 O11 C([C@@H]1[....
21 4LBM Kd = 0.97 uM BGC GAL NAG GAL n/a n/a
22 1KJR Kd = 0.88 uM BEK GAL NAG n/a n/a
23 6EOL Kd = 0.037 uM BKH C20 H16 Cl2 F3 N3 O4 S c1cc(c(cc1....
24 6G0V Kd = 166 uM EGZ C18 H25 N O13 S C1[C@H](NC....
25 3AYE - LAT C12 H22 O11 C([C@@H]1[....
26 6EOG Kd = 1.6 uM BKK C20 H17 Cl F3 N3 O4 S c1cc(cc(c1....
27 5E89 Kd = 0.014 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
28 4LBO Kd = 1.7 uM BGC GAL SIA n/a n/a
29 2NMO Kd = 260 uM GAL BGC n/a n/a
30 3AYC Kd = 57 uM GAL NGA GAL BGC SIA n/a n/a
31 4JCK Kd = 4.3 mM 1LL C12 H22 O10 S C([C@@H]1[....
32 5NFA Kd = 5.6 uM 8VQ C24 H36 N2 O12 CC(=O)N[C@....
33 4LBK Kd = 0.32 uM GAL NAG GAL BGC n/a n/a
34 5OAX Kd = 12 nM 9Q5 C30 H30 F3 N3 O11 S c1cc(cc(c1....
35 4RL7 - LAT C12 H22 O11 C([C@@H]1[....
36 3AYD Kd = 65 uM NPO A2G GAL n/a n/a
37 4LBN Kd = 0.65 uM GLC GAL NAG GAL n/a n/a
38 1G86 - NEQ C6 H7 N O2 CCN1C(=O)C....
39 1QKQ - MAN C6 H12 O6 C([C@@H]1[....
40 1HDK - PMB C6 H5 Hg O3 S c1cc(ccc1S....
41 2D6N - GAL NAG n/a n/a
42 2D6M - LBT C12 H22 O11 C([C@@H]1[....
43 2D6O - NAG GAL GAL NAG n/a n/a
44 4XBN Kd = 93 uM GAL NAG n/a n/a
45 5H9R Kd = 0.84 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
46 5H9P Kd = 0.068 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
47 5DG2 - GAL GLC n/a n/a
48 5EWS - GAL BGC n/a n/a
49 5NM1 - LBT C12 H22 O11 C([C@@H]1[....
50 5NLD - LBT C12 H22 O11 C([C@@H]1[....
51 5NMJ - LBT C12 H22 O11 C([C@@H]1[....
52 5NLH - LBT C12 H22 O11 C([C@@H]1[....
53 5NLE - LBT C12 H22 O11 C([C@@H]1[....
54 4XBL Kd = 340 uM GAL NAG n/a n/a
55 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
56 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
57 3OY8 Kd = 220 uM GAL GCO n/a n/a
58 2EAL - GAL NGA A2G n/a n/a
59 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
60 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
61 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
62 2ZHM - NAG GAL GAL NAG GAL n/a n/a
63 2EAK - LBT C12 H22 O11 C([C@@H]1[....
64 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
65 5H9S Kd = 87 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
66 5H9Q Kd = 38 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
67 4XBQ Kd = 270 uM GAL NAG n/a n/a
68 6A62 - LAT C12 H22 O11 C([C@@H]1[....
69 6A64 - LAT C12 H22 O11 C([C@@H]1[....
70 6A63 - LAT C12 H22 O11 C([C@@H]1[....
71 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
72 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
73 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
74 3VKO - SIA GAL NAG n/a n/a
75 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
76 5T7T Kd = 2.1 uM GAL NAG n/a n/a
77 3I8T Kd = 600 uM LBT C12 H22 O11 C([C@@H]1[....
78 3WV6 - GAL BGC n/a n/a
79 3NV2 - GAL NDG n/a n/a
80 3NV4 - SIA GAL BGC n/a n/a
81 3NV3 - GAL NAG MAN n/a n/a
82 3WUD Kd = 41 uM GLC GAL n/a n/a
83 3GAL - 1GN C6 H13 N O5 C([C@@H]1[....
84 4UW6 - VV7 C69 H73 N20 O39 [H]1c2c(cc....
85 2GAL - GAL C6 H12 O6 C([C@@H]1[....
86 4GAL - GAL BGC n/a n/a
87 4UW3 - 50G C31 H50 N10 O18 c1c(nnn1[C....
88 4UW4 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
89 3ZXE Kd = 450 uM PGZ C22 H28 N O8 P S Cc1ccc(cc1....
90 5GAL - NAG GAL n/a n/a
91 4UW5 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
92 1A78 - TDG C12 H22 O10 S C([C@@H]1[....
93 5DUW Kd = 510 uM 5GO C12 H22 O14 S C([C@@H]1[....
94 5DUV Kd = 1300 uM LAT C12 H22 O11 C([C@@H]1[....
95 5DUX Kd = 380 uM LAT FUC n/a n/a
96 4WVV - LBT C12 H22 O11 C([C@@H]1[....
97 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
98 4YLZ Kd = 270 uM LAT NAG GAL n/a n/a
99 5CBL - LAT C12 H22 O11 C([C@@H]1[....
100 4YM0 Kd = 510 uM LAT NAG GAL n/a n/a
101 4YM2 Kd = 1400 uM SGA BGC n/a n/a
102 4YM3 Kd = 1900 uM LAT C12 H22 O11 C([C@@H]1[....
103 4YM1 Kd = 580 uM LAT FUC n/a n/a
104 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
105 1WLD - GAL BGC n/a n/a
106 6FOF - LAT C12 H22 O11 C([C@@H]1[....
107 5NFB Kd = 0.77 uM 8VT C30 H40 N2 O13 CC(=O)N[C@....
108 5NF7 Kd = 37.5 uM 8VZ C16 H28 N2 O11 CC(=O)N[C@....
109 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LBT; Similar ligands found: 333
No: Ligand ECFP6 Tc MDL keys Tc
1 GLA GLA 1 1
2 GAL BGC 1 1
3 GLC GAL 1 1
4 BMA GAL 1 1
5 LBT 1 1
6 BGC GAL 1 1
7 CBI 1 1
8 MAL 1 1
9 CBK 1 1
10 BGC BMA 1 1
11 N9S 1 1
12 MAB 1 1
13 LAT 1 1
14 GLA GAL 1 1
15 B2G 1 1
16 BMA BMA BMA 0.909091 1
17 GLA GAL GLC 0.909091 1
18 GLC BGC BGC 0.909091 1
19 GLC BGC BGC BGC 0.909091 1
20 GLC GLC GLC GLC GLC 0.909091 1
21 CT3 0.909091 1
22 BGC GLC GLC GLC 0.909091 1
23 BGC BGC BGC BGC 0.909091 1
24 CTT 0.909091 1
25 CTR 0.909091 1
26 GLC GAL GAL 0.909091 1
27 MAN BMA BMA BMA BMA BMA 0.909091 1
28 BGC BGC BGC GLC 0.909091 1
29 CEY 0.909091 1
30 B4G 0.909091 1
31 BGC BGC BGC 0.909091 1
32 GLC GLC BGC 0.909091 1
33 CE5 0.909091 1
34 BGC BGC BGC BGC BGC BGC 0.909091 1
35 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.909091 1
36 BMA BMA BMA BMA BMA BMA 0.909091 1
37 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
38 GLA GAL BGC 0.909091 1
39 MLR 0.909091 1
40 MAN BMA BMA 0.909091 1
41 BGC GLC GLC GLC GLC GLC GLC 0.909091 1
42 BMA BMA BMA BMA BMA 0.909091 1
43 BGC BGC GLC 0.909091 1
44 MAN MAN BMA BMA BMA BMA 0.909091 1
45 BGC GLC GLC 0.909091 1
46 BGC BGC BGC BGC BGC 0.909091 1
47 MT7 0.909091 1
48 GLC BGC BGC BGC BGC 0.909091 1
49 CE6 0.909091 1
50 MTT 0.909091 1
51 CE8 0.909091 1
52 MAN BMA BMA BMA BMA 0.909091 1
53 GLC BGC GLC 0.909091 1
54 DXI 0.909091 1
55 GLC BGC BGC BGC BGC BGC 0.909091 1
56 CEX 0.909091 1
57 GAL GAL GAL 0.909091 1
58 BMA MAN BMA 0.909091 1
59 BGC GLC GLC GLC GLC 0.909091 1
60 GLA GAL GAL 0.816327 1
61 BGC BGC BGC BGC BGC BGC BGC BGC 0.754717 1
62 BMA BMA GLA BMA BMA 0.689655 1
63 XYT 0.685185 0.767442
64 LAT GLA 0.680851 1
65 GLC GLC GLC BGC 0.672414 1
66 U63 0.647059 0.891892
67 MMA MAN 0.64 0.942857
68 DR5 0.64 0.942857
69 GLA EGA 0.634615 0.942857
70 GAL FUC 0.615385 0.941176
71 2M4 0.612245 1
72 BGC GAL FUC 0.610169 0.970588
73 FUC GAL GLC 0.610169 0.970588
74 8B7 0.610169 0.970588
75 GLC GAL FUC 0.610169 0.970588
76 LAT FUC 0.610169 0.970588
77 BGC GLA GAL FUC 0.609375 0.970588
78 BQZ 0.608696 0.909091
79 BGC GAL NAG GAL 0.606061 0.733333
80 GAL NAG GAL GLC 0.606061 0.733333
81 BMA BMA BMA BMA 0.603448 0.941176
82 M3M 0.6 1
83 LB2 0.6 1
84 NGR 0.6 1
85 MAN GLC 0.6 1
86 MAL EDO 0.592593 0.942857
87 BGC BGC BGC XYS GAL 0.588235 0.942857
88 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.588235 0.942857
89 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.588235 0.942857
90 BGC BGC BGC XYS BGC BGC 0.588235 0.942857
91 LAT NAG GAL 0.588235 0.733333
92 GLC GAL NAG GAL 0.588235 0.733333
93 NGA GAL BGC 0.587302 0.733333
94 TRE 0.581395 1
95 ABD 0.57971 0.75
96 NLC 0.578947 0.733333
97 NDG GAL 0.578947 0.733333
98 GAL NDG 0.578947 0.733333
99 5GO 0.578947 0.66
100 DEL 0.574074 0.970588
101 MVP 0.571429 0.733333
102 GAL NGA GLA BGC GAL 0.571429 0.733333
103 GAL BGC BGC XYS 0.569231 0.942857
104 SGA BGC 0.568965 0.66
105 BGC BGC 0.566038 0.914286
106 BMA BMA 0.566038 0.914286
107 GLC GLC XYP 0.557377 1
108 BGC BGC XYS BGC 0.552239 0.942857
109 NAG GAL BGC 0.552239 0.733333
110 GLA GAL BGC 5VQ 0.551724 0.891892
111 G2F BGC BGC BGC BGC BGC 0.55 0.868421
112 GLA MBG 0.54902 0.942857
113 GLC ACI G6D BGC 0.547945 0.733333
114 GLC G6D ACI GLC 0.547945 0.733333
115 GLC ACI GLD GLC 0.547945 0.733333
116 GLC G6D ADH GLC 0.547945 0.733333
117 GLC BGC BGC BGC BGC BGC BGC 0.545455 1
118 BGC BGC BGC GLC BGC BGC 0.545455 1
119 BMA BMA MAN 0.535714 1
120 MAN MAN BMA 0.535714 1
121 NGA GLA GAL BGC 0.535211 0.733333
122 GAL BGC BGC BGC XYS BGC XYS 0.533333 0.942857
123 BGC BGC BGC XYS BGC XYS GAL 0.533333 0.942857
124 BGC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
125 BGC BGC XYS BGC XYS BGC XYS 0.528571 0.942857
126 GLC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
127 BMA MAN MAN MAN 0.525424 1
128 GLA GAL GLC NBU 0.52459 0.846154
129 FUC BGC GAL 0.52459 0.970588
130 GLC GLC G6D ACI GLC GLC GLC 0.519481 0.733333
131 GLC ACI GLD GAL 0.519481 0.702128
132 GLC ACI G6D GLC 0.519481 0.702128
133 BGC BGC BGC FRU 0.516129 0.868421
134 DOM 0.509091 0.942857
135 G3I 0.507937 0.767442
136 LMU 0.507937 0.785714
137 DMU 0.507937 0.785714
138 UMQ 0.507937 0.785714
139 OXZ BGC BGC 0.507937 0.6875
140 G2I 0.507937 0.767442
141 LMT 0.507937 0.785714
142 GAL XYS XYS BGC BGC BGC XYS GAL BGC 0.506329 0.942857
143 BGC BGC XYS BGC GAL XYS BGC XYS GAL 0.506329 0.942857
144 GAL BGC BGC BGC XYS XYS 0.506329 0.942857
145 GLC BGC BGC XYS BGC XYS XYS GAL GAL 0.506329 0.942857
146 GLC BGC BGC XYS BGC XYS XYS GAL 0.506329 0.942857
147 FMO 0.5 0.868421
148 MAN BMA NAG 0.5 0.733333
149 SOR GLC GLC 0.5 0.970588
150 GLA GAL NAG 0.5 0.733333
151 8VZ 0.5 0.673469
152 ACR GLC GLC GLC 0.493827 0.702128
153 GLC GLC DAF BGC 0.493827 0.702128
154 GLC GLC ACI G6D GLC GLC 0.493827 0.702128
155 ARE 0.493827 0.733333
156 GLC GLC AGL HMC GLC 0.493827 0.702128
157 AAO 0.493827 0.733333
158 GLC GLC XYS 0.492308 0.970588
159 MAN BMA MAN 0.491803 1
160 CGC 0.491525 0.941176
161 5QP 0.491228 0.885714
162 GAL MBG 0.490909 0.942857
163 MDM 0.490909 0.942857
164 RZM 0.490909 0.688889
165 M13 0.490909 0.942857
166 GAL NAG MAN 0.485294 0.733333
167 SOR GLC GLC GLC 0.484848 0.970588
168 GLO GLC GLC GLC 0.484848 0.970588
169 6UZ 0.484848 0.846154
170 LAG 0.484848 0.6
171 GAL BGC NAG GAL 0.478873 0.733333
172 GTM BGC BGC 0.477612 0.868421
173 10M 0.477612 0.733333
174 MAN MAN MAN MAN 0.476923 1
175 MAN MAN BMA MAN 0.476923 1
176 GLA GAL NAG FUC GAL GLC 0.47619 0.717391
177 GAL GAL SO4 0.47619 0.66
178 NAG BMA 0.47619 0.653061
179 GAL NGA 0.47541 0.733333
180 A2G GAL 0.47541 0.733333
181 GAL A2G 0.47541 0.733333
182 GLA BMA 0.472727 1
183 GLC BGC 0.472727 1
184 GAL GAL 0.472727 1
185 GLA GLC 0.472727 1
186 BGC GLA 0.472727 1
187 GAL GLC 0.472727 1
188 GLA BGC 0.472727 1
189 BMA GLA 0.472727 1
190 BMA MAN 0.472727 1
191 MAN MAN 0.472727 1
192 BGC GLC 0.472727 1
193 MLB 0.472727 1
194 GLC GLC 0.472727 1
195 MAN BMA 0.472727 1
196 LAK 0.472727 1
197 NPJ 0.470588 0.622642
198 FUC GAL NAG GAL BGC 0.469136 0.717391
199 GAL GLC NAG GAL FUC 0.469136 0.717391
200 GLC NAG GAL GAL FUC 0.469136 0.717391
201 MAN MAN MAN GLC 0.46875 1
202 ABL 0.466667 0.702128
203 FRU GAL 0.465517 0.842105
204 BMA FRU 0.465517 0.842105
205 DAF BGC 0.464789 0.733333
206 DAF GLC 0.464789 0.733333
207 TM6 0.463768 0.916667
208 BGC SGC BGC SGC BGC SGC BGC SGC 0.463768 0.916667
209 LSE 0.462687 0.6875
210 FUC GLA GLA 0.460317 0.970588
211 GAL GAL FUC 0.460317 0.970588
212 FUC GAL GLA 0.460317 0.970588
213 GLA GLA FUC 0.460317 0.970588
214 GLA GAL FUC 0.460317 0.970588
215 IFM BMA 0.457627 0.711111
216 9MR 0.457627 0.744186
217 IFM BGC 0.457627 0.711111
218 BMA IFM 0.457627 0.711111
219 BGC OXZ 0.457627 0.666667
220 RCB 0.457143 0.622642
221 GLO GLC GLC 0.457143 0.942857
222 MAN MAN MAN 0.45614 1
223 GLC GLC GLC GLC BGC 0.45614 1
224 GLC GLC GLC GLC GLC BGC 0.45614 1
225 BMA MAN MAN 0.45614 1
226 GLC GLC GLC 0.45614 1
227 WOO 0.454545 0.848485
228 GIV 0.454545 0.848485
229 BGC 0.454545 0.848485
230 ALL 0.454545 0.848485
231 GAL 0.454545 0.848485
232 GLA 0.454545 0.848485
233 GLC 0.454545 0.848485
234 GXL 0.454545 0.848485
235 BMA 0.454545 0.848485
236 MAN 0.454545 0.848485
237 ACI GLD GLC GAL 0.453333 0.733333
238 DAF BGC GLC 0.453333 0.733333
239 DAF GLC GLC 0.453333 0.733333
240 MGL SGC BGC BGC 0.450704 0.868421
241 MGL SGC GLC GLC 0.450704 0.868421
242 CM5 0.450704 0.891892
243 MAN MAN MAN BMA MAN 0.450704 1
244 BGC BGC SGC MGL 0.450704 0.868421
245 MAN MNM 0.45 0.702128
246 GLC DMJ 0.45 0.695652
247 A2G GAL BGC FUC 0.45 0.717391
248 NOJ GLC 0.45 0.695652
249 NOY BGC 0.45 0.702128
250 BMA MAN MAN MAN MAN 0.449275 1
251 GCS GCS 0.448276 0.767442
252 PA1 GCS 0.448276 0.767442
253 M5S 0.447761 1
254 MAN BMA MAN MAN MAN 0.447761 1
255 TXT 0.447368 0.767442
256 GAC 0.447368 0.767442
257 GLC GAL NAG GAL FUC FUC 0.447059 0.702128
258 BGC GAL NAG GAL FUC FUC 0.447059 0.702128
259 GAL NAG GAL NAG GAL NAG 0.445946 0.673469
260 NAG GAL GAL NAG GAL 0.445946 0.6875
261 NAG GAL GAL NAG 0.445946 0.6875
262 MA4 0.444444 0.891892
263 QV4 0.444444 0.733333
264 MAN DGO 0.440678 0.914286
265 3SA 0.44 0.733333
266 Z6J 0.439024 0.742857
267 GLC GLC GLC PO4 SGC GLC 0.439024 0.66
268 AHR 0.439024 0.742857
269 RIB 0.439024 0.742857
270 FUB 0.439024 0.742857
271 32O 0.439024 0.742857
272 T6P 0.438596 0.767442
273 MMA 0.4375 0.857143
274 MBG 0.4375 0.857143
275 GYP 0.4375 0.857143
276 AMG 0.4375 0.857143
277 MAN G63 0.435484 0.653061
278 GDQ GLC 0.435484 0.666667
279 4MU BGC BGC 0.434211 0.767442
280 ISX 0.433333 0.761905
281 MAN 7D1 0.431034 0.888889
282 ACR 0.43038 0.733333
283 QPS 0.43038 0.733333
284 GAL MGC 0.428571 0.702128
285 4MU BGC BGC BGC BGC 0.428571 0.767442
286 GAL NDG FUC 0.422535 0.717391
287 FUC NDG GAL 0.422535 0.717391
288 HMC AGL GLC 0.421053 0.717391
289 KHO 0.421053 0.888889
290 GCS GCS GCS 0.419355 0.767442
291 GCS GCS GCS GCS GCS 0.419355 0.767442
292 GCS GCS GCS GCS GCS GCS 0.419355 0.767442
293 GAL NAG GAL 0.418919 0.702128
294 NGT GAL 0.41791 0.66
295 GAL NGT 0.41791 0.66
296 P3M 0.41791 0.767442
297 GLC GAL NAG GAL FUC A2G 0.417582 0.673469
298 A2G GAL NAG FUC GAL GLC 0.417582 0.673469
299 TUR 0.416667 0.842105
300 BTU 0.416667 0.842105
301 GLC FRU 0.416667 0.842105
302 GLA MAN ABE 0.414286 0.916667
303 NAG NAG BMA 0.413333 0.634615
304 NAG NDG BMA 0.413333 0.634615
305 ACR GLC GLC GLC GLC 0.4125 0.702128
306 ACR GLC 0.4125 0.702128
307 AHR AHR AHR AHR AHR AHR 0.410714 0.857143
308 FUB AHR AHR 0.410714 0.857143
309 VAM 0.409836 0.868421
310 GLF B8D 0.409836 0.775
311 DAF GLC DAF GLC GLC 0.409639 0.702128
312 ACI GLD GLC ACI G6D BGC 0.409639 0.702128
313 AC1 GLC AC1 BGC 0.409639 0.702128
314 ACI G6D GLC ACI G6D BGC 0.409639 0.702128
315 BGC GLC AC1 GLC GLC GLC AC1 0.409639 0.702128
316 ACI GLD GLC GLC GLC ACI GLD GLC GAL 0.409639 0.702128
317 MAN MMA MAN 0.409091 0.942857
318 FUB AHR 0.407407 0.857143
319 AHR AHR 0.407407 0.857143
320 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.406977 0.653061
321 4U0 0.406593 0.66
322 BGC BGC SSG PIH 0.405063 0.767442
323 GLA MAN RAM ABE 0.405063 0.891892
324 G1P 0.403846 0.697674
325 GL1 0.403846 0.697674
326 XGP 0.403846 0.697674
327 M1P 0.403846 0.697674
328 GLC IFM 0.403226 0.727273
329 MAN IFM 0.403226 0.727273
330 MAN MAN MAN MAN MAN MAN MAN 0.402597 1
331 XZZ BGC BGC 0.402439 0.702128
332 ACG 0.402299 0.695652
333 FUC GAL 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5NLD; Ligand: LBT; Similar sites found with APoc: 397
This union binding pocket(no: 1) in the query (biounit: 5nld.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5FU3 BGC BGC BGC None
2 5N2F 8HW None
3 4RFR RHN None
4 1N5S ADL None
5 1YRX FMN None
6 5IXG OTP None
7 2Z77 HE7 None
8 5N2D 8J8 None
9 4XV1 904 None
10 2CM4 RCL None
11 2YJ0 420 None
12 5HA0 LTD None
13 3QRC SCR None
14 5IXH OTP None
15 1X0P FAD None
16 4CQE CQE None
17 2BYC FMN None
18 5ML3 DL3 None
19 1ZNY GDP None
20 3T50 FMN None
21 4IKR PVP None
22 1EYE PMM None
23 4MNS 2AX None
24 6GBV FMN None
25 5FPX GLY SER SER HIS HIS HIS HIS HIS None
26 1M5W DXP None
27 5J75 6GQ None
28 5HV0 AKG None
29 1YVD GNP None
30 1VJY 460 None
31 5NIU 8YZ None
32 6GNO XDI None
33 4MA6 28E None
34 3SLS 77D None
35 5HCY 60D None
36 2RIF AMP None
37 4GJ3 0XP None
38 4WN5 MVC None
39 5I7S E9P None
40 5I7S NAD None
41 2XK9 XK9 None
42 2PR5 FMN None
43 4P6C RES None
44 4WUJ FMN None
45 4R38 RBF None
46 1OIV GDP None
47 6D6L FY4 None
48 2Z6C FMN None
49 5DEY 59T 1.43885
50 1VRP ADP 1.43885
51 5MZI FAD 1.43885
52 5MZI FYK 1.43885
53 5XVG 8FX 1.43885
54 1YKD CMP 2.15827
55 5EOB 5QQ 2.15827
56 5A65 TPP 2.15827
57 4G31 0WH 2.15827
58 5ZM4 AKG 2.15827
59 4WW8 VD9 2.15827
60 3OBK PBG 2.15827
61 4YKG FAD 2.15827
62 4YKG NAD 2.15827
63 3AMN CBI 2.15827
64 3AMN CBK 2.15827
65 3TYZ XHP 2.15827
66 5ZM4 9FU 2.15827
67 3TYZ PAB 2.15827
68 4NPL AKG 2.15827
69 6D61 4AA 2.15827
70 6EXF LYS 2.15827
71 2A1L PCW 2.8777
72 3GC8 B45 2.8777
73 3MPB FRU 2.8777
74 3LVW GSH 2.8777
75 2DKH 3HB 2.8777
76 2OO8 RAJ 2.8777
77 4XO8 KGM 2.8777
78 5I0U DCY 2.8777
79 1Y2F WAI 2.8777
80 2Y3S TIR 2.8777
81 5AYT L6Y 2.8777
82 4GQP B40 2.8777
83 4RGA 3PV 2.8777
84 5SVV FMN 2.91971
85 5EZU MYR 3.37079
86 4DXD 9PC 3.53535
87 5DRB 5FJ 3.59712
88 2YG2 FLC 3.59712
89 2YG2 S1P 3.59712
90 4D5B ACX 3.59712
91 3E8N VRA 3.59712
92 3E8N ATP 3.59712
93 5YIC 8VO 3.59712
94 3QP8 HL0 3.59712
95 1M15 ADP 3.59712
96 1M15 ARG 3.59712
97 3QP6 HL6 3.59712
98 2YNE YNE 3.59712
99 2YNE NHW 3.59712
100 3PP0 03Q 3.59712
101 2YKL NLD 3.59712
102 3B6R ADP 3.59712
103 6GIN IR2 3.59712
104 2VEG PMM 3.59712
105 5BU3 4W9 3.59712
106 4RYV ZEA 3.59712
107 4GCZ FMN 3.59712
108 3GNE FLC 3.59712
109 3UN3 G16 3.59712
110 5X7Q GLC GLC GLC GLC GLC 3.59712
111 4XSH GSP 3.59712
112 3NX2 FER 3.59712
113 4BVA T3 3.59712
114 2JEN GLC GLC BGC XYS BGC XYS 3.59712
115 2WA4 069 4.31655
116 4CSV STI 4.31655
117 1MH5 HAL 4.31655
118 4W8B GLC BGC BGC XYS BGC XYS XYS GAL 4.31655
119 3KFF ZBT 4.31655
120 3KFF XBT 4.31655
121 3N0Y APC 4.31655
122 5VCV 1N1 4.31655
123 5HES 032 4.31655
124 4BR5 ANP 4.31655
125 6MPT C30 4.31655
126 1ST0 GTG 4.31655
127 1QIN GIP 4.31655
128 3MJH GTP 4.31655
129 1CLU DBG 4.31655
130 4P8K FAD 4.31655
131 4P8K 38C 4.31655
132 2I4O ATP 4.31655
133 3PTQ NFG 4.31655
134 5YU3 PRO 4.31655
135 1TU3 GNP 4.31655
136 1NSZ GLC 4.31655
137 3QP4 HL0 4.31655
138 4ZL4 4PK 4.31655
139 1R2Q GNP 4.31655
140 1EWF PC1 4.31655
141 6GL0 GLC BGC BGC 4.31655
142 4QM9 CYS 4.31655
143 5YU3 NAD 4.31655
144 1TOI HCI 4.31655
145 4ZSI 4R1 5.03597
146 1U0A BGC BGC BGC BGC 5.03597
147 4LOO SB4 5.03597
148 1GT4 UNA 5.03597
149 1UNB PN1 5.03597
150 1UNB AKG 5.03597
151 4ZSI GLP 5.03597
152 4QRH 0O2 5.03597
153 1TT8 PHB 5.03597
154 2E56 MYR 5.03597
155 4YGF AZM 5.03597
156 2VFT SOR 5.03597
157 2XVD AS6 5.03597
158 4J7Q B7N 5.03597
159 5FBN 5WF 5.03597
160 3MTX PGT 5.03597
161 3STD MQ0 5.03597
162 4WVO 3UZ 5.03597
163 2J7T 274 5.03597
164 1UU6 BGC BGC BGC BGC 5.03597
165 5JSP DQY 5.03597
166 3DLG GWE 5.03597
167 4QTB 38Z 5.03597
168 2R5V HHH 5.03597
169 2IO8 ADP 5.03597
170 3NC9 TR3 5.03597
171 3GFZ FMN 5.03597
172 4LX0 BEF GDP 5.03597
173 2J3M PRI 5.03597
174 2J3M ATP 5.03597
175 2BYS LOB 5.03597
176 1LFO OLA 5.46875
177 1KGI T4A 5.51181
178 4XIZ LPP 5.71429
179 3L8W XAN 5.7554
180 4NFN 2KC 5.7554
181 2I74 MAN MAN MAN MAN 5.7554
182 6FE1 V14 5.7554
183 5Y72 DST 5.7554
184 1Z03 OCH 5.7554
185 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 5.7554
186 5U98 1KX 5.7554
187 4RF7 ARG 5.7554
188 4BG4 ADP 5.7554
189 2OBD 2OB 5.7554
190 1NYW DAU 5.7554
191 3WW2 LPK 5.7554
192 1LEK GLU GLN TYR LYS PHE TYR SER VAL 5.7554
193 3JRS A8S 5.7554
194 4HWT 1B2 5.7554
195 1PN0 IPH 5.7554
196 3E2M E2M 5.7554
197 1VA6 P2S 5.7554
198 1VA6 ADP 5.7554
199 3B00 16A 5.7554
200 4FFG 0U8 5.7554
201 1F52 ADP 5.7554
202 5EYK 5U5 5.7554
203 5N0L ILE 5.7554
204 3W8X FTK 5.7554
205 3PQB VGP 5.7554
206 4NW6 2NS 5.7554
207 6CLV 6MB 5.7554
208 1SNN 5RP 5.7554
209 3TNF GNP 5.7554
210 1N20 3AG 5.7554
211 1DMY AZM 5.7554
212 4C2V YJA 5.7554
213 5K21 6QF 5.7554
214 5B09 4MX 5.76923
215 5TBM 79A 6.08696
216 4IE6 UN9 6.47482
217 5VNF VAL THR SER VAL VAL 6.47482
218 4HWS 1B3 6.47482
219 4L4V 1VY 6.47482
220 5H5A 6OU 6.47482
221 3AXX CBI 6.47482
222 3E85 BSU 6.47482
223 5YBN AKG 6.47482
224 1EX7 5GP 6.47482
225 4TSZ ACE GLN ALC ASP LEU ZCL 6.47482
226 6C1S EFV 6.47482
227 5AB1 BCD TA5 HP6 MAN 6.47482
228 4EWH T77 6.47482
229 3SHR CMP 6.47482
230 4XOE KGM 6.47482
231 1S4M LUM 6.47482
232 4V24 GYR 6.47482
233 5W0N UPU 6.47482
234 4S3F 43W 6.47482
235 5VC5 96M 6.47482
236 5DJU FMN 6.55738
237 5LJB RTL 6.66667
238 3VMG 9CA 6.95652
239 1DZK PRZ 7.19424
240 5H2U 1N1 7.19424
241 1ZB6 DIN 7.19424
242 1ZB6 GST 7.19424
243 2AXR ABL 7.19424
244 4YZC STU 7.19424
245 4QDF 30Q 7.19424
246 3OZ2 OZ2 7.19424
247 4QDC ASD 7.19424
248 2HK5 1BM 7.19424
249 6G9I CXX 7.19424
250 3AGC RCC 7.19424
251 3NYC FAD 7.19424
252 3NYC IAR 7.19424
253 4G7A AZM 7.25806
254 3ZO7 K6H 7.44681
255 5KEW 6SB 7.63889
256 3FON VAL ASN ASP ILE PHE GLU ALA ILE 7.91367
257 3VQ2 LP4 LP5 MYR DAO 7.91367
258 6GR0 F8W 7.91367
259 4KBA 1QM 7.91367
260 1ERB ETR 7.91367
261 5EPQ OLA 7.91367
262 5WL1 D3D 7.91367
263 5WL1 CUY 7.91367
264 2JIG PD2 7.91367
265 5W4W 9WG 7.91367
266 4WUP 3UF 7.91367
267 4IAW LIZ 8.63309
268 4H2V AMP 8.63309
269 3MF2 AMP 8.63309
270 5W10 CMP 8.63309
271 2AGC DAO 8.63309
272 5O9W AKG 8.63309
273 5TUF TDC 8.63309
274 5TUF FAD 8.63309
275 3UH0 TSB 8.63309
276 2HZQ STR 8.63309
277 2XXP DSL 8.63309
278 3CBC DBS 8.63309
279 4PIV 2W4 8.63309
280 4POS NAG SIA GAL 8.63309
281 4JH6 FCN 8.69565
282 5DKK FMN 8.96552
283 5E2N V14 9.35252
284 4U0W 16G 9.35252
285 4QMN DB8 9.35252
286 4MP8 NAD 9.35252
287 4MP8 MLI 9.35252
288 2AG4 OLA 9.35252
289 1IIU RTL 9.35252
290 2AG4 LP3 9.35252
291 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 9.35252
292 1U6R ADP 9.35252
293 5DYO FLU 9.35252
294 1OLM VTQ 9.35252
295 5Y80 IRE 9.35252
296 3PG7 PTY 9.35252
297 2HV8 GTP 9.375
298 4H2W 5GP 9.70874
299 4H2X G5A 9.70874
300 4H2W AMP 9.70874
301 6E08 NAP 10.0719
302 3HY3 10F 10.0719
303 1GQG DCD 10.0719
304 3JU6 ANP 10.0719
305 5FI4 5XV 10.0719
306 1NX4 AKG 10.0719
307 5TVM PUT 10.0719
308 4OJ8 2TQ 10.0719
309 4YVN EBS 10.0719
310 5DXT 5H5 10.0719
311 6CC0 EWM 10.0719
312 4BPZ GLC BGC BGC 10.0719
313 3G3R ANP 10.0719
314 4K55 H6P 10.4839
315 5FXD H7Y 10.7914
316 4LA7 A1O 10.7914
317 4J36 1HR 10.7914
318 4Q0P 0MK 10.7914
319 1MJJ HAL 10.7914
320 6GW4 CHO 10.7914
321 2E0P CTT 10.7914
322 1UMZ BGC BGC XYS BGC XYS GAL 10.7914
323 4NG2 OHN 11.5044
324 3G08 FEE 11.5108
325 1ZM1 BGC BGC BGC 11.5108
326 6GVZ CHO 11.5108
327 3FW4 CAQ 11.5108
328 4QCK ASD 11.5108
329 5THY SAH 11.5108
330 3GL0 HXX 11.5108
331 5EFW FMN 11.6667
332 2P7Q GG6 12.0301
333 4NV7 COA 12.2302
334 3EEB IHP 12.2302
335 4D1J DGJ 12.2302
336 6EZ6 C5Z 12.2302
337 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 12.2302
338 2JDR L20 12.2302
339 2HFN FMN 12.9496
340 3B1Q NOS 12.9496
341 5EQY 5RA 12.9496
342 4U03 GTP 12.9496
343 4WOE ADP 13.6691
344 5XEG AKG 13.6691
345 3WDX BGC BGC GLC 13.6691
346 5GXU FAD 13.6691
347 3M3R BCD 13.6691
348 2VGD XYP XYP XYP FX3 13.6691
349 3FW9 SLX 13.6691
350 1NF3 GNP 14.0625
351 1BHX ASP PHE GLU GLU ILE 14.2857
352 1GP6 DH2 14.3885
353 1GP6 SIN 14.3885
354 1GP6 QUE 14.3885
355 5C3R AKG 14.3885
356 5C3R HMU 14.3885
357 4D06 NAR 14.3885
358 3PFG TLO 14.3885
359 3PFG SAM 14.3885
360 2GGH NLQ 14.3885
361 3E7O 35F 14.3885
362 1VYF OLA 14.8148
363 3AKK ADP 15.1079
364 4MZU TYD 15.1079
365 5NBW 8SK 15.1079
366 1YKJ FAD 15.1079
367 1YKJ PHB 15.1079
368 5MBC FMN 15.8273
369 4ZU4 4TG 15.8273
370 3H22 B53 15.8273
371 5LXT GTP 15.8273
372 1QZY TDE 16.5468
373 4ZLU ADP 16.5468
374 4ZLU 4PW 16.5468
375 1H8S AIC 16.5468
376 1QY1 PRZ 17.2662
377 3W68 VIV 17.2662
378 1F5F DHT 17.2662
379 2QL9 CIT 17.5258
380 1OJK GLC BGC 18.705
381 3BXO UPP 18.705
382 4KYS VIB 19.4245
383 3THR C2F 19.4245
384 2IUW AKG 20.1439
385 5GM5 CBI 20.8633
386 4B1M FRU FRU 21.5827
387 1LVG 5GP 23.0216
388 2E27 AB0 23.0216
389 3ACL 3F1 23.741
390 1ODM ASV 24.4604
391 5H9Y BGC BGC BGC BGC 25.8993
392 5IH9 6BF 25.8993
393 1Z0J GTP 27.1186
394 4RD0 GDP 28.0576
395 3TTI KBI 28.777
396 3M3E GAL A2G NPO 29.4964
397 3VV1 GAL FUC 33.813
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