Receptor
PDB id Resolution Class Description Source Keywords
5NGZ 2.4 Å EC: 2.3.2.23 UBE2T IN COMPLEX WITH FRAGMENT EM04 HOMO SAPIENS UBIQUITIN-CONJUGATING ENZYME UBE2T FRAGMENT SCREENING FANCANEMIA PATHWAY DNA REPAIR LIGASE
Ref.: ALLOSTERIC TARGETING OF THE FANCONI ANEMIA UBIQUITIN-CONJUGATING ENZYME UBE2T BY FRAGMENT SCRE J. MED. CHEM. V. 60 4093 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
2BG A:201;
 Valid;
 none;
 Kd = 1.3 mM
164.228 C8 H8 N2 S c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5NGZ 2.4 Å EC: 2.3.2.23 UBE2T IN COMPLEX WITH FRAGMENT EM04 HOMO SAPIENS UBIQUITIN-CONJUGATING ENZYME UBE2T FRAGMENT SCREENING FANCANEMIA PATHWAY DNA REPAIR LIGASE
Ref.: ALLOSTERIC TARGETING OF THE FANCONI ANEMIA UBIQUITIN-CONJUGATING ENZYME UBE2T BY FRAGMENT SCRE J. MED. CHEM. V. 60 4093 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5NGZ Kd = 1.3 mM 2BG C8 H8 N2 S c1ccc2c(c1....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5NGZ Kd = 1.3 mM 2BG C8 H8 N2 S c1ccc2c(c1....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5NGZ Kd = 1.3 mM 2BG C8 H8 N2 S c1ccc2c(c1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 2BG; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 2BG 1 1
2 ABV 0.487805 0.676471
Similar Ligands (3D)
Ligand no: 1; Ligand: 2BG; Similar ligands found: 1365
No: Ligand Similarity coefficient
1 XIY 0.9954
2 1M2 0.9856
3 8ZE 0.9829
4 BCU 0.9824
5 BZ3 0.9775
6 MR1 0.9773
7 N2I 0.9768
8 717 0.9763
9 5XC 0.9753
10 5OB 0.9746
11 F9Y 0.9744
12 H42 0.9744
13 KDV 0.9727
14 ES5 0.9715
15 JB5 0.9713
16 BZ2 0.9705
17 0HN 0.9704
18 03V 0.9695
19 2AQ 0.9695
20 4FS 0.9695
21 ICB 0.9692
22 6NT 0.9676
23 4WL 0.9676
24 JND 0.9676
25 PNZ 0.9675
26 0JD 0.9673
27 ESP 0.9668
28 4P5 0.9657
29 1F1 0.9652
30 NIZ 0.9650
31 COU 0.9648
32 ESX 0.9647
33 OCH 0.9640
34 E5X 0.9639
35 0HO 0.9637
36 8WT 0.9636
37 ISZ 0.9634
38 6NI 0.9625
39 3NY 0.9620
40 BPN 0.9598
41 2ZM 0.9596
42 3A9 0.9595
43 XM0 0.9591
44 5NI 0.9588
45 15N 0.9588
46 6FZ 0.9588
47 CLW 0.9587
48 E1T 0.9582
49 9R5 0.9581
50 FK1 0.9580
51 4FA 0.9579
52 JB8 0.9578
53 ABI 0.9575
54 JDN 0.9575
55 AMH 0.9575
56 11S 0.9574
57 259 0.9573
58 ANN 0.9571
59 2HU 0.9570
60 ES9 0.9570
61 GOJ 0.9569
62 JAW 0.9568
63 J6W 0.9567
64 H4N 0.9565
65 BHO 0.9564
66 94W 0.9563
67 36R 0.9562
68 TPA 0.9562
69 AX7 0.9559
70 JAE 0.9556
71 F4E 0.9554
72 4ZA 0.9553
73 I1E 0.9551
74 ES2 0.9548
75 4JT 0.9546
76 2MI 0.9544
77 MQN 0.9543
78 4NM 0.9542
79 4YO 0.9540
80 CFI 0.9539
81 8NY 0.9538
82 CWJ 0.9537
83 RM1 0.9536
84 0TU 0.9534
85 BNF 0.9534
86 4JQ 0.9534
87 I3A 0.9533
88 SLS 0.9532
89 2HQ 0.9529
90 4BZ 0.9526
91 5MI 0.9525
92 K2T 0.9524
93 1P8 0.9519
94 BSX 0.9519
95 YRL 0.9518
96 TSS 0.9514
97 F60 0.9510
98 J9Q 0.9509
99 5MB 0.9508
100 PEA 0.9507
101 P92 0.9506
102 R9Y 0.9504
103 KOJ 0.9503
104 FBB 0.9501
105 Z82 0.9501
106 ET2 0.9497
107 NPO 0.9496
108 DE5 0.9494
109 TTL 0.9494
110 INO 0.9491
111 BZX 0.9488
112 HA5 0.9488
113 DHR 0.9487
114 9ZE 0.9487
115 SYV 0.9485
116 LDP 0.9484
117 5H1 0.9482
118 PHB 0.9479
119 KJU 0.9478
120 14O 0.9477
121 5VM 0.9474
122 6AI 0.9469
123 7HQ 0.9467
124 2K4 0.9466
125 1P7 0.9457
126 268 0.9457
127 N8Y 0.9456
128 KUF 0.9456
129 270 0.9455
130 PHU 0.9455
131 FEH 0.9455
132 JLZ 0.9455
133 HDH 0.9453
134 NYL 0.9453
135 GLC 0.9450
136 OTR 0.9448
137 ESI 0.9446
138 AHR 0.9445
139 DHB 0.9441
140 E7S 0.9437
141 NNO 0.9435
142 K97 0.9433
143 TGX 0.9432
144 KTW 0.9430
145 5B1 0.9425
146 PZM 0.9425
147 PIM 0.9420
148 FBM 0.9418
149 AEF 0.9415
150 PAB 0.9414
151 PRA 0.9413
152 PIY 0.9413
153 CWS 0.9412
154 MRW 0.9410
155 5WV 0.9410
156 9FL 0.9404
157 SNO 0.9401
158 VGD 0.9400
159 7W4 0.9400
160 FHB 0.9400
161 6KT 0.9397
162 4BY 0.9395
163 JA8 0.9393
164 DIN 0.9392
165 5LA 0.9392
166 HC4 0.9390
167 97T 0.9388
168 PBZ 0.9388
169 4BL 0.9387
170 4A3 0.9382
171 IWT 0.9380
172 173 0.9379
173 GJZ 0.9379
174 J9N 0.9378
175 HBD 0.9377
176 5QY 0.9376
177 5GU 0.9370
178 2HC 0.9370
179 ES7 0.9369
180 XQ0 0.9368
181 HBA 0.9368
182 42A 0.9367
183 FAN 0.9366
184 ASO 0.9366
185 9CA 0.9366
186 TH7 0.9365
187 TYL 0.9362
188 HMH 0.9362
189 IAC 0.9361
190 CTL 0.9361
191 A7W 0.9360
192 4MA 0.9358
193 258 0.9357
194 1Y6 0.9357
195 TCA 0.9357
196 GO2 0.9356
197 CHB 0.9355
198 2HO 0.9354
199 1IT 0.9352
200 NOJ 0.9352
201 6VD 0.9349
202 EYV 0.9349
203 0P6 0.9348
204 HSO 0.9344
205 PZI 0.9344
206 DOB 0.9343
207 069 0.9342
208 4NB 0.9340
209 CXF 0.9337
210 NDH 0.9337
211 RJY 0.9335
212 6RQ 0.9334
213 9FE 0.9333
214 P72 0.9333
215 PBA 0.9333
216 F9P 0.9332
217 IFL 0.9331
218 3Z8 0.9331
219 86J 0.9329
220 Q88 0.9328
221 M3H 0.9326
222 UNJ 0.9325
223 LZM 0.9325
224 PO6 0.9325
225 4NC 0.9324
226 XX2 0.9324
227 ISN 0.9324
228 EUG 0.9323
229 D48 0.9323
230 SHA 0.9322
231 3ZB 0.9316
232 428 0.9316
233 15E 0.9315
234 ODO 0.9314
235 SN4 0.9313
236 FP1 0.9313
237 1L5 0.9313
238 93K 0.9312
239 3HM 0.9310
240 PHE 0.9308
241 8CM 0.9306
242 7W1 0.9306
243 264 0.9305
244 MAJ 0.9303
245 12T 0.9302
246 2LP 0.9302
247 MYJ 0.9301
248 HY1 0.9300
249 KJH 0.9299
250 HX4 0.9297
251 F31 0.9297
252 1A7 0.9296
253 HHI 0.9296
254 1DJ 0.9293
255 KKN 0.9292
256 M2K 0.9291
257 PPY 0.9290
258 6TZ 0.9289
259 4XR 0.9289
260 4HM 0.9288
261 4HC 0.9287
262 J5I 0.9286
263 LNR 0.9285
264 ICO 0.9283
265 1DW 0.9283
266 5RN 0.9282
267 2D0 0.9282
268 RNO 0.9281
269 XBT 0.9281
270 AC6 0.9280
271 3PF 0.9280
272 36E 0.9278
273 OK7 0.9277
274 K34 0.9276
275 MNN 0.9275
276 NF3 0.9275
277 3MB 0.9273
278 0FN 0.9272
279 BEA 0.9270
280 M4T 0.9270
281 CWM 0.9270
282 4VP 0.9270
283 174 0.9268
284 FA0 0.9268
285 BGC 0.9268
286 PXL 0.9267
287 1PT 0.9267
288 OW4 0.9266
289 CPZ 0.9266
290 EVF 0.9265
291 IV2 0.9264
292 7MU 0.9264
293 4LW 0.9264
294 82I 0.9264
295 5NU 0.9263
296 OVM 0.9261
297 5CU 0.9261
298 G3E 0.9260
299 GJP 0.9260
300 CH9 0.9260
301 52C 0.9259
302 HIS 0.9259
303 8HC 0.9257
304 LYL 0.9256
305 G3F 0.9254
306 0FK 0.9253
307 M6N 0.9253
308 0W1 0.9253
309 QWN 0.9252
310 826 0.9252
311 A29 0.9251
312 BHA 0.9251
313 MSR 0.9251
314 2FY 0.9250
315 FK8 0.9249
316 MEW 0.9249
317 HQT 0.9248
318 EA1 0.9247
319 12Q 0.9247
320 8WO 0.9246
321 2EC 0.9246
322 9TW 0.9245
323 SKA 0.9243
324 MS9 0.9243
325 4M0 0.9242
326 NOY 0.9240
327 LQ2 0.9240
328 TT4 0.9240
329 RNS 0.9238
330 PEL 0.9237
331 PAC 0.9236
332 AOT 0.9235
333 J9W 0.9234
334 GCS 0.9232
335 M1Q 0.9231
336 PRY 0.9229
337 42J 0.9229
338 SRO 0.9229
339 NSP 0.9228
340 3R6 0.9228
341 SE2 0.9225
342 HQJ 0.9225
343 2A9 0.9224
344 ES0 0.9224
345 LCN 0.9222
346 VNL 0.9222
347 C2B 0.9221
348 8H8 0.9220
349 92P 0.9217
350 5QX 0.9217
351 FUD 0.9217
352 P9P 0.9216
353 H8N 0.9216
354 8OZ 0.9216
355 45L 0.9215
356 261 0.9215
357 49F 0.9214
358 BZJ 0.9214
359 3DO 0.9212
360 PE0 0.9212
361 A7H 0.9210
362 AJ2 0.9210
363 7VP 0.9207
364 HCI 0.9206
365 QXW 0.9205
366 8W9 0.9205
367 ASC 0.9205
368 FQI 0.9204
369 14J 0.9204
370 J9T 0.9202
371 5RO 0.9200
372 DEE 0.9200
373 4JM 0.9200
374 0FO 0.9199
375 2LY 0.9197
376 M5K 0.9197
377 SNU 0.9196
378 NCT 0.9196
379 A5E 0.9193
380 G2F 0.9192
381 URC 0.9192
382 PH2 0.9191
383 ZBT 0.9191
384 XIZ 0.9191
385 92K 0.9190
386 3ID 0.9190
387 C2Y 0.9190
388 BK9 0.9188
389 Q24 0.9188
390 FYU 0.9188
391 1HN 0.9187
392 AQO 0.9187
393 QMP 0.9187
394 HHR 0.9185
395 24B 0.9185
396 JZ4 0.9182
397 4RU 0.9180
398 0BP 0.9180
399 YPN 0.9179
400 TSR 0.9173
401 L22 0.9172
402 TIU 0.9171
403 JFJ 0.9170
404 RSO 0.9170
405 DMD 0.9169
406 KMY 0.9168
407 PKU 0.9167
408 OVP 0.9166
409 61M 0.9165
410 DNF 0.9165
411 PRZ 0.9163
412 QX4 0.9162
413 DQU 0.9162
414 XAZ 0.9160
415 S8V 0.9160
416 HX3 0.9160
417 ZYR 0.9160
418 TZL 0.9159
419 SW7 0.9158
420 XYL 0.9155
421 RB5 0.9155
422 PJW 0.9155
423 RBJ 0.9154
424 5JQ 0.9153
425 AZ8 0.9152
426 6M9 0.9151
427 5WZ 0.9150
428 EN1 0.9150
429 L14 0.9149
430 4M4 0.9149
431 67N 0.9148
432 R9S 0.9148
433 8S0 0.9148
434 4AA 0.9147
435 KYA 0.9146
436 R8V 0.9145
437 JG8 0.9144
438 C1M 0.9144
439 27B 0.9144
440 2CK 0.9142
441 OW7 0.9142
442 SKM 0.9140
443 MPV 0.9139
444 V55 0.9137
445 ORN 0.9137
446 KT7 0.9136
447 BEZ 0.9136
448 AES 0.9136
449 BNL 0.9134
450 XRG 0.9134
451 L5V 0.9132
452 MWP 0.9132
453 NFM 0.9131
454 46P 0.9131
455 BQ2 0.9130
456 IHB 0.9130
457 M1E 0.9130
458 DS0 0.9127
459 MET 0.9127
460 4XF 0.9126
461 AL0 0.9126
462 BCP 0.9125
463 GAL 0.9125
464 GVG 0.9125
465 FCR 0.9124
466 KTJ 0.9124
467 6N4 0.9123
468 36M 0.9123
469 B62 0.9123
470 E7Z 0.9121
471 TZF 0.9121
472 NPY 0.9120
473 ARP 0.9120
474 44V 0.9118
475 UFO 0.9118
476 OTW 0.9117
477 AN3 0.9117
478 MNM 0.9116
479 M4E 0.9116
480 PRF 0.9116
481 RBL 0.9114
482 M1A 0.9114
483 8XL 0.9114
484 AJV 0.9112
485 VXX 0.9112
486 OGA 0.9112
487 QBM 0.9111
488 XQG 0.9110
489 R8S 0.9110
490 1XM 0.9110
491 0CU 0.9107
492 YH7 0.9107
493 8TX 0.9107
494 I3E 0.9106
495 GZL 0.9106
496 7N0 0.9105
497 NCA 0.9104
498 4Z4 0.9103
499 6ME 0.9102
500 GTQ 0.9100
501 7VS 0.9100
502 3R4 0.9099
503 2AL 0.9099
504 6GU 0.9098
505 4LV 0.9098
506 PEY 0.9096
507 DGJ 0.9096
508 BEN 0.9096
509 N2Z 0.9095
510 3DM 0.9095
511 PBC 0.9095
512 44W 0.9091
513 K7M 0.9090
514 ZXD 0.9090
515 4MU 0.9089
516 QUZ 0.9089
517 IF7 0.9089
518 URO 0.9088
519 P7Y 0.9088
520 HPS 0.9087
521 BTY 0.9086
522 R20 0.9086
523 EXD 0.9086
524 4ME 0.9086
525 4JL 0.9085
526 LT2 0.9084
527 AKG 0.9084
528 MXN 0.9083
529 TSU 0.9081
530 AC0 0.9080
531 M0W 0.9079
532 XHP 0.9079
533 2FQ 0.9078
534 DHY 0.9078
535 AEG 0.9078
536 BOA 0.9076
537 5TY 0.9074
538 L99 0.9074
539 SRT 0.9073
540 CEE 0.9073
541 SX1 0.9072
542 N1E 0.9072
543 H4E 0.9071
544 LPK 0.9071
545 OAA 0.9070
546 PD2 0.9069
547 3XX 0.9069
548 EOL 0.9068
549 FBA 0.9068
550 DRL 0.9066
551 RMN 0.9066
552 F05 0.9066
553 SKF 0.9064
554 0LH 0.9064
555 7MX 0.9064
556 JTH 0.9064
557 0RW 0.9063
558 F0J 0.9063
559 SR1 0.9062
560 4TU 0.9061
561 3BU 0.9061
562 4V2 0.9060
563 0F9 0.9060
564 QBK 0.9060
565 MVN 0.9059
566 BAM 0.9059
567 9DG 0.9058
568 B55 0.9057
569 NTN 0.9057
570 XUL 0.9056
571 6AP 0.9054
572 B40 0.9054
573 3OC 0.9054
574 36Y 0.9052
575 ZZZ 0.9051
576 ONR 0.9051
577 2O6 0.9050
578 DHI 0.9049
579 V1T 0.9048
580 6M4 0.9048
581 X0U 0.9047
582 URS 0.9047
583 S2G 0.9047
584 M0Q 0.9047
585 271 0.9046
586 CXP 0.9046
587 AX3 0.9046
588 6PC 0.9046
589 GO8 0.9045
590 8NX 0.9045
591 SWA 0.9045
592 795 0.9044
593 4VY 0.9044
594 TYR 0.9044
595 H7Y 0.9043
596 AEH 0.9041
597 HMU 0.9041
598 GRO 0.9040
599 2FX 0.9040
600 GAB 0.9040
601 RAT 0.9039
602 GDE 0.9039
603 DYA 0.9038
604 Z5P 0.9037
605 GXY 0.9036
606 JYB 0.9036
607 54G 0.9035
608 2H5 0.9035
609 ZZT 0.9035
610 SAN 0.9035
611 QSB 0.9035
612 XAN 0.9031
613 HH5 0.9031
614 2AK 0.9030
615 T9G 0.9030
616 AH8 0.9029
617 3AE 0.9028
618 AMS 0.9027
619 BDP 0.9026
620 S7J 0.9026
621 2K8 0.9026
622 M45 0.9025
623 XDE 0.9024
624 ALE 0.9024
625 DBX 0.9024
626 5JL 0.9023
627 SOE 0.9023
628 PDC 0.9023
629 4XV 0.9022
630 KMT 0.9021
631 DEW 0.9021
632 68A 0.9021
633 N91 0.9020
634 TH0 0.9020
635 FDB 0.9019
636 AMC 0.9019
637 3H2 0.9018
638 5M0 0.9016
639 5MK 0.9015
640 SOR 0.9015
641 LT1 0.9015
642 XYP 0.9015
643 MO8 0.9014
644 4SX 0.9014
645 NIO 0.9014
646 DHK 0.9013
647 APS 0.9012
648 R2P 0.9011
649 HHS 0.9011
650 DBJ 0.9010
651 75K 0.9010
652 4I8 0.9009
653 FDR 0.9008
654 APZ 0.9007
655 M4S 0.9006
656 SMN 0.9005
657 X0V 0.9005
658 GUN 0.9004
659 D3G 0.9003
660 KTA 0.9003
661 BRT 0.9002
662 3VX 0.8999
663 LYS 0.8999
664 DX4 0.8998
665 HBO 0.8998
666 27Y 0.8998
667 B57 0.8997
668 4FH 0.8997
669 9RW 0.8996
670 TTY 0.8996
671 GCU 0.8996
672 Z13 0.8993
673 4JC 0.8992
674 2HG 0.8991
675 5RG 0.8990
676 TWO 0.8989
677 P80 0.8989
678 S2P 0.8988
679 SHI 0.8988
680 AAS 0.8988
681 SAL 0.8988
682 2F6 0.8987
683 XDK 0.8986
684 PBN 0.8986
685 VOH 0.8986
686 4CS 0.8986
687 WCE 0.8985
688 B85 0.8985
689 P9E 0.8985
690 DHC 0.8984
691 8GC 0.8983
692 PH3 0.8983
693 AZA 0.8982
694 1AL 0.8981
695 OVV 0.8981
696 PQ0 0.8980
697 GNM 0.8980
698 HSM 0.8979
699 NBZ 0.8979
700 A2F 0.8978
701 FBF 0.8976
702 3C4 0.8976
703 Q02 0.8975
704 3U4 0.8975
705 FHC 0.8975
706 GLA 0.8974
707 0R0 0.8974
708 0NX 0.8973
709 TAG 0.8972
710 149 0.8972
711 CK2 0.8970
712 IPB 0.8970
713 YCP 0.8970
714 92G 0.8969
715 VGL 0.8969
716 MUA 0.8968
717 A7N 0.8965
718 3HA 0.8965
719 UNU 0.8965
720 CXH 0.8964
721 HL4 0.8962
722 LGC 0.8962
723 9EW 0.8962
724 AZG 0.8959
725 5XB 0.8959
726 3BZ 0.8958
727 JP2 0.8957
728 EV0 0.8957
729 4J8 0.8956
730 24W 0.8955
731 LR5 0.8954
732 XLS 0.8954
733 3QV 0.8953
734 GLO 0.8953
735 4SV 0.8953
736 4HP 0.8953
737 FF2 0.8952
738 4XS 0.8952
739 3NT 0.8950
740 IOS 0.8950
741 UAN 0.8950
742 JF1 0.8950
743 ALL 0.8947
744 EMZ 0.8946
745 3AB 0.8946
746 QY9 0.8946
747 1LQ 0.8944
748 FE DB1 0.8943
749 S0E 0.8943
750 DBH 0.8941
751 QSH 0.8941
752 MZG 0.8940
753 HLR 0.8940
754 7ME 0.8940
755 SVN 0.8940
756 G4D 0.8939
757 HHH 0.8939
758 CUW 0.8939
759 3F0 0.8938
760 7O4 0.8938
761 4NZ 0.8937
762 COI 0.8936
763 3HB 0.8935
764 EKZ 0.8934
765 MTL 0.8933
766 0W8 0.8933
767 BE2 0.8933
768 JF2 0.8932
769 9MG 0.8931
770 NMJ 0.8931
771 AAN 0.8931
772 SSB 0.8930
773 MLT 0.8930
774 WOO 0.8929
775 1SQ 0.8928
776 BPY 0.8928
777 E35 0.8927
778 KJY 0.8927
779 CFP 0.8926
780 GUA 0.8926
781 RA7 0.8925
782 FGZ 0.8924
783 8IG 0.8924
784 463 0.8924
785 M1H 0.8924
786 5IQ 0.8923
787 LXC 0.8923
788 MWJ 0.8921
789 Y3L 0.8921
790 5HN 0.8921
791 JZ3 0.8920
792 IFM 0.8920
793 GAF 0.8919
794 2FG 0.8919
795 ES1 0.8918
796 HQY 0.8918
797 CFA 0.8917
798 TMG 0.8917
799 HQD 0.8916
800 2BX 0.8916
801 BR9 0.8915
802 JZ2 0.8914
803 EUE 0.8914
804 HHA 0.8913
805 FA1 0.8912
806 4KL 0.8911
807 MEV 0.8911
808 8G0 0.8910
809 39O 0.8910
810 MCT 0.8910
811 8NB 0.8910
812 FBJ 0.8910
813 ADZ 0.8910
814 DHS 0.8910
815 SHG 0.8910
816 O72 0.8909
817 SME 0.8909
818 4CL 0.8908
819 IFP 0.8908
820 EVA 0.8908
821 0N7 0.8906
822 W81 0.8906
823 NAG 0.8905
824 3M0 0.8903
825 6QF 0.8902
826 N5J 0.8902
827 30G 0.8902
828 4JJ 0.8901
829 CLZ 0.8901
830 505 0.8901
831 5JC 0.8900
832 LMR 0.8900
833 N9J 0.8900
834 8U3 0.8900
835 4ZC 0.8900
836 AA 0.8900
837 QX2 0.8899
838 JBH 0.8898
839 PZA 0.8898
840 MD6 0.8897
841 1CO 0.8897
842 ZEC 0.8896
843 GWM 0.8895
844 AZ9 0.8895
845 APG 0.8895
846 M5H 0.8894
847 FBS 0.8894
848 IDM 0.8893
849 9TZ 0.8893
850 YTX 0.8893
851 BDF 0.8892
852 SS1 0.8892
853 2YU 0.8892
854 M58 0.8890
855 GIV 0.8890
856 GLN 0.8890
857 5SG 0.8889
858 B60 0.8889
859 141 0.8888
860 15L 0.8887
861 B53 0.8887
862 5Q0 0.8886
863 4HO 0.8885
864 JPZ 0.8885
865 DPN 0.8885
866 4YS 0.8884
867 M1Z 0.8884
868 AFR 0.8884
869 TIH 0.8884
870 DIE 0.8884
871 MAQ 0.8883
872 DEN 0.8883
873 FDK 0.8882
874 O2A 0.8882
875 XCG 0.8882
876 OKG 0.8881
877 P81 0.8881
878 DFB 0.8881
879 6CS 0.8880
880 XBZ 0.8880
881 53C 0.8880
882 6Q3 0.8879
883 GVY 0.8878
884 N4E 0.8877
885 CN0 0.8876
886 ENO 0.8876
887 5WU 0.8875
888 492 0.8875
889 363 0.8873
890 1Z6 0.8872
891 GXL 0.8872
892 G3H 0.8872
893 G3P 0.8872
894 SYN 0.8872
895 IND 0.8871
896 1MC 0.8871
897 7B4 0.8870
898 HBX 0.8870
899 NLE 0.8869
900 OMD 0.8869
901 RUY 0.8869
902 GYE 0.8869
903 GTR 0.8868
904 3QM 0.8867
905 1QP 0.8867
906 JBK 0.8866
907 VK3 0.8866
908 JKE 0.8866
909 M6W 0.8866
910 51R 0.8866
911 AJY 0.8865
912 NK 0.8865
913 QIV 0.8864
914 JRB 0.8864
915 IGA 0.8864
916 PYF 0.8862
917 1NP 0.8860
918 QSC 0.8860
919 FH2 0.8860
920 BE7 0.8859
921 290 0.8858
922 MPI 0.8858
923 1KP 0.8857
924 HIC 0.8857
925 URF 0.8857
926 ES6 0.8856
927 5MH 0.8856
928 X6X 0.8855
929 K4V 0.8853
930 23J 0.8853
931 MED 0.8852
932 KP6 0.8851
933 FPI 0.8851
934 IT2 0.8850
935 GLT 0.8848
936 X0W 0.8848
937 THA 0.8848
938 ADA 0.8847
939 275 0.8846
940 BZI 0.8846
941 4XH 0.8845
942 42C 0.8843
943 PCA 0.8843
944 KBG 0.8843
945 NQ 0.8841
946 JZ9 0.8841
947 LZ1 0.8840
948 N2M 0.8840
949 2FT 0.8840
950 XYD 0.8839
951 I4B 0.8839
952 NOK 0.8839
953 MAH 0.8839
954 SXS 0.8838
955 NID 0.8837
956 NVU 0.8837
957 2AC 0.8836
958 BML 0.8836
959 OXZ 0.8835
960 LVD 0.8835
961 GZ2 0.8835
962 23A 0.8834
963 PA1 0.8834
964 GF4 0.8834
965 5WY 0.8834
966 1LM 0.8833
967 1DV 0.8831
968 209 0.8831
969 7WG 0.8830
970 13P 0.8830
971 CKA 0.8829
972 GCB 0.8829
973 NLA 0.8828
974 4ZE 0.8828
975 FRU 0.8828
976 TYE 0.8827
977 EGR 0.8827
978 LSQ 0.8827
979 449 0.8827
980 OOG 0.8826
981 OHP 0.8826
982 PQK 0.8823
983 1WG 0.8822
984 2KA 0.8821
985 OA3 0.8821
986 ANF 0.8820
987 JXN 0.8820
988 7WR 0.8819
989 RHU 0.8815
990 ANC 0.8814
991 GCO 0.8814
992 DVQ 0.8812
993 MBG 0.8812
994 Q6T 0.8812
995 3HG 0.8811
996 JXZ 0.8810
997 E1P 0.8810
998 56D 0.8810
999 3IT 0.8810
1000 AGK 0.8810
1001 S24 0.8809
1002 GLU 0.8809
1003 1GN 0.8808
1004 K82 0.8807
1005 152 0.8807
1006 YZM 0.8807
1007 7WV 0.8807
1008 QOS 0.8806
1009 2CZ 0.8805
1010 HH8 0.8804
1011 A1U 0.8804
1012 DRG 0.8803
1013 GVH 0.8803
1014 7NI 0.8802
1015 RD4 0.8802
1016 HDL 0.8802
1017 DMJ 0.8800
1018 M6Z 0.8800
1019 AY4 0.8800
1020 4JU 0.8800
1021 2CQ 0.8799
1022 34A 0.8798
1023 IDH 0.8797
1024 45C 0.8796
1025 TLA 0.8795
1026 PMF 0.8793
1027 1WD 0.8793
1028 1SA 0.8793
1029 ACA 0.8789
1030 MWM 0.8788
1031 PYD 0.8786
1032 ICP 0.8786
1033 5GT 0.8786
1034 BPW 0.8786
1035 INE 0.8786
1036 LKA 0.8785
1037 H5B 0.8784
1038 TDR 0.8784
1039 E3D 0.8782
1040 2MH 0.8782
1041 Y8I 0.8781
1042 MQB 0.8781
1043 3SK 0.8781
1044 ABN 0.8781
1045 28N 0.8781
1046 BZF 0.8780
1047 HFA 0.8780
1048 7ZE 0.8779
1049 4CM 0.8779
1050 2QC 0.8779
1051 2MP 0.8778
1052 N7I 0.8777
1053 RXA 0.8776
1054 HPP 0.8776
1055 TXW 0.8775
1056 86L 0.8775
1057 0R1 0.8773
1058 PXM 0.8773
1059 DX3 0.8773
1060 ASP 0.8772
1061 344 0.8771
1062 F12 0.8771
1063 C9E 0.8770
1064 DIU 0.8770
1065 MAN 0.8770
1066 5VL 0.8770
1067 PPT 0.8769
1068 0XT 0.8768
1069 NFA 0.8768
1070 RIB 0.8768
1071 CIY 0.8767
1072 BDI 0.8767
1073 UEG 0.8767
1074 4HS 0.8767
1075 FIX 0.8766
1076 535 0.8765
1077 PY7 0.8765
1078 Q71 0.8765
1079 JBZ 0.8764
1080 G5V 0.8764
1081 XQI 0.8764
1082 0CT 0.8760
1083 SVD 0.8760
1084 HPA 0.8759
1085 PFB 0.8758
1086 EYK 0.8757
1087 DNA 0.8756
1088 K5W 0.8756
1089 BIK 0.8755
1090 DGN 0.8755
1091 GGL 0.8754
1092 WBU 0.8753
1093 SD4 0.8753
1094 43M 0.8753
1095 HKD 0.8751
1096 HSE 0.8751
1097 PYQ 0.8750
1098 F69 0.8749
1099 1XA 0.8748
1100 150 0.8747
1101 FB2 0.8747
1102 F81 0.8745
1103 AZM 0.8745
1104 3HP 0.8742
1105 GIF 0.8742
1106 H76 0.8741
1107 KMH 0.8740
1108 HNL 0.8739
1109 X09 0.8739
1110 HNK 0.8739
1111 MAE 0.8739
1112 HA7 0.8738
1113 ROI 0.8738
1114 3N1 0.8738
1115 Q07 0.8737
1116 H33 0.8736
1117 32X 0.8736
1118 TZM 0.8736
1119 F06 0.8736
1120 B5D 0.8736
1121 7MW 0.8735
1122 282 0.8734
1123 DGL 0.8734
1124 2IT 0.8734
1125 4JP 0.8734
1126 HNT 0.8734
1127 9X7 0.8733
1128 1U6 0.8733
1129 IUR 0.8730
1130 6FB 0.8730
1131 HT4 0.8729
1132 YIO 0.8727
1133 PXY 0.8725
1134 3AL 0.8724
1135 5OO 0.8720
1136 7B3 0.8719
1137 BNS 0.8719
1138 VNJ 0.8719
1139 BP9 0.8718
1140 X48 0.8716
1141 P4B 0.8716
1142 SG2 0.8715
1143 DA4 0.8714
1144 L3Q 0.8714
1145 49O 0.8714
1146 PEP 0.8714
1147 SJ5 0.8713
1148 CIT 0.8712
1149 DFU 0.8711
1150 HCS 0.8711
1151 TM7 0.8709
1152 3SL 0.8709
1153 1P3 0.8709
1154 QPR 0.8708
1155 4JN 0.8708
1156 HQE 0.8708
1157 2GS 0.8707
1158 54X 0.8707
1159 FPY 0.8706
1160 4CH 0.8706
1161 UFV 0.8706
1162 6DP 0.8705
1163 091 0.8703
1164 C82 0.8702
1165 F4K 0.8701
1166 OHJ 0.8701
1167 1WC 0.8700
1168 3WA 0.8700
1169 AKH 0.8700
1170 OHG 0.8700
1171 5UC 0.8698
1172 PMB 0.8698
1173 9BF 0.8698
1174 FA3 0.8698
1175 AM4 0.8697
1176 5WX 0.8697
1177 ORO 0.8697
1178 3MG 0.8696
1179 QWW 0.8695
1180 JBE 0.8695
1181 TC7 0.8694
1182 CSN 0.8693
1183 FB1 0.8693
1184 QMS 0.8691
1185 CCU 0.8691
1186 286 0.8690
1187 F2W 0.8690
1188 JBQ 0.8689
1189 3FH 0.8688
1190 BTE 0.8686
1191 N3W 0.8686
1192 2CL 0.8686
1193 PGH 0.8685
1194 K3Q 0.8685
1195 JF6 0.8683
1196 G14 0.8683
1197 DPZ 0.8680
1198 PFL 0.8679
1199 B2J 0.8679
1200 M2H 0.8678
1201 TOF 0.8677
1202 GDL 0.8676
1203 1DU 0.8676
1204 N0Z 0.8675
1205 RIP 0.8674
1206 FOT 0.8674
1207 1MR 0.8673
1208 BP7 0.8673
1209 FUL 0.8672
1210 DNC 0.8671
1211 DHQ 0.8671
1212 SEP 0.8670
1213 C2A 0.8670
1214 IOL 0.8669
1215 3J8 0.8669
1216 6HO 0.8669
1217 TZE 0.8669
1218 TRP 0.8669
1219 MP5 0.8668
1220 3VQ 0.8668
1221 ST3 0.8666
1222 QIC 0.8666
1223 XXG 0.8665
1224 BZE 0.8664
1225 FBW 0.8664
1226 TLD 0.8663
1227 AMR 0.8662
1228 3PG 0.8661
1229 BMA 0.8661
1230 ADE 0.8660
1231 4JE 0.8660
1232 3Z7 0.8660
1233 20J 0.8660
1234 4JO 0.8659
1235 FLC 0.8658
1236 SYE 0.8656
1237 ODK 0.8654
1238 2XX 0.8652
1239 DTL 0.8651
1240 293 0.8650
1241 AMQ 0.8649
1242 GRE 0.8648
1243 DOR 0.8648
1244 EQT 0.8645
1245 5NE 0.8645
1246 6M1 0.8644
1247 B56 0.8643
1248 25R 0.8642
1249 1BN 0.8641
1250 K17 0.8641
1251 10L 0.8640
1252 TEO 0.8640
1253 DQA 0.8640
1254 PUE 0.8640
1255 FBV 0.8639
1256 NDM 0.8638
1257 37T 0.8637
1258 M78 0.8636
1259 NPA 0.8636
1260 PCR 0.8636
1261 FUC 0.8636
1262 JZ5 0.8635
1263 CTS 0.8634
1264 LG4 0.8634
1265 NDG 0.8634
1266 6ZX 0.8633
1267 H62 0.8632
1268 I2E 0.8632
1269 2JK 0.8632
1270 OXC 0.8632
1271 ZZA 0.8631
1272 C2U 0.8630
1273 VKC 0.8630
1274 GLY GLY 0.8627
1275 T6C 0.8626
1276 4NS 0.8625
1277 GLL 0.8623
1278 LDU 0.8622
1279 SMV 0.8621
1280 8K2 0.8620
1281 KBB 0.8620
1282 AZF 0.8617
1283 PLQ 0.8616
1284 KBZ 0.8615
1285 R2B 0.8613
1286 NBE 0.8612
1287 M3E 0.8610
1288 7CZ 0.8610
1289 9KT 0.8609
1290 D2G 0.8609
1291 XCZ 0.8608
1292 7WA 0.8607
1293 HRM 0.8606
1294 GZ3 0.8603
1295 9AP 0.8602
1296 G12 0.8602
1297 9DA 0.8602
1298 JZ1 0.8602
1299 27K 0.8601
1300 8GK 0.8598
1301 UY7 0.8598
1302 GAG 0.8597
1303 0MK 0.8597
1304 FPN 0.8597
1305 6MP 0.8595
1306 OQC 0.8595
1307 6F0 0.8594
1308 R8A 0.8593
1309 E3X 0.8592
1310 4MB 0.8592
1311 XYS 0.8592
1312 UNC 0.8591
1313 SS2 0.8591
1314 IOP 0.8590
1315 495 0.8590
1316 95Z 0.8590
1317 7HP 0.8587
1318 MT0 0.8587
1319 TBS 0.8585
1320 PFF 0.8582
1321 ZME 0.8581
1322 9HX 0.8580
1323 7I2 0.8580
1324 LDR 0.8575
1325 PCS 0.8575
1326 2PG 0.8575
1327 PRO 0.8574
1328 IJZ 0.8573
1329 SWD 0.8569
1330 DA1 0.8569
1331 J1Z 0.8569
1332 HYP 0.8567
1333 7MH 0.8566
1334 6R8 0.8565
1335 ES4 0.8563
1336 1VK 0.8560
1337 6L6 0.8560
1338 NK2 0.8557
1339 PG3 0.8554
1340 GBD 0.8552
1341 BP1 0.8550
1342 TBP 0.8549
1343 Q7A 0.8549
1344 ZZ3 0.8545
1345 SYA 0.8544
1346 34D 0.8543
1347 HPT 0.8540
1348 9UL 0.8540
1349 2ZV 0.8539
1350 ARB 0.8539
1351 6NA 0.8538
1352 0TR 0.8536
1353 HQ9 0.8536
1354 B4O 0.8535
1355 SHO 0.8535
1356 PM6 0.8535
1357 NGT 0.8534
1358 NGO 0.8533
1359 549 0.8529
1360 JU2 0.8525
1361 AW5 0.8525
1362 1XN 0.8523
1363 S76 0.8519
1364 LAO 0.8514
1365 7A2 0.8513
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5NGZ; Ligand: 2BG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5ngz.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
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