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Receptor
PDB id Resolution Class Description Source Keywords
5N5D 1.55 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE O-METHYLTRANSFERASE TOMG FROM STREP ACHROMOGENES INVOLVED IN TOMAYMYCIN SYNTHESIS IN COMPLEX WI STREPTOMYCES REGENSIS O-METHYLTRANSFERASE TOMAYMYCIN ROSSMANN-LIKE FOLD S-ADENOMETHIONINE TRANSFERASE
Ref.: TOTAL BIOSYNTHESIS OF THE PYRROLO[4,2]BENZODIAZEPIN SCAFFOLD TOMAYMYCIN ON AN IN VITRO RECONSTITUTED NR SYSTEM. CELL CHEM BIOL V. 24 1216 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 B:304;
B:306;
B:305;
A:308;
A:307;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
GOL A:304;
A:305;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SAM A:306;
B:303;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
BU3 A:302;
B:302;
A:303;
A:301;
B:301;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
90.121 C4 H10 O2 C[C@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5N5D 1.55 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE O-METHYLTRANSFERASE TOMG FROM STREP ACHROMOGENES INVOLVED IN TOMAYMYCIN SYNTHESIS IN COMPLEX WI STREPTOMYCES REGENSIS O-METHYLTRANSFERASE TOMAYMYCIN ROSSMANN-LIKE FOLD S-ADENOMETHIONINE TRANSFERASE
Ref.: TOTAL BIOSYNTHESIS OF THE PYRROLO[4,2]BENZODIAZEPIN SCAFFOLD TOMAYMYCIN ON AN IN VITRO RECONSTITUTED NR SYSTEM. CELL CHEM BIOL V. 24 1216 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 5N5D - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 5N5D - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 5N5D - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5N5D; Ligand: SAM; Similar sites found with APoc: 937
This union binding pocket(no: 1) in the query (biounit: 5n5d.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1QAN SAH None
2 1IM8 SAI None
3 2HMT NAI None
4 3CIF NAD None
5 3CIF G3H None
6 2FKA BEF None
7 1J5P NAD None
8 4RDN 6MD None
9 1FWV SGA MAG FUC None
10 6FX2 FUC C4W NAG BMA MAN NAG GAL None
11 2BOS GLA GAL GLC None
12 2BOS GLA GAL GLC NBU None
13 3N7S 3N7 None
14 4UCI SAM 0.884956
15 1EXF GLY 0.884956
16 1OC2 TDX 0.884956
17 1OC2 NAD 0.884956
18 1XHL NDP 0.884956
19 3BGD SAH 1.32743
20 2EG5 SAH 1.32743
21 3BGD PM6 1.32743
22 1XSE NDP 1.32743
23 3GGO NAI 1.32743
24 3GGO ENO 1.32743
25 1Z6Z NAP 1.32743
26 1U1I NAD 1.32743
27 1WY7 SAH 1.44928
28 3FZG SAM 1.5
29 2XVM SAH 1.50754
30 1RP0 AHZ 1.76991
31 4NTD FAD 1.76991
32 5OJI ISN 1.76991
33 5OJI NAP 1.76991
34 3G5S FAD 1.76991
35 5FWA J7C 1.76991
36 1LTH NAD 1.88088
37 1DCP HBI 1.92308
38 1SQL GUN 2.05479
39 3FPF TNA 2.21239
40 3FPF MTA 2.21239
41 3C6K SPD 2.21239
42 2NXE SAM 2.21239
43 6GAR FAD 2.21239
44 3C6K MTA 2.21239
45 5I39 FAD 2.21239
46 5BJX NAD 2.21239
47 5BJX UDP 2.21239
48 5L95 AMP 2.21239
49 1BDB NAD 2.21239
50 5WKC FAD 2.21239
51 1T9D 1MM 2.21239
52 1T9D PYD 2.21239
53 3ELW GP3 2.21239
54 3ELW SAM 2.21239
55 3H8V ATP 2.21239
56 1T9D P25 2.21239
57 1T9D FAD 2.21239
58 5AHO TLA 2.21239
59 3GCZ SAM 2.21239
60 3EVF GTA 2.21239
61 3EVF SAH 2.21239
62 2EWM NAD 2.21239
63 2RGH FAD 2.21239
64 3NUG NAD 2.21239
65 2FZW NAD 2.21239
66 5EOW FAD 2.21239
67 3FG2 FAD 2.21239
68 3ETG GTP 2.21239
69 3ETG GLU 2.21239
70 5GUD 2IT 2.21239
71 4G5H NAP 2.21239
72 4G5H UD7 2.21239
73 5GUD NDP 2.21239
74 5GT9 NAP 2.21239
75 3RFV NAI 2.21239
76 3O9Z NAD 2.21239
77 2DFV NAD 2.21239
78 3O9Z AKG 2.21239
79 3GFB NAD 2.21239
80 1RJD SAM 2.21239
81 1T9D P22 2.21239
82 3ETG NDP 2.21239
83 3WV8 ATP 2.29358
84 4X7Y SAH 2.65487
85 1Q0S SAH 2.65487
86 3TLJ SAH 2.65487
87 1JQ3 AAT 2.65487
88 1ZK7 FAD 2.65487
89 4FZV SAM 2.65487
90 5KOK SAH 2.65487
91 3NYC FAD 2.65487
92 3NYC IAR 2.65487
93 5KMS NAD 2.65487
94 4YAG NAI 2.65487
95 2Q28 ADP 2.65487
96 5KOK S9T 2.65487
97 2FK8 SAM 2.65487
98 4USR FAD 2.65487
99 2CDU FAD 2.65487
100 5KOK R9T 2.65487
101 5MZI FAD 2.65487
102 5MZI FYK 2.65487
103 5Y77 FAD 2.65487
104 6GKV SAH 2.65487
105 2E5V FAD 2.65487
106 5M67 NAD 2.65487
107 5KMS FAD 2.65487
108 5M67 ADE 2.65487
109 4FWE FAD 2.65487
110 3O03 NAP 2.65487
111 5M67 3D1 2.65487
112 2IID FAD 2.65487
113 2IID PHE 2.65487
114 5THQ NDP 2.65487
115 1J0X NAD 2.65487
116 1PZG A3D 2.65487
117 1E5Q NDP 2.65487
118 1LDN NAD 2.65487
119 3CTY FAD 2.65487
120 1R6D NAD 2.65487
121 3LU1 NAD 2.65487
122 1R6D DAU 2.65487
123 2CDU ADP 2.65487
124 5DF1 58X 2.65487
125 5DF1 NAP 2.65487
126 1M2K APR 2.65487
127 3B1F NAD 2.65487
128 1AE1 NAP 2.65487
129 1E3I CXF 2.65487
130 3O7W SAM 2.65487
131 5FTW SAH 2.65487
132 4O0L NDP 2.65487
133 4P83 U5P 2.74725
134 2BZ1 TAU 3.06122
135 2WK1 SAH 3.09735
136 3SQP FAD 3.09735
137 2HQM FAD 3.09735
138 3S5W FAD 3.09735
139 3X0D SAH 3.09735
140 1NV8 SAM 3.09735
141 4IWN GEK 3.09735
142 1NV8 MEQ 3.09735
143 5CUQ NSC 3.09735
144 2C31 ADP 3.09735
145 2C31 TZD 3.09735
146 2XVE FAD 3.09735
147 3GF4 UPG 3.09735
148 3GF4 FAD 3.09735
149 4BV6 FAD 3.09735
150 2XVF FAD 3.09735
151 3FPZ AHZ 3.09735
152 2C7G ODP 3.09735
153 2C7G FAD 3.09735
154 1YBH FAD 3.09735
155 2NVK FAD 3.09735
156 4FN4 NAD 3.09735
157 4NTC FAD 3.09735
158 3NJ4 AFX 3.09735
159 3NJ4 NAD 3.09735
160 3NDJ JHZ 3.09735
161 3NDJ SAH 3.09735
162 5O4J 9KH 3.09735
163 3AYI FAD 3.09735
164 3AYI HCI 3.09735
165 5O4J PJL 3.09735
166 5O4J SAH 3.09735
167 1RM0 D6P 3.09735
168 1RM0 NAI 3.09735
169 3T31 DCQ 3.09735
170 3T31 FAD 3.09735
171 2GDZ NAD 3.09735
172 2WA2 SAM 3.09735
173 4EIP FAD 3.09735
174 1V8B NAD 3.09735
175 2NVK NAP 3.09735
176 2FR1 NDP 3.09735
177 4RDH AMP 3.09735
178 4RDI ATP 3.09735
179 2BZG SAH 3.09735
180 4CQM NAP 3.09735
181 4CM9 NAP 3.09735
182 1SB8 UD2 3.09735
183 1SB8 NAD 3.09735
184 1H2B NAJ 3.09735
185 5XWC 8GL 3.09735
186 5XWC NAP 3.09735
187 5XWC 2IT 3.09735
188 2VZ0 D64 3.09735
189 2VZ0 NAP 3.09735
190 3WLE NAD 3.09735
191 5K6A NAP 3.09735
192 3GMB FAD 3.09735
193 3BMN NAP 3.09735
194 4CMI NAP 3.09735
195 1X7D ORN 3.09735
196 5JY6 NAD 3.09735
197 4CLO NAP 3.09735
198 3JQ8 NAP 3.09735
199 2WD7 NAP 3.09735
200 3JQ7 NAP 3.09735
201 5JCJ NAP 3.09735
202 2AJH MET 3.09735
203 3RG9 NDP 3.09735
204 1A5Z NAD 3.09735
205 4CLR NAP 3.09735
206 5JDC NAP 3.09735
207 3JQA NAP 3.09735
208 4CM8 NAP 3.09735
209 3JQB NAP 3.09735
210 4CME NAP 3.09735
211 3BMO NAP 3.09735
212 3JQ9 NAP 3.09735
213 4CM4 NAP 3.09735
214 4BVA NDP 3.09735
215 1X7D NAD 3.09735
216 5JDI NAP 3.09735
217 3JQG NAP 3.09735
218 4A6D SAM 3.09735
219 4BVA T3 3.09735
220 3JQF NAP 3.09735
221 3BMQ NAP 3.09735
222 3U31 NAD 3.09735
223 6DUB SAH 3.15315
224 4HSU FAD 3.22581
225 1X14 NAD 3.2419
226 2PXX SAH 3.25581
227 2VT3 ATP 3.25581
228 1DJL NAP 3.38164
229 3GRU AMP 3.53982
230 2ZIF SAM 3.53982
231 4BLW AMP 3.53982
232 5JAQ NAI 3.53982
233 6ARJ SAH 3.53982
234 6ARJ BW4 3.53982
235 5DXA SFG 3.53982
236 4BLW SAH 3.53982
237 5DX1 SFG 3.53982
238 5DX8 SFG 3.53982
239 5DWQ SFG 3.53982
240 5E1M PRO PRO LYS ARG ILE ALA 3.53982
241 5E1M SAH 3.53982
242 4YJK URA 3.53982
243 1LVL FAD 3.53982
244 1G60 SAM 3.53982
245 3AB1 FAD 3.53982
246 2R4J 13P 3.53982
247 2R4J FAD 3.53982
248 2YVF FAD 3.53982
249 2YVF NAD 3.53982
250 5DX0 SFG 3.53982
251 3VC1 SAH 3.53982
252 3VC1 GST 3.53982
253 3GU3 SAH 3.53982
254 1GPE FAD 3.53982
255 2YVJ FAD 3.53982
256 5K0A FAD 3.53982
257 4ZCC FAD 3.53982
258 4ZCC NAI 3.53982
259 1LVL NAD 3.53982
260 5KOX FAD 3.53982
261 5KOX RFP 3.53982
262 1RSG FAD 3.53982
263 1KPG SAH 3.53982
264 5UR0 NAD 3.53982
265 4GKV NAD 3.53982
266 4HXY NDP 3.53982
267 1T26 GBD 3.53982
268 1T26 NAI 3.53982
269 6DEN FAD 3.53982
270 6DEN G8A 3.53982
271 6DEN TP9 3.53982
272 5W7K SAH 3.53982
273 1G0N NDP 3.53982
274 1G0N PHH 3.53982
275 1GR0 NAD 3.53982
276 2A14 SAH 3.53982
277 3H9E NAD 3.53982
278 6F7L FAD 3.53982
279 1LLU NAD 3.53982
280 3CMC NAD 3.53982
281 3P9C SAH 3.53982
282 6IS0 SAH 3.53982
283 5GWT NAD 3.53982
284 1Q19 SSC 3.53982
285 4J4H NAI 3.53982
286 4J4H 1J1 3.53982
287 5GWT SIN 3.53982
288 5T2U NAP 3.53982
289 3WMX NAD 3.53982
290 2PS1 ORO 3.53982
291 1GAD NAD 3.53982
292 2VYN NAD 3.53982
293 3H4V DVP 3.53982
294 3H4V NAP 3.53982
295 3NTA FAD 3.65854
296 1Z3C SA8 3.69128
297 3NTD FAD 3.71681
298 1R6N 434 3.79147
299 1D4O NAP 3.80435
300 1U8X NAD 3.81356
301 3NT6 FAD 3.83275
302 4QTU SAM 3.84615
303 1EJ0 SAM 3.88889
304 3GDH SAH 3.9823
305 1V59 FAD 3.9823
306 1D4D FAD 3.9823
307 4PIO SAH 3.9823
308 4PIO AVI 3.9823
309 4MOP 2H5 3.9823
310 1ELI PYC 3.9823
311 2IZ1 ATR 3.9823
312 5HSA FAS 3.9823
313 3E1T FAD 3.9823
314 5HJM MTA 3.9823
315 4YNU LGC 3.9823
316 4YNU FAD 3.9823
317 5FJN BE2 3.9823
318 5FJN FAD 3.9823
319 1V59 NAD 3.9823
320 4OPC PGT 3.9823
321 4OPC FDA 3.9823
322 3UOY FAD 3.9823
323 3UOY NAP 3.9823
324 2Q7V FAD 3.9823
325 2RGJ FAD 3.9823
326 5OC1 FAD 3.9823
327 4J56 FAD 3.9823
328 3CH6 NAP 3.9823
329 3CH6 311 3.9823
330 3GD4 FAD 3.9823
331 3GD4 NAD 3.9823
332 5DLY 5D7 3.9823
333 5DLY SAH 3.9823
334 1KPH SAH 3.9823
335 1YY5 FAD 3.9823
336 3EGI ADP 3.9823
337 2P41 SAH 3.9823
338 5J60 FAD 3.9823
339 5E9W SAH 3.9823
340 3LCC SAH 3.9823
341 2VVL FAD 3.9823
342 3V1Y NAD 3.9823
343 4Z0H NAD 3.9823
344 2GN4 NDP 3.9823
345 3ZV6 4HB 3.9823
346 3ZV6 NAD 3.9823
347 3EVG SAH 3.9823
348 2VVM FAD 3.9823
349 2GN4 UD1 3.9823
350 1FUR MLT 3.9823
351 3OID NDP 3.9823
352 1S7G APR 3.9823
353 1KEW NAD 3.9823
354 2HJR APR 3.9823
355 2Q0L FAD 3.9823
356 5A3B APR 3.9823
357 5FEU NAP 3.9823
358 4LHD GLY 3.9823
359 2JHF NAD 3.9823
360 3RKR NAP 3.9823
361 5FFF 5XC 3.9823
362 4YAC NAI 3.9823
363 1C0I BE2 3.9823
364 1C0I FAD 3.9823
365 1S7G NAD 3.9823
366 3H5N ATP 3.9823
367 5FFF NAP 3.9823
368 6AA8 NAD 3.9823
369 5N0J FAD 3.9886
370 5TWB FAD 4.06977
371 4USQ FAD 4.15512
372 5YEC ATP 4.20168
373 3WDM ADN 4.21456
374 2O07 SPD 4.27632
375 2O07 MTA 4.27632
376 2FWP ICR 4.37158
377 3QOX SAH 4.42478
378 1G55 SAH 4.42478
379 5MW4 5JU 4.42478
380 5BVA FAD 4.42478
381 5X62 SAH 4.42478
382 3CGD COA 4.42478
383 2YX1 SFG 4.42478
384 4X9M FAD 4.42478
385 3HDY FAD 4.42478
386 3HDY GDU 4.42478
387 3HDY FDA 4.42478
388 3CGD FAD 4.42478
389 5ZYN FAD 4.42478
390 6H3O FAD 4.42478
391 3CGD NAD 4.42478
392 4AT0 FAD 4.42478
393 3CGB FAD 4.42478
394 4DCM SAM 4.42478
395 5TS5 FAD 4.42478
396 5JCM FAD 4.42478
397 5JCM ISD 4.42478
398 5JCM NAD 4.42478
399 2A92 NAI 4.42478
400 5HXI FAD 4.42478
401 5HXI 5HN 4.42478
402 4JNA FAD 4.42478
403 5W7M SAH 4.42478
404 5D4V SAH 4.42478
405 3QWI NAP 4.42478
406 3QWI CUE 4.42478
407 5XWV NDP 4.42478
408 2OBF SAH 4.42478
409 5XWV 8H6 4.42478
410 5TOW ADN 4.42478
411 5TOW NAI 4.42478
412 2OBF F83 4.42478
413 4D79 ATP 4.42478
414 6CDZ CB3 4.42478
415 1RJW ETF 4.42478
416 3WGT QSC 4.42478
417 3WGT FAD 4.42478
418 3AFN NAP 4.42478
419 5MLR GRQ 4.42478
420 5MLR NAP 4.42478
421 5N6C NAD 4.42478
422 3L4S NAD 4.42478
423 3L4S 3PG 4.42478
424 1GPM AMP 4.42478
425 1AOE NDP 4.42478
426 1AOE GW3 4.42478
427 4ZRN UPG 4.48718
428 4ZRN NAD 4.48718
429 1BXK NAD 4.50704
430 5EJ2 NAD 4.54545
431 4J36 FAD 4.57831
432 4J36 1HR 4.57831
433 4YUW S4M 4.60526
434 4YUW 4JU 4.60526
435 5Z21 NAI 4.7486
436 3PT9 SAH 4.86726
437 4M73 SAH 4.86726
438 4R6W PC 4.86726
439 4R6W SAH 4.86726
440 4M73 M72 4.86726
441 4JDR FAD 4.86726
442 6GFK SAH 4.86726
443 6FDF SAH 4.86726
444 4HA6 FAD 4.86726
445 4RPL 3UC 4.86726
446 4RPL FAD 4.86726
447 6B92 SAH 4.86726
448 1I8T FAD 4.86726
449 2Z3Y F2N 4.86726
450 1PR9 NAP 4.86726
451 1YKJ PHB 4.86726
452 1YKJ FAD 4.86726
453 4REP FAD 4.86726
454 5NMX FAD 4.86726
455 4MIG G3F 4.86726
456 5NMX NAP 4.86726
457 1P77 ATR 4.86726
458 4RSL FAD 4.86726
459 3D3W NAP 4.86726
460 1JQD SAH 4.86726
461 2B4R NAD 4.86726
462 6FHO FAD 4.86726
463 2B4R AES 4.86726
464 2AOT SAH 4.86726
465 2DTX BMA 4.86726
466 4Y9D NAI 4.86726
467 4KGD FAD 4.86726
468 4KGD TDP 4.86726
469 2G5C NAD 4.86726
470 2IXB A2G 4.86726
471 1SAY PYR 4.86726
472 1DJN ADP 4.86726
473 3SJ7 NDP 4.86726
474 2IXB NAD 4.86726
475 1NVM NAD 4.86726
476 6EL3 NAP 4.86726
477 1NJR XYL 4.86726
478 5MB4 NAG 4.86726
479 5MB4 NDG 4.86726
480 2V6G NAP 4.86726
481 1GQ2 NAP 4.86726
482 1DMR PGD 4.86726
483 5EEH SAH 4.86726
484 5EEH P9P 4.86726
485 4PIV NDP 4.86726
486 5N53 8NB 5.12821
487 2DPM SAM 5.30973
488 3RNM FAD 5.30973
489 5J5Z FAD 5.30973
490 1YQZ FAD 5.30973
491 4B63 ORN 5.30973
492 4B63 NAP 5.30973
493 4B63 FAD 5.30973
494 1Y8Q ATP 5.30973
495 3ICT FAD 5.30973
496 3ICS FAD 5.30973
497 3ICR FAD 5.30973
498 2Q1S NAI 5.30973
499 1H82 GZZ 5.30973
500 1H82 FAD 5.30973
501 5TTJ FAD 5.30973
502 4Z24 FAD 5.30973
503 3ICS ADP 5.30973
504 3ICT ADP 5.30973
505 6ER9 NAP 5.30973
506 6ER9 FAD 5.30973
507 3QPB URA 5.30973
508 5F7J ADE 5.30973
509 4D42 NAP 5.30973
510 4D42 W0I 5.30973
511 5UAO FAD 5.30973
512 1K3T BRZ 5.30973
513 1MXH NAP 5.30973
514 2HIM ASN 5.30973
515 1MXH DHF 5.30973
516 5Z2F NAP 5.30973
517 1PL6 572 5.30973
518 1PL6 NAD 5.30973
519 2F1K NAP 5.30973
520 3OFK SAH 5.55556
521 3Q87 SAM 5.6
522 5U8U FAD 5.75221
523 4ONQ SFG 5.75221
524 4M52 FAD 5.75221
525 2VDV SAM 5.75221
526 2DKH FAD 5.75221
527 5WGR FAD 5.75221
528 2JHP SAH 5.75221
529 2DKH 3HB 5.75221
530 4YRY FAD 5.75221
531 4IV9 FAD 5.75221
532 4YRY NAD 5.75221
533 2A8X FAD 5.75221
534 6D6Y SAH 5.75221
535 4M52 M52 5.75221
536 2Q1W NAD 5.75221
537 3M6W SAM 5.75221
538 1Q1R FAD 5.75221
539 1RYI GOA 5.75221
540 5EZ7 FAD 5.75221
541 1ZEM NAD 5.75221
542 1RYI FAD 5.75221
543 4NBU NAI 5.75221
544 2BD0 NAP 5.75221
545 6DNT NAD 5.75221
546 1VKO NAD 5.75221
547 1IY8 NAD 5.75221
548 2AE2 PTO 5.75221
549 5WUW NAP 5.75221
550 2AE2 NAP 5.75221
551 4UP4 GAL NAG 5.75221
552 1U3U NAD 5.75221
553 1U3U BNF 5.75221
554 3OA2 NAD 5.75221
555 3KIH GDL 6.18557
556 3FUU ADN 6.19469
557 1COY FAD 6.19469
558 5THY SAH 6.19469
559 2JJQ SAH 6.19469
560 1COY AND 6.19469
561 3IHG FAD 6.19469
562 5EB4 FAD 6.19469
563 4AP3 NAP 6.19469
564 4AP3 FAD 6.19469
565 4L2I FAD 6.19469
566 1KNR FAD 6.19469
567 3NKS FAD 6.19469
568 4PLG NAI 6.19469
569 4PLG OXM 6.19469
570 2ZXI FAD 6.19469
571 3VPH NAD 6.19469
572 1I2B NAD 6.19469
573 1I2B USQ 6.19469
574 1I2B UPG 6.19469
575 3VPH OXM 6.19469
576 5NA1 FAD 6.19469
577 4D5G FAD 6.19469
578 4D5G TPP 6.19469
579 1EWK GLU 6.19469
580 1OAA OAA 6.19469
581 1SC6 NAD 6.19469
582 1Q0H FOM 6.19469
583 1Q0H NDP 6.19469
584 6GNA FAD 6.19469
585 3DXY SAM 6.42202
586 3OZ2 FAD 6.54912
587 4DMG SAM 6.63717
588 1N2X SAM 6.63717
589 5X68 FAD 6.63717
590 1NW5 SAM 6.63717
591 1REO FAD 6.63717
592 2GMH FAD 6.63717
593 1GZ6 NAI 6.63717
594 2AQJ FAD 6.63717
595 2AQJ TRP 6.63717
596 1BC5 SAH 6.63717
597 1D1T NAD 6.63717
598 5OJ7 AR6 6.63717
599 3GWZ SAH 7.04607
600 1XCL SAH 7.07965
601 1U2Z SAH 7.07965
602 1P1C SAH 7.07965
603 3DMH GMP 7.07965
604 3DMH SAM 7.07965
605 1GET NAP 7.07965
606 1GET FAD 7.07965
607 3AXB PRO 7.07965
608 3AXB FAD 7.07965
609 2I7C AAT 7.07965
610 2PT9 S4M 7.07965
611 2PT9 2MH 7.07965
612 1QO8 FAD 7.07965
613 4EMI NAD 7.07965
614 4EMI FAD 7.07965
615 4EMJ FAD 7.07965
616 5GSN FAD 7.07965
617 5GSN NAP 7.07965
618 3MAG SAH 7.07965
619 5GSN MMZ 7.07965
620 4K5S FAD 7.07965
621 4K5S PM0 7.07965
622 3MCT SAH 7.07965
623 5G3U FDA 7.07965
624 4PLT OXM 7.07965
625 5YU3 NAD 7.07965
626 5YU3 PRO 7.07965
627 4PLT NAI 7.07965
628 3HB5 NAP 7.07965
629 5G3U ITW 7.07965
630 1XKQ NDP 7.07965
631 1C1X NAD 7.07965
632 4XFR CIT 7.07965
633 1BXG NAD 7.07965
634 3TKY SAH 7.07965
635 1BW9 NAD 7.07965
636 5K7U SAM 7.07965
637 3RIY NAD 7.07965
638 3SJU NDP 7.07965
639 6EQS BV8 7.07965
640 2C5A NAD 7.07965
641 2C5A GDC 7.07965
642 5ZBC FAD 7.07965
643 1O5O U5P 7.23982
644 2CUL FAD 7.32759
645 1X87 NAD 7.52212
646 1FEC FAD 7.52212
647 5BUK FAD 7.52212
648 2IVD FAD 7.52212
649 6FP4 E1T 7.52212
650 6FP4 FAD 7.52212
651 1H5Q NAP 7.52212
652 1Z45 NAD 7.52212
653 5YB7 FAD 7.52212
654 5YB7 ORN 7.52212
655 5O9F NAD 7.52212
656 5O9F 9ON 7.52212
657 5M58 SAH 7.52212
658 1KYQ NAD 7.52212
659 1I7M CG 7.52212
660 4JK3 NAD 7.52212
661 3Q9N COA 7.59494
662 4P86 5GP 7.65027
663 5O42 9JW 7.66423
664 5O42 NAD 7.66423
665 5O42 BGC 7.66423
666 1XDS SAM 7.75401
667 2YG3 FAD 7.94702
668 2RAB NAD 7.9646
669 2RAB FAD 7.9646
670 6F97 FAD 7.9646
671 1PN0 FAD 7.9646
672 2JB2 FAD 7.9646
673 2JB2 PHE 7.9646
674 1PN0 IPH 7.9646
675 5JCA FAD 7.9646
676 2QA1 FAD 7.9646
677 5JCA NDP 7.9646
678 3QFA FAD 7.9646
679 2ZJ1 ARJ 7.9646
680 2ZJ1 NAD 7.9646
681 4ITU 1HS 7.9646
682 4ITU NAI 7.9646
683 6GAS FAD 7.9646
684 1PJS NAD 7.9646
685 1SOW NAD 7.9646
686 1O97 FAD 7.9646
687 5TVF CGQ 7.9646
688 1O97 AMP 7.9646
689 1V5F FAD 7.9646
690 1V5F TPP 7.9646
691 1OBB NAD 7.9646
692 5MGZ SAH 7.9646
693 6F9Q NAD 7.9646
694 1O94 ADP 7.9646
695 4J7U NAP 7.9646
696 4J7U YTZ 7.9646
697 1U72 NDP 8.06452
698 1U72 MTX 8.06452
699 2GAG NAD 8.08081
700 2GAG FAD 8.08081
701 2GAG FOA 8.08081
702 1ZBQ NAD 8.25688
703 2PWY SAH 8.40708
704 3G2O SAM 8.40708
705 6BQ6 TER 8.40708
706 3VSE SAH 8.40708
707 5VN0 NAI 8.40708
708 5VN0 FAD 8.40708
709 1PS9 FAD 8.40708
710 4URF NAD 8.40708
711 1TLG GAL 8.40708
712 1DSS NAD 8.40708
713 5IL1 SAM 8.40708
714 4RQU NAD 8.40708
715 2PZM UDP 8.40708
716 2PZM NAD 8.40708
717 4FC7 COA 8.40708
718 4FC7 NAP 8.40708
719 2PX8 SAH 8.40708
720 3L9W AMP 8.84956
721 3L9W GSH 8.84956
722 1WG8 SAM 8.84956
723 1Q9I FAD 8.84956
724 1Q9I TEO 8.84956
725 3A25 SAM 8.84956
726 3OND ADN 8.84956
727 3OND NAD 8.84956
728 4DSG FAD 8.84956
729 4DSG UDP 8.84956
730 4K26 NDP 8.84956
731 4K26 SFF 8.84956
732 3I53 SAH 8.84956
733 4POO SAM 9
734 2DT5 NAD 9.00474
735 4M37 SAH 9.29204
736 4M38 SAH 9.29204
737 5YF1 8V0 9.29204
738 1GY8 NAD 9.29204
739 5YF1 SFG 9.29204
740 5MBX FAD 9.29204
741 5MBX SP5 9.29204
742 5YJI 8WO 9.29204
743 5YJI SAH 9.29204
744 3ZNN FAD 9.29204
745 3ZNN 4WL 9.29204
746 6BWL NAD 9.29204
747 5XNC MTA 9.29204
748 1DLJ NAI 9.29204
749 1DLJ UGA 9.29204
750 5ZZ6 ADP 9.61539
751 5ZZ6 NAD 9.61539
752 3LAD FAD 9.73451
753 3KLJ FAD 9.73451
754 4D7E FAD 9.73451
755 3QVP FAD 9.73451
756 4XQC 13D 9.73451
757 4XQC NAD 9.73451
758 2EFJ SAH 9.73451
759 1VL8 NAP 9.73451
760 3OJO NAD 9.73451
761 1UXG FUM 9.73451
762 1UXG NAD 9.73451
763 1KYZ SAH 9.73451
764 2D3N GLC GLC GLC 9.73451
765 4OM8 NAD 9.73451
766 6CI9 NAP 9.73451
767 2XYQ SAH 9.83607
768 5G3L SIA 10.101
769 4Y30 49L 10.177
770 4Y30 SAH 10.177
771 2EJU SAH 10.177
772 4EUE NAI 10.177
773 1MO9 FAD 10.177
774 1MO9 KPC 10.177
775 3LZW FAD 10.177
776 2RGO FAD 10.177
777 3U4C NDP 10.177
778 1EDO NAP 10.177
779 4KWI NAP 10.2662
780 4KWI 1TJ 10.2662
781 3VYW SAM 10.6195
782 5DM1 SAH 10.6195
783 5DM1 5D7 10.6195
784 5MPT SAH 10.6195
785 1VQW FAD 10.6195
786 2GV8 FAD 10.6195
787 2GVC FAD 10.6195
788 4C3Y FAD 10.6195
789 2NPX NAD 10.6195
790 2NPX FAD 10.6195
791 4C3Y ANB 10.6195
792 4D04 FAD 10.6195
793 4D04 NAP 10.6195
794 1UDB NAD 10.6195
795 1UDB UFG 10.6195
796 2WSB NAD 10.6195
797 1ORR NAD 10.6195
798 2DC1 NAD 10.6195
799 1KK8 BEF ADP 10.6195
800 1MUU NAD 10.6195
801 1LSS NAD 10.7143
802 1UWK URO 11.0619
803 1UWK NAD 11.0619
804 3GDN HBX 11.0619
805 3GDN FAD 11.0619
806 4BJZ FAD 11.0619
807 4BJZ P3A 11.0619
808 1JNR FAD 11.0619
809 6CEP NAD 11.0619
810 1VE3 SAM 11.0619
811 4YKG FAD 11.0619
812 4YKG NAD 11.0619
813 1FL2 FAD 11.0619
814 1MV8 NAD 11.0619
815 3MB5 SAM 11.5044
816 5WP5 SAH 11.5044
817 5GWX SAR 11.5044
818 5GWX SAM 11.5044
819 3G89 SAM 11.5044
820 4MO2 FDA 11.5044
821 4MO2 FAD 11.5044
822 1UP7 NAD 11.5044
823 1U7T TDT 11.5044
824 5JWC FAD 11.5044
825 2WR9 MAN MAN 11.7188
826 2Y6Q I7T 11.9469
827 2Y6Q FAD 11.9469
828 4U8P UDP 11.9469
829 4U8P FDA 11.9469
830 1GTE FAD 11.9469
831 9LDT NAD 11.9469
832 9LDB NAD 11.9469
833 1CER NAD 11.9469
834 1GEG NAD 12.1094
835 3QV1 NAD 12.1951
836 3AD8 NAD 12.3153
837 3AD8 PYC 12.3153
838 3AD8 FAD 12.3153
839 3A27 SAM 12.3894
840 3S1S SAH 12.3894
841 4N49 SAM 12.3894
842 4ZVV NAD 12.3894
843 4ZVV GN0 12.3894
844 5ODQ FAD 12.3894
845 6F3N NAD 12.3894
846 6F3N ADN 12.3894
847 6F3M NAD 12.3894
848 2WPF WPF 12.8319
849 2WPF FAD 12.8319
850 4CNK FAD 12.8319
851 2HK9 ATR 12.8319
852 1E3W NAD 12.8319
853 1E6W NAD 12.8319
854 1PNO NAP 12.8319
855 2HK9 NAP 12.8319
856 3LXD FAD 13.2743
857 3K7M FAD 13.2743
858 2Q46 NAP 13.2743
859 4II2 ATP 13.4969
860 5E8J SAH 13.6364
861 1XHC FAD 13.7168
862 1BZL GCG 13.7168
863 1BZL FAD 13.7168
864 4YSX FAD 13.7168
865 4TM3 FAD 13.7168
866 4AZW SAM 13.7168
867 1EU1 MGD 13.7168
868 2F5Z FAD 14.0625
869 5THZ SAH 14.1593
870 2B9W FAD 14.1593
871 4OBW SAM 14.1593
872 1GV0 NAD 14.1593
873 1JA9 NDP 14.1593
874 4TXI FAD 14.6018
875 2BRY FAD 14.6018
876 3GEG NAD 14.6018
877 2OOR NAD 14.6018
878 2OOR TXP 14.6018
879 1NM5 NAP 14.6018
880 1NM5 NAD 14.6018
881 1L7E NAI 14.6018
882 5EIN NAP 14.8148
883 4X60 SFG 15.0442
884 4X60 3XV 15.0442
885 4GQB 0XU 15.0442
886 1NAA 6FA 15.0442
887 1NAA ABL 15.0442
888 6AIN FAD 15.0442
889 5FA5 MTA 15.0442
890 3X0V FAD 15.0442
891 1EFV FAD 15.2941
892 1EFV AMP 15.2941
893 5FUB SAH 15.4867
894 1UAY ADN 15.4867
895 4C4A SAH 15.9292
896 1TPY SAH 15.9292
897 3BJE URA 15.9292
898 1L1E SAH 15.9292
899 1F8G NAD 15.9292
900 3ZFD ANP 15.9292
901 2VHW NAI 16.3717
902 1WVG APR 16.3717
903 3A4T SFG 16.8142
904 1V6A TRE 16.8142
905 1HYH NAD 16.8142
906 5Z75 NAD 16.8142
907 1E6E FAD 17.2566
908 5MIT FAD 17.2566
909 5MIT NAP 17.2566
910 5BRT FAD 17.6991
911 5BRT CH9 17.6991
912 5XLX SAH 17.6991
913 1GUZ NAD 18.1416
914 5Z2L NDP 18.7755
915 5ERG SAM 19.0265
916 3IWD M2T 19.1176
917 1ZQ9 SAM 19.469
918 5JJR SAH 19.9115
919 2WET FAD 21.2389
920 2B4Q NAP 22.5664
921 3SSO SAH 23.4513
922 3ABI NAD 23.4513
923 5WP4 SAH 23.8938
924 1DL5 SAH 26.1062
925 3TKA SAM 26.1062
926 1JG3 ADN 27.8761
927 1I1N SAH 27.8761
928 3JWH SAH 28.1106
929 3HVJ 705 29.646
930 4XUC SAM 30.0885
931 4XUC 43G 30.0885
932 3QJ4 FAD 30.9735
933 1R18 SAH 32.7434
934 3R75 PYR 33.6283
935 3C3Y SAH 37.1681
936 5ZW3 SAH 37.6106
937 3CBG SAH 46.0177
Pocket No.: 2; Query (leader) PDB : 5N5D; Ligand: SAM; Similar sites found with APoc: 19
This union binding pocket(no: 2) in the query (biounit: 5n5d.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 3WQQ NDP 1.76991
2 3WQQ IB3 1.76991
3 3CQL NAG 2.65487
4 4GUS FAD 3.22581
5 4FK7 P34 3.53982
6 4TQK NAG 3.53982
7 2JK0 ASP 3.53982
8 1GVF PGH 4.42478
9 1U25 IHS 4.86726
10 4CFT H4B 5.30973
11 4CU1 H4B 5.30973
12 4KOA NDP 6.63717
13 3Q9T FAY 6.63717
14 1VM6 NAD 6.63717
15 2OFD NGA 9.15493
16 5ICE 2H4 9.73451
17 5ICE SAH 9.73451
18 1E1M FAD 12.8319
19 1E1M NAP 12.8319
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