Receptor
PDB id Resolution Class Description Source Keywords
5LXC 2.15 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF DYRK2 IN COMPLEX WITH EHT 5372 (COMPOUN HOMO SAPIENS TRANSFERASE KINASE INHIBITOR UNUSUAL BINDING MODE STRUCTGENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC
Ref.: AN UNUSUAL BINDING MODEL OF THE METHYL 9-ANILINOTHIAZOLO[5,4-F] QUINAZOLINE-2-CARBIMIDATES 1610 AND EHT 5372) CONFERS HIGH SELECTIVITY FOR DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED J. MED. CHEM. V. 59 10315 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:505;
B:504;
A:503;
A:504;
B:502;
A:502;
A:509;
A:507;
B:503;
A:508;
A:506;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
7AA A:501;
B:501;
Valid;
Valid;
none;
none;
ic50 = 10.8 nM
404.273 C17 H11 Cl2 N5 O S COC(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LXC 2.15 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF DYRK2 IN COMPLEX WITH EHT 5372 (COMPOUN HOMO SAPIENS TRANSFERASE KINASE INHIBITOR UNUSUAL BINDING MODE STRUCTGENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC
Ref.: AN UNUSUAL BINDING MODEL OF THE METHYL 9-ANILINOTHIAZOLO[5,4-F] QUINAZOLINE-2-CARBIMIDATES 1610 AND EHT 5372) CONFERS HIGH SELECTIVITY FOR DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED J. MED. CHEM. V. 59 10315 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5LXC ic50 = 10.8 nM 7AA C17 H11 Cl2 N5 O S COC(=N)c1n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 5LXC ic50 = 10.8 nM 7AA C17 H11 Cl2 N5 O S COC(=N)c1n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 5LXC ic50 = 10.8 nM 7AA C17 H11 Cl2 N5 O S COC(=N)c1n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 7AA; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 7AA 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LXC; Ligand: 7AA; Similar sites found: 335
This union binding pocket(no: 1) in the query (biounit: 5lxc.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2XOC ADP 0.014 0.41632 1.53257
2 4UWH JXM 0.000259 0.46937 1.71569
3 2CFM AMP 0.001261 0.44844 1.71569
4 5FCF GLY GLY GLY 0.002602 0.43988 1.75439
5 3TTN SPD 0.01377 0.41013 1.76471
6 5MW8 ATP 0.0000005894 0.51936 1.96078
7 5VZ0 ADP 0.0001084 0.47707 1.96078
8 2VQD AP2 0.000145 0.44977 1.96078
9 5GZ9 ANP 0.000000007537 0.5835 1.96721
10 3CBC DBS 0.007931 0.41927 2.0202
11 5COU ATP 0.001657 0.43545 2.05882
12 3ZJX BOG 0.004865 0.43414 2.07612
13 1CKM GTP 0.0111 0.40798 2.12121
14 2YW2 ATP 0.0007994 0.42134 2.20588
15 3TY5 ATP 0.006838 0.41367 2.20588
16 3TY5 ADP 0.00764 0.40315 2.20588
17 3ORQ ADP 0.001041 0.41741 2.38727
18 2AQX ATP 0.0006162 0.41844 2.42215
19 3PN1 IVH 0.001626 0.4543 2.51572
20 5DMM HCS 0.0169 0.40625 2.58065
21 2VPQ ANP 0.00004631 0.45213 2.69608
22 3HQP OXL 0.006647 0.43249 2.69608
23 4ZGP ADP 0.0007669 0.43995 2.73038
24 4FE2 ADP 0.008011 0.40619 2.7451
25 3TTM PUT 0.009949 0.41339 2.89017
26 4U98 ACP 0.0001806 0.4676 2.94118
27 3BOF HCS 0.008383 0.4203 2.94118
28 1Q8A HCS 0.009601 0.41715 2.94118
29 4PU5 ANP 0.001479 0.40264 2.94118
30 3Q60 ATP 0.000003452 0.54097 2.96496
31 2PUL ACP 0.0000007354 0.56926 3.02267
32 5TT6 ATP 0.0004558 0.42118 3.04569
33 4LH7 1X8 0.0004331 0.48589 3.09598
34 4OCJ NDG 0.000004237 0.41144 3.16623
35 2PYW ADP 0.0000007315 0.53395 3.18627
36 1M0W ANP 0.0004355 0.45921 3.18627
37 2Z48 A2G 0.008122 0.41989 3.18627
38 2Z49 AMG 0.01047 0.41714 3.18627
39 1IA9 ANP 0.000003406 0.51958 3.21429
40 4ZS4 ATP 0.000001587 0.53405 3.25733
41 1I7E IBS 0.02141 0.4009 3.39623
42 4OCV ANP 0.000004398 0.51664 3.43008
43 3K5I ADP 0.0009318 0.41994 3.47395
44 1A99 PUT 0.01409 0.40853 3.48837
45 5W2I I3P 0.00004583 0.44211 3.50195
46 5W2I ADP 0.00004583 0.44211 3.50195
47 2BKK ADP 0.0002182 0.47843 3.5503
48 3X01 AMP 0.00002553 0.54905 3.56234
49 1XDN ATP 0.005775 0.40864 3.61011
50 1TZD ADP 0.00002126 0.55701 3.63636
51 3PDT ADP 0.0000128 0.52816 3.63636
52 3ETH ATP 0.0005529 0.41903 3.66197
53 2IF8 ADP 0.00001376 0.55767 3.67647
54 1W2D ADP 0.00007308 0.50694 3.77358
55 2GQR ADP 0.002565 0.41704 3.79747
56 2GQS ADP 0.005499 0.40443 3.79747
57 1ZTH ADP 0.0000003304 0.61782 3.87597
58 1ZP9 ATP 0.000001007 0.57785 3.87597
59 2YRX AMP 0.0005124 0.48204 3.99113
60 3AKK ADP 0.0001201 0.46084 4
61 3I0O ADP 0.00001037 0.54704 4.12979
62 3V4S ATP 0.001993 0.40175 4.13437
63 3VOT ADP 0.0001267 0.49564 4.16667
64 4XYM A12 0.0006453 0.4298 4.16667
65 2IO8 ADP 0.00002031 0.45416 4.41176
66 5VC5 96M 0.0000001185 0.5094 4.49827
67 1M26 GAL A2G 0.0195 0.40581 4.51128
68 1OGX EQU 0.007882 0.40253 4.58015
69 5KO1 6UY 0.000001356 0.5583 4.59364
70 3HAV ATP 0.0001666 0.5068 4.68227
71 4R78 AMP 0.00001315 0.55014 5.17799
72 1EHI ADP 0.000474 0.43549 5.30504
73 3VPC ADP 0.00001776 0.4751 5.31915
74 4B1L FRU 0.005196 0.43595 5.45455
75 4OAV ACP 0.00000004923 0.62079 5.63725
76 5C1P ADP 0.0001418 0.48706 5.88235
77 5C1P DAL DAL 0.0003731 0.40705 5.88235
78 4GLW 0XT 0.002168 0.44251 5.90164
79 4PZ6 GMP 0.001176 0.46504 6.20347
80 3BP1 GUN 0.004766 0.43676 6.2069
81 4AZT LY2 0.0002753 0.4797 6.37255
82 5TDF ADP 0.001291 0.41299 6.37255
83 3FIU AMP 0.007257 0.41244 6.4257
84 4OUC 5ID 0.000000004012 0.68586 6.44258
85 4O4F ATP 0.0006 0.40422 6.45161
86 3UDZ ADP 0.0000006892 0.54529 6.61765
87 1OBD ATP 0.007655 0.4071 6.86275
88 3PNA CMP 0.008959 0.41252 7.14286
89 5EXK 5AD 0.005327 0.42855 7.25076
90 1HFE CYS 0.0203 0.40446 7.31707
91 1VKF CIT 0.01759 0.40351 7.44681
92 1S68 AMP 0.003316 0.43884 7.63052
93 4GYI ADP 0.000008009 0.54462 7.80856
94 1TQP ATP 0.000003718 0.48208 8.15603
95 5IQD GNP 0.00001378 0.40951 8.19672
96 5IQD RIO 0.00001487 0.40412 8.19672
97 3RE4 TO1 0.0000004767 0.61029 8.52713
98 4CYI ATP 0.000006348 0.49668 8.82353
99 3W0O HY0 0.00004346 0.41516 9.74212
100 3W0O ADP 0.00004346 0.41516 9.74212
101 4O1P ANP 0.000000006652 0.64058 9.80392
102 1PVC ILE SER GLU VAL 0.005475 0.4541 9.96678
103 2CDO GAL AAL GAL AAL GAL AAL 0.01524 0.41389 10
104 5I35 ANP 0.0000001287 0.60239 10.1781
105 1CBK ROI 0.005607 0.42865 10.625
106 3VPB ADP 0.000002312 0.4809 10.7143
107 5C03 AGS 0.000006856 0.51757 11.1111
108 5C8W PCG 0.003084 0.43506 11.8881
109 4WOV 3SM 0.00001525 0.53171 11.9874
110 4Q5H ANP 0.000002853 0.53512 12.069
111 1G1T SIA GAL MAG FUC 0.01581 0.40904 12.1019
112 4LRJ ANP 0.0000006144 0.57438 12.426
113 3UIM ANP 0.00000003946 0.60981 12.5767
114 5M06 ADP 0.0000007045 0.58484 13.7681
115 3VHE 42Q 0.00000001093 0.51139 13.9276
116 3LXK MI1 0.00000004652 0.51918 14.0673
117 4YMJ 4EJ 0.000000007363 0.73074 14.1447
118 3LXN MI1 0.0000000007297 0.64456 14.1509
119 3C1X CKK 0.00001674 0.47054 14.2091
120 3WH2 FLC 0.0143 0.41923 14.966
121 4AT3 LTI 0.0000007796 0.46504 15.0502
122 4GJ3 0XP 0.00000000171 0.529 15.2318
123 4E1Z 0MX 0.00000005317 0.55395 15.4639
124 4YZC STU 0.000000001212 0.49599 15.8025
125 4G31 0WH 0.0000002272 0.4509 16.388
126 2QK4 ATP 0.00009853 0.50768 16.4216
127 1JBU BEN 0.004324 0.40079 16.5354
128 2X2M X2M 0.0000000007447 0.62837 16.5605
129 3KMW ATP 0.0000348 0.49815 18.8192
130 2QX0 PH2 0.003915 0.43826 18.8679
131 4I94 ANP 0.00000008175 0.60967 19.3333
132 5USZ SKE 0.0000003746 0.49256 20.0692
133 1U59 STU 0.0000000004918 0.68657 20.3431
134 4FL3 ANP 0.00000001526 0.58813 20.5882
135 2H8H H8H 0.00000009167 0.59475 21.0784
136 4G17 0VN 0.0000001404 0.61636 21.2121
137 3VRY B43 0.0000002454 0.51127 22.0588
138 4E93 GUI 0.000000006112 0.51078 23.0769
139 4L9I 8PR 0.0000001609 0.59981 23.2843
140 4WNK 453 0.000000007402 0.53055 23.5294
141 1OPK P16 0.0000002384 0.46694 24.0196
142 3PVW QRX 0.000000005612 0.55552 24.2647
143 5UKL SIX 0.0000001956 0.50584 24.2647
144 2RIO ADP 0.000000004165 0.66654 24.5098
145 1VJY 460 0.000000003827 0.5121 24.7525
146 4Y93 746 0.0000006608 0.49823 24.7549
147 5DMZ ADP 0.000000001846 0.66448 25.2055
148 2PZI AXX 0.000003631 0.56046 25.2451
149 4BKJ STI 0.00002673 0.44081 25.3968
150 4Y0X ADP 0.0000006016 0.58792 25.6
151 3KRL KRL 0.0000003201 0.53419 25.6716
152 1Y57 MPZ 0.000001029 0.5085 25.7353
153 4WB7 ATP 0.000000001527 0.49547 26.1728
154 2R5T ANP 0.00000000134 0.61953 26.2735
155 5T8O 76Z 0.00000002137 0.58941 26.361
156 4OH4 ANP 0.00000002053 0.62116 26.4264
157 5NKB 8ZT 0.000000171 0.42708 26.4706
158 5TA6 79D 0.0000003985 0.49467 26.5363
159 5W4W 9WG 0.000000009626 0.5072 26.5861
160 4KBA 1QM 0.0000001406 0.50006 26.5861
161 4IDT T28 0.000000008082 0.65436 26.6854
162 3PP0 03Q 0.00000006223 0.52001 27.2189
163 4N70 2HX 0.000000009569 0.42323 27.439
164 3V8S 0HD 0.000000001872 0.67986 27.451
165 3H9R TAK 0.000001732 0.59286 27.5758
166 1U5R ATP 0.000000001392 0.66645 27.5862
167 1K3A ACP 0.0000001316 0.6269 27.7592
168 5MJA 7O3 0.0000003515 0.59843 27.8689
169 5U6C 7YS 0.0000002969 0.54074 27.9365
170 4FF8 14S 0.006198 0.41569 28.1734
171 4DC2 ADE 0.000000003516 0.75512 28.2828
172 1RDL MMA 0.02151 0.4103 28.3186
173 2XVD AS6 0.00000031 0.48865 28.4768
174 1JPA ANP 0.0000009928 0.61384 28.5256
175 2JDR L20 0.00000000434 0.40116 28.655
176 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.00000000434 0.40116 28.655
177 4P5Z Q7M 0.0000007192 0.42968 28.8089
178 4X7Q 3YR 0.0000000007269 0.67849 28.8462
179 5JFS 6K0 0.00000001638 0.45204 28.8961
180 3SXF BK5 0.000000003025 0.50373 28.9216
181 1XJD STU 0.0000000001102 0.69254 28.9855
182 4U44 3D9 0.0000001666 0.58375 29.2169
183 5HCY 60D 0.0000001737 0.42327 29.3051
184 4BFM ANP 0.00000000008019 0.6826 29.3413
185 4BTK DTQ 0.0000004407 0.56791 29.3769
186 3DLS ADP 0.000000002912 0.69212 29.5522
187 5IH9 6BF 0.0000001082 0.45723 29.5522
188 2Y6O 1N1 0.0000003584 0.53152 29.5533
189 4OTH DRN 0.0000000005737 0.63535 29.6188
190 3BU5 ATP 0.000000002978 0.65401 29.7386
191 5HVJ ANP 0.000000001967 0.76636 29.8413
192 3MVH WFE 0.0000000004469 0.55129 30.117
193 2F57 23D 0.000000164 0.61333 30.2839
194 2OO8 RAJ 0.0001978 0.43245 30.2839
195 2QCS ANP 0.00000000007661 0.60829 30.2857
196 5CEO 50D 0.0000008783 0.55287 30.3333
197 5N87 N66 0.00000001492 0.47877 30.3514
198 2PVF ACP 0.000000004854 0.66277 30.5389
199 3IDB ANP 0.0000000003945 0.62155 30.5714
200 3FHI ANP 0.0000000001265 0.60271 30.5714
201 1RE8 BD2 0.00000000103 0.44579 30.5714
202 3EKK GS2 0.00000002095 0.47201 30.6189
203 4YZN 4K5 0.00000000007182 0.65021 30.662
204 3GQI ACP 0.00000001367 0.62629 30.6748
205 4WB6 ATP 0.0000000001044 0.60498 30.8571
206 3PLS ANP 0.00000001828 0.63831 30.8725
207 4CLI 5P8 0.0000002295 0.41932 30.8869
208 3NW7 LGV 0.0000008901 0.40027 30.9446
209 2WQN ADP 0.00000005963 0.64275 30.9677
210 3KN5 ANP 0.00000001928 0.66536 31.0769
211 4I6H 1C8 0.000001894 0.53992 31.1688
212 5VCV 1N1 0.000000000405 0.60956 31.1897
213 2YAB AMP 0.000000003259 0.63806 31.5789
214 4EWH T77 0.000000005996 0.54413 31.6364
215 5LI1 ANP 0.00000000002542 0.68251 31.6384
216 4K33 ACP 0.00000000836 0.62053 31.6923
217 5JGA 6KC 0.00000000416 0.51203 31.746
218 2GU8 796 0.000000001184 0.41301 31.7507
219 4Y8D 49J 0.000000005293 0.64417 31.7647
220 2OFV 242 0.0000009083 0.43552 31.769
221 5LI9 ACP 0.000000002515 0.64104 32
222 4U0I 0LI 0.000001479 0.44172 32.0635
223 3HMO STU 0.000000007272 0.65629 32.1637
224 4QMN DB8 0.0000001064 0.45905 32.2581
225 4C2V YJA 0.00000005219 0.50393 32.2807
226 5AX9 4KT 0.0000001191 0.58938 32.4675
227 3RI1 3RH 0.000000064 0.52444 32.5879
228 1ZY5 ANP 0.000002958 0.54386 32.6733
229 5DH3 5BS 0.00000009097 0.56654 32.6984
230 5JKG 6LF 0.0000002965 0.43658 32.7974
231 5UR1 YY9 0.0000002744 0.42632 32.7974
232 5FBN 5WF 0.000001791 0.43823 32.8413
233 3SRV S19 0.0000000000781 0.73963 32.852
234 4C2W ANP 0.000000002864 0.71533 32.9749
235 4XLI 1N1 0.0000002863 0.58687 33.209
236 4M69 ANP 0.0000003147 0.55075 33.2155
237 4KS7 X4Z 0.00000004765 0.55797 33.2192
238 4AG8 AXI 0.00000002525 0.46715 33.2278
239 4NFN 2KC 0.00000297 0.54374 33.3333
240 2HK5 1BM 0.0000004849 0.53906 33.3333
241 4Y85 499 0.00003349 0.50013 33.4337
242 3TKI S25 0.000000002235 0.42131 33.4365
243 2HY0 306 0.00000009291 0.63387 33.5404
244 3SLS ANP 0.00000004256 0.56529 33.5526
245 1PHK ATP 0.00000000004034 0.70764 33.557
246 3SXS PP2 0.00000002472 0.58703 33.5821
247 5TO8 7FM 0.0000002379 0.43325 33.6879
248 5EYK 5U5 0.00000003115 0.52278 33.6957
249 4WNP 3RJ 0.000000001291 0.71951 33.7979
250 4D2S DYK 0.00000005874 0.64305 33.8028
251 3HZT J60 0.000000004408 0.70647 33.8235
252 4TWP AXI 0.00000008327 0.4159 33.9483
253 3TXO 07U 0.00000000006878 0.76534 33.9943
254 4JDI ANP 0.0000000008353 0.64337 34.104
255 2X4Z X4Z 0.0000003014 0.46022 34.1216
256 1BYG STU 0.000000003791 0.68697 34.1727
257 4NST ADP 0.000000002149 0.66095 34.188
258 4XV1 904 0.00000003392 0.47779 34.2466
259 5UIU 8CG 0.00000001229 0.51745 34.3653
260 5LVP ATP 0.000000009773 0.67897 34.4051
261 3ALN ANP 0.00000006793 0.57246 34.5566
262 2QLU ADE 0.000001837 0.60904 34.7134
263 4BHN BH9 0.000000001993 0.63007 34.7305
264 5L8L ADP 0.00000001767 0.67796 34.7368
265 5G1X ADP 0.000000004704 0.66476 34.7368
266 5H2U 1N1 0.0000009263 0.55232 34.8315
267 5LXM ADP 0.000000001412 0.68638 34.9823
268 3ORK AGS 0.00000007139 0.5326 35.0482
269 5DA3 58V 0.00000003665 0.66298 35.0943
270 4L3L 5FI 0.000000004294 0.52561 35.1974
271 2A19 ANP 0.0000003836 0.61475 35.2113
272 4NW6 2NS 0.0000000004073 0.53635 35.2941
273 4EUU BX7 0.00000006251 0.52237 35.4232
274 5EFQ ADP 0.000000001297 0.66982 35.4467
275 3GNI ATP 0.00000007847 0.56801 35.4756
276 3DAK ANP 0.00000005784 0.6337 35.5172
277 4ASE AV9 0.0000001331 0.49398 35.694
278 5HX8 66P 0.000000007771 0.54876 35.7616
279 2ZV2 609 0.0000000001475 0.77624 35.906
280 4CQE CQE 0.0000002896 0.53302 35.9712
281 2Z7R STU 0.00000000002946 0.67684 36.4486
282 5HES 032 0.0000000749 0.55607 36.4821
283 4FG8 ATP 0.0000000249 0.59268 36.5079
284 4A4X JUP 0.0000001882 0.50858 36.9176
285 3E5A VX6 0.0000003209 0.51095 36.9403
286 4CSV STI 0.000005284 0.48015 37.0909
287 3IGO ANP 0.0000000005924 0.63321 37.7451
288 4CRL C1I 0.00000005177 0.4788 38.4236
289 3TTI KBI 0.00000002846 0.52847 38.4804
290 2JLD AG1 0.00000004504 0.48907 38.7255
291 5AWM ANP 0.00000001605 0.67993 39.0863
292 3AQV TAK 0.00001845 0.49996 39.4928
293 4JR7 GNP 0.000000000287 0.69472 39.8396
294 3FHR P4O 0.0000001139 0.57574 39.881
295 3E8N VRA 0.0000000535 0.42911 39.8827
296 3E8N ATP 0.0000000535 0.42911 39.8827
297 5JZJ AN2 0.00000000106 0.69172 40.0673
298 5A6N U7E 0.000000005164 0.63026 40.2827
299 5UOX 8GY 0.000000001939 0.6164 40.9594
300 3C0G 3AM 0.000000002606 0.70544 41.0256
301 3GGF GVD 0.0000000115 0.66527 41.196
302 5EKO N17 0.00000574 0.4785 41.5094
303 4NM5 ADP 0.00000002034 0.56855 41.9098
304 4F9C 0SX 0.000000006687 0.65753 42.1053
305 4IZY 1J2 0.000000005558 0.61065 42.5474
306 4UX9 ANP 0.0000000004565 0.65356 42.8571
307 3ZRM ZRM 0.000000007575 0.63962 42.8571
308 2PVN P63 0.0000000002826 0.57015 42.8977
309 3PTG 932 0.00000001966 0.68726 43.2507
310 2V7O DRN 0.00000000007691 0.80411 43.4524
311 4QTB 38Z 0.0000000005484 0.56793 43.6842
312 2WEL K88 0.00000002001 0.70754 43.7309
313 4USF 6UI 0.00005111 0.44371 43.75
314 1CM8 ANP 0.0000002778 0.5882 44.1417
315 4H3P ANP 0.000000007677 0.63783 44.7514
316 4LOO SB4 0.000001007 0.55197 45.1524
317 2B9J ADP 0.0000000007405 0.69902 45.3258
318 2B9I ADP 0.0000000006814 0.6821 45.3258
319 2B9F ADP 0.0000000008386 0.67802 45.3258
320 2B9H ADP 0.0000000008035 0.66188 45.3258
321 3F7Z 34O 0.00000001279 0.63127 45.4286
322 3M2W L8I 0.0000000001703 0.76008 45.485
323 3E7O 35F 0.00000005766 0.47388 45.5556
324 3GC0 AMP 0.000001043 0.58544 45.5927
325 5BYZ 4WE 0.000001608 0.45181 46.2644
326 2VZ6 FEF 0.000000008669 0.68137 46.3259
327 3OFM 4B0 0.0000000006919 0.732 46.5714
328 4H3Q ANP 0.000000001059 0.6122 46.6851
329 5MY8 RXZ 0.000000002501 0.57405 46.7363
330 3GC8 B45 0.0000004804 0.52843 46.7568
331 3PE2 E1B 0.00000002855 0.42559 46.8843
332 1Q8Y ADE 0.000000002514 0.73061 46.9169
333 1Q8Y ADP 0.00000000009903 0.67971 46.9169
334 2YAK OSV 0.000000001958 0.5376 47.3684
335 2VN9 GVD 0.00000000001827 0.83441 47.5083
336 3CY2 MB9 0.0000000006381 0.61766 50
Pocket No.: 2; Query (leader) PDB : 5LXC; Ligand: 7AA; Similar sites found: 13
This union binding pocket(no: 2) in the query (biounit: 5lxc.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4YZ5 SLT 0.03038 0.40205 2.21566
2 5E1Q LAT GLA 0.02018 0.40157 2.45098
3 3MI3 LYS 0.01456 0.40874 2.69608
4 5FS0 5JC 0.01616 0.40206 2.8436
5 3KDM TES 0.02022 0.40187 3.11111
6 1YFS ALA 0.02173 0.40276 3.67647
7 4KU7 PCG 0.009793 0.40427 3.92157
8 4O4F IHP 0.0001979 0.41943 6.45161
9 3VSV XYS 0.01841 0.40469 6.61765
10 4N14 WR7 0.01216 0.41478 7.64331
11 3G5D 1N1 0.0000001197 0.40565 29.7203
12 4WHZ 3NL 0.0000005132 0.40519 40.7792
13 5BVE 4VG 0.000000003614 0.4017 46.8144
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