Receptor
PDB id Resolution Class Description Source Keywords
5LPB 1.98 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE BRI1 KINASE DOMAIN (865-1160) IN CO ADP FROM ARABIDOPSIS THALIANA ARABIDOPSIS THALIANA BRASSINOSTEROID RECEPTOR KINASE DOMAIN DUAL-SPECIFICIFY KIMEMBRANE RECEPTOR KINASE PLASMA MEMBRANE TRANSFERASE
Ref.: CRYSTAL STRUCTURES OF THE PHOSPHORYLATED BRI1 KINAS AND IMPLICATIONS FOR BRASSINOSTEROID SIGNAL INITIAT PLANT J. V. 78 31 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:1201;
Valid;
Atoms found LESS than expected: % Diff = 0.259;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5LPB 1.98 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE BRI1 KINASE DOMAIN (865-1160) IN CO ADP FROM ARABIDOPSIS THALIANA ARABIDOPSIS THALIANA BRASSINOSTEROID RECEPTOR KINASE DOMAIN DUAL-SPECIFICIFY KIMEMBRANE RECEPTOR KINASE PLASMA MEMBRANE TRANSFERASE
Ref.: CRYSTAL STRUCTURES OF THE PHOSPHORYLATED BRI1 KINAS AND IMPLICATIONS FOR BRASSINOSTEROID SIGNAL INITIAT PLANT J. V. 78 31 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5LPB - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 5LPZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 5LPB - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 5T1T ic50 = 58 nM 76P C16 H20 N4 O3 CN(C)C1CCC....
2 5T1S ic50 = 84 nM 76Q C27 H29 N3 O Cc1cc(cc(c....
3 2NRU - T12 C22 H24 N4 O6 CC(C)(C)C(....
4 4YO6 - 4GD C17 H14 N6 O Cc1cc(n(n1....
5 2OID - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
6 4ZTN ic50 = 19 nM 4S3 C20 H24 N6 O2 S c1ccc2c(c1....
7 2NRY - STU C28 H26 N4 O3 C[C@@]12[C....
8 4ZTL ic50 = 1.2 uM 4S1 C20 H25 N5 O3 S CCCNc1ncc(....
9 4Y73 ic50 = 0.3 nM XPY C18 H21 F3 N8 O Cn1cc(c(n1....
10 2OIC ic50 = 4 nM STU C28 H26 N4 O3 C[C@@]12[C....
11 5UIS ic50 = 146 nM 8C1 C18 H23 N3 O3 CC(C)Oc1cc....
12 5UIT ic50 = 4.6 nM 8CD C18 H21 N3 O4 CC(C)Oc1cc....
13 5UIU ic50 = 0.2 nM 8CG C18 H20 F N3 O4 CC[C@H]1[C....
14 3UIM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
15 5LPZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
16 5LPB - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 435
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 ATP 0.9 1
3 A2D 0.895522 0.971831
4 AQP 0.887324 1
5 5FA 0.887324 1
6 AP5 0.884058 0.971831
7 B4P 0.884058 0.971831
8 BA3 0.869565 0.971831
9 AN2 0.84507 0.985915
10 M33 0.833333 0.958333
11 ACQ 0.826667 0.972222
12 A 0.823529 0.971429
13 AMP 0.823529 0.971429
14 ACP 0.821918 0.972222
15 AR6 0.810811 0.971831
16 APR 0.810811 0.971831
17 ANP 0.802632 0.972222
18 AD9 0.8 0.972222
19 AGS 0.8 0.945946
20 SAP 0.8 0.945946
21 ADX 0.783784 0.873418
22 CA0 0.783784 0.945205
23 TAT 0.779221 0.958904
24 AMP MG 0.774648 0.891892
25 50T 0.773333 0.958333
26 ABM 0.763889 0.917808
27 APC 0.763158 0.958904
28 PRX 0.763158 0.893333
29 ATF 0.759494 0.958904
30 A22 0.753086 0.985915
31 A12 0.743243 0.958904
32 AP2 0.743243 0.958904
33 ADP MG 0.736842 0.905405
34 SRA 0.736111 0.918919
35 ADQ 0.73494 0.945205
36 25L 0.732558 0.985915
37 ADP BEF 0.727273 0.881579
38 BEF ADP 0.727273 0.881579
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 ADP PO3 0.708861 0.943662
44 PAP 0.708861 0.985714
45 ATR 0.708861 0.971429
46 SRP 0.707317 0.906667
47 7D3 0.706667 0.905405
48 25A 0.702381 0.971831
49 ATP MG 0.7 0.905405
50 OAD 0.697674 0.945205
51 RBY 0.6875 0.932432
52 ADV 0.6875 0.932432
53 00A 0.686047 0.883117
54 5SV 0.682353 0.848101
55 8QN 0.682353 0.931507
56 OOB 0.682353 0.931507
57 3OD 0.681818 0.945205
58 BIS 0.681818 0.933333
59 ADP ALF 0.674699 0.87013
60 ALF ADP 0.674699 0.87013
61 AMO 0.674419 0.932432
62 4AD 0.674419 0.92
63 PAJ 0.674419 0.884615
64 GAP 0.670732 0.893333
65 MAP 0.670588 0.945946
66 DLL 0.666667 0.931507
67 ANP MG 0.666667 0.894737
68 VO4 ADP 0.666667 0.931507
69 AHX 0.666667 0.896104
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LAD 0.651685 0.860759
75 WAQ 0.651685 0.883117
76 PR8 0.651685 0.85
77 ITT 0.65 0.943662
78 7D4 0.65 0.905405
79 G5P 0.648936 0.921053
80 RAB 0.647059 0.84507
81 ADN 0.647059 0.84507
82 XYA 0.647059 0.84507
83 TXA 0.644444 0.932432
84 1ZZ 0.644444 0.839506
85 ME8 0.644444 0.839506
86 NB8 0.644444 0.896104
87 FYA 0.644444 0.905405
88 6AD 0.642857 0.909091
89 ADP BMA 0.640449 0.918919
90 G3A 0.638298 0.921053
91 DAL AMP 0.632184 0.905405
92 AFH 0.631579 0.884615
93 9SN 0.630435 0.871795
94 GTA 0.625 0.886076
95 YAP 0.623656 0.894737
96 FA5 0.623656 0.906667
97 UP5 0.622449 0.92
98 XAH 0.617021 0.839506
99 AV2 0.616279 0.917808
100 AOC 0.615385 0.821918
101 48N 0.612245 0.896104
102 4UV 0.610526 0.894737
103 TXD 0.606061 0.907895
104 DND 0.606061 0.932432
105 NAX 0.606061 0.873418
106 NXX 0.606061 0.932432
107 NAI 0.606061 0.907895
108 6V0 0.606061 0.896104
109 5N5 0.605634 0.819444
110 5AS 0.604938 0.77907
111 A4P 0.60396 0.843373
112 DAT 0.60241 0.905405
113 A2R 0.602273 0.985915
114 TXE 0.6 0.907895
115 OMR 0.6 0.851852
116 4UU 0.597938 0.894737
117 A A 0.597826 0.944444
118 A4D 0.597222 0.819444
119 5CD 0.597222 0.805556
120 AP0 0.594059 0.896104
121 4TC 0.594059 0.896104
122 A3P 0.592593 0.971429
123 139 0.592233 0.873418
124 T5A 0.592233 0.841463
125 7D5 0.592105 0.878378
126 ATP A A A 0.589474 0.930556
127 LAQ 0.585859 0.839506
128 MYR AMP 0.585106 0.817073
129 YLP 0.58 0.819277
130 UPA 0.578431 0.907895
131 7DD 0.578313 0.985714
132 ADJ 0.576923 0.851852
133 3AM 0.576923 0.929577
134 COD 0.575472 0.811765
135 NAD 0.575472 0.931507
136 3AT 0.574713 0.971831
137 JB6 0.574468 0.883117
138 4UW 0.574257 0.860759
139 EP4 0.573333 0.753247
140 A2P 0.573171 0.957143
141 CNA 0.571429 0.932432
142 TYM 0.568627 0.906667
143 PPS 0.568182 0.873418
144 TYR AMP 0.56701 0.881579
145 DTA 0.565789 0.786667
146 M2T 0.565789 0.734177
147 AR6 AR6 0.565657 0.917808
148 A3D 0.564815 0.918919
149 3DH 0.564103 0.773333
150 G5A 0.563218 0.77907
151 YLB 0.563107 0.819277
152 YLC 0.563107 0.839506
153 AMP DBH 0.561224 0.893333
154 MTA 0.558442 0.773333
155 DTP 0.556818 0.905405
156 AHZ 0.554455 0.817073
157 NA7 0.553191 0.958904
158 IOT 0.552381 0.831325
159 7MD 0.55 0.8625
160 ZAS 0.55 0.766234
161 IMO 0.548781 0.929577
162 YLA 0.54717 0.819277
163 NAE 0.544643 0.894737
164 TAD 0.544554 0.884615
165 A5A 0.544444 0.807229
166 2AM 0.544304 0.943662
167 TSB 0.543478 0.819277
168 6RE 0.54321 0.759494
169 AYB 0.542056 0.809524
170 NAQ 0.539823 0.871795
171 V3L 0.539326 0.971831
172 ARG AMP 0.539216 0.829268
173 AF3 ADP 3PG 0.538462 0.8375
174 SSA 0.538462 0.8
175 LA8 ALF 3PG 0.538462 0.8375
176 ALF ADP 3PG 0.538462 0.8375
177 ZID 0.535088 0.918919
178 LPA AMP 0.533981 0.817073
179 54H 0.532609 0.788235
180 52H 0.532609 0.77907
181 VMS 0.532609 0.788235
182 BTX 0.53211 0.841463
183 J7C 0.53012 0.769231
184 A3N 0.53012 0.786667
185 5X8 0.528736 0.763158
186 BT5 0.527273 0.831325
187 5CA 0.526882 0.8
188 53H 0.526882 0.77907
189 ARU 0.526316 0.860759
190 EAD 0.525862 0.873418
191 RGT 0.525253 0.958904
192 OVE 0.52439 0.905405
193 S4M 0.52381 0.666667
194 7DT 0.522727 0.985714
195 GDP 0.522222 0.92
196 DDS 0.522222 0.878378
197 AVV 0.521277 0.896104
198 NDE 0.521008 0.932432
199 7MC 0.518868 0.841463
200 DSH 0.518072 0.725
201 MAO 0.517647 0.759036
202 LSS 0.515789 0.761364
203 DSZ 0.515789 0.8
204 NSS 0.515789 0.8
205 P5A 0.515464 0.744444
206 DZD 0.513514 0.884615
207 NVA LMS 0.510417 0.761364
208 12D 0.509615 0.785714
209 NAD IBO 0.509091 0.87013
210 M24 0.508772 0.85
211 YLY 0.508772 0.809524
212 P1H 0.508333 0.851852
213 5AD 0.506849 0.746479
214 GJV 0.505882 0.75
215 LEU LMS 0.505155 0.761364
216 G A A A 0.504505 0.871795
217 4TA 0.504505 0.807229
218 NAJ PZO 0.504425 0.848101
219 KAA 0.5 0.752809
220 NDC 0.5 0.871795
221 7D7 0.5 0.743243
222 71V 0.5 0.907895
223 A3G 0.5 0.8
224 128 0.5 0.776471
225 GSU 0.5 0.77907
226 N0B 0.495726 0.819277
227 NJP 0.495495 0.945946
228 ODP 0.495495 0.909091
229 2SA 0.494624 0.932432
230 6C6 0.494505 0.881579
231 SFG 0.494382 0.75
232 0WD 0.491071 0.921053
233 YSA 0.490196 0.77907
234 PO4 PO4 A A A A PO4 0.489796 0.902778
235 6IA 0.48913 0.8375
236 SAM 0.48913 0.690476
237 A7D 0.488636 0.776316
238 6FA 0.488 0.841463
239 FB0 0.487805 0.804598
240 NAJ PYZ 0.487179 0.85
241 IDP 0.483516 0.918919
242 A5D 0.483516 0.786667
243 SA8 0.483516 0.707317
244 MHZ 0.483146 0.697674
245 PGS 0.483146 0.883117
246 D5M 0.482353 0.878378
247 DA 0.482353 0.878378
248 NEC 0.482353 0.746667
249 NIA 0.481928 0.822785
250 Y3J 0.480519 0.726027
251 FAD 0.480315 0.851852
252 FAS 0.480315 0.851852
253 FDA 0.48 0.833333
254 N6P 0.479592 0.915493
255 GGZ 0.479167 0.825
256 SAH 0.478261 0.74359
257 SAI 0.478261 0.734177
258 NPW 0.477477 0.886076
259 NDP 0.477477 0.921053
260 AAM 0.476744 0.971429
261 AMZ 0.47561 0.916667
262 C2R 0.47561 0.90411
263 A A A 0.474747 0.905405
264 GTP 0.473684 0.92
265 U A G G 0.473684 0.883117
266 SMM 0.473684 0.686047
267 TXP 0.473214 0.921053
268 NZQ 0.473214 0.909091
269 A3S 0.47191 0.810811
270 AMP NAD 0.470588 0.881579
271 SFD 0.46875 0.734043
272 AIR 0.468354 0.901408
273 AAT 0.468085 0.707317
274 EEM 0.468085 0.690476
275 Z5A 0.466667 0.77907
276 7C5 0.466667 0.818182
277 J7V 0.466667 0.833333
278 62F 0.465649 0.8625
279 FAY 0.462121 0.8625
280 ETB 0.461538 0.833333
281 DCA 0.461538 0.823529
282 A3T 0.461538 0.821918
283 A6D 0.46 0.722892
284 A U 0.459459 0.87013
285 6K6 0.459184 0.930556
286 GEK 0.459184 0.7375
287 RFL 0.458647 0.821429
288 S7M 0.458333 0.690476
289 NAP 0.458333 0.945205
290 4YB 0.457944 0.761364
291 WSA 0.454545 0.788235
292 TAP 0.454545 0.907895
293 FNK 0.454545 0.804598
294 COA 0.453782 0.823529
295 0T1 0.453782 0.823529
296 101 0.453488 0.878378
297 XNP 0.452174 0.873418
298 NA0 0.45082 0.932432
299 7RP 0.448276 0.928571
300 GP3 0.446809 0.921053
301 TM1 0.446602 0.77381
302 APU 0.446429 0.894737
303 PUA 0.445378 0.884615
304 V1N 0.443396 0.917808
305 7RA 0.443182 0.957747
306 30N 0.442623 0.752688
307 CAO 0.442623 0.795455
308 AMX 0.442623 0.833333
309 COS 0.442623 0.804598
310 ACK 0.44186 0.861111
311 QQY 0.44186 0.815789
312 649 0.441441 0.744444
313 0UM 0.44 0.698795
314 NHD 0.439655 0.905405
315 CMX 0.439024 0.823529
316 SCO 0.439024 0.823529
317 GCP 0.438776 0.896104
318 8BR 0.438202 0.906667
319 GNH 0.4375 0.907895
320 3AD 0.4375 0.805556
321 62X 0.435644 0.666667
322 ACO 0.435484 0.795455
323 FCX 0.435484 0.795455
324 FAM 0.435484 0.804598
325 GNP 0.434343 0.896104
326 NMX 0.433071 0.76087
327 MGP 0.43299 0.884615
328 PLP AAD 0.432203 0.741573
329 26A 0.432099 0.763158
330 HAX 0.432 0.804598
331 K15 0.431373 0.682353
332 DG1 0.430894 0.921053
333 1DG 0.430894 0.921053
334 QQX 0.430233 0.805195
335 2VA 0.430108 0.8
336 S8M 0.43 0.759494
337 2MC 0.429688 0.769231
338 3KK 0.428571 0.804598
339 6G0 0.428571 0.884615
340 FYN 0.428571 0.823529
341 P5F 0.428571 0.823529
342 NAD BBN 0.428571 0.841463
343 U G A 0.427481 0.839506
344 AS 0.426966 0.833333
345 FAI 0.426966 0.916667
346 RMB 0.426966 0.873239
347 1RB 0.425287 0.885714
348 MCD 0.425197 0.804598
349 OXK 0.425197 0.804598
350 COK 0.425197 0.804598
351 CA6 0.425197 0.729167
352 SOP 0.425197 0.804598
353 G1R 0.424242 0.907895
354 CC5 0.423077 0.816901
355 SXZ 0.423077 0.710843
356 F2N 0.422535 0.813953
357 NAD CJ3 0.422222 0.811765
358 ANZ 0.422018 0.8
359 CMC 0.421875 0.804598
360 CO6 0.421875 0.804598
361 1VU 0.421875 0.795455
362 ZDA 0.421053 0.864865
363 GDD 0.420561 0.884615
364 GKE 0.420561 0.884615
365 GDC 0.420561 0.884615
366 NFD 0.420168 0.883117
367 GSP 0.42 0.873418
368 D3Y 0.42 0.789474
369 MC4 0.419847 0.76087
370 3L1 0.419753 0.773333
371 3D1 0.419753 0.773333
372 FA9 0.41958 0.864198
373 5GP 0.419355 0.906667
374 G 0.419355 0.906667
375 KB1 0.419048 0.698795
376 SCD 0.418605 0.823529
377 CAJ 0.418605 0.804598
378 2BA 0.417582 0.915493
379 CMP 0.417582 0.901408
380 SO8 0.416667 0.789474
381 N01 0.416667 0.905405
382 VRT 0.416667 0.769231
383 3HC 0.415385 0.813953
384 A1S 0.415385 0.804598
385 BCO 0.415385 0.804598
386 IVC 0.415385 0.813953
387 MLC 0.415385 0.804598
388 1HE 0.415385 0.786517
389 NMN AMP PO4 0.415254 0.87013
390 2FA 0.414634 0.813333
391 MGO 0.414141 0.860759
392 3NZ 0.413462 0.782051
393 MCA 0.412214 0.795455
394 CAA 0.412214 0.813953
395 YE1 0.412214 0.813953
396 COO 0.412214 0.804598
397 GAV 0.411765 0.884615
398 P2P 0.411111 0.902778
399 JLN 0.411111 0.890411
400 ZZB 0.410256 0.77381
401 CNV FAD 0.410072 0.793103
402 SCA 0.409091 0.804598
403 RP1 0.409091 0.842105
404 103 0.409091 0.837838
405 2CP 0.409091 0.795455
406 SP1 0.409091 0.842105
407 PAX 0.408 0.829268
408 FAD NBT 0.407143 0.75
409 NVA 2AD 0.40625 0.74359
410 COW 0.406015 0.795455
411 BYC 0.406015 0.804598
412 2KQ 0.406015 0.786517
413 COF 0.406015 0.786517
414 3CP 0.406015 0.804598
415 IRC 0.406015 0.813953
416 1GZ 0.406015 0.795455
417 HGG 0.406015 0.804598
418 CA8 0.406015 0.729167
419 G2P 0.405941 0.884615
420 SLU 0.404959 0.770115
421 U A C C 0.404959 0.858974
422 RBZ 0.404494 0.849315
423 1CZ 0.404412 0.795455
424 BCA 0.402985 0.795455
425 FAQ 0.402985 0.804598
426 4CA 0.402985 0.795455
427 MTP 0.402439 0.730769
428 8OD 0.402062 0.945205
429 CO7 0.401515 0.804598
430 DAL FAD PER 0.401408 0.809524
431 G2R 0.4 0.884615
432 HXC 0.4 0.786517
433 ENQ 0.4 0.916667
434 GMV 0.4 0.896104
435 GRA 0.4 0.804598
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5LPB; Ligand: ADP; Similar sites found: 327
This union binding pocket(no: 1) in the query (biounit: 5lpb.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2IF8 ADP 0.0004026 0.47897 1.35135
2 3UDZ ADP 0.0000161 0.54653 2.02703
3 5MW8 ATP 0.00006696 0.52362 2.02703
4 2QK4 ATP 0.001001 0.4415 2.02703
5 1ELU CSS 0.01451 0.40751 2.02703
6 2VPQ ANP 0.0002233 0.49802 2.36486
7 5DXT 5H5 0.006057 0.4224 2.36486
8 1F76 FMN 0.02531 0.40154 2.36486
9 2GQR ADP 0.003504 0.42969 2.53165
10 1JXZ BCA 0.03013 0.40034 2.60223
11 3I0O ADP 0.00006668 0.50273 2.7027
12 2PUL ACP 0.00001699 0.49384 2.7027
13 2E9L BGC 0.04377 0.40165 2.7027
14 4OCJ NDG 0.0002874 0.51347 3.04054
15 5I35 ANP 0.000009975 0.50398 3.04054
16 2VQD AP2 0.0004052 0.42358 3.04054
17 4PZ6 GMP 0.001361 0.41177 3.04054
18 4AVB CMP 0.004192 0.41141 3.04054
19 3RE4 TO1 0.000007346 0.54738 3.10078
20 2QX0 PH2 0.01017 0.40907 3.14465
21 3VPC ADP 0.00003341 0.44664 3.19149
22 4R78 AMP 0.00001433 0.54177 3.37838
23 4OCV ANP 0.00007415 0.45069 3.37838
24 5TDF ADP 0.00177 0.45021 3.37838
25 5C1P ADP 0.0007937 0.44341 3.37838
26 1M3U KPL 0.002398 0.43533 3.40909
27 1ZTH ADP 0.000004408 0.55772 3.48837
28 1ZP9 ATP 0.000004502 0.52836 3.48837
29 1TQP ATP 0.0002913 0.40446 3.5461
30 4CYI ATP 0.000001319 0.60174 3.71622
31 5VZ0 ADP 0.0001707 0.49219 3.71622
32 4GYI ADP 0.0004689 0.45415 3.71622
33 5COU ATP 0.001338 0.44961 3.71622
34 1GPM AMP 0.02107 0.40408 3.71622
35 2CFM AMP 0.001024 0.44743 4.05405
36 3PN1 IVH 0.001708 0.42628 4.05405
37 1TZD ADP 0.00217 0.44117 4.36364
38 1M0W ANP 0.001083 0.45157 4.39189
39 3ETH ATP 0.003147 0.43996 4.39189
40 2YRX AMP 0.006528 0.42205 4.39189
41 3TY5 ADP 0.004988 0.42016 4.39189
42 3TY5 ATP 0.008475 0.40457 4.39189
43 1W2D ADP 0.0009754 0.44842 4.5283
44 3DJF BC3 0.02324 0.40055 4.52962
45 3VOT ADP 0.0001397 0.48776 4.72973
46 5IQD RIO 0.009132 0.43611 4.72973
47 5IQD GNP 0.008702 0.43611 4.72973
48 2IO8 ADP 0.0002066 0.40588 4.72973
49 1EHI ADP 0.001424 0.40431 4.72973
50 3Q60 ATP 0.00003092 0.48511 5.06757
51 4UWH JXM 0.001909 0.41871 5.06757
52 3AKK ADP 0.002412 0.40161 5.06757
53 3VPB ADP 0.00002753 0.43433 5.35714
54 3HAV ATP 0.0001032 0.51251 5.40541
55 4LH7 1X8 0.001362 0.45606 5.40541
56 4CC6 L5Y 0.001584 0.44397 5.40541
57 4B1L FRU 0.003567 0.43236 5.45455
58 1TUF AZ1 0.02033 0.40491 5.74324
59 1S9D AFB 0.0103 0.40062 5.91133
60 1S68 AMP 0.002612 0.41856 6.4257
61 4LRJ ANP 0.0001174 0.49993 6.50888
62 4OUC 5ID 0.000002256 0.54478 6.75676
63 3V4S ATP 0.00401 0.43482 6.75676
64 3V4S ADP 0.01688 0.4202 6.75676
65 5IGI ZIT 0.04456 0.4003 6.75676
66 5IGI GMP 0.0427 0.4003 6.75676
67 5MY8 RXZ 0.0000003709 0.63924 7.09459
68 4ZS4 ATP 0.00008344 0.45425 7.09459
69 5ML3 DL3 0.03898 0.40335 7.38255
70 1YFS ALA 0.01053 0.40609 7.43243
71 3PDT ADP 0.001008 0.43172 7.63636
72 4OAV ACP 0.00000004739 0.59696 7.77027
73 1IA9 ANP 0.00009575 0.45048 7.85714
74 4XYM A12 0.0002214 0.43364 8.26087
75 5FI4 5XV 0.005319 0.43224 8.44595
76 2PVN P63 0.00000006712 0.48605 8.78378
77 1T36 ADP 0.0009482 0.47423 8.78378
78 3X01 AMP 0.0009441 0.46258 8.78378
79 5TT5 NAD 0.003478 0.44297 8.78378
80 2BKK ADP 0.001644 0.43042 9.46746
81 2PYW ADP 0.00001877 0.54588 9.7973
82 4AZT LY2 0.001325 0.4422 10.1351
83 4Q5H ANP 0.0003894 0.43234 10.8974
84 4U98 ACP 0.001925 0.41253 11.4865
85 5M06 ADP 0.00000165 0.54572 11.5942
86 4IJP 1EH 0.000000003596 0.72597 13.1757
87 3M2W L8I 0.000001214 0.58757 13.1757
88 1HFE CYS 0.01766 0.40377 13.8211
89 3PE2 E1B 0.0000008354 0.6548 14.1892
90 4JR7 GNP 0.0000001434 0.56481 14.1892
91 5AWM ANP 0.00000004727 0.64952 14.527
92 1Q8Y ADP 0.00000001163 0.70126 14.8649
93 1Q8Y ADE 0.0000003573 0.59601 14.8649
94 4WB6 ATP 0.00000009787 0.6704 15.8784
95 4G17 0VN 0.0000008469 0.59849 15.8784
96 2QCS ANP 0.0000001208 0.66586 16.2162
97 1RE8 BD2 0.0000006928 0.65906 16.2162
98 4WOV 3SM 0.0000002251 0.60022 16.2162
99 5C03 AGS 0.0000007816 0.53437 16.2162
100 3IDB ANP 0.000000103 0.52094 16.2162
101 4WB7 ATP 0.0000001587 0.43671 16.2162
102 3FHI ANP 0.00000008771 0.67276 16.5541
103 4H3Q ANP 0.0000000003495 0.78215 17.5676
104 3FHR P4O 0.000002877 0.50244 17.5676
105 4O1P ANP 0.000000009332 0.69886 17.9054
106 2RIO ADP 0.00000005317 0.65909 18.9189
107 5GZ9 ANP 0.00000000256 0.73983 19.5946
108 5DMZ ADP 0.000003025 0.51595 19.5946
109 5VC5 96M 0.000000000542 0.78532 23.1834
110 3GNI ATP 0.000000004026 0.58868 23.6486
111 3VHE 42Q 0.0000002106 0.45501 25.3378
112 2ZV2 609 0.00000003123 0.65791 25.6757
113 3OFM 4B0 0.0000003503 0.61291 26.2857
114 2WU6 DKI 0.000000000268 0.60351 27.7027
115 3C0G 3AM 0.0000001554 0.60733 28.3784
116 2VN9 GVD 0.000000348 0.59625 29.0541
117 5VCV 1N1 0.0000000005602 0.57968 29.0541
118 2WEL K88 0.000001107 0.5481 29.0541
119 3PTG 932 0.000009507 0.53413 29.0541
120 2VZ6 FEF 0.00002206 0.51348 29.0541
121 3TTI KBI 0.0000001045 0.4856 29.0541
122 3GC0 AMP 0.0000001495 0.60937 29.3919
123 5X8I SQZ 0.00000001581 0.59937 29.3919
124 4UX9 ANP 0.000000138 0.53755 29.3919
125 4IZY 1J2 0.0000005301 0.51521 29.3919
126 3KN5 ANP 0.00006018 0.50796 29.3919
127 2V7O DRN 0.0000002987 0.59922 29.7297
128 4YLL 4E3 0.0000006029 0.62374 30.0676
129 4AU8 Z3R 0.0000001221 0.63032 30.4054
130 4Y0X ADP 0.00001027 0.54725 30.4054
131 4OTH DRN 0.000001423 0.50425 30.4054
132 2PZI AXX 0.00007546 0.48964 30.4054
133 4KBA 1QM 0.000003066 0.44891 30.4054
134 5W4W 9WG 0.000002111 0.43909 30.4054
135 3E7O 35F 0.000004934 0.41876 30.4054
136 4IDT T28 0.0000001307 0.58331 30.7432
137 2R5T ANP 0.000004507 0.48162 30.7432
138 1UNH IXM 0.0000000003444 0.72452 30.8219
139 3O0G 3O0 0.00000001684 0.68286 30.8219
140 3MVH WFE 0.0000004822 0.64278 31.0811
141 4BKJ STI 0.00003622 0.54095 31.0811
142 2Z7R STU 0.0000001579 0.53071 31.0811
143 1XJD STU 0.00000008095 0.56163 31.4189
144 2CSN CKI 0.0003661 0.52601 31.4189
145 3IGO ANP 0.000004622 0.4809 31.4189
146 5BYZ 4WE 0.000007085 0.43235 31.4189
147 4CLI 5P8 0.00000005519 0.71344 31.7568
148 5HQ0 LZ9 0.0000000004042 0.626 31.7568
149 4L3L 5FI 0.000001464 0.61855 31.7568
150 4H3P ANP 0.000000005906 0.61642 31.7568
151 4YZC STU 0.000003111 0.61294 31.7568
152 4Y8D 49J 0.00000005985 0.57848 31.7568
153 5T8O 76Z 0.00000002321 0.56578 31.7568
154 4BHN BH9 0.00000004093 0.56066 31.7568
155 4L9I 8PR 0.0003511 0.44748 31.7568
156 1OPK P16 0.000002178 0.43126 31.7568
157 4WNK 453 0.0000361 0.41655 31.7568
158 5KO1 6UY 0.00000002487 0.60514 31.8021
159 4QTB 38Z 0.00000001067 0.72342 32.0946
160 3TXO 07U 0.00000004178 0.66029 32.0946
161 3H9R TAK 0.0000003723 0.61764 32.0946
162 3ALN ANP 0.00000000389 0.58988 32.0946
163 4X7Q 3YR 0.0000002439 0.55673 32.0946
164 5HX8 66P 0.000000006493 0.52999 32.0946
165 3GC8 B45 0.000000206 0.5187 32.0946
166 2WEI VGG 0.00003817 0.49068 32.4042
167 5JZJ AN2 0.00000005073 0.59576 32.4324
168 5TA6 79D 0.0000002337 0.48075 32.4324
169 4CRL C1I 0.0000001775 0.44935 32.4324
170 4EWH T77 0.0000003716 0.47638 32.7273
171 5LI1 ANP 0.00000005614 0.67124 32.7703
172 4N70 2HX 0.00000184 0.63951 32.7703
173 1CM8 ANP 0.0000002203 0.62971 32.7703
174 3DLS ADP 0.0000007577 0.60077 32.7703
175 3V8S 0HD 0.0000007549 0.54834 32.7703
176 4I6H 1C8 0.000002982 0.51711 32.7703
177 5LI9 ACP 0.00000213 0.51156 32.7703
178 2XK9 XK9 0.005757 0.47233 32.7703
179 5G1X ADP 0.0000001769 0.57654 32.9825
180 5L8L ADP 0.000007938 0.54581 32.9825
181 1OUK 084 0.00001806 0.62418 33.1081
182 3GGF GVD 0.0000001773 0.59205 33.1081
183 4DC2 ADE 0.0000001358 0.56152 33.1081
184 4Y85 499 0.000001348 0.54378 33.1081
185 4LOO SB4 0.00002388 0.53563 33.1081
186 4EUU BX7 0.0000005489 0.47713 33.1081
187 4Y93 746 0.000002267 0.4658 33.1081
188 5LXM ADP 0.00000006465 0.5916 33.2155
189 1V0O INR 0.00000002594 0.58112 33.3333
190 5EYK 5U5 0.000002277 0.45627 33.3333
191 3BU5 ATP 0.000000006128 0.70761 33.4459
192 5EKO N17 0.00001366 0.5574 33.4459
193 5JKG 6LF 0.0001076 0.53543 33.4459
194 1VJY 460 0.0000000005529 0.50982 33.4459
195 3LXK MI1 0.000000044 0.50001 33.4459
196 3EKK GS2 0.00000001853 0.4502 33.4459
197 4JDI ANP 0.000000006509 0.71348 33.7838
198 3TKI S25 0.0000003019 0.68632 33.7838
199 2HY0 306 0.0000004179 0.58869 33.7838
200 4FL3 ANP 0.00000001019 0.5743 33.7838
201 4M69 ANP 0.00000003064 0.56601 33.7838
202 3VRY B43 0.0000000006696 0.56396 33.7838
203 4FG8 ATP 0.00004436 0.52778 33.7838
204 2J7T 274 0.01052 0.45182 33.7838
205 2QLU ADE 0.0000001868 0.65351 34.1216
206 5IH9 6BF 0.0000007675 0.64234 34.1216
207 2H8H H8H 0.000000008673 0.60797 34.1216
208 4BFM ANP 0.00000002963 0.56474 34.1216
209 1Y57 MPZ 0.000000009884 0.55299 34.1216
210 2F57 23D 0.000001712 0.55062 34.1216
211 2X4Z X4Z 0.0000004231 0.4416 34.1216
212 3SXF BK5 0.00000179 0.41852 34.1216
213 4C2V YJA 0.000003383 0.4424 34.386
214 5TO8 7FM 0.000001296 0.40756 34.3972
215 2XMY CDK 0.000000346 0.695 34.4595
216 1U5R ATP 0.0000000003448 0.65931 34.4595
217 3RI1 3RH 0.0000009252 0.62199 34.4595
218 3NW7 LGV 0.000003918 0.61961 34.4595
219 1K3A ACP 0.0000002404 0.59906 34.4595
220 2PVF ACP 0.00000004516 0.59749 34.4595
221 5DH3 5BS 0.0000003929 0.52697 34.4595
222 3CY2 MB9 0.0000001401 0.52282 34.4595
223 3PP0 03Q 0.00000003043 0.50519 34.4595
224 5USZ SKE 0.000000005713 0.52034 34.6021
225 4XLI 1N1 0.00000007671 0.58752 34.7015
226 3AQV TAK 0.00005114 0.51979 34.7826
227 4BCN T9N 0.000000001335 0.69855 34.7973
228 4CFU 2WC 0.0000000005807 0.69232 34.7973
229 4BCM T7Z 0.00000002329 0.68744 34.7973
230 4USF 6UI 0.00000006244 0.67476 34.7973
231 5CEO 50D 0.0000000496 0.66411 34.7973
232 4BCQ TJF 0.00000005951 0.64486 34.7973
233 5LMK 6ZK 0.00000177 0.58336 34.7973
234 4FF8 14S 0.00002119 0.52594 34.7973
235 4AUA 4AU 0.000008161 0.51432 34.7973
236 4WNP 3RJ 0.00000000417 0.67722 34.8432
237 3G5D 1N1 0.00000004733 0.73184 34.965
238 5UOX 8GY 0.0000000279 0.55398 35.0554
239 4TWP AXI 0.00000006889 0.40353 35.0554
240 4C2W ANP 0.000001964 0.57409 35.1254
241 5JFS 6K0 0.000000004486 0.76469 35.1351
242 2B9F ADP 0.00000000518 0.7111 35.1351
243 2B9H ADP 0.000000007773 0.70629 35.1351
244 3SLS ANP 0.0000000002719 0.61783 35.1351
245 2B9J ADP 0.00000002403 0.60999 35.1351
246 4F9C 0SX 0.000001107 0.59634 35.1351
247 2B9I ADP 0.00000002476 0.59451 35.1351
248 5UR1 YY9 0.00001384 0.58695 35.1351
249 3GQI ACP 0.0000004139 0.54776 35.1351
250 5UKL SIX 0.0003393 0.49647 35.1351
251 3ORK AGS 0.00001724 0.44906 35.1351
252 3PVW QRX 0.000162 0.41269 35.1351
253 3DAK ANP 0.000001351 0.55263 35.1724
254 5EW9 5VC 0.000006645 0.64873 35.4244
255 3E5A VX6 0.000002273 0.47437 35.4478
256 2X2M X2M 0.00000002323 0.6899 35.473
257 4K33 ACP 0.00000007663 0.65841 35.473
258 5U6C 7YS 0.000000003805 0.58034 35.473
259 4E93 GUI 0.000000001037 0.50263 35.473
260 4NW6 2NS 0.00000006149 0.46481 35.473
261 3E8N ATP 0.0000000003947 0.44065 35.473
262 3E8N VRA 0.0000000003947 0.44065 35.473
263 3KMW ATP 0.00000001975 0.6156 35.7934
264 5EFQ ADP 0.0000000005553 0.75755 35.8108
265 1PHK ATP 0.00000002672 0.68045 35.8108
266 4NST ADP 0.000000001167 0.64028 35.8108
267 5AX9 4KT 0.000000007065 0.614 35.8108
268 3PLS ANP 0.00000002625 0.60704 35.8108
269 4AT3 LTI 0.00000005013 0.47559 35.8108
270 4YMJ 4EJ 0.00000000316 0.74009 36.1486
271 3ZRM ZRM 0.00000004066 0.66825 36.1486
272 3F7Z 34O 0.00000006071 0.65991 36.1486
273 2OO8 RAJ 0.00008018 0.43117 36.1486
274 2A19 ANP 0.00000176 0.57631 36.2676
275 3KRR DQX 0.00000004983 0.73945 36.2712
276 1ZY5 ANP 0.000004103 0.56926 36.8243
277 4NM5 ADP 0.00000002107 0.54738 36.8243
278 3HZT J60 0.00002005 0.52705 36.8243
279 5JGA 6KC 0.00000001607 0.48401 36.8243
280 2YAB AMP 0.00004831 0.46443 36.8243
281 2JLD AG1 0.000001259 0.43424 36.8243
282 4KS7 X4Z 0.0000001992 0.51758 36.9863
283 2HK5 1BM 0.0000000188 0.69116 37.037
284 3SRV S19 0.0000000005051 0.75535 37.1841
285 4CSV STI 0.000001628 0.48286 37.4545
286 2Y6O 1N1 0.00000002244 0.54471 37.457
287 4F4P 0SB 0.00000005938 0.73047 37.7289
288 5NKB 8ZT 0.00000003062 0.42159 37.8378
289 5HCY 60D 0.00000005359 0.41526 37.8378
290 4U44 3D9 0.0000003502 0.62346 38.1757
291 5N87 N66 0.000001222 0.42213 38.1757
292 2YAK OSV 0.00001583 0.41857 38.2456
293 4A4X JUP 0.00000002042 0.51704 38.3513
294 4I94 ANP 0.0000003163 0.62223 38.5135
295 3HMO STU 0.0000001616 0.57398 38.8514
296 4BTK DTQ 0.00002502 0.53466 38.8514
297 4NFN 2KC 0.00001665 0.49178 38.8514
298 4ASE AV9 0.0000003044 0.4645 38.8514
299 4AG8 AXI 0.000001108 0.41215 38.8514
300 2OFV 242 0.00000005878 0.44671 38.9892
301 3KRL KRL 0.000003838 0.48478 39.1892
302 4QMN DB8 0.0000008024 0.42137 39.527
303 4P5Z Q7M 0.00000002478 0.43736 39.8649
304 5A6N U7E 0.00001977 0.54224 39.9293
305 5LVP ATP 0.000008211 0.54858 40
306 1U59 STU 0.0000003581 0.55303 40.4181
307 5H2U 1N1 0.000000002714 0.62553 40.4494
308 5DA3 58V 0.000000005919 0.69158 40.7547
309 4D2S DYK 0.0000005635 0.60322 40.8451
310 1JPA ANP 0.000000001299 0.78396 41.2162
311 2XVD AS6 0.00000003472 0.48927 41.2162
312 4YZN 4K5 0.00000006694 0.53449 41.4634
313 2WQN ADP 0.000004994 0.53981 41.5541
314 5HES 032 0.00000001808 0.69521 41.8919
315 5MJA 7O3 0.00000004894 0.65704 41.8919
316 4E1Z 0MX 0.0000004729 0.50482 42.6117
317 5FBN 5WF 0.0000001188 0.68179 42.8044
318 4XV1 904 0.0000001229 0.67903 43.4931
319 3LXN MI1 0.000000007133 0.58502 44.2568
320 4GJ3 0XP 0.000000002369 0.50864 44.5946
321 3C1X CKK 0.00001102 0.46663 44.9324
322 5EOB 5QQ 0.000000275 0.68977 45.2703
323 1BYG STU 0.00000002027 0.62893 45.6835
324 4CQE CQE 0.0000004105 0.50737 45.6835
325 4U0I 0LI 0.000001202 0.43015 45.9459
326 3SXS PP2 0.00000002024 0.56141 46.2687
327 5HVJ ANP 0.0000007029 0.62192 46.6216
Feedback